Motif ID: JUND
Z-value: 1.848
Transcription factors associated with JUND:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| JUND | ENSG00000130522.4 | JUND |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.0 | 6.1 | GO:0000738 | DNA catabolic process, exonucleolytic(GO:0000738) |
| 1.2 | 3.7 | GO:0035408 | histone H3-T6 phosphorylation(GO:0035408) |
| 0.9 | 4.6 | GO:0006216 | cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087) |
| 0.4 | 1.3 | GO:0010430 | ethanol catabolic process(GO:0006068) fatty acid omega-oxidation(GO:0010430) |
| 0.3 | 1.3 | GO:0071218 | cellular response to misfolded protein(GO:0071218) |
| 0.3 | 1.6 | GO:0046642 | negative regulation of alpha-beta T cell proliferation(GO:0046642) |
| 0.3 | 0.9 | GO:0035021 | negative regulation of Rac protein signal transduction(GO:0035021) |
| 0.3 | 5.3 | GO:0032814 | regulation of natural killer cell activation(GO:0032814) |
| 0.3 | 2.8 | GO:0031017 | exocrine pancreas development(GO:0031017) |
| 0.2 | 3.7 | GO:0045885 | obsolete positive regulation of survival gene product expression(GO:0045885) |
| 0.2 | 0.6 | GO:0006419 | alanyl-tRNA aminoacylation(GO:0006419) |
| 0.2 | 1.9 | GO:0022417 | protein maturation by protein folding(GO:0022417) |
| 0.2 | 0.8 | GO:0045938 | regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) positive regulation of circadian sleep/wake cycle, sleep(GO:0045938) |
| 0.2 | 1.3 | GO:0036037 | maintenance of cell polarity(GO:0030011) negative regulation of phosphoprotein phosphatase activity(GO:0032515) positive regulation of cell adhesion mediated by integrin(GO:0033630) CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374) |
| 0.2 | 0.9 | GO:0015712 | hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760) |
| 0.2 | 0.7 | GO:0042118 | endothelial cell activation(GO:0042118) |
| 0.2 | 0.5 | GO:0007079 | mitotic chromosome movement towards spindle pole(GO:0007079) chromosome movement towards spindle pole(GO:0051305) |
| 0.1 | 0.4 | GO:0051097 | negative regulation of helicase activity(GO:0051097) |
| 0.1 | 0.7 | GO:0032460 | negative regulation of protein oligomerization(GO:0032460) negative regulation of protein homooligomerization(GO:0032463) |
| 0.1 | 3.5 | GO:0051225 | spindle assembly(GO:0051225) |
| 0.1 | 0.6 | GO:0032203 | telomere formation via telomerase(GO:0032203) |
| 0.1 | 0.5 | GO:0042905 | 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905) |
| 0.1 | 0.9 | GO:0015937 | coenzyme A biosynthetic process(GO:0015937) |
| 0.1 | 0.8 | GO:0030277 | epithelial structure maintenance(GO:0010669) maintenance of gastrointestinal epithelium(GO:0030277) |
| 0.1 | 0.3 | GO:0006922 | obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922) |
| 0.1 | 0.5 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
| 0.1 | 0.8 | GO:0030147 | obsolete natriuresis(GO:0030147) |
| 0.1 | 0.3 | GO:0045085 | negative regulation of interleukin-2 biosynthetic process(GO:0045085) |
| 0.1 | 0.3 | GO:0017055 | negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055) |
| 0.1 | 0.5 | GO:0015862 | uridine transport(GO:0015862) |
| 0.1 | 0.8 | GO:0000381 | regulation of alternative mRNA splicing, via spliceosome(GO:0000381) |
| 0.1 | 0.4 | GO:0006883 | cellular sodium ion homeostasis(GO:0006883) |
| 0.0 | 0.1 | GO:0007538 | primary sex determination(GO:0007538) |
| 0.0 | 0.4 | GO:0050847 | progesterone receptor signaling pathway(GO:0050847) |
| 0.0 | 0.9 | GO:0006493 | protein O-linked glycosylation(GO:0006493) |
| 0.0 | 2.4 | GO:0006821 | chloride transport(GO:0006821) |
| 0.0 | 0.1 | GO:0031580 | membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580) |
| 0.0 | 0.9 | GO:0051925 | obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925) |
| 0.0 | 0.6 | GO:0051453 | regulation of intracellular pH(GO:0051453) |
| 0.0 | 2.0 | GO:0006094 | gluconeogenesis(GO:0006094) |
| 0.0 | 1.7 | GO:0071357 | response to type I interferon(GO:0034340) type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357) |
| 0.0 | 0.9 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
| 0.0 | 1.5 | GO:0007229 | integrin-mediated signaling pathway(GO:0007229) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 3.5 | GO:0070652 | HAUS complex(GO:0070652) |
| 0.3 | 2.0 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
| 0.2 | 4.3 | GO:0000178 | exosome (RNase complex)(GO:0000178) |
| 0.2 | 2.4 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.1 | 5.6 | GO:0016605 | PML body(GO:0016605) |
| 0.1 | 0.6 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
| 0.0 | 0.2 | GO:0033270 | paranode region of axon(GO:0033270) |
| 0.0 | 0.5 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
| 0.0 | 1.1 | GO:0031519 | PcG protein complex(GO:0031519) |
| 0.0 | 0.7 | GO:0034366 | spherical high-density lipoprotein particle(GO:0034366) |
| 0.0 | 0.8 | GO:0001772 | immunological synapse(GO:0001772) |
| 0.0 | 0.4 | GO:0005833 | hemoglobin complex(GO:0005833) |
| 0.0 | 2.4 | GO:0034707 | chloride channel complex(GO:0034707) |
| 0.0 | 0.9 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.0 | 1.0 | GO:0098636 | integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636) |
| 0.0 | 0.3 | GO:0031265 | CD95 death-inducing signaling complex(GO:0031265) |
| 0.0 | 0.2 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
| 0.0 | 3.3 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.0 | 1.1 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
| 0.0 | 0.7 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
| 0.0 | 2.0 | GO:0044445 | cytosolic part(GO:0044445) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.0 | 6.1 | GO:0008310 | single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310) exoribonuclease II activity(GO:0008859) |
| 1.2 | 3.7 | GO:0035403 | histone kinase activity (H3-T6 specific)(GO:0035403) |
| 1.2 | 3.7 | GO:0019976 | interleukin-2 binding(GO:0019976) |
| 0.9 | 4.6 | GO:0004126 | cytidine deaminase activity(GO:0004126) |
| 0.4 | 1.3 | GO:0035276 | ethanol binding(GO:0035276) |
| 0.3 | 2.0 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
| 0.3 | 0.9 | GO:0003829 | beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829) |
| 0.2 | 0.9 | GO:0004346 | glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309) |
| 0.2 | 0.6 | GO:0004813 | alanine-tRNA ligase activity(GO:0004813) |
| 0.2 | 0.6 | GO:0015386 | potassium:proton antiporter activity(GO:0015386) |
| 0.2 | 0.5 | GO:0043515 | kinetochore binding(GO:0043515) |
| 0.1 | 0.4 | GO:0000739 | obsolete DNA strand annealing activity(GO:0000739) |
| 0.1 | 2.3 | GO:0045028 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
| 0.1 | 2.4 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
| 0.1 | 0.6 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
| 0.1 | 0.8 | GO:0051428 | peptide hormone receptor binding(GO:0051428) |
| 0.1 | 2.8 | GO:0005159 | insulin-like growth factor receptor binding(GO:0005159) |
| 0.1 | 0.5 | GO:0004022 | alcohol dehydrogenase (NAD) activity(GO:0004022) |
| 0.1 | 0.9 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
| 0.1 | 0.4 | GO:0019871 | sodium channel inhibitor activity(GO:0019871) |
| 0.0 | 0.3 | GO:0008409 | 5'-3' exonuclease activity(GO:0008409) |
| 0.0 | 0.7 | GO:0051787 | misfolded protein binding(GO:0051787) |
| 0.0 | 0.1 | GO:0047042 | androsterone dehydrogenase (B-specific) activity(GO:0047042) indanol dehydrogenase activity(GO:0047718) |
| 0.0 | 0.4 | GO:0005344 | oxygen transporter activity(GO:0005344) |
| 0.0 | 0.8 | GO:0071855 | neuropeptide receptor binding(GO:0071855) |
| 0.0 | 1.3 | GO:0030295 | protein kinase activator activity(GO:0030295) |
| 0.0 | 0.5 | GO:0005337 | nucleoside transmembrane transporter activity(GO:0005337) |
| 0.0 | 0.5 | GO:0008536 | Ran GTPase binding(GO:0008536) |
| 0.0 | 0.1 | GO:0070643 | vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643) |
| 0.0 | 0.7 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.0 | 0.3 | GO:0051635 | obsolete bacterial cell surface binding(GO:0051635) |
| 0.0 | 0.9 | GO:0016831 | carboxy-lyase activity(GO:0016831) |
| 0.0 | 0.5 | GO:0005001 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
| 0.0 | 0.3 | GO:0042056 | chemoattractant activity(GO:0042056) |
| 0.0 | 0.4 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 0.0 | 1.6 | GO:0051082 | unfolded protein binding(GO:0051082) |
| 0.0 | 0.0 | GO:0019763 | immunoglobulin receptor activity(GO:0019763) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | SA_FAS_SIGNALING | The TNF-type receptor Fas induces apoptosis on ligand binding. |
| 0.0 | 0.4 | SA_G1_AND_S_PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
| 0.0 | 0.3 | SA_CASPASE_CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
| 0.0 | 0.9 | SIG_BCR_SIGNALING_PATHWAY | Members of the BCR signaling pathway |
