Motif ID: MEIS3_TGIF2LX
Z-value: 0.955
Transcription factors associated with MEIS3_TGIF2LX:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
MEIS3 | ENSG00000105419.13 | MEIS3 |
TGIF2LX | ENSG00000153779.8 | TGIF2LX |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 1.4 | GO:1902116 | negative regulation of organelle assembly(GO:1902116) |
0.2 | 0.8 | GO:0042118 | endothelial cell activation(GO:0042118) |
0.2 | 0.5 | GO:1901522 | positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522) |
0.1 | 1.3 | GO:0031017 | exocrine pancreas development(GO:0031017) |
0.1 | 0.4 | GO:0010727 | negative regulation of hydrogen peroxide metabolic process(GO:0010727) |
0.1 | 0.5 | GO:0009450 | gamma-aminobutyric acid catabolic process(GO:0009450) |
0.1 | 0.3 | GO:0001514 | selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451) |
0.0 | 1.0 | GO:0009812 | flavonoid metabolic process(GO:0009812) |
0.0 | 0.2 | GO:0060746 | maternal behavior(GO:0042711) parental behavior(GO:0060746) |
0.0 | 0.4 | GO:0006600 | creatine metabolic process(GO:0006600) |
0.0 | 0.3 | GO:0010739 | positive regulation of protein kinase A signaling(GO:0010739) |
0.0 | 0.2 | GO:0018106 | peptidyl-histidine phosphorylation(GO:0018106) |
0.0 | 1.8 | GO:0006749 | glutathione metabolic process(GO:0006749) |
0.0 | 0.1 | GO:0034723 | DNA replication-dependent nucleosome organization(GO:0034723) |
0.0 | 0.2 | GO:0051895 | negative regulation of focal adhesion assembly(GO:0051895) negative regulation of cell junction assembly(GO:1901889) negative regulation of adherens junction organization(GO:1903392) |
0.0 | 0.4 | GO:0032098 | regulation of appetite(GO:0032098) |
0.0 | 0.3 | GO:0050832 | defense response to fungus(GO:0050832) |
0.0 | 0.1 | GO:0070244 | negative regulation of thymocyte apoptotic process(GO:0070244) |
0.0 | 0.6 | GO:0050690 | regulation of defense response to virus by virus(GO:0050690) |
0.0 | 0.2 | GO:1901224 | B cell homeostasis(GO:0001782) activation of NF-kappaB-inducing kinase activity(GO:0007250) NIK/NF-kappaB signaling(GO:0038061) regulation of NIK/NF-kappaB signaling(GO:1901222) positive regulation of NIK/NF-kappaB signaling(GO:1901224) |
0.0 | 0.0 | GO:0015917 | aminophospholipid transport(GO:0015917) |
0.0 | 0.1 | GO:0015705 | iodide transport(GO:0015705) |
0.0 | 0.1 | GO:0030212 | hyaluronan metabolic process(GO:0030212) |
0.0 | 0.1 | GO:0071480 | cellular response to gamma radiation(GO:0071480) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 1.4 | GO:0042598 | obsolete vesicular fraction(GO:0042598) |
0.1 | 0.4 | GO:0031838 | haptoglobin-hemoglobin complex(GO:0031838) |
0.0 | 0.3 | GO:0045179 | apical cortex(GO:0045179) |
0.0 | 0.2 | GO:0042584 | chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584) |
0.0 | 0.2 | GO:0060171 | stereocilium membrane(GO:0060171) |
0.0 | 0.3 | GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex(GO:0031464) |
0.0 | 0.3 | GO:0016012 | sarcoglycan complex(GO:0016012) |
0.0 | 0.2 | GO:0042589 | zymogen granule membrane(GO:0042589) |
0.0 | 0.8 | GO:0043195 | terminal bouton(GO:0043195) |
0.0 | 0.2 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
0.0 | 0.1 | GO:0005826 | actomyosin contractile ring(GO:0005826) |
0.0 | 0.4 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
0.0 | 0.1 | GO:0016585 | obsolete chromatin remodeling complex(GO:0016585) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 0.6 | GO:0052593 | tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596) |
0.1 | 0.3 | GO:0005329 | dopamine transmembrane transporter activity(GO:0005329) |
0.1 | 1.4 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
0.1 | 0.4 | GO:0004111 | creatine kinase activity(GO:0004111) |
0.1 | 0.8 | GO:0035381 | extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) |
0.1 | 1.0 | GO:0004062 | aryl sulfotransferase activity(GO:0004062) |
0.1 | 0.4 | GO:0030492 | hemoglobin binding(GO:0030492) |
0.1 | 1.9 | GO:0004364 | glutathione transferase activity(GO:0004364) |
0.1 | 0.3 | GO:0004800 | thyroxine 5'-deiodinase activity(GO:0004800) |
0.0 | 0.6 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, RNA polymerase II basal transcription factor binding(GO:0001083) transcription factor activity, TFIIB-class binding(GO:0001087) RNA polymerase II basal transcription factor binding(GO:0001091) TFIIB-class transcription factor binding(GO:0001093) |
0.0 | 0.3 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
0.0 | 0.2 | GO:0004740 | pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740) |
0.0 | 1.3 | GO:0005159 | insulin-like growth factor receptor binding(GO:0005159) |
0.0 | 0.2 | GO:0016715 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715) |
0.0 | 0.6 | GO:0050786 | RAGE receptor binding(GO:0050786) |
0.0 | 0.3 | GO:0004176 | ATP-dependent peptidase activity(GO:0004176) |
0.0 | 0.2 | GO:0004185 | serine-type carboxypeptidase activity(GO:0004185) |
0.0 | 0.1 | GO:0004030 | aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030) |
0.0 | 0.2 | GO:0016004 | phospholipase activator activity(GO:0016004) |
0.0 | 0.3 | GO:0004887 | thyroid hormone receptor activity(GO:0004887) |
0.0 | 0.5 | GO:0004806 | triglyceride lipase activity(GO:0004806) |
0.0 | 0.2 | GO:0030172 | troponin C binding(GO:0030172) |
0.0 | 0.0 | GO:0015247 | aminophospholipid transporter activity(GO:0015247) |
0.0 | 0.1 | GO:0043208 | glycosphingolipid binding(GO:0043208) |
0.0 | 0.4 | GO:0016620 | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 1.4 | ST_MYOCYTE_AD_PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |