Motif ID: MNT_HEY1_HEY2

Z-value: 1.208

Transcription factors associated with MNT_HEY1_HEY2:

Gene SymbolEntrez IDGene Name
HEY1 ENSG00000164683.12 HEY1
HEY2 ENSG00000135547.4 HEY2
MNT ENSG00000070444.10 MNT






Network of associatons between targets according to the STRING database.



First level regulatory network of MNT_HEY1_HEY2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_150675372 2.281 ENST00000262186.5
KCNH2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr17_+_40440481 1.908 ENST00000590726.2
ENST00000452307.2
ENST00000444283.1
ENST00000588868.1
STAT5A



signal transducer and activator of transcription 5A



chr19_-_41903161 1.782 ENST00000602129.1
ENST00000593771.1
ENST00000596905.1
ENST00000221233.4
EXOSC5



exosome component 5



chr13_-_36788718 1.692 ENST00000317764.6
ENST00000379881.3
SOHLH2

spermatogenesis and oogenesis specific basic helix-loop-helix 2

chr8_+_142402089 1.576 ENST00000521578.1
ENST00000520105.1
ENST00000523147.1
PTP4A3


protein tyrosine phosphatase type IVA, member 3


chr7_-_103629963 1.571 ENST00000428762.1
ENST00000343529.5
ENST00000424685.2
RELN


reelin


chr2_-_220083692 1.538 ENST00000265316.3
ABCB6
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr16_+_29467127 1.478 ENST00000344620.6
SULT1A4
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4
chr2_-_220083671 1.477 ENST00000439002.2
ABCB6
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr4_+_40198527 1.363 ENST00000381799.5
RHOH
ras homolog family member H
chr22_-_36903101 1.332 ENST00000397224.4
FOXRED2
FAD-dependent oxidoreductase domain containing 2
chr1_-_26232951 1.316 ENST00000426559.2
ENST00000455785.2
STMN1

stathmin 1

chr5_+_95066823 1.281 ENST00000506817.1
ENST00000379982.3
RHOBTB3

Rho-related BTB domain containing 3

chr15_-_83316254 1.262 ENST00000567678.1
ENST00000450751.2
CPEB1

cytoplasmic polyadenylation element binding protein 1

chr19_-_46974664 1.242 ENST00000438932.2
PNMAL1
paraneoplastic Ma antigen family-like 1
chr19_-_46974741 1.214 ENST00000313683.10
ENST00000602246.1
PNMAL1

paraneoplastic Ma antigen family-like 1

chr11_-_73694346 1.192 ENST00000310473.3
UCP2
uncoupling protein 2 (mitochondrial, proton carrier)
chr18_+_32556892 1.159 ENST00000591734.1
ENST00000413393.1
ENST00000589180.1
ENST00000587359.1
MAPRE2



microtubule-associated protein, RP/EB family, member 2



chrX_+_102469997 1.152 ENST00000372695.5
ENST00000372691.3
BEX4

brain expressed, X-linked 4

chr5_+_126112794 1.148 ENST00000261366.5
ENST00000395354.1
LMNB1

lamin B1

chr6_-_39197226 1.134 ENST00000359534.3
KCNK5
potassium channel, subfamily K, member 5
chr7_+_150759634 1.134 ENST00000392826.2
ENST00000461735.1
SLC4A2

solute carrier family 4 (anion exchanger), member 2

chr5_+_43120985 1.129 ENST00000515326.1
ZNF131
zinc finger protein 131
chr15_-_72668805 1.083 ENST00000268097.5
HEXA
hexosaminidase A (alpha polypeptide)
chr5_+_138609441 1.078 ENST00000509990.1
ENST00000506147.1
ENST00000512107.1
MATR3


matrin 3


chr11_+_67159416 1.058 ENST00000307980.2
ENST00000544620.1
RAD9A

RAD9 homolog A (S. pombe)

chr12_-_58146048 1.048 ENST00000547281.1
ENST00000546489.1
ENST00000552388.1
ENST00000540325.1
ENST00000312990.6
CDK4




cyclin-dependent kinase 4




chr10_-_44070016 1.048 ENST00000374446.2
ENST00000426961.1
ENST00000535642.1
ZNF239


zinc finger protein 239


chr6_+_31865552 1.031 ENST00000469372.1
ENST00000497706.1
C2

complement component 2

chr19_+_50887585 1.020 ENST00000440232.2
ENST00000601098.1
ENST00000599857.1
ENST00000593887.1
POLD1



polymerase (DNA directed), delta 1, catalytic subunit



chr17_+_55163075 1.012 ENST00000571629.1
ENST00000570423.1
ENST00000575186.1
ENST00000573085.1
ENST00000572814.1
AKAP1




A kinase (PRKA) anchor protein 1




chr11_-_57283159 1.004 ENST00000533263.1
ENST00000278426.3
SLC43A1

solute carrier family 43 (amino acid system L transporter), member 1

chr6_-_153304148 0.961 ENST00000229758.3
FBXO5
F-box protein 5
chr19_-_5719860 0.947 ENST00000590729.1
LONP1
lon peptidase 1, mitochondrial
chr16_+_2867164 0.921 ENST00000455114.1
ENST00000450020.3
PRSS21

protease, serine, 21 (testisin)

chr2_-_220083076 0.917 ENST00000295750.4
ABCB6
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr22_-_36903069 0.903 ENST00000216187.6
ENST00000423980.1
FOXRED2

FAD-dependent oxidoreductase domain containing 2

chr19_+_1067271 0.871 ENST00000536472.1
ENST00000590214.1
HMHA1

histocompatibility (minor) HA-1

chr12_-_58146128 0.858 ENST00000551800.1
ENST00000549606.1
ENST00000257904.6
CDK4


cyclin-dependent kinase 4


chr1_+_11333245 0.852 ENST00000376810.5
UBIAD1
UbiA prenyltransferase domain containing 1
chr1_+_12123414 0.847 ENST00000263932.2
TNFRSF8
tumor necrosis factor receptor superfamily, member 8
chr16_+_30205754 0.832 ENST00000354723.6
ENST00000355544.5
SULT1A3

sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3

chr1_-_21995794 0.822 ENST00000542643.2
ENST00000374765.4
ENST00000317967.7
RAP1GAP


RAP1 GTPase activating protein


chr6_+_13182751 0.813 ENST00000415087.1
PHACTR1
phosphatase and actin regulator 1
chr6_+_30524663 0.808 ENST00000376560.3
PRR3
proline rich 3
chr6_-_31763721 0.801 ENST00000375663.3
VARS
valyl-tRNA synthetase
chr16_-_23521710 0.799 ENST00000562117.1
ENST00000567468.1
ENST00000562944.1
ENST00000309859.4
GGA2



golgi-associated, gamma adaptin ear containing, ARF binding protein 2



chr17_-_18266660 0.799 ENST00000582653.1
ENST00000352886.6
SHMT1

serine hydroxymethyltransferase 1 (soluble)

chr12_-_103310987 0.794 ENST00000307000.2
PAH
phenylalanine hydroxylase
chr15_-_83316711 0.792 ENST00000568128.1
CPEB1
cytoplasmic polyadenylation element binding protein 1
chr18_+_9136758 0.787 ENST00000383440.2
ENST00000262126.4
ENST00000577992.1
ANKRD12


ankyrin repeat domain 12


chr17_-_34890709 0.785 ENST00000544606.1
MYO19
myosin XIX
chr11_-_118972575 0.780 ENST00000432443.2
DPAGT1
dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
chr19_-_5720123 0.772 ENST00000587365.1
ENST00000585374.1
ENST00000593119.1
LONP1


lon peptidase 1, mitochondrial


chr7_+_116593568 0.771 ENST00000446490.1
ST7
suppression of tumorigenicity 7
chr13_+_50656307 0.769 ENST00000378180.4
DLEU1
deleted in lymphocytic leukemia 1 (non-protein coding)
chr11_+_34127142 0.759 ENST00000257829.3
ENST00000531159.2
NAT10

N-acetyltransferase 10 (GCN5-related)

chr16_-_81129845 0.756 ENST00000569885.1
ENST00000566566.1
GCSH

glycine cleavage system protein H (aminomethyl carrier)

chr22_-_19419205 0.752 ENST00000340170.4
ENST00000263208.5
HIRA

histone cell cycle regulator

chr6_-_167369612 0.751 ENST00000507747.1
RP11-514O12.4
RP11-514O12.4
chr6_-_31864977 0.747 ENST00000395728.3
ENST00000375528.4
EHMT2

euchromatic histone-lysine N-methyltransferase 2

chr6_+_160390102 0.740 ENST00000356956.1
IGF2R
insulin-like growth factor 2 receptor
chr1_+_26496362 0.740 ENST00000374266.5
ENST00000270812.5
ZNF593

zinc finger protein 593

chr22_-_22221658 0.735 ENST00000544786.1
MAPK1
mitogen-activated protein kinase 1
chr2_+_46926048 0.726 ENST00000306503.5
SOCS5
suppressor of cytokine signaling 5
chr7_-_95951334 0.721 ENST00000265631.5
SLC25A13
solute carrier family 25 (aspartate/glutamate carrier), member 13
chr7_-_95951432 0.718 ENST00000416240.2
SLC25A13
solute carrier family 25 (aspartate/glutamate carrier), member 13
chr8_-_95908902 0.712 ENST00000520509.1
CCNE2
cyclin E2
chr12_+_117176090 0.706 ENST00000257575.4
ENST00000407967.3
ENST00000392549.2
RNFT2


ring finger protein, transmembrane 2


chr21_+_45527171 0.693 ENST00000291576.7
ENST00000456705.1
PWP2

PWP2 periodic tryptophan protein homolog (yeast)

chr15_-_72668185 0.691 ENST00000457859.2
ENST00000566304.1
ENST00000567159.1
ENST00000429918.2
HEXA



hexosaminidase A (alpha polypeptide)



chrX_+_37545012 0.688 ENST00000378616.3
XK
X-linked Kx blood group (McLeod syndrome)
chr20_+_55966444 0.687 ENST00000356208.5
ENST00000440234.2
RBM38

RNA binding motif protein 38

chr17_-_47492164 0.685 ENST00000512041.2
ENST00000446735.1
ENST00000504124.1
PHB


prohibitin


chr7_+_150065879 0.683 ENST00000478789.1
ENST00000397281.2
ENST00000444957.1
ENST00000466559.1
ENST00000489432.2
ENST00000475514.1
ENST00000482680.1
ENST00000488943.1
ENST00000518514.1
ZNF775
REPIN1







zinc finger protein 775
replication initiator 1







chr16_-_28634874 0.683 ENST00000395609.1
ENST00000350842.4
SULT1A1

sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1

chr17_-_34890665 0.679 ENST00000586007.1
MYO19
myosin XIX
chr3_-_150481164 0.678 ENST00000312960.3
SIAH2
siah E3 ubiquitin protein ligase 2
chr13_+_103451399 0.678 ENST00000257336.1
ENST00000448849.2
BIVM

basic, immunoglobulin-like variable motif containing

chr9_+_71320596 0.675 ENST00000265382.3
PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr1_+_116915855 0.668 ENST00000295598.5
ATP1A1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr6_-_151773232 0.662 ENST00000444024.1
ENST00000367303.4
RMND1

required for meiotic nuclear division 1 homolog (S. cerevisiae)

chr7_+_116593433 0.657 ENST00000323984.3
ENST00000393449.1
ST7

suppression of tumorigenicity 7

chrX_+_24711997 0.657 ENST00000379068.3
ENST00000379059.3
POLA1

polymerase (DNA directed), alpha 1, catalytic subunit

chr11_-_61684962 0.652 ENST00000394836.2
RAB3IL1
RAB3A interacting protein (rabin3)-like 1
chr2_-_220042825 0.649 ENST00000409789.1
CNPPD1
cyclin Pas1/PHO80 domain containing 1
chr17_+_5185552 0.644 ENST00000262477.6
ENST00000408982.2
ENST00000575991.1
ENST00000537505.1
ENST00000546142.2
RABEP1




rabaptin, RAB GTPase binding effector protein 1




chr11_+_35684288 0.640 ENST00000299413.5
TRIM44
tripartite motif containing 44
chr19_+_1067144 0.638 ENST00000313093.2
HMHA1
histocompatibility (minor) HA-1
chr12_-_122751002 0.628 ENST00000267199.4
VPS33A
vacuolar protein sorting 33 homolog A (S. cerevisiae)
chr12_+_113623325 0.618 ENST00000549621.1
ENST00000548278.1
ENST00000552495.1
C12orf52


RBPJ interacting and tubulin associated 1


chr4_-_57301748 0.617 ENST00000264220.2
PPAT
phosphoribosyl pyrophosphate amidotransferase
chr2_+_88991162 0.616 ENST00000283646.4
RPIA
ribose 5-phosphate isomerase A
chr1_+_33116743 0.613 ENST00000414241.3
ENST00000373493.5
RBBP4

retinoblastoma binding protein 4

chr2_+_216176761 0.611 ENST00000540518.1
ENST00000435675.1
ATIC

5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase

chr12_-_6716534 0.607 ENST00000544484.1
ENST00000309577.6
ENST00000357008.2
CHD4


chromodomain helicase DNA binding protein 4


chr12_-_6716569 0.602 ENST00000544040.1
ENST00000545942.1
CHD4

chromodomain helicase DNA binding protein 4

chr22_-_30987837 0.597 ENST00000335214.6
PES1
pescadillo ribosomal biogenesis factor 1
chr10_-_69597915 0.595 ENST00000225171.2
DNAJC12
DnaJ (Hsp40) homolog, subfamily C, member 12
chr11_-_57282349 0.594 ENST00000528450.1
SLC43A1
solute carrier family 43 (amino acid system L transporter), member 1
chr11_-_63933504 0.587 ENST00000255681.6
MACROD1
MACRO domain containing 1
chr6_+_135502408 0.586 ENST00000341911.5
ENST00000442647.2
ENST00000316528.8
MYB


v-myb avian myeloblastosis viral oncogene homolog


chr15_+_45315302 0.585 ENST00000267814.9
SORD
sorbitol dehydrogenase
chr5_+_65440032 0.585 ENST00000334121.6
SREK1
splicing regulatory glutamine/lysine-rich protein 1
chr6_+_135502466 0.580 ENST00000367814.4
MYB
v-myb avian myeloblastosis viral oncogene homolog
chr1_-_26232522 0.579 ENST00000399728.1
STMN1
stathmin 1
chr2_+_216176540 0.578 ENST00000236959.9
ATIC
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr6_-_153304697 0.576 ENST00000367241.3
FBXO5
F-box protein 5
chr1_-_26233423 0.575 ENST00000357865.2
STMN1
stathmin 1
chr4_-_103266355 0.574 ENST00000424970.2
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr7_-_92465868 0.568 ENST00000424848.2
CDK6
cyclin-dependent kinase 6
chr3_+_52719936 0.568 ENST00000418458.1
ENST00000394799.2
GNL3

guanine nucleotide binding protein-like 3 (nucleolar)

chr11_-_85779786 0.567 ENST00000356360.5
PICALM
phosphatidylinositol binding clathrin assembly protein
chr17_-_34890732 0.567 ENST00000268852.9
MYO19
myosin XIX
chr2_-_40006289 0.566 ENST00000260619.6
ENST00000454352.2
THUMPD2

THUMP domain containing 2

chr20_+_35201857 0.565 ENST00000373874.2
TGIF2
TGFB-induced factor homeobox 2
chr1_+_9599540 0.565 ENST00000302692.6
SLC25A33
solute carrier family 25 (pyrimidine nucleotide carrier), member 33
chr9_+_131709966 0.565 ENST00000372577.2
NUP188
nucleoporin 188kDa
chr10_+_22610124 0.561 ENST00000376663.3
BMI1
BMI1 polycomb ring finger oncogene
chr12_+_64845660 0.558 ENST00000331710.5
TBK1
TANK-binding kinase 1
chr19_-_47734448 0.557 ENST00000439096.2
BBC3
BCL2 binding component 3
chr6_+_44191290 0.555 ENST00000371755.3
ENST00000371740.5
ENST00000371731.1
ENST00000393841.1
SLC29A1



solute carrier family 29 (equilibrative nucleoside transporter), member 1



chr20_+_48552908 0.554 ENST00000244061.2
RNF114
ring finger protein 114
chr2_-_40006357 0.554 ENST00000505747.1
THUMPD2
THUMP domain containing 2
chr19_+_10812108 0.553 ENST00000250237.5
ENST00000592254.1
QTRT1

queuine tRNA-ribosyltransferase 1

chr15_+_52311398 0.551 ENST00000261845.5
MAPK6
mitogen-activated protein kinase 6
chr5_-_175964366 0.549 ENST00000274811.4
RNF44
ring finger protein 44
chr17_+_35306175 0.547 ENST00000225402.5
AATF
apoptosis antagonizing transcription factor
chr7_+_89975979 0.547 ENST00000257659.8
ENST00000222511.6
ENST00000417207.1
GTPBP10


GTP-binding protein 10 (putative)


chr16_+_2570340 0.547 ENST00000568263.1
ENST00000293971.6
ENST00000302956.4
ENST00000413459.3
ENST00000566706.1
ENST00000569879.1
AMDHD2





amidohydrolase domain containing 2





chr7_+_75677354 0.546 ENST00000461263.2
ENST00000315758.5
ENST00000443006.1
MDH2


malate dehydrogenase 2, NAD (mitochondrial)


chrX_-_100604184 0.542 ENST00000372902.3
TIMM8A
translocase of inner mitochondrial membrane 8 homolog A (yeast)
chr10_-_69597810 0.530 ENST00000483798.2
DNAJC12
DnaJ (Hsp40) homolog, subfamily C, member 12
chr3_-_47517302 0.528 ENST00000441517.2
ENST00000545718.1
SCAP

SREBF chaperone

chrX_-_57147748 0.528 ENST00000374910.3
SPIN2B
spindlin family, member 2B
chr16_+_770975 0.526 ENST00000569529.1
ENST00000564000.1
ENST00000219535.3
FAM173A


family with sequence similarity 173, member A


chr17_-_47492236 0.524 ENST00000434917.2
ENST00000300408.3
ENST00000511832.1
ENST00000419140.2
PHB



prohibitin



chr6_-_8102714 0.523 ENST00000502429.1
ENST00000429723.2
ENST00000507463.1
ENST00000379715.5
EEF1E1



eukaryotic translation elongation factor 1 epsilon 1



chr22_-_30987849 0.521 ENST00000402284.3
ENST00000354694.7
PES1

pescadillo ribosomal biogenesis factor 1

chr11_-_119252359 0.520 ENST00000455332.2
USP2
ubiquitin specific peptidase 2
chrX_-_48776292 0.518 ENST00000376509.4
PIM2
pim-2 oncogene
chr1_+_12227035 0.515 ENST00000376259.3
ENST00000536782.1
TNFRSF1B

tumor necrosis factor receptor superfamily, member 1B

chr6_+_10694900 0.514 ENST00000379568.3
PAK1IP1
PAK1 interacting protein 1
chr17_-_61850894 0.513 ENST00000403162.3
ENST00000582252.1
ENST00000225726.5
CCDC47


coiled-coil domain containing 47


chrX_-_57147902 0.511 ENST00000275988.5
ENST00000434397.1
ENST00000333933.3
ENST00000374912.5
SPIN2B



spindlin family, member 2B



chr4_-_103266626 0.510 ENST00000356736.4
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr17_+_76311791 0.509 ENST00000586321.1
AC061992.2
AC061992.2
chrX_+_115567767 0.509 ENST00000371900.4
SLC6A14
solute carrier family 6 (amino acid transporter), member 14
chr5_+_70883178 0.508 ENST00000323375.8
MCCC2
methylcrotonoyl-CoA carboxylase 2 (beta)
chr2_+_111878483 0.507 ENST00000308659.8
ENST00000357757.2
ENST00000393253.2
ENST00000337565.5
ENST00000393256.3
BCL2L11




BCL2-like 11 (apoptosis facilitator)




chr21_+_45209394 0.501 ENST00000497547.1
RRP1
ribosomal RNA processing 1
chr7_+_152456904 0.499 ENST00000537264.1
ACTR3B
ARP3 actin-related protein 3 homolog B (yeast)
chr5_+_43603229 0.498 ENST00000344920.4
ENST00000512996.2
NNT

nicotinamide nucleotide transhydrogenase

chr6_+_44191507 0.497 ENST00000371724.1
ENST00000371713.1
SLC29A1

solute carrier family 29 (equilibrative nucleoside transporter), member 1

chr12_+_57624085 0.493 ENST00000553474.1
SHMT2
serine hydroxymethyltransferase 2 (mitochondrial)
chr6_-_167370049 0.491 ENST00000366855.6
ENST00000508775.1
RNASET2

ribonuclease T2

chr11_-_85779971 0.491 ENST00000393346.3
PICALM
phosphatidylinositol binding clathrin assembly protein
chr14_-_20923195 0.490 ENST00000206542.4
OSGEP
O-sialoglycoprotein endopeptidase
chr8_-_103424916 0.489 ENST00000220959.4
UBR5
ubiquitin protein ligase E3 component n-recognin 5
chr8_-_103425047 0.489 ENST00000520539.1
UBR5
ubiquitin protein ligase E3 component n-recognin 5
chrX_+_108780347 0.486 ENST00000372103.1
NXT2
nuclear transport factor 2-like export factor 2
chr2_-_148778258 0.486 ENST00000392857.5
ENST00000457954.1
ENST00000392858.1
ENST00000542387.1
ORC4



origin recognition complex, subunit 4



chr17_-_18266797 0.484 ENST00000316694.3
ENST00000539052.1
SHMT1

serine hydroxymethyltransferase 1 (soluble)

chr19_+_1067492 0.484 ENST00000586866.1
HMHA1
histocompatibility (minor) HA-1
chr18_+_12947981 0.482 ENST00000262124.11
SEH1L
SEH1-like (S. cerevisiae)
chr5_-_131132658 0.482 ENST00000511848.1
ENST00000510461.1
ENST00000514667.1
FNIP1

CTC-432M15.3
folliculin interacting protein 1

Folliculin-interacting protein 1
chr11_-_119252425 0.481 ENST00000260187.2
USP2
ubiquitin specific peptidase 2
chr1_-_154193009 0.480 ENST00000368518.1
ENST00000368519.1
ENST00000368521.5
C1orf43


chromosome 1 open reading frame 43


chrX_+_151867214 0.480 ENST00000329342.5
ENST00000412733.1
ENST00000457643.1
MAGEA6


melanoma antigen family A, 6


chr19_+_1275917 0.480 ENST00000469144.1
C19orf24
chromosome 19 open reading frame 24
chr11_+_65479702 0.480 ENST00000530446.1
ENST00000534104.1
ENST00000530605.1
ENST00000528198.1
ENST00000531880.1
ENST00000534650.1
KAT5





K(lysine) acetyltransferase 5





chr8_-_30585439 0.479 ENST00000221130.5
GSR
glutathione reductase
chr2_+_68384976 0.478 ENST00000263657.2
PNO1
partner of NOB1 homolog (S. cerevisiae)
chr17_-_7137582 0.477 ENST00000575756.1
ENST00000575458.1
DVL2

dishevelled segment polarity protein 2

chr20_+_35201993 0.476 ENST00000373872.4
TGIF2
TGFB-induced factor homeobox 2
chr10_-_11653753 0.475 ENST00000609104.1
USP6NL
USP6 N-terminal like
chr18_+_2655692 0.474 ENST00000320876.6
SMCHD1
structural maintenance of chromosomes flexible hinge domain containing 1
chr9_-_19127474 0.473 ENST00000380465.3
ENST00000380464.3
ENST00000411567.1
ENST00000276914.2
PLIN2



perilipin 2



chrX_-_57164058 0.472 ENST00000374906.3
SPIN2A
spindlin family, member 2A
chr5_+_138609782 0.471 ENST00000361059.2
ENST00000514694.1
ENST00000504203.1
ENST00000502929.1
ENST00000394800.2
ENST00000509644.1
ENST00000505016.1
MATR3






matrin 3






chr18_+_12948000 0.471 ENST00000585730.1
ENST00000399892.2
ENST00000589446.1
ENST00000587761.1
SEH1L



SEH1-like (S. cerevisiae)



chr19_-_5720248 0.468 ENST00000360614.3
LONP1
lon peptidase 1, mitochondrial
chr19_-_33793430 0.468 ENST00000498907.2
CEBPA
CCAAT/enhancer binding protein (C/EBP), alpha
chr17_-_18266765 0.467 ENST00000354098.3
SHMT1
serine hydroxymethyltransferase 1 (soluble)
chr7_+_94537542 0.466 ENST00000433881.1
PPP1R9A
protein phosphatase 1, regulatory subunit 9A
chrX_+_16804544 0.465 ENST00000380122.5
ENST00000398155.4
TXLNG

taxilin gamma

chr9_+_71320557 0.465 ENST00000541509.1
PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr5_+_70883117 0.464 ENST00000340941.6
MCCC2
methylcrotonoyl-CoA carboxylase 2 (beta)
chr5_+_43602750 0.464 ENST00000505678.2
ENST00000512422.1
ENST00000264663.5
NNT


nicotinamide nucleotide transhydrogenase


chr6_+_127588020 0.462 ENST00000309649.3
ENST00000610162.1
ENST00000610153.1
ENST00000608991.1
ENST00000480444.1
RNF146




ring finger protein 146




chr19_+_59055814 0.460 ENST00000594806.1
ENST00000253024.5
ENST00000341753.6
TRIM28


tripartite motif containing 28


chr22_+_18593446 0.459 ENST00000316027.6
TUBA8
tubulin, alpha 8
chrX_+_108780062 0.459 ENST00000372106.1
NXT2
nuclear transport factor 2-like export factor 2
chr17_-_76124711 0.454 ENST00000306591.7
ENST00000590602.1
TMC6

transmembrane channel-like 6

chr17_-_76124812 0.446 ENST00000592063.1
ENST00000589271.1
ENST00000322933.4
ENST00000589553.1
TMC6



transmembrane channel-like 6



chr19_+_7587491 0.444 ENST00000264079.6
MCOLN1
mucolipin 1
chr11_+_65029421 0.444 ENST00000541089.1
POLA2
polymerase (DNA directed), alpha 2, accessory subunit
chr18_+_32621324 0.441 ENST00000300249.5
ENST00000538170.2
ENST00000588910.1
MAPRE2


microtubule-associated protein, RP/EB family, member 2


chr2_-_10588630 0.433 ENST00000234111.4
ODC1
ornithine decarboxylase 1
chr6_-_17706618 0.429 ENST00000262077.2
ENST00000537253.1
NUP153

nucleoporin 153kDa


Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.9 GO:1990170 detoxification of cadmium ion(GO:0071585) stress response to cadmium ion(GO:1990170)
0.7 2.2 GO:0070407 oxidation-dependent protein catabolic process(GO:0070407)
0.6 1.9 GO:0046449 allantoin metabolic process(GO:0000255) mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.6 1.7 GO:0006273 lagging strand elongation(GO:0006273)
0.4 3.1 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.4 1.5 GO:0000212 meiotic spindle organization(GO:0000212)
0.4 1.4 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.4 1.1 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.3 1.0 GO:0019858 cytosine metabolic process(GO:0019858)
0.3 1.2 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.3 1.1 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.3 0.8 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.3 1.0 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.3 2.0 GO:0006188 IMP biosynthetic process(GO:0006188) IMP metabolic process(GO:0046040)
0.3 1.0 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.2 2.1 GO:0050884 neuromuscular process controlling posture(GO:0050884)
0.2 1.8 GO:0015862 uridine transport(GO:0015862)
0.2 0.8 GO:0019348 polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.2 1.5 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.2 1.9 GO:0021800 cerebral cortex tangential migration(GO:0021800)
0.2 1.0 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.2 2.7 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.2 0.5 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.2 0.5 GO:0043371 negative regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043371) negative regulation of T-helper cell differentiation(GO:0045623) negative regulation of CD4-positive, alpha-beta T cell activation(GO:2000515)
0.2 0.8 GO:0010508 positive regulation of autophagy(GO:0010508)
0.2 0.7 GO:0040016 embryonic cleavage(GO:0040016)
0.2 1.0 GO:0006552 leucine catabolic process(GO:0006552)
0.2 1.0 GO:0006999 nuclear pore organization(GO:0006999)
0.2 1.4 GO:0018126 protein hydroxylation(GO:0018126)
0.2 0.5 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.1 0.7 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.1 0.6 GO:0000966 RNA 5'-end processing(GO:0000966)
0.1 0.4 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.1 0.4 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
0.1 0.4 GO:0061117 negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of cardiac muscle tissue development(GO:0055026) negative regulation of cardiac muscle cell proliferation(GO:0060044) negative regulation of heart growth(GO:0061117)
0.1 0.7 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1 1.2 GO:0006546 glycine catabolic process(GO:0006546)
0.1 0.5 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.1 0.4 GO:0034626 fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.5 GO:0001575 globoside metabolic process(GO:0001575)
0.1 0.5 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.1 1.1 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.1 0.3 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.1 1.2 GO:0000076 DNA replication checkpoint(GO:0000076)
0.1 0.9 GO:0045008 depyrimidination(GO:0045008)
0.1 0.3 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.1 0.5 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.1 0.3 GO:0045618 positive regulation of keratinocyte differentiation(GO:0045618)
0.1 0.4 GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.1 0.7 GO:0021903 rostrocaudal neural tube patterning(GO:0021903)
0.1 0.5 GO:1901984 negative regulation of histone acetylation(GO:0035067) negative regulation of protein acetylation(GO:1901984) negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.1 0.3 GO:0043418 cysteine biosynthetic process from serine(GO:0006535) homoserine metabolic process(GO:0009092) cysteine biosynthetic process via cystathionine(GO:0019343) transsulfuration(GO:0019346) homocysteine catabolic process(GO:0043418)
0.1 0.4 GO:0034723 DNA replication-dependent nucleosome organization(GO:0034723)
0.1 0.6 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.1 0.6 GO:0009113 purine nucleobase biosynthetic process(GO:0009113)
0.1 0.7 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 1.3 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 0.3 GO:0042744 hydrogen peroxide metabolic process(GO:0042743) hydrogen peroxide catabolic process(GO:0042744)
0.1 0.9 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
0.1 0.9 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.3 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.1 0.3 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.1 2.4 GO:0036503 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433) ERAD pathway(GO:0036503)
0.1 2.5 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.1 0.4 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.1 0.2 GO:0070445 Fc receptor mediated stimulatory signaling pathway(GO:0002431) regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369) oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445) positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.1 0.5 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.1 0.8 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.1 1.7 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.1 0.2 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.1 2.2 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.1 0.4 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.1 0.6 GO:0046174 polyol catabolic process(GO:0046174)
0.1 1.5 GO:0009812 flavonoid metabolic process(GO:0009812)
0.1 0.2 GO:0003289 septum primum development(GO:0003284) atrial septum primum morphogenesis(GO:0003289)
0.1 0.6 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.1 0.2 GO:0002082 regulation of oxidative phosphorylation(GO:0002082)
0.1 1.7 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1 0.6 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 0.6 GO:0045350 interferon-beta biosynthetic process(GO:0045350) regulation of interferon-beta biosynthetic process(GO:0045357) positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.1 0.4 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.1 2.2 GO:0006270 DNA replication initiation(GO:0006270)
0.1 0.2 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.1 0.2 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.1 0.5 GO:0007090 obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.1 0.6 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.1 1.5 GO:0015701 bicarbonate transport(GO:0015701)
0.1 0.4 GO:0051290 protein heterotetramerization(GO:0051290)
0.1 0.3 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.1 0.8 GO:1901798 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.1 0.1 GO:0045992 negative regulation of embryonic development(GO:0045992)
0.1 0.2 GO:0060677 ureteric bud elongation(GO:0060677) renal vesicle formation(GO:0072033)
0.1 0.9 GO:0006596 polyamine biosynthetic process(GO:0006596)
0.1 0.2 GO:0031297 replication fork processing(GO:0031297)
0.1 0.4 GO:0032508 DNA duplex unwinding(GO:0032508)
0.1 0.2 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.1 1.7 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.1 1.2 GO:0000303 response to superoxide(GO:0000303)
0.1 0.1 GO:0006740 NADPH regeneration(GO:0006740)
0.1 0.2 GO:0031054 miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587) pre-miRNA processing(GO:0031054)
0.1 0.2 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272) embryonic skeletal joint development(GO:0072498)
0.1 0.1 GO:0032693 negative regulation of interleukin-10 production(GO:0032693)
0.1 0.3 GO:0032203 telomere formation via telomerase(GO:0032203)
0.1 0.6 GO:0048070 regulation of developmental pigmentation(GO:0048070)
0.1 0.2 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.1 0.2 GO:0010157 response to chlorate(GO:0010157)
0.1 0.2 GO:0060259 regulation of feeding behavior(GO:0060259)
0.1 0.2 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.1 0.2 GO:0042262 DNA protection(GO:0042262)
0.1 0.5 GO:0015074 DNA integration(GO:0015074)
0.0 0.5 GO:0051608 histamine transport(GO:0051608)
0.0 0.2 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.2 GO:0033622 integrin activation(GO:0033622) regulation of integrin activation(GO:0033623) positive regulation of integrin activation(GO:0033625)
0.0 0.8 GO:0006098 pentose-phosphate shunt(GO:0006098) glyceraldehyde-3-phosphate metabolic process(GO:0019682)
0.0 0.0 GO:0035106 operant conditioning(GO:0035106)
0.0 0.1 GO:0021898 commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.0 0.4 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.1 GO:0006167 AMP biosynthetic process(GO:0006167)
0.0 0.2 GO:0000089 mitotic metaphase(GO:0000089)
0.0 0.6 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.0 0.2 GO:0045048 protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0 0.4 GO:0006983 ER overload response(GO:0006983)
0.0 0.2 GO:1902414 protein localization to adherens junction(GO:0071896) protein localization to cell junction(GO:1902414)
0.0 0.2 GO:0072106 regulation of ureteric bud formation(GO:0072106) positive regulation of ureteric bud formation(GO:0072107)
0.0 0.4 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.2 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.2 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.0 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0 0.7 GO:0006000 fructose metabolic process(GO:0006000)
0.0 0.1 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.7 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.0 0.2 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.0 0.1 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.1 GO:0030163 protein catabolic process(GO:0030163)
0.0 0.2 GO:0000491 small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0 0.6 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.0 GO:0016246 RNA interference(GO:0016246)
0.0 0.5 GO:0009086 methionine biosynthetic process(GO:0009086)
0.0 0.2 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.1 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.3 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.3 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.6 GO:0006400 tRNA modification(GO:0006400)
0.0 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.3 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.1 GO:0002125 maternal aggressive behavior(GO:0002125)
0.0 0.1 GO:0000239 pachytene(GO:0000239)
0.0 0.2 GO:0050685 positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0 0.3 GO:0016180 snRNA processing(GO:0016180)
0.0 0.5 GO:0031648 protein destabilization(GO:0031648)
0.0 0.2 GO:0023041 neuronal signal transduction(GO:0023041)
0.0 0.3 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.0 0.2 GO:0051383 kinetochore assembly(GO:0051382) kinetochore organization(GO:0051383)
0.0 0.1 GO:0061101 neuroendocrine cell differentiation(GO:0061101)
0.0 0.2 GO:0045056 transcytosis(GO:0045056)
0.0 0.4 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.4 GO:0000090 mitotic anaphase(GO:0000090)
0.0 0.4 GO:0002021 response to dietary excess(GO:0002021)
0.0 0.2 GO:0002360 T cell lineage commitment(GO:0002360)
0.0 0.1 GO:0051503 adenine nucleotide transport(GO:0051503)
0.0 0.1 GO:0007207 phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0 0.9 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 0.1 GO:0030952 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0 0.3 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.3 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.1 GO:0014040 regulation of Schwann cell differentiation(GO:0014038) positive regulation of Schwann cell differentiation(GO:0014040)
0.0 0.2 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.2 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.0 0.2 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082)
0.0 1.2 GO:0048146 positive regulation of fibroblast proliferation(GO:0048146)
0.0 0.3 GO:0002566 somatic diversification of immune receptors via somatic mutation(GO:0002566) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.4 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.3 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.6 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.2 GO:0001866 NK T cell proliferation(GO:0001866)
0.0 0.6 GO:1904407 positive regulation of nitric oxide biosynthetic process(GO:0045429) positive regulation of reactive oxygen species biosynthetic process(GO:1903428) positive regulation of nitric oxide metabolic process(GO:1904407)
0.0 0.4 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.1 GO:1903825 organic acid transmembrane transport(GO:1903825) carboxylic acid transmembrane transport(GO:1905039)
0.0 0.4 GO:0006386 transcription elongation from RNA polymerase III promoter(GO:0006385) termination of RNA polymerase III transcription(GO:0006386)
0.0 0.1 GO:0016074 snoRNA metabolic process(GO:0016074)
0.0 0.1 GO:0022417 protein maturation by protein folding(GO:0022417)
0.0 0.2 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.0 0.2 GO:0006561 proline biosynthetic process(GO:0006561)
0.0 1.1 GO:0048477 oogenesis(GO:0048477)
0.0 0.1 GO:0018106 peptidyl-histidine phosphorylation(GO:0018106)
0.0 0.9 GO:0043487 regulation of RNA stability(GO:0043487)
0.0 1.2 GO:0060041 retina development in camera-type eye(GO:0060041)
0.0 0.4 GO:0060760 positive regulation of response to cytokine stimulus(GO:0060760)
0.0 0.2 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.2 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0 0.1 GO:0000394 RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394) tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.1 GO:0003077 obsolete negative regulation of diuresis(GO:0003077)
0.0 0.1 GO:0030913 paranodal junction assembly(GO:0030913)
0.0 0.0 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.0 GO:0090009 primitive streak formation(GO:0090009)
0.0 2.3 GO:0008016 regulation of heart contraction(GO:0008016)
0.0 0.1 GO:0002575 basophil chemotaxis(GO:0002575)
0.0 0.1 GO:0060689 cell differentiation involved in salivary gland development(GO:0060689)
0.0 0.2 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.0 0.3 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.2 GO:0060992 response to fungicide(GO:0060992)
0.0 2.5 GO:0042254 ribosome biogenesis(GO:0042254)
0.0 0.0 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 0.1 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.1 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0 0.1 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 0.2 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.1 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.0 0.2 GO:0050688 regulation of response to biotic stimulus(GO:0002831) regulation of defense response to virus(GO:0050688) regulation of defense response to virus by virus(GO:0050690)
0.0 0.1 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.2 GO:0051103 DNA ligation involved in DNA repair(GO:0051103)
0.0 0.1 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.0 0.2 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.2 GO:0046037 GMP metabolic process(GO:0046037)
0.0 0.1 GO:0002378 immunoglobulin biosynthetic process(GO:0002378) protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.2 GO:0046902 regulation of mitochondrial membrane permeability(GO:0046902) regulation of membrane permeability(GO:0090559)
0.0 0.4 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.3 GO:0048246 macrophage chemotaxis(GO:0048246)
0.0 0.1 GO:0006325 chromatin organization(GO:0006325)
0.0 0.1 GO:0015840 urea transport(GO:0015840)
0.0 1.0 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.0 GO:0051582 positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.0 1.1 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.1 GO:0070245 positive regulation of T cell apoptotic process(GO:0070234) positive regulation of thymocyte apoptotic process(GO:0070245)
0.0 0.6 GO:0030866 cortical cytoskeleton organization(GO:0030865) cortical actin cytoskeleton organization(GO:0030866)
0.0 0.1 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0 0.1 GO:0009439 cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440)
0.0 0.2 GO:1901983 regulation of histone acetylation(GO:0035065) regulation of protein acetylation(GO:1901983) regulation of peptidyl-lysine acetylation(GO:2000756)
0.0 0.4 GO:0017144 drug metabolic process(GO:0017144)
0.0 0.1 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.7 GO:0070303 negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303)
0.0 0.3 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.0 0.2 GO:0001516 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.0 0.2 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.0 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.0 0.2 GO:0001502 cartilage condensation(GO:0001502) cell aggregation(GO:0098743)
0.0 0.0 GO:0070781 response to biotin(GO:0070781)
0.0 0.1 GO:0038179 neurotrophin signaling pathway(GO:0038179) neurotrophin TRK receptor signaling pathway(GO:0048011)
0.0 0.1 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.0 2.7 GO:0006470 protein dephosphorylation(GO:0006470)
0.0 0.2 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.2 GO:0030593 neutrophil chemotaxis(GO:0030593) neutrophil migration(GO:1990266)
0.0 0.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.3 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.1 GO:0060766 negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0 0.1 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.3 GO:0007059 chromosome segregation(GO:0007059)
0.0 1.2 GO:0030217 T cell differentiation(GO:0030217)
0.0 0.1 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.3 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.0 GO:0072053 renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054)
0.0 0.3 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.0 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 0.1 GO:0051597 response to methylmercury(GO:0051597)
0.0 0.1 GO:0032876 regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0 0.1 GO:0009067 aspartate family amino acid biosynthetic process(GO:0009067)
0.0 0.3 GO:0031055 DNA replication-independent nucleosome assembly(GO:0006336) chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) DNA replication-independent nucleosome organization(GO:0034724) CENP-A containing chromatin organization(GO:0061641)
0.0 0.0 GO:0006498 N-terminal protein lipidation(GO:0006498)
0.0 0.7 GO:0061025 membrane fusion(GO:0061025)
0.0 0.4 GO:0006023 aminoglycan biosynthetic process(GO:0006023)
0.0 0.1 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.1 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.0 GO:0002455 humoral immune response mediated by circulating immunoglobulin(GO:0002455)
0.0 0.2 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 0.1 GO:0043046 DNA methylation involved in embryo development(GO:0043045) DNA methylation involved in gamete generation(GO:0043046) changes to DNA methylation involved in embryo development(GO:1901538)
0.0 1.5 GO:0050658 nucleic acid transport(GO:0050657) RNA transport(GO:0050658) establishment of RNA localization(GO:0051236)
0.0 0.0 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.2 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.1 GO:0070555 response to interleukin-1(GO:0070555)
0.0 0.3 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.2 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.2 GO:0006970 response to osmotic stress(GO:0006970)
0.0 0.2 GO:0007020 microtubule nucleation(GO:0007020)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.4 1.1 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.4 3.9 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.3 1.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.2 1.9 GO:0005638 lamin filament(GO:0005638)
0.2 1.3 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.2 0.7 GO:0005641 nuclear envelope lumen(GO:0005641)
0.2 0.7 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 1.1 GO:0042575 DNA polymerase complex(GO:0042575)
0.1 1.9 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 1.1 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 0.5 GO:0035189 Rb-E2F complex(GO:0035189)
0.1 0.6 GO:0001740 Barr body(GO:0001740)
0.1 1.2 GO:0030061 mitochondrial crista(GO:0030061)
0.1 0.6 GO:0001741 XY body(GO:0001741)
0.1 1.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 4.3 GO:0042645 mitochondrial nucleoid(GO:0042645)
0.1 1.3 GO:0030122 AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.1 0.4 GO:0044295 axonal growth cone(GO:0044295)
0.1 0.7 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 1.1 GO:0031519 PcG protein complex(GO:0031519)
0.1 0.8 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 0.2 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.1 0.2 GO:0005686 U2 snRNP(GO:0005686)
0.1 1.0 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 0.6 GO:0005719 nuclear euchromatin(GO:0005719)
0.1 1.3 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 2.7 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 0.5 GO:0030897 HOPS complex(GO:0030897)
0.1 1.0 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 1.5 GO:0090568 NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)
0.1 0.5 GO:0070761 pre-snoRNP complex(GO:0070761)
0.1 0.3 GO:0000124 SAGA complex(GO:0000124)
0.1 0.3 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.1 0.2 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 0.2 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.1 1.2 GO:1990204 oxidoreductase complex(GO:1990204)
0.1 0.3 GO:0071817 MMXD complex(GO:0071817)
0.1 0.5 GO:0016272 prefoldin complex(GO:0016272)
0.1 0.1 GO:0032590 dendrite membrane(GO:0032590)
0.1 0.3 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 0.2 GO:0045257 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.3 GO:0031941 filamentous actin(GO:0031941)
0.0 0.1 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.0 0.3 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.2 GO:0031083 BLOC complex(GO:0031082) BLOC-1 complex(GO:0031083)
0.0 0.2 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.4 GO:0070822 Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822)
0.0 0.2 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.3 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.4 GO:0030894 replisome(GO:0030894) nuclear replisome(GO:0043601)
0.0 0.4 GO:0005678 obsolete chromatin assembly complex(GO:0005678)
0.0 0.7 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 1.2 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.2 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.1 GO:0001652 granular component(GO:0001652)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 0.6 GO:0019861 obsolete flagellum(GO:0019861)
0.0 0.9 GO:0019717 obsolete synaptosome(GO:0019717)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 0.4 GO:1903561 extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0 2.7 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.2 GO:0033177 proton-transporting two-sector ATPase complex, proton-transporting domain(GO:0033177)
0.0 0.2 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.7 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.2 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.1 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.1 GO:0070288 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.0 0.2 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.2 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 0.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 2.0 GO:0000790 nuclear chromatin(GO:0000790)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.0 GO:0042587 glycogen granule(GO:0042587)
0.0 0.3 GO:0097610 cell division site(GO:0032153) cleavage furrow(GO:0032154) cell division site part(GO:0032155) cell surface furrow(GO:0097610)
0.0 0.2 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.1 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.3 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 7.7 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 2.0 GO:0005643 nuclear pore(GO:0005643)
0.0 0.2 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 0.6 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.2 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742) outer mitochondrial membrane protein complex(GO:0098799)
0.0 0.1 GO:0030904 retromer complex(GO:0030904)
0.0 0.1 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.5 GO:0001772 immunological synapse(GO:0001772)
0.0 0.6 GO:0031526 brush border membrane(GO:0031526)
0.0 0.1 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.1 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.3 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.4 GO:0030135 coated vesicle(GO:0030135)
0.0 0.2 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 1.7 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 2.0 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.7 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.1 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 1.8 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.2 GO:0005858 axonemal dynein complex(GO:0005858) axoneme part(GO:0044447)
0.0 0.4 GO:0045202 synapse(GO:0045202)
0.0 0.2 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.0 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.3 GO:0016592 mediator complex(GO:0016592)
0.0 0.1 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.1 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.1 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.7 GO:0032587 ruffle membrane(GO:0032587)
0.0 1.1 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.2 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.1 GO:0034399 nuclear periphery(GO:0034399)
0.0 0.2 GO:0044431 Golgi apparatus part(GO:0044431)
0.0 0.0 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.0 GO:0016600 flotillin complex(GO:0016600)
0.0 0.4 GO:0000776 kinetochore(GO:0000776)
0.0 0.1 GO:0031143 pseudopodium(GO:0031143)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.9 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.7 2.2 GO:0070361 mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
0.4 3.1 GO:0008732 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.4 1.3 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.4 1.6 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.4 1.4 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.4 1.1 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.3 1.0 GO:0008263 pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
0.3 1.3 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.2 1.0 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.2 0.9 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.2 1.8 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.2 0.7 GO:0003896 DNA primase activity(GO:0003896)
0.2 0.8 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.2 1.0 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.2 1.1 GO:0019238 cyclohydrolase activity(GO:0019238)
0.2 0.5 GO:0005329 dopamine transmembrane transporter activity(GO:0005329)
0.2 1.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.2 2.0 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.2 1.1 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.2 0.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.2 0.5 GO:0043426 histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648) MRF binding(GO:0043426)
0.2 1.2 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.1 0.4 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.1 0.4 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
0.1 1.0 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 1.5 GO:0061659 ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.1 1.0 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 1.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 0.6 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.1 1.8 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.1 2.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 0.7 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 1.5 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 0.6 GO:0030911 TPR domain binding(GO:0030911)
0.1 0.3 GO:0005224 ATP-binding and phosphorylation-dependent chloride channel activity(GO:0005224) channel-conductance-controlling ATPase activity(GO:0005260)
0.1 0.5 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.1 0.4 GO:0001849 complement component C1q binding(GO:0001849)
0.1 0.8 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.1 0.5 GO:0035184 histone threonine kinase activity(GO:0035184)
0.1 0.6 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.1 0.3 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.1 0.5 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.1 0.3 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.1 0.4 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.1 0.4 GO:0003951 NAD+ kinase activity(GO:0003951)
0.1 0.2 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.1 1.6 GO:0030332 cyclin binding(GO:0030332)
0.1 0.3 GO:0004122 cystathionine beta-synthase activity(GO:0004122)
0.1 0.6 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 1.9 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 0.4 GO:0004766 spermidine synthase activity(GO:0004766)
0.1 0.4 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.1 0.2 GO:0017130 poly(C) RNA binding(GO:0017130)
0.1 0.5 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 1.4 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.1 0.2 GO:0015141 thiosulfate transmembrane transporter activity(GO:0015117) succinate transmembrane transporter activity(GO:0015141)
0.1 1.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.7 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 0.4 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 2.0 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.1 0.4 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.1 0.3 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.1 0.7 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 0.2 GO:0030611 arsenate reductase activity(GO:0030611)
0.1 1.0 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 0.8 GO:0004707 MAP kinase activity(GO:0004707)
0.1 0.4 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 0.7 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.1 0.1 GO:0015216 adenine nucleotide transmembrane transporter activity(GO:0000295) purine nucleotide transmembrane transporter activity(GO:0015216)
0.1 0.4 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 1.5 GO:0019213 deacetylase activity(GO:0019213)
0.1 0.5 GO:0070087 chromo shadow domain binding(GO:0070087)
0.1 0.7 GO:0016918 retinal binding(GO:0016918)
0.1 0.8 GO:0005521 lamin binding(GO:0005521)
0.1 0.8 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.1 0.2 GO:0015925 galactosidase activity(GO:0015925)
0.1 0.1 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.1 2.0 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.1 0.2 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.1 0.3 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.1 0.5 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 0.2 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.2 GO:0048039 succinate dehydrogenase activity(GO:0000104) ubiquinone binding(GO:0048039)
0.0 0.7 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.9 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.1 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.0 0.6 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0 0.4 GO:0004835 tubulin-tyrosine ligase activity(GO:0004835)
0.0 0.8 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.0 GO:0002039 p53 binding(GO:0002039)
0.0 0.4 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 1.0 GO:0004659 prenyltransferase activity(GO:0004659)
0.0 0.4 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.0 0.1 GO:0043559 insulin binding(GO:0043559)
0.0 0.2 GO:0016997 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0 0.8 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0003863 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.0 0.2 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.1 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.2 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.1 GO:0000156 phosphorelay response regulator activity(GO:0000156)
0.0 0.1 GO:0043140 bubble DNA binding(GO:0000405) ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.0 0.1 GO:0008489 UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
0.0 0.3 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.4 GO:0030515 snoRNA binding(GO:0030515)
0.0 1.2 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 1.2 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.0 0.3 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 1.9 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.4 GO:0045502 dynein binding(GO:0045502)
0.0 1.4 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 1.9 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.3 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.0 0.2 GO:0008907 integrase activity(GO:0008907)
0.0 0.1 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.8 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.8 GO:0005109 frizzled binding(GO:0005109)
0.0 0.3 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.2 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 0.1 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.0 0.3 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.2 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.5 GO:0070061 fructose binding(GO:0070061)
0.0 1.5 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 1.0 GO:0050661 NADP binding(GO:0050661)
0.0 0.2 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.1 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.1 GO:0004960 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.0 0.4 GO:0000049 tRNA binding(GO:0000049)
0.0 0.2 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.5 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 1.0 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.1 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.2 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.1 GO:0055103 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.2 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.4 GO:0051920 peroxiredoxin activity(GO:0051920)
0.0 2.2 GO:0050660 flavin adenine dinucleotide binding(GO:0050660)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.2 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.2 GO:0042978 ornithine decarboxylase inhibitor activity(GO:0008073) ornithine decarboxylase activator activity(GO:0042978)
0.0 0.1 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.2 GO:0004340 glucokinase activity(GO:0004340)
0.0 0.2 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.7 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0016531 copper chaperone activity(GO:0016531)
0.0 0.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.1 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.1 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 0.7 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.2 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.4 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.1 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 2.7 GO:0015631 tubulin binding(GO:0015631)
0.0 0.3 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.1 GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0 0.8 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.1 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 3.0 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.4 GO:0005522 profilin binding(GO:0005522)
0.0 1.0 GO:0016875 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 1.0 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.6 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.1 GO:0016784 3-mercaptopyruvate sulfurtransferase activity(GO:0016784)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.0 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.1 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.2 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.3 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.7 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.1 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.1 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.8 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.1 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.3 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.2 GO:0031701 angiotensin receptor binding(GO:0031701)
0.0 0.1 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.0 GO:0003706 obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.2 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.1 GO:0003990 acetylcholinesterase activity(GO:0003990) laminin-1 binding(GO:0043237)
0.0 0.2 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 1.0 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.0 0.1 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.0 0.1 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
0.0 0.7 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.1 GO:0015926 glucosidase activity(GO:0015926)
0.0 0.3 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 1.3 GO:0016566 obsolete specific transcriptional repressor activity(GO:0016566)
0.0 0.0 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0004518 nuclease activity(GO:0004518)
0.0 0.2 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.3 GO:0001948 glycoprotein binding(GO:0001948)
0.0 0.0 GO:0031493 nucleosomal histone binding(GO:0031493) SAM domain binding(GO:0032093)
0.0 0.2 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.4 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.3 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 0.1 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.2 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.2 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0 0.1 GO:0019103 pyrimidine nucleotide binding(GO:0019103)
0.0 0.2 GO:0015464 acetylcholine receptor activity(GO:0015464)
0.0 0.2 GO:0051117 ATPase binding(GO:0051117)
0.0 0.3 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.1 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 3.3 GO:0005096 GTPase activator activity(GO:0005096)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 1.6 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.0 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.4 ST_STAT3_PATHWAY STAT3 Pathway
0.0 0.6 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.1 SA_TRKA_RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.2 ST_GRANULE_CELL_SURVIVAL_PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 1.0 ST_T_CELL_SIGNAL_TRANSDUCTION T Cell Signal Transduction
0.0 0.5 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.3 SIG_CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.2 ST_B_CELL_ANTIGEN_RECEPTOR B Cell Antigen Receptor