Motif ID: MEIS1

Z-value: 1.070


Transcription factors associated with MEIS1:

Gene SymbolEntrez IDGene Name
MEIS1 ENSG00000143995.15 MEIS1



Activity profile for motif MEIS1.

activity profile for motif MEIS1


Sorted Z-values histogram for motif MEIS1

Sorted Z-values for motif MEIS1



Network of associatons between targets according to the STRING database.



First level regulatory network of MEIS1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_-_16727978 2.287 ENST00000418777.1
ENST00000468187.2
BNC2

basonuclin 2

chr12_-_91505608 1.653 ENST00000266718.4
LUM
lumican
chr2_-_211179883 1.649 ENST00000352451.3
MYL1
myosin, light chain 1, alkali; skeletal, fast
chr15_+_33010175 1.452 ENST00000300177.4
ENST00000560677.1
ENST00000560830.1
GREM1


gremlin 1, DAN family BMP antagonist


chr9_-_79307096 1.431 ENST00000376717.2
ENST00000223609.6
ENST00000443509.2
PRUNE2


prune homolog 2 (Drosophila)


chr18_-_52969844 1.386 ENST00000561831.3
TCF4
transcription factor 4
chr11_+_35198243 1.336 ENST00000528455.1
CD44
CD44 molecule (Indian blood group)
chr1_+_114522049 1.256 ENST00000369551.1
ENST00000320334.4
OLFML3

olfactomedin-like 3

chr10_+_54074033 1.201 ENST00000373970.3
DKK1
dickkopf WNT signaling pathway inhibitor 1
chr2_-_56150910 1.175 ENST00000424836.2
ENST00000438672.1
ENST00000440439.1
ENST00000429909.1
ENST00000424207.1
ENST00000452337.1
ENST00000355426.3
ENST00000439193.1
ENST00000421664.1
EFEMP1








EGF containing fibulin-like extracellular matrix protein 1








chr7_-_137028534 1.163 ENST00000348225.2
PTN
pleiotrophin
chr2_-_175870085 1.153 ENST00000409156.3
CHN1
chimerin 1
chr13_+_102104980 1.097 ENST00000545560.2
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr13_+_102104952 1.093 ENST00000376180.3
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr18_-_21891460 1.079 ENST00000357041.4
OSBPL1A
oxysterol binding protein-like 1A
chr3_-_120170052 1.067 ENST00000295633.3
FSTL1
follistatin-like 1
chr8_-_120651020 1.000 ENST00000522826.1
ENST00000520066.1
ENST00000259486.6
ENST00000075322.6
ENPP2



ectonucleotide pyrophosphatase/phosphodiesterase 2



chr12_+_26348246 0.999 ENST00000422622.2
SSPN
sarcospan
chr1_-_155211017 0.991 ENST00000536770.1
ENST00000368373.3
GBA

glucosidase, beta, acid

chr1_+_26605618 0.987 ENST00000270792.5
SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3
chr6_-_169654139 0.974 ENST00000366787.3
THBS2
thrombospondin 2
chr5_+_125758865 0.965 ENST00000542322.1
ENST00000544396.1
GRAMD3

GRAM domain containing 3

chr16_+_31044812 0.953 ENST00000313843.3
STX4
syntaxin 4
chr5_+_82767284 0.946 ENST00000265077.3
VCAN
versican
chr5_+_125758813 0.938 ENST00000285689.3
ENST00000515200.1
GRAMD3

GRAM domain containing 3

chr5_+_82767487 0.931 ENST00000343200.5
ENST00000342785.4
VCAN

versican

chr11_-_111794446 0.917 ENST00000527950.1
CRYAB
crystallin, alpha B
chr6_-_46293378 0.912 ENST00000330430.6
RCAN2
regulator of calcineurin 2
chr11_-_111781610 0.906 ENST00000525823.1
CRYAB
crystallin, alpha B
chr9_-_113341985 0.901 ENST00000374469.1
SVEP1
sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
chr8_-_108510224 0.896 ENST00000517746.1
ENST00000297450.3
ANGPT1

angiopoietin 1

chrX_+_135251783 0.894 ENST00000394153.2
FHL1
four and a half LIM domains 1
chr11_-_111781454 0.890 ENST00000533280.1
CRYAB
crystallin, alpha B
chr4_+_77870960 0.877 ENST00000505788.1
ENST00000510515.1
ENST00000504637.1
SEPT11


septin 11


chr7_-_137028498 0.869 ENST00000393083.2
PTN
pleiotrophin
chr9_+_34652164 0.865 ENST00000441545.2
ENST00000553620.1
IL11RA

interleukin 11 receptor, alpha

chr3_-_127541194 0.864 ENST00000453507.2
MGLL
monoglyceride lipase
chr17_-_76899275 0.855 ENST00000322630.2
ENST00000586713.1
DDC8

Protein DDC8 homolog

chr21_+_30502806 0.852 ENST00000399928.1
ENST00000399926.1
MAP3K7CL

MAP3K7 C-terminal like

chr3_-_127541679 0.841 ENST00000265052.5
MGLL
monoglyceride lipase
chr6_+_39760783 0.836 ENST00000398904.2
ENST00000538976.1
DAAM2

dishevelled associated activator of morphogenesis 2

chr5_+_49962495 0.805 ENST00000515175.1
PARP8
poly (ADP-ribose) polymerase family, member 8
chr8_-_18744528 0.798 ENST00000523619.1
PSD3
pleckstrin and Sec7 domain containing 3
chr2_+_5832799 0.797 ENST00000322002.3
SOX11
SRY (sex determining region Y)-box 11
chr13_-_67802549 0.786 ENST00000328454.5
ENST00000377865.2
PCDH9

protocadherin 9

chr2_-_179672142 0.784 ENST00000342992.6
ENST00000360870.5
ENST00000460472.2
ENST00000589042.1
ENST00000591111.1
ENST00000342175.6
ENST00000359218.5
TTN






titin






chr10_-_33623564 0.780 ENST00000374875.1
ENST00000374822.4
NRP1

neuropilin 1

chr8_-_49834299 0.779 ENST00000396822.1
SNAI2
snail family zinc finger 2
chr2_-_56150184 0.778 ENST00000394554.1
EFEMP1
EGF containing fibulin-like extracellular matrix protein 1
chr9_-_113342160 0.774 ENST00000401783.2
ENST00000374461.1
SVEP1

sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1

chr9_-_117880477 0.771 ENST00000534839.1
ENST00000340094.3
ENST00000535648.1
ENST00000346706.3
ENST00000345230.3
ENST00000350763.4
TNC





tenascin C





chr8_-_42065187 0.770 ENST00000270189.6
ENST00000352041.3
ENST00000220809.4
PLAT


plasminogen activator, tissue


chr11_+_35211511 0.768 ENST00000524922.1
CD44
CD44 molecule (Indian blood group)
chr14_-_92413353 0.764 ENST00000556154.1
FBLN5
fibulin 5
chr2_-_145275228 0.764 ENST00000427902.1
ENST00000409487.3
ENST00000470879.1
ENST00000435831.1
ZEB2



zinc finger E-box binding homeobox 2



chr11_-_111781554 0.747 ENST00000526167.1
ENST00000528961.1
CRYAB

crystallin, alpha B

chr17_-_46623441 0.739 ENST00000330070.4
HOXB2
homeobox B2
chr8_-_42065075 0.733 ENST00000429089.2
ENST00000519510.1
ENST00000429710.2
ENST00000524009.1
PLAT



plasminogen activator, tissue



chr2_+_33359687 0.729 ENST00000402934.1
ENST00000404525.1
ENST00000407925.1
LTBP1


latent transforming growth factor beta binding protein 1


chr2_+_33359646 0.729 ENST00000390003.4
ENST00000418533.2
LTBP1

latent transforming growth factor beta binding protein 1

chr11_+_35211429 0.727 ENST00000525688.1
ENST00000278385.6
ENST00000533222.1
CD44


CD44 molecule (Indian blood group)


chr2_+_74120094 0.726 ENST00000409731.3
ENST00000345517.3
ENST00000409918.1
ENST00000442912.1
ENST00000409624.1
ACTG2




actin, gamma 2, smooth muscle, enteric




chr3_+_183892635 0.723 ENST00000427072.1
ENST00000411763.2
ENST00000292807.5
ENST00000448139.1
ENST00000455925.1
AP2M1




adaptor-related protein complex 2, mu 1 subunit




chrX_+_135251835 0.720 ENST00000456445.1
FHL1
four and a half LIM domains 1
chr12_+_75874460 0.718 ENST00000266659.3
GLIPR1
GLI pathogenesis-related 1
chr19_-_43702231 0.715 ENST00000597374.1
ENST00000599371.1
PSG4

pregnancy specific beta-1-glycoprotein 4

chr1_-_145039949 0.710 ENST00000313382.9
PDE4DIP
phosphodiesterase 4D interacting protein
chr11_+_35198118 0.703 ENST00000525211.1
ENST00000526000.1
ENST00000279452.6
ENST00000527889.1
CD44



CD44 molecule (Indian blood group)



chr4_-_111544254 0.689 ENST00000306732.3
PITX2
paired-like homeodomain 2
chr12_+_26348429 0.686 ENST00000242729.2
SSPN
sarcospan
chr3_+_159570722 0.683 ENST00000482804.1
SCHIP1
schwannomin interacting protein 1
chr12_+_75874580 0.677 ENST00000456650.3
GLIPR1
GLI pathogenesis-related 1
chr15_+_43809797 0.676 ENST00000399453.1
ENST00000300231.5
MAP1A

microtubule-associated protein 1A

chrX_-_92928557 0.663 ENST00000373079.3
ENST00000475430.2
NAP1L3

nucleosome assembly protein 1-like 3

chr10_-_90712520 0.655 ENST00000224784.6
ACTA2
actin, alpha 2, smooth muscle, aorta
chr3_+_35722487 0.644 ENST00000441454.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr1_-_144995002 0.643 ENST00000369356.4
PDE4DIP
phosphodiesterase 4D interacting protein
chr8_-_120685608 0.638 ENST00000427067.2
ENPP2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr1_-_155211065 0.632 ENST00000427500.3
GBA
glucosidase, beta, acid
chr11_-_27723158 0.629 ENST00000395980.2
BDNF
brain-derived neurotrophic factor
chr8_-_49833978 0.624 ENST00000020945.1
SNAI2
snail family zinc finger 2
chr2_-_37899323 0.624 ENST00000295324.3
ENST00000457889.1
CDC42EP3

CDC42 effector protein (Rho GTPase binding) 3

chr3_-_52488048 0.612 ENST00000232975.3
TNNC1
troponin C type 1 (slow)
chr1_-_145039771 0.598 ENST00000493130.2
ENST00000532801.1
ENST00000478649.2
PDE4DIP


phosphodiesterase 4D interacting protein


chr16_+_31044413 0.594 ENST00000394998.1
STX4
syntaxin 4
chr5_+_82767583 0.592 ENST00000512590.2
ENST00000513960.1
ENST00000513984.1
ENST00000502527.2
VCAN



versican



chr21_+_40823753 0.587 ENST00000333634.4
SH3BGR
SH3 domain binding glutamic acid-rich protein
chr11_+_131240373 0.587 ENST00000374791.3
ENST00000436745.1
NTM

neurotrimin

chr1_+_158978768 0.584 ENST00000447473.2
IFI16
interferon, gamma-inducible protein 16
chr5_-_175843524 0.567 ENST00000502877.1
CLTB
clathrin, light chain B
chrX_+_51636629 0.555 ENST00000375722.1
ENST00000326587.7
ENST00000375695.2
MAGED1


melanoma antigen family D, 1


chr12_+_1738363 0.551 ENST00000397196.2
WNT5B
wingless-type MMTV integration site family, member 5B
chr16_+_6533380 0.551 ENST00000552089.1
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr17_+_68165657 0.547 ENST00000243457.3
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr17_-_7297833 0.540 ENST00000571802.1
ENST00000576201.1
ENST00000573213.1
ENST00000324822.11
TMEM256-PLSCR3



TMEM256-PLSCR3 readthrough (NMD candidate)



chr15_+_67458357 0.535 ENST00000537194.2
SMAD3
SMAD family member 3
chr15_+_43803143 0.534 ENST00000382031.1
MAP1A
microtubule-associated protein 1A
chr1_-_144995074 0.532 ENST00000534536.1
PDE4DIP
phosphodiesterase 4D interacting protein
chr13_-_33780133 0.525 ENST00000399365.3
STARD13
StAR-related lipid transfer (START) domain containing 13
chr1_-_201476274 0.522 ENST00000340006.2
CSRP1
cysteine and glycine-rich protein 1
chr3_+_158787041 0.519 ENST00000471575.1
ENST00000476809.1
ENST00000485419.1
IQCJ-SCHIP1


IQCJ-SCHIP1 readthrough


chr17_-_53809473 0.515 ENST00000575734.1
TMEM100
transmembrane protein 100
chr7_+_90338712 0.489 ENST00000265741.3
ENST00000406263.1
CDK14

cyclin-dependent kinase 14

chr11_-_85780853 0.483 ENST00000531930.1
ENST00000528398.1
PICALM

phosphatidylinositol binding clathrin assembly protein

chr17_+_16318850 0.480 ENST00000338560.7
TRPV2
transient receptor potential cation channel, subfamily V, member 2
chr5_+_140864649 0.478 ENST00000306593.1
PCDHGC4
protocadherin gamma subfamily C, 4
chr3_+_49449636 0.478 ENST00000273590.3
TCTA
T-cell leukemia translocation altered
chr6_+_39760129 0.473 ENST00000274867.4
DAAM2
dishevelled associated activator of morphogenesis 2
chr15_+_68924327 0.472 ENST00000543950.1
CORO2B
coronin, actin binding protein, 2B
chr2_-_218808771 0.466 ENST00000449814.1
ENST00000171887.4
TNS1

tensin 1

chr5_+_34757309 0.462 ENST00000397449.1
RAI14
retinoic acid induced 14
chr10_-_70287231 0.460 ENST00000609923.1
SLC25A16
solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16
chrX_+_65384052 0.459 ENST00000336279.5
ENST00000458621.1
HEPH

hephaestin

chr1_-_144994909 0.454 ENST00000369347.4
ENST00000369354.3
PDE4DIP

phosphodiesterase 4D interacting protein

chr9_+_116263778 0.453 ENST00000394646.3
RGS3
regulator of G-protein signaling 3
chr5_+_140810132 0.451 ENST00000252085.3
PCDHGA12
protocadherin gamma subfamily A, 12
chr20_-_3996036 0.450 ENST00000336095.6
RNF24
ring finger protein 24
chr3_+_135741576 0.450 ENST00000334546.2
PPP2R3A
protein phosphatase 2, regulatory subunit B'', alpha
chr14_+_58666824 0.449 ENST00000254286.4
ACTR10
actin-related protein 10 homolog (S. cerevisiae)
chr17_+_16318909 0.442 ENST00000577397.1
TRPV2
transient receptor potential cation channel, subfamily V, member 2
chr12_+_58087901 0.435 ENST00000315970.7
ENST00000547079.1
ENST00000439210.2
ENST00000389146.6
ENST00000413095.2
ENST00000551035.1
ENST00000257966.8
ENST00000435406.2
ENST00000550372.1
ENST00000389142.5
OS9









osteosarcoma amplified 9, endoplasmic reticulum lectin









chr11_-_117186946 0.434 ENST00000313005.6
ENST00000528053.1
BACE1

beta-site APP-cleaving enzyme 1

chr11_+_12132117 0.433 ENST00000256194.4
MICAL2
microtubule associated monooxygenase, calponin and LIM domain containing 2
chr7_+_129932974 0.431 ENST00000445470.2
ENST00000222482.4
ENST00000492072.1
ENST00000473956.1
ENST00000493259.1
ENST00000486598.1
CPA4





carboxypeptidase A4





chr8_-_13372395 0.429 ENST00000276297.4
ENST00000511869.1
DLC1

deleted in liver cancer 1

chrX_+_65384182 0.421 ENST00000441993.2
ENST00000419594.1
HEPH

hephaestin

chr9_+_116263639 0.420 ENST00000343817.5
RGS3
regulator of G-protein signaling 3
chr7_+_120628731 0.419 ENST00000310396.5
CPED1
cadherin-like and PC-esterase domain containing 1
chr12_+_54422142 0.418 ENST00000243108.4
HOXC6
homeobox C6
chr5_-_175843569 0.415 ENST00000310418.4
ENST00000345807.2
CLTB

clathrin, light chain B

chr3_-_178789993 0.413 ENST00000432729.1
ZMAT3
zinc finger, matrin-type 3
chr19_-_55660561 0.412 ENST00000587758.1
ENST00000356783.5
ENST00000291901.8
ENST00000588426.1
ENST00000588147.1
ENST00000536926.1
ENST00000588981.1
TNNT1






troponin T type 1 (skeletal, slow)






chr5_+_155753745 0.411 ENST00000435422.3
ENST00000337851.4
ENST00000447401.1
SGCD


sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)


chr17_-_7145475 0.409 ENST00000571129.1
ENST00000571253.1
ENST00000573928.1
GABARAP


GABA(A) receptor-associated protein


chr9_+_82186872 0.405 ENST00000376544.3
ENST00000376520.4
TLE4

transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)

chr2_+_85360499 0.400 ENST00000282111.3
TCF7L1
transcription factor 7-like 1 (T-cell specific, HMG-box)
chr11_-_47470591 0.400 ENST00000524487.1
RAPSN
receptor-associated protein of the synapse
chr2_+_201170770 0.398 ENST00000409988.3
ENST00000409385.1
SPATS2L

spermatogenesis associated, serine-rich 2-like

chrX_-_51239425 0.396 ENST00000375992.3
NUDT11
nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr4_+_159593418 0.394 ENST00000507475.1
ENST00000307738.5
ETFDH

electron-transferring-flavoprotein dehydrogenase

chr1_-_145039835 0.392 ENST00000533259.1
PDE4DIP
phosphodiesterase 4D interacting protein
chr18_-_52989525 0.388 ENST00000457482.3
TCF4
transcription factor 4
chr5_-_54830784 0.382 ENST00000264775.5
PPAP2A
phosphatidic acid phosphatase type 2A
chr2_-_79315112 0.377 ENST00000305089.3
REG1B
regenerating islet-derived 1 beta
chr14_+_104029278 0.376 ENST00000409074.2
ENST00000440963.1
ENST00000556253.2
ENST00000247618.4
ENST00000472726.2
APOPT1



RP11-73M18.2
apoptogenic 1, mitochondrial



Kinesin light chain 1
chr1_+_101185290 0.375 ENST00000370119.4
ENST00000347652.2
ENST00000294728.2
ENST00000370115.1
VCAM1



vascular cell adhesion molecule 1



chr11_-_47470703 0.371 ENST00000298854.2
RAPSN
receptor-associated protein of the synapse
chr8_-_72987810 0.370 ENST00000262209.4
TRPA1
transient receptor potential cation channel, subfamily A, member 1
chrX_-_106243451 0.369 ENST00000355610.4
ENST00000535534.1
MORC4

MORC family CW-type zinc finger 4

chr3_-_88108212 0.367 ENST00000482016.1
CGGBP1
CGG triplet repeat binding protein 1
chr3_-_99594948 0.367 ENST00000471562.1
ENST00000495625.2
FILIP1L

filamin A interacting protein 1-like

chr2_+_192141611 0.366 ENST00000392316.1
MYO1B
myosin IB
chrX_+_100333709 0.364 ENST00000372930.4
TMEM35
transmembrane protein 35
chr2_+_24714729 0.359 ENST00000406961.1
ENST00000405141.1
NCOA1

nuclear receptor coactivator 1

chr4_+_87515454 0.355 ENST00000427191.2
ENST00000436978.1
ENST00000502971.1
PTPN13


protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)


chr9_-_13175823 0.355 ENST00000545857.1
MPDZ
multiple PDZ domain protein
chr7_+_73442422 0.353 ENST00000358929.4
ENST00000431562.1
ENST00000320492.7
ENST00000438906.1
ELN



elastin



chr14_+_90722886 0.353 ENST00000543772.2
PSMC1
proteasome (prosome, macropain) 26S subunit, ATPase, 1
chrX_+_73641286 0.352 ENST00000587091.1
SLC16A2
solute carrier family 16, member 2 (thyroid hormone transporter)
chr2_+_109237717 0.344 ENST00000409441.1
LIMS1
LIM and senescent cell antigen-like domains 1
chr7_-_76255444 0.343 ENST00000454397.1
POMZP3
POM121 and ZP3 fusion
chr3_-_52486841 0.340 ENST00000496590.1
TNNC1
troponin C type 1 (slow)
chr9_-_14180778 0.337 ENST00000380924.1
ENST00000543693.1
NFIB

nuclear factor I/B

chr10_-_49813090 0.335 ENST00000249601.4
ARHGAP22
Rho GTPase activating protein 22
chr7_+_73442487 0.329 ENST00000380575.4
ENST00000380584.4
ENST00000458204.1
ENST00000357036.5
ENST00000417091.1
ENST00000429192.1
ENST00000442310.1
ENST00000380553.4
ENST00000380576.5
ENST00000428787.1
ENST00000320399.6
ELN










elastin










chr11_-_47470682 0.328 ENST00000529341.1
ENST00000352508.3
RAPSN

receptor-associated protein of the synapse

chr7_+_98923505 0.327 ENST00000432884.2
ENST00000262942.5
ARPC1A

actin related protein 2/3 complex, subunit 1A, 41kDa

chr14_+_85996471 0.325 ENST00000330753.4
FLRT2
fibronectin leucine rich transmembrane protein 2
chr11_-_33744256 0.324 ENST00000415002.2
ENST00000437761.2
ENST00000445143.2
CD59


CD59 molecule, complement regulatory protein


chr1_-_93426998 0.321 ENST00000370310.4
FAM69A
family with sequence similarity 69, member A
chr2_-_152589670 0.319 ENST00000604864.1
ENST00000603639.1
NEB

nebulin

chr5_-_172756506 0.318 ENST00000265087.4
STC2
stanniocalcin 2
chr2_+_201173667 0.316 ENST00000409755.3
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr13_-_24463530 0.316 ENST00000382172.3
MIPEP
mitochondrial intermediate peptidase
chr18_+_54318566 0.314 ENST00000589935.1
ENST00000357574.3
WDR7

WD repeat domain 7

chr17_-_7297519 0.312 ENST00000576362.1
ENST00000571078.1
TMEM256-PLSCR3

TMEM256-PLSCR3 readthrough (NMD candidate)

chrX_+_55478538 0.311 ENST00000342972.1
MAGEH1
melanoma antigen family H, 1
chr3_-_99833333 0.311 ENST00000354552.3
ENST00000331335.5
ENST00000398326.2
FILIP1L


filamin A interacting protein 1-like


chr14_+_23340822 0.310 ENST00000359591.4
LRP10
low density lipoprotein receptor-related protein 10
chr8_+_97597148 0.307 ENST00000521590.1
SDC2
syndecan 2
chr19_-_36247910 0.306 ENST00000587965.1
ENST00000004982.3
HSPB6

heat shock protein, alpha-crystallin-related, B6

chr2_+_172544294 0.306 ENST00000358002.6
ENST00000435234.1
ENST00000443458.1
ENST00000412370.1
DYNC1I2



dynein, cytoplasmic 1, intermediate chain 2



chr19_-_49496557 0.304 ENST00000323798.3
ENST00000541188.1
ENST00000544287.1
ENST00000540532.1
ENST00000263276.6
GYS1




glycogen synthase 1 (muscle)




chr18_+_54318616 0.303 ENST00000254442.3
WDR7
WD repeat domain 7
chr14_+_90722839 0.302 ENST00000261303.8
ENST00000553835.1
PSMC1

proteasome (prosome, macropain) 26S subunit, ATPase, 1

chrX_-_15872914 0.301 ENST00000380291.1
ENST00000545766.1
ENST00000421527.2
ENST00000329235.2
AP1S2



adaptor-related protein complex 1, sigma 2 subunit



chr1_+_38022572 0.300 ENST00000541606.1
DNALI1
dynein, axonemal, light intermediate chain 1
chr2_-_128399706 0.300 ENST00000426981.1
LIMS2
LIM and senescent cell antigen-like domains 2
chrX_+_66764375 0.299 ENST00000374690.3
AR
androgen receptor
chr2_+_219081817 0.296 ENST00000315717.5
ENST00000420104.1
ENST00000295685.10
ARPC2


actin related protein 2/3 complex, subunit 2, 34kDa


chr4_-_7873981 0.296 ENST00000360265.4
AFAP1
actin filament associated protein 1
chr11_+_65686952 0.290 ENST00000527119.1
DRAP1
DR1-associated protein 1 (negative cofactor 2 alpha)
chr7_-_142247606 0.287 ENST00000390361.3
TRBV7-3
T cell receptor beta variable 7-3
chr3_+_54157480 0.287 ENST00000490478.1
CACNA2D3
calcium channel, voltage-dependent, alpha 2/delta subunit 3
chr2_+_192109911 0.286 ENST00000418908.1
ENST00000339514.4
ENST00000392318.3
MYO1B


myosin IB


chr4_+_113739244 0.285 ENST00000503271.1
ENST00000503423.1
ENST00000506722.1
ANK2


ankyrin 2, neuronal


chr17_-_29648761 0.284 ENST00000247270.3
ENST00000462804.2
EVI2A

ecotropic viral integration site 2A

chr19_-_45826125 0.282 ENST00000221476.3
CKM
creatine kinase, muscle
chr1_-_244013384 0.282 ENST00000366539.1
AKT3
v-akt murine thymoma viral oncogene homolog 3
chr7_+_120629653 0.281 ENST00000450913.2
ENST00000340646.5
CPED1

cadherin-like and PC-esterase domain containing 1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 0.4 GO:0016573 internal protein amino acid acetylation(GO:0006475) histone acetylation(GO:0016573) internal peptidyl-lysine acetylation(GO:0018393) peptidyl-lysine acetylation(GO:0018394)
0.4 1.5 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
0.3 1.0 GO:1903115 regulation of muscle filament sliding(GO:0032971) regulation of actin filament-based movement(GO:1903115)
0.3 1.2 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.3 1.7 GO:2000124 cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926) regulation of endocannabinoid signaling pathway(GO:2000124)
0.3 0.6 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.3 0.8 GO:0031034 skeletal muscle myosin thick filament assembly(GO:0030241) myosin filament assembly(GO:0031034) striated muscle myosin thick filament assembly(GO:0071688)
0.3 0.8 GO:2000121 regulation of removal of superoxide radicals(GO:2000121)
0.3 2.0 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.3 3.5 GO:1901797 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.2 0.2 GO:0003350 pulmonary myocardium development(GO:0003350)
0.2 1.4 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.2 0.9 GO:0043116 negative regulation of vascular permeability(GO:0043116)
0.2 0.4 GO:0048319 axial mesoderm morphogenesis(GO:0048319)
0.2 0.7 GO:0021569 rhombomere 3 development(GO:0021569)
0.2 1.5 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.2 1.4 GO:0071692 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1 0.3 GO:0090598 male genitalia morphogenesis(GO:0048808) lateral sprouting involved in mammary gland duct morphogenesis(GO:0060599) male anatomical structure morphogenesis(GO:0090598)
0.1 0.4 GO:0051013 microtubule severing(GO:0051013)
0.1 0.9 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 0.4 GO:0050968 detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.1 0.3 GO:0046931 pore complex assembly(GO:0046931)
0.1 0.3 GO:0032242 regulation of nucleoside transport(GO:0032242) regulation of neurotrophin production(GO:0032899) negative regulation of neurotrophin production(GO:0032900) negative regulation of vasodilation(GO:0045908)
0.1 0.3 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.1 0.5 GO:0014819 regulation of skeletal muscle contraction(GO:0014819)
0.1 0.5 GO:0044413 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.1 1.2 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.1 0.4 GO:0008354 germ cell migration(GO:0008354)
0.1 2.0 GO:0008347 glial cell migration(GO:0008347)
0.1 1.7 GO:0030199 collagen fibril organization(GO:0030199)
0.1 0.3 GO:0042262 DNA protection(GO:0042262)
0.1 0.4 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 1.8 GO:0042730 fibrinolysis(GO:0042730)
0.1 0.2 GO:0050758 thymidylate synthase biosynthetic process(GO:0050757) regulation of thymidylate synthase biosynthetic process(GO:0050758) negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.1 0.2 GO:0006740 NADPH regeneration(GO:0006740)
0.1 0.4 GO:0022614 membrane to membrane docking(GO:0022614) chorio-allantoic fusion(GO:0060710)
0.1 0.7 GO:0048261 negative regulation of receptor-mediated endocytosis(GO:0048261)
0.1 5.0 GO:0009408 response to heat(GO:0009408)
0.1 0.8 GO:0060638 mesenchymal-epithelial cell signaling(GO:0060638)
0.1 0.3 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.2 GO:2000858 renin-angiotensin regulation of aldosterone production(GO:0002018) regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072) positive regulation of NAD(P)H oxidase activity(GO:0033864) mineralocorticoid secretion(GO:0035931) aldosterone secretion(GO:0035932) regulation of mineralocorticoid secretion(GO:2000855) regulation of aldosterone secretion(GO:2000858)
0.1 0.1 GO:0042118 endothelial cell activation(GO:0042118)
0.1 0.3 GO:0007525 somatic muscle development(GO:0007525)
0.1 0.2 GO:0033364 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510) mast cell secretory granule organization(GO:0033364)
0.1 0.1 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0 0.1 GO:0070781 response to biotin(GO:0070781)
0.0 0.1 GO:1903960 negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.0 1.6 GO:0060048 cardiac muscle contraction(GO:0060048)
0.0 0.5 GO:0006942 regulation of striated muscle contraction(GO:0006942)
0.0 0.4 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.0 0.3 GO:0032801 receptor catabolic process(GO:0032801)
0.0 0.5 GO:0006621 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0 0.1 GO:0014002 astrocyte development(GO:0014002)
0.0 0.8 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.4 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.0 0.4 GO:0045932 negative regulation of muscle contraction(GO:0045932)
0.0 0.2 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0 0.2 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 0.2 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 2.3 GO:0006892 post-Golgi vesicle-mediated transport(GO:0006892)
0.0 0.4 GO:0014003 oligodendrocyte development(GO:0014003)
0.0 0.1 GO:1902913 positive regulation of neuroepithelial cell differentiation(GO:1902913)
0.0 0.5 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.2 GO:0032236 obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0 1.1 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.2 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.1 GO:0043587 tongue morphogenesis(GO:0043587)
0.0 0.1 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.0 0.1 GO:0046520 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520)
0.0 0.1 GO:0034310 primary alcohol catabolic process(GO:0034310)
0.0 0.4 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 0.1 GO:0031558 obsolete induction of apoptosis in response to chemical stimulus(GO:0031558)
0.0 0.0 GO:0003078 obsolete regulation of natriuresis(GO:0003078)
0.0 0.2 GO:0019934 cGMP-mediated signaling(GO:0019934)
0.0 0.5 GO:0044349 nucleotide-excision repair, DNA damage removal(GO:0000718) DNA excision(GO:0044349)
0.0 0.4 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.3 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.2 GO:0032472 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) Golgi calcium ion transport(GO:0032472) manganese ion homeostasis(GO:0055071)
0.0 0.1 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.1 GO:0090047 retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299) obsolete positive regulation of transcription regulator activity(GO:0090047)
0.0 0.8 GO:0001755 neural crest cell migration(GO:0001755)
0.0 0.1 GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.0 0.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:0044321 cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321) negative regulation of gluconeogenesis(GO:0045721)
0.0 0.2 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.0 GO:0010834 obsolete telomere maintenance via telomere shortening(GO:0010834)
0.0 0.8 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 1.2 GO:0051318 G1 phase(GO:0051318)
0.0 0.1 GO:0022417 protein maturation by protein folding(GO:0022417)
0.0 0.1 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.4 GO:0000303 response to superoxide(GO:0000303)
0.0 0.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.0 GO:0007632 visual behavior(GO:0007632)
0.0 0.1 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.8 GO:0009060 aerobic respiration(GO:0009060)
0.0 0.1 GO:0000212 meiotic spindle organization(GO:0000212)
0.0 0.1 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.3 GO:0031000 response to caffeine(GO:0031000)
0.0 0.4 GO:0043496 regulation of protein homodimerization activity(GO:0043496)
0.0 0.1 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.0 GO:0002281 macrophage activation involved in immune response(GO:0002281)
0.0 0.1 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.2 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.2 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 2.2 GO:0065004 protein-DNA complex assembly(GO:0065004)
0.0 0.1 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.0 0.1 GO:0005984 disaccharide metabolic process(GO:0005984)
0.0 1.1 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.1 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.0 0.2 GO:0009148 GTP biosynthetic process(GO:0006183) UTP biosynthetic process(GO:0006228) CTP biosynthetic process(GO:0006241) pyrimidine nucleoside triphosphate biosynthetic process(GO:0009148) pyrimidine ribonucleoside triphosphate metabolic process(GO:0009208) pyrimidine ribonucleoside triphosphate biosynthetic process(GO:0009209) CTP metabolic process(GO:0046036) UTP metabolic process(GO:0046051)
0.0 0.5 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 0.2 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.2 GO:0051927 obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051927)
0.0 0.5 GO:0007368 determination of left/right symmetry(GO:0007368)
0.0 1.0 GO:0006826 iron ion transport(GO:0006826)
0.0 0.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.0 GO:0035269 protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502)
0.0 0.6 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.5 GO:0007566 embryo implantation(GO:0007566)
0.0 0.1 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.0 0.2 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.0 GO:0046469 platelet activating factor biosynthetic process(GO:0006663) platelet activating factor metabolic process(GO:0046469)
0.0 0.2 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 0.2 GO:0030166 proteoglycan biosynthetic process(GO:0030166)
0.0 0.2 GO:0008634 obsolete negative regulation of survival gene product expression(GO:0008634)
0.0 0.1 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.2 GO:1904031 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0 0.1 GO:0015074 DNA integration(GO:0015074)
0.0 0.1 GO:0006216 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0 0.2 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.3 GO:0006084 acetyl-CoA metabolic process(GO:0006084)
0.0 0.1 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.1 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.0 0.1 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.2 GO:0007520 myoblast fusion(GO:0007520)
0.0 1.5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.1 GO:0045329 amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.0 2.6 GO:0006936 muscle contraction(GO:0006936)
0.0 0.1 GO:0000710 meiotic mismatch repair(GO:0000710)
0.0 0.1 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.3 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.1 GO:0061756 leukocyte tethering or rolling(GO:0050901) leukocyte adhesion to vascular endothelial cell(GO:0061756)
0.0 0.1 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.0 0.0 GO:0051102 DNA ligation involved in DNA recombination(GO:0051102)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0071953 elastic fiber(GO:0071953)
0.2 0.5 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 1.7 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.4 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.1 1.4 GO:0001950 obsolete plasma membrane enriched fraction(GO:0001950)
0.1 2.5 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.1 0.4 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.1 0.6 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 0.7 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 1.6 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 0.6 GO:0031430 M band(GO:0031430)
0.1 0.3 GO:0005955 calcineurin complex(GO:0005955)
0.1 1.6 GO:0005861 troponin complex(GO:0005861)
0.1 0.4 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.1 0.6 GO:0005869 dynactin complex(GO:0005869)
0.1 0.3 GO:0016939 kinesin II complex(GO:0016939)
0.1 1.8 GO:0005859 muscle myosin complex(GO:0005859)
0.1 0.8 GO:0000421 autophagosome membrane(GO:0000421)
0.1 0.6 GO:0005678 obsolete chromatin assembly complex(GO:0005678)
0.0 0.3 GO:0098984 asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0 0.2 GO:0031045 dense core granule(GO:0031045) clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 2.0 GO:0098636 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.5 GO:0005858 axonemal dynein complex(GO:0005858) axoneme part(GO:0044447)
0.0 0.9 GO:0031105 septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 0.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.5 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.4 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 1.9 GO:0016459 myosin complex(GO:0016459)
0.0 0.4 GO:0005675 holo TFIIH complex(GO:0005675)
0.0 0.9 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.2 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.3 GO:0061200 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0 0.1 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.2 GO:0042587 glycogen granule(GO:0042587)
0.0 0.3 GO:0022624 proteasome regulatory particle(GO:0005838) proteasome accessory complex(GO:0022624)
0.0 0.2 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.0 0.1 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.2 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.5 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.0 GO:0071817 MMXD complex(GO:0071817)
0.0 2.3 GO:0030016 myofibril(GO:0030016)
0.0 0.1 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.1 GO:0030897 HOPS complex(GO:0030897)
0.0 0.0 GO:0031501 mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.2 GO:0071203 WASH complex(GO:0071203)
0.0 0.1 GO:0005602 complement component C1 complex(GO:0005602)
0.0 0.4 GO:1990204 oxidoreductase complex(GO:1990204)
0.0 1.1 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.5 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.2 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.4 GO:0030286 dynein complex(GO:0030286)
0.0 0.2 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.5 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.6 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.3 GO:0005811 lipid particle(GO:0005811)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.4 1.6 GO:0004348 glucosylceramidase activity(GO:0004348)
0.2 2.0 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.2 5.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 0.7 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.2 2.0 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, RNA polymerase II basal transcription factor binding(GO:0001083) transcription factor activity, TFIIB-class binding(GO:0001087) RNA polymerase II basal transcription factor binding(GO:0001091) TFIIB-class transcription factor binding(GO:0001093)
0.2 0.9 GO:0097493 extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.1 3.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 1.7 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 1.0 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.1 0.6 GO:0045545 syndecan binding(GO:0045545)
0.1 1.4 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.1 0.4 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 0.4 GO:0048039 ubiquinone binding(GO:0048039)
0.1 1.4 GO:0031014 troponin T binding(GO:0031014)
0.1 0.3 GO:0000150 recombinase activity(GO:0000150)
0.1 0.5 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 0.3 GO:0030611 arsenate reductase activity(GO:0030611)
0.1 0.3 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.1 0.9 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.3 GO:0050816 beta-2 adrenergic receptor binding(GO:0031698) phosphothreonine binding(GO:0050816)
0.1 0.4 GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.1 0.2 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.1 0.8 GO:0051393 alpha-actinin binding(GO:0051393)
0.1 0.7 GO:0050811 GABA receptor binding(GO:0050811)
0.1 0.4 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 0.2 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.1 0.2 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.1 0.3 GO:0004882 androgen receptor activity(GO:0004882)
0.1 0.3 GO:0004111 creatine kinase activity(GO:0004111)
0.1 0.5 GO:0005110 frizzled-2 binding(GO:0005110)
0.1 0.4 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.1 1.9 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.1 1.5 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 0.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 0.4 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.4 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.4 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 1.4 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 0.2 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.4 GO:0005536 glucose binding(GO:0005536)
0.0 0.2 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.0 0.2 GO:0019961 interferon binding(GO:0019961)
0.0 0.2 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328) N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.0 0.2 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.2 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.0 0.1 GO:0004473 malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.0 0.8 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.7 GO:0070064 proline-rich region binding(GO:0070064)
0.0 1.1 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.3 GO:0030172 troponin C binding(GO:0030172)
0.0 0.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.5 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.2 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.1 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 1.5 GO:0005518 collagen binding(GO:0005518)
0.0 0.4 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.2 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.0 0.5 GO:0030332 cyclin binding(GO:0030332)
0.0 0.7 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.4 GO:0004437 obsolete inositol or phosphatidylinositol phosphatase activity(GO:0004437)
0.0 0.1 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.1 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.4 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 1.0 GO:1990782 receptor tyrosine kinase binding(GO:0030971) protein tyrosine kinase binding(GO:1990782)
0.0 0.1 GO:0000827 inositol-1,3,4,5,6-pentakisphosphate kinase activity(GO:0000827) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.1 GO:0004738 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.1 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 1.0 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 0.1 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.1 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.1 GO:0045030 UTP-activated nucleotide receptor activity(GO:0045030)
0.0 0.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.1 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.0 0.4 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 1.6 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.2 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.2 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.0 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.0 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.4 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.4 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 1.1 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.0 GO:0008480 sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.0 0.1 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.1 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.0 0.3 GO:0019894 kinesin binding(GO:0019894)
0.0 0.0 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0 0.7 GO:0019208 phosphatase regulator activity(GO:0019208)
0.0 0.1 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.1 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 1.2 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.0 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.1 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.0 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.0 0.0 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.8 GO:0015297 antiporter activity(GO:0015297)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.0 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.0 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 2.5 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 0.8 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.2 ST_ADRENERGIC Adrenergic Pathway
0.0 0.2 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 0.3 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.