Motif ID: LMX1B_MNX1_RAX2

Z-value: 1.176

Transcription factors associated with LMX1B_MNX1_RAX2:

Gene SymbolEntrez IDGene Name
LMX1B ENSG00000136944.13 LMX1B
MNX1 ENSG00000130675.10 MNX1
RAX2 ENSG00000173976.11 RAX2






Network of associatons between targets according to the STRING database.



First level regulatory network of LMX1B_MNX1_RAX2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_169418195 4.781 ENST00000261509.6
ENST00000335742.7
PALLD

palladin, cytoskeletal associated protein

chr12_-_28123206 3.378 ENST00000542963.1
ENST00000535992.1
PTHLH

parathyroid hormone-like hormone

chr17_-_64225508 3.082 ENST00000205948.6
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr12_-_28122980 2.867 ENST00000395868.3
ENST00000534890.1
PTHLH

parathyroid hormone-like hormone

chr12_-_52967600 2.792 ENST00000549343.1
ENST00000305620.2
KRT74

keratin 74

chr7_+_134464414 2.360 ENST00000361901.2
CALD1
caldesmon 1
chr4_+_169418255 2.269 ENST00000505667.1
ENST00000511948.1
PALLD

palladin, cytoskeletal associated protein

chr3_-_151034734 2.209 ENST00000260843.4
GPR87
G protein-coupled receptor 87
chr11_-_129062093 1.967 ENST00000310343.9
ARHGAP32
Rho GTPase activating protein 32
chr7_+_134464376 1.912 ENST00000454108.1
ENST00000361675.2
CALD1

caldesmon 1

chr12_-_89746173 1.857 ENST00000308385.6
DUSP6
dual specificity phosphatase 6
chr1_-_237167718 1.804 ENST00000464121.2
MT1HL1
metallothionein 1H-like 1
chrX_-_13835147 1.608 ENST00000493677.1
ENST00000355135.2
GPM6B

glycoprotein M6B

chr7_-_107642348 1.602 ENST00000393561.1
LAMB1
laminin, beta 1
chr16_-_29910853 1.499 ENST00000308713.5
SEZ6L2
seizure related 6 homolog (mouse)-like 2
chrX_+_105937068 1.383 ENST00000324342.3
RNF128
ring finger protein 128, E3 ubiquitin protein ligase
chr19_-_51522955 1.255 ENST00000358789.3
KLK10
kallikrein-related peptidase 10
chrX_-_106243451 1.183 ENST00000355610.4
ENST00000535534.1
MORC4

MORC family CW-type zinc finger 4

chr2_+_68961934 1.107 ENST00000409202.3
ARHGAP25
Rho GTPase activating protein 25
chr2_+_68961905 1.095 ENST00000295381.3
ARHGAP25
Rho GTPase activating protein 25
chr7_-_27169801 1.086 ENST00000511914.1
HOXA4
homeobox A4
chr3_-_79816965 0.971 ENST00000464233.1
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr5_+_66300446 0.946 ENST00000261569.7
MAST4
microtubule associated serine/threonine kinase family member 4
chr4_-_143226979 0.883 ENST00000514525.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr5_+_174151536 0.858 ENST00000239243.6
ENST00000507785.1
MSX2

msh homeobox 2

chr17_-_77924627 0.832 ENST00000572862.1
ENST00000573782.1
ENST00000574427.1
ENST00000570373.1
ENST00000340848.7
ENST00000576768.1
TBC1D16





TBC1 domain family, member 16





chrX_-_10851762 0.803 ENST00000380785.1
ENST00000380787.1
MID1

midline 1 (Opitz/BBB syndrome)

chr4_-_143227088 0.793 ENST00000511838.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr18_+_29027696 0.703 ENST00000257189.4
DSG3
desmoglein 3
chr17_+_72427477 0.671 ENST00000342648.5
ENST00000481232.1
GPRC5C

G protein-coupled receptor, family C, group 5, member C

chr5_-_1882858 0.641 ENST00000511126.1
ENST00000231357.2
IRX4

iroquois homeobox 4

chr7_-_87342564 0.632 ENST00000265724.3
ENST00000416177.1
ABCB1

ATP-binding cassette, sub-family B (MDR/TAP), member 1

chr20_+_30697298 0.632 ENST00000398022.2
TM9SF4
transmembrane 9 superfamily protein member 4
chr3_+_111717600 0.623 ENST00000273368.4
TAGLN3
transgelin 3
chr2_+_187454749 0.610 ENST00000261023.3
ENST00000374907.3
ITGAV

integrin, alpha V

chr1_+_68150744 0.598 ENST00000370986.4
ENST00000370985.3
GADD45A

growth arrest and DNA-damage-inducible, alpha

chr2_+_68962014 0.586 ENST00000467265.1
ARHGAP25
Rho GTPase activating protein 25
chr8_-_18744528 0.577 ENST00000523619.1
PSD3
pleckstrin and Sec7 domain containing 3
chr3_+_111718036 0.557 ENST00000455401.2
TAGLN3
transgelin 3
chr12_+_81110684 0.546 ENST00000228644.3
MYF5
myogenic factor 5
chr8_+_105235572 0.531 ENST00000523362.1
RIMS2
regulating synaptic membrane exocytosis 2
chr2_+_234826016 0.517 ENST00000324695.4
ENST00000433712.2
TRPM8

transient receptor potential cation channel, subfamily M, member 8

chr17_+_47448102 0.514 ENST00000576461.1
RP11-81K2.1
Uncharacterized protein
chr2_-_208031943 0.514 ENST00000421199.1
ENST00000457962.1
KLF7

Kruppel-like factor 7 (ubiquitous)

chr3_-_149293990 0.492 ENST00000472417.1
WWTR1
WW domain containing transcription regulator 1
chr8_+_101170563 0.487 ENST00000520508.1
ENST00000388798.2
SPAG1

sperm associated antigen 1

chr3_+_111717511 0.477 ENST00000478951.1
ENST00000393917.2
TAGLN3

transgelin 3

chr1_+_225600404 0.471 ENST00000366845.2
AC092811.1
AC092811.1
chr4_-_186696425 0.462 ENST00000430503.1
ENST00000319454.6
ENST00000450341.1
SORBS2


sorbin and SH3 domain containing 2


chr15_+_58702742 0.455 ENST00000356113.6
ENST00000414170.3
LIPC

lipase, hepatic

chr14_+_21156915 0.451 ENST00000397990.4
ENST00000555597.1
ANG
RNASE4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr1_-_227505289 0.431 ENST00000366765.3
CDC42BPA
CDC42 binding protein kinase alpha (DMPK-like)
chr19_-_51523412 0.425 ENST00000391805.1
ENST00000599077.1
KLK10

kallikrein-related peptidase 10

chr5_+_125758865 0.424 ENST00000542322.1
ENST00000544396.1
GRAMD3

GRAM domain containing 3

chr19_-_51523275 0.418 ENST00000309958.3
KLK10
kallikrein-related peptidase 10
chr2_-_207024233 0.410 ENST00000423725.1
ENST00000233190.6
NDUFS1

NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)

chr5_+_125758813 0.389 ENST00000285689.3
ENST00000515200.1
GRAMD3

GRAM domain containing 3

chr1_-_24469602 0.377 ENST00000270800.1
IL22RA1
interleukin 22 receptor, alpha 1
chr6_-_87804815 0.376 ENST00000369582.2
CGA
glycoprotein hormones, alpha polypeptide
chr19_+_50016610 0.372 ENST00000596975.1
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr1_-_68698222 0.346 ENST00000370976.3
ENST00000354777.2
ENST00000262348.4
ENST00000540432.1
WLS



wntless Wnt ligand secretion mediator



chr1_+_180601139 0.318 ENST00000367590.4
ENST00000367589.3
XPR1

xenotropic and polytropic retrovirus receptor 1

chr3_+_111718173 0.316 ENST00000494932.1
TAGLN3
transgelin 3
chr3_+_158787041 0.310 ENST00000471575.1
ENST00000476809.1
ENST00000485419.1
IQCJ-SCHIP1


IQCJ-SCHIP1 readthrough


chr6_+_151646800 0.305 ENST00000354675.6
AKAP12
A kinase (PRKA) anchor protein 12
chr19_+_50016411 0.304 ENST00000426395.3
ENST00000600273.1
ENST00000599988.1
FCGRT


Fc fragment of IgG, receptor, transporter, alpha


chr17_-_39191107 0.299 ENST00000344363.5
KRTAP1-3
keratin associated protein 1-3
chr1_-_94586651 0.296 ENST00000535735.1
ENST00000370225.3
ABCA4

ATP-binding cassette, sub-family A (ABC1), member 4

chr18_-_33709268 0.293 ENST00000269187.5
ENST00000590986.1
ENST00000440549.2
SLC39A6


solute carrier family 39 (zinc transporter), member 6


chr1_+_214161272 0.293 ENST00000498508.2
ENST00000366958.4
PROX1

prospero homeobox 1

chr16_-_4852915 0.292 ENST00000322048.7
ROGDI
rogdi homolog (Drosophila)
chr3_-_178984759 0.290 ENST00000349697.2
ENST00000497599.1
KCNMB3

potassium large conductance calcium-activated channel, subfamily M beta member 3

chr7_-_22234381 0.287 ENST00000458533.1
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr14_-_38064198 0.287 ENST00000250448.2
FOXA1
forkhead box A1
chr1_+_214161854 0.284 ENST00000435016.1
PROX1
prospero homeobox 1
chr16_+_69345243 0.265 ENST00000254950.11
VPS4A
vacuolar protein sorting 4 homolog A (S. cerevisiae)
chr17_+_41363854 0.263 ENST00000588693.1
ENST00000588659.1
ENST00000541594.1
ENST00000536052.1
ENST00000331615.3
TMEM106A




transmembrane protein 106A




chr7_+_100136811 0.238 ENST00000300176.4
ENST00000262935.4
AGFG2

ArfGAP with FG repeats 2

chr2_+_109237717 0.227 ENST00000409441.1
LIMS1
LIM and senescent cell antigen-like domains 1
chr14_+_104182061 0.226 ENST00000216602.6
ZFYVE21
zinc finger, FYVE domain containing 21
chr7_-_107443652 0.222 ENST00000340010.5
ENST00000422236.2
ENST00000453332.1
SLC26A3


solute carrier family 26 (anion exchanger), member 3


chr2_-_216946500 0.217 ENST00000265322.7
PECR
peroxisomal trans-2-enoyl-CoA reductase
chr14_+_104182105 0.209 ENST00000311141.2
ZFYVE21
zinc finger, FYVE domain containing 21
chr7_-_143599207 0.194 ENST00000355951.2
ENST00000479870.1
ENST00000478172.1
FAM115A


family with sequence similarity 115, member A


chr15_+_93443419 0.184 ENST00000557381.1
ENST00000420239.2
CHD2

chromodomain helicase DNA binding protein 2

chr2_-_74619152 0.183 ENST00000440727.1
ENST00000409240.1
DCTN1

dynactin 1

chrX_+_78003204 0.181 ENST00000435339.3
ENST00000514744.1
LPAR4

lysophosphatidic acid receptor 4

chr2_-_207024134 0.178 ENST00000457011.1
ENST00000440274.1
ENST00000432169.1
NDUFS1


NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)


chr18_+_46065393 0.177 ENST00000256413.3
CTIF
CBP80/20-dependent translation initiation factor
chr1_+_210501589 0.177 ENST00000413764.2
ENST00000541565.1
HHAT

hedgehog acyltransferase

chr12_-_10978957 0.171 ENST00000240619.2
TAS2R10
taste receptor, type 2, member 10
chr6_-_136788001 0.166 ENST00000544465.1
MAP7
microtubule-associated protein 7
chr2_+_171034646 0.153 ENST00000409044.3
ENST00000408978.4
MYO3B

myosin IIIB

chr3_+_130569429 0.148 ENST00000505330.1
ENST00000504381.1
ENST00000507488.2
ENST00000393221.4
ATP2C1



ATPase, Ca++ transporting, type 2C, member 1



chr1_-_92952433 0.143 ENST00000294702.5
GFI1
growth factor independent 1 transcription repressor
chr4_+_69313145 0.141 ENST00000305363.4
TMPRSS11E
transmembrane protease, serine 11E
chr6_-_111927449 0.141 ENST00000368761.5
ENST00000392556.4
ENST00000340026.6
TRAF3IP2


TRAF3 interacting protein 2


chr7_+_138145076 0.140 ENST00000343526.4
TRIM24
tripartite motif containing 24
chr4_+_175204818 0.138 ENST00000503780.1
CEP44
centrosomal protein 44kDa
chr17_-_72772462 0.137 ENST00000582870.1
ENST00000581136.1
ENST00000357814.3
ENST00000579218.1
ENST00000583476.1
ENST00000580301.1
ENST00000583757.1
ENST00000582524.1
NAT9







N-acetyltransferase 9 (GCN5-related, putative)







chr11_+_63606373 0.131 ENST00000402010.2
ENST00000315032.8
ENST00000377809.4
ENST00000413835.2
ENST00000377810.3
MARK2




MAP/microtubule affinity-regulating kinase 2




chr1_+_117544366 0.131 ENST00000256652.4
ENST00000369470.1
CD101

CD101 molecule

chr7_-_83278322 0.130 ENST00000307792.3
SEMA3E
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr7_-_44580861 0.129 ENST00000546276.1
ENST00000289547.4
ENST00000381160.3
ENST00000423141.1
NPC1L1



NPC1-like 1



chr5_-_24645078 0.127 ENST00000264463.4
CDH10
cadherin 10, type 2 (T2-cadherin)
chr4_+_3388057 0.126 ENST00000538395.1
RGS12
regulator of G-protein signaling 12
chr19_-_5903714 0.126 ENST00000252675.5
ENST00000308961.4
ENST00000592634.1
ENST00000418389.2
ENST00000586349.1
ENST00000585661.1
FUT5
NDUFA11


AC024592.12

fucosyltransferase 5 (alpha (1,3) fucosyltransferase)
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa


Uncharacterized protein

chr16_+_68279207 0.126 ENST00000413021.2
ENST00000565744.1
ENST00000219345.5
PLA2G15


phospholipase A2, group XV


chr2_+_170440844 0.116 ENST00000260970.3
ENST00000433207.1
ENST00000409714.3
ENST00000462903.1
PPIG



peptidylprolyl isomerase G (cyclophilin G)



chr14_-_25479811 0.116 ENST00000550887.1
STXBP6
syntaxin binding protein 6 (amisyn)
chr4_+_71457970 0.115 ENST00000322937.6
AMBN
ameloblastin (enamel matrix protein)
chr12_+_26348582 0.114 ENST00000535504.1
SSPN
sarcospan
chr4_+_88754113 0.114 ENST00000560249.1
ENST00000540395.1
ENST00000511670.1
ENST00000361056.3
MEPE



matrix extracellular phosphoglycoprotein



chr1_-_242162375 0.114 ENST00000357246.3
MAP1LC3C
microtubule-associated protein 1 light chain 3 gamma
chr2_-_207023918 0.113 ENST00000455934.2
ENST00000449699.1
ENST00000454195.1
NDUFS1


NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)


chr2_+_177015122 0.108 ENST00000468418.3
HOXD3
homeobox D3
chr19_-_14064114 0.108 ENST00000585607.1
ENST00000538517.2
ENST00000587458.1
ENST00000538371.2
PODNL1



podocan-like 1



chr19_-_46088068 0.108 ENST00000263275.4
ENST00000323060.3
OPA3

optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)

chr1_-_68698197 0.102 ENST00000370973.2
ENST00000370971.1
WLS

wntless Wnt ligand secretion mediator

chr3_-_52090461 0.102 ENST00000296483.6
ENST00000495880.1
DUSP7

dual specificity phosphatase 7

chr19_-_36304201 0.101 ENST00000301175.3
PRODH2
proline dehydrogenase (oxidase) 2
chr12_-_118796910 0.101 ENST00000541186.1
ENST00000539872.1
TAOK3

TAO kinase 3

chr4_+_41614720 0.101 ENST00000509277.1
LIMCH1
LIM and calponin homology domains 1
chr11_+_92702886 0.100 ENST00000257068.2
ENST00000528076.1
MTNR1B

melatonin receptor 1B

chr14_+_32798547 0.100 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
AKAP6


A kinase (PRKA) anchor protein 6


chr17_-_39646116 0.099 ENST00000328119.6
KRT36
keratin 36
chr13_+_53602894 0.098 ENST00000219022.2
OLFM4
olfactomedin 4
chr4_+_71458012 0.098 ENST00000449493.2
AMBN
ameloblastin (enamel matrix protein)
chr1_+_62439037 0.096 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr6_-_136847099 0.094 ENST00000438100.2
MAP7
microtubule-associated protein 7
chr19_+_13049413 0.094 ENST00000316448.5
ENST00000588454.1
CALR

calreticulin

chr16_+_57279004 0.092 ENST00000219204.3
ARL2BP
ADP-ribosylation factor-like 2 binding protein
chr13_-_44735393 0.089 ENST00000400419.1
SMIM2
small integral membrane protein 2
chr20_-_21494654 0.089 ENST00000377142.4
NKX2-2
NK2 homeobox 2
chr13_-_95131923 0.088 ENST00000377028.5
ENST00000446125.1
DCT

dopachrome tautomerase

chr2_+_45168875 0.087 ENST00000260653.3
SIX3
SIX homeobox 3
chr1_+_154401791 0.086 ENST00000476006.1
IL6R
interleukin 6 receptor
chr12_+_4385230 0.085 ENST00000536537.1
CCND2
cyclin D2
chr2_-_190927447 0.082 ENST00000260950.4
MSTN
myostatin
chr3_-_157824292 0.082 ENST00000483851.2
SHOX2
short stature homeobox 2
chr4_-_139163491 0.080 ENST00000280612.5
SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr17_-_38859996 0.080 ENST00000264651.2
KRT24
keratin 24
chrX_-_18690210 0.080 ENST00000379984.3
RS1
retinoschisin 1
chr4_+_88754069 0.079 ENST00000395102.4
ENST00000497649.2
MEPE

matrix extracellular phosphoglycoprotein

chrX_+_135730297 0.076 ENST00000370629.2
CD40LG
CD40 ligand
chrX_+_144908928 0.075 ENST00000408967.2
TMEM257
transmembrane protein 257
chr8_+_117950422 0.075 ENST00000378279.3
AARD
alanine and arginine rich domain containing protein
chr13_-_36050819 0.075 ENST00000379919.4
MAB21L1
mab-21-like 1 (C. elegans)
chr12_-_16759711 0.075 ENST00000447609.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr14_+_72052983 0.074 ENST00000358550.2
SIPA1L1
signal-induced proliferation-associated 1 like 1
chr12_+_41831485 0.071 ENST00000539469.2
ENST00000298919.7
PDZRN4

PDZ domain containing ring finger 4

chr1_+_50569575 0.070 ENST00000371827.1
ELAVL4
ELAV like neuron-specific RNA binding protein 4
chr12_-_53994805 0.069 ENST00000328463.7
ATF7
activating transcription factor 7
chr3_-_114477787 0.068 ENST00000464560.1
ZBTB20
zinc finger and BTB domain containing 20
chr12_-_86650045 0.064 ENST00000604798.1
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chrX_-_19988382 0.063 ENST00000356980.3
ENST00000379687.3
ENST00000379682.4
CXorf23


chromosome X open reading frame 23


chr9_-_136933134 0.062 ENST00000303407.7
BRD3
bromodomain containing 3
chrX_+_107288239 0.062 ENST00000217957.5
VSIG1
V-set and immunoglobulin domain containing 1
chr8_-_25281747 0.059 ENST00000421054.2
GNRH1
gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
chr14_-_78083112 0.059 ENST00000216484.2
SPTLC2
serine palmitoyltransferase, long chain base subunit 2
chr10_+_102222798 0.057 ENST00000343737.5
WNT8B
wingless-type MMTV integration site family, member 8B
chr15_+_44092784 0.056 ENST00000458412.1
HYPK
huntingtin interacting protein K
chr6_-_31107127 0.056 ENST00000259845.4
PSORS1C2
psoriasis susceptibility 1 candidate 2
chr3_-_167191814 0.056 ENST00000466903.1
ENST00000264677.4
SERPINI2

serpin peptidase inhibitor, clade I (pancpin), member 2

chr16_+_89334512 0.055 ENST00000602042.1
AC137932.1
AC137932.1
chr8_-_93107696 0.054 ENST00000436581.2
ENST00000520583.1
ENST00000519061.1
RUNX1T1


runt-related transcription factor 1; translocated to, 1 (cyclin D-related)


chr12_+_122688090 0.053 ENST00000324189.4
ENST00000546192.1
B3GNT4

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4

chr2_-_100987007 0.051 ENST00000595083.1
AC012493.2
Uncharacterized protein
chr22_-_40929812 0.051 ENST00000422851.1
MKL1
megakaryoblastic leukemia (translocation) 1
chr12_-_86650077 0.051 ENST00000552808.2
ENST00000547225.1
MGAT4C

mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)

chr10_+_26505179 0.049 ENST00000376261.3
GAD2
glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
chr9_+_82188077 0.049 ENST00000425506.1
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr1_-_48937821 0.048 ENST00000396199.3
SPATA6
spermatogenesis associated 6
chr16_+_30669720 0.047 ENST00000356166.6
FBRS
fibrosin
chr4_+_88571429 0.046 ENST00000339673.6
ENST00000282479.7
DMP1

dentin matrix acidic phosphoprotein 1

chr6_-_167797887 0.046 ENST00000476779.2
ENST00000460930.2
ENST00000397829.4
ENST00000366827.2
TCP10



t-complex 10



chr2_+_207024306 0.046 ENST00000236957.5
ENST00000392221.1
ENST00000392222.2
ENST00000445505.1
EEF1B2



eukaryotic translation elongation factor 1 beta 2



chrX_+_135730373 0.043 ENST00000370628.2
CD40LG
CD40 ligand
chr21_-_31538971 0.042 ENST00000286808.3
CLDN17
claudin 17
chr14_+_32798462 0.040 ENST00000280979.4
AKAP6
A kinase (PRKA) anchor protein 6
chr17_-_56296580 0.039 ENST00000313863.6
ENST00000546108.1
ENST00000337050.7
ENST00000393119.2
MKS1



Meckel syndrome, type 1



chr1_-_149900122 0.037 ENST00000271628.8
SF3B4
splicing factor 3b, subunit 4, 49kDa
chr12_-_53171128 0.036 ENST00000332411.2
KRT76
keratin 76
chr4_+_41614909 0.035 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIMCH1


LIM and calponin homology domains 1


chr10_-_96829246 0.033 ENST00000371270.3
ENST00000535898.1
ENST00000539050.1
CYP2C8


cytochrome P450, family 2, subfamily C, polypeptide 8


chr1_-_48937838 0.033 ENST00000371847.3
SPATA6
spermatogenesis associated 6
chr6_+_153071925 0.032 ENST00000367244.3
ENST00000367243.3
VIP

vasoactive intestinal peptide

chr5_-_138534071 0.032 ENST00000394817.2
SIL1
SIL1 nucleotide exchange factor
chr3_+_155838337 0.031 ENST00000490337.1
ENST00000389636.5
KCNAB1

potassium voltage-gated channel, shaker-related subfamily, beta member 1

chrX_+_22050546 0.028 ENST00000379374.4
PHEX
phosphate regulating endopeptidase homolog, X-linked
chr1_-_151762943 0.027 ENST00000368825.3
ENST00000368823.1
ENST00000458431.2
ENST00000368827.6
ENST00000368824.3
TDRKH




tudor and KH domain containing




chr19_+_4402659 0.027 ENST00000301280.5
ENST00000585854.1
CHAF1A

chromatin assembly factor 1, subunit A (p150)

chr2_-_209010874 0.027 ENST00000260988.4
CRYGB
crystallin, gamma B
chr1_-_204135450 0.025 ENST00000272190.8
ENST00000367195.2
REN

renin

chr13_-_88323218 0.025 ENST00000436290.2
ENST00000453832.2
ENST00000606590.1
MIR4500HG


MIR4500 host gene (non-protein coding)


chr12_-_10955226 0.023 ENST00000240687.2
TAS2R7
taste receptor, type 2, member 7
chr4_+_88529681 0.022 ENST00000399271.1
DSPP
dentin sialophosphoprotein
chr8_-_42234745 0.022 ENST00000220812.2
DKK4
dickkopf WNT signaling pathway inhibitor 4
chr6_-_136847610 0.022 ENST00000454590.1
ENST00000432797.2
MAP7

microtubule-associated protein 7

chr10_-_115904361 0.019 ENST00000428953.1
ENST00000543782.1
C10orf118

chromosome 10 open reading frame 118


Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 6.2 GO:0060649 nipple development(GO:0060618) mammary gland bud elongation(GO:0060649) nipple morphogenesis(GO:0060658) nipple sheath formation(GO:0060659)
0.6 1.9 GO:0035987 endodermal cell fate commitment(GO:0001711) endodermal cell differentiation(GO:0035987)
0.4 3.1 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.3 1.0 GO:0021836 chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) regulation of negative chemotaxis(GO:0050923)
0.2 0.6 GO:0055005 optic placode formation involved in camera-type eye formation(GO:0046619) ventricular cardiac myofibril assembly(GO:0055005) embryonic retina morphogenesis in camera-type eye(GO:0060059) regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.2 0.6 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.1 0.9 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.1 0.4 GO:0046621 negative regulation of organ growth(GO:0046621)
0.1 1.6 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.1 0.5 GO:0050955 thermoception(GO:0050955)
0.1 0.5 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.1 0.5 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.1 0.5 GO:0042693 muscle cell fate commitment(GO:0042693)
0.1 0.3 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1 0.5 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.3 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.1 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780)
0.0 0.1 GO:1904037 positive regulation of epithelial cell apoptotic process(GO:1904037) positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 0.2 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.6 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0002384 hepatic immune response(GO:0002384)
0.0 0.1 GO:0010957 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0 0.6 GO:0071479 cellular response to ionizing radiation(GO:0071479)
0.0 0.1 GO:0043049 otic placode formation(GO:0043049)
0.0 0.1 GO:0070561 vitamin D receptor signaling pathway(GO:0070561)
0.0 0.1 GO:0014889 muscle atrophy(GO:0014889) regulation of skeletal muscle tissue growth(GO:0048631)
0.0 0.3 GO:0007603 phototransduction, visible light(GO:0007603)
0.0 0.1 GO:0032472 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) Golgi calcium ion transport(GO:0032472) manganese ion homeostasis(GO:0055071)
0.0 0.7 GO:0051881 regulation of mitochondrial membrane potential(GO:0051881)
0.0 0.3 GO:0019228 neuronal action potential(GO:0019228)
0.0 0.1 GO:0021615 glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.1 GO:0046520 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520)
0.0 0.2 GO:0008272 sulfate transport(GO:0008272)
0.0 0.1 GO:0006562 proline catabolic process(GO:0006562)
0.0 0.6 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 0.1 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.3 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.0 GO:0006540 glutamate decarboxylation to succinate(GO:0006540)
0.0 0.4 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.5 GO:0048813 dendrite morphogenesis(GO:0048813)
0.0 0.4 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0 0.1 GO:0042354 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.1 GO:0048387 protein maturation by protein folding(GO:0022417) negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.1 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0005607 laminin-2 complex(GO:0005607)
0.1 3.1 GO:0042627 chylomicron(GO:0042627)
0.1 0.3 GO:0036452 ESCRT III complex(GO:0000815) ESCRT complex(GO:0036452)
0.1 4.9 GO:0005884 actin filament(GO:0005884)
0.1 0.6 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 2.9 GO:0045095 keratin filament(GO:0045095)
0.1 0.5 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 2.0 GO:0043197 dendritic spine(GO:0043197)
0.0 0.7 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.7 GO:0030057 desmosome(GO:0030057)
0.0 4.8 GO:0005925 focal adhesion(GO:0005925)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.3 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.5 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.6 GO:0098636 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.8 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.6 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.5 GO:0030018 Z disc(GO:0030018)
0.0 0.1 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.0 0.6 GO:0042734 presynaptic membrane(GO:0042734)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 7.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.6 3.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.3 1.7 GO:0034597 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) phosphatidylinositol phosphate 4-phosphatase activity(GO:0034596) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.2 0.6 GO:0050692 DBD domain binding(GO:0050692)
0.2 0.7 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.2 0.6 GO:0042910 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.1 1.0 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 4.3 GO:0005523 tropomyosin binding(GO:0005523)
0.1 2.0 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 2.4 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.4 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.5 GO:0004522 ribonuclease A activity(GO:0004522)
0.1 0.2 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 6.2 GO:0005179 hormone activity(GO:0005179)
0.0 0.3 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.1 GO:0004607 phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.0 0.7 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.1 GO:0005174 CD40 receptor binding(GO:0005174)
0.0 0.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.4 GO:0004904 interferon receptor activity(GO:0004904)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.2 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.1 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.2 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.1 GO:0019981 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.0 0.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.3 GO:0001228 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.1 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.0 0.1 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0 0.1 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.0 0.2 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.5 GO:0070888 E-box binding(GO:0070888)
0.0 0.2 GO:0008527 taste receptor activity(GO:0008527)
0.0 1.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.2 GO:0016409 palmitoyltransferase activity(GO:0016409)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.1 GO:0034056 estrogen response element binding(GO:0034056)
0.0 5.3 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.3 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.1 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 2.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.1 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0 0.1 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.9 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway