Motif ID: MEIS1
Z-value: 1.070
Transcription factors associated with MEIS1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
MEIS1 | ENSG00000143995.15 | MEIS1 |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 0.4 | GO:0016573 | internal protein amino acid acetylation(GO:0006475) histone acetylation(GO:0016573) internal peptidyl-lysine acetylation(GO:0018393) peptidyl-lysine acetylation(GO:0018394) |
0.4 | 1.5 | GO:0002689 | negative regulation of leukocyte chemotaxis(GO:0002689) |
0.3 | 1.0 | GO:1903115 | regulation of muscle filament sliding(GO:0032971) regulation of actin filament-based movement(GO:1903115) |
0.3 | 1.2 | GO:0090244 | Wnt signaling pathway involved in somitogenesis(GO:0090244) |
0.3 | 1.7 | GO:2000124 | cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926) regulation of endocannabinoid signaling pathway(GO:2000124) |
0.3 | 0.6 | GO:0060028 | convergent extension involved in axis elongation(GO:0060028) |
0.3 | 0.8 | GO:0031034 | skeletal muscle myosin thick filament assembly(GO:0030241) myosin filament assembly(GO:0031034) striated muscle myosin thick filament assembly(GO:0071688) |
0.3 | 0.8 | GO:2000121 | regulation of removal of superoxide radicals(GO:2000121) |
0.3 | 2.0 | GO:0007185 | transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185) |
0.3 | 3.5 | GO:1901797 | negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797) |
0.2 | 0.2 | GO:0003350 | pulmonary myocardium development(GO:0003350) |
0.2 | 1.4 | GO:0007499 | ectoderm and mesoderm interaction(GO:0007499) |
0.2 | 0.9 | GO:0043116 | negative regulation of vascular permeability(GO:0043116) |
0.2 | 0.4 | GO:0048319 | axial mesoderm morphogenesis(GO:0048319) |
0.2 | 0.7 | GO:0021569 | rhombomere 3 development(GO:0021569) |
0.2 | 1.5 | GO:0034638 | phosphatidylcholine catabolic process(GO:0034638) |
0.2 | 1.4 | GO:0071692 | sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116) |
0.1 | 0.3 | GO:0090598 | male genitalia morphogenesis(GO:0048808) lateral sprouting involved in mammary gland duct morphogenesis(GO:0060599) male anatomical structure morphogenesis(GO:0090598) |
0.1 | 0.4 | GO:0051013 | microtubule severing(GO:0051013) |
0.1 | 0.9 | GO:0060666 | dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666) |
0.1 | 0.4 | GO:0050968 | detection of chemical stimulus involved in sensory perception of pain(GO:0050968) |
0.1 | 0.3 | GO:0046931 | pore complex assembly(GO:0046931) |
0.1 | 0.3 | GO:0032242 | regulation of nucleoside transport(GO:0032242) regulation of neurotrophin production(GO:0032899) negative regulation of neurotrophin production(GO:0032900) negative regulation of vasodilation(GO:0045908) |
0.1 | 0.3 | GO:0046586 | regulation of calcium-dependent cell-cell adhesion(GO:0046586) |
0.1 | 0.5 | GO:0014819 | regulation of skeletal muscle contraction(GO:0014819) |
0.1 | 0.5 | GO:0044413 | evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834) |
0.1 | 1.2 | GO:0032331 | negative regulation of chondrocyte differentiation(GO:0032331) |
0.1 | 0.4 | GO:0008354 | germ cell migration(GO:0008354) |
0.1 | 2.0 | GO:0008347 | glial cell migration(GO:0008347) |
0.1 | 1.7 | GO:0030199 | collagen fibril organization(GO:0030199) |
0.1 | 0.3 | GO:0042262 | DNA protection(GO:0042262) |
0.1 | 0.4 | GO:0033539 | fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539) |
0.1 | 1.8 | GO:0042730 | fibrinolysis(GO:0042730) |
0.1 | 0.2 | GO:0050758 | thymidylate synthase biosynthetic process(GO:0050757) regulation of thymidylate synthase biosynthetic process(GO:0050758) negative regulation of thymidylate synthase biosynthetic process(GO:0050760) |
0.1 | 0.2 | GO:0006740 | NADPH regeneration(GO:0006740) |
0.1 | 0.4 | GO:0022614 | membrane to membrane docking(GO:0022614) chorio-allantoic fusion(GO:0060710) |
0.1 | 0.7 | GO:0048261 | negative regulation of receptor-mediated endocytosis(GO:0048261) |
0.1 | 5.0 | GO:0009408 | response to heat(GO:0009408) |
0.1 | 0.8 | GO:0060638 | mesenchymal-epithelial cell signaling(GO:0060638) |
0.1 | 0.3 | GO:0007221 | positive regulation of transcription of Notch receptor target(GO:0007221) |
0.1 | 0.2 | GO:2000858 | renin-angiotensin regulation of aldosterone production(GO:0002018) regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072) positive regulation of NAD(P)H oxidase activity(GO:0033864) mineralocorticoid secretion(GO:0035931) aldosterone secretion(GO:0035932) regulation of mineralocorticoid secretion(GO:2000855) regulation of aldosterone secretion(GO:2000858) |
0.1 | 0.1 | GO:0042118 | endothelial cell activation(GO:0042118) |
0.1 | 0.3 | GO:0007525 | somatic muscle development(GO:0007525) |
0.1 | 0.2 | GO:0033364 | endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510) mast cell secretory granule organization(GO:0033364) |
0.1 | 0.1 | GO:0032509 | endosome transport via multivesicular body sorting pathway(GO:0032509) |
0.0 | 0.1 | GO:0070781 | response to biotin(GO:0070781) |
0.0 | 0.1 | GO:1903960 | negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192) |
0.0 | 1.6 | GO:0060048 | cardiac muscle contraction(GO:0060048) |
0.0 | 0.5 | GO:0006942 | regulation of striated muscle contraction(GO:0006942) |
0.0 | 0.4 | GO:0050435 | beta-amyloid metabolic process(GO:0050435) |
0.0 | 0.3 | GO:0032801 | receptor catabolic process(GO:0032801) |
0.0 | 0.5 | GO:0006621 | protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437) |
0.0 | 0.1 | GO:0014002 | astrocyte development(GO:0014002) |
0.0 | 0.8 | GO:0032012 | regulation of ARF protein signal transduction(GO:0032012) |
0.0 | 0.4 | GO:0009263 | deoxyribonucleotide biosynthetic process(GO:0009263) |
0.0 | 0.4 | GO:0045932 | negative regulation of muscle contraction(GO:0045932) |
0.0 | 0.2 | GO:0006436 | tryptophanyl-tRNA aminoacylation(GO:0006436) |
0.0 | 0.2 | GO:0043001 | Golgi to plasma membrane protein transport(GO:0043001) |
0.0 | 0.2 | GO:0006295 | nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295) |
0.0 | 2.3 | GO:0006892 | post-Golgi vesicle-mediated transport(GO:0006892) |
0.0 | 0.4 | GO:0014003 | oligodendrocyte development(GO:0014003) |
0.0 | 0.1 | GO:1902913 | positive regulation of neuroepithelial cell differentiation(GO:1902913) |
0.0 | 0.5 | GO:0015939 | pantothenate metabolic process(GO:0015939) |
0.0 | 0.2 | GO:0032236 | obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236) |
0.0 | 1.1 | GO:0080171 | lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171) |
0.0 | 0.2 | GO:0035455 | response to interferon-alpha(GO:0035455) |
0.0 | 0.1 | GO:0043587 | tongue morphogenesis(GO:0043587) |
0.0 | 0.1 | GO:0051823 | regulation of synapse structural plasticity(GO:0051823) |
0.0 | 0.1 | GO:0046520 | diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520) |
0.0 | 0.1 | GO:0034310 | primary alcohol catabolic process(GO:0034310) |
0.0 | 0.4 | GO:0051496 | positive regulation of stress fiber assembly(GO:0051496) |
0.0 | 0.1 | GO:0031558 | obsolete induction of apoptosis in response to chemical stimulus(GO:0031558) |
0.0 | 0.0 | GO:0003078 | obsolete regulation of natriuresis(GO:0003078) |
0.0 | 0.2 | GO:0019934 | cGMP-mediated signaling(GO:0019934) |
0.0 | 0.5 | GO:0044349 | nucleotide-excision repair, DNA damage removal(GO:0000718) DNA excision(GO:0044349) |
0.0 | 0.4 | GO:0070536 | protein K63-linked deubiquitination(GO:0070536) |
0.0 | 0.3 | GO:0006600 | creatine metabolic process(GO:0006600) |
0.0 | 0.2 | GO:0032472 | cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) Golgi calcium ion transport(GO:0032472) manganese ion homeostasis(GO:0055071) |
0.0 | 0.1 | GO:0046007 | negative regulation of activated T cell proliferation(GO:0046007) |
0.0 | 0.1 | GO:0090047 | retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299) obsolete positive regulation of transcription regulator activity(GO:0090047) |
0.0 | 0.8 | GO:0001755 | neural crest cell migration(GO:0001755) |
0.0 | 0.1 | GO:0060831 | smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831) |
0.0 | 0.2 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
0.0 | 0.1 | GO:0044321 | cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321) negative regulation of gluconeogenesis(GO:0045721) |
0.0 | 0.2 | GO:0035162 | embryonic hemopoiesis(GO:0035162) |
0.0 | 0.0 | GO:0010834 | obsolete telomere maintenance via telomere shortening(GO:0010834) |
0.0 | 0.8 | GO:0050690 | regulation of defense response to virus by virus(GO:0050690) |
0.0 | 1.2 | GO:0051318 | G1 phase(GO:0051318) |
0.0 | 0.1 | GO:0022417 | protein maturation by protein folding(GO:0022417) |
0.0 | 0.1 | GO:0018344 | protein geranylgeranylation(GO:0018344) |
0.0 | 0.4 | GO:0000303 | response to superoxide(GO:0000303) |
0.0 | 0.1 | GO:0043569 | negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569) |
0.0 | 0.0 | GO:0007632 | visual behavior(GO:0007632) |
0.0 | 0.1 | GO:0000301 | retrograde transport, vesicle recycling within Golgi(GO:0000301) |
0.0 | 0.8 | GO:0009060 | aerobic respiration(GO:0009060) |
0.0 | 0.1 | GO:0000212 | meiotic spindle organization(GO:0000212) |
0.0 | 0.1 | GO:0001514 | selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451) |
0.0 | 0.3 | GO:0031000 | response to caffeine(GO:0031000) |
0.0 | 0.4 | GO:0043496 | regulation of protein homodimerization activity(GO:0043496) |
0.0 | 0.1 | GO:0007217 | tachykinin receptor signaling pathway(GO:0007217) |
0.0 | 0.0 | GO:0002281 | macrophage activation involved in immune response(GO:0002281) |
0.0 | 0.1 | GO:0046856 | phosphatidylinositol dephosphorylation(GO:0046856) |
0.0 | 0.2 | GO:0090292 | nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292) |
0.0 | 0.2 | GO:0015014 | heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014) |
0.0 | 2.2 | GO:0065004 | protein-DNA complex assembly(GO:0065004) |
0.0 | 0.1 | GO:0032781 | positive regulation of ATPase activity(GO:0032781) |
0.0 | 0.1 | GO:0005984 | disaccharide metabolic process(GO:0005984) |
0.0 | 1.1 | GO:0045454 | cell redox homeostasis(GO:0045454) |
0.0 | 0.1 | GO:0042074 | cell migration involved in gastrulation(GO:0042074) |
0.0 | 0.2 | GO:0009148 | GTP biosynthetic process(GO:0006183) UTP biosynthetic process(GO:0006228) CTP biosynthetic process(GO:0006241) pyrimidine nucleoside triphosphate biosynthetic process(GO:0009148) pyrimidine ribonucleoside triphosphate metabolic process(GO:0009208) pyrimidine ribonucleoside triphosphate biosynthetic process(GO:0009209) CTP metabolic process(GO:0046036) UTP metabolic process(GO:0046051) |
0.0 | 0.5 | GO:0042771 | intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771) |
0.0 | 0.2 | GO:0051457 | maintenance of protein location in nucleus(GO:0051457) |
0.0 | 0.2 | GO:0051927 | obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051927) |
0.0 | 0.5 | GO:0007368 | determination of left/right symmetry(GO:0007368) |
0.0 | 1.0 | GO:0006826 | iron ion transport(GO:0006826) |
0.0 | 0.1 | GO:0001672 | regulation of chromatin assembly or disassembly(GO:0001672) |
0.0 | 0.0 | GO:0035269 | protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502) |
0.0 | 0.6 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
0.0 | 0.5 | GO:0007566 | embryo implantation(GO:0007566) |
0.0 | 0.1 | GO:0042483 | negative regulation of odontogenesis(GO:0042483) |
0.0 | 0.2 | GO:0030321 | transepithelial chloride transport(GO:0030321) |
0.0 | 0.0 | GO:0046469 | platelet activating factor biosynthetic process(GO:0006663) platelet activating factor metabolic process(GO:0046469) |
0.0 | 0.2 | GO:0033138 | positive regulation of peptidyl-serine phosphorylation(GO:0033138) |
0.0 | 0.2 | GO:0030166 | proteoglycan biosynthetic process(GO:0030166) |
0.0 | 0.2 | GO:0008634 | obsolete negative regulation of survival gene product expression(GO:0008634) |
0.0 | 0.1 | GO:0006020 | inositol metabolic process(GO:0006020) |
0.0 | 0.2 | GO:1904031 | positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031) |
0.0 | 0.1 | GO:0015074 | DNA integration(GO:0015074) |
0.0 | 0.1 | GO:0006216 | cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087) |
0.0 | 0.2 | GO:0000381 | regulation of alternative mRNA splicing, via spliceosome(GO:0000381) |
0.0 | 0.3 | GO:0006084 | acetyl-CoA metabolic process(GO:0006084) |
0.0 | 0.1 | GO:0043982 | histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982) |
0.0 | 0.1 | GO:0031572 | G2 DNA damage checkpoint(GO:0031572) |
0.0 | 0.1 | GO:0017183 | peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) |
0.0 | 0.2 | GO:0007520 | myoblast fusion(GO:0007520) |
0.0 | 1.5 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
0.0 | 0.1 | GO:0045329 | amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329) |
0.0 | 2.6 | GO:0006936 | muscle contraction(GO:0006936) |
0.0 | 0.1 | GO:0000710 | meiotic mismatch repair(GO:0000710) |
0.0 | 0.1 | GO:0006196 | AMP catabolic process(GO:0006196) |
0.0 | 0.3 | GO:0005978 | glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250) |
0.0 | 0.1 | GO:0061756 | leukocyte tethering or rolling(GO:0050901) leukocyte adhesion to vascular endothelial cell(GO:0061756) |
0.0 | 0.1 | GO:0042178 | xenobiotic catabolic process(GO:0042178) |
0.0 | 0.0 | GO:0051102 | DNA ligation involved in DNA recombination(GO:0051102) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 0.8 | GO:0071953 | elastic fiber(GO:0071953) |
0.2 | 0.5 | GO:0000308 | cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308) |
0.1 | 1.7 | GO:0098643 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
0.1 | 0.4 | GO:0071065 | alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065) |
0.1 | 1.4 | GO:0001950 | obsolete plasma membrane enriched fraction(GO:0001950) |
0.1 | 2.5 | GO:0030132 | clathrin coat of coated pit(GO:0030132) |
0.1 | 0.4 | GO:0000153 | cytoplasmic ubiquitin ligase complex(GO:0000153) |
0.1 | 0.6 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
0.1 | 0.7 | GO:0016012 | sarcoglycan complex(GO:0016012) |
0.1 | 1.6 | GO:0016010 | dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665) |
0.1 | 0.6 | GO:0031430 | M band(GO:0031430) |
0.1 | 0.3 | GO:0005955 | calcineurin complex(GO:0005955) |
0.1 | 1.6 | GO:0005861 | troponin complex(GO:0005861) |
0.1 | 0.4 | GO:0031305 | integral component of mitochondrial inner membrane(GO:0031305) |
0.1 | 0.6 | GO:0005869 | dynactin complex(GO:0005869) |
0.1 | 0.3 | GO:0016939 | kinesin II complex(GO:0016939) |
0.1 | 1.8 | GO:0005859 | muscle myosin complex(GO:0005859) |
0.1 | 0.8 | GO:0000421 | autophagosome membrane(GO:0000421) |
0.1 | 0.6 | GO:0005678 | obsolete chromatin assembly complex(GO:0005678) |
0.0 | 0.3 | GO:0098984 | asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984) |
0.0 | 0.2 | GO:0031045 | dense core granule(GO:0031045) clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201) |
0.0 | 2.0 | GO:0098636 | integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636) |
0.0 | 0.5 | GO:0005858 | axonemal dynein complex(GO:0005858) axoneme part(GO:0044447) |
0.0 | 0.9 | GO:0031105 | septin complex(GO:0031105) septin cytoskeleton(GO:0032156) |
0.0 | 0.2 | GO:0070695 | FHF complex(GO:0070695) |
0.0 | 0.3 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
0.0 | 0.1 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
0.0 | 0.5 | GO:0016471 | vacuolar proton-transporting V-type ATPase complex(GO:0016471) |
0.0 | 0.4 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
0.0 | 1.9 | GO:0016459 | myosin complex(GO:0016459) |
0.0 | 0.4 | GO:0005675 | holo TFIIH complex(GO:0005675) |
0.0 | 0.9 | GO:0031594 | neuromuscular junction(GO:0031594) |
0.0 | 0.2 | GO:0008537 | proteasome activator complex(GO:0008537) |
0.0 | 0.3 | GO:0061200 | clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202) |
0.0 | 0.1 | GO:0044295 | axonal growth cone(GO:0044295) |
0.0 | 0.2 | GO:0042587 | glycogen granule(GO:0042587) |
0.0 | 0.3 | GO:0022624 | proteasome regulatory particle(GO:0005838) proteasome accessory complex(GO:0022624) |
0.0 | 0.2 | GO:0000109 | nucleotide-excision repair complex(GO:0000109) |
0.0 | 0.1 | GO:0045254 | pyruvate dehydrogenase complex(GO:0045254) |
0.0 | 0.2 | GO:0042589 | zymogen granule membrane(GO:0042589) |
0.0 | 0.5 | GO:0030119 | AP-type membrane coat adaptor complex(GO:0030119) |
0.0 | 0.0 | GO:0071817 | MMXD complex(GO:0071817) |
0.0 | 2.3 | GO:0030016 | myofibril(GO:0030016) |
0.0 | 0.1 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
0.0 | 0.1 | GO:0030897 | HOPS complex(GO:0030897) |
0.0 | 0.0 | GO:0031501 | mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185) |
0.0 | 0.2 | GO:0071203 | WASH complex(GO:0071203) |
0.0 | 0.1 | GO:0005602 | complement component C1 complex(GO:0005602) |
0.0 | 0.4 | GO:1990204 | oxidoreductase complex(GO:1990204) |
0.0 | 1.1 | GO:0005802 | trans-Golgi network(GO:0005802) |
0.0 | 0.5 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
0.0 | 0.2 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
0.0 | 0.2 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
0.0 | 0.4 | GO:0030286 | dynein complex(GO:0030286) |
0.0 | 0.2 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
0.0 | 0.5 | GO:0005637 | nuclear inner membrane(GO:0005637) |
0.0 | 0.6 | GO:0005905 | clathrin-coated pit(GO:0005905) |
0.0 | 0.3 | GO:0005811 | lipid particle(GO:0005811) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 1.6 | GO:0047391 | alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391) |
0.4 | 1.6 | GO:0004348 | glucosylceramidase activity(GO:0004348) |
0.2 | 2.0 | GO:0005006 | epidermal growth factor-activated receptor activity(GO:0005006) |
0.2 | 5.7 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
0.2 | 0.7 | GO:0032050 | clathrin heavy chain binding(GO:0032050) |
0.2 | 2.0 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, RNA polymerase II basal transcription factor binding(GO:0001083) transcription factor activity, TFIIB-class binding(GO:0001087) RNA polymerase II basal transcription factor binding(GO:0001091) TFIIB-class transcription factor binding(GO:0001093) |
0.2 | 0.9 | GO:0097493 | extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493) |
0.1 | 3.8 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
0.1 | 1.7 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
0.1 | 1.0 | GO:0033130 | acetylcholine receptor binding(GO:0033130) |
0.1 | 0.6 | GO:0045545 | syndecan binding(GO:0045545) |
0.1 | 1.4 | GO:0050750 | low-density lipoprotein particle receptor binding(GO:0050750) |
0.1 | 0.4 | GO:0061731 | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731) |
0.1 | 0.4 | GO:0048039 | ubiquinone binding(GO:0048039) |
0.1 | 1.4 | GO:0031014 | troponin T binding(GO:0031014) |
0.1 | 0.3 | GO:0000150 | recombinase activity(GO:0000150) |
0.1 | 0.5 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
0.1 | 0.3 | GO:0030611 | arsenate reductase activity(GO:0030611) |
0.1 | 0.3 | GO:0032795 | heterotrimeric G-protein binding(GO:0032795) |
0.1 | 0.9 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
0.1 | 0.3 | GO:0050816 | beta-2 adrenergic receptor binding(GO:0031698) phosphothreonine binding(GO:0050816) |
0.1 | 0.4 | GO:0008486 | diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) |
0.1 | 0.2 | GO:0001596 | angiotensin type I receptor activity(GO:0001596) |
0.1 | 0.8 | GO:0051393 | alpha-actinin binding(GO:0051393) |
0.1 | 0.7 | GO:0050811 | GABA receptor binding(GO:0050811) |
0.1 | 0.4 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
0.1 | 0.2 | GO:0004345 | glucose-6-phosphate dehydrogenase activity(GO:0004345) |
0.1 | 0.2 | GO:0050698 | proteoglycan sulfotransferase activity(GO:0050698) |
0.1 | 0.3 | GO:0004882 | androgen receptor activity(GO:0004882) |
0.1 | 0.3 | GO:0004111 | creatine kinase activity(GO:0004111) |
0.1 | 0.5 | GO:0005110 | frizzled-2 binding(GO:0005110) |
0.1 | 0.4 | GO:0042392 | sphingosine-1-phosphate phosphatase activity(GO:0042392) |
0.1 | 1.9 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
0.1 | 1.5 | GO:0005484 | SNAP receptor activity(GO:0005484) |
0.1 | 0.4 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
0.1 | 0.4 | GO:0008013 | beta-catenin binding(GO:0008013) |
0.0 | 0.4 | GO:0015349 | thyroid hormone transmembrane transporter activity(GO:0015349) |
0.0 | 0.4 | GO:0030346 | protein phosphatase 2B binding(GO:0030346) |
0.0 | 1.4 | GO:0005024 | transforming growth factor beta-activated receptor activity(GO:0005024) |
0.0 | 0.2 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
0.0 | 0.4 | GO:0005536 | glucose binding(GO:0005536) |
0.0 | 0.2 | GO:0008599 | protein phosphatase type 1 regulator activity(GO:0008599) |
0.0 | 0.2 | GO:0019961 | interferon binding(GO:0019961) |
0.0 | 0.2 | GO:0042328 | heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328) N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509) |
0.0 | 0.2 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
0.0 | 0.2 | GO:0004830 | tryptophan-tRNA ligase activity(GO:0004830) |
0.0 | 0.1 | GO:0004473 | malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) |
0.0 | 0.8 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
0.0 | 0.7 | GO:0070064 | proline-rich region binding(GO:0070064) |
0.0 | 1.1 | GO:0015035 | protein disulfide oxidoreductase activity(GO:0015035) |
0.0 | 0.3 | GO:0030172 | troponin C binding(GO:0030172) |
0.0 | 0.3 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
0.0 | 0.5 | GO:0005041 | low-density lipoprotein receptor activity(GO:0005041) |
0.0 | 0.2 | GO:0010859 | calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859) |
0.0 | 0.1 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
0.0 | 1.5 | GO:0005518 | collagen binding(GO:0005518) |
0.0 | 0.4 | GO:0004190 | aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001) |
0.0 | 0.2 | GO:0015410 | manganese-transporting ATPase activity(GO:0015410) |
0.0 | 0.5 | GO:0030332 | cyclin binding(GO:0030332) |
0.0 | 0.7 | GO:0005242 | inward rectifier potassium channel activity(GO:0005242) |
0.0 | 0.4 | GO:0004437 | obsolete inositol or phosphatidylinositol phosphatase activity(GO:0004437) |
0.0 | 0.1 | GO:0016623 | oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623) |
0.0 | 0.1 | GO:0008336 | gamma-butyrobetaine dioxygenase activity(GO:0008336) |
0.0 | 0.4 | GO:0005521 | lamin binding(GO:0005521) |
0.0 | 0.1 | GO:0017040 | ceramidase activity(GO:0017040) |
0.0 | 1.0 | GO:1990782 | receptor tyrosine kinase binding(GO:0030971) protein tyrosine kinase binding(GO:1990782) |
0.0 | 0.1 | GO:0000827 | inositol-1,3,4,5,6-pentakisphosphate kinase activity(GO:0000827) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857) |
0.0 | 0.1 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
0.0 | 0.7 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
0.0 | 0.1 | GO:0004738 | pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739) |
0.0 | 0.1 | GO:0070530 | K63-linked polyubiquitin binding(GO:0070530) |
0.0 | 1.0 | GO:0017048 | Rho GTPase binding(GO:0017048) |
0.0 | 0.1 | GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding(GO:0005546) |
0.0 | 0.1 | GO:0004703 | G-protein coupled receptor kinase activity(GO:0004703) |
0.0 | 0.1 | GO:0045030 | UTP-activated nucleotide receptor activity(GO:0045030) |
0.0 | 0.1 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
0.0 | 0.1 | GO:0019992 | diacylglycerol binding(GO:0019992) |
0.0 | 0.1 | GO:0048406 | nerve growth factor binding(GO:0048406) |
0.0 | 0.1 | GO:0033858 | N-acetylgalactosamine kinase activity(GO:0033858) |
0.0 | 0.4 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
0.0 | 1.6 | GO:0005262 | calcium channel activity(GO:0005262) |
0.0 | 0.2 | GO:0000014 | single-stranded DNA endodeoxyribonuclease activity(GO:0000014) |
0.0 | 0.1 | GO:0004800 | thyroxine 5'-deiodinase activity(GO:0004800) |
0.0 | 0.2 | GO:0004550 | nucleoside diphosphate kinase activity(GO:0004550) |
0.0 | 0.0 | GO:0016309 | 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309) |
0.0 | 0.0 | GO:0004582 | dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582) |
0.0 | 0.4 | GO:0008656 | cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656) |
0.0 | 0.4 | GO:0005001 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
0.0 | 1.1 | GO:0008307 | structural constituent of muscle(GO:0008307) |
0.0 | 0.0 | GO:0008480 | sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997) |
0.0 | 0.1 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
0.0 | 0.1 | GO:0004991 | parathyroid hormone receptor activity(GO:0004991) |
0.0 | 0.3 | GO:0019894 | kinesin binding(GO:0019894) |
0.0 | 0.0 | GO:0004439 | phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439) |
0.0 | 0.7 | GO:0019208 | phosphatase regulator activity(GO:0019208) |
0.0 | 0.1 | GO:0004105 | choline-phosphate cytidylyltransferase activity(GO:0004105) |
0.0 | 0.1 | GO:0004126 | cytidine deaminase activity(GO:0004126) |
0.0 | 0.1 | GO:0004955 | prostaglandin receptor activity(GO:0004955) |
0.0 | 1.2 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
0.0 | 0.0 | GO:0004016 | adenylate cyclase activity(GO:0004016) |
0.0 | 0.1 | GO:0004925 | prolactin receptor activity(GO:0004925) |
0.0 | 0.1 | GO:0046935 | 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935) |
0.0 | 0.0 | GO:0019763 | immunoglobulin receptor activity(GO:0019763) |
0.0 | 0.0 | GO:0005412 | glucose:sodium symporter activity(GO:0005412) |
0.0 | 0.8 | GO:0015297 | antiporter activity(GO:0015297) |
0.0 | 0.1 | GO:0004430 | 1-phosphatidylinositol 4-kinase activity(GO:0004430) |
0.0 | 0.0 | GO:0047184 | 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 3.0 | SA_MMP_CYTOKINE_CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
0.1 | 2.5 | ST_WNT_BETA_CATENIN_PATHWAY | Wnt/beta-catenin Pathway |
0.0 | 0.8 | ST_MYOCYTE_AD_PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
0.0 | 0.2 | ST_ADRENERGIC | Adrenergic Pathway |
0.0 | 0.2 | ST_G_ALPHA_S_PATHWAY | G alpha s Pathway |
0.0 | 0.3 | SA_PROGRAMMED_CELL_DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |