Motif ID: MLXIPL

Z-value: 1.646


Transcription factors associated with MLXIPL:

Gene SymbolEntrez IDGene Name
MLXIPL ENSG00000009950.11 MLXIPL



Activity profile for motif MLXIPL.

activity profile for motif MLXIPL


Sorted Z-values histogram for motif MLXIPL

Sorted Z-values for motif MLXIPL



Network of associatons between targets according to the STRING database.



First level regulatory network of MLXIPL

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_+_226658 3.054 ENST00000320868.5
ENST00000397797.1
HBA1

hemoglobin, alpha 1

chr1_-_32801825 2.078 ENST00000329421.7
MARCKSL1
MARCKS-like 1
chr16_+_23847267 1.693 ENST00000321728.7
PRKCB
protein kinase C, beta
chr8_+_142402089 1.603 ENST00000521578.1
ENST00000520105.1
ENST00000523147.1
PTP4A3


protein tyrosine phosphatase type IVA, member 3


chr10_+_60145155 1.582 ENST00000373895.3
TFAM
transcription factor A, mitochondrial
chr10_+_60144782 1.493 ENST00000487519.1
TFAM
transcription factor A, mitochondrial
chr16_+_222846 1.403 ENST00000251595.6
ENST00000397806.1
HBA2

hemoglobin, alpha 2

chr17_-_62084241 1.396 ENST00000449662.2
ICAM2
intercellular adhesion molecule 2
chr19_-_39826639 1.282 ENST00000602185.1
ENST00000598034.1
ENST00000601387.1
ENST00000595636.1
ENST00000253054.8
ENST00000594700.1
ENST00000597595.1
GMFG






glia maturation factor, gamma






chrX_+_49188094 1.261 ENST00000381751.1
GAGE13
G antigen 13
chrX_+_49296814 1.214 ENST00000420398.2
GAGE12C
G antigen 12C
chr19_+_45418067 1.190 ENST00000589078.1
ENST00000586638.1
APOC1

apolipoprotein C-I

chrX_+_49363665 1.150 ENST00000381700.6
GAGE1
G antigen 1
chr22_-_22901636 1.144 ENST00000406503.1
ENST00000439106.1
ENST00000402697.1
ENST00000543184.1
ENST00000398743.2
PRAME




preferentially expressed antigen in melanoma




chr19_-_10450287 1.108 ENST00000589261.1
ENST00000590569.1
ENST00000589580.1
ENST00000589249.1
ICAM3



intercellular adhesion molecule 3



chrX_+_140991649 1.098 ENST00000285879.4
MAGEC1
melanoma antigen family C, 1
chr22_+_23040274 1.096 ENST00000390306.2
IGLV2-23
immunoglobulin lambda variable 2-23
chr19_+_45417812 1.013 ENST00000592535.1
APOC1
apolipoprotein C-I
chr15_-_58357932 1.010 ENST00000347587.3
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr21_-_44495919 1.001 ENST00000398158.1
CBS
cystathionine-beta-synthase
chrX_-_153881842 0.989 ENST00000369585.3
ENST00000247306.4
CTAG2

cancer/testis antigen 2

chr19_-_49956728 0.988 ENST00000601825.1
ENST00000596049.1
ENST00000599366.1
ENST00000597415.1
PIH1D1



PIH1 domain containing 1



chr16_-_89043377 0.983 ENST00000436887.2
ENST00000448839.1
ENST00000360302.2
CBFA2T3


core-binding factor, runt domain, alpha subunit 2; translocated to, 3


chr22_+_19467261 0.983 ENST00000455750.1
ENST00000437685.2
ENST00000263201.1
ENST00000404724.3
CDC45



cell division cycle 45



chr3_-_182833863 0.955 ENST00000492597.1
MCCC1
methylcrotonoyl-CoA carboxylase 1 (alpha)
chr19_+_45417921 0.925 ENST00000252491.4
ENST00000592885.1
ENST00000589781.1
APOC1


apolipoprotein C-I


chr17_-_62097904 0.922 ENST00000583366.1
ICAM2
intercellular adhesion molecule 2
chr19_+_10216899 0.922 ENST00000253107.7
ENST00000556468.1
ENST00000393793.1
ENST00000428358.1
ENST00000393796.4
PPAN


PPAN-P2RY11

peter pan homolog (Drosophila)


PPAN-P2RY11 readthrough

chrX_+_30233668 0.902 ENST00000378988.4
MAGEB2
melanoma antigen family B, 2
chr8_+_86089460 0.897 ENST00000418930.2
E2F5
E2F transcription factor 5, p130-binding
chrX_+_49178536 0.897 ENST00000442437.2
GAGE12J
G antigen 12J
chr14_-_106209368 0.886 ENST00000390548.2
ENST00000390549.2
ENST00000390542.2
IGHG1


immunoglobulin heavy constant gamma 1 (G1m marker)


chr14_-_106092403 0.886 ENST00000390543.2
IGHG4
immunoglobulin heavy constant gamma 4 (G4m marker)
chr8_-_124428569 0.881 ENST00000521903.1
ATAD2
ATPase family, AAA domain containing 2
chr20_+_61273797 0.879 ENST00000217159.1
SLCO4A1
solute carrier organic anion transporter family, member 4A1
chr7_+_50344289 0.857 ENST00000413698.1
ENST00000359197.5
ENST00000331340.3
ENST00000357364.4
ENST00000343574.5
ENST00000349824.4
ENST00000346667.4
ENST00000440768.2
IKZF1







IKAROS family zinc finger 1 (Ikaros)







chr17_+_76164639 0.853 ENST00000225777.3
ENST00000585591.1
ENST00000589711.1
ENST00000588282.1
ENST00000589168.1
SYNGR2




synaptogyrin 2




chrX_+_49216659 0.848 ENST00000415752.1
GAGE12I
G antigen 12I
chr17_-_62097927 0.843 ENST00000578313.1
ENST00000584084.1
ENST00000579788.1
ENST00000579687.1
ENST00000578379.1
ENST00000578892.1
ENST00000412356.1
ENST00000418105.1
ICAM2







intercellular adhesion molecule 2







chr15_-_41624685 0.840 ENST00000560640.1
ENST00000220514.3
OIP5

Opa interacting protein 5

chr1_-_202130702 0.825 ENST00000309017.3
ENST00000477554.1
ENST00000492451.1
PTPN7


protein tyrosine phosphatase, non-receptor type 7


chr1_-_92351769 0.823 ENST00000212355.4
TGFBR3
transforming growth factor, beta receptor III
chr20_+_60718785 0.808 ENST00000421564.1
ENST00000450482.1
ENST00000331758.3
SS18L1


synovial sarcoma translocation gene on chromosome 18-like 1


chr14_-_106174960 0.800 ENST00000390547.2
IGHA1
immunoglobulin heavy constant alpha 1
chr22_+_23243156 0.797 ENST00000390323.2
IGLC2
immunoglobulin lambda constant 2 (Kern-Oz- marker)
chr6_+_24775641 0.795 ENST00000378054.2
ENST00000476555.1
GMNN

geminin, DNA replication inhibitor

chr15_-_55611306 0.794 ENST00000563262.1
RAB27A
RAB27A, member RAS oncogene family
chrX_+_153813407 0.785 ENST00000443287.2
ENST00000333128.3
CTAG1A

cancer/testis antigen 1A

chr2_-_44223138 0.779 ENST00000260665.7
LRPPRC
leucine-rich pentatricopeptide repeat containing
chr12_-_9913489 0.778 ENST00000228434.3
ENST00000536709.1
CD69

CD69 molecule

chr1_+_179050512 0.778 ENST00000367627.3
TOR3A
torsin family 3, member A
chr22_+_23248512 0.770 ENST00000390325.2
IGLC3
immunoglobulin lambda constant 3 (Kern-Oz+ marker)
chr16_+_81040794 0.769 ENST00000439957.3
ENST00000393335.3
ENST00000428963.2
ENST00000564669.1
CENPN



centromere protein N



chrX_+_52238974 0.764 ENST00000375613.3
XAGE1B
X antigen family, member 1B
chr14_-_107219365 0.761 ENST00000424969.2
IGHV3-74
immunoglobulin heavy variable 3-74
chr1_+_65613217 0.760 ENST00000545314.1
AK4
adenylate kinase 4
chr16_-_88717482 0.759 ENST00000261623.3
CYBA
cytochrome b-245, alpha polypeptide
chr20_+_61287711 0.753 ENST00000370507.1
SLCO4A1
solute carrier organic anion transporter family, member 4A1
chr11_-_73689037 0.738 ENST00000544615.1
UCP2
uncoupling protein 2 (mitochondrial, proton carrier)
chr7_+_150065278 0.735 ENST00000519397.1
ENST00000479668.1
ENST00000540729.1
REPIN1


replication initiator 1


chr2_-_172290482 0.733 ENST00000442541.1
ENST00000392599.2
ENST00000375258.4
METTL8


methyltransferase like 8


chr2_+_47596287 0.731 ENST00000263735.4
EPCAM
epithelial cell adhesion molecule
chrX_+_192989 0.730 ENST00000399012.1
ENST00000430923.2
PLCXD1

phosphatidylinositol-specific phospholipase C, X domain containing 1

chr2_-_220083692 0.728 ENST00000265316.3
ABCB6
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr2_-_220083671 0.724 ENST00000439002.2
ABCB6
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr16_+_28943260 0.713 ENST00000538922.1
ENST00000324662.3
ENST00000567541.1
CD19


CD19 molecule


chr6_-_167370049 0.712 ENST00000366855.6
ENST00000508775.1
RNASET2

ribonuclease T2

chr17_+_79990058 0.709 ENST00000584341.1
RAC3
ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr10_-_70231639 0.709 ENST00000551118.2
ENST00000358410.3
ENST00000399180.2
ENST00000399179.2
DNA2



DNA replication helicase/nuclease 2



chr22_+_23264766 0.706 ENST00000390331.2
IGLC7
immunoglobulin lambda constant 7
chr12_-_8043736 0.703 ENST00000539924.1
SLC2A14
solute carrier family 2 (facilitated glucose transporter), member 14
chrX_+_37545012 0.702 ENST00000378616.3
XK
X-linked Kx blood group (McLeod syndrome)
chr2_+_6111712 0.683 ENST00000391666.2
FLJ30594
HCG1990367; Putative uncharacterized protein DKFZp761K2322; Putative uncharacterized protein FLJ30594; Uncharacterized protein; cDNA FLJ30594 fis, clone BRAWH2008903
chr7_+_23145366 0.682 ENST00000339077.5
ENST00000322275.5
ENST00000539124.1
ENST00000542558.1
KLHL7



kelch-like family member 7



chr14_-_106237742 0.672 ENST00000390551.2
IGHG3
immunoglobulin heavy constant gamma 3 (G3m marker)
chr1_-_212004090 0.667 ENST00000366997.4
LPGAT1
lysophosphatidylglycerol acyltransferase 1
chr3_-_53080047 0.667 ENST00000482396.1
ENST00000358080.2
ENST00000296295.6
ENST00000394752.3
SFMBT1



Scm-like with four mbt domains 1



chr1_+_65613340 0.656 ENST00000546702.1
AK4
adenylate kinase 4
chr12_+_93861264 0.652 ENST00000549982.1
ENST00000361630.2
MRPL42

mitochondrial ribosomal protein L42

chr2_+_216176540 0.650 ENST00000236959.9
ATIC
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr11_-_57177586 0.645 ENST00000529411.1
RP11-872D17.8
Uncharacterized protein
chr19_-_10450328 0.640 ENST00000160262.5
ICAM3
intercellular adhesion molecule 3
chr3_+_184081137 0.629 ENST00000443489.1
POLR2H
polymerase (RNA) II (DNA directed) polypeptide H
chr2_-_169769787 0.628 ENST00000451987.1
SPC25
SPC25, NDC80 kinetochore complex component
chrX_-_153847522 0.628 ENST00000328435.2
ENST00000359887.4
CTAG1B

cancer/testis antigen 1B

chr10_-_72142345 0.622 ENST00000373224.1
ENST00000446961.1
ENST00000358141.2
ENST00000357631.2
LRRC20



leucine rich repeat containing 20



chr17_+_16318850 0.615 ENST00000338560.7
TRPV2
transient receptor potential cation channel, subfamily V, member 2
chr19_-_23941680 0.613 ENST00000402377.3
ZNF681
zinc finger protein 681
chr4_-_103266355 0.611 ENST00000424970.2
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr11_+_59824060 0.611 ENST00000395032.2
ENST00000358152.2
MS4A3

membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)

chrX_-_11445856 0.610 ENST00000380736.1
ARHGAP6
Rho GTPase activating protein 6
chr20_+_31350184 0.610 ENST00000328111.2
ENST00000353855.2
ENST00000348286.2
DNMT3B


DNA (cytosine-5-)-methyltransferase 3 beta


chr5_-_137667459 0.607 ENST00000415130.2
ENST00000356505.3
ENST00000357274.3
ENST00000348983.3
ENST00000323760.6
CDC25C




cell division cycle 25C




chr16_+_15489603 0.605 ENST00000287594.7
ENST00000568766.1
MPV17L
RP11-1021N1.1
MPV17 mitochondrial membrane protein-like
Uncharacterized protein
chr17_+_34948228 0.604 ENST00000251312.5
ENST00000590554.1
DHRS11

dehydrogenase/reductase (SDR family) member 11

chr3_-_52804872 0.599 ENST00000535191.1
ENST00000461689.1
ENST00000383721.4
ENST00000233027.5
NEK4



NIMA-related kinase 4



chr14_-_23451467 0.599 ENST00000361265.4
ENST00000555074.1
AJUBA
RP11-298I3.5
ajuba LIM protein
RP11-298I3.5
chrX_-_52260355 0.598 ENST00000375602.1
ENST00000399800.3
XAGE1A

X antigen family, member 1A

chr17_+_79989937 0.598 ENST00000580965.1
RAC3
ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr19_+_50887585 0.597 ENST00000440232.2
ENST00000601098.1
ENST00000599857.1
ENST00000593887.1
POLD1



polymerase (DNA directed), delta 1, catalytic subunit



chr17_+_16318909 0.594 ENST00000577397.1
TRPV2
transient receptor potential cation channel, subfamily V, member 2
chr21_-_44495964 0.591 ENST00000398168.1
ENST00000398165.3
CBS

cystathionine-beta-synthase

chr1_-_182361327 0.591 ENST00000331872.6
ENST00000311223.5
GLUL

glutamate-ammonia ligase

chrX_-_71458802 0.590 ENST00000373657.1
ENST00000334463.3
ERCC6L

excision repair cross-complementing rodent repair deficiency, complementation group 6-like

chr11_+_59824127 0.588 ENST00000278865.3
MS4A3
membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chrX_+_102469997 0.581 ENST00000372695.5
ENST00000372691.3
BEX4

brain expressed, X-linked 4

chr2_-_170430277 0.581 ENST00000438035.1
ENST00000453929.2
FASTKD1

FAST kinase domains 1

chr2_-_73511559 0.580 ENST00000521871.1
FBXO41
F-box protein 41
chr4_-_103266626 0.578 ENST00000356736.4
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr6_+_31465892 0.576 ENST00000252229.6
ENST00000427115.1
MICB

MHC class I polypeptide-related sequence B

chr19_+_10217270 0.574 ENST00000446223.1
PPAN
peter pan homolog (Drosophila)
chr17_+_61678225 0.571 ENST00000258975.6
TACO1
translational activator of mitochondrially encoded cytochrome c oxidase I
chr19_-_39523165 0.569 ENST00000509137.2
ENST00000292853.4
FBXO27

F-box protein 27

chrX_-_3631635 0.565 ENST00000262848.5
PRKX
protein kinase, X-linked
chr14_-_106054659 0.563 ENST00000390539.2
IGHA2
immunoglobulin heavy constant alpha 2 (A2m marker)
chr19_-_59010565 0.561 ENST00000594786.1
SLC27A5
solute carrier family 27 (fatty acid transporter), member 5
chr11_+_65029421 0.556 ENST00000541089.1
POLA2
polymerase (DNA directed), alpha 2, accessory subunit
chr7_+_23145347 0.555 ENST00000322231.7
KLHL7
kelch-like family member 7
chr3_-_138553779 0.555 ENST00000461451.1
PIK3CB
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
chr6_+_24775153 0.552 ENST00000356509.3
ENST00000230056.3
GMNN

geminin, DNA replication inhibitor

chr2_-_21266935 0.549 ENST00000233242.1
APOB
apolipoprotein B
chr1_-_46152174 0.544 ENST00000290795.3
ENST00000355105.3
GPBP1L1

GC-rich promoter binding protein 1-like 1

chr12_-_63328817 0.542 ENST00000228705.6
PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr4_+_142142035 0.542 ENST00000262990.4
ENST00000512809.1
ENST00000503649.1
ENST00000512738.1
ENST00000421169.2
ZNF330




zinc finger protein 330




chr5_-_71616043 0.541 ENST00000508863.2
ENST00000522095.1
ENST00000513900.1
ENST00000515404.1
ENST00000457646.4
ENST00000261413.5
MRPS27





mitochondrial ribosomal protein S27





chr22_+_42949925 0.537 ENST00000327678.5
ENST00000340239.4
ENST00000407614.4
ENST00000335879.5
SERHL2



serine hydrolase-like 2



chr8_+_110552337 0.535 ENST00000337573.5
EBAG9
estrogen receptor binding site associated, antigen, 9
chr1_-_762885 0.533 ENST00000536430.1
ENST00000473798.1
LINC00115

long intergenic non-protein coding RNA 115

chr1_-_39407450 0.532 ENST00000372990.1
RHBDL2
rhomboid, veinlet-like 2 (Drosophila)
chr11_-_118213455 0.532 ENST00000300692.4
CD3D
CD3d molecule, delta (CD3-TCR complex)
chr1_+_65775204 0.531 ENST00000371069.4
DNAJC6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr10_-_69597915 0.529 ENST00000225171.2
DNAJC12
DnaJ (Hsp40) homolog, subfamily C, member 12
chr15_+_41057818 0.529 ENST00000558467.1
GCHFR
GTP cyclohydrolase I feedback regulator
chr12_+_6602517 0.526 ENST00000315579.5
ENST00000539714.1
NCAPD2

non-SMC condensin I complex, subunit D2

chr5_+_126112794 0.525 ENST00000261366.5
ENST00000395354.1
LMNB1

lamin B1

chr5_+_134240588 0.525 ENST00000254908.6
PCBD2
pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2
chr1_-_68516393 0.525 ENST00000395201.1
DIRAS3
DIRAS family, GTP-binding RAS-like 3
chr7_+_56119323 0.525 ENST00000275603.4
ENST00000335503.3
ENST00000540286.1
CCT6A


chaperonin containing TCP1, subunit 6A (zeta 1)


chr1_-_155270770 0.523 ENST00000392414.3
PKLR
pyruvate kinase, liver and RBC
chr5_-_137674000 0.523 ENST00000510119.1
ENST00000513970.1
CDC25C

cell division cycle 25C

chr1_+_111682058 0.523 ENST00000545121.1
CEPT1
choline/ethanolamine phosphotransferase 1
chr5_+_68665608 0.522 ENST00000509734.1
ENST00000354868.5
ENST00000521422.1
ENST00000354312.3
ENST00000345306.6
RAD17




RAD17 homolog (S. pombe)




chr19_+_10217364 0.519 ENST00000430370.1
PPAN
peter pan homolog (Drosophila)
chr14_-_21566731 0.519 ENST00000360947.3
ZNF219
zinc finger protein 219
chr1_+_45965725 0.516 ENST00000401061.4
MMACHC
methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
chr1_-_155271213 0.513 ENST00000342741.4
PKLR
pyruvate kinase, liver and RBC
chr8_-_101571933 0.508 ENST00000520311.1
ANKRD46
ankyrin repeat domain 46
chr2_-_128615681 0.508 ENST00000409955.1
ENST00000272645.4
POLR2D

polymerase (RNA) II (DNA directed) polypeptide D

chr7_+_1022811 0.506 ENST00000308919.7
CYP2W1
cytochrome P450, family 2, subfamily W, polypeptide 1
chr1_-_92371839 0.505 ENST00000370399.2
TGFBR3
transforming growth factor, beta receptor III
chr19_+_1067492 0.505 ENST00000586866.1
HMHA1
histocompatibility (minor) HA-1
chr7_+_23221613 0.504 ENST00000410002.3
ENST00000413919.1
NUPL2

nucleoporin like 2

chr19_+_926000 0.503 ENST00000263620.3
ARID3A
AT rich interactive domain 3A (BRIGHT-like)
chr19_-_10445399 0.501 ENST00000592945.1
ICAM3
intercellular adhesion molecule 3
chr18_+_657578 0.501 ENST00000323274.10
TYMS
thymidylate synthetase
chr2_+_127413704 0.501 ENST00000409836.3
GYPC
glycophorin C (Gerbich blood group)
chr22_+_23134974 0.500 ENST00000390314.2
IGLV2-11
immunoglobulin lambda variable 2-11
chr19_+_1067144 0.499 ENST00000313093.2
HMHA1
histocompatibility (minor) HA-1
chr1_+_114471972 0.499 ENST00000369559.4
ENST00000369554.2
HIPK1

homeodomain interacting protein kinase 1

chr12_-_104531785 0.496 ENST00000551727.1
NFYB
nuclear transcription factor Y, beta
chr2_+_10262442 0.496 ENST00000360566.2
RRM2
ribonucleotide reductase M2
chr7_+_74188309 0.496 ENST00000289473.4
ENST00000433458.1
NCF1

neutrophil cytosolic factor 1

chr1_+_114447763 0.495 ENST00000369563.3
DCLRE1B
DNA cross-link repair 1B
chr15_+_85525205 0.492 ENST00000394553.1
ENST00000339708.5
PDE8A

phosphodiesterase 8A

chr19_+_42381337 0.492 ENST00000597454.1
ENST00000444740.2
CD79A

CD79a molecule, immunoglobulin-associated alpha

chr8_-_131028660 0.491 ENST00000401979.2
ENST00000517654.1
ENST00000522361.1
ENST00000518167.1
FAM49B



family with sequence similarity 49, member B



chr15_-_68497657 0.490 ENST00000448060.2
ENST00000467889.1
CALML4

calmodulin-like 4

chr1_-_226595741 0.490 ENST00000366794.5
ENST00000366792.1
ENST00000366791.5
PARP1


poly (ADP-ribose) polymerase 1


chr5_-_68665296 0.488 ENST00000512152.1
ENST00000503245.1
ENST00000512561.1
ENST00000380822.4
TAF9



TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa



chr11_+_46402583 0.486 ENST00000359803.3
MDK
midkine (neurite growth-promoting factor 2)
chr15_-_58357866 0.485 ENST00000537372.1
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr11_-_61129335 0.484 ENST00000545361.1
ENST00000539128.1
ENST00000546151.1
ENST00000447532.2
CYB561A3



cytochrome b561 family, member A3



chr6_+_31465849 0.483 ENST00000399150.3
MICB
MHC class I polypeptide-related sequence B
chr7_+_112063192 0.483 ENST00000005558.4
IFRD1
interferon-related developmental regulator 1
chr1_-_15850676 0.482 ENST00000440484.1
ENST00000333868.5
CASP9

caspase 9, apoptosis-related cysteine peptidase

chr1_-_52870104 0.481 ENST00000371568.3
ORC1
origin recognition complex, subunit 1
chr6_+_33043703 0.479 ENST00000418931.2
ENST00000535465.1
HLA-DPB1

major histocompatibility complex, class II, DP beta 1

chr7_+_23221438 0.477 ENST00000258742.5
NUPL2
nucleoporin like 2
chr8_+_11351876 0.476 ENST00000529894.1
BLK
B lymphoid tyrosine kinase
chr7_-_149470297 0.473 ENST00000484747.1
ZNF467
zinc finger protein 467
chr8_+_110552831 0.472 ENST00000530629.1
EBAG9
estrogen receptor binding site associated, antigen, 9
chr8_-_145641864 0.472 ENST00000276833.5
SLC39A4
solute carrier family 39 (zinc transporter), member 4
chr11_-_32452357 0.471 ENST00000379079.2
ENST00000530998.1
WT1

Wilms tumor 1

chr16_-_88717423 0.471 ENST00000568278.1
ENST00000569359.1
ENST00000567174.1
CYBA


cytochrome b-245, alpha polypeptide


chr11_-_62439012 0.469 ENST00000532208.1
ENST00000377954.2
ENST00000415855.2
ENST00000431002.2
ENST00000354588.3
C11orf48




chromosome 11 open reading frame 48




chr1_-_63988846 0.468 ENST00000283568.8
ENST00000371092.3
ENST00000271002.10
ITGB3BP


integrin beta 3 binding protein (beta3-endonexin)


chr22_+_25960786 0.465 ENST00000324198.6
ADRBK2
adrenergic, beta, receptor kinase 2
chr1_-_111743285 0.465 ENST00000357640.4
DENND2D
DENN/MADD domain containing 2D
chr4_-_140098339 0.461 ENST00000394235.2
ELF2
E74-like factor 2 (ets domain transcription factor)
chr19_-_13044494 0.461 ENST00000593021.1
ENST00000587981.1
ENST00000423140.2
ENST00000314606.4
FARSA



phenylalanyl-tRNA synthetase, alpha subunit



chr9_-_136283075 0.458 ENST00000371935.2
ENST00000454825.1
REXO4

REX4, RNA exonuclease 4 homolog (S. cerevisiae)

chrX_-_70329118 0.455 ENST00000374188.3
IL2RG
interleukin 2 receptor, gamma
chr11_+_118955583 0.451 ENST00000278715.3
ENST00000536813.1
ENST00000537841.1
ENST00000542729.1
ENST00000546302.1
ENST00000442944.2
ENST00000544387.1
ENST00000543090.1
HMBS







hydroxymethylbilane synthase







chr1_-_145076186 0.450 ENST00000369348.3
PDE4DIP
phosphodiesterase 4D interacting protein
chr1_+_111682827 0.449 ENST00000357172.4
CEPT1
choline/ethanolamine phosphotransferase 1
chr11_+_64863587 0.448 ENST00000530773.1
ENST00000279281.3
ENST00000529180.1
VPS51


vacuolar protein sorting 51 homolog (S. cerevisiae)


chr2_-_37458749 0.447 ENST00000234170.5
CEBPZ
CCAAT/enhancer binding protein (C/EBP), zeta
chr2_+_47630108 0.446 ENST00000233146.2
ENST00000454849.1
ENST00000543555.1
MSH2


mutS homolog 2


chr16_-_81040719 0.445 ENST00000219400.3
CMC2
C-x(9)-C motif containing 2
chr10_+_112327425 0.445 ENST00000361804.4
SMC3
structural maintenance of chromosomes 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.1 GO:0010900 regulation of phosphatidylcholine catabolic process(GO:0010899) negative regulation of phosphatidylcholine catabolic process(GO:0010900)
0.8 3.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.6 1.9 GO:1990170 detoxification of cadmium ion(GO:0071585) stress response to cadmium ion(GO:1990170)
0.6 1.7 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.5 1.6 GO:0043418 cysteine biosynthetic process from serine(GO:0006535) homoserine metabolic process(GO:0009092) cysteine biosynthetic process via cystathionine(GO:0019343) transsulfuration(GO:0019346) homocysteine catabolic process(GO:0043418)
0.4 1.3 GO:0060318 definitive erythrocyte differentiation(GO:0060318)
0.4 1.3 GO:0006273 lagging strand elongation(GO:0006273)
0.3 1.1 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.3 0.3 GO:0042359 vitamin D metabolic process(GO:0042359)
0.3 1.3 GO:0003093 regulation of glomerular filtration(GO:0003093) glomerular filtration(GO:0003094) renal filtration(GO:0097205) regulation of renal system process(GO:0098801)
0.3 0.8 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.2 1.0 GO:0000491 small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.2 1.0 GO:0006768 biotin metabolic process(GO:0006768)
0.2 0.9 GO:0040016 embryonic cleavage(GO:0040016)
0.2 1.1 GO:0009439 cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440)
0.2 0.7 GO:0007518 myoblast fate determination(GO:0007518)
0.2 1.6 GO:1901698 response to nitrogen compound(GO:1901698)
0.2 0.8 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.2 1.6 GO:0006188 IMP biosynthetic process(GO:0006188) IMP metabolic process(GO:0046040)
0.2 1.4 GO:0015671 oxygen transport(GO:0015671)
0.2 0.8 GO:0009186 deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.2 1.0 GO:0051570 regulation of histone H3-K9 methylation(GO:0051570)
0.2 1.6 GO:0070327 thyroid hormone transport(GO:0070327)
0.2 0.5 GO:0043095 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.2 0.5 GO:0046521 sphingoid catabolic process(GO:0046521)
0.2 0.5 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.2 0.7 GO:0010520 regulation of reciprocal meiotic recombination(GO:0010520) negative regulation of meiotic nuclear division(GO:0045835) regulation of meiosis I(GO:0060631)
0.2 0.5 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162) pyrimidine deoxyribonucleoside monophosphate metabolic process(GO:0009176) pyrimidine deoxyribonucleotide biosynthetic process(GO:0009221) transformation of host cell by virus(GO:0019087) dUMP metabolic process(GO:0046078) intestinal epithelial cell maturation(GO:0060574) intestinal epithelial cell development(GO:0060576)
0.2 1.5 GO:1900087 traversing start control point of mitotic cell cycle(GO:0007089) positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) positive regulation of cell cycle G1/S phase transition(GO:1902808)
0.2 0.5 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.2 0.8 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.2 0.5 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.2 1.1 GO:0050689 negative regulation of defense response to virus by host(GO:0050689)
0.2 0.5 GO:0097237 response to cobalt ion(GO:0032025) cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.1 0.6 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 1.3 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 0.7 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
0.1 0.5 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.1 1.4 GO:0000076 DNA replication checkpoint(GO:0000076)
0.1 0.1 GO:0001836 release of cytochrome c from mitochondria(GO:0001836)
0.1 0.8 GO:0042098 T cell proliferation(GO:0042098)
0.1 0.7 GO:0032933 SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.1 0.4 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.1 0.8 GO:0043316 natural killer cell activation involved in immune response(GO:0002323) cytotoxic T cell degranulation(GO:0043316) natural killer cell degranulation(GO:0043320)
0.1 0.4 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.1 0.5 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.1 0.4 GO:0019827 stem cell population maintenance(GO:0019827) maintenance of cell number(GO:0098727)
0.1 0.5 GO:0061032 visceral serous pericardium development(GO:0061032)
0.1 0.3 GO:0014900 smooth muscle hyperplasia(GO:0014806) muscle hyperplasia(GO:0014900) positive regulation of guanylate cyclase activity(GO:0031284)
0.1 2.8 GO:0031055 DNA replication-independent nucleosome assembly(GO:0006336) chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) DNA replication-independent nucleosome organization(GO:0034724) CENP-A containing chromatin organization(GO:0061641)
0.1 0.3 GO:0071848 regulation of fever generation by regulation of prostaglandin secretion(GO:0071810) positive regulation of fever generation by positive regulation of prostaglandin secretion(GO:0071812) TNFSF11-mediated signaling pathway(GO:0071847) positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling(GO:0071848) regulation of fever generation by prostaglandin secretion(GO:0100009)
0.1 0.3 GO:0051661 maintenance of centrosome location(GO:0051661)
0.1 0.4 GO:0042816 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.1 0.3 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.1 0.7 GO:0030952 establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.1 0.3 GO:0000338 protein deneddylation(GO:0000338)
0.1 0.3 GO:0009174 UMP biosynthetic process(GO:0006222) pyrimidine nucleoside monophosphate metabolic process(GO:0009129) pyrimidine nucleoside monophosphate biosynthetic process(GO:0009130) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.1 0.3 GO:0018283 metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283)
0.1 0.6 GO:0034501 protein localization to kinetochore(GO:0034501)
0.1 0.4 GO:0051958 methotrexate transport(GO:0051958)
0.1 0.1 GO:0070922 small RNA loading onto RISC(GO:0070922)
0.1 0.3 GO:0046618 drug export(GO:0046618)
0.1 0.6 GO:0043247 protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.1 1.0 GO:0006776 vitamin A metabolic process(GO:0006776)
0.1 0.6 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.1 0.4 GO:0034086 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.1 0.2 GO:0002678 positive regulation of chronic inflammatory response(GO:0002678)
0.1 0.1 GO:0032736 positive regulation of interleukin-13 production(GO:0032736)
0.1 0.3 GO:0090467 L-arginine import(GO:0043091) arginine import(GO:0090467) L-arginine transport(GO:1902023)
0.1 0.1 GO:0060535 trachea cartilage morphogenesis(GO:0060535) cartilage morphogenesis(GO:0060536)
0.1 2.1 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.1 0.2 GO:0050709 negative regulation of protein secretion(GO:0050709)
0.1 2.6 GO:0006270 DNA replication initiation(GO:0006270)
0.1 0.2 GO:0006530 asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.1 0.3 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.1 0.5 GO:0045059 positive thymic T cell selection(GO:0045059)
0.1 0.3 GO:0015917 aminophospholipid transport(GO:0015917)
0.1 0.5 GO:0015755 fructose transport(GO:0015755)
0.1 0.5 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729)
0.1 0.7 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.1 0.4 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.1 0.2 GO:0046473 phosphatidic acid metabolic process(GO:0046473)
0.1 0.5 GO:0033160 positive regulation of protein import into nucleus, translocation(GO:0033160)
0.1 0.3 GO:0060457 negative regulation of digestive system process(GO:0060457)
0.1 1.2 GO:0060760 positive regulation of response to cytokine stimulus(GO:0060760)
0.1 0.2 GO:0090009 primitive streak formation(GO:0090009)
0.1 1.2 GO:0006386 transcription elongation from RNA polymerase III promoter(GO:0006385) termination of RNA polymerase III transcription(GO:0006386)
0.1 0.3 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.1 0.7 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.1 0.5 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.1 0.2 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.1 0.8 GO:0034643 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.1 0.3 GO:0014053 negative regulation of gamma-aminobutyric acid secretion(GO:0014053)
0.1 0.2 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248) post-embryonic camera-type eye development(GO:0031077) post-embryonic organ morphogenesis(GO:0048563)
0.1 0.5 GO:0007090 obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.1 0.5 GO:0050849 negative regulation of calcium-mediated signaling(GO:0050849)
0.1 0.3 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 0.4 GO:0032495 response to muramyl dipeptide(GO:0032495)
0.1 0.1 GO:0006505 GPI anchor metabolic process(GO:0006505)
0.1 0.2 GO:0051311 meiotic metaphase I plate congression(GO:0043060) spindle midzone assembly(GO:0051255) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311)
0.1 0.4 GO:0051290 protein heterotetramerization(GO:0051290)
0.1 0.7 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.1 0.4 GO:0045579 positive regulation of B cell differentiation(GO:0045579)
0.1 0.2 GO:0006679 glucosylceramide biosynthetic process(GO:0006679)
0.1 0.2 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.1 0.1 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586) positive regulation of gamma-delta T cell differentiation(GO:0045588) regulation of gamma-delta T cell activation(GO:0046643) positive regulation of gamma-delta T cell activation(GO:0046645)
0.1 0.4 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.1 0.5 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.1 0.3 GO:0015886 heme transport(GO:0015886)
0.1 0.4 GO:0016075 rRNA catabolic process(GO:0016075)
0.1 1.4 GO:0051225 spindle assembly(GO:0051225)
0.1 0.4 GO:0006855 drug transmembrane transport(GO:0006855)
0.1 0.2 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1 0.2 GO:0000012 single strand break repair(GO:0000012)
0.1 0.3 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.1 0.2 GO:0008637 apoptotic mitochondrial changes(GO:0008637)
0.1 0.2 GO:0019370 leukotriene biosynthetic process(GO:0019370)
0.1 0.3 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.1 0.2 GO:0042159 lipoprotein catabolic process(GO:0042159)
0.1 0.3 GO:0009143 nucleoside triphosphate catabolic process(GO:0009143)
0.1 0.2 GO:0090224 regulation of mitotic spindle organization(GO:0060236) regulation of spindle organization(GO:0090224)
0.1 0.2 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) glycosylceramide biosynthetic process(GO:0046476)
0.1 0.2 GO:0061298 retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1 0.2 GO:0000354 cis assembly of pre-catalytic spliceosome(GO:0000354)
0.1 0.2 GO:0009106 lipoate metabolic process(GO:0009106)
0.1 1.2 GO:0000303 response to superoxide(GO:0000303)
0.1 0.2 GO:0006166 purine ribonucleoside salvage(GO:0006166)
0.1 0.3 GO:0006448 regulation of translational elongation(GO:0006448)
0.1 0.1 GO:0060398 regulation of growth hormone receptor signaling pathway(GO:0060398)
0.1 0.2 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.1 0.2 GO:1904037 positive regulation of epithelial cell apoptotic process(GO:1904037) positive regulation of endothelial cell apoptotic process(GO:2000353)
0.1 0.3 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.1 0.7 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.1 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
0.0 1.2 GO:0007052 mitotic spindle organization(GO:0007052)
0.0 1.6 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 0.1 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.4 GO:0051325 interphase(GO:0051325)
0.0 0.3 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.3 GO:0035246 peptidyl-arginine N-methylation(GO:0035246)
0.0 0.2 GO:0045767 obsolete regulation of anti-apoptosis(GO:0045767)
0.0 0.2 GO:0042574 retinal metabolic process(GO:0042574)
0.0 0.5 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.1 GO:0014889 muscle atrophy(GO:0014889)
0.0 0.2 GO:0000959 mitochondrial RNA metabolic process(GO:0000959) transcription from mitochondrial promoter(GO:0006390)
0.0 0.2 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.3 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.1 GO:0015904 tetracycline transport(GO:0015904)
0.0 0.2 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.0 0.1 GO:0035608 protein deglutamylation(GO:0035608)
0.0 0.3 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.2 GO:0051852 disruption by host of symbiont cells(GO:0051852) killing by host of symbiont cells(GO:0051873)
0.0 0.0 GO:0000768 syncytium formation by plasma membrane fusion(GO:0000768) syncytium formation(GO:0006949)
0.0 0.2 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.3 GO:0001782 B cell homeostasis(GO:0001782)
0.0 0.2 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0 0.6 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.2 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894) contact inhibition(GO:0060242) positive regulation of cell junction assembly(GO:1901890) positive regulation of adherens junction organization(GO:1903393)
0.0 0.3 GO:0009120 deoxyribonucleoside metabolic process(GO:0009120)
0.0 0.1 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0 2.6 GO:0008033 tRNA processing(GO:0008033)
0.0 0.2 GO:0001508 action potential(GO:0001508)
0.0 0.1 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.0 0.3 GO:0042738 exogenous drug catabolic process(GO:0042738)
0.0 0.1 GO:0032776 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0 0.4 GO:0060046 regulation of acrosome reaction(GO:0060046)
0.0 0.3 GO:0014741 negative regulation of cardiac muscle hypertrophy(GO:0010614) negative regulation of muscle hypertrophy(GO:0014741)
0.0 0.1 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.3 GO:0009057 macromolecule catabolic process(GO:0009057)
0.0 0.1 GO:0045091 regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.0 0.1 GO:0032070 regulation of deoxyribonuclease activity(GO:0032070)
0.0 0.3 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
0.0 0.2 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.1 GO:0046368 GDP-L-fucose biosynthetic process(GO:0042350) 'de novo' GDP-L-fucose biosynthetic process(GO:0042351) GDP-L-fucose metabolic process(GO:0046368)
0.0 0.8 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 0.6 GO:0045730 respiratory burst(GO:0045730)
0.0 1.2 GO:0030325 adrenal gland development(GO:0030325)
0.0 0.3 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005) negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0 0.1 GO:0032328 alanine transport(GO:0032328)
0.0 0.4 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.0 0.1 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.5 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.1 GO:0035470 positive regulation of vascular wound healing(GO:0035470)
0.0 0.1 GO:0048075 positive regulation of eye pigmentation(GO:0048075)
0.0 1.1 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.0 0.3 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.4 GO:0071333 cellular response to monosaccharide stimulus(GO:0071326) cellular response to hexose stimulus(GO:0071331) cellular response to glucose stimulus(GO:0071333)
0.0 0.1 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.0 0.4 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.0 0.1 GO:0071883 adrenergic receptor signaling pathway(GO:0071875) activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0 0.3 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 1.0 GO:0030851 granulocyte differentiation(GO:0030851)
0.0 0.3 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.2 GO:0014002 astrocyte development(GO:0014002)
0.0 0.1 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055) negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0 0.1 GO:0033033 negative regulation of myeloid cell apoptotic process(GO:0033033)
0.0 0.5 GO:0006349 regulation of gene expression by genetic imprinting(GO:0006349)
0.0 0.2 GO:0030828 positive regulation of cGMP biosynthetic process(GO:0030828)
0.0 1.2 GO:0060338 regulation of type I interferon-mediated signaling pathway(GO:0060338)
0.0 0.3 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.0 0.3 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.1 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.0 0.3 GO:0046653 tetrahydrofolate metabolic process(GO:0046653)
0.0 0.1 GO:0002384 hepatic immune response(GO:0002384)
0.0 0.2 GO:0045003 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 0.2 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.1 GO:0050858 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.2 GO:0060999 positive regulation of dendritic spine development(GO:0060999) positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 1.3 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.0 0.2 GO:0032527 retrograde protein transport, ER to cytosol(GO:0030970) protein exit from endoplasmic reticulum(GO:0032527)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.1 GO:0070781 response to biotin(GO:0070781)
0.0 0.2 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.4 GO:0060041 retina development in camera-type eye(GO:0060041)
0.0 0.1 GO:0046855 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.0 0.1 GO:0003057 regulation of the force of heart contraction by chemical signal(GO:0003057)
0.0 0.1 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0 0.1 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.0 0.1 GO:1902170 cellular response to nitric oxide(GO:0071732) cellular response to reactive nitrogen species(GO:1902170)
0.0 0.1 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.1 GO:0008089 anterograde axonal transport(GO:0008089)
0.0 0.1 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.1 GO:0061364 luteolysis(GO:0001554) response to cortisol(GO:0051414) apoptotic process involved in luteolysis(GO:0061364)
0.0 0.1 GO:0019056 modulation by virus of host transcription(GO:0019056) regulation of sprouting of injured axon(GO:0048686) positive regulation of sprouting of injured axon(GO:0048687) regulation of axon extension involved in regeneration(GO:0048690) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.0 0.3 GO:0015695 organic cation transport(GO:0015695)
0.0 0.1 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.1 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.0 1.2 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.0 0.1 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.0 0.2 GO:0043525 positive regulation of neuron apoptotic process(GO:0043525) positive regulation of neuron death(GO:1901216)
0.0 0.1 GO:0010536 regulation of activation of Janus kinase activity(GO:0010533) positive regulation of activation of Janus kinase activity(GO:0010536)
0.0 0.1 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.3 GO:0035036 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036)
0.0 0.3 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi vesicle budding(GO:0048194) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.4 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.2 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.0 0.3 GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.0 0.2 GO:0032613 interleukin-10 production(GO:0032613)
0.0 0.2 GO:0006600 creatine metabolic process(GO:0006600)
0.0 1.0 GO:0006626 protein targeting to mitochondrion(GO:0006626)
0.0 0.2 GO:0033523 histone H2B ubiquitination(GO:0033523)
0.0 0.2 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.0 GO:0033260 nuclear DNA replication(GO:0033260)
0.0 0.4 GO:0002639 positive regulation of immunoglobulin production(GO:0002639)
0.0 1.1 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.0 0.2 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.3 GO:0006974 cellular response to DNA damage stimulus(GO:0006974)
0.0 0.4 GO:0000060 protein import into nucleus, translocation(GO:0000060)
0.0 0.1 GO:0090267 positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.3 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.3 GO:0009713 catechol-containing compound biosynthetic process(GO:0009713) catecholamine biosynthetic process(GO:0042423)
0.0 0.2 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.3 GO:0030317 sperm motility(GO:0030317)
0.0 0.3 GO:1902591 vesicle coating(GO:0006901) single-organism membrane budding(GO:1902591)
0.0 0.1 GO:0032916 transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910) positive regulation of transforming growth factor beta3 production(GO:0032916)
0.0 0.2 GO:0032651 regulation of interleukin-1 beta production(GO:0032651)
0.0 0.1 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.2 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.1 GO:0030261 chromosome condensation(GO:0030261)
0.0 0.3 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.2 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.3 GO:0046006 positive regulation of activated T cell proliferation(GO:0042104) regulation of activated T cell proliferation(GO:0046006)
0.0 0.2 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.0 0.2 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.0 0.1 GO:0046514 ceramide catabolic process(GO:0046514)
0.0 0.2 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0 0.1 GO:0015811 sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.0 0.1 GO:0046208 spermine catabolic process(GO:0046208)
0.0 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.4 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.0 3.1 GO:0051028 mRNA transport(GO:0051028)
0.0 0.0 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.0 0.2 GO:0019221 cytokine-mediated signaling pathway(GO:0019221)
0.0 0.2 GO:0051319 mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.0 GO:0003077 obsolete negative regulation of diuresis(GO:0003077)
0.0 0.2 GO:0045350 interferon-beta biosynthetic process(GO:0045350) regulation of interferon-beta biosynthetic process(GO:0045357) positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.0 0.1 GO:0060068 vagina development(GO:0060068)
0.0 0.1 GO:0042637 catagen(GO:0042637)
0.0 0.3 GO:0006221 pyrimidine nucleotide biosynthetic process(GO:0006221)
0.0 0.2 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.1 GO:0048659 smooth muscle cell proliferation(GO:0048659)
0.0 0.1 GO:0003160 endocardium development(GO:0003157) endocardium morphogenesis(GO:0003160) endocardium formation(GO:0060214)
0.0 0.2 GO:0046320 regulation of fatty acid oxidation(GO:0046320)
0.0 0.1 GO:0045953 negative regulation of natural killer cell mediated immunity(GO:0002716) negative regulation of natural killer cell mediated cytotoxicity(GO:0045953)
0.0 0.1 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.5 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 0.1 GO:0051013 microtubule severing(GO:0051013)
0.0 0.1 GO:0042255 ribosome assembly(GO:0042255)
0.0 0.2 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 1.0 GO:0000236 mitotic prometaphase(GO:0000236)
0.0 0.8 GO:0051084 'de novo' posttranslational protein folding(GO:0051084)
0.0 0.0 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.1 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 0.1 GO:0009128 AMP catabolic process(GO:0006196) nucleoside monophosphate catabolic process(GO:0009125) purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0 0.2 GO:0009086 methionine biosynthetic process(GO:0009086)
0.0 0.1 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.0 0.1 GO:0021854 hypothalamus development(GO:0021854)
0.0 0.4 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.1 GO:0048511 rhythmic process(GO:0048511)
0.0 0.1 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.1 GO:0006405 RNA export from nucleus(GO:0006405)
0.0 0.1 GO:0016265 obsolete death(GO:0016265)
0.0 0.1 GO:0048840 otolith development(GO:0048840)
0.0 0.3 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.0 GO:0071428 rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.0 0.0 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.0 GO:0032627 interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667) positive regulation of interleukin-23 production(GO:0032747)
0.0 0.0 GO:2000309 activation of MAPK activity involved in innate immune response(GO:0035419) tumor necrosis factor (ligand) superfamily member 11 production(GO:0072535) regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000307) positive regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000309)
0.0 0.1 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.3 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 1.5 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.3 GO:0007162 negative regulation of cell adhesion(GO:0007162)
0.0 0.1 GO:0007140 male meiosis(GO:0007140)
0.0 0.0 GO:0042727 flavin-containing compound metabolic process(GO:0042726) flavin-containing compound biosynthetic process(GO:0042727)
0.0 0.2 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.2 GO:0006596 polyamine biosynthetic process(GO:0006596)
0.0 0.1 GO:0010824 regulation of centrosome duplication(GO:0010824)
0.0 0.1 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 0.1 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.0 0.1 GO:0060157 urinary bladder development(GO:0060157)
0.0 0.1 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.2 GO:0060334 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.1 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0 0.2 GO:0006825 copper ion transport(GO:0006825)
0.0 0.1 GO:0009650 UV protection(GO:0009650)
0.0 0.0 GO:0050821 protein stabilization(GO:0050821)
0.0 0.0 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.0 0.1 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.5 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 0.2 GO:0034504 protein localization to nucleus(GO:0034504)
0.0 0.0 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0 0.2 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.1 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 0.1 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.0 0.2 GO:0009154 purine ribonucleotide catabolic process(GO:0009154)
0.0 0.9 GO:0006119 oxidative phosphorylation(GO:0006119)
0.0 0.2 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.1 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.0 0.1 GO:0008228 opsonization(GO:0008228)
0.0 0.1 GO:0042354 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.3 GO:0032418 lysosome localization(GO:0032418)
0.0 0.2 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.7 GO:0022613 ribonucleoprotein complex biogenesis(GO:0022613)
0.0 0.1 GO:0070170 regulation of tooth mineralization(GO:0070170)
0.0 0.1 GO:0046488 phosphatidylinositol metabolic process(GO:0046488)
0.0 0.3 GO:0000087 mitotic M phase(GO:0000087)
0.0 0.3 GO:0042274 ribosomal small subunit biogenesis(GO:0042274)
0.0 0.0 GO:0090312 regulation of protein deacetylation(GO:0090311) positive regulation of protein deacetylation(GO:0090312)
0.0 0.2 GO:0032410 negative regulation of transporter activity(GO:0032410)
0.0 1.0 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.1 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.1 GO:0034644 cellular response to UV(GO:0034644)
0.0 0.1 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.1 GO:0070295 renal water absorption(GO:0070295)
0.0 3.9 GO:0008380 RNA splicing(GO:0008380)
0.0 0.1 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.0 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.0 GO:0007270 neuron-neuron synaptic transmission(GO:0007270)
0.0 0.1 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.0 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.0 0.1 GO:0009450 gamma-aminobutyric acid metabolic process(GO:0009448) gamma-aminobutyric acid catabolic process(GO:0009450)
0.0 0.0 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 0.1 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.4 GO:0021675 nerve development(GO:0021675)
0.0 0.0 GO:0032229 negative regulation of synaptic transmission, GABAergic(GO:0032229)
0.0 0.1 GO:0060736 prostate gland growth(GO:0060736)
0.0 0.0 GO:0032375 negative regulation of sterol transport(GO:0032372) negative regulation of cholesterol transport(GO:0032375)
0.0 0.2 GO:0007276 gamete generation(GO:0007276)
0.0 0.1 GO:0043534 blood vessel endothelial cell migration(GO:0043534)
0.0 0.2 GO:0051925 obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.0 0.2 GO:0031670 cellular response to nutrient(GO:0031670)
0.0 0.2 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 0.1 GO:0046697 decidualization(GO:0046697)
0.0 0.1 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.2 GO:0042438 melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438)
0.0 0.1 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.0 GO:0045338 farnesyl diphosphate metabolic process(GO:0045338)
0.0 0.0 GO:0015824 proline transport(GO:0015824)
0.0 0.0 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.0 0.2 GO:0030178 negative regulation of Wnt signaling pathway(GO:0030178)
0.0 0.1 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.1 GO:0015853 adenine transport(GO:0015853)
0.0 0.1 GO:0019228 neuronal action potential(GO:0019228)
0.0 0.2 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 1.3 GO:0008654 phospholipid biosynthetic process(GO:0008654)
0.0 0.0 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.1 GO:0000723 telomere maintenance(GO:0000723)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.4 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.3 1.3 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.3 2.2 GO:0070761 pre-snoRNP complex(GO:0070761)
0.3 3.2 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.2 0.7 GO:0032302 MutSbeta complex(GO:0032302)
0.2 0.6 GO:0031262 Ndc80 complex(GO:0031262)
0.2 4.3 GO:0042627 chylomicron(GO:0042627)
0.2 0.8 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
0.2 2.4 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.2 1.4 GO:0042575 DNA polymerase complex(GO:0042575)
0.2 1.9 GO:0043020 NADPH oxidase complex(GO:0043020)
0.2 1.8 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.2 1.5 GO:0070652 HAUS complex(GO:0070652)
0.1 0.4 GO:0000800 lateral element(GO:0000800)
0.1 0.9 GO:0019815 immunoglobulin complex(GO:0019814) B cell receptor complex(GO:0019815)
0.1 0.1 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.1 0.8 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 0.8 GO:0000300 obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.1 5.0 GO:0042645 mitochondrial nucleoid(GO:0042645)
0.1 0.3 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 0.3 GO:0033655 host(GO:0018995) host cell cytoplasm(GO:0030430) host cell part(GO:0033643) host intracellular part(GO:0033646) host cell cytoplasm part(GO:0033655) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.1 0.5 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 1.0 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.1 2.0 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 0.3 GO:0030018 Z disc(GO:0030018)
0.1 0.4 GO:0042405 nuclear inclusion body(GO:0042405)
0.1 1.5 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 0.9 GO:0010369 chromocenter(GO:0010369)
0.1 0.7 GO:0000796 condensin complex(GO:0000796)
0.1 0.4 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 0.2 GO:0043159 acrosomal matrix(GO:0043159)
0.1 0.7 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.1 0.5 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 1.8 GO:0005761 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.1 0.4 GO:0045179 apical cortex(GO:0045179)
0.1 0.3 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 0.3 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 0.8 GO:0005652 nuclear lamina(GO:0005652)
0.1 1.0 GO:0031941 filamentous actin(GO:0031941)
0.1 0.6 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 0.2 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 0.7 GO:0034451 centriolar satellite(GO:0034451)
0.1 0.2 GO:0043235 receptor complex(GO:0043235)
0.1 0.5 GO:0030681 nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.1 0.2 GO:0035189 Rb-E2F complex(GO:0035189)
0.1 1.0 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.2 GO:0005712 chiasma(GO:0005712) MutLbeta complex(GO:0032390)
0.0 0.2 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.1 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.2 GO:0045257 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.4 GO:0045120 pronucleus(GO:0045120)
0.0 0.2 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 1.0 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.2 GO:0031045 dense core granule(GO:0031045)
0.0 0.7 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 2.0 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 0.2 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.1 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 0.3 GO:0000346 transcription export complex(GO:0000346)
0.0 0.7 GO:0030057 desmosome(GO:0030057)
0.0 2.1 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 0.2 GO:0030894 replisome(GO:0030894) nuclear replisome(GO:0043601)
0.0 0.3 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 0.2 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 2.7 GO:0005643 nuclear pore(GO:0005643)
0.0 0.6 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 1.8 GO:0098687 chromosomal region(GO:0098687)
0.0 1.7 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.1 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.0 0.1 GO:0030914 STAGA complex(GO:0030914)
0.0 0.2 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 1.1 GO:0098636 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.1 GO:0042599 lamellar body(GO:0042599)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.2 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.1 GO:0042612 MHC protein complex(GO:0042611) MHC class I protein complex(GO:0042612)
0.0 1.3 GO:0000922 spindle pole(GO:0000922)
0.0 0.5 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.1 GO:0030686 90S preribosome(GO:0030686)
0.0 0.7 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.3 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.1 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.1 GO:0043198 dendritic shaft(GO:0043198)
0.0 2.1 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.2 GO:0031264 death-inducing signaling complex(GO:0031264) CD95 death-inducing signaling complex(GO:0031265)
0.0 0.1 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.3 GO:0016235 aggresome(GO:0016235)
0.0 0.3 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.2 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.0 0.2 GO:0009986 cell surface(GO:0009986)
0.0 0.3 GO:0046930 pore complex(GO:0046930)
0.0 0.1 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 0.6 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.2 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.1 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0 0.1 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.2 GO:0044452 nucleolar part(GO:0044452)
0.0 0.1 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.0 0.1 GO:0031673 H zone(GO:0031673)
0.0 0.2 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.5 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.8 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.1 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.9 GO:0005792 obsolete microsome(GO:0005792)
0.0 0.2 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.0 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.0 0.2 GO:0030673 axolemma(GO:0030673)
0.0 0.6 GO:0000786 nucleosome(GO:0000786)
0.0 0.6 GO:0030863 cortical cytoskeleton(GO:0030863)
0.0 0.1 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 1.0 GO:0000790 nuclear chromatin(GO:0000790)
0.0 0.3 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.0 0.1 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.4 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.4 GO:0016592 mediator complex(GO:0016592)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.4 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.2 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.2 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.2 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.7 GO:0005681 spliceosomal complex(GO:0005681)
0.0 0.0 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.8 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.0 0.1 GO:0005678 obsolete chromatin assembly complex(GO:0005678)
0.0 1.5 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 0.0 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.0 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.1 GO:0005844 polysome(GO:0005844)
0.0 2.5 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.1 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.2 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.1 GO:0016585 obsolete chromatin remodeling complex(GO:0016585)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.6 3.1 GO:0070363 mitochondrial light strand promoter sense binding(GO:0070363)
0.6 1.7 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.5 1.6 GO:0004122 cystathionine beta-synthase activity(GO:0004122)
0.4 1.6 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.4 3.1 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.3 1.1 GO:0016784 3-mercaptopyruvate sulfurtransferase activity(GO:0016784)
0.2 0.7 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.2 0.7 GO:0000404 heteroduplex DNA loop binding(GO:0000404) double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181)
0.2 1.7 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.2 0.8 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.2 1.6 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.2 1.0 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.2 0.8 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.2 2.9 GO:0004017 adenylate kinase activity(GO:0004017)
0.2 1.0 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.2 0.5 GO:0044549 GTP cyclohydrolase binding(GO:0044549)
0.2 0.5 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241) protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.2 0.7 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.2 0.5 GO:0015361 low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
0.2 1.0 GO:0030955 potassium ion binding(GO:0030955)
0.2 1.0 GO:0019238 cyclohydrolase activity(GO:0019238)
0.2 0.5 GO:0000156 phosphorelay response regulator activity(GO:0000156)
0.2 0.5 GO:0004917 interleukin-4 receptor activity(GO:0004913) interleukin-7 receptor activity(GO:0004917) interleukin-2 binding(GO:0019976)
0.1 0.6 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 0.4 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.1 1.1 GO:0004428 obsolete inositol or phosphatidylinositol kinase activity(GO:0004428)
0.1 0.4 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.1 0.6 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 1.7 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.1 0.5 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.1 1.3 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.1 0.9 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 0.4 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.1 0.6 GO:0070644 vitamin D response element binding(GO:0070644)
0.1 0.4 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 0.5 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 0.7 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.1 0.3 GO:0042296 ISG15 transferase activity(GO:0042296)
0.1 1.4 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 0.3 GO:0004603 phenylethanolamine N-methyltransferase activity(GO:0004603)
0.1 0.8 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.3 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.7 GO:0004849 uridine kinase activity(GO:0004849)
0.1 0.3 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.1 0.4 GO:0002060 purine nucleobase binding(GO:0002060)
0.1 0.4 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.1 0.9 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.1 6.0 GO:0003823 antigen binding(GO:0003823)
0.1 0.4 GO:0015350 methotrexate transporter activity(GO:0015350)
0.1 0.3 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 0.4 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.1 0.4 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.1 0.8 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 0.3 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.1 0.8 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.1 0.3 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.1 0.8 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 2.1 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.5 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 0.3 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.1 0.3 GO:0004756 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.1 0.6 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.1 0.4 GO:0016530 metallochaperone activity(GO:0016530)
0.1 0.6 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.1 0.2 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 2.2 GO:0070491 repressing transcription factor binding(GO:0070491)
0.1 0.3 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 0.5 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.1 0.1 GO:0032139 dinucleotide insertion or deletion binding(GO:0032139)
0.1 0.4 GO:0019237 centromeric DNA binding(GO:0019237)
0.1 0.4 GO:0004766 spermidine synthase activity(GO:0004766)
0.1 0.2 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.1 0.4 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 0.3 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 0.6 GO:0016004 phospholipase activator activity(GO:0016004)
0.1 0.3 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.1 0.3 GO:0016882 cyclo-ligase activity(GO:0016882)
0.1 0.1 GO:0060229 lipase activator activity(GO:0060229)
0.1 0.3 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.1 0.2 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1 0.7 GO:0017127 cholesterol transporter activity(GO:0017127)
0.1 0.3 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 0.4 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 0.2 GO:0016362 activin receptor activity, type II(GO:0016362)
0.1 0.3 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.1 0.2 GO:0042808 obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.1 0.4 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 0.3 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.1 0.2 GO:0003878 ATP citrate synthase activity(GO:0003878)
0.1 0.2 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.1 0.2 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.1 0.2 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.1 0.3 GO:0043175 RNA polymerase core enzyme binding(GO:0043175)
0.1 0.7 GO:0004526 ribonuclease P activity(GO:0004526)
0.1 0.9 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 0.3 GO:0019103 pyrimidine nucleotide binding(GO:0019103) deoxyribonucleotide binding(GO:0032552)
0.1 0.4 GO:0019789 SUMO transferase activity(GO:0019789)
0.1 0.5 GO:0045502 dynein binding(GO:0045502)
0.1 0.5 GO:0004969 histamine receptor activity(GO:0004969)
0.1 0.4 GO:0042562 hormone binding(GO:0042562)
0.1 1.1 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.1 2.6 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.1 0.1 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.1 0.3 GO:0008753 NADPH dehydrogenase (quinone) activity(GO:0008753)
0.1 0.2 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.1 0.3 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.1 0.2 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.1 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
0.0 0.3 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.3 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.2 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.1 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.0 0.1 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0 0.2 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.0 0.6 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.3 GO:0032190 acrosin binding(GO:0032190)
0.0 0.1 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.5 GO:0061659 ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0 0.3 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.9 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.1 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.3 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.1 GO:0004960 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.0 1.4 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)
0.0 0.6 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.7 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 1.4 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.0 0.2 GO:0033981 D-dopachrome decarboxylase activity(GO:0033981)
0.0 0.5 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0 0.3 GO:0004340 glucokinase activity(GO:0004340)
0.0 1.2 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.2 GO:0048039 succinate dehydrogenase activity(GO:0000104) ubiquinone binding(GO:0048039)
0.0 0.0 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.3 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.1 GO:0017163 obsolete basal transcription repressor activity(GO:0017163)
0.0 0.2 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.5 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.1 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.1 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.3 GO:0030250 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0 0.4 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.1 GO:0008934 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.3 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.1 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.2 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.0 0.5 GO:0015926 glucosidase activity(GO:0015926)
0.0 0.1 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.1 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.0 0.3 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.1 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 0.1 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 0.2 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.5 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.0 0.4 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.1 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.0 0.4 GO:0043176 amine binding(GO:0043176)
0.0 0.2 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.0 1.3 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 1.7 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.4 GO:0060590 ATPase regulator activity(GO:0060590)
0.0 0.2 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 0.1 GO:0004738 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.1 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 0.1 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.1 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.0 0.2 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.1 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.3 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.6 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.4 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.4 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.2 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.1 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.1 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.2 GO:0001228 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.1 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.1 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.0 0.3 GO:0015288 porin activity(GO:0015288)
0.0 0.3 GO:0031489 myosin V binding(GO:0031489)
0.0 0.2 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.6 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 0.1 GO:0042020 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.0 0.1 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.0 1.1 GO:0001948 glycoprotein binding(GO:0001948)
0.0 0.1 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.3 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.4 GO:0031014 troponin T binding(GO:0031014)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.1 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.9 GO:0004629 phospholipase C activity(GO:0004629)
0.0 0.3 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.7 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 1.2 GO:0004527 exonuclease activity(GO:0004527)
0.0 0.2 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0 0.3 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.4 GO:0005537 mannose binding(GO:0005537)
0.0 0.1 GO:0030350 iron-responsive element binding(GO:0030350)
0.0 0.3 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.3 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.0 0.3 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.4 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.0 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.1 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.1 GO:0071566 UFM1 activating enzyme activity(GO:0071566)
0.0 0.1 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.0 0.2 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.9 GO:0003702 obsolete RNA polymerase II transcription factor activity(GO:0003702)
0.0 0.2 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.1 GO:0005496 steroid binding(GO:0005496)
0.0 0.4 GO:0019213 deacetylase activity(GO:0019213)
0.0 0.2 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.4 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.1 GO:0019981 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.0 0.1 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.0 0.1 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.4 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 0.7 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.1 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.1 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.5 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 0.1 GO:0016997 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0 0.2 GO:0010181 FMN binding(GO:0010181)
0.0 0.0 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.0 0.2 GO:0070513 death domain binding(GO:0070513)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.1 GO:0032145 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.0 0.2 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0 0.1 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.2 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.2 GO:0001619 obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619)
0.0 0.3 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.1 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.1 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.5 GO:0030552 cAMP binding(GO:0030552)
0.0 0.1 GO:0047150 S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898) betaine-homocysteine S-methyltransferase activity(GO:0047150)
0.0 0.1 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.0 0.5 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.0 0.0 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.3 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.1 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.2 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.5 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.2 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0 0.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 3.3 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.2 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.0 0.6 GO:0051087 chaperone binding(GO:0051087)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.0 0.1 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 0.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.1 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.2 GO:0000049 tRNA binding(GO:0000049)
0.0 0.1 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.1 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.0 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.3 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.1 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.1 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.6 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.0 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.7 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.1 GO:0001848 complement binding(GO:0001848)
0.0 0.1 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.2 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.0 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.1 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.0 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.1 GO:0004540 ribonuclease activity(GO:0004540)
0.0 0.2 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.1 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.3 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.0 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 0.2 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 1.0 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.3 GO:0016875 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.0 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.0 0.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.5 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.0 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.5 GO:0031072 heat shock protein binding(GO:0031072)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 ST_B_CELL_ANTIGEN_RECEPTOR B Cell Antigen Receptor
0.0 0.9 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 2.4 ST_T_CELL_SIGNAL_TRANSDUCTION T Cell Signal Transduction
0.0 1.6 ST_GA13_PATHWAY G alpha 13 Pathway
0.0 0.1 ST_JAK_STAT_PATHWAY Jak-STAT Pathway
0.0 0.1 ST_PAC1_RECEPTOR_PATHWAY PAC1 Receptor Pathway
0.0 1.0 ST_P38_MAPK_PATHWAY p38 MAPK Pathway
0.0 0.1 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 0.3 SA_G1_AND_S_PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.3 ST_INTERLEUKIN_4_PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.1 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.1 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.1 ST_STAT3_PATHWAY STAT3 Pathway