Motif ID: KLF7

Z-value: 0.431


Transcription factors associated with KLF7:

Gene SymbolEntrez IDGene Name
KLF7 ENSG00000118263.10 KLF7



Activity profile for motif KLF7.

activity profile for motif KLF7


Sorted Z-values histogram for motif KLF7

Sorted Z-values for motif KLF7



Network of associatons between targets according to the STRING database.



First level regulatory network of KLF7

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_+_96873921 0.401 ENST00000394166.3
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr19_-_39390440 0.309 ENST00000249396.7
ENST00000414941.1
ENST00000392081.2
SIRT2


sirtuin 2


chr19_-_39390350 0.288 ENST00000447739.1
ENST00000358931.5
ENST00000407552.1
SIRT2


sirtuin 2


chrX_-_92928557 0.254 ENST00000373079.3
ENST00000475430.2
NAP1L3

nucleosome assembly protein 1-like 3

chr1_-_21948906 0.178 ENST00000374761.2
ENST00000599760.1
RAP1GAP

RAP1 GTPase activating protein

chr7_+_27779714 0.174 ENST00000265393.6
ENST00000409980.1
ENST00000433216.2
ENST00000396319.2
TAX1BP1



Tax1 (human T-cell leukemia virus type I) binding protein 1



chr17_-_19281203 0.171 ENST00000487415.2
B9D1
B9 protein domain 1
chr6_+_31865552 0.166 ENST00000469372.1
ENST00000497706.1
C2

complement component 2

chr17_+_41476327 0.165 ENST00000320033.4
ARL4D
ADP-ribosylation factor-like 4D
chr1_-_19229248 0.163 ENST00000375341.3
ALDH4A1
aldehyde dehydrogenase 4 family, member A1
chr19_-_14629224 0.160 ENST00000254322.2
DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr2_-_188430478 0.158 ENST00000421427.1
TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr1_-_19229014 0.153 ENST00000538839.1
ENST00000290597.5
ALDH4A1

aldehyde dehydrogenase 4 family, member A1

chr6_-_33239612 0.151 ENST00000482399.1
ENST00000445902.2
VPS52

vacuolar protein sorting 52 homolog (S. cerevisiae)

chr5_+_141348598 0.150 ENST00000394520.2
ENST00000347642.3
RNF14

ring finger protein 14

chr6_-_33239712 0.149 ENST00000436044.2
VPS52
vacuolar protein sorting 52 homolog (S. cerevisiae)
chrX_+_102631844 0.138 ENST00000372634.1
ENST00000299872.7
NGFRAP1

nerve growth factor receptor (TNFRSF16) associated protein 1

chr19_+_39390587 0.137 ENST00000572515.1
ENST00000392079.3
ENST00000575359.1
ENST00000313582.5
NFKBIB



nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta



chr5_+_141348721 0.130 ENST00000507163.1
ENST00000394519.1
RNF14

ring finger protein 14

chr19_+_39390320 0.116 ENST00000576510.1
NFKBIB
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr6_+_30585486 0.100 ENST00000259873.4
ENST00000506373.2
MRPS18B

mitochondrial ribosomal protein S18B

chr16_+_31539183 0.084 ENST00000302312.4
AHSP
alpha hemoglobin stabilizing protein
chr3_-_33138624 0.064 ENST00000445488.2
ENST00000307377.8
ENST00000440656.1
ENST00000436768.1
ENST00000307363.5
GLB1




galactosidase, beta 1




chr16_+_31539197 0.053 ENST00000564707.1
AHSP
alpha hemoglobin stabilizing protein
chr20_+_2821340 0.047 ENST00000380445.3
ENST00000380469.3
VPS16

vacuolar protein sorting 16 homolog (S. cerevisiae)

chr1_-_21503337 0.047 ENST00000400422.1
ENST00000602326.1
ENST00000411888.1
ENST00000438975.1
EIF4G3



eukaryotic translation initiation factor 4 gamma, 3



chr17_+_38375574 0.038 ENST00000323571.4
ENST00000585043.1
ENST00000394103.3
ENST00000536600.1
WIPF2



WAS/WASL interacting protein family, member 2



chr9_+_130565487 0.035 ENST00000373225.3
ENST00000431857.1
FPGS

folylpolyglutamate synthase

chr17_+_73008755 0.034 ENST00000584208.1
ENST00000301585.5
ICT1

immature colon carcinoma transcript 1

chr9_+_130565147 0.034 ENST00000373247.2
ENST00000373245.1
ENST00000393706.2
ENST00000373228.1
FPGS



folylpolyglutamate synthase



chr8_-_6875778 0.034 ENST00000327857.2
ENST00000535841.1
DEFA3
DEFA1B
defensin, alpha 3, neutrophil-specific
defensin, alpha 1B
chr6_-_109703600 0.033 ENST00000512821.1
CD164
CD164 molecule, sialomucin
chr6_-_109703634 0.030 ENST00000324953.5
ENST00000310786.4
ENST00000275080.7
ENST00000413644.2
CD164



CD164 molecule, sialomucin



chr8_-_6837602 0.026 ENST00000382692.2
DEFA1
defensin, alpha 1
chr17_-_18218237 0.024 ENST00000542570.1
TOP3A
topoisomerase (DNA) III alpha
chr14_+_29234870 0.021 ENST00000382535.3
FOXG1
forkhead box G1
chr6_+_33239787 0.020 ENST00000439602.2
ENST00000474973.1
RPS18

ribosomal protein S18

chr19_-_7694417 0.018 ENST00000358368.4
ENST00000534844.1
XAB2

XPA binding protein 2

chr3_+_186353756 0.015 ENST00000431018.1
ENST00000450521.1
ENST00000539949.1
FETUB


fetuin B


chr13_-_108867101 0.013 ENST00000356922.4
LIG4
ligase IV, DNA, ATP-dependent
chr6_-_30585009 0.011 ENST00000376511.2
PPP1R10
protein phosphatase 1, regulatory subunit 10
chr1_-_155243235 0.006 ENST00000355560.4
ENST00000368361.4
CLK2

CDC-like kinase 2

chr1_-_157108266 0.004 ENST00000326786.4
ETV3
ets variant 3
chr22_-_30987837 0.004 ENST00000335214.6
PES1
pescadillo ribosomal biogenesis factor 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.1 0.4 GO:0009956 radial pattern formation(GO:0009956)
0.1 0.3 GO:0006562 proline catabolic process(GO:0006562)
0.0 0.2 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.3 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.2 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.3 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.0 0.1 GO:0020027 hemoglobin metabolic process(GO:0020027)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.3 GO:0005678 obsolete chromatin assembly complex(GO:0005678)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.0 0.4 GO:0003706 obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0 0.3 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.1 GO:0015925 galactosidase activity(GO:0015925)
0.0 0.0 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)