Motif ID: MIXL1_GSX1_BSX_MEOX2_LHX4
Z-value: 1.834
Transcription factors associated with MIXL1_GSX1_BSX_MEOX2_LHX4:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| BSX | ENSG00000188909.4 | BSX |
| GSX1 | ENSG00000169840.4 | GSX1 |
| LHX4 | ENSG00000121454.4 | LHX4 |
| MEOX2 | ENSG00000106511.5 | MEOX2 |
| MIXL1 | ENSG00000185155.7 | MIXL1 |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.1 | 12.5 | GO:0060649 | nipple development(GO:0060618) mammary gland bud elongation(GO:0060649) nipple morphogenesis(GO:0060658) nipple sheath formation(GO:0060659) |
| 1.3 | 7.7 | GO:0007499 | ectoderm and mesoderm interaction(GO:0007499) |
| 0.8 | 2.5 | GO:0014029 | neural crest formation(GO:0014029) neural crest cell fate commitment(GO:0014034) convergent extension involved in axis elongation(GO:0060028) response to heparin(GO:0071503) cellular response to heparin(GO:0071504) negative regulation of non-canonical Wnt signaling pathway(GO:2000051) |
| 0.8 | 3.1 | GO:0090161 | Golgi ribbon formation(GO:0090161) |
| 0.7 | 1.4 | GO:0022600 | digestive system process(GO:0022600) intestinal absorption(GO:0050892) |
| 0.5 | 3.2 | GO:0006880 | intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577) |
| 0.5 | 2.3 | GO:0006789 | bilirubin conjugation(GO:0006789) biphenyl metabolic process(GO:0018879) biphenyl catabolic process(GO:0070980) |
| 0.4 | 2.6 | GO:0032472 | cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) Golgi calcium ion transport(GO:0032472) manganese ion homeostasis(GO:0055071) |
| 0.4 | 2.6 | GO:0002903 | negative regulation of B cell apoptotic process(GO:0002903) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192) |
| 0.4 | 0.8 | GO:0032641 | lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109) |
| 0.4 | 2.1 | GO:0043402 | glucocorticoid mediated signaling pathway(GO:0043402) |
| 0.4 | 1.4 | GO:0071418 | uroporphyrinogen III biosynthetic process(GO:0006780) cellular response to amine stimulus(GO:0071418) |
| 0.3 | 1.4 | GO:0031223 | auditory behavior(GO:0031223) malate-aspartate shuttle(GO:0043490) |
| 0.3 | 0.9 | GO:0046520 | diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520) |
| 0.3 | 2.2 | GO:0045116 | protein neddylation(GO:0045116) |
| 0.3 | 1.5 | GO:0015722 | canalicular bile acid transport(GO:0015722) pyrimidine nucleobase transport(GO:0015855) |
| 0.3 | 1.3 | GO:0050862 | positive regulation of T cell receptor signaling pathway(GO:0050862) |
| 0.2 | 1.0 | GO:0002072 | optic cup morphogenesis involved in camera-type eye development(GO:0002072) |
| 0.2 | 0.9 | GO:0043653 | mitochondrial fragmentation involved in apoptotic process(GO:0043653) |
| 0.2 | 5.6 | GO:0045103 | intermediate filament-based process(GO:0045103) |
| 0.2 | 0.8 | GO:0006668 | sphinganine-1-phosphate metabolic process(GO:0006668) |
| 0.2 | 4.2 | GO:0002504 | antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504) |
| 0.2 | 0.7 | GO:0070303 | negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of JNK cascade(GO:0046329) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303) |
| 0.2 | 0.7 | GO:0034310 | primary alcohol catabolic process(GO:0034310) |
| 0.2 | 0.7 | GO:1904037 | positive regulation of epithelial cell apoptotic process(GO:1904037) positive regulation of endothelial cell apoptotic process(GO:2000353) |
| 0.2 | 0.8 | GO:0071392 | cellular response to estradiol stimulus(GO:0071392) |
| 0.2 | 1.1 | GO:0043415 | positive regulation of skeletal muscle tissue regeneration(GO:0043415) regulation of skeletal muscle tissue regeneration(GO:0043416) |
| 0.2 | 1.4 | GO:0032528 | microvillus assembly(GO:0030033) microvillus organization(GO:0032528) |
| 0.1 | 0.4 | GO:0006543 | glutamine catabolic process(GO:0006543) |
| 0.1 | 0.4 | GO:0019731 | antibacterial humoral response(GO:0019731) |
| 0.1 | 0.6 | GO:1902414 | protein localization to adherens junction(GO:0071896) protein localization to cell junction(GO:1902414) |
| 0.1 | 0.7 | GO:0051611 | negative regulation of neurotransmitter uptake(GO:0051581) negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495) |
| 0.1 | 1.2 | GO:0002553 | histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553) |
| 0.1 | 0.5 | GO:0051547 | regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549) |
| 0.1 | 0.8 | GO:0042113 | B cell activation(GO:0042113) |
| 0.1 | 0.1 | GO:0002431 | Fc receptor mediated stimulatory signaling pathway(GO:0002431) regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369) |
| 0.1 | 0.6 | GO:0051902 | negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180) |
| 0.1 | 6.7 | GO:0071260 | cellular response to mechanical stimulus(GO:0071260) |
| 0.1 | 0.8 | GO:0042693 | muscle cell fate commitment(GO:0042693) |
| 0.1 | 0.2 | GO:0060972 | left/right pattern formation(GO:0060972) |
| 0.1 | 0.3 | GO:0002538 | arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540) cellular response to calcium ion(GO:0071277) |
| 0.1 | 0.3 | GO:0070989 | oxidative demethylation(GO:0070989) |
| 0.1 | 0.3 | GO:0035987 | endodermal cell fate commitment(GO:0001711) endodermal cell differentiation(GO:0035987) |
| 0.1 | 0.6 | GO:0007352 | zygotic specification of dorsal/ventral axis(GO:0007352) |
| 0.1 | 0.2 | GO:0045852 | pH elevation(GO:0045852) intracellular pH elevation(GO:0051454) |
| 0.1 | 0.5 | GO:0009750 | response to fructose(GO:0009750) |
| 0.1 | 0.6 | GO:1901503 | ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503) |
| 0.1 | 0.4 | GO:0019371 | cyclooxygenase pathway(GO:0019371) |
| 0.1 | 0.3 | GO:0090047 | obsolete positive regulation of transcription regulator activity(GO:0090047) |
| 0.1 | 0.4 | GO:0006556 | S-adenosylmethionine biosynthetic process(GO:0006556) |
| 0.1 | 0.6 | GO:0010224 | response to UV-B(GO:0010224) |
| 0.1 | 2.2 | GO:0006493 | protein O-linked glycosylation(GO:0006493) |
| 0.1 | 2.7 | GO:0033574 | response to testosterone(GO:0033574) |
| 0.1 | 0.3 | GO:0046621 | negative regulation of organ growth(GO:0046621) |
| 0.1 | 0.7 | GO:0007635 | chemosensory behavior(GO:0007635) |
| 0.1 | 0.3 | GO:0021759 | globus pallidus development(GO:0021759) menarche(GO:0042696) |
| 0.1 | 0.5 | GO:0043497 | regulation of protein heterodimerization activity(GO:0043497) |
| 0.1 | 0.2 | GO:0021797 | forebrain anterior/posterior pattern specification(GO:0021797) |
| 0.1 | 0.2 | GO:0031214 | biomineral tissue development(GO:0031214) |
| 0.1 | 0.6 | GO:0042149 | cellular response to glucose starvation(GO:0042149) |
| 0.1 | 0.3 | GO:0001831 | trophectodermal cellular morphogenesis(GO:0001831) |
| 0.1 | 0.5 | GO:0016584 | nucleosome positioning(GO:0016584) |
| 0.1 | 0.7 | GO:0015074 | DNA integration(GO:0015074) |
| 0.1 | 0.2 | GO:0055062 | phosphate ion homeostasis(GO:0055062) divalent inorganic anion homeostasis(GO:0072505) trivalent inorganic anion homeostasis(GO:0072506) |
| 0.1 | 1.6 | GO:0033209 | tumor necrosis factor-mediated signaling pathway(GO:0033209) |
| 0.1 | 1.5 | GO:0006555 | methionine metabolic process(GO:0006555) |
| 0.1 | 0.3 | GO:0009235 | cobalamin metabolic process(GO:0009235) |
| 0.1 | 0.5 | GO:0060009 | Sertoli cell development(GO:0060009) |
| 0.1 | 1.0 | GO:0006906 | vesicle fusion(GO:0006906) |
| 0.1 | 0.2 | GO:0032226 | positive regulation of synaptic transmission, dopaminergic(GO:0032226) |
| 0.1 | 0.5 | GO:0060612 | adipose tissue development(GO:0060612) |
| 0.1 | 2.6 | GO:0090263 | positive regulation of canonical Wnt signaling pathway(GO:0090263) |
| 0.1 | 0.2 | GO:0010457 | centriole-centriole cohesion(GO:0010457) |
| 0.1 | 0.6 | GO:0045329 | amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329) |
| 0.1 | 0.2 | GO:0010966 | regulation of phosphate transport(GO:0010966) |
| 0.1 | 1.4 | GO:0030574 | collagen catabolic process(GO:0030574) |
| 0.1 | 0.6 | GO:0050858 | negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860) |
| 0.1 | 0.4 | GO:0035335 | peptidyl-tyrosine dephosphorylation(GO:0035335) |
| 0.1 | 0.3 | GO:0070172 | positive regulation of tooth mineralization(GO:0070172) |
| 0.1 | 0.6 | GO:0045741 | positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) |
| 0.1 | 0.3 | GO:0045176 | apical protein localization(GO:0045176) |
| 0.1 | 0.2 | GO:0002331 | immature B cell differentiation(GO:0002327) pre-B cell differentiation(GO:0002329) pre-B cell allelic exclusion(GO:0002331) |
| 0.1 | 0.3 | GO:0090084 | negative regulation of inclusion body assembly(GO:0090084) |
| 0.1 | 0.2 | GO:0007193 | adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193) |
| 0.1 | 0.3 | GO:0042905 | 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905) |
| 0.1 | 0.2 | GO:0019918 | peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918) |
| 0.0 | 0.2 | GO:0009438 | methylglyoxal metabolic process(GO:0009438) |
| 0.0 | 0.1 | GO:0048003 | antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) |
| 0.0 | 0.3 | GO:0043249 | erythrocyte maturation(GO:0043249) |
| 0.0 | 1.9 | GO:0006309 | DNA catabolic process, endonucleolytic(GO:0000737) apoptotic DNA fragmentation(GO:0006309) |
| 0.0 | 0.2 | GO:0002726 | positive regulation of T cell cytokine production(GO:0002726) |
| 0.0 | 0.0 | GO:0072677 | eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677) |
| 0.0 | 1.1 | GO:0071577 | zinc II ion transmembrane transport(GO:0071577) |
| 0.0 | 0.1 | GO:0018076 | N-terminal peptidyl-lysine acetylation(GO:0018076) |
| 0.0 | 1.1 | GO:0042776 | mitochondrial ATP synthesis coupled proton transport(GO:0042776) |
| 0.0 | 0.5 | GO:0034661 | ncRNA catabolic process(GO:0034661) |
| 0.0 | 0.6 | GO:0007507 | heart development(GO:0007507) |
| 0.0 | 0.1 | GO:0021913 | regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913) |
| 0.0 | 0.3 | GO:0007346 | regulation of mitotic cell cycle(GO:0007346) |
| 0.0 | 0.1 | GO:0048535 | lymph node development(GO:0048535) |
| 0.0 | 2.0 | GO:0048813 | dendrite morphogenesis(GO:0048813) |
| 0.0 | 0.3 | GO:0000098 | sulfur amino acid catabolic process(GO:0000098) |
| 0.0 | 6.0 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
| 0.0 | 0.1 | GO:0002282 | microglial cell activation involved in immune response(GO:0002282) |
| 0.0 | 0.3 | GO:0016098 | monoterpenoid metabolic process(GO:0016098) |
| 0.0 | 0.1 | GO:0010172 | embryonic body morphogenesis(GO:0010172) |
| 0.0 | 0.1 | GO:0051255 | spindle midzone assembly(GO:0051255) meiotic spindle midzone assembly(GO:0051257) |
| 0.0 | 1.1 | GO:0050909 | sensory perception of taste(GO:0050909) |
| 0.0 | 0.2 | GO:0001514 | selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451) |
| 0.0 | 0.3 | GO:0060665 | regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665) regulation of branching involved in salivary gland morphogenesis(GO:0060693) |
| 0.0 | 0.1 | GO:0010459 | negative regulation of heart rate(GO:0010459) |
| 0.0 | 0.5 | GO:0008272 | sulfate transport(GO:0008272) |
| 0.0 | 0.7 | GO:0030178 | negative regulation of Wnt signaling pathway(GO:0030178) |
| 0.0 | 0.6 | GO:0016601 | Rac protein signal transduction(GO:0016601) |
| 0.0 | 0.1 | GO:0043438 | acetoacetic acid metabolic process(GO:0043438) |
| 0.0 | 0.7 | GO:0031055 | DNA replication-independent nucleosome assembly(GO:0006336) chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) DNA replication-independent nucleosome organization(GO:0034724) CENP-A containing chromatin organization(GO:0061641) |
| 0.0 | 0.1 | GO:0071229 | cellular response to acid chemical(GO:0071229) |
| 0.0 | 0.2 | GO:0007258 | JUN phosphorylation(GO:0007258) |
| 0.0 | 0.6 | GO:0032924 | activin receptor signaling pathway(GO:0032924) |
| 0.0 | 0.5 | GO:0032008 | positive regulation of TOR signaling(GO:0032008) |
| 0.0 | 1.3 | GO:0007205 | protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205) |
| 0.0 | 1.0 | GO:0018149 | peptide cross-linking(GO:0018149) |
| 0.0 | 0.6 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
| 0.0 | 0.2 | GO:0002921 | negative regulation of humoral immune response(GO:0002921) negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258) |
| 0.0 | 0.2 | GO:0007185 | transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185) |
| 0.0 | 0.4 | GO:0045070 | positive regulation of viral genome replication(GO:0045070) |
| 0.0 | 0.2 | GO:0018345 | protein palmitoylation(GO:0018345) |
| 0.0 | 0.1 | GO:0007079 | mitotic chromosome movement towards spindle pole(GO:0007079) chromosome movement towards spindle pole(GO:0051305) |
| 0.0 | 0.3 | GO:0007603 | phototransduction, visible light(GO:0007603) |
| 0.0 | 0.4 | GO:0071482 | cellular response to light stimulus(GO:0071482) |
| 0.0 | 0.8 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.0 | 20.5 | GO:0007010 | cytoskeleton organization(GO:0007010) |
| 0.0 | 0.8 | GO:0043124 | negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124) |
| 0.0 | 0.4 | GO:0032456 | endocytic recycling(GO:0032456) |
| 0.0 | 0.1 | GO:0001780 | neutrophil homeostasis(GO:0001780) |
| 0.0 | 0.1 | GO:0051365 | cellular response to potassium ion starvation(GO:0051365) |
| 0.0 | 0.8 | GO:0007338 | single fertilization(GO:0007338) |
| 0.0 | 0.1 | GO:0000354 | cis assembly of pre-catalytic spliceosome(GO:0000354) |
| 0.0 | 0.2 | GO:0030520 | intracellular estrogen receptor signaling pathway(GO:0030520) |
| 0.0 | 0.1 | GO:0070544 | histone H3-K36 demethylation(GO:0070544) |
| 0.0 | 0.4 | GO:0042517 | positive regulation of tyrosine phosphorylation of Stat3 protein(GO:0042517) |
| 0.0 | 0.0 | GO:0006975 | DNA damage induced protein phosphorylation(GO:0006975) |
| 0.0 | 0.1 | GO:0006011 | UDP-glucose metabolic process(GO:0006011) UDP-glucuronate biosynthetic process(GO:0006065) |
| 0.0 | 0.1 | GO:0060025 | regulation of germinal center formation(GO:0002634) regulation of synaptic activity(GO:0060025) |
| 0.0 | 0.9 | GO:0030282 | bone mineralization(GO:0030282) |
| 0.0 | 0.1 | GO:0051552 | flavone metabolic process(GO:0051552) |
| 0.0 | 0.6 | GO:0034199 | activation of protein kinase A activity(GO:0034199) |
| 0.0 | 0.1 | GO:0015705 | iodide transport(GO:0015705) |
| 0.0 | 0.4 | GO:0007528 | neuromuscular junction development(GO:0007528) |
| 0.0 | 0.1 | GO:0030186 | melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187) |
| 0.0 | 0.6 | GO:0042771 | intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771) |
| 0.0 | 0.1 | GO:0018344 | protein geranylgeranylation(GO:0018344) |
| 0.0 | 0.2 | GO:0055091 | phospholipid homeostasis(GO:0055091) |
| 0.0 | 0.1 | GO:0018027 | peptidyl-lysine dimethylation(GO:0018027) |
| 0.0 | 0.2 | GO:0045008 | depyrimidination(GO:0045008) |
| 0.0 | 0.2 | GO:0042447 | hormone catabolic process(GO:0042447) |
| 0.0 | 0.1 | GO:0006726 | eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474) |
| 0.0 | 0.2 | GO:0006030 | chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032) |
| 0.0 | 0.1 | GO:0016926 | protein desumoylation(GO:0016926) |
| 0.0 | 0.1 | GO:0021516 | dorsal spinal cord development(GO:0021516) |
| 0.0 | 0.0 | GO:0032506 | mitotic cytokinesis(GO:0000281) barrier septum assembly(GO:0000917) cytokinetic process(GO:0032506) cell septum assembly(GO:0090529) mitotic cytokinetic process(GO:1902410) |
| 0.0 | 0.3 | GO:0000768 | syncytium formation by plasma membrane fusion(GO:0000768) myoblast fusion(GO:0007520) |
| 0.0 | 2.2 | GO:0007049 | cell cycle(GO:0007049) |
| 0.0 | 0.8 | GO:0000245 | spliceosomal complex assembly(GO:0000245) |
| 0.0 | 3.7 | GO:0007517 | muscle organ development(GO:0007517) |
| 0.0 | 0.2 | GO:0009887 | organ morphogenesis(GO:0009887) |
| 0.0 | 0.1 | GO:0060666 | dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666) |
| 0.0 | 0.3 | GO:0006596 | polyamine biosynthetic process(GO:0006596) |
| 0.0 | 0.0 | GO:0018874 | benzoate metabolic process(GO:0018874) |
| 0.0 | 0.1 | GO:0032331 | negative regulation of chondrocyte differentiation(GO:0032331) |
| 0.0 | 0.1 | GO:0006264 | mitochondrial DNA replication(GO:0006264) |
| 0.0 | 0.4 | GO:0051291 | protein heterooligomerization(GO:0051291) |
| 0.0 | 0.6 | GO:0016055 | Wnt signaling pathway(GO:0016055) cell-cell signaling by wnt(GO:0198738) |
| 0.0 | 0.0 | GO:0060259 | regulation of feeding behavior(GO:0060259) |
| 0.0 | 0.2 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 0.0 | 0.0 | GO:0048752 | semicircular canal morphogenesis(GO:0048752) |
| 0.0 | 0.1 | GO:0045003 | DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003) |
| 0.0 | 0.2 | GO:0007032 | endosome organization(GO:0007032) |
| 0.0 | 0.1 | GO:0035196 | production of miRNAs involved in gene silencing by miRNA(GO:0035196) |
| 0.0 | 0.3 | GO:0007257 | activation of JUN kinase activity(GO:0007257) |
| 0.0 | 0.1 | GO:0002230 | positive regulation of defense response to virus by host(GO:0002230) |
| 0.0 | 0.5 | GO:0006626 | protein targeting to mitochondrion(GO:0006626) |
| 0.0 | 0.2 | GO:0070830 | bicellular tight junction assembly(GO:0070830) |
| 0.0 | 0.2 | GO:0008347 | glial cell migration(GO:0008347) |
| 0.0 | 0.1 | GO:0007598 | blood coagulation, extrinsic pathway(GO:0007598) |
| 0.0 | 0.7 | GO:0006914 | autophagy(GO:0006914) |
| 0.0 | 1.7 | GO:0043123 | positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123) |
| 0.0 | 0.8 | GO:0048015 | phosphatidylinositol-mediated signaling(GO:0048015) inositol lipid-mediated signaling(GO:0048017) |
| 0.0 | 0.8 | GO:0006968 | cellular defense response(GO:0006968) |
| 0.0 | 2.6 | GO:0006936 | muscle contraction(GO:0006936) |
| 0.0 | 0.1 | GO:0006772 | thiamine metabolic process(GO:0006772) |
| 0.0 | 0.0 | GO:0000059 | protein import into nucleus, docking(GO:0000059) |
| 0.0 | 0.1 | GO:0045779 | negative regulation of bone resorption(GO:0045779) |
| 0.0 | 0.3 | GO:0045576 | mast cell activation(GO:0045576) |
| 0.0 | 0.2 | GO:0007595 | lactation(GO:0007595) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 17.3 | GO:0005884 | actin filament(GO:0005884) |
| 0.3 | 5.4 | GO:0031258 | lamellipodium membrane(GO:0031258) |
| 0.3 | 0.8 | GO:0000308 | cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308) |
| 0.2 | 1.4 | GO:0045179 | apical cortex(GO:0045179) |
| 0.2 | 4.2 | GO:0042613 | MHC class II protein complex(GO:0042613) |
| 0.2 | 0.9 | GO:0019718 | obsolete rough microsome(GO:0019718) |
| 0.2 | 6.5 | GO:0045095 | keratin filament(GO:0045095) |
| 0.1 | 3.5 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
| 0.1 | 0.5 | GO:0005863 | striated muscle myosin thick filament(GO:0005863) |
| 0.1 | 2.6 | GO:0043205 | fibril(GO:0043205) |
| 0.1 | 3.2 | GO:0030057 | desmosome(GO:0030057) |
| 0.1 | 0.8 | GO:0030056 | hemidesmosome(GO:0030056) |
| 0.1 | 0.2 | GO:0071438 | invadopodium membrane(GO:0071438) |
| 0.1 | 6.1 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.1 | 0.3 | GO:0005826 | actomyosin contractile ring(GO:0005826) |
| 0.1 | 1.6 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.1 | 0.2 | GO:0071986 | Ragulator complex(GO:0071986) |
| 0.1 | 0.2 | GO:0005588 | collagen type V trimer(GO:0005588) |
| 0.1 | 0.5 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) |
| 0.1 | 2.1 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 0.1 | 0.5 | GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex(GO:0005847) |
| 0.1 | 0.6 | GO:0033018 | sarcoplasmic reticulum lumen(GO:0033018) |
| 0.1 | 0.7 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
| 0.1 | 1.3 | GO:0042101 | T cell receptor complex(GO:0042101) |
| 0.1 | 1.4 | GO:0005689 | U12-type spliceosomal complex(GO:0005689) |
| 0.1 | 0.5 | GO:0030681 | nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681) |
| 0.1 | 0.6 | GO:0032040 | small-subunit processome(GO:0032040) |
| 0.1 | 1.1 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
| 0.1 | 0.5 | GO:0042598 | obsolete vesicular fraction(GO:0042598) |
| 0.0 | 0.1 | GO:0030669 | clathrin-coated endocytic vesicle membrane(GO:0030669) |
| 0.0 | 0.7 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.0 | 1.1 | GO:0045263 | proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263) |
| 0.0 | 0.1 | GO:0005674 | transcription factor TFIIF complex(GO:0005674) |
| 0.0 | 0.8 | GO:0032982 | myosin filament(GO:0032982) |
| 0.0 | 0.4 | GO:0030670 | phagocytic vesicle membrane(GO:0030670) |
| 0.0 | 0.3 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
| 0.0 | 0.3 | GO:0070852 | cell body fiber(GO:0070852) |
| 0.0 | 0.6 | GO:0008290 | F-actin capping protein complex(GO:0008290) |
| 0.0 | 0.4 | GO:0042824 | MHC class I peptide loading complex(GO:0042824) |
| 0.0 | 0.3 | GO:0005827 | polar microtubule(GO:0005827) |
| 0.0 | 3.5 | GO:0005802 | trans-Golgi network(GO:0005802) |
| 0.0 | 0.9 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.0 | 0.5 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 0.0 | 0.5 | GO:0016328 | lateral plasma membrane(GO:0016328) |
| 0.0 | 0.1 | GO:0005712 | chiasma(GO:0005712) MutLbeta complex(GO:0032390) |
| 0.0 | 0.1 | GO:0031205 | endoplasmic reticulum Sec complex(GO:0031205) |
| 0.0 | 0.4 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
| 0.0 | 4.2 | GO:0005769 | early endosome(GO:0005769) |
| 0.0 | 1.1 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.0 | 0.1 | GO:0032584 | growth cone membrane(GO:0032584) |
| 0.0 | 0.1 | GO:0005602 | complement component C1 complex(GO:0005602) |
| 0.0 | 0.1 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
| 0.0 | 0.2 | GO:0002102 | podosome(GO:0002102) |
| 0.0 | 7.0 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.0 | 0.7 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
| 0.0 | 0.4 | GO:0033116 | endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116) |
| 0.0 | 0.8 | GO:0030119 | AP-type membrane coat adaptor complex(GO:0030119) |
| 0.0 | 0.4 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
| 0.0 | 0.1 | GO:0030130 | clathrin coat of trans-Golgi network vesicle(GO:0030130) |
| 0.0 | 0.4 | GO:0034362 | low-density lipoprotein particle(GO:0034362) |
| 0.0 | 0.6 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.0 | 0.5 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 0.0 | 0.3 | GO:0000777 | condensed chromosome kinetochore(GO:0000777) |
| 0.0 | 0.3 | GO:0032589 | neuron projection membrane(GO:0032589) |
| 0.0 | 0.2 | GO:0042555 | MCM complex(GO:0042555) |
| 0.0 | 0.2 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
| 0.0 | 0.1 | GO:0015935 | small ribosomal subunit(GO:0015935) |
| 0.0 | 2.8 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.0 | 0.1 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
| 0.0 | 0.2 | GO:0071778 | obsolete WINAC complex(GO:0071778) |
| 0.0 | 0.7 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 0.0 | 2.5 | GO:0005925 | focal adhesion(GO:0005925) |
| 0.0 | 0.4 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.0 | 0.4 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.0 | 0.6 | GO:0005912 | adherens junction(GO:0005912) |
| 0.0 | 0.1 | GO:0045259 | mitochondrial proton-transporting ATP synthase complex(GO:0005753) proton-transporting ATP synthase complex(GO:0045259) |
| 0.0 | 0.2 | GO:0005626 | obsolete insoluble fraction(GO:0005626) |
| 0.0 | 0.6 | GO:0042734 | presynaptic membrane(GO:0042734) |
| 0.0 | 0.2 | GO:0008021 | synaptic vesicle(GO:0008021) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.7 | 16.1 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
| 1.8 | 8.9 | GO:0034597 | phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) phosphatidylinositol phosphate 4-phosphatase activity(GO:0034596) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) |
| 0.6 | 2.5 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
| 0.4 | 2.6 | GO:0015410 | manganese-transporting ATPase activity(GO:0015410) |
| 0.4 | 10.5 | GO:0045028 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
| 0.4 | 2.1 | GO:0004883 | glucocorticoid receptor activity(GO:0004883) |
| 0.4 | 1.5 | GO:0015254 | glycerol channel activity(GO:0015254) |
| 0.4 | 1.4 | GO:0005324 | long-chain fatty acid transporter activity(GO:0005324) |
| 0.4 | 1.4 | GO:0004852 | uroporphyrinogen-III synthase activity(GO:0004852) |
| 0.3 | 7.7 | GO:0008656 | cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656) |
| 0.2 | 1.0 | GO:0070324 | thyroid hormone binding(GO:0070324) |
| 0.2 | 2.0 | GO:0008113 | peptide-methionine (S)-S-oxide reductase activity(GO:0008113) |
| 0.2 | 0.7 | GO:0005223 | intracellular cGMP activated cation channel activity(GO:0005223) |
| 0.2 | 0.7 | GO:0005174 | CD40 receptor binding(GO:0005174) |
| 0.2 | 2.1 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
| 0.2 | 0.6 | GO:0050062 | long-chain-fatty-acyl-CoA reductase activity(GO:0050062) |
| 0.2 | 0.5 | GO:0036002 | pre-mRNA binding(GO:0036002) |
| 0.2 | 0.2 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.2 | 1.9 | GO:0008527 | taste receptor activity(GO:0008527) |
| 0.2 | 2.2 | GO:0008641 | small protein activating enzyme activity(GO:0008641) |
| 0.2 | 1.3 | GO:0046934 | phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813) |
| 0.2 | 2.4 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.1 | 0.9 | GO:0097493 | extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493) |
| 0.1 | 1.0 | GO:0030021 | extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345) |
| 0.1 | 0.6 | GO:0008336 | gamma-butyrobetaine dioxygenase activity(GO:0008336) |
| 0.1 | 1.4 | GO:0005314 | high-affinity glutamate transmembrane transporter activity(GO:0005314) |
| 0.1 | 0.7 | GO:0016623 | oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623) |
| 0.1 | 0.7 | GO:0060961 | phospholipase D inhibitor activity(GO:0060961) |
| 0.1 | 1.7 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, RNA polymerase II basal transcription factor binding(GO:0001083) transcription factor activity, TFIIB-class binding(GO:0001087) RNA polymerase II basal transcription factor binding(GO:0001091) TFIIB-class transcription factor binding(GO:0001093) |
| 0.1 | 0.4 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
| 0.1 | 0.8 | GO:0042392 | sphingosine-1-phosphate phosphatase activity(GO:0042392) |
| 0.1 | 0.7 | GO:0005499 | vitamin D binding(GO:0005499) |
| 0.1 | 0.4 | GO:0004359 | glutaminase activity(GO:0004359) |
| 0.1 | 0.4 | GO:0004083 | bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619) |
| 0.1 | 0.5 | GO:0004558 | alpha-1,4-glucosidase activity(GO:0004558) |
| 0.1 | 12.4 | GO:0005179 | hormone activity(GO:0005179) |
| 0.1 | 3.1 | GO:0001972 | retinoic acid binding(GO:0001972) |
| 0.1 | 1.4 | GO:0032395 | MHC class II receptor activity(GO:0032395) |
| 0.1 | 0.4 | GO:0004666 | prostaglandin-endoperoxide synthase activity(GO:0004666) |
| 0.1 | 0.6 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.1 | 0.3 | GO:0003858 | 3-hydroxybutyrate dehydrogenase activity(GO:0003858) |
| 0.1 | 1.6 | GO:0005031 | tumor necrosis factor-activated receptor activity(GO:0005031) |
| 0.1 | 1.1 | GO:0016409 | palmitoyltransferase activity(GO:0016409) |
| 0.1 | 0.8 | GO:0030172 | troponin C binding(GO:0030172) |
| 0.1 | 0.3 | GO:0008508 | bile acid:sodium symporter activity(GO:0008508) |
| 0.1 | 0.2 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
| 0.1 | 1.2 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.1 | 0.3 | GO:0034875 | oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875) |
| 0.1 | 2.6 | GO:0005158 | insulin receptor binding(GO:0005158) |
| 0.1 | 0.5 | GO:0030297 | transmembrane receptor protein tyrosine kinase activator activity(GO:0030297) |
| 0.1 | 0.5 | GO:0008271 | secondary active sulfate transmembrane transporter activity(GO:0008271) |
| 0.1 | 1.6 | GO:0005246 | calcium channel regulator activity(GO:0005246) |
| 0.1 | 1.1 | GO:0030332 | cyclin binding(GO:0030332) |
| 0.1 | 0.6 | GO:0015125 | bile acid transmembrane transporter activity(GO:0015125) |
| 0.1 | 1.1 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
| 0.1 | 1.4 | GO:0004143 | diacylglycerol kinase activity(GO:0004143) |
| 0.1 | 0.2 | GO:0008263 | pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263) |
| 0.1 | 0.9 | GO:0043236 | laminin binding(GO:0043236) |
| 0.1 | 0.8 | GO:0070888 | E-box binding(GO:0070888) |
| 0.1 | 0.2 | GO:0035243 | protein-arginine omega-N symmetric methyltransferase activity(GO:0035243) |
| 0.0 | 1.1 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.0 | 0.1 | GO:0005224 | ATP-binding and phosphorylation-dependent chloride channel activity(GO:0005224) channel-conductance-controlling ATPase activity(GO:0005260) |
| 0.0 | 0.0 | GO:0042056 | chemoattractant activity(GO:0042056) |
| 0.0 | 1.3 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.0 | 1.5 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.0 | 0.1 | GO:0003983 | UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748) |
| 0.0 | 0.7 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
| 0.0 | 0.3 | GO:0008107 | galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127) |
| 0.0 | 0.3 | GO:0004522 | ribonuclease A activity(GO:0004522) |
| 0.0 | 0.4 | GO:0035004 | phosphatidylinositol 3-kinase activity(GO:0035004) |
| 0.0 | 0.3 | GO:0010859 | calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859) |
| 0.0 | 0.2 | GO:0015252 | hydrogen ion channel activity(GO:0015252) |
| 0.0 | 0.9 | GO:0005095 | GTPase inhibitor activity(GO:0005095) |
| 0.0 | 0.5 | GO:0004745 | retinol dehydrogenase activity(GO:0004745) |
| 0.0 | 0.2 | GO:0004321 | fatty-acyl-CoA synthase activity(GO:0004321) |
| 0.0 | 0.5 | GO:0004526 | ribonuclease P activity(GO:0004526) |
| 0.0 | 0.2 | GO:0016909 | JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909) |
| 0.0 | 0.4 | GO:0051637 | obsolete Gram-positive bacterial cell surface binding(GO:0051637) |
| 0.0 | 7.1 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.0 | 0.3 | GO:0031419 | cobalamin binding(GO:0031419) |
| 0.0 | 0.3 | GO:0015288 | porin activity(GO:0015288) |
| 0.0 | 0.1 | GO:0004797 | thymidine kinase activity(GO:0004797) |
| 0.0 | 0.3 | GO:0016670 | oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670) |
| 0.0 | 0.2 | GO:0031013 | troponin I binding(GO:0031013) |
| 0.0 | 0.1 | GO:0016778 | diphosphotransferase activity(GO:0016778) |
| 0.0 | 3.1 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.0 | 1.1 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 0.0 | 0.2 | GO:0031435 | mitogen-activated protein kinase kinase kinase binding(GO:0031435) |
| 0.0 | 0.1 | GO:0045499 | chemorepellent activity(GO:0045499) |
| 0.0 | 0.3 | GO:0015280 | ligand-gated sodium channel activity(GO:0015280) |
| 0.0 | 0.4 | GO:0016846 | carbon-sulfur lyase activity(GO:0016846) |
| 0.0 | 0.7 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.0 | 0.8 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.0 | 0.1 | GO:0002046 | opsin binding(GO:0002046) |
| 0.0 | 0.1 | GO:0018685 | alkane 1-monooxygenase activity(GO:0018685) |
| 0.0 | 0.1 | GO:0004346 | glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309) |
| 0.0 | 6.4 | GO:0008022 | protein C-terminus binding(GO:0008022) |
| 0.0 | 0.7 | GO:0005242 | inward rectifier potassium channel activity(GO:0005242) |
| 0.0 | 0.2 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
| 0.0 | 1.0 | GO:0004869 | cysteine-type endopeptidase inhibitor activity(GO:0004869) |
| 0.0 | 0.1 | GO:0004663 | Rab geranylgeranyltransferase activity(GO:0004663) |
| 0.0 | 0.3 | GO:0003711 | obsolete transcription elongation regulator activity(GO:0003711) |
| 0.0 | 0.2 | GO:0015643 | toxic substance binding(GO:0015643) |
| 0.0 | 0.2 | GO:0004703 | G-protein coupled receptor kinase activity(GO:0004703) |
| 0.0 | 0.2 | GO:0015321 | sodium-dependent phosphate transmembrane transporter activity(GO:0015321) |
| 0.0 | 0.1 | GO:0017096 | acetylserotonin O-methyltransferase activity(GO:0017096) |
| 0.0 | 0.1 | GO:0046975 | histone methyltransferase activity (H3-K36 specific)(GO:0046975) |
| 0.0 | 0.2 | GO:0008454 | alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454) |
| 0.0 | 0.3 | GO:0030544 | Hsp70 protein binding(GO:0030544) |
| 0.0 | 0.2 | GO:0004568 | chitinase activity(GO:0004568) |
| 0.0 | 0.2 | GO:0005522 | profilin binding(GO:0005522) |
| 0.0 | 0.4 | GO:0050786 | RAGE receptor binding(GO:0050786) |
| 0.0 | 0.1 | GO:0050528 | acyloxyacyl hydrolase activity(GO:0050528) |
| 0.0 | 0.3 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 0.0 | 0.1 | GO:0032137 | guanine/thymine mispair binding(GO:0032137) |
| 0.0 | 0.1 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
| 0.0 | 0.3 | GO:0015101 | organic cation transmembrane transporter activity(GO:0015101) |
| 0.0 | 0.1 | GO:0051018 | protein kinase A binding(GO:0051018) |
| 0.0 | 0.2 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
| 0.0 | 0.1 | GO:0016929 | SUMO-specific protease activity(GO:0016929) |
| 0.0 | 0.2 | GO:0004859 | phospholipase inhibitor activity(GO:0004859) |
| 0.0 | 0.3 | GO:0008395 | steroid hydroxylase activity(GO:0008395) |
| 0.0 | 1.3 | GO:0051015 | actin filament binding(GO:0051015) |
| 0.0 | 0.2 | GO:0004117 | calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) |
| 0.0 | 0.3 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.0 | 0.2 | GO:0002162 | dystroglycan binding(GO:0002162) |
| 0.0 | 3.3 | GO:0000287 | magnesium ion binding(GO:0000287) |
| 0.0 | 0.7 | GO:0008601 | protein phosphatase type 2A regulator activity(GO:0008601) |
| 0.0 | 0.0 | GO:0003996 | acyl-CoA ligase activity(GO:0003996) |
| 0.0 | 0.3 | GO:0017166 | vinculin binding(GO:0017166) |
| 0.0 | 0.2 | GO:0036041 | long-chain fatty acid binding(GO:0036041) |
| 0.0 | 0.2 | GO:0015450 | P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450) |
| 0.0 | 0.7 | GO:0003684 | damaged DNA binding(GO:0003684) |
| 0.0 | 0.2 | GO:0016493 | C-C chemokine receptor activity(GO:0016493) |
| 0.0 | 9.8 | GO:0005509 | calcium ion binding(GO:0005509) |
| 0.0 | 0.1 | GO:0030547 | receptor inhibitor activity(GO:0030547) receptor antagonist activity(GO:0048019) |
| 0.0 | 0.1 | GO:0060590 | ATPase regulator activity(GO:0060590) |
| 0.0 | 0.1 | GO:0008131 | primary amine oxidase activity(GO:0008131) |
| 0.0 | 0.3 | GO:0004519 | endonuclease activity(GO:0004519) |
| 0.0 | 0.1 | GO:0008466 | glycogenin glucosyltransferase activity(GO:0008466) |
| 0.0 | 0.1 | GO:0003785 | actin monomer binding(GO:0003785) |
| 0.0 | 0.0 | GO:0031432 | titin binding(GO:0031432) |
| 0.0 | 0.6 | GO:0008009 | chemokine activity(GO:0008009) |
| 0.0 | 0.1 | GO:0008195 | phosphatidate phosphatase activity(GO:0008195) |
| 0.0 | 0.3 | GO:0005516 | calmodulin binding(GO:0005516) |
| 0.0 | 0.2 | GO:0008503 | benzodiazepine receptor activity(GO:0008503) |
| 0.0 | 0.2 | GO:0005044 | scavenger receptor activity(GO:0005044) |
| 0.0 | 0.3 | GO:0008378 | galactosyltransferase activity(GO:0008378) |
| 0.0 | 0.4 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
| 0.0 | 0.1 | GO:0042169 | SH2 domain binding(GO:0042169) |
| 0.0 | 0.4 | GO:0004536 | deoxyribonuclease activity(GO:0004536) |
| 0.0 | 0.5 | GO:0032947 | protein complex scaffold(GO:0032947) |
| 0.0 | 1.1 | GO:0017016 | Ras GTPase binding(GO:0017016) |
| 0.0 | 3.6 | GO:0030695 | GTPase regulator activity(GO:0030695) |
| 0.0 | 0.1 | GO:0052866 | phosphatidylinositol phosphate phosphatase activity(GO:0052866) |
| 0.0 | 0.2 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.0 | 0.0 | GO:0031702 | type 1 angiotensin receptor binding(GO:0031702) |
| 0.0 | 0.6 | GO:0008094 | DNA-dependent ATPase activity(GO:0008094) |
| 0.0 | 0.1 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 0.0 | 0.4 | GO:0005245 | voltage-gated calcium channel activity(GO:0005245) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.8 | ST_WNT_BETA_CATENIN_PATHWAY | Wnt/beta-catenin Pathway |
| 0.1 | 2.6 | SIG_IL4RECEPTOR_IN_B_LYPHOCYTES | Genes related to IL4 rceptor signaling in B lymphocytes |
| 0.0 | 0.2 | ST_IL_13_PATHWAY | Interleukin 13 (IL-13) Pathway |
| 0.0 | 0.4 | SA_CASPASE_CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
| 0.0 | 0.5 | ST_P38_MAPK_PATHWAY | p38 MAPK Pathway |
| 0.0 | 0.6 | ST_G_ALPHA_I_PATHWAY | G alpha i Pathway |
| 0.0 | 0.3 | ST_ADRENERGIC | Adrenergic Pathway |
| 0.0 | 0.4 | ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY | PI3K Pathway |
| 0.0 | 0.2 | ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS | Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway. |
|
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