Motif ID: MAX_TFEB
Z-value: 0.759
Transcription factors associated with MAX_TFEB:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
MAX | ENSG00000125952.14 | MAX |
TFEB | ENSG00000112561.13 | TFEB |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 2.1 | GO:0008588 | release of cytoplasmic sequestered NF-kappaB(GO:0008588) |
0.2 | 0.7 | GO:0019858 | cytosine metabolic process(GO:0019858) |
0.2 | 3.0 | GO:0048268 | negative regulation of receptor-mediated endocytosis(GO:0048261) clathrin coat assembly(GO:0048268) |
0.2 | 0.5 | GO:0010586 | miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587) |
0.2 | 0.5 | GO:0046449 | allantoin metabolic process(GO:0000255) mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338) |
0.2 | 0.5 | GO:0031118 | rRNA pseudouridine synthesis(GO:0031118) |
0.2 | 0.8 | GO:0032933 | SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501) |
0.1 | 1.0 | GO:0045176 | apical protein localization(GO:0045176) |
0.1 | 2.6 | GO:0071378 | growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378) |
0.1 | 0.4 | GO:0021570 | rhombomere 4 development(GO:0021570) facial nucleus development(GO:0021754) |
0.1 | 1.0 | GO:0071243 | uroporphyrinogen III metabolic process(GO:0046502) response to fungicide(GO:0060992) cellular response to arsenic-containing substance(GO:0071243) |
0.1 | 0.4 | GO:0009202 | purine deoxyribonucleotide biosynthetic process(GO:0009153) deoxyribonucleoside triphosphate biosynthetic process(GO:0009202) |
0.1 | 0.4 | GO:0046604 | regulation of mitotic centrosome separation(GO:0046602) positive regulation of mitotic centrosome separation(GO:0046604) |
0.1 | 0.5 | GO:0043490 | malate-aspartate shuttle(GO:0043490) |
0.1 | 0.5 | GO:0010508 | positive regulation of autophagy(GO:0010508) |
0.1 | 1.2 | GO:0007253 | cytoplasmic sequestering of NF-kappaB(GO:0007253) |
0.1 | 0.3 | GO:0032196 | transposition, DNA-mediated(GO:0006313) transposition(GO:0032196) |
0.1 | 0.4 | GO:0010944 | negative regulation of transcription by competitive promoter binding(GO:0010944) |
0.1 | 0.4 | GO:0046477 | glycosylceramide catabolic process(GO:0046477) |
0.1 | 0.3 | GO:0006419 | alanyl-tRNA aminoacylation(GO:0006419) |
0.1 | 0.4 | GO:0009698 | phenylpropanoid metabolic process(GO:0009698) coumarin metabolic process(GO:0009804) |
0.1 | 0.8 | GO:0045008 | depyrimidination(GO:0045008) |
0.1 | 0.1 | GO:0021898 | commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898) |
0.1 | 3.8 | GO:0015991 | energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662) |
0.1 | 0.3 | GO:0032929 | negative regulation of superoxide anion generation(GO:0032929) |
0.1 | 0.2 | GO:0034625 | fatty acid elongation, monounsaturated fatty acid(GO:0034625) |
0.1 | 0.6 | GO:0045039 | protein import into mitochondrial inner membrane(GO:0045039) |
0.1 | 0.3 | GO:0001575 | globoside metabolic process(GO:0001575) |
0.1 | 0.8 | GO:0000076 | DNA replication checkpoint(GO:0000076) |
0.1 | 0.3 | GO:0019348 | polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348) |
0.1 | 0.2 | GO:0006041 | glucosamine metabolic process(GO:0006041) |
0.1 | 2.0 | GO:0044349 | nucleotide-excision repair, DNA damage removal(GO:0000718) DNA excision(GO:0044349) |
0.1 | 0.2 | GO:0015670 | carbon dioxide transport(GO:0015670) |
0.1 | 0.6 | GO:0006564 | L-serine biosynthetic process(GO:0006564) |
0.1 | 1.1 | GO:0006596 | polyamine biosynthetic process(GO:0006596) |
0.1 | 0.9 | GO:0032008 | positive regulation of TOR signaling(GO:0032008) |
0.1 | 0.5 | GO:0006474 | N-terminal protein amino acid acetylation(GO:0006474) |
0.1 | 0.4 | GO:0007021 | tubulin complex assembly(GO:0007021) acetylcholine transport(GO:0015870) acetate ester transport(GO:1901374) |
0.1 | 0.2 | GO:0043457 | regulation of cellular respiration(GO:0043457) |
0.1 | 0.1 | GO:0045618 | positive regulation of keratinocyte differentiation(GO:0045618) |
0.1 | 2.6 | GO:0048146 | positive regulation of fibroblast proliferation(GO:0048146) |
0.1 | 0.4 | GO:0006452 | translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905) |
0.1 | 0.2 | GO:0045347 | negative regulation of MHC class II biosynthetic process(GO:0045347) |
0.1 | 0.2 | GO:0090467 | arginine transport(GO:0015809) L-arginine import(GO:0043091) arginine import(GO:0090467) L-arginine transport(GO:1902023) |
0.1 | 0.2 | GO:0010520 | regulation of reciprocal meiotic recombination(GO:0010520) positive regulation of meiotic nuclear division(GO:0045836) positive regulation of meiotic cell cycle(GO:0051446) regulation of meiosis I(GO:0060631) |
0.0 | 0.4 | GO:0006188 | IMP biosynthetic process(GO:0006188) IMP metabolic process(GO:0046040) |
0.0 | 0.5 | GO:0001522 | pseudouridine synthesis(GO:0001522) |
0.0 | 0.3 | GO:0060528 | secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528) |
0.0 | 0.3 | GO:1901984 | negative regulation of histone acetylation(GO:0035067) negative regulation of protein acetylation(GO:1901984) negative regulation of peptidyl-lysine acetylation(GO:2000757) |
0.0 | 0.2 | GO:0006556 | S-adenosylmethionine biosynthetic process(GO:0006556) |
0.0 | 0.2 | GO:0060649 | nipple development(GO:0060618) mammary gland bud elongation(GO:0060649) nipple morphogenesis(GO:0060658) nipple sheath formation(GO:0060659) |
0.0 | 0.1 | GO:0032227 | negative regulation of synaptic transmission, dopaminergic(GO:0032227) |
0.0 | 1.6 | GO:0016925 | protein sumoylation(GO:0016925) |
0.0 | 0.6 | GO:0097031 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
0.0 | 0.1 | GO:0002541 | activation of plasma proteins involved in acute inflammatory response(GO:0002541) |
0.0 | 0.1 | GO:0045656 | negative regulation of monocyte differentiation(GO:0045656) |
0.0 | 0.6 | GO:0006044 | N-acetylglucosamine metabolic process(GO:0006044) |
0.0 | 0.7 | GO:0048169 | regulation of long-term neuronal synaptic plasticity(GO:0048169) |
0.0 | 0.5 | GO:0055015 | ventricular cardiac muscle cell development(GO:0055015) |
0.0 | 0.2 | GO:0051988 | regulation of attachment of spindle microtubules to kinetochore(GO:0051988) |
0.0 | 0.3 | GO:0034755 | iron ion transmembrane transport(GO:0034755) |
0.0 | 0.3 | GO:0060155 | platelet dense granule organization(GO:0060155) |
0.0 | 0.6 | GO:0031115 | negative regulation of microtubule polymerization(GO:0031115) |
0.0 | 0.5 | GO:0032703 | negative regulation of interleukin-2 production(GO:0032703) |
0.0 | 1.0 | GO:0034199 | activation of protein kinase A activity(GO:0034199) |
0.0 | 0.1 | GO:0006384 | transcription initiation from RNA polymerase III promoter(GO:0006384) |
0.0 | 0.8 | GO:0035196 | production of miRNAs involved in gene silencing by miRNA(GO:0035196) |
0.0 | 0.4 | GO:0071108 | protein K48-linked deubiquitination(GO:0071108) |
0.0 | 0.7 | GO:0000380 | alternative mRNA splicing, via spliceosome(GO:0000380) |
0.0 | 0.2 | GO:0060259 | regulation of feeding behavior(GO:0060259) |
0.0 | 0.1 | GO:0018206 | peptidyl-methionine modification(GO:0018206) |
0.0 | 1.2 | GO:0006270 | DNA replication initiation(GO:0006270) |
0.0 | 0.1 | GO:0060896 | neural plate anterior/posterior regionalization(GO:0021999) neural plate pattern specification(GO:0060896) neural plate regionalization(GO:0060897) |
0.0 | 0.2 | GO:1903301 | regulation of glucokinase activity(GO:0033131) positive regulation of glucokinase activity(GO:0033133) regulation of hexokinase activity(GO:1903299) positive regulation of hexokinase activity(GO:1903301) |
0.0 | 0.2 | GO:0009143 | nucleoside triphosphate catabolic process(GO:0009143) |
0.0 | 0.1 | GO:0000491 | small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492) |
0.0 | 0.1 | GO:0070384 | Harderian gland development(GO:0070384) |
0.0 | 0.2 | GO:0015904 | tetracycline transport(GO:0015904) |
0.0 | 0.4 | GO:0046685 | response to arsenic-containing substance(GO:0046685) |
0.0 | 0.1 | GO:0072387 | flavin-containing compound biosynthetic process(GO:0042727) flavin adenine dinucleotide metabolic process(GO:0072387) |
0.0 | 0.3 | GO:0051290 | protein heterotetramerization(GO:0051290) |
0.0 | 0.7 | GO:0051865 | protein autoubiquitination(GO:0051865) |
0.0 | 0.3 | GO:0006108 | malate metabolic process(GO:0006108) |
0.0 | 0.3 | GO:0006378 | mRNA polyadenylation(GO:0006378) |
0.0 | 0.2 | GO:0022614 | membrane to membrane docking(GO:0022614) |
0.0 | 0.3 | GO:0032647 | interferon-alpha production(GO:0032607) regulation of interferon-alpha production(GO:0032647) positive regulation of interferon-alpha production(GO:0032727) |
0.0 | 0.1 | GO:0070734 | histone H3-K27 methylation(GO:0070734) |
0.0 | 0.3 | GO:0032481 | positive regulation of type I interferon production(GO:0032481) positive regulation of interferon-beta production(GO:0032728) |
0.0 | 0.2 | GO:0003310 | pancreatic A cell differentiation(GO:0003310) |
0.0 | 0.3 | GO:0098927 | early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927) |
0.0 | 0.1 | GO:0033160 | positive regulation of protein import into nucleus, translocation(GO:0033160) |
0.0 | 0.1 | GO:0035195 | gene silencing by miRNA(GO:0035195) |
0.0 | 0.2 | GO:0007080 | mitotic metaphase plate congression(GO:0007080) |
0.0 | 0.2 | GO:0006552 | leucine catabolic process(GO:0006552) |
0.0 | 0.1 | GO:0034723 | DNA replication-dependent nucleosome organization(GO:0034723) |
0.0 | 0.1 | GO:2000124 | cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926) regulation of endocannabinoid signaling pathway(GO:2000124) |
0.0 | 0.2 | GO:0045898 | regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) |
0.0 | 0.6 | GO:0000291 | nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928) |
0.0 | 0.1 | GO:0046108 | uridine metabolic process(GO:0046108) |
0.0 | 0.4 | GO:0035036 | binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036) |
0.0 | 1.0 | GO:0000289 | nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289) |
0.0 | 2.1 | GO:0006364 | rRNA processing(GO:0006364) |
0.0 | 0.2 | GO:0006020 | inositol metabolic process(GO:0006020) |
0.0 | 0.1 | GO:1901798 | positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798) |
0.0 | 0.2 | GO:0006069 | ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069) |
0.0 | 0.4 | GO:0043508 | negative regulation of JUN kinase activity(GO:0043508) |
0.0 | 0.1 | GO:0006668 | sphinganine-1-phosphate metabolic process(GO:0006668) |
0.0 | 0.3 | GO:0030500 | regulation of bone mineralization(GO:0030500) |
0.0 | 0.3 | GO:0009303 | rRNA transcription(GO:0009303) |
0.0 | 0.4 | GO:0048704 | embryonic skeletal system morphogenesis(GO:0048704) |
0.0 | 0.0 | GO:0031580 | membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580) |
0.0 | 0.2 | GO:0002566 | somatic diversification of immune receptors via somatic mutation(GO:0002566) somatic hypermutation of immunoglobulin genes(GO:0016446) |
0.0 | 0.5 | GO:0070830 | bicellular tight junction assembly(GO:0070830) |
0.0 | 0.1 | GO:0006047 | UDP-N-acetylglucosamine metabolic process(GO:0006047) |
0.0 | 1.3 | GO:0006892 | post-Golgi vesicle-mediated transport(GO:0006892) |
0.0 | 0.2 | GO:0035246 | peptidyl-arginine N-methylation(GO:0035246) |
0.0 | 1.6 | GO:0048193 | Golgi vesicle transport(GO:0048193) |
0.0 | 0.2 | GO:0006546 | glycine catabolic process(GO:0006546) |
0.0 | 0.1 | GO:0019056 | modulation by virus of host transcription(GO:0019056) regulation of sprouting of injured axon(GO:0048686) positive regulation of sprouting of injured axon(GO:0048687) regulation of axon extension involved in regeneration(GO:0048690) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026) |
0.0 | 0.3 | GO:0006400 | tRNA modification(GO:0006400) |
0.0 | 0.4 | GO:0006099 | tricarboxylic acid cycle(GO:0006099) |
0.0 | 0.1 | GO:0019985 | translesion synthesis(GO:0019985) |
0.0 | 0.1 | GO:0070171 | negative regulation of tooth mineralization(GO:0070171) |
0.0 | 0.1 | GO:0001831 | trophectodermal cellular morphogenesis(GO:0001831) |
0.0 | 0.1 | GO:0043045 | DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538) |
0.0 | 0.5 | GO:0042147 | retrograde transport, endosome to Golgi(GO:0042147) |
0.0 | 0.1 | GO:0042535 | positive regulation of tumor necrosis factor biosynthetic process(GO:0042535) |
0.0 | 0.3 | GO:0006490 | dolichol-linked oligosaccharide biosynthetic process(GO:0006488) oligosaccharide-lipid intermediate biosynthetic process(GO:0006490) |
0.0 | 0.2 | GO:0051568 | histone H3-K4 methylation(GO:0051568) |
0.0 | 0.6 | GO:0042254 | ribosome biogenesis(GO:0042254) |
0.0 | 0.2 | GO:0060351 | cartilage development involved in endochondral bone morphogenesis(GO:0060351) |
0.0 | 0.4 | GO:0048255 | RNA stabilization(GO:0043489) mRNA stabilization(GO:0048255) |
0.0 | 0.1 | GO:0015853 | adenine transport(GO:0015853) |
0.0 | 0.1 | GO:0033572 | ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512) |
0.0 | 0.3 | GO:0008333 | endosome to lysosome transport(GO:0008333) |
0.0 | 0.4 | GO:0015701 | bicarbonate transport(GO:0015701) |
0.0 | 0.1 | GO:1901343 | negative regulation of angiogenesis(GO:0016525) negative regulation of vasculature development(GO:1901343) negative regulation of blood vessel morphogenesis(GO:2000181) |
0.0 | 0.1 | GO:0007221 | positive regulation of transcription of Notch receptor target(GO:0007221) |
0.0 | 0.3 | GO:0046854 | phosphatidylinositol phosphorylation(GO:0046854) |
0.0 | 0.1 | GO:0032836 | glomerular basement membrane development(GO:0032836) |
0.0 | 0.2 | GO:0045670 | regulation of osteoclast differentiation(GO:0045670) |
0.0 | 0.1 | GO:0017183 | peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) |
0.0 | 0.2 | GO:0060216 | definitive hemopoiesis(GO:0060216) |
0.0 | 0.1 | GO:0060218 | hematopoietic stem cell differentiation(GO:0060218) |
0.0 | 0.1 | GO:0006975 | DNA damage induced protein phosphorylation(GO:0006975) |
0.0 | 0.1 | GO:0051014 | actin filament severing(GO:0051014) |
0.0 | 0.2 | GO:0006098 | pentose-phosphate shunt(GO:0006098) glyceraldehyde-3-phosphate metabolic process(GO:0019682) |
0.0 | 0.1 | GO:0000186 | activation of MAPKK activity(GO:0000186) |
0.0 | 0.1 | GO:0002724 | T cell cytokine production(GO:0002369) regulation of T cell cytokine production(GO:0002724) positive regulation of T cell cytokine production(GO:0002726) |
0.0 | 0.1 | GO:0007386 | compartment pattern specification(GO:0007386) |
0.0 | 0.2 | GO:0031397 | negative regulation of protein ubiquitination(GO:0031397) |
0.0 | 0.0 | GO:0006382 | adenosine to inosine editing(GO:0006382) |
0.0 | 0.1 | GO:0000731 | DNA synthesis involved in DNA repair(GO:0000731) |
0.0 | 0.0 | GO:0021615 | glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615) |
0.0 | 0.2 | GO:0046902 | regulation of mitochondrial membrane permeability(GO:0046902) regulation of membrane permeability(GO:0090559) |
0.0 | 0.0 | GO:0002467 | germinal center formation(GO:0002467) |
0.0 | 0.4 | GO:0006612 | protein targeting to membrane(GO:0006612) |
0.0 | 0.1 | GO:0034643 | establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497) |
0.0 | 0.0 | GO:0009174 | UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049) |
0.0 | 0.0 | GO:0010273 | regulation of oxidative phosphorylation(GO:0002082) detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169) |
0.0 | 0.7 | GO:0006369 | termination of RNA polymerase II transcription(GO:0006369) |
0.0 | 0.1 | GO:0042977 | activation of JAK2 kinase activity(GO:0042977) |
0.0 | 0.1 | GO:0048070 | regulation of developmental pigmentation(GO:0048070) |
0.0 | 0.1 | GO:0006903 | vesicle targeting(GO:0006903) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 2.1 | GO:0045323 | interleukin-1 receptor complex(GO:0045323) |
0.4 | 1.3 | GO:0030904 | retromer complex(GO:0030904) |
0.3 | 1.0 | GO:0070044 | synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044) |
0.2 | 3.0 | GO:0030122 | AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128) |
0.2 | 0.6 | GO:0000221 | vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221) |
0.2 | 0.7 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
0.2 | 1.3 | GO:0033179 | proton-transporting V-type ATPase, V0 domain(GO:0033179) |
0.1 | 1.5 | GO:0032040 | small-subunit processome(GO:0032040) |
0.1 | 1.9 | GO:0005675 | holo TFIIH complex(GO:0005675) |
0.1 | 0.1 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
0.1 | 0.2 | GO:0030688 | preribosome, small subunit precursor(GO:0030688) |
0.1 | 0.4 | GO:0031083 | BLOC complex(GO:0031082) BLOC-1 complex(GO:0031083) |
0.1 | 0.8 | GO:0042382 | paraspeckles(GO:0042382) |
0.1 | 0.4 | GO:0070695 | FHF complex(GO:0070695) |
0.1 | 2.9 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
0.1 | 0.3 | GO:0000145 | exocyst(GO:0000145) |
0.1 | 1.2 | GO:0031265 | CD95 death-inducing signaling complex(GO:0031265) |
0.1 | 0.4 | GO:0001740 | Barr body(GO:0001740) |
0.1 | 0.6 | GO:0042719 | mitochondrial intermembrane space protein transporter complex(GO:0042719) |
0.1 | 0.2 | GO:0030981 | cortical microtubule cytoskeleton(GO:0030981) |
0.1 | 2.1 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
0.1 | 0.2 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
0.1 | 0.8 | GO:0042589 | zymogen granule membrane(GO:0042589) |
0.1 | 0.7 | GO:0033180 | proton-transporting V-type ATPase, V1 domain(GO:0033180) |
0.1 | 1.3 | GO:0045263 | proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263) |
0.1 | 1.0 | GO:0061200 | clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202) |
0.1 | 0.2 | GO:0071001 | U4/U6 snRNP(GO:0071001) |
0.1 | 0.5 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
0.1 | 0.7 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
0.1 | 0.2 | GO:0000153 | cytoplasmic ubiquitin ligase complex(GO:0000153) |
0.1 | 0.7 | GO:0000808 | origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664) |
0.1 | 0.2 | GO:0009279 | cell outer membrane(GO:0009279) |
0.0 | 0.3 | GO:0008537 | proteasome activator complex(GO:0008537) |
0.0 | 0.2 | GO:0000125 | PCAF complex(GO:0000125) |
0.0 | 0.3 | GO:0030897 | HOPS complex(GO:0030897) |
0.0 | 0.2 | GO:0044295 | axonal growth cone(GO:0044295) |
0.0 | 0.4 | GO:0042555 | MCM complex(GO:0042555) |
0.0 | 0.5 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
0.0 | 0.0 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
0.0 | 0.6 | GO:0005732 | small nucleolar ribonucleoprotein complex(GO:0005732) |
0.0 | 0.6 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
0.0 | 0.4 | GO:0031254 | uropod(GO:0001931) cell trailing edge(GO:0031254) |
0.0 | 0.2 | GO:0005642 | annulate lamellae(GO:0005642) |
0.0 | 1.0 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
0.0 | 0.2 | GO:0001741 | XY body(GO:0001741) |
0.0 | 0.3 | GO:0046581 | intercellular canaliculus(GO:0046581) |
0.0 | 0.1 | GO:0070761 | pre-snoRNP complex(GO:0070761) |
0.0 | 0.9 | GO:0044665 | MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339) |
0.0 | 0.1 | GO:0071817 | MMXD complex(GO:0071817) |
0.0 | 0.1 | GO:0016533 | cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533) |
0.0 | 0.1 | GO:0071256 | Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256) |
0.0 | 0.1 | GO:0005801 | cis-Golgi network(GO:0005801) |
0.0 | 0.5 | GO:0005771 | multivesicular body(GO:0005771) |
0.0 | 0.2 | GO:0016272 | prefoldin complex(GO:0016272) |
0.0 | 0.2 | GO:0030914 | STAGA complex(GO:0030914) |
0.0 | 0.6 | GO:0001772 | immunological synapse(GO:0001772) |
0.0 | 0.1 | GO:0000127 | transcription factor TFIIIC complex(GO:0000127) |
0.0 | 0.2 | GO:0002102 | podosome(GO:0002102) |
0.0 | 0.1 | GO:0005663 | DNA replication factor C complex(GO:0005663) |
0.0 | 0.3 | GO:0045335 | phagocytic vesicle(GO:0045335) |
0.0 | 0.1 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
0.0 | 0.7 | GO:0030530 | obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530) |
0.0 | 0.1 | GO:0030681 | nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681) |
0.0 | 1.7 | GO:0005770 | late endosome(GO:0005770) |
0.0 | 0.1 | GO:0032389 | MutLalpha complex(GO:0032389) |
0.0 | 0.2 | GO:0031941 | filamentous actin(GO:0031941) |
0.0 | 0.4 | GO:0016328 | lateral plasma membrane(GO:0016328) |
0.0 | 0.1 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
0.0 | 0.2 | GO:0046930 | pore complex(GO:0046930) |
0.0 | 0.2 | GO:0044452 | nucleolar part(GO:0044452) |
0.0 | 0.1 | GO:0031233 | intrinsic component of external side of plasma membrane(GO:0031233) |
0.0 | 0.1 | GO:0016471 | vacuolar proton-transporting V-type ATPase complex(GO:0016471) proton-transporting V-type ATPase complex(GO:0033176) |
0.0 | 0.1 | GO:0071778 | obsolete WINAC complex(GO:0071778) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.7 | 3.0 | GO:0032050 | clathrin heavy chain binding(GO:0032050) |
0.4 | 2.5 | GO:0008269 | JAK pathway signal transduction adaptor activity(GO:0008269) |
0.3 | 1.0 | GO:0004853 | uroporphyrinogen decarboxylase activity(GO:0004853) |
0.3 | 0.8 | GO:0008263 | pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263) |
0.2 | 2.1 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
0.2 | 0.5 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
0.2 | 0.8 | GO:0004647 | phosphoserine phosphatase activity(GO:0004647) |
0.1 | 0.4 | GO:0004730 | pseudouridylate synthase activity(GO:0004730) |
0.1 | 2.9 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
0.1 | 0.3 | GO:0004809 | tRNA (guanine-N2-)-methyltransferase activity(GO:0004809) |
0.1 | 0.5 | GO:0015183 | L-aspartate transmembrane transporter activity(GO:0015183) |
0.1 | 0.2 | GO:0008493 | tetracycline transporter activity(GO:0008493) |
0.1 | 0.4 | GO:0015925 | galactosidase activity(GO:0015925) |
0.1 | 0.3 | GO:0004813 | alanine-tRNA ligase activity(GO:0004813) |
0.1 | 0.8 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
0.1 | 0.3 | GO:0030060 | L-malate dehydrogenase activity(GO:0030060) |
0.1 | 0.2 | GO:0032552 | deoxyribonucleotide binding(GO:0032552) |
0.1 | 0.5 | GO:0008853 | exodeoxyribonuclease III activity(GO:0008853) |
0.1 | 0.3 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
0.1 | 2.0 | GO:0051059 | NF-kappaB binding(GO:0051059) |
0.1 | 0.4 | GO:0042392 | sphingosine-1-phosphate phosphatase activity(GO:0042392) |
0.1 | 0.3 | GO:0004803 | transposase activity(GO:0004803) |
0.1 | 0.9 | GO:0000339 | RNA cap binding(GO:0000339) |
0.1 | 0.5 | GO:0019826 | oxygen sensor activity(GO:0019826) |
0.1 | 1.6 | GO:0019003 | GDP binding(GO:0019003) |
0.1 | 1.8 | GO:0097472 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472) |
0.1 | 0.2 | GO:0047179 | platelet-activating factor acetyltransferase activity(GO:0047179) |
0.1 | 0.2 | GO:0032038 | myosin II heavy chain binding(GO:0032038) |
0.0 | 0.5 | GO:0030515 | snoRNA binding(GO:0030515) |
0.0 | 0.5 | GO:0003688 | DNA replication origin binding(GO:0003688) |
0.0 | 0.2 | GO:0009922 | fatty acid elongase activity(GO:0009922) |
0.0 | 0.2 | GO:0004727 | prenylated protein tyrosine phosphatase activity(GO:0004727) |
0.0 | 0.2 | GO:0034701 | tripeptidase activity(GO:0034701) |
0.0 | 0.3 | GO:0004430 | 1-phosphatidylinositol 4-kinase activity(GO:0004430) |
0.0 | 0.3 | GO:0042609 | CD4 receptor binding(GO:0042609) |
0.0 | 0.4 | GO:0016018 | cyclosporin A binding(GO:0016018) |
0.0 | 0.2 | GO:0035242 | protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242) |
0.0 | 0.3 | GO:0005381 | iron ion transmembrane transporter activity(GO:0005381) |
0.0 | 0.3 | GO:0008159 | obsolete positive transcription elongation factor activity(GO:0008159) |
0.0 | 0.3 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
0.0 | 0.2 | GO:0000827 | inositol-1,3,4,5,6-pentakisphosphate kinase activity(GO:0000827) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857) |
0.0 | 0.2 | GO:0004024 | alcohol dehydrogenase activity, zinc-dependent(GO:0004024) |
0.0 | 1.0 | GO:0044769 | ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) |
0.0 | 0.1 | GO:0008192 | RNA guanylyltransferase activity(GO:0008192) |
0.0 | 0.4 | GO:0042826 | histone deacetylase binding(GO:0042826) |
0.0 | 0.5 | GO:0031369 | translation initiation factor binding(GO:0031369) |
0.0 | 0.1 | GO:0016534 | cyclin-dependent protein kinase 5 activator activity(GO:0016534) |
0.0 | 0.2 | GO:0004766 | spermidine synthase activity(GO:0004766) |
0.0 | 2.9 | GO:0015078 | hydrogen ion transmembrane transporter activity(GO:0015078) |
0.0 | 0.1 | GO:0004666 | prostaglandin-endoperoxide synthase activity(GO:0004666) |
0.0 | 2.6 | GO:0008080 | N-acetyltransferase activity(GO:0008080) |
0.0 | 1.0 | GO:0030552 | cAMP binding(GO:0030552) |
0.0 | 0.1 | GO:0004348 | glucosylceramidase activity(GO:0004348) |
0.0 | 0.2 | GO:0004616 | phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616) |
0.0 | 0.2 | GO:0019238 | cyclohydrolase activity(GO:0019238) |
0.0 | 0.2 | GO:0005220 | inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220) |
0.0 | 0.7 | GO:0043022 | ribosome binding(GO:0043022) |
0.0 | 0.2 | GO:0004485 | methylcrotonoyl-CoA carboxylase activity(GO:0004485) |
0.0 | 0.2 | GO:0048256 | flap endonuclease activity(GO:0048256) |
0.0 | 1.0 | GO:0019905 | syntaxin binding(GO:0019905) |
0.0 | 0.5 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
0.0 | 0.5 | GO:0004004 | ATP-dependent RNA helicase activity(GO:0004004) |
0.0 | 0.1 | GO:0046976 | histone methyltransferase activity (H3-K27 specific)(GO:0046976) |
0.0 | 0.4 | GO:0019206 | nucleoside kinase activity(GO:0019206) |
0.0 | 0.3 | GO:0015355 | secondary active monocarboxylate transmembrane transporter activity(GO:0015355) |
0.0 | 0.1 | GO:0000247 | C-8 sterol isomerase activity(GO:0000247) |
0.0 | 0.1 | GO:0043008 | ATP-dependent protein binding(GO:0043008) |
0.0 | 0.1 | GO:0004850 | uridine phosphorylase activity(GO:0004850) |
0.0 | 0.1 | GO:0005345 | purine nucleobase transmembrane transporter activity(GO:0005345) |
0.0 | 0.6 | GO:0004708 | MAP kinase kinase activity(GO:0004708) |
0.0 | 0.1 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
0.0 | 0.7 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
0.0 | 0.2 | GO:0004047 | aminomethyltransferase activity(GO:0004047) |
0.0 | 1.0 | GO:0003899 | DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062) |
0.0 | 0.1 | GO:0003689 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
0.0 | 0.4 | GO:0042162 | telomeric DNA binding(GO:0042162) |
0.0 | 0.1 | GO:0008384 | IkappaB kinase activity(GO:0008384) |
0.0 | 0.2 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
0.0 | 0.4 | GO:0008408 | 3'-5' exonuclease activity(GO:0008408) |
0.0 | 0.1 | GO:0004925 | prolactin receptor activity(GO:0004925) |
0.0 | 0.3 | GO:0042288 | MHC class I protein binding(GO:0042288) |
0.0 | 0.2 | GO:0061659 | ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659) |
0.0 | 0.2 | GO:0015288 | porin activity(GO:0015288) |
0.0 | 0.4 | GO:0005095 | GTPase inhibitor activity(GO:0005095) |
0.0 | 0.5 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
0.0 | 0.8 | GO:0016831 | carboxy-lyase activity(GO:0016831) |
0.0 | 0.1 | GO:0032138 | single base insertion or deletion binding(GO:0032138) |
0.0 | 0.3 | GO:0004190 | aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001) |
0.0 | 0.5 | GO:0008656 | cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656) |
0.0 | 0.2 | GO:0016861 | intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861) |
0.0 | 0.0 | GO:0016309 | 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309) |
0.0 | 0.1 | GO:0015165 | pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165) |
0.0 | 0.3 | GO:0016780 | phosphotransferase activity, for other substituted phosphate groups(GO:0016780) |
0.0 | 0.4 | GO:0005246 | calcium channel regulator activity(GO:0005246) |
0.0 | 0.1 | GO:0004046 | aminoacylase activity(GO:0004046) |
0.0 | 0.2 | GO:0015125 | bile acid transmembrane transporter activity(GO:0015125) |
0.0 | 0.0 | GO:0005047 | signal recognition particle binding(GO:0005047) |
0.0 | 0.6 | GO:0048306 | calcium-dependent protein binding(GO:0048306) |
0.0 | 0.3 | GO:0003746 | translation elongation factor activity(GO:0003746) |
0.0 | 0.1 | GO:0008428 | ribonuclease inhibitor activity(GO:0008428) |
0.0 | 0.2 | GO:0017137 | Rab GTPase binding(GO:0017137) |
0.0 | 0.1 | GO:0008517 | folic acid transporter activity(GO:0008517) |
0.0 | 0.2 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
0.0 | 0.4 | GO:0004385 | guanylate kinase activity(GO:0004385) |
0.0 | 0.5 | GO:0002039 | p53 binding(GO:0002039) |
0.0 | 0.4 | GO:0005452 | inorganic anion exchanger activity(GO:0005452) |
0.0 | 0.0 | GO:0033829 | O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829) |
0.0 | 0.0 | GO:0000033 | alpha-1,3-mannosyltransferase activity(GO:0000033) |
0.0 | 0.3 | GO:0001085 | RNA polymerase II transcription factor binding(GO:0001085) |
0.0 | 0.1 | GO:0070087 | chromo shadow domain binding(GO:0070087) |
0.0 | 0.0 | GO:0001849 | complement component C1q binding(GO:0001849) |
0.0 | 0.2 | GO:0005372 | water transmembrane transporter activity(GO:0005372) water channel activity(GO:0015250) |
0.0 | 0.1 | GO:0004176 | ATP-dependent peptidase activity(GO:0004176) |
0.0 | 0.0 | GO:0005324 | long-chain fatty acid transporter activity(GO:0005324) |
0.0 | 0.0 | GO:0070097 | delta-catenin binding(GO:0070097) |
0.0 | 0.1 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
0.0 | 0.1 | GO:0017069 | snRNA binding(GO:0017069) |
0.0 | 0.1 | GO:0004550 | nucleoside diphosphate kinase activity(GO:0004550) |
0.0 | 0.0 | GO:0000403 | four-way junction DNA binding(GO:0000400) Y-form DNA binding(GO:0000403) |
0.0 | 0.3 | GO:0005504 | fatty acid binding(GO:0005504) |
0.0 | 0.1 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
0.0 | 0.0 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
0.0 | 2.6 | GO:0003924 | GTPase activity(GO:0003924) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 2.2 | SA_REG_CASCADE_OF_CYCLIN_EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
0.0 | 0.7 | ST_G_ALPHA_S_PATHWAY | G alpha s Pathway |
0.0 | 0.9 | ST_P38_MAPK_PATHWAY | p38 MAPK Pathway |