Motif ID: MAX_TFEB

Z-value: 0.759

Transcription factors associated with MAX_TFEB:

Gene SymbolEntrez IDGene Name
MAX ENSG00000125952.14 MAX
TFEB ENSG00000112561.13 TFEB






Network of associatons between targets according to the STRING database.



First level regulatory network of MAX_TFEB

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_100464760 2.120 ENST00000200457.4
TRIP6
thyroid hormone receptor interactor 6
chrX_+_102469997 1.344 ENST00000372695.5
ENST00000372691.3
BEX4

brain expressed, X-linked 4

chr12_-_58146048 1.275 ENST00000547281.1
ENST00000546489.1
ENST00000552388.1
ENST00000540325.1
ENST00000312990.6
CDK4




cyclin-dependent kinase 4




chr12_+_93964158 1.271 ENST00000549206.1
SOCS2
suppressor of cytokine signaling 2
chr18_+_9708162 1.245 ENST00000578921.1
RAB31
RAB31, member RAS oncogene family
chr12_+_93964746 1.228 ENST00000536696.2
SOCS2
suppressor of cytokine signaling 2
chr11_-_85779786 1.219 ENST00000356360.5
PICALM
phosphatidylinositol binding clathrin assembly protein
chr7_+_106685079 1.157 ENST00000265717.4
PRKAR2B
protein kinase, cAMP-dependent, regulatory, type II, beta
chr11_+_18343800 1.153 ENST00000453096.2
GTF2H1
general transcription factor IIH, polypeptide 1, 62kDa
chr12_-_58146128 1.119 ENST00000551800.1
ENST00000549606.1
ENST00000257904.6
CDK4


cyclin-dependent kinase 4


chr1_+_44440575 1.045 ENST00000532642.1
ENST00000236067.4
ENST00000471859.2
ATP6V0B


ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b


chr19_-_48018203 1.034 ENST00000595227.1
ENST00000593761.1
ENST00000263354.3
NAPA


N-ethylmaleimide-sensitive factor attachment protein, alpha


chr13_+_113951607 0.997 ENST00000397181.3
LAMP1
lysosomal-associated membrane protein 1
chr12_+_28343365 0.940 ENST00000545336.1
CCDC91
coiled-coil domain containing 91
chr4_-_47465666 0.869 ENST00000381571.4
COMMD8
COMM domain containing 8
chr15_-_83316254 0.846 ENST00000567678.1
ENST00000450751.2
CPEB1

cytoplasmic polyadenylation element binding protein 1

chr4_-_99850243 0.826 ENST00000280892.6
ENST00000511644.1
ENST00000504432.1
ENST00000505992.1
EIF4E



eukaryotic translation initiation factor 4E



chr11_+_18344106 0.804 ENST00000534641.1
ENST00000525831.1
ENST00000265963.4
GTF2H1


general transcription factor IIH, polypeptide 1, 62kDa


chr19_+_1275917 0.792 ENST00000469144.1
C19orf24
chromosome 19 open reading frame 24
chr7_+_155090271 0.781 ENST00000476756.1
INSIG1
insulin induced gene 1
chr11_-_85779971 0.768 ENST00000393346.3
PICALM
phosphatidylinositol binding clathrin assembly protein
chr21_-_46237883 0.744 ENST00000397893.3
SUMO3
small ubiquitin-like modifier 3
chr6_-_33385823 0.709 ENST00000494751.1
ENST00000374496.3
CUTA

cutA divalent cation tolerance homolog (E. coli)

chr10_+_70883908 0.686 ENST00000263559.6
ENST00000395098.1
ENST00000546041.1
ENST00000541711.1
VPS26A



vacuolar protein sorting 26 homolog A (S. pombe)



chr6_-_33385854 0.678 ENST00000488478.1
CUTA
cutA divalent cation tolerance homolog (E. coli)
chr19_+_10765003 0.677 ENST00000407004.3
ENST00000589998.1
ENST00000589600.1
ILF3


interleukin enhancer binding factor 3, 90kDa


chr2_-_10587897 0.669 ENST00000405333.1
ENST00000443218.1
ODC1

ornithine decarboxylase 1

chr17_-_46688334 0.657 ENST00000239165.7
HOXB7
homeobox B7
chr16_+_2570340 0.646 ENST00000568263.1
ENST00000293971.6
ENST00000302956.4
ENST00000413459.3
ENST00000566706.1
ENST00000569879.1
AMDHD2





amidohydrolase domain containing 2





chr15_-_83316087 0.646 ENST00000568757.1
CPEB1
cytoplasmic polyadenylation element binding protein 1
chr6_-_33385655 0.635 ENST00000440279.3
ENST00000607266.1
CUTA

cutA divalent cation tolerance homolog (E. coli)

chr11_-_122931881 0.634 ENST00000526110.1
ENST00000227378.3
HSPA8

heat shock 70kDa protein 8

chr1_-_51425902 0.629 ENST00000396153.2
FAF1
Fas (TNFRSF6) associated factor 1
chr1_-_28559502 0.618 ENST00000263697.4
DNAJC8
DnaJ (Hsp40) homolog, subfamily C, member 8
chr3_+_158519654 0.608 ENST00000415822.2
ENST00000392813.4
ENST00000264266.8
MFSD1


major facilitator superfamily domain containing 1


chr11_-_85780086 0.605 ENST00000532317.1
ENST00000528256.1
ENST00000526033.1
PICALM


phosphatidylinositol binding clathrin assembly protein


chr14_-_20923195 0.605 ENST00000206542.4
OSGEP
O-sialoglycoprotein endopeptidase
chr10_+_5488564 0.601 ENST00000449083.1
ENST00000380359.3
NET1

neuroepithelial cell transforming 1

chr1_+_154193325 0.594 ENST00000428931.1
ENST00000441890.1
ENST00000271877.7
ENST00000412596.1
ENST00000368504.1
ENST00000437652.1
UBAP2L





ubiquitin associated protein 2-like





chr1_+_45477901 0.582 ENST00000434478.1
UROD
uroporphyrinogen decarboxylase
chr6_-_97345689 0.577 ENST00000316149.7
NDUFAF4
NADH dehydrogenase (ubiquinone) complex I, assembly factor 4
chr11_+_63706444 0.576 ENST00000377793.4
ENST00000456907.2
ENST00000539656.1
NAA40


N(alpha)-acetyltransferase 40, NatD catalytic subunit


chr3_+_50654550 0.572 ENST00000430409.1
ENST00000357955.2
MAPKAPK3

mitogen-activated protein kinase-activated protein kinase 3

chrX_+_16804544 0.570 ENST00000380122.5
ENST00000398155.4
TXLNG

taxilin gamma

chr6_-_43197189 0.563 ENST00000509253.1
ENST00000393987.2
ENST00000230431.6
DNPH1


2'-deoxynucleoside 5'-phosphate N-hydrolase 1


chr8_+_98656336 0.562 ENST00000336273.3
MTDH
metadherin
chr22_+_21996549 0.561 ENST00000248958.4
SDF2L1
stromal cell-derived factor 2-like 1
chr1_-_51425772 0.541 ENST00000371778.4
FAF1
Fas (TNFRSF6) associated factor 1
chr6_-_144329531 0.541 ENST00000429150.1
ENST00000392309.1
ENST00000416623.1
ENST00000392307.1
PLAGL1



pleiomorphic adenoma gene-like 1



chr19_+_8509842 0.537 ENST00000325495.4
ENST00000600092.1
ENST00000594907.1
ENST00000596984.1
ENST00000601645.1
HNRNPM




heterogeneous nuclear ribonucleoprotein M




chr1_-_183604794 0.515 ENST00000367534.1
ENST00000359856.6
ENST00000294742.6
ARPC5


actin related protein 2/3 complex, subunit 5, 16kDa


chr2_-_220118631 0.515 ENST00000248437.4
TUBA4A
tubulin, alpha 4a
chr17_+_40440481 0.512 ENST00000590726.2
ENST00000452307.2
ENST00000444283.1
ENST00000588868.1
STAT5A



signal transducer and activator of transcription 5A



chr8_+_98788003 0.503 ENST00000521545.2
LAPTM4B
lysosomal protein transmembrane 4 beta
chr3_-_113465065 0.501 ENST00000497255.1
ENST00000478020.1
ENST00000240922.3
ENST00000493900.1
NAA50



N(alpha)-acetyltransferase 50, NatE catalytic subunit



chrX_+_100663243 0.495 ENST00000316594.5
HNRNPH2
heterogeneous nuclear ribonucleoprotein H2 (H')
chr16_+_2867164 0.471 ENST00000455114.1
ENST00000450020.3
PRSS21

protease, serine, 21 (testisin)

chr11_+_67159416 0.470 ENST00000307980.2
ENST00000544620.1
RAD9A

RAD9 homolog A (S. pombe)

chr6_+_125524785 0.462 ENST00000392482.2
TPD52L1
tumor protein D52-like 1
chr16_+_2867228 0.459 ENST00000005995.3
ENST00000574813.1
PRSS21

protease, serine, 21 (testisin)

chr21_-_46238034 0.458 ENST00000332859.6
SUMO3
small ubiquitin-like modifier 3
chr1_+_38478378 0.452 ENST00000373014.4
UTP11L
UTP11-like, U3 small nucleolar ribonucleoprotein, (yeast)
chr2_-_220042825 0.449 ENST00000409789.1
CNPPD1
cyclin Pas1/PHO80 domain containing 1
chr6_+_36562132 0.445 ENST00000373715.6
ENST00000339436.7
SRSF3

serine/arginine-rich splicing factor 3

chr1_-_39325431 0.444 ENST00000373001.3
RRAGC
Ras-related GTP binding C
chr2_-_120980939 0.443 ENST00000426077.2
TMEM185B
transmembrane protein 185B
chr3_+_19988885 0.442 ENST00000422242.1
RAB5A
RAB5A, member RAS oncogene family
chr11_+_65479702 0.432 ENST00000530446.1
ENST00000534104.1
ENST00000530605.1
ENST00000528198.1
ENST00000531880.1
ENST00000534650.1
KAT5





K(lysine) acetyltransferase 5





chr12_-_121342170 0.422 ENST00000353487.2
SPPL3
signal peptide peptidase like 3
chr17_+_46970134 0.419 ENST00000503641.1
ENST00000514808.1
ATP5G1

ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)

chr19_+_5681153 0.419 ENST00000577222.1
ENST00000579559.1
RPL36
HSD11B1L
ribosomal protein L36
hydroxysteroid (11-beta) dehydrogenase 1-like
chr7_-_27135591 0.414 ENST00000343060.4
ENST00000355633.5
HOXA1

homeobox A1

chr5_+_122110691 0.414 ENST00000379516.2
ENST00000505934.1
ENST00000514949.1
SNX2


sorting nexin 2


chr6_-_33385870 0.410 ENST00000488034.1
CUTA
cutA divalent cation tolerance homolog (E. coli)
chrX_-_100662881 0.409 ENST00000218516.3
GLA
galactosidase, alpha
chr11_-_57194418 0.408 ENST00000395123.2
ENST00000530005.1
ENST00000532278.1
SLC43A3


solute carrier family 43, member 3


chr6_-_33385902 0.405 ENST00000374500.5
CUTA
cutA divalent cation tolerance homolog (E. coli)
chr7_-_99699538 0.405 ENST00000343023.6
ENST00000303887.5
MCM7

minichromosome maintenance complex component 7

chr9_-_103115185 0.400 ENST00000374902.4
TEX10
testis expressed 10
chr16_-_1401799 0.397 ENST00000007390.2
TSR3
TSR3, 20S rRNA accumulation, homolog (S. cerevisiae)
chr7_-_56119156 0.396 ENST00000421312.1
ENST00000416592.1
PSPH

phosphoserine phosphatase

chr2_+_234668894 0.394 ENST00000608383.1
ENST00000360418.3
ENST00000305208.5
UGT1A1

UGT1A8
UDP glucuronosyltransferase 1 family, polypeptide A8

UDP glucuronosyltransferase 1 family, polypeptide A1
chr1_+_152486950 0.390 ENST00000368790.3
CRCT1
cysteine-rich C-terminal 1
chr19_-_12886327 0.387 ENST00000397668.3
ENST00000587178.1
ENST00000264827.5
HOOK2


hook microtubule-tethering protein 2


chr4_-_100871506 0.387 ENST00000296417.5
H2AFZ
H2A histone family, member Z
chr3_+_19988566 0.386 ENST00000273047.4
RAB5A
RAB5A, member RAS oncogene family
chr7_-_56118981 0.386 ENST00000419984.2
ENST00000413218.1
ENST00000424596.1
PSPH


phosphoserine phosphatase


chr17_+_46970127 0.385 ENST00000355938.5
ATP5G1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chrX_-_100604184 0.384 ENST00000372902.3
TIMM8A
translocase of inner mitochondrial membrane 8 homolog A (yeast)
chr17_+_46970178 0.384 ENST00000393366.2
ENST00000506855.1
ATP5G1

ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)

chr1_+_38478432 0.378 ENST00000537711.1
UTP11L
UTP11-like, U3 small nucleolar ribonucleoprotein, (yeast)
chr1_+_45477819 0.375 ENST00000246337.4
UROD
uroporphyrinogen decarboxylase
chr5_+_43603229 0.371 ENST00000344920.4
ENST00000512996.2
NNT

nicotinamide nucleotide transhydrogenase

chr1_-_222885770 0.371 ENST00000355727.2
ENST00000340020.6
AIDA

axin interactor, dorsalization associated

chrX_+_129040122 0.368 ENST00000394422.3
ENST00000371051.5
UTP14A

UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)

chr1_-_207226313 0.366 ENST00000367084.1
YOD1
YOD1 deubiquitinase
chr8_+_133787586 0.365 ENST00000395379.1
ENST00000395386.2
ENST00000337920.4
PHF20L1


PHD finger protein 20-like 1


chrX_+_41192595 0.364 ENST00000399959.2
DDX3X
DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
chr22_-_22221658 0.363 ENST00000544786.1
MAPK1
mitogen-activated protein kinase 1
chr9_+_74526384 0.362 ENST00000334731.2
ENST00000377031.3
C9orf85

chromosome 9 open reading frame 85

chr19_+_12848299 0.362 ENST00000357332.3
ASNA1
arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)
chr19_-_46974664 0.359 ENST00000438932.2
PNMAL1
paraneoplastic Ma antigen family-like 1
chr7_+_150759634 0.359 ENST00000392826.2
ENST00000461735.1
SLC4A2

solute carrier family 4 (anion exchanger), member 2

chr11_-_85780853 0.359 ENST00000531930.1
ENST00000528398.1
PICALM

phosphatidylinositol binding clathrin assembly protein

chr6_-_31763721 0.355 ENST00000375663.3
VARS
valyl-tRNA synthetase
chr21_-_46237959 0.355 ENST00000397898.3
ENST00000411651.2
SUMO3

small ubiquitin-like modifier 3

chr8_-_54755459 0.355 ENST00000524234.1
ENST00000521275.1
ENST00000396774.2
ATP6V1H


ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H


chr7_+_16793160 0.352 ENST00000262067.4
TSPAN13
tetraspanin 13
chr1_-_78149041 0.352 ENST00000414381.1
ENST00000370798.1
ZZZ3

zinc finger, ZZ-type containing 3

chr4_-_76439483 0.351 ENST00000380840.2
ENST00000513257.1
ENST00000507014.1
RCHY1


ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase


chr22_-_22221900 0.349 ENST00000215832.6
ENST00000398822.3
MAPK1

mitogen-activated protein kinase 1

chr4_-_83295103 0.349 ENST00000313899.7
ENST00000352301.4
ENST00000509107.1
ENST00000353341.4
ENST00000541060.1
HNRNPD




heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)




chr18_+_21083437 0.347 ENST00000269221.3
ENST00000590868.1
ENST00000592119.1
C18orf8


chromosome 18 open reading frame 8


chrX_+_129040094 0.346 ENST00000425117.2
UTP14A
UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
chr16_-_57219966 0.346 ENST00000565760.1
ENST00000309137.8
ENST00000570184.1
ENST00000562324.1
FAM192A



family with sequence similarity 192, member A



chr4_+_79697495 0.342 ENST00000502871.1
ENST00000335016.5
BMP2K

BMP2 inducible kinase

chr16_+_88923494 0.342 ENST00000567895.1
ENST00000301021.3
ENST00000565504.1
ENST00000567312.1
ENST00000568583.1
ENST00000561840.1
TRAPPC2L





trafficking protein particle complex 2-like





chr11_-_57194218 0.340 ENST00000529554.1
SLC43A3
solute carrier family 43, member 3
chr7_+_12726474 0.339 ENST00000396662.1
ENST00000356797.3
ENST00000396664.2
ARL4A


ADP-ribosylation factor-like 4A


chr19_-_46974741 0.336 ENST00000313683.10
ENST00000602246.1
PNMAL1

paraneoplastic Ma antigen family-like 1

chr12_+_53645870 0.332 ENST00000329548.4
MFSD5
major facilitator superfamily domain containing 5
chr19_+_7587491 0.327 ENST00000264079.6
MCOLN1
mucolipin 1
chr2_-_47572105 0.323 ENST00000419035.1
ENST00000448713.1
ENST00000450550.1
ENST00000413185.2
AC073283.4



AC073283.4



chr11_-_122932730 0.321 ENST00000532182.1
ENST00000524590.1
ENST00000528292.1
ENST00000533540.1
ENST00000525463.1
HSPA8




heat shock 70kDa protein 8




chr4_+_56719782 0.319 ENST00000381295.2
ENST00000346134.7
ENST00000349598.6
EXOC1


exocyst complex component 1


chrX_+_8433376 0.315 ENST00000440654.2
ENST00000381029.4
VCX3B

variable charge, X-linked 3B

chr1_-_202896310 0.315 ENST00000367261.3
KLHL12
kelch-like family member 12
chr11_+_65479462 0.312 ENST00000377046.3
ENST00000352980.4
ENST00000341318.4
KAT5


K(lysine) acetyltransferase 5


chr9_-_131709858 0.312 ENST00000372586.3
DOLK
dolichol kinase
chr6_+_158589374 0.312 ENST00000607778.1
GTF2H5
general transcription factor IIH, polypeptide 5
chr22_+_19467261 0.312 ENST00000455750.1
ENST00000437685.2
ENST00000263201.1
ENST00000404724.3
CDC45



cell division cycle 45



chr9_-_123476612 0.309 ENST00000426959.1
MEGF9
multiple EGF-like-domains 9
chr16_+_85061367 0.308 ENST00000538274.1
ENST00000258180.3
KIAA0513

KIAA0513

chr4_-_103266626 0.307 ENST00000356736.4
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr5_-_150138551 0.301 ENST00000446090.2
ENST00000447998.2
DCTN4

dynactin 4 (p62)

chr1_-_155232047 0.300 ENST00000302631.3
SCAMP3
secretory carrier membrane protein 3
chr21_+_42792442 0.298 ENST00000398600.2
MX1
myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)
chr8_+_104033296 0.296 ENST00000521514.1
ENST00000518738.1
ATP6V1C1

ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1

chr10_+_26986582 0.295 ENST00000376215.5
ENST00000376203.5
PDSS1

prenyl (decaprenyl) diphosphate synthase, subunit 1

chr19_+_41305406 0.294 ENST00000406058.2
ENST00000593726.1
EGLN2

egl-9 family hypoxia-inducible factor 2

chr11_-_47664072 0.294 ENST00000542981.1
ENST00000530428.1
ENST00000302503.3
MTCH2


mitochondrial carrier 2


chr11_-_36310958 0.292 ENST00000532705.1
ENST00000263401.5
ENST00000452374.2
COMMD9


COMM domain containing 9


chr1_-_38019878 0.291 ENST00000296215.6
SNIP1
Smad nuclear interacting protein 1
chr21_-_38639601 0.291 ENST00000539844.1
ENST00000476950.1
ENST00000399001.1
DSCR3


Down syndrome critical region gene 3


chr12_-_56709786 0.290 ENST00000547423.1
ENST00000548360.1
ENST00000551475.1
RP11-977G19.10

CNPY2
Uncharacterized protein

canopy FGF signaling regulator 2
chr11_-_18343669 0.290 ENST00000396253.3
ENST00000349215.3
ENST00000438420.2
HPS5


Hermansky-Pudlak syndrome 5


chr11_-_64014379 0.290 ENST00000309318.3
PPP1R14B
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr21_-_38639813 0.289 ENST00000309117.6
ENST00000398998.1
DSCR3

Down syndrome critical region gene 3

chr17_+_40985407 0.287 ENST00000586114.1
ENST00000590720.1
ENST00000585805.1
ENST00000541124.1
ENST00000441946.2
ENST00000591152.1
ENST00000589469.1
ENST00000293362.3
ENST00000592169.1
PSME3








proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)








chr12_+_104359576 0.286 ENST00000392872.3
ENST00000436021.2
TDG

thymine-DNA glycosylase

chr7_+_100271446 0.285 ENST00000419828.1
ENST00000427895.1
GNB2

guanine nucleotide binding protein (G protein), beta polypeptide 2

chr1_+_26737253 0.284 ENST00000326279.6
LIN28A
lin-28 homolog A (C. elegans)
chr11_-_118972575 0.284 ENST00000432443.2
DPAGT1
dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
chr17_+_35306175 0.283 ENST00000225402.5
AATF
apoptosis antagonizing transcription factor
chr12_-_123849374 0.282 ENST00000602398.1
ENST00000602750.1
SBNO1

strawberry notch homolog 1 (Drosophila)

chr1_-_43638168 0.282 ENST00000431635.2
EBNA1BP2
EBNA1 binding protein 2
chr1_-_155232221 0.279 ENST00000355379.3
SCAMP3
secretory carrier membrane protein 3
chr9_-_123476719 0.279 ENST00000373930.3
MEGF9
multiple EGF-like-domains 9
chr1_-_53163992 0.274 ENST00000371538.3
SELRC1
cytochrome c oxidase assembly factor 7
chrX_+_118108571 0.271 ENST00000304778.7
LONRF3
LON peptidase N-terminal domain and ring finger 3
chr1_-_43637915 0.269 ENST00000236051.2
EBNA1BP2
EBNA1 binding protein 2
chr1_-_145610869 0.268 ENST00000334163.3
ENST00000369294.1
POLR3C

polymerase (RNA) III (DNA directed) polypeptide C (62kD)

chr10_+_22605374 0.267 ENST00000448361.1
COMMD3
COMM domain containing 3
chr4_-_76439596 0.267 ENST00000451788.1
ENST00000512706.1
RCHY1

ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase

chrX_+_48433326 0.264 ENST00000376755.1
RBM3
RNA binding motif (RNP1, RRM) protein 3
chr17_-_41116454 0.264 ENST00000427569.2
ENST00000430739.1
AARSD1

alanyl-tRNA synthetase domain containing 1

chr2_+_68384976 0.262 ENST00000263657.2
PNO1
partner of NOB1 homolog (S. cerevisiae)
chr12_+_28343353 0.259 ENST00000539107.1
CCDC91
coiled-coil domain containing 91
chr3_-_197024965 0.257 ENST00000392382.2
DLG1
discs, large homolog 1 (Drosophila)
chrX_+_48432892 0.254 ENST00000376759.3
ENST00000430348.2
RBM3

RNA binding motif (RNP1, RRM) protein 3

chr2_-_10588630 0.254 ENST00000234111.4
ODC1
ornithine decarboxylase 1
chr19_+_10812108 0.254 ENST00000250237.5
ENST00000592254.1
QTRT1

queuine tRNA-ribosyltransferase 1

chr10_+_99344104 0.254 ENST00000555577.1
ENST00000370649.3
PI4K2A
PI4K2A
phosphatidylinositol 4-kinase type 2 alpha
Phosphatidylinositol 4-kinase type 2-alpha; Uncharacterized protein
chr12_-_56709674 0.253 ENST00000549318.1
ENST00000551286.1
RP11-977G19.10
CNPY2
Uncharacterized protein
canopy FGF signaling regulator 2
chr10_-_43903217 0.252 ENST00000357065.4
HNRNPF
heterogeneous nuclear ribonucleoprotein F
chr18_+_9913977 0.252 ENST00000400000.2
ENST00000340541.4
VAPA

VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa

chr7_+_116593568 0.251 ENST00000446490.1
ST7
suppression of tumorigenicity 7
chr22_+_20105259 0.250 ENST00000416427.1
ENST00000421656.1
ENST00000423859.1
ENST00000418705.2
RANBP1



RAN binding protein 1



chr1_+_26798955 0.250 ENST00000361427.5
HMGN2
high mobility group nucleosomal binding domain 2
chr1_+_171750776 0.250 ENST00000458517.1
ENST00000362019.3
ENST00000367737.5
ENST00000361735.3
METTL13



methyltransferase like 13



chr6_-_39197226 0.249 ENST00000359534.3
KCNK5
potassium channel, subfamily K, member 5
chr10_-_120514720 0.249 ENST00000369151.3
ENST00000340214.4
CACUL1

CDK2-associated, cullin domain 1

chr10_-_14050522 0.249 ENST00000342409.2
FRMD4A
FERM domain containing 4A
chr21_+_45209394 0.248 ENST00000497547.1
RRP1
ribosomal RNA processing 1
chr12_+_104359641 0.246 ENST00000537100.1
TDG
thymine-DNA glycosylase
chr19_+_41305085 0.245 ENST00000303961.4
EGLN2
egl-9 family hypoxia-inducible factor 2
chrX_+_44732757 0.245 ENST00000377967.4
ENST00000536777.1
ENST00000382899.4
ENST00000543216.1
KDM6A



lysine (K)-specific demethylase 6A



chr19_+_30433110 0.244 ENST00000542441.2
ENST00000392271.1
URI1

URI1, prefoldin-like chaperone

chr1_-_111743285 0.243 ENST00000357640.4
DENND2D
DENN/MADD domain containing 2D
chrX_+_118108601 0.243 ENST00000371628.3
LONRF3
LON peptidase N-terminal domain and ring finger 3
chr2_-_148778258 0.242 ENST00000392857.5
ENST00000457954.1
ENST00000392858.1
ENST00000542387.1
ORC4



origin recognition complex, subunit 4



chr17_-_66951474 0.242 ENST00000269080.2
ABCA8
ATP-binding cassette, sub-family A (ABC1), member 8
chr7_+_100271355 0.238 ENST00000436220.1
ENST00000424361.1
GNB2

guanine nucleotide binding protein (G protein), beta polypeptide 2

chr12_+_51633061 0.237 ENST00000551313.1
DAZAP2
DAZ associated protein 2
chr2_-_40006357 0.237 ENST00000505747.1
THUMPD2
THUMP domain containing 2
chr14_-_65569186 0.236 ENST00000555932.1
ENST00000358664.4
ENST00000284165.6
ENST00000358402.4
ENST00000246163.2
ENST00000556979.1
ENST00000555667.1
ENST00000557746.1
ENST00000556443.1
MAX








MYC associated factor X








chrX_+_55744166 0.236 ENST00000374941.4
ENST00000414239.1
RRAGB

Ras-related GTP binding B

chr1_+_26737292 0.236 ENST00000254231.4
LIN28A
lin-28 homolog A (C. elegans)
chr16_-_30441293 0.235 ENST00000565758.1
ENST00000567983.1
ENST00000319285.4
DCTPP1


dCTP pyrophosphatase 1


chr21_-_40720974 0.235 ENST00000380748.1
HMGN1
high mobility group nucleosome binding domain 1

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.1 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.2 0.7 GO:0019858 cytosine metabolic process(GO:0019858)
0.2 3.0 GO:0048268 negative regulation of receptor-mediated endocytosis(GO:0048261) clathrin coat assembly(GO:0048268)
0.2 0.5 GO:0010586 miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.2 0.5 GO:0046449 allantoin metabolic process(GO:0000255) mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.2 0.5 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.2 0.8 GO:0032933 SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.1 1.0 GO:0045176 apical protein localization(GO:0045176)
0.1 2.6 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.1 0.4 GO:0021570 rhombomere 4 development(GO:0021570) facial nucleus development(GO:0021754)
0.1 1.0 GO:0071243 uroporphyrinogen III metabolic process(GO:0046502) response to fungicide(GO:0060992) cellular response to arsenic-containing substance(GO:0071243)
0.1 0.4 GO:0009202 purine deoxyribonucleotide biosynthetic process(GO:0009153) deoxyribonucleoside triphosphate biosynthetic process(GO:0009202)
0.1 0.4 GO:0046604 regulation of mitotic centrosome separation(GO:0046602) positive regulation of mitotic centrosome separation(GO:0046604)
0.1 0.5 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.1 0.5 GO:0010508 positive regulation of autophagy(GO:0010508)
0.1 1.2 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.1 0.3 GO:0032196 transposition, DNA-mediated(GO:0006313) transposition(GO:0032196)
0.1 0.4 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.1 0.4 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.1 0.3 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.1 0.4 GO:0009698 phenylpropanoid metabolic process(GO:0009698) coumarin metabolic process(GO:0009804)
0.1 0.8 GO:0045008 depyrimidination(GO:0045008)
0.1 0.1 GO:0021898 commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.1 3.8 GO:0015991 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.1 0.3 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.1 0.2 GO:0034625 fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.1 0.6 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 0.3 GO:0001575 globoside metabolic process(GO:0001575)
0.1 0.8 GO:0000076 DNA replication checkpoint(GO:0000076)
0.1 0.3 GO:0019348 polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.1 0.2 GO:0006041 glucosamine metabolic process(GO:0006041)
0.1 2.0 GO:0044349 nucleotide-excision repair, DNA damage removal(GO:0000718) DNA excision(GO:0044349)
0.1 0.2 GO:0015670 carbon dioxide transport(GO:0015670)
0.1 0.6 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.1 1.1 GO:0006596 polyamine biosynthetic process(GO:0006596)
0.1 0.9 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.1 0.5 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.1 0.4 GO:0007021 tubulin complex assembly(GO:0007021) acetylcholine transport(GO:0015870) acetate ester transport(GO:1901374)
0.1 0.2 GO:0043457 regulation of cellular respiration(GO:0043457)
0.1 0.1 GO:0045618 positive regulation of keratinocyte differentiation(GO:0045618)
0.1 2.6 GO:0048146 positive regulation of fibroblast proliferation(GO:0048146)
0.1 0.4 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.1 0.2 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.1 0.2 GO:0090467 arginine transport(GO:0015809) L-arginine import(GO:0043091) arginine import(GO:0090467) L-arginine transport(GO:1902023)
0.1 0.2 GO:0010520 regulation of reciprocal meiotic recombination(GO:0010520) positive regulation of meiotic nuclear division(GO:0045836) positive regulation of meiotic cell cycle(GO:0051446) regulation of meiosis I(GO:0060631)
0.0 0.4 GO:0006188 IMP biosynthetic process(GO:0006188) IMP metabolic process(GO:0046040)
0.0 0.5 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.3 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.3 GO:1901984 negative regulation of histone acetylation(GO:0035067) negative regulation of protein acetylation(GO:1901984) negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.0 0.2 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.2 GO:0060649 nipple development(GO:0060618) mammary gland bud elongation(GO:0060649) nipple morphogenesis(GO:0060658) nipple sheath formation(GO:0060659)
0.0 0.1 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.0 1.6 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.6 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.1 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0 0.1 GO:0045656 negative regulation of monocyte differentiation(GO:0045656)
0.0 0.6 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.7 GO:0048169 regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.0 0.5 GO:0055015 ventricular cardiac muscle cell development(GO:0055015)
0.0 0.2 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.3 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.3 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.6 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.5 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.0 1.0 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 0.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.8 GO:0035196 production of miRNAs involved in gene silencing by miRNA(GO:0035196)
0.0 0.4 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.7 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 0.2 GO:0060259 regulation of feeding behavior(GO:0060259)
0.0 0.1 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 1.2 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.1 GO:0060896 neural plate anterior/posterior regionalization(GO:0021999) neural plate pattern specification(GO:0060896) neural plate regionalization(GO:0060897)
0.0 0.2 GO:1903301 regulation of glucokinase activity(GO:0033131) positive regulation of glucokinase activity(GO:0033133) regulation of hexokinase activity(GO:1903299) positive regulation of hexokinase activity(GO:1903301)
0.0 0.2 GO:0009143 nucleoside triphosphate catabolic process(GO:0009143)
0.0 0.1 GO:0000491 small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0 0.1 GO:0070384 Harderian gland development(GO:0070384)
0.0 0.2 GO:0015904 tetracycline transport(GO:0015904)
0.0 0.4 GO:0046685 response to arsenic-containing substance(GO:0046685)
0.0 0.1 GO:0072387 flavin-containing compound biosynthetic process(GO:0042727) flavin adenine dinucleotide metabolic process(GO:0072387)
0.0 0.3 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.7 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.3 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.3 GO:0006378 mRNA polyadenylation(GO:0006378)
0.0 0.2 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.3 GO:0032647 interferon-alpha production(GO:0032607) regulation of interferon-alpha production(GO:0032647) positive regulation of interferon-alpha production(GO:0032727)
0.0 0.1 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.0 0.3 GO:0032481 positive regulation of type I interferon production(GO:0032481) positive regulation of interferon-beta production(GO:0032728)
0.0 0.2 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.0 0.3 GO:0098927 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0 0.1 GO:0033160 positive regulation of protein import into nucleus, translocation(GO:0033160)
0.0 0.1 GO:0035195 gene silencing by miRNA(GO:0035195)
0.0 0.2 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 0.2 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.1 GO:0034723 DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.1 GO:2000124 cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926) regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.2 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.6 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.1 GO:0046108 uridine metabolic process(GO:0046108)
0.0 0.4 GO:0035036 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036)
0.0 1.0 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 2.1 GO:0006364 rRNA processing(GO:0006364)
0.0 0.2 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.1 GO:1901798 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0 0.2 GO:0006069 ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.0 0.4 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.1 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.0 0.3 GO:0030500 regulation of bone mineralization(GO:0030500)
0.0 0.3 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.4 GO:0048704 embryonic skeletal system morphogenesis(GO:0048704)
0.0 0.0 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.2 GO:0002566 somatic diversification of immune receptors via somatic mutation(GO:0002566) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.5 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 0.1 GO:0006047 UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.0 1.3 GO:0006892 post-Golgi vesicle-mediated transport(GO:0006892)
0.0 0.2 GO:0035246 peptidyl-arginine N-methylation(GO:0035246)
0.0 1.6 GO:0048193 Golgi vesicle transport(GO:0048193)
0.0 0.2 GO:0006546 glycine catabolic process(GO:0006546)
0.0 0.1 GO:0019056 modulation by virus of host transcription(GO:0019056) regulation of sprouting of injured axon(GO:0048686) positive regulation of sprouting of injured axon(GO:0048687) regulation of axon extension involved in regeneration(GO:0048690) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.0 0.3 GO:0006400 tRNA modification(GO:0006400)
0.0 0.4 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.1 GO:0019985 translesion synthesis(GO:0019985)
0.0 0.1 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.0 0.1 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.1 GO:0043045 DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.0 0.5 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.1 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0 0.3 GO:0006490 dolichol-linked oligosaccharide biosynthetic process(GO:0006488) oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.0 0.2 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.6 GO:0042254 ribosome biogenesis(GO:0042254)
0.0 0.2 GO:0060351 cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.0 0.4 GO:0048255 RNA stabilization(GO:0043489) mRNA stabilization(GO:0048255)
0.0 0.1 GO:0015853 adenine transport(GO:0015853)
0.0 0.1 GO:0033572 ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.0 0.3 GO:0008333 endosome to lysosome transport(GO:0008333)
0.0 0.4 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.1 GO:1901343 negative regulation of angiogenesis(GO:0016525) negative regulation of vasculature development(GO:1901343) negative regulation of blood vessel morphogenesis(GO:2000181)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.3 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.1 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.2 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.1 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.2 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.1 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.1 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.1 GO:0051014 actin filament severing(GO:0051014)
0.0 0.2 GO:0006098 pentose-phosphate shunt(GO:0006098) glyceraldehyde-3-phosphate metabolic process(GO:0019682)
0.0 0.1 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.1 GO:0002724 T cell cytokine production(GO:0002369) regulation of T cell cytokine production(GO:0002724) positive regulation of T cell cytokine production(GO:0002726)
0.0 0.1 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.2 GO:0031397 negative regulation of protein ubiquitination(GO:0031397)
0.0 0.0 GO:0006382 adenosine to inosine editing(GO:0006382)
0.0 0.1 GO:0000731 DNA synthesis involved in DNA repair(GO:0000731)
0.0 0.0 GO:0021615 glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.2 GO:0046902 regulation of mitochondrial membrane permeability(GO:0046902) regulation of membrane permeability(GO:0090559)
0.0 0.0 GO:0002467 germinal center formation(GO:0002467)
0.0 0.4 GO:0006612 protein targeting to membrane(GO:0006612)
0.0 0.1 GO:0034643 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.0 0.0 GO:0009174 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0 0.0 GO:0010273 regulation of oxidative phosphorylation(GO:0002082) detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.0 0.7 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.1 GO:0042977 activation of JAK2 kinase activity(GO:0042977)
0.0 0.1 GO:0048070 regulation of developmental pigmentation(GO:0048070)
0.0 0.1 GO:0006903 vesicle targeting(GO:0006903)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.4 1.3 GO:0030904 retromer complex(GO:0030904)
0.3 1.0 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.2 3.0 GO:0030122 AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.2 0.6 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.2 0.7 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.2 1.3 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1 1.5 GO:0032040 small-subunit processome(GO:0032040)
0.1 1.9 GO:0005675 holo TFIIH complex(GO:0005675)
0.1 0.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 0.4 GO:0031083 BLOC complex(GO:0031082) BLOC-1 complex(GO:0031083)
0.1 0.8 GO:0042382 paraspeckles(GO:0042382)
0.1 0.4 GO:0070695 FHF complex(GO:0070695)
0.1 2.9 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 0.3 GO:0000145 exocyst(GO:0000145)
0.1 1.2 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.1 0.4 GO:0001740 Barr body(GO:0001740)
0.1 0.6 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 0.2 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.1 2.1 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 0.2 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 0.8 GO:0042589 zymogen granule membrane(GO:0042589)
0.1 0.7 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 1.3 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.1 1.0 GO:0061200 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.1 0.2 GO:0071001 U4/U6 snRNP(GO:0071001)
0.1 0.5 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 0.7 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 0.2 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.1 0.7 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 0.2 GO:0009279 cell outer membrane(GO:0009279)
0.0 0.3 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.2 GO:0000125 PCAF complex(GO:0000125)
0.0 0.3 GO:0030897 HOPS complex(GO:0030897)
0.0 0.2 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.4 GO:0042555 MCM complex(GO:0042555)
0.0 0.5 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.0 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.6 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.0 0.6 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.4 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.2 GO:0005642 annulate lamellae(GO:0005642)
0.0 1.0 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.2 GO:0001741 XY body(GO:0001741)
0.0 0.3 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 0.9 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.1 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.1 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.5 GO:0005771 multivesicular body(GO:0005771)
0.0 0.2 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.2 GO:0030914 STAGA complex(GO:0030914)
0.0 0.6 GO:0001772 immunological synapse(GO:0001772)
0.0 0.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.2 GO:0002102 podosome(GO:0002102)
0.0 0.1 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.3 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.1 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.7 GO:0030530 obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0 0.1 GO:0030681 nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0 1.7 GO:0005770 late endosome(GO:0005770)
0.0 0.1 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.2 GO:0031941 filamentous actin(GO:0031941)
0.0 0.4 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.2 GO:0046930 pore complex(GO:0046930)
0.0 0.2 GO:0044452 nucleolar part(GO:0044452)
0.0 0.1 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.1 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471) proton-transporting V-type ATPase complex(GO:0033176)
0.0 0.1 GO:0071778 obsolete WINAC complex(GO:0071778)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.0 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.4 2.5 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.3 1.0 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
0.3 0.8 GO:0008263 pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
0.2 2.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.2 0.5 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.2 0.8 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.1 0.4 GO:0004730 pseudouridylate synthase activity(GO:0004730)
0.1 2.9 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 0.3 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.1 0.5 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 0.2 GO:0008493 tetracycline transporter activity(GO:0008493)
0.1 0.4 GO:0015925 galactosidase activity(GO:0015925)
0.1 0.3 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.1 0.8 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 0.3 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.1 0.2 GO:0032552 deoxyribonucleotide binding(GO:0032552)
0.1 0.5 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.1 0.3 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 2.0 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 0.4 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.1 0.3 GO:0004803 transposase activity(GO:0004803)
0.1 0.9 GO:0000339 RNA cap binding(GO:0000339)
0.1 0.5 GO:0019826 oxygen sensor activity(GO:0019826)
0.1 1.6 GO:0019003 GDP binding(GO:0019003)
0.1 1.8 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.1 0.2 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.1 0.2 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.0 0.5 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.5 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.2 GO:0009922 fatty acid elongase activity(GO:0009922)
0.0 0.2 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0 0.2 GO:0034701 tripeptidase activity(GO:0034701)
0.0 0.3 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.3 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.4 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.2 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 0.3 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.3 GO:0008159 obsolete positive transcription elongation factor activity(GO:0008159)
0.0 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.2 GO:0000827 inositol-1,3,4,5,6-pentakisphosphate kinase activity(GO:0000827) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.2 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 1.0 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769)
0.0 0.1 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.0 0.4 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.5 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.1 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.0 0.2 GO:0004766 spermidine synthase activity(GO:0004766)
0.0 2.9 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 0.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 2.6 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.0 1.0 GO:0030552 cAMP binding(GO:0030552)
0.0 0.1 GO:0004348 glucosylceramidase activity(GO:0004348)
0.0 0.2 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.2 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.7 GO:0043022 ribosome binding(GO:0043022)
0.0 0.2 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.0 0.2 GO:0048256 flap endonuclease activity(GO:0048256)
0.0 1.0 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.5 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.5 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.1 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.4 GO:0019206 nucleoside kinase activity(GO:0019206)
0.0 0.3 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0 0.1 GO:0000247 C-8 sterol isomerase activity(GO:0000247)
0.0 0.1 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.1 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.0 0.1 GO:0005345 purine nucleobase transmembrane transporter activity(GO:0005345)
0.0 0.6 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.7 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.2 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.0 1.0 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.1 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.4 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.2 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.4 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.0 0.1 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.3 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.2 GO:0061659 ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0 0.2 GO:0015288 porin activity(GO:0015288)
0.0 0.4 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.5 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.8 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.1 GO:0032138 single base insertion or deletion binding(GO:0032138)
0.0 0.3 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.5 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.2 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.0 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.1 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.3 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.4 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.1 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.2 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.0 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.6 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
0.0 0.2 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.1 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.2 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.4 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.5 GO:0002039 p53 binding(GO:0002039)
0.0 0.4 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.0 0.0 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.0 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.3 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.0 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.2 GO:0005372 water transmembrane transporter activity(GO:0005372) water channel activity(GO:0015250)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.0 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.0 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0017069 snRNA binding(GO:0017069)
0.0 0.1 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.0 GO:0000403 four-way junction DNA binding(GO:0000400) Y-form DNA binding(GO:0000403)
0.0 0.3 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.1 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.0 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 2.6 GO:0003924 GTPase activity(GO:0003924)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.7 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 0.9 ST_P38_MAPK_PATHWAY p38 MAPK Pathway