Motif ID: JUN
Z-value: 2.474
Transcription factors associated with JUN:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| JUN | ENSG00000177606.5 | JUN |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 3.7 | GO:0051503 | purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) |
| 0.8 | 2.4 | GO:0070886 | positive regulation of calcineurin-NFAT signaling cascade(GO:0070886) |
| 0.8 | 3.0 | GO:0030035 | microspike assembly(GO:0030035) |
| 0.7 | 4.8 | GO:0042989 | sequestering of actin monomers(GO:0042989) |
| 0.6 | 1.7 | GO:0051365 | cellular response to potassium ion starvation(GO:0051365) |
| 0.5 | 8.2 | GO:0034446 | substrate adhesion-dependent cell spreading(GO:0034446) |
| 0.5 | 1.6 | GO:0032988 | ribonucleoprotein complex disassembly(GO:0032988) |
| 0.5 | 1.5 | GO:0014028 | notochord formation(GO:0014028) axial mesoderm morphogenesis(GO:0048319) |
| 0.5 | 1.5 | GO:0016476 | regulation of embryonic cell shape(GO:0016476) |
| 0.4 | 6.5 | GO:0007567 | parturition(GO:0007567) |
| 0.4 | 2.3 | GO:0006931 | substrate-dependent cell migration, cell attachment to substrate(GO:0006931) |
| 0.4 | 2.2 | GO:0014012 | peripheral nervous system axon regeneration(GO:0014012) |
| 0.3 | 2.0 | GO:0051387 | negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387) |
| 0.3 | 1.7 | GO:0071277 | cellular response to calcium ion(GO:0071277) |
| 0.3 | 6.6 | GO:0035329 | hippo signaling(GO:0035329) |
| 0.3 | 0.8 | GO:0002384 | hepatic immune response(GO:0002384) positive regulation of transmission of nerve impulse(GO:0051971) |
| 0.3 | 0.5 | GO:0070672 | response to interleukin-15(GO:0070672) |
| 0.3 | 7.1 | GO:0042730 | fibrinolysis(GO:0042730) |
| 0.3 | 1.0 | GO:0051901 | positive regulation of mitochondrial depolarization(GO:0051901) positive regulation of membrane depolarization(GO:1904181) |
| 0.2 | 2.0 | GO:0001553 | luteinization(GO:0001553) |
| 0.2 | 0.7 | GO:0032650 | regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730) |
| 0.2 | 6.7 | GO:0042554 | superoxide anion generation(GO:0042554) |
| 0.2 | 0.9 | GO:0015917 | aminophospholipid transport(GO:0015917) |
| 0.2 | 0.7 | GO:0010966 | regulation of phosphate transport(GO:0010966) |
| 0.2 | 1.1 | GO:0007182 | common-partner SMAD protein phosphorylation(GO:0007182) |
| 0.2 | 0.6 | GO:0007195 | adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195) |
| 0.2 | 0.6 | GO:0010891 | negative regulation of sequestering of triglyceride(GO:0010891) |
| 0.2 | 0.6 | GO:0060689 | cell differentiation involved in salivary gland development(GO:0060689) |
| 0.2 | 0.6 | GO:0048549 | positive regulation of pinocytosis(GO:0048549) |
| 0.2 | 7.0 | GO:0050873 | brown fat cell differentiation(GO:0050873) |
| 0.2 | 2.0 | GO:0001706 | endoderm formation(GO:0001706) |
| 0.2 | 1.5 | GO:0006622 | protein targeting to lysosome(GO:0006622) protein targeting to vacuole(GO:0006623) protein localization to lysosome(GO:0061462) protein localization to vacuole(GO:0072665) establishment of protein localization to vacuole(GO:0072666) |
| 0.2 | 0.9 | GO:0002036 | regulation of L-glutamate transport(GO:0002036) |
| 0.1 | 0.4 | GO:0033590 | response to cobalamin(GO:0033590) |
| 0.1 | 1.5 | GO:0031017 | exocrine pancreas development(GO:0031017) |
| 0.1 | 2.3 | GO:1902749 | regulation of G2/M transition of mitotic cell cycle(GO:0010389) regulation of cell cycle G2/M phase transition(GO:1902749) |
| 0.1 | 1.3 | GO:0070536 | protein K63-linked deubiquitination(GO:0070536) |
| 0.1 | 0.4 | GO:0006423 | cysteinyl-tRNA aminoacylation(GO:0006423) |
| 0.1 | 0.3 | GO:0045603 | positive regulation of endothelial cell differentiation(GO:0045603) |
| 0.1 | 0.8 | GO:0051665 | membrane raft localization(GO:0051665) |
| 0.1 | 0.5 | GO:0002019 | regulation of renal output by angiotensin(GO:0002019) |
| 0.1 | 4.6 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
| 0.1 | 1.2 | GO:0015014 | heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014) |
| 0.1 | 1.1 | GO:0007216 | G-protein coupled glutamate receptor signaling pathway(GO:0007216) |
| 0.1 | 0.4 | GO:0006669 | sphinganine-1-phosphate biosynthetic process(GO:0006669) |
| 0.1 | 2.8 | GO:0030199 | collagen fibril organization(GO:0030199) |
| 0.1 | 0.8 | GO:0070584 | mitochondrion morphogenesis(GO:0070584) |
| 0.1 | 0.5 | GO:0071392 | cellular response to estradiol stimulus(GO:0071392) |
| 0.1 | 0.6 | GO:0021520 | spinal cord motor neuron cell fate specification(GO:0021520) |
| 0.1 | 5.0 | GO:0070936 | protein K48-linked ubiquitination(GO:0070936) |
| 0.1 | 1.1 | GO:0051497 | negative regulation of stress fiber assembly(GO:0051497) |
| 0.1 | 0.8 | GO:0043982 | histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982) |
| 0.1 | 0.6 | GO:0007341 | penetration of zona pellucida(GO:0007341) |
| 0.1 | 0.6 | GO:0045116 | protein neddylation(GO:0045116) |
| 0.1 | 0.4 | GO:0008628 | hormone-mediated apoptotic signaling pathway(GO:0008628) |
| 0.1 | 0.5 | GO:0019985 | translesion synthesis(GO:0019985) |
| 0.1 | 1.8 | GO:0045104 | intermediate filament cytoskeleton organization(GO:0045104) |
| 0.1 | 1.4 | GO:0051281 | positive regulation of release of sequestered calcium ion into cytosol(GO:0051281) |
| 0.1 | 2.5 | GO:0031572 | G2 DNA damage checkpoint(GO:0031572) |
| 0.1 | 1.5 | GO:0014003 | oligodendrocyte development(GO:0014003) |
| 0.1 | 0.8 | GO:0032922 | circadian regulation of gene expression(GO:0032922) |
| 0.1 | 1.3 | GO:0006198 | cAMP catabolic process(GO:0006198) |
| 0.1 | 1.3 | GO:0010332 | response to gamma radiation(GO:0010332) |
| 0.1 | 0.5 | GO:0051294 | establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294) |
| 0.1 | 0.8 | GO:0006998 | nuclear envelope organization(GO:0006998) |
| 0.1 | 0.8 | GO:0043537 | negative regulation of blood vessel endothelial cell migration(GO:0043537) |
| 0.1 | 0.3 | GO:1903963 | arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963) |
| 0.1 | 0.5 | GO:0009396 | folic acid-containing compound biosynthetic process(GO:0009396) |
| 0.1 | 2.0 | GO:0030866 | cortical actin cytoskeleton organization(GO:0030866) |
| 0.1 | 0.2 | GO:0071801 | podosome assembly(GO:0071800) regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803) |
| 0.0 | 4.1 | GO:0030049 | muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275) |
| 0.0 | 1.5 | GO:0001676 | long-chain fatty acid metabolic process(GO:0001676) |
| 0.0 | 1.0 | GO:0035196 | production of miRNAs involved in gene silencing by miRNA(GO:0035196) |
| 0.0 | 0.1 | GO:0046604 | regulation of mitotic centrosome separation(GO:0046602) positive regulation of mitotic centrosome separation(GO:0046604) |
| 0.0 | 0.8 | GO:0006071 | glycerol metabolic process(GO:0006071) |
| 0.0 | 0.1 | GO:0043276 | anoikis(GO:0043276) |
| 0.0 | 0.1 | GO:0016264 | gap junction assembly(GO:0016264) |
| 0.0 | 0.3 | GO:0007500 | mesodermal cell fate determination(GO:0007500) |
| 0.0 | 0.3 | GO:0001514 | selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451) |
| 0.0 | 1.8 | GO:0033344 | cholesterol efflux(GO:0033344) |
| 0.0 | 0.5 | GO:0034643 | establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497) |
| 0.0 | 1.6 | GO:0032436 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800) |
| 0.0 | 0.1 | GO:0042415 | norepinephrine metabolic process(GO:0042415) |
| 0.0 | 1.4 | GO:0007026 | negative regulation of microtubule depolymerization(GO:0007026) |
| 0.0 | 9.1 | GO:0007517 | muscle organ development(GO:0007517) |
| 0.0 | 10.0 | GO:0001558 | regulation of cell growth(GO:0001558) |
| 0.0 | 0.4 | GO:0055015 | ventricular cardiac muscle cell development(GO:0055015) |
| 0.0 | 0.5 | GO:0030212 | hyaluronan metabolic process(GO:0030212) |
| 0.0 | 1.3 | GO:0030520 | intracellular estrogen receptor signaling pathway(GO:0030520) |
| 0.0 | 0.1 | GO:0045885 | obsolete positive regulation of survival gene product expression(GO:0045885) |
| 0.0 | 0.3 | GO:0016998 | cell wall macromolecule catabolic process(GO:0016998) |
| 0.0 | 0.4 | GO:0043171 | peptide catabolic process(GO:0043171) |
| 0.0 | 0.2 | GO:0030813 | positive regulation of nucleotide catabolic process(GO:0030813) positive regulation of glycolytic process(GO:0045821) positive regulation of nucleoside metabolic process(GO:0045979) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197) positive regulation of ATP metabolic process(GO:1903580) |
| 0.0 | 0.1 | GO:0040020 | regulation of meiotic nuclear division(GO:0040020) |
| 0.0 | 0.3 | GO:0071157 | negative regulation of cell cycle arrest(GO:0071157) |
| 0.0 | 0.2 | GO:0007052 | mitotic spindle organization(GO:0007052) |
| 0.0 | 0.9 | GO:0043966 | histone H3 acetylation(GO:0043966) |
| 0.0 | 0.3 | GO:0001937 | negative regulation of endothelial cell proliferation(GO:0001937) |
| 0.0 | 1.1 | GO:0007043 | cell-cell junction assembly(GO:0007043) |
| 0.0 | 0.2 | GO:0042797 | 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797) |
| 0.0 | 0.8 | GO:0007368 | determination of left/right symmetry(GO:0007368) |
| 0.0 | 0.5 | GO:0032400 | melanosome localization(GO:0032400) |
| 0.0 | 0.2 | GO:0033540 | fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540) |
| 0.0 | 0.2 | GO:0033523 | histone monoubiquitination(GO:0010390) histone H2B ubiquitination(GO:0033523) |
| 0.0 | 1.2 | GO:0030183 | B cell differentiation(GO:0030183) |
| 0.0 | 3.7 | GO:0007015 | actin filament organization(GO:0007015) |
| 0.0 | 1.2 | GO:0006937 | regulation of muscle contraction(GO:0006937) |
| 0.0 | 0.5 | GO:0006699 | bile acid biosynthetic process(GO:0006699) |
| 0.0 | 3.0 | GO:0006415 | translational termination(GO:0006415) |
| 0.0 | 1.1 | GO:0007204 | positive regulation of cytosolic calcium ion concentration(GO:0007204) |
| 0.0 | 0.1 | GO:0001969 | activation of membrane attack complex(GO:0001905) regulation of activation of membrane attack complex(GO:0001969) positive regulation of activation of membrane attack complex(GO:0001970) positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259) |
| 0.0 | 0.9 | GO:0006914 | autophagy(GO:0006914) |
| 0.0 | 0.1 | GO:0035964 | COPI-coated vesicle budding(GO:0035964) Golgi vesicle budding(GO:0048194) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205) |
| 0.0 | 0.7 | GO:0050690 | regulation of defense response to virus by virus(GO:0050690) |
| 0.0 | 0.0 | GO:0001544 | initiation of primordial ovarian follicle growth(GO:0001544) |
| 0.0 | 0.4 | GO:0016042 | lipid catabolic process(GO:0016042) |
| 0.0 | 0.4 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
| 0.0 | 0.2 | GO:0051924 | regulation of calcium ion transport(GO:0051924) |
| 0.0 | 0.7 | GO:0071377 | cellular response to glucagon stimulus(GO:0071377) |
| 0.0 | 0.2 | GO:0032008 | positive regulation of TOR signaling(GO:0032008) |
| 0.0 | 2.4 | GO:0097485 | axon guidance(GO:0007411) neuron projection guidance(GO:0097485) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.1 | 3.3 | GO:0005588 | collagen type V trimer(GO:0005588) |
| 0.7 | 8.2 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.6 | 8.2 | GO:0098647 | collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647) |
| 0.5 | 7.5 | GO:0005606 | laminin-1 complex(GO:0005606) |
| 0.4 | 2.1 | GO:0033270 | paranode region of axon(GO:0033270) |
| 0.3 | 3.7 | GO:0005916 | fascia adherens(GO:0005916) |
| 0.3 | 1.8 | GO:1990752 | microtubule plus-end(GO:0035371) microtubule end(GO:1990752) |
| 0.2 | 0.9 | GO:0000306 | extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313) |
| 0.2 | 4.3 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
| 0.2 | 0.8 | GO:0005896 | interleukin-6 receptor complex(GO:0005896) |
| 0.2 | 1.6 | GO:0000145 | exocyst(GO:0000145) |
| 0.1 | 13.5 | GO:0016459 | myosin complex(GO:0016459) |
| 0.1 | 0.4 | GO:0043512 | inhibin complex(GO:0043511) inhibin A complex(GO:0043512) |
| 0.1 | 1.0 | GO:0005869 | dynactin complex(GO:0005869) |
| 0.1 | 0.9 | GO:0033179 | proton-transporting V-type ATPase, V0 domain(GO:0033179) |
| 0.1 | 1.7 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 0.1 | 3.5 | GO:0005776 | autophagosome(GO:0005776) |
| 0.1 | 0.9 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 0.1 | 0.9 | GO:0005678 | obsolete chromatin assembly complex(GO:0005678) |
| 0.1 | 0.6 | GO:0019907 | cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907) |
| 0.1 | 0.5 | GO:0070776 | H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776) |
| 0.1 | 1.4 | GO:0031105 | septin complex(GO:0031105) septin cytoskeleton(GO:0032156) |
| 0.1 | 1.5 | GO:0045335 | phagocytic vesicle(GO:0045335) |
| 0.1 | 0.5 | GO:0042575 | DNA polymerase complex(GO:0042575) |
| 0.1 | 1.0 | GO:0008091 | spectrin(GO:0008091) |
| 0.1 | 0.2 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
| 0.1 | 6.7 | GO:0001726 | ruffle(GO:0001726) |
| 0.1 | 4.3 | GO:0030496 | midbody(GO:0030496) |
| 0.1 | 0.4 | GO:0031674 | I band(GO:0031674) |
| 0.0 | 2.3 | GO:0043204 | perikaryon(GO:0043204) |
| 0.0 | 0.3 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
| 0.0 | 0.4 | GO:0000125 | PCAF complex(GO:0000125) |
| 0.0 | 0.6 | GO:0042581 | specific granule(GO:0042581) |
| 0.0 | 13.3 | GO:0015629 | actin cytoskeleton(GO:0015629) |
| 0.0 | 0.5 | GO:0005868 | cytoplasmic dynein complex(GO:0005868) |
| 0.0 | 0.1 | GO:0033011 | perinuclear theca(GO:0033011) cytoskeletal calyx(GO:0033150) |
| 0.0 | 1.5 | GO:0030027 | lamellipodium(GO:0030027) |
| 0.0 | 0.2 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.0 | 1.6 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.0 | 0.8 | GO:0005811 | lipid particle(GO:0005811) |
| 0.0 | 0.2 | GO:0000127 | transcription factor TFIIIC complex(GO:0000127) |
| 0.0 | 2.4 | GO:0015934 | large ribosomal subunit(GO:0015934) |
| 0.0 | 1.8 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
| 0.0 | 2.6 | GO:0005875 | microtubule associated complex(GO:0005875) |
| 0.0 | 0.7 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
| 0.0 | 1.3 | GO:0005626 | obsolete insoluble fraction(GO:0005626) |
| 0.0 | 0.5 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
| 0.0 | 2.9 | GO:0005925 | focal adhesion(GO:0005925) |
| 0.0 | 0.1 | GO:0001741 | XY body(GO:0001741) |
| 0.0 | 8.0 | GO:0031012 | extracellular matrix(GO:0031012) |
| 0.0 | 0.5 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 0.0 | 0.6 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
| 0.0 | 0.4 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
| 0.0 | 5.4 | GO:0005667 | transcription factor complex(GO:0005667) |
| 0.0 | 0.1 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
| 0.0 | 0.1 | GO:0030126 | COPI vesicle coat(GO:0030126) |
| 0.0 | 1.4 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
| 0.0 | 0.5 | GO:0036064 | ciliary basal body(GO:0036064) |
| 0.0 | 0.8 | GO:0000123 | histone acetyltransferase complex(GO:0000123) protein acetyltransferase complex(GO:0031248) acetyltransferase complex(GO:1902493) |
| 0.0 | 18.2 | GO:0005576 | extracellular region(GO:0005576) |
| 0.0 | 1.1 | GO:0043025 | neuronal cell body(GO:0043025) |
| 0.0 | 0.1 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
| 0.0 | 0.9 | GO:0030139 | endocytic vesicle(GO:0030139) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 6.7 | GO:0019826 | oxygen sensor activity(GO:0019826) |
| 0.6 | 1.8 | GO:0004947 | bradykinin receptor activity(GO:0004947) |
| 0.6 | 2.3 | GO:0047499 | calcium-independent phospholipase A2 activity(GO:0047499) |
| 0.4 | 2.0 | GO:0008330 | protein tyrosine/threonine phosphatase activity(GO:0008330) |
| 0.4 | 10.3 | GO:0005520 | insulin-like growth factor binding(GO:0005520) |
| 0.3 | 1.0 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
| 0.3 | 3.7 | GO:0005243 | gap junction channel activity(GO:0005243) |
| 0.3 | 0.9 | GO:0015247 | aminophospholipid transporter activity(GO:0015247) |
| 0.3 | 1.2 | GO:0042328 | heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328) N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509) |
| 0.3 | 0.8 | GO:0031755 | endothelial differentiation G-protein coupled receptor binding(GO:0031753) Edg-2 lysophosphatidic acid receptor binding(GO:0031755) |
| 0.2 | 0.7 | GO:0030276 | clathrin binding(GO:0030276) |
| 0.2 | 2.3 | GO:0004862 | cAMP-dependent protein kinase inhibitor activity(GO:0004862) |
| 0.2 | 0.6 | GO:0042806 | fucose binding(GO:0042806) |
| 0.2 | 3.1 | GO:0003785 | actin monomer binding(GO:0003785) |
| 0.2 | 1.8 | GO:0050811 | GABA receptor binding(GO:0050811) |
| 0.2 | 0.9 | GO:0004597 | peptide-aspartate beta-dioxygenase activity(GO:0004597) |
| 0.2 | 19.0 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.2 | 0.6 | GO:0019788 | NEDD8 transferase activity(GO:0019788) |
| 0.1 | 0.4 | GO:0004817 | cysteine-tRNA ligase activity(GO:0004817) |
| 0.1 | 0.6 | GO:0031702 | type 1 angiotensin receptor binding(GO:0031702) |
| 0.1 | 1.6 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
| 0.1 | 0.6 | GO:0017160 | Ral GTPase binding(GO:0017160) |
| 0.1 | 0.4 | GO:0048184 | obsolete follistatin binding(GO:0048184) |
| 0.1 | 0.5 | GO:0016882 | cyclo-ligase activity(GO:0016882) |
| 0.1 | 0.8 | GO:0008889 | glycerophosphodiester phosphodiesterase activity(GO:0008889) |
| 0.1 | 2.9 | GO:0016755 | transferase activity, transferring amino-acyl groups(GO:0016755) |
| 0.1 | 1.4 | GO:0043395 | heparan sulfate proteoglycan binding(GO:0043395) |
| 0.1 | 0.7 | GO:0042731 | PH domain binding(GO:0042731) |
| 0.1 | 1.0 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
| 0.1 | 0.8 | GO:0005138 | interleukin-6 receptor binding(GO:0005138) |
| 0.1 | 4.2 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
| 0.1 | 0.9 | GO:0004579 | dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
| 0.1 | 1.2 | GO:0030346 | protein phosphatase 2B binding(GO:0030346) |
| 0.1 | 1.5 | GO:0005003 | ephrin receptor activity(GO:0005003) |
| 0.1 | 0.5 | GO:0008241 | peptidyl-dipeptidase activity(GO:0008241) |
| 0.1 | 2.4 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 0.1 | 8.3 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.1 | 0.3 | GO:0003796 | lysozyme activity(GO:0003796) |
| 0.1 | 1.7 | GO:0004623 | phospholipase A2 activity(GO:0004623) |
| 0.1 | 1.1 | GO:0043274 | phospholipase binding(GO:0043274) |
| 0.1 | 0.2 | GO:0016402 | pristanoyl-CoA oxidase activity(GO:0016402) |
| 0.1 | 1.0 | GO:0001619 | obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619) |
| 0.1 | 5.6 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 0.1 | 0.6 | GO:0042153 | obsolete RPTP-like protein binding(GO:0042153) |
| 0.1 | 0.4 | GO:0017050 | sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050) |
| 0.1 | 1.6 | GO:0070412 | R-SMAD binding(GO:0070412) |
| 0.1 | 1.3 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.1 | 0.2 | GO:0005137 | interleukin-5 receptor binding(GO:0005137) |
| 0.1 | 0.2 | GO:0004321 | fatty-acyl-CoA synthase activity(GO:0004321) |
| 0.1 | 0.5 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.1 | 1.3 | GO:0045028 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
| 0.0 | 0.4 | GO:0015379 | potassium:chloride symporter activity(GO:0015379) |
| 0.0 | 21.0 | GO:0003779 | actin binding(GO:0003779) |
| 0.0 | 0.2 | GO:0043891 | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891) |
| 0.0 | 0.2 | GO:0016286 | small conductance calcium-activated potassium channel activity(GO:0016286) |
| 0.0 | 0.7 | GO:0070063 | RNA polymerase binding(GO:0070063) |
| 0.0 | 0.4 | GO:0042301 | phosphate ion binding(GO:0042301) |
| 0.0 | 0.3 | GO:0004800 | thyroxine 5'-deiodinase activity(GO:0004800) |
| 0.0 | 0.5 | GO:0016944 | obsolete RNA polymerase II transcription elongation factor activity(GO:0016944) |
| 0.0 | 0.5 | GO:0015355 | secondary active monocarboxylate transmembrane transporter activity(GO:0015355) |
| 0.0 | 0.2 | GO:0015280 | ligand-gated sodium channel activity(GO:0015280) |
| 0.0 | 4.3 | GO:0016881 | acid-amino acid ligase activity(GO:0016881) |
| 0.0 | 0.4 | GO:0061659 | ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659) |
| 0.0 | 1.3 | GO:0045182 | translation regulator activity(GO:0045182) |
| 0.0 | 0.7 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.0 | 0.8 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
| 0.0 | 0.5 | GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding(GO:0005546) |
| 0.0 | 0.8 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
| 0.0 | 1.6 | GO:0032947 | protein complex scaffold(GO:0032947) |
| 0.0 | 0.4 | GO:0001786 | phosphatidylserine binding(GO:0001786) |
| 0.0 | 5.5 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.0 | 2.8 | GO:0004197 | cysteine-type endopeptidase activity(GO:0004197) |
| 0.0 | 3.9 | GO:0035257 | nuclear hormone receptor binding(GO:0035257) |
| 0.0 | 0.6 | GO:0015929 | hexosaminidase activity(GO:0015929) |
| 0.0 | 0.5 | GO:0008395 | steroid hydroxylase activity(GO:0008395) |
| 0.0 | 0.5 | GO:0016500 | protein-hormone receptor activity(GO:0016500) |
| 0.0 | 0.7 | GO:0019003 | GDP binding(GO:0019003) |
| 0.0 | 0.1 | GO:0046935 | 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935) |
| 0.0 | 0.4 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 0.0 | 0.5 | GO:0005246 | calcium channel regulator activity(GO:0005246) |
| 0.0 | 1.7 | GO:0031625 | ubiquitin protein ligase binding(GO:0031625) ubiquitin-like protein ligase binding(GO:0044389) |
| 0.0 | 2.1 | GO:0003774 | motor activity(GO:0003774) |
| 0.0 | 0.1 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
| 0.0 | 0.5 | GO:0008603 | cAMP-dependent protein kinase regulator activity(GO:0008603) |
| 0.0 | 0.2 | GO:0008200 | ion channel inhibitor activity(GO:0008200) |
| 0.0 | 0.1 | GO:0045502 | dynein binding(GO:0045502) |
| 0.0 | 0.4 | GO:0004385 | guanylate kinase activity(GO:0004385) |
| 0.0 | 1.5 | GO:0008135 | translation factor activity, RNA binding(GO:0008135) |
| 0.0 | 0.3 | GO:0005242 | inward rectifier potassium channel activity(GO:0005242) |
| 0.0 | 0.5 | GO:0097472 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472) |
| 0.0 | 0.1 | GO:0047429 | nucleoside-triphosphate diphosphatase activity(GO:0047429) |
| 0.0 | 0.1 | GO:0016714 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714) dopamine binding(GO:0035240) |
| 0.0 | 1.0 | GO:0031072 | heat shock protein binding(GO:0031072) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.7 | SA_B_CELL_RECEPTOR_COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
| 0.0 | 0.8 | ST_STAT3_PATHWAY | STAT3 Pathway |
| 0.0 | 2.0 | SIG_CD40PATHWAYMAP | Genes related to CD40 signaling |
| 0.0 | 1.9 | SIG_CHEMOTAXIS | Genes related to chemotaxis |
| 0.0 | 0.5 | ST_G_ALPHA_I_PATHWAY | G alpha i Pathway |
| 0.0 | 0.6 | ST_JNK_MAPK_PATHWAY | JNK MAPK Pathway |
