Motif ID: LEF1
Z-value: 1.425
Transcription factors associated with LEF1:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| LEF1 | ENSG00000138795.5 | LEF1 |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.3 | 4.0 | GO:0003308 | negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) |
| 0.8 | 3.4 | GO:0009956 | radial pattern formation(GO:0009956) |
| 0.5 | 2.4 | GO:0001778 | plasma membrane repair(GO:0001778) |
| 0.4 | 1.7 | GO:0048619 | embryonic hindgut morphogenesis(GO:0048619) |
| 0.4 | 1.6 | GO:0033197 | response to vitamin E(GO:0033197) |
| 0.4 | 2.3 | GO:0035414 | negative regulation of catenin import into nucleus(GO:0035414) |
| 0.3 | 1.2 | GO:0001780 | neutrophil homeostasis(GO:0001780) |
| 0.2 | 0.7 | GO:0021570 | rhombomere 4 development(GO:0021570) |
| 0.2 | 0.9 | GO:0030913 | paranodal junction assembly(GO:0030913) |
| 0.2 | 1.0 | GO:0070050 | neuron cellular homeostasis(GO:0070050) |
| 0.2 | 1.1 | GO:0016080 | synaptic vesicle targeting(GO:0016080) |
| 0.2 | 0.5 | GO:0042760 | very long-chain fatty acid catabolic process(GO:0042760) |
| 0.2 | 1.2 | GO:0032057 | negative regulation of translational initiation in response to stress(GO:0032057) |
| 0.2 | 0.5 | GO:0071504 | response to heparin(GO:0071503) cellular response to heparin(GO:0071504) |
| 0.2 | 0.5 | GO:0048319 | axial mesoderm morphogenesis(GO:0048319) |
| 0.2 | 1.8 | GO:0060351 | cartilage development involved in endochondral bone morphogenesis(GO:0060351) |
| 0.1 | 0.6 | GO:2000008 | regulation of protein localization to cell surface(GO:2000008) |
| 0.1 | 0.4 | GO:0060689 | cell differentiation involved in salivary gland development(GO:0060689) |
| 0.1 | 0.1 | GO:0034214 | protein hexamerization(GO:0034214) |
| 0.1 | 1.0 | GO:0003065 | regulation of heart rate by chemical signal(GO:0003062) positive regulation of heart rate by epinephrine(GO:0003065) |
| 0.1 | 0.2 | GO:0042701 | progesterone secretion(GO:0042701) |
| 0.1 | 0.5 | GO:0001969 | activation of membrane attack complex(GO:0001905) regulation of activation of membrane attack complex(GO:0001969) positive regulation of activation of membrane attack complex(GO:0001970) positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259) |
| 0.1 | 0.3 | GO:0042759 | fatty acid elongation, saturated fatty acid(GO:0019367) long-chain fatty acid biosynthetic process(GO:0042759) |
| 0.1 | 1.6 | GO:0034446 | substrate adhesion-dependent cell spreading(GO:0034446) |
| 0.1 | 0.4 | GO:0051013 | microtubule severing(GO:0051013) |
| 0.1 | 0.7 | GO:0006883 | cellular sodium ion homeostasis(GO:0006883) |
| 0.1 | 0.9 | GO:0031641 | regulation of myelination(GO:0031641) |
| 0.1 | 0.5 | GO:0060242 | contact inhibition(GO:0060242) |
| 0.1 | 0.3 | GO:0007028 | cytoplasm organization(GO:0007028) ribonucleoprotein complex disassembly(GO:0032988) |
| 0.1 | 0.2 | GO:0070171 | negative regulation of tooth mineralization(GO:0070171) |
| 0.1 | 1.8 | GO:0007597 | blood coagulation, intrinsic pathway(GO:0007597) |
| 0.1 | 0.3 | GO:0048170 | optic nerve morphogenesis(GO:0021631) positive regulation of long-term neuronal synaptic plasticity(GO:0048170) |
| 0.1 | 0.3 | GO:0035025 | positive regulation of Rho protein signal transduction(GO:0035025) |
| 0.1 | 0.2 | GO:0051083 | 'de novo' cotranslational protein folding(GO:0051083) |
| 0.1 | 0.4 | GO:0002051 | osteoblast fate commitment(GO:0002051) |
| 0.1 | 0.3 | GO:0006789 | bilirubin conjugation(GO:0006789) biphenyl metabolic process(GO:0018879) biphenyl catabolic process(GO:0070980) |
| 0.1 | 0.2 | GO:0007175 | negative regulation of epidermal growth factor-activated receptor activity(GO:0007175) |
| 0.1 | 0.3 | GO:0001955 | blood vessel maturation(GO:0001955) |
| 0.1 | 0.6 | GO:0051014 | actin filament severing(GO:0051014) |
| 0.1 | 0.2 | GO:0071218 | cellular response to misfolded protein(GO:0071218) |
| 0.1 | 2.0 | GO:0007026 | negative regulation of microtubule depolymerization(GO:0007026) |
| 0.1 | 1.3 | GO:0009954 | proximal/distal pattern formation(GO:0009954) |
| 0.1 | 0.1 | GO:0002378 | immunoglobulin biosynthetic process(GO:0002378) |
| 0.1 | 1.6 | GO:0036075 | endochondral ossification(GO:0001958) replacement ossification(GO:0036075) |
| 0.1 | 0.3 | GO:0048304 | positive regulation of isotype switching to IgG isotypes(GO:0048304) |
| 0.1 | 0.2 | GO:0019056 | modulation by virus of host transcription(GO:0019056) regulation of sprouting of injured axon(GO:0048686) positive regulation of sprouting of injured axon(GO:0048687) regulation of axon extension involved in regeneration(GO:0048690) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026) |
| 0.1 | 0.3 | GO:0090281 | negative regulation of neurotransmitter transport(GO:0051589) negative regulation of calcium ion import(GO:0090281) |
| 0.1 | 0.7 | GO:0042572 | retinol metabolic process(GO:0042572) |
| 0.0 | 0.4 | GO:0006654 | phosphatidic acid biosynthetic process(GO:0006654) |
| 0.0 | 0.2 | GO:0032509 | endosome transport via multivesicular body sorting pathway(GO:0032509) plasma membrane to endosome transport(GO:0048227) |
| 0.0 | 0.3 | GO:0060766 | negative regulation of androgen receptor signaling pathway(GO:0060766) |
| 0.0 | 0.8 | GO:0006957 | complement activation, alternative pathway(GO:0006957) |
| 0.0 | 0.5 | GO:0042436 | tryptophan catabolic process(GO:0006569) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218) |
| 0.0 | 1.0 | GO:0001960 | negative regulation of cytokine-mediated signaling pathway(GO:0001960) |
| 0.0 | 0.7 | GO:0030520 | intracellular estrogen receptor signaling pathway(GO:0030520) |
| 0.0 | 0.2 | GO:0006703 | estrogen biosynthetic process(GO:0006703) |
| 0.0 | 0.3 | GO:0045008 | depyrimidination(GO:0045008) |
| 0.0 | 0.2 | GO:0015871 | choline transport(GO:0015871) |
| 0.0 | 0.2 | GO:0021819 | layer formation in cerebral cortex(GO:0021819) |
| 0.0 | 1.1 | GO:0042116 | macrophage activation(GO:0042116) |
| 0.0 | 0.9 | GO:0048008 | platelet-derived growth factor receptor signaling pathway(GO:0048008) |
| 0.0 | 0.2 | GO:0021591 | ventricular system development(GO:0021591) |
| 0.0 | 0.3 | GO:0014050 | negative regulation of glutamate secretion(GO:0014050) |
| 0.0 | 1.2 | GO:0050873 | brown fat cell differentiation(GO:0050873) |
| 0.0 | 0.7 | GO:0046627 | negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077) |
| 0.0 | 0.1 | GO:0014012 | peripheral nervous system axon regeneration(GO:0014012) |
| 0.0 | 2.8 | GO:0008360 | regulation of cell shape(GO:0008360) |
| 0.0 | 0.1 | GO:0031118 | rRNA pseudouridine synthesis(GO:0031118) |
| 0.0 | 0.2 | GO:0009249 | protein lipoylation(GO:0009249) |
| 0.0 | 0.1 | GO:0048147 | negative regulation of fibroblast proliferation(GO:0048147) |
| 0.0 | 0.1 | GO:0015712 | hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760) |
| 0.0 | 0.2 | GO:0007525 | somatic muscle development(GO:0007525) |
| 0.0 | 0.5 | GO:0007413 | axonal fasciculation(GO:0007413) |
| 0.0 | 0.3 | GO:0060762 | regulation of branching involved in mammary gland duct morphogenesis(GO:0060762) |
| 0.0 | 0.4 | GO:0006198 | cAMP catabolic process(GO:0006198) |
| 0.0 | 0.1 | GO:0032927 | positive regulation of activin receptor signaling pathway(GO:0032927) |
| 0.0 | 0.6 | GO:0070534 | protein K63-linked ubiquitination(GO:0070534) |
| 0.0 | 0.3 | GO:0030212 | hyaluronan metabolic process(GO:0030212) |
| 0.0 | 0.6 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
| 0.0 | 2.2 | GO:0006921 | cellular component disassembly involved in execution phase of apoptosis(GO:0006921) execution phase of apoptosis(GO:0097194) |
| 0.0 | 0.1 | GO:0048642 | negative regulation of skeletal muscle tissue development(GO:0048642) |
| 0.0 | 0.5 | GO:0017158 | regulation of calcium ion-dependent exocytosis(GO:0017158) |
| 0.0 | 0.2 | GO:0001885 | endothelial cell development(GO:0001885) |
| 0.0 | 0.1 | GO:0015889 | cobalamin transport(GO:0015889) |
| 0.0 | 0.1 | GO:0046778 | modification by virus of host mRNA processing(GO:0046778) |
| 0.0 | 0.1 | GO:0045662 | negative regulation of myoblast differentiation(GO:0045662) |
| 0.0 | 0.1 | GO:0035058 | nonmotile primary cilium assembly(GO:0035058) |
| 0.0 | 0.2 | GO:0051205 | protein insertion into membrane(GO:0051205) |
| 0.0 | 0.2 | GO:0060765 | regulation of androgen receptor signaling pathway(GO:0060765) |
| 0.0 | 0.2 | GO:0031498 | nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986) |
| 0.0 | 0.4 | GO:0034199 | activation of protein kinase A activity(GO:0034199) |
| 0.0 | 0.1 | GO:0071569 | protein ufmylation(GO:0071569) |
| 0.0 | 0.1 | GO:0060314 | regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314) |
| 0.0 | 0.4 | GO:0048168 | regulation of neuronal synaptic plasticity(GO:0048168) |
| 0.0 | 0.1 | GO:0045329 | amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329) |
| 0.0 | 0.2 | GO:0031670 | cellular response to nutrient(GO:0031670) |
| 0.0 | 0.1 | GO:0016358 | dendrite development(GO:0016358) |
| 0.0 | 1.5 | GO:0006367 | transcription initiation from RNA polymerase II promoter(GO:0006367) |
| 0.0 | 0.1 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
| 0.0 | 0.0 | GO:0031657 | regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031657) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659) |
| 0.0 | 0.1 | GO:0070265 | necrotic cell death(GO:0070265) |
| 0.0 | 0.2 | GO:0006657 | CDP-choline pathway(GO:0006657) |
| 0.0 | 0.1 | GO:0006069 | ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069) |
| 0.0 | 0.1 | GO:0046475 | glycerophospholipid catabolic process(GO:0046475) |
| 0.0 | 0.1 | GO:0043982 | histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 1.7 | GO:0030936 | collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936) |
| 0.4 | 1.8 | GO:0033093 | Weibel-Palade body(GO:0033093) |
| 0.3 | 1.7 | GO:0070369 | beta-catenin-TCF7L2 complex(GO:0070369) beta-catenin-TCF complex(GO:1990907) |
| 0.2 | 1.4 | GO:0005587 | collagen type IV trimer(GO:0005587) |
| 0.2 | 1.8 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.1 | 1.2 | GO:0005851 | eukaryotic translation initiation factor 2B complex(GO:0005851) |
| 0.1 | 0.9 | GO:0016342 | catenin complex(GO:0016342) |
| 0.1 | 0.5 | GO:0060201 | clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201) |
| 0.1 | 1.1 | GO:0032059 | bleb(GO:0032059) |
| 0.1 | 1.2 | GO:0005606 | laminin-1 complex(GO:0005606) |
| 0.1 | 0.2 | GO:0043512 | inhibin complex(GO:0043511) inhibin A complex(GO:0043512) |
| 0.1 | 0.6 | GO:0071437 | podosome(GO:0002102) invadopodium(GO:0071437) |
| 0.0 | 0.3 | GO:0098984 | asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984) |
| 0.0 | 0.4 | GO:0005828 | kinetochore microtubule(GO:0005828) |
| 0.0 | 0.3 | GO:0000300 | obsolete peripheral to membrane of membrane fraction(GO:0000300) |
| 0.0 | 1.0 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
| 0.0 | 0.1 | GO:0014701 | junctional sarcoplasmic reticulum membrane(GO:0014701) |
| 0.0 | 1.0 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 0.0 | 1.5 | GO:0030018 | Z disc(GO:0030018) |
| 0.0 | 0.2 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
| 0.0 | 2.5 | GO:0044853 | caveola(GO:0005901) plasma membrane raft(GO:0044853) |
| 0.0 | 0.3 | GO:0031143 | pseudopodium(GO:0031143) |
| 0.0 | 0.2 | GO:0005677 | chromatin silencing complex(GO:0005677) |
| 0.0 | 2.2 | GO:0016459 | myosin complex(GO:0016459) |
| 0.0 | 0.2 | GO:0005675 | holo TFIIH complex(GO:0005675) carboxy-terminal domain protein kinase complex(GO:0032806) |
| 0.0 | 0.6 | GO:0005776 | autophagosome(GO:0005776) |
| 0.0 | 0.4 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.0 | 0.5 | GO:0009925 | basal plasma membrane(GO:0009925) |
| 0.0 | 0.8 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
| 0.0 | 0.3 | GO:0030315 | T-tubule(GO:0030315) |
| 0.0 | 0.1 | GO:0031232 | extrinsic component of external side of plasma membrane(GO:0031232) |
| 0.0 | 0.2 | GO:0031519 | PcG protein complex(GO:0031519) |
| 0.0 | 0.1 | GO:0001739 | sex chromatin(GO:0001739) |
| 0.0 | 0.2 | GO:0071778 | obsolete WINAC complex(GO:0071778) |
| 0.0 | 0.2 | GO:0030424 | axon(GO:0030424) |
| 0.0 | 5.3 | GO:0005667 | transcription factor complex(GO:0005667) |
| 0.0 | 0.6 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.0 | 0.6 | GO:0030175 | filopodium(GO:0030175) |
| 0.0 | 0.6 | GO:0043204 | perikaryon(GO:0043204) |
| 0.0 | 0.4 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 0.0 | 0.1 | GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex(GO:0005847) |
| 0.0 | 0.8 | GO:0000118 | histone deacetylase complex(GO:0000118) |
| 0.0 | 0.2 | GO:0033116 | endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116) |
| 0.0 | 0.1 | GO:0042382 | paraspeckles(GO:0042382) |
| 0.0 | 0.8 | GO:0030027 | lamellipodium(GO:0030027) |
| 0.0 | 0.5 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.0 | 0.1 | GO:0005579 | membrane attack complex(GO:0005579) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 5.3 | GO:0030547 | receptor inhibitor activity(GO:0030547) receptor antagonist activity(GO:0048019) |
| 0.4 | 1.4 | GO:0008112 | nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760) |
| 0.3 | 1.1 | GO:0001849 | complement component C1q binding(GO:0001849) |
| 0.3 | 3.6 | GO:0003706 | obsolete ligand-regulated transcription factor activity(GO:0003706) |
| 0.2 | 1.1 | GO:0042043 | neurexin family protein binding(GO:0042043) |
| 0.2 | 0.6 | GO:0016524 | latrotoxin receptor activity(GO:0016524) |
| 0.2 | 2.1 | GO:0030274 | LIM domain binding(GO:0030274) |
| 0.2 | 0.5 | GO:0004833 | tryptophan 2,3-dioxygenase activity(GO:0004833) |
| 0.2 | 0.7 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
| 0.2 | 1.3 | GO:0004522 | ribonuclease A activity(GO:0004522) |
| 0.1 | 1.3 | GO:0042153 | obsolete RPTP-like protein binding(GO:0042153) |
| 0.1 | 0.7 | GO:0005294 | neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294) |
| 0.1 | 1.4 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
| 0.1 | 1.5 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, RNA polymerase II basal transcription factor binding(GO:0001083) transcription factor activity, TFIIB-class binding(GO:0001087) RNA polymerase II basal transcription factor binding(GO:0001091) TFIIB-class transcription factor binding(GO:0001093) |
| 0.1 | 0.7 | GO:0019871 | sodium channel inhibitor activity(GO:0019871) |
| 0.1 | 0.3 | GO:0008263 | pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263) |
| 0.1 | 0.5 | GO:0031957 | very long-chain fatty acid-CoA ligase activity(GO:0031957) |
| 0.1 | 0.6 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
| 0.1 | 0.2 | GO:0048184 | obsolete follistatin binding(GO:0048184) |
| 0.1 | 1.8 | GO:0019865 | immunoglobulin binding(GO:0019865) |
| 0.1 | 0.3 | GO:0019855 | calcium channel inhibitor activity(GO:0019855) |
| 0.1 | 1.0 | GO:0042166 | acetylcholine binding(GO:0042166) |
| 0.1 | 0.9 | GO:0031369 | translation initiation factor binding(GO:0031369) |
| 0.1 | 0.4 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
| 0.1 | 0.5 | GO:0043237 | laminin-1 binding(GO:0043237) |
| 0.1 | 0.3 | GO:0009922 | fatty acid elongase activity(GO:0009922) |
| 0.1 | 1.0 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
| 0.1 | 0.6 | GO:0004157 | dihydropyrimidinase activity(GO:0004157) |
| 0.1 | 0.4 | GO:0008107 | galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127) |
| 0.1 | 1.0 | GO:0005522 | profilin binding(GO:0005522) |
| 0.1 | 0.2 | GO:0070290 | N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290) |
| 0.1 | 1.3 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
| 0.0 | 4.6 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.0 | 0.8 | GO:0043498 | obsolete cell surface binding(GO:0043498) |
| 0.0 | 0.2 | GO:0031995 | insulin-like growth factor II binding(GO:0031995) |
| 0.0 | 0.2 | GO:0015220 | choline transmembrane transporter activity(GO:0015220) |
| 0.0 | 0.3 | GO:0030172 | troponin C binding(GO:0030172) |
| 0.0 | 0.4 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 0.0 | 0.2 | GO:0048406 | nerve growth factor binding(GO:0048406) |
| 0.0 | 0.1 | GO:0019784 | NEDD8-specific protease activity(GO:0019784) |
| 0.0 | 0.1 | GO:0008336 | gamma-butyrobetaine dioxygenase activity(GO:0008336) |
| 0.0 | 1.4 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 0.0 | 0.3 | GO:0031701 | angiotensin receptor binding(GO:0031701) |
| 0.0 | 0.2 | GO:0004105 | choline-phosphate cytidylyltransferase activity(GO:0004105) |
| 0.0 | 0.1 | GO:0032795 | heterotrimeric G-protein binding(GO:0032795) |
| 0.0 | 0.2 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
| 0.0 | 0.4 | GO:0070411 | I-SMAD binding(GO:0070411) |
| 0.0 | 0.2 | GO:0034187 | obsolete apolipoprotein E binding(GO:0034187) |
| 0.0 | 0.4 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.0 | 0.1 | GO:0034711 | inhibin binding(GO:0034711) |
| 0.0 | 0.2 | GO:0001640 | adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988) |
| 0.0 | 0.2 | GO:0008889 | glycerophosphodiester phosphodiesterase activity(GO:0008889) |
| 0.0 | 0.1 | GO:0016362 | activin receptor activity, type II(GO:0016362) |
| 0.0 | 4.7 | GO:0003714 | transcription corepressor activity(GO:0003714) |
| 0.0 | 0.3 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.0 | 0.1 | GO:0004111 | creatine kinase activity(GO:0004111) |
| 0.0 | 0.5 | GO:0005242 | inward rectifier potassium channel activity(GO:0005242) |
| 0.0 | 0.1 | GO:0043208 | glycosphingolipid binding(GO:0043208) |
| 0.0 | 0.1 | GO:0047498 | calcium-dependent phospholipase A2 activity(GO:0047498) |
| 0.0 | 1.8 | GO:0031625 | ubiquitin protein ligase binding(GO:0031625) ubiquitin-like protein ligase binding(GO:0044389) |
| 0.0 | 0.1 | GO:0015562 | efflux transmembrane transporter activity(GO:0015562) |
| 0.0 | 0.1 | GO:0034481 | chondroitin sulfotransferase activity(GO:0034481) proteoglycan sulfotransferase activity(GO:0050698) |
| 0.0 | 0.3 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.0 | 0.4 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.0 | 0.2 | GO:0005123 | death receptor binding(GO:0005123) |
| 0.0 | 0.2 | GO:0005030 | neurotrophin receptor activity(GO:0005030) neurotrophin binding(GO:0043121) |
| 0.0 | 0.2 | GO:0019955 | cytokine binding(GO:0019955) |
| 0.0 | 0.7 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
| 0.0 | 0.1 | GO:0030492 | hemoglobin binding(GO:0030492) |
| 0.0 | 0.1 | GO:0004185 | serine-type carboxypeptidase activity(GO:0004185) |
| 0.0 | 0.1 | GO:0051019 | mitogen-activated protein kinase binding(GO:0051019) |
| 0.0 | 0.0 | GO:0005499 | vitamin D binding(GO:0005499) |
| 0.0 | 0.0 | GO:0030156 | benzodiazepine receptor binding(GO:0030156) |
| 0.0 | 1.2 | GO:0005178 | integrin binding(GO:0005178) |
| 0.0 | 3.1 | GO:0030528 | obsolete transcription regulator activity(GO:0030528) |
| 0.0 | 0.0 | GO:0004346 | glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309) |
| 0.0 | 0.4 | GO:0004385 | guanylate kinase activity(GO:0004385) |
| 0.0 | 0.3 | GO:0001972 | retinoic acid binding(GO:0001972) |
| 0.0 | 0.2 | GO:0030544 | Hsp70 protein binding(GO:0030544) |
| 0.0 | 0.1 | GO:0005243 | gap junction channel activity(GO:0005243) |
| 0.0 | 0.2 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
| 0.0 | 0.2 | GO:0005521 | lamin binding(GO:0005521) |
| 0.0 | 0.1 | GO:0004030 | aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030) |
| 0.0 | 0.3 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.8 | ST_WNT_BETA_CATENIN_PATHWAY | Wnt/beta-catenin Pathway |
| 0.1 | 1.6 | SA_REG_CASCADE_OF_CYCLIN_EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.1 | 0.5 | SIG_CD40PATHWAYMAP | Genes related to CD40 signaling |
| 0.0 | 0.7 | ST_GA12_PATHWAY | G alpha 12 Pathway |
