Motif ID: MBD2
Z-value: 2.100
Transcription factors associated with MBD2:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| MBD2 | ENSG00000134046.7 | MBD2 |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 2.2 | GO:0033197 | response to vitamin E(GO:0033197) |
| 0.5 | 5.4 | GO:0031017 | exocrine pancreas development(GO:0031017) |
| 0.5 | 1.6 | GO:0071679 | commissural neuron axon guidance(GO:0071679) |
| 0.5 | 1.4 | GO:0060596 | mammary placode formation(GO:0060596) |
| 0.5 | 1.4 | GO:0001300 | chronological cell aging(GO:0001300) detection of hypoxia(GO:0070483) |
| 0.4 | 1.3 | GO:2000096 | positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096) |
| 0.3 | 0.3 | GO:0072048 | pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048) |
| 0.3 | 1.9 | GO:0051387 | negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387) |
| 0.3 | 2.2 | GO:0007185 | transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185) |
| 0.3 | 1.2 | GO:0031643 | positive regulation of myelination(GO:0031643) |
| 0.3 | 4.3 | GO:0060391 | positive regulation of SMAD protein import into nucleus(GO:0060391) |
| 0.3 | 1.1 | GO:0008298 | intracellular mRNA localization(GO:0008298) |
| 0.3 | 1.0 | GO:0042271 | susceptibility to natural killer cell mediated cytotoxicity(GO:0042271) |
| 0.2 | 0.5 | GO:0014029 | neural crest formation(GO:0014029) neural crest cell fate commitment(GO:0014034) |
| 0.2 | 1.2 | GO:0048669 | collateral sprouting in absence of injury(GO:0048669) |
| 0.2 | 6.7 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.2 | 1.0 | GO:0046607 | positive regulation of centrosome cycle(GO:0046607) |
| 0.2 | 1.4 | GO:0030579 | ubiquitin-dependent SMAD protein catabolic process(GO:0030579) |
| 0.2 | 1.3 | GO:0060346 | bone trabecula formation(GO:0060346) bone trabecula morphogenesis(GO:0061430) |
| 0.2 | 0.2 | GO:0060677 | ureteric bud elongation(GO:0060677) |
| 0.2 | 0.7 | GO:0060272 | embryonic skeletal joint morphogenesis(GO:0060272) embryonic skeletal joint development(GO:0072498) |
| 0.2 | 0.7 | GO:0021506 | anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995) |
| 0.2 | 0.7 | GO:0071071 | regulation of phosphatidylinositol biosynthetic process(GO:0010511) regulation of phospholipid biosynthetic process(GO:0071071) |
| 0.2 | 1.7 | GO:0060762 | regulation of branching involved in mammary gland duct morphogenesis(GO:0060762) |
| 0.2 | 3.3 | GO:0043114 | regulation of vascular permeability(GO:0043114) |
| 0.2 | 0.6 | GO:0048170 | positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743) positive regulation of long-term neuronal synaptic plasticity(GO:0048170) long-term synaptic potentiation(GO:0060291) |
| 0.1 | 0.4 | GO:0070634 | transepithelial ammonium transport(GO:0070634) |
| 0.1 | 0.6 | GO:0031999 | negative regulation of fatty acid beta-oxidation(GO:0031999) |
| 0.1 | 1.4 | GO:0007216 | G-protein coupled glutamate receptor signaling pathway(GO:0007216) |
| 0.1 | 0.9 | GO:0002726 | positive regulation of T cell cytokine production(GO:0002726) |
| 0.1 | 0.4 | GO:0070544 | histone H3-K36 demethylation(GO:0070544) |
| 0.1 | 0.4 | GO:0033025 | mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) PMA-inducible membrane protein ectodomain proteolysis(GO:0051088) |
| 0.1 | 1.9 | GO:0006071 | glycerol metabolic process(GO:0006071) |
| 0.1 | 1.2 | GO:0032922 | circadian regulation of gene expression(GO:0032922) |
| 0.1 | 3.2 | GO:0042554 | superoxide anion generation(GO:0042554) |
| 0.1 | 0.3 | GO:0032119 | sequestering of zinc ion(GO:0032119) antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) regulation of sequestering of zinc ion(GO:0061088) |
| 0.1 | 7.0 | GO:0017148 | negative regulation of translation(GO:0017148) |
| 0.1 | 2.4 | GO:0034199 | activation of protein kinase A activity(GO:0034199) |
| 0.1 | 0.8 | GO:0015014 | heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014) |
| 0.1 | 10.4 | GO:0008154 | actin polymerization or depolymerization(GO:0008154) |
| 0.1 | 0.5 | GO:0046541 | saliva secretion(GO:0046541) |
| 0.1 | 0.5 | GO:0030263 | apoptotic chromosome condensation(GO:0030263) |
| 0.1 | 0.2 | GO:0044314 | protein K27-linked ubiquitination(GO:0044314) |
| 0.1 | 7.9 | GO:0035023 | regulation of Rho protein signal transduction(GO:0035023) |
| 0.1 | 0.8 | GO:0051319 | mitotic G2 phase(GO:0000085) G2 phase(GO:0051319) |
| 0.1 | 0.3 | GO:0060363 | cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094) |
| 0.1 | 0.1 | GO:0061188 | regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188) |
| 0.1 | 0.2 | GO:0001973 | adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588) |
| 0.1 | 0.6 | GO:0006743 | ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) |
| 0.1 | 0.5 | GO:0006600 | creatine metabolic process(GO:0006600) |
| 0.1 | 0.3 | GO:0051045 | negative regulation of membrane protein ectodomain proteolysis(GO:0051045) |
| 0.0 | 2.9 | GO:0051084 | 'de novo' posttranslational protein folding(GO:0051084) |
| 0.0 | 0.2 | GO:0090343 | positive regulation of cell aging(GO:0090343) |
| 0.0 | 1.9 | GO:0050772 | positive regulation of axonogenesis(GO:0050772) |
| 0.0 | 1.5 | GO:0006783 | heme biosynthetic process(GO:0006783) |
| 0.0 | 0.1 | GO:0035330 | regulation of hippo signaling(GO:0035330) |
| 0.0 | 1.4 | GO:0031532 | actin cytoskeleton reorganization(GO:0031532) |
| 0.0 | 0.1 | GO:0043371 | negative regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043371) negative regulation of T-helper cell differentiation(GO:0045623) negative regulation of CD4-positive, alpha-beta T cell activation(GO:2000515) |
| 0.0 | 1.0 | GO:0050773 | regulation of dendrite development(GO:0050773) |
| 0.0 | 1.0 | GO:0006911 | phagocytosis, engulfment(GO:0006911) membrane invagination(GO:0010324) |
| 0.0 | 0.1 | GO:0032223 | negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212) |
| 0.0 | 0.5 | GO:0014003 | oligodendrocyte development(GO:0014003) |
| 0.0 | 0.1 | GO:0032927 | positive regulation of activin receptor signaling pathway(GO:0032927) |
| 0.0 | 0.2 | GO:0051092 | positive regulation of NF-kappaB transcription factor activity(GO:0051092) |
| 0.0 | 0.1 | GO:0043418 | cysteine biosynthetic process from serine(GO:0006535) homoserine metabolic process(GO:0009092) cysteine biosynthetic process via cystathionine(GO:0019343) transsulfuration(GO:0019346) homocysteine catabolic process(GO:0043418) |
| 0.0 | 5.0 | GO:0006633 | fatty acid biosynthetic process(GO:0006633) |
| 0.0 | 4.9 | GO:0043087 | regulation of GTPase activity(GO:0043087) |
| 0.0 | 0.1 | GO:1903960 | negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192) |
| 0.0 | 0.6 | GO:0006378 | mRNA polyadenylation(GO:0006378) |
| 0.0 | 1.2 | GO:0030512 | negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845) |
| 0.0 | 0.1 | GO:0007181 | transforming growth factor beta receptor complex assembly(GO:0007181) |
| 0.0 | 1.5 | GO:0007422 | peripheral nervous system development(GO:0007422) |
| 0.0 | 0.2 | GO:0070189 | kynurenine metabolic process(GO:0070189) |
| 0.0 | 1.5 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
| 0.0 | 1.0 | GO:0007613 | memory(GO:0007613) |
| 0.0 | 0.1 | GO:0018027 | peptidyl-lysine dimethylation(GO:0018027) |
| 0.0 | 0.5 | GO:0030968 | endoplasmic reticulum unfolded protein response(GO:0030968) cellular response to unfolded protein(GO:0034620) |
| 0.0 | 0.1 | GO:0046952 | cellular ketone body metabolic process(GO:0046950) ketone body catabolic process(GO:0046952) |
| 0.0 | 2.0 | GO:0007218 | neuropeptide signaling pathway(GO:0007218) |
| 0.0 | 0.3 | GO:0007128 | meiotic prophase I(GO:0007128) |
| 0.0 | 0.1 | GO:0021955 | central nervous system projection neuron axonogenesis(GO:0021952) central nervous system neuron axonogenesis(GO:0021955) |
| 0.0 | 0.1 | GO:0042753 | positive regulation of circadian rhythm(GO:0042753) |
| 0.0 | 0.5 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
| 0.0 | 0.6 | GO:0006333 | chromatin assembly or disassembly(GO:0006333) |
| 0.0 | 1.1 | GO:0030521 | androgen receptor signaling pathway(GO:0030521) |
| 0.0 | 0.1 | GO:0045075 | interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075) |
| 0.0 | 0.3 | GO:0008088 | axo-dendritic transport(GO:0008088) |
| 0.0 | 0.3 | GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I(GO:0002474) |
| 0.0 | 0.2 | GO:0006198 | cAMP catabolic process(GO:0006198) |
| 0.0 | 0.5 | GO:0048010 | vascular endothelial growth factor receptor signaling pathway(GO:0048010) |
| 0.0 | 0.3 | GO:0031175 | neuron projection development(GO:0031175) |
| 0.0 | 0.1 | GO:0007199 | G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199) |
| 0.0 | 0.3 | GO:0046626 | regulation of insulin receptor signaling pathway(GO:0046626) regulation of cellular response to insulin stimulus(GO:1900076) |
| 0.0 | 0.5 | GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184) |
| 0.0 | 0.1 | GO:0032000 | positive regulation of fatty acid beta-oxidation(GO:0032000) |
| 0.0 | 0.0 | GO:0019046 | release from viral latency(GO:0019046) |
| 0.0 | 0.6 | GO:0042472 | inner ear morphogenesis(GO:0042472) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 2.9 | GO:0016012 | sarcoglycan complex(GO:0016012) |
| 0.2 | 1.4 | GO:0070022 | transforming growth factor beta receptor homodimeric complex(GO:0070022) |
| 0.2 | 1.2 | GO:0051233 | spindle midzone(GO:0051233) |
| 0.2 | 7.6 | GO:0098636 | integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636) |
| 0.1 | 1.0 | GO:0031616 | spindle pole centrosome(GO:0031616) |
| 0.1 | 0.9 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
| 0.1 | 1.3 | GO:0001527 | microfibril(GO:0001527) |
| 0.1 | 0.4 | GO:0045298 | tubulin complex(GO:0045298) |
| 0.1 | 0.7 | GO:0098643 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
| 0.1 | 4.4 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
| 0.0 | 0.7 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.0 | 0.4 | GO:0014731 | spectrin-associated cytoskeleton(GO:0014731) |
| 0.0 | 1.4 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 0.0 | 2.7 | GO:0032587 | ruffle membrane(GO:0032587) |
| 0.0 | 0.9 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.0 | 1.0 | GO:0008021 | synaptic vesicle(GO:0008021) exocytic vesicle(GO:0070382) |
| 0.0 | 2.1 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
| 0.0 | 0.8 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 0.0 | 0.2 | GO:0005638 | lamin filament(GO:0005638) |
| 0.0 | 0.3 | GO:0035253 | ciliary rootlet(GO:0035253) |
| 0.0 | 0.1 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
| 0.0 | 1.0 | GO:0042641 | actomyosin(GO:0042641) |
| 0.0 | 0.3 | GO:0019867 | mitochondrial outer membrane(GO:0005741) outer membrane(GO:0019867) organelle outer membrane(GO:0031968) |
| 0.0 | 3.7 | GO:0019898 | extrinsic component of membrane(GO:0019898) |
| 0.0 | 0.1 | GO:0070552 | BRISC complex(GO:0070552) |
| 0.0 | 0.5 | GO:0043034 | costamere(GO:0043034) |
| 0.0 | 0.1 | GO:0033269 | internode region of axon(GO:0033269) |
| 0.0 | 6.8 | GO:0030659 | cytoplasmic vesicle membrane(GO:0030659) |
| 0.0 | 3.2 | GO:0005925 | focal adhesion(GO:0005925) |
| 0.0 | 0.2 | GO:0031528 | microvillus membrane(GO:0031528) |
| 0.0 | 1.3 | GO:0014069 | postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572) |
| 0.0 | 1.2 | GO:0030426 | growth cone(GO:0030426) |
| 0.0 | 1.2 | GO:0005746 | mitochondrial respiratory chain(GO:0005746) |
| 0.0 | 0.3 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 0.0 | 0.2 | GO:0033116 | endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116) |
| 0.0 | 0.3 | GO:0030117 | membrane coat(GO:0030117) coated membrane(GO:0048475) |
| 0.0 | 0.3 | GO:0042612 | MHC class I protein complex(GO:0042612) |
| 0.0 | 21.2 | GO:0005856 | cytoskeleton(GO:0005856) |
| 0.0 | 4.3 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.0 | 0.1 | GO:0032420 | stereocilium(GO:0032420) |
| 0.0 | 0.9 | GO:0044433 | cytoplasmic vesicle part(GO:0044433) |
| 0.0 | 0.3 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.0 | 0.6 | GO:0042734 | presynaptic membrane(GO:0042734) |
| 0.0 | 0.3 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.0 | 7.3 | GO:0048027 | mRNA 5'-UTR binding(GO:0048027) |
| 0.5 | 1.4 | GO:0016524 | latrotoxin receptor activity(GO:0016524) |
| 0.4 | 1.3 | GO:0019797 | procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544) |
| 0.4 | 3.2 | GO:0019826 | oxygen sensor activity(GO:0019826) |
| 0.3 | 1.9 | GO:0008889 | glycerophosphodiester phosphodiesterase activity(GO:0008889) |
| 0.3 | 1.4 | GO:0005534 | galactose binding(GO:0005534) |
| 0.3 | 1.9 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
| 0.2 | 4.9 | GO:0008143 | poly(A) binding(GO:0008143) |
| 0.2 | 0.8 | GO:0042328 | heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328) N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509) |
| 0.2 | 0.9 | GO:0008327 | methyl-CpG binding(GO:0008327) |
| 0.2 | 5.4 | GO:0005159 | insulin-like growth factor receptor binding(GO:0005159) |
| 0.2 | 1.1 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 0.2 | 4.1 | GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding(GO:0005546) |
| 0.1 | 0.4 | GO:0050510 | N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510) |
| 0.1 | 1.2 | GO:0051425 | acetylcholine receptor binding(GO:0033130) PTB domain binding(GO:0051425) |
| 0.1 | 0.5 | GO:0005105 | type 1 fibroblast growth factor receptor binding(GO:0005105) |
| 0.1 | 1.4 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
| 0.1 | 0.5 | GO:0008420 | CTD phosphatase activity(GO:0008420) |
| 0.1 | 1.6 | GO:0004029 | aldehyde dehydrogenase (NAD) activity(GO:0004029) |
| 0.1 | 0.6 | GO:0003998 | acylphosphatase activity(GO:0003998) |
| 0.1 | 2.5 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
| 0.1 | 8.2 | GO:0035091 | phosphatidylinositol binding(GO:0035091) |
| 0.1 | 8.8 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.1 | 1.4 | GO:0016565 | obsolete general transcriptional repressor activity(GO:0016565) |
| 0.1 | 2.2 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
| 0.1 | 1.6 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.1 | 0.3 | GO:0008467 | [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467) |
| 0.1 | 0.4 | GO:0004169 | dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169) |
| 0.1 | 0.4 | GO:0051864 | histone demethylase activity (H3-K36 specific)(GO:0051864) |
| 0.1 | 0.5 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
| 0.1 | 1.6 | GO:0004016 | adenylate cyclase activity(GO:0004016) |
| 0.1 | 1.0 | GO:0043395 | heparan sulfate proteoglycan binding(GO:0043395) |
| 0.1 | 0.4 | GO:0034187 | obsolete apolipoprotein E binding(GO:0034187) |
| 0.1 | 0.4 | GO:0030506 | ankyrin binding(GO:0030506) |
| 0.1 | 0.2 | GO:0070548 | 1-aminocyclopropane-1-carboxylate synthase activity(GO:0016847) L-glutamine aminotransferase activity(GO:0070548) |
| 0.1 | 1.4 | GO:0030159 | receptor signaling complex scaffold activity(GO:0030159) |
| 0.1 | 0.6 | GO:0005021 | vascular endothelial growth factor-activated receptor activity(GO:0005021) |
| 0.0 | 1.3 | GO:0005001 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
| 0.0 | 3.3 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
| 0.0 | 1.1 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.0 | 0.6 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.0 | 0.4 | GO:0005138 | interleukin-6 receptor binding(GO:0005138) |
| 0.0 | 1.2 | GO:0004129 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 0.0 | 4.8 | GO:0004725 | protein tyrosine phosphatase activity(GO:0004725) |
| 0.0 | 0.7 | GO:1905030 | voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030) |
| 0.0 | 0.2 | GO:0004652 | polynucleotide adenylyltransferase activity(GO:0004652) |
| 0.0 | 0.1 | GO:0016362 | activin receptor activity, type II(GO:0016362) |
| 0.0 | 0.2 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
| 0.0 | 0.1 | GO:0004122 | cystathionine beta-synthase activity(GO:0004122) |
| 0.0 | 0.3 | GO:0090599 | alpha-glucosidase activity(GO:0090599) |
| 0.0 | 0.5 | GO:0072349 | modified amino acid transmembrane transporter activity(GO:0072349) |
| 0.0 | 0.1 | GO:0046975 | histone methyltransferase activity (H3-K36 specific)(GO:0046975) |
| 0.0 | 0.1 | GO:0003990 | acetylcholinesterase activity(GO:0003990) |
| 0.0 | 1.5 | GO:0008301 | DNA binding, bending(GO:0008301) |
| 0.0 | 0.7 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.0 | 0.3 | GO:0000339 | RNA cap binding(GO:0000339) |
| 0.0 | 0.4 | GO:0042809 | vitamin D receptor binding(GO:0042809) |
| 0.0 | 0.3 | GO:0032393 | MHC class I receptor activity(GO:0032393) |
| 0.0 | 0.5 | GO:0030553 | cGMP binding(GO:0030553) |
| 0.0 | 0.1 | GO:0051019 | mitogen-activated protein kinase binding(GO:0051019) |
| 0.0 | 1.0 | GO:0030165 | PDZ domain binding(GO:0030165) |
| 0.0 | 0.5 | GO:0005242 | inward rectifier potassium channel activity(GO:0005242) |
| 0.0 | 5.9 | GO:0005096 | GTPase activator activity(GO:0005096) |
| 0.0 | 0.4 | GO:0004407 | histone deacetylase activity(GO:0004407) |
| 0.0 | 0.1 | GO:0016802 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
| 0.0 | 1.6 | GO:0051020 | GTPase binding(GO:0051020) |
| 0.0 | 0.2 | GO:0003706 | obsolete ligand-regulated transcription factor activity(GO:0003706) |
| 0.0 | 0.6 | GO:0016709 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709) |
| 0.0 | 0.1 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
| 0.0 | 0.1 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) bicarbonate transmembrane transporter activity(GO:0015106) |
| 0.0 | 0.1 | GO:0008046 | axon guidance receptor activity(GO:0008046) |
| 0.0 | 0.1 | GO:0004095 | carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416) |
| 0.0 | 0.8 | GO:0030695 | GTPase regulator activity(GO:0030695) |
| 0.0 | 0.3 | GO:0051721 | protein phosphatase 2A binding(GO:0051721) |
| 0.0 | 5.8 | GO:0003779 | actin binding(GO:0003779) |
| 0.0 | 0.2 | GO:0051059 | NF-kappaB binding(GO:0051059) |
| 0.0 | 0.0 | GO:0048020 | CCR chemokine receptor binding(GO:0048020) |
| 0.0 | 0.1 | GO:0008967 | phosphoglycolate phosphatase activity(GO:0008967) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 7.6 | SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.1 | 2.5 | SA_REG_CASCADE_OF_CYCLIN_EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.1 | 8.6 | ST_INTEGRIN_SIGNALING_PATHWAY | Integrin Signaling Pathway |
