Motif ID: MNT_HEY1_HEY2
Z-value: 1.208
Transcription factors associated with MNT_HEY1_HEY2:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
HEY1 | ENSG00000164683.12 | HEY1 |
HEY2 | ENSG00000135547.4 | HEY2 |
MNT | ENSG00000070444.10 | MNT |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.3 | 3.9 | GO:1990170 | detoxification of cadmium ion(GO:0071585) stress response to cadmium ion(GO:1990170) |
0.7 | 2.2 | GO:0070407 | oxidation-dependent protein catabolic process(GO:0070407) |
0.6 | 1.9 | GO:0046449 | allantoin metabolic process(GO:0000255) mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338) |
0.6 | 1.7 | GO:0006273 | lagging strand elongation(GO:0006273) |
0.4 | 3.1 | GO:0019264 | glycine biosynthetic process from serine(GO:0019264) |
0.4 | 1.5 | GO:0000212 | meiotic spindle organization(GO:0000212) |
0.4 | 1.4 | GO:0043490 | malate-aspartate shuttle(GO:0043490) |
0.4 | 1.1 | GO:0070734 | histone H3-K27 methylation(GO:0070734) |
0.3 | 1.0 | GO:0019858 | cytosine metabolic process(GO:0019858) |
0.3 | 1.2 | GO:0010944 | negative regulation of transcription by competitive promoter binding(GO:0010944) |
0.3 | 1.1 | GO:0000463 | maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470) |
0.3 | 0.8 | GO:0014022 | neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007) |
0.3 | 1.0 | GO:0051534 | negative regulation of NFAT protein import into nucleus(GO:0051534) |
0.3 | 2.0 | GO:0006188 | IMP biosynthetic process(GO:0006188) IMP metabolic process(GO:0046040) |
0.3 | 1.0 | GO:0048642 | negative regulation of skeletal muscle tissue development(GO:0048642) |
0.2 | 2.1 | GO:0050884 | neuromuscular process controlling posture(GO:0050884) |
0.2 | 1.8 | GO:0015862 | uridine transport(GO:0015862) |
0.2 | 0.8 | GO:0019348 | polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348) |
0.2 | 1.5 | GO:0050847 | progesterone receptor signaling pathway(GO:0050847) |
0.2 | 1.9 | GO:0021800 | cerebral cortex tangential migration(GO:0021800) |
0.2 | 1.0 | GO:0006344 | maintenance of chromatin silencing(GO:0006344) |
0.2 | 2.7 | GO:0031115 | negative regulation of microtubule polymerization(GO:0031115) |
0.2 | 0.5 | GO:0090206 | negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206) |
0.2 | 0.5 | GO:0043371 | negative regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043371) negative regulation of T-helper cell differentiation(GO:0045623) negative regulation of CD4-positive, alpha-beta T cell activation(GO:2000515) |
0.2 | 0.8 | GO:0010508 | positive regulation of autophagy(GO:0010508) |
0.2 | 0.7 | GO:0040016 | embryonic cleavage(GO:0040016) |
0.2 | 1.0 | GO:0006552 | leucine catabolic process(GO:0006552) |
0.2 | 1.0 | GO:0006999 | nuclear pore organization(GO:0006999) |
0.2 | 1.4 | GO:0018126 | protein hydroxylation(GO:0018126) |
0.2 | 0.5 | GO:0034720 | histone H3-K4 demethylation(GO:0034720) |
0.1 | 0.7 | GO:0008295 | spermidine biosynthetic process(GO:0008295) |
0.1 | 0.6 | GO:0000966 | RNA 5'-end processing(GO:0000966) |
0.1 | 0.4 | GO:0034755 | iron ion transmembrane transport(GO:0034755) |
0.1 | 0.4 | GO:0019242 | methylglyoxal biosynthetic process(GO:0019242) |
0.1 | 0.4 | GO:0061117 | negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of cardiac muscle tissue development(GO:0055026) negative regulation of cardiac muscle cell proliferation(GO:0060044) negative regulation of heart growth(GO:0061117) |
0.1 | 0.7 | GO:0070935 | 3'-UTR-mediated mRNA stabilization(GO:0070935) |
0.1 | 1.2 | GO:0006546 | glycine catabolic process(GO:0006546) |
0.1 | 0.5 | GO:0045199 | maintenance of epithelial cell apical/basal polarity(GO:0045199) |
0.1 | 0.4 | GO:0034626 | fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
0.1 | 0.5 | GO:0001575 | globoside metabolic process(GO:0001575) |
0.1 | 0.5 | GO:0009048 | dosage compensation by inactivation of X chromosome(GO:0009048) |
0.1 | 1.1 | GO:0032464 | positive regulation of protein homooligomerization(GO:0032464) |
0.1 | 0.3 | GO:0070544 | histone H3-K36 demethylation(GO:0070544) |
0.1 | 1.2 | GO:0000076 | DNA replication checkpoint(GO:0000076) |
0.1 | 0.9 | GO:0045008 | depyrimidination(GO:0045008) |
0.1 | 0.3 | GO:0090073 | positive regulation of protein homodimerization activity(GO:0090073) |
0.1 | 0.5 | GO:0035405 | histone-threonine phosphorylation(GO:0035405) |
0.1 | 0.3 | GO:0045618 | positive regulation of keratinocyte differentiation(GO:0045618) |
0.1 | 0.4 | GO:0006207 | 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856) |
0.1 | 0.7 | GO:0021903 | rostrocaudal neural tube patterning(GO:0021903) |
0.1 | 0.5 | GO:1901984 | negative regulation of histone acetylation(GO:0035067) negative regulation of protein acetylation(GO:1901984) negative regulation of peptidyl-lysine acetylation(GO:2000757) |
0.1 | 0.3 | GO:0043418 | cysteine biosynthetic process from serine(GO:0006535) homoserine metabolic process(GO:0009092) cysteine biosynthetic process via cystathionine(GO:0019343) transsulfuration(GO:0019346) homocysteine catabolic process(GO:0043418) |
0.1 | 0.4 | GO:0034723 | DNA replication-dependent nucleosome organization(GO:0034723) |
0.1 | 0.6 | GO:0042483 | negative regulation of odontogenesis(GO:0042483) |
0.1 | 0.6 | GO:0009113 | purine nucleobase biosynthetic process(GO:0009113) |
0.1 | 0.7 | GO:0045039 | protein import into mitochondrial inner membrane(GO:0045039) |
0.1 | 1.3 | GO:0048268 | clathrin coat assembly(GO:0048268) |
0.1 | 0.3 | GO:0042744 | hydrogen peroxide metabolic process(GO:0042743) hydrogen peroxide catabolic process(GO:0042744) |
0.1 | 0.9 | GO:0042362 | fat-soluble vitamin biosynthetic process(GO:0042362) |
0.1 | 0.9 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
0.1 | 0.3 | GO:0047484 | regulation of response to osmotic stress(GO:0047484) |
0.1 | 0.3 | GO:0006384 | transcription initiation from RNA polymerase III promoter(GO:0006384) |
0.1 | 2.4 | GO:0036503 | ER-associated ubiquitin-dependent protein catabolic process(GO:0030433) ERAD pathway(GO:0036503) |
0.1 | 2.5 | GO:0003333 | amino acid transmembrane transport(GO:0003333) |
0.1 | 0.4 | GO:0060397 | JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397) |
0.1 | 0.2 | GO:0070445 | Fc receptor mediated stimulatory signaling pathway(GO:0002431) regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369) oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445) positive regulation of oligodendrocyte progenitor proliferation(GO:0070447) |
0.1 | 0.5 | GO:0045945 | positive regulation of transcription from RNA polymerase III promoter(GO:0045945) |
0.1 | 0.8 | GO:0042535 | positive regulation of tumor necrosis factor biosynthetic process(GO:0042535) |
0.1 | 1.7 | GO:0071577 | zinc II ion transmembrane transport(GO:0071577) |
0.1 | 0.2 | GO:0051083 | 'de novo' cotranslational protein folding(GO:0051083) |
0.1 | 2.2 | GO:0006099 | tricarboxylic acid cycle(GO:0006099) |
0.1 | 0.4 | GO:0006422 | aspartyl-tRNA aminoacylation(GO:0006422) |
0.1 | 0.6 | GO:0046174 | polyol catabolic process(GO:0046174) |
0.1 | 1.5 | GO:0009812 | flavonoid metabolic process(GO:0009812) |
0.1 | 0.2 | GO:0003289 | septum primum development(GO:0003284) atrial septum primum morphogenesis(GO:0003289) |
0.1 | 0.6 | GO:0030422 | production of siRNA involved in RNA interference(GO:0030422) |
0.1 | 0.2 | GO:0002082 | regulation of oxidative phosphorylation(GO:0002082) |
0.1 | 1.7 | GO:0000291 | nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928) |
0.1 | 0.6 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway(GO:0048387) |
0.1 | 0.6 | GO:0045350 | interferon-beta biosynthetic process(GO:0045350) regulation of interferon-beta biosynthetic process(GO:0045357) positive regulation of interferon-beta biosynthetic process(GO:0045359) |
0.1 | 0.4 | GO:0043985 | histone H4-R3 methylation(GO:0043985) |
0.1 | 2.2 | GO:0006270 | DNA replication initiation(GO:0006270) |
0.1 | 0.2 | GO:0046292 | formaldehyde metabolic process(GO:0046292) |
0.1 | 0.2 | GO:0021529 | spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780) |
0.1 | 0.5 | GO:0007090 | obsolete regulation of S phase of mitotic cell cycle(GO:0007090) |
0.1 | 0.6 | GO:0006359 | regulation of transcription from RNA polymerase III promoter(GO:0006359) |
0.1 | 1.5 | GO:0015701 | bicarbonate transport(GO:0015701) |
0.1 | 0.4 | GO:0051290 | protein heterotetramerization(GO:0051290) |
0.1 | 0.3 | GO:0045875 | negative regulation of sister chromatid cohesion(GO:0045875) |
0.1 | 0.8 | GO:1901798 | positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798) |
0.1 | 0.1 | GO:0045992 | negative regulation of embryonic development(GO:0045992) |
0.1 | 0.2 | GO:0060677 | ureteric bud elongation(GO:0060677) renal vesicle formation(GO:0072033) |
0.1 | 0.9 | GO:0006596 | polyamine biosynthetic process(GO:0006596) |
0.1 | 0.2 | GO:0031297 | replication fork processing(GO:0031297) |
0.1 | 0.4 | GO:0032508 | DNA duplex unwinding(GO:0032508) |
0.1 | 0.2 | GO:0018206 | peptidyl-methionine modification(GO:0018206) |
0.1 | 1.7 | GO:0015949 | nucleobase-containing small molecule interconversion(GO:0015949) |
0.1 | 1.2 | GO:0000303 | response to superoxide(GO:0000303) |
0.1 | 0.1 | GO:0006740 | NADPH regeneration(GO:0006740) |
0.1 | 0.2 | GO:0031054 | miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587) pre-miRNA processing(GO:0031054) |
0.1 | 0.2 | GO:0060272 | embryonic skeletal joint morphogenesis(GO:0060272) embryonic skeletal joint development(GO:0072498) |
0.1 | 0.1 | GO:0032693 | negative regulation of interleukin-10 production(GO:0032693) |
0.1 | 0.3 | GO:0032203 | telomere formation via telomerase(GO:0032203) |
0.1 | 0.6 | GO:0048070 | regulation of developmental pigmentation(GO:0048070) |
0.1 | 0.2 | GO:0006434 | seryl-tRNA aminoacylation(GO:0006434) |
0.1 | 0.2 | GO:0010157 | response to chlorate(GO:0010157) |
0.1 | 0.2 | GO:0060259 | regulation of feeding behavior(GO:0060259) |
0.1 | 0.2 | GO:0046477 | glycosylceramide catabolic process(GO:0046477) |
0.1 | 0.2 | GO:0042262 | DNA protection(GO:0042262) |
0.1 | 0.5 | GO:0015074 | DNA integration(GO:0015074) |
0.0 | 0.5 | GO:0051608 | histamine transport(GO:0051608) |
0.0 | 0.2 | GO:0060528 | secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528) |
0.0 | 0.2 | GO:0033622 | integrin activation(GO:0033622) regulation of integrin activation(GO:0033623) positive regulation of integrin activation(GO:0033625) |
0.0 | 0.8 | GO:0006098 | pentose-phosphate shunt(GO:0006098) glyceraldehyde-3-phosphate metabolic process(GO:0019682) |
0.0 | 0.0 | GO:0035106 | operant conditioning(GO:0035106) |
0.0 | 0.1 | GO:0021898 | commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898) |
0.0 | 0.4 | GO:0006072 | glycerol-3-phosphate metabolic process(GO:0006072) |
0.0 | 0.1 | GO:0006167 | AMP biosynthetic process(GO:0006167) |
0.0 | 0.2 | GO:0000089 | mitotic metaphase(GO:0000089) |
0.0 | 0.6 | GO:0032703 | negative regulation of interleukin-2 production(GO:0032703) |
0.0 | 0.2 | GO:0045048 | protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816) |
0.0 | 0.4 | GO:0006983 | ER overload response(GO:0006983) |
0.0 | 0.2 | GO:1902414 | protein localization to adherens junction(GO:0071896) protein localization to cell junction(GO:1902414) |
0.0 | 0.2 | GO:0072106 | regulation of ureteric bud formation(GO:0072106) positive regulation of ureteric bud formation(GO:0072107) |
0.0 | 0.4 | GO:0007217 | tachykinin receptor signaling pathway(GO:0007217) |
0.0 | 0.2 | GO:0019509 | L-methionine biosynthetic process from methylthioadenosine(GO:0019509) |
0.0 | 0.2 | GO:0031580 | membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580) |
0.0 | 0.0 | GO:0051771 | negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771) |
0.0 | 0.7 | GO:0006000 | fructose metabolic process(GO:0006000) |
0.0 | 0.1 | GO:0018095 | protein polyglutamylation(GO:0018095) |
0.0 | 0.7 | GO:0045668 | negative regulation of osteoblast differentiation(GO:0045668) |
0.0 | 0.2 | GO:0006287 | base-excision repair, gap-filling(GO:0006287) |
0.0 | 0.1 | GO:0032927 | positive regulation of activin receptor signaling pathway(GO:0032927) |
0.0 | 0.1 | GO:0030163 | protein catabolic process(GO:0030163) |
0.0 | 0.2 | GO:0000491 | small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492) |
0.0 | 0.6 | GO:0051131 | chaperone-mediated protein complex assembly(GO:0051131) |
0.0 | 0.0 | GO:0016246 | RNA interference(GO:0016246) |
0.0 | 0.5 | GO:0009086 | methionine biosynthetic process(GO:0009086) |
0.0 | 0.2 | GO:0032780 | negative regulation of ATPase activity(GO:0032780) |
0.0 | 0.1 | GO:0016080 | synaptic vesicle targeting(GO:0016080) |
0.0 | 0.3 | GO:0070327 | thyroid hormone transport(GO:0070327) |
0.0 | 0.3 | GO:0043457 | regulation of cellular respiration(GO:0043457) |
0.0 | 0.1 | GO:0006391 | transcription initiation from mitochondrial promoter(GO:0006391) |
0.0 | 0.6 | GO:0006400 | tRNA modification(GO:0006400) |
0.0 | 0.2 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
0.0 | 0.3 | GO:0006975 | DNA damage induced protein phosphorylation(GO:0006975) |
0.0 | 0.1 | GO:0002125 | maternal aggressive behavior(GO:0002125) |
0.0 | 0.1 | GO:0000239 | pachytene(GO:0000239) |
0.0 | 0.2 | GO:0050685 | positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313) |
0.0 | 0.3 | GO:0016180 | snRNA processing(GO:0016180) |
0.0 | 0.5 | GO:0031648 | protein destabilization(GO:0031648) |
0.0 | 0.2 | GO:0023041 | neuronal signal transduction(GO:0023041) |
0.0 | 0.3 | GO:0046835 | carbohydrate phosphorylation(GO:0046835) |
0.0 | 0.2 | GO:0051383 | kinetochore assembly(GO:0051382) kinetochore organization(GO:0051383) |
0.0 | 0.1 | GO:0061101 | neuroendocrine cell differentiation(GO:0061101) |
0.0 | 0.2 | GO:0045056 | transcytosis(GO:0045056) |
0.0 | 0.4 | GO:0001522 | pseudouridine synthesis(GO:0001522) |
0.0 | 0.4 | GO:0000090 | mitotic anaphase(GO:0000090) |
0.0 | 0.4 | GO:0002021 | response to dietary excess(GO:0002021) |
0.0 | 0.2 | GO:0002360 | T cell lineage commitment(GO:0002360) |
0.0 | 0.1 | GO:0051503 | adenine nucleotide transport(GO:0051503) |
0.0 | 0.1 | GO:0007207 | phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207) |
0.0 | 0.9 | GO:0071804 | cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805) |
0.0 | 0.1 | GO:0030952 | establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) establishment or maintenance of cytoskeleton polarity(GO:0030952) |
0.0 | 0.3 | GO:0022027 | interkinetic nuclear migration(GO:0022027) |
0.0 | 0.3 | GO:0006776 | vitamin A metabolic process(GO:0006776) |
0.0 | 0.1 | GO:0014040 | regulation of Schwann cell differentiation(GO:0014038) positive regulation of Schwann cell differentiation(GO:0014040) |
0.0 | 0.2 | GO:0006516 | glycoprotein catabolic process(GO:0006516) |
0.0 | 0.2 | GO:0010898 | positive regulation of triglyceride catabolic process(GO:0010898) |
0.0 | 0.2 | GO:0009082 | branched-chain amino acid biosynthetic process(GO:0009082) |
0.0 | 1.2 | GO:0048146 | positive regulation of fibroblast proliferation(GO:0048146) |
0.0 | 0.3 | GO:0002566 | somatic diversification of immune receptors via somatic mutation(GO:0002566) somatic hypermutation of immunoglobulin genes(GO:0016446) |
0.0 | 0.4 | GO:0006044 | N-acetylglucosamine metabolic process(GO:0006044) |
0.0 | 0.3 | GO:0035095 | behavioral response to nicotine(GO:0035095) |
0.0 | 0.6 | GO:0043968 | histone H2A acetylation(GO:0043968) |
0.0 | 0.2 | GO:0001866 | NK T cell proliferation(GO:0001866) |
0.0 | 0.6 | GO:1904407 | positive regulation of nitric oxide biosynthetic process(GO:0045429) positive regulation of reactive oxygen species biosynthetic process(GO:1903428) positive regulation of nitric oxide metabolic process(GO:1904407) |
0.0 | 0.4 | GO:0046854 | phosphatidylinositol phosphorylation(GO:0046854) |
0.0 | 0.1 | GO:1903825 | organic acid transmembrane transport(GO:1903825) carboxylic acid transmembrane transport(GO:1905039) |
0.0 | 0.4 | GO:0006386 | transcription elongation from RNA polymerase III promoter(GO:0006385) termination of RNA polymerase III transcription(GO:0006386) |
0.0 | 0.1 | GO:0016074 | snoRNA metabolic process(GO:0016074) |
0.0 | 0.1 | GO:0022417 | protein maturation by protein folding(GO:0022417) |
0.0 | 0.2 | GO:0033600 | negative regulation of mammary gland epithelial cell proliferation(GO:0033600) |
0.0 | 0.2 | GO:0006561 | proline biosynthetic process(GO:0006561) |
0.0 | 1.1 | GO:0048477 | oogenesis(GO:0048477) |
0.0 | 0.1 | GO:0018106 | peptidyl-histidine phosphorylation(GO:0018106) |
0.0 | 0.9 | GO:0043487 | regulation of RNA stability(GO:0043487) |
0.0 | 1.2 | GO:0060041 | retina development in camera-type eye(GO:0060041) |
0.0 | 0.4 | GO:0060760 | positive regulation of response to cytokine stimulus(GO:0060760) |
0.0 | 0.2 | GO:0000183 | chromatin silencing at rDNA(GO:0000183) |
0.0 | 0.2 | GO:0071378 | growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378) |
0.0 | 0.1 | GO:0000394 | RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394) tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388) |
0.0 | 0.1 | GO:0003077 | obsolete negative regulation of diuresis(GO:0003077) |
0.0 | 0.1 | GO:0030913 | paranodal junction assembly(GO:0030913) |
0.0 | 0.0 | GO:0034587 | piRNA metabolic process(GO:0034587) |
0.0 | 0.0 | GO:0090009 | primitive streak formation(GO:0090009) |
0.0 | 2.3 | GO:0008016 | regulation of heart contraction(GO:0008016) |
0.0 | 0.1 | GO:0002575 | basophil chemotaxis(GO:0002575) |
0.0 | 0.1 | GO:0060689 | cell differentiation involved in salivary gland development(GO:0060689) |
0.0 | 0.2 | GO:0006002 | fructose 6-phosphate metabolic process(GO:0006002) |
0.0 | 0.3 | GO:0006884 | cell volume homeostasis(GO:0006884) |
0.0 | 0.2 | GO:0060992 | response to fungicide(GO:0060992) |
0.0 | 2.5 | GO:0042254 | ribosome biogenesis(GO:0042254) |
0.0 | 0.0 | GO:0033147 | negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147) |
0.0 | 0.1 | GO:0043615 | astrocyte cell migration(GO:0043615) |
0.0 | 0.1 | GO:0008612 | peptidyl-lysine modification to peptidyl-hypusine(GO:0008612) |
0.0 | 0.1 | GO:0071044 | histone mRNA catabolic process(GO:0071044) |
0.0 | 0.2 | GO:0015937 | coenzyme A biosynthetic process(GO:0015937) |
0.0 | 0.1 | GO:0032878 | regulation of establishment or maintenance of cell polarity(GO:0032878) |
0.0 | 0.2 | GO:0050688 | regulation of response to biotic stimulus(GO:0002831) regulation of defense response to virus(GO:0050688) regulation of defense response to virus by virus(GO:0050690) |
0.0 | 0.1 | GO:0030263 | apoptotic chromosome condensation(GO:0030263) |
0.0 | 0.2 | GO:0051103 | DNA ligation involved in DNA repair(GO:0051103) |
0.0 | 0.1 | GO:0043117 | positive regulation of vascular permeability(GO:0043117) |
0.0 | 0.2 | GO:0007021 | tubulin complex assembly(GO:0007021) |
0.0 | 0.2 | GO:0046037 | GMP metabolic process(GO:0046037) |
0.0 | 0.1 | GO:0002378 | immunoglobulin biosynthetic process(GO:0002378) protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243) |
0.0 | 0.2 | GO:0046902 | regulation of mitochondrial membrane permeability(GO:0046902) regulation of membrane permeability(GO:0090559) |
0.0 | 0.4 | GO:0007597 | blood coagulation, intrinsic pathway(GO:0007597) |
0.0 | 0.3 | GO:0048246 | macrophage chemotaxis(GO:0048246) |
0.0 | 0.1 | GO:0006325 | chromatin organization(GO:0006325) |
0.0 | 0.1 | GO:0015840 | urea transport(GO:0015840) |
0.0 | 1.0 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
0.0 | 0.0 | GO:0051582 | positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944) |
0.0 | 1.1 | GO:0006369 | termination of RNA polymerase II transcription(GO:0006369) |
0.0 | 0.1 | GO:0018343 | protein farnesylation(GO:0018343) |
0.0 | 0.1 | GO:0070245 | positive regulation of T cell apoptotic process(GO:0070234) positive regulation of thymocyte apoptotic process(GO:0070245) |
0.0 | 0.6 | GO:0030866 | cortical cytoskeleton organization(GO:0030865) cortical actin cytoskeleton organization(GO:0030866) |
0.0 | 0.1 | GO:0002032 | desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032) |
0.0 | 0.1 | GO:0009439 | cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440) |
0.0 | 0.2 | GO:1901983 | regulation of histone acetylation(GO:0035065) regulation of protein acetylation(GO:1901983) regulation of peptidyl-lysine acetylation(GO:2000756) |
0.0 | 0.4 | GO:0017144 | drug metabolic process(GO:0017144) |
0.0 | 0.1 | GO:0035024 | negative regulation of Rho protein signal transduction(GO:0035024) |
0.0 | 0.7 | GO:0070303 | negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303) |
0.0 | 0.3 | GO:0050885 | neuromuscular process controlling balance(GO:0050885) |
0.0 | 0.2 | GO:0001516 | prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457) |
0.0 | 0.2 | GO:0000722 | telomere maintenance via recombination(GO:0000722) |
0.0 | 0.0 | GO:0016476 | regulation of embryonic cell shape(GO:0016476) |
0.0 | 0.2 | GO:0001502 | cartilage condensation(GO:0001502) cell aggregation(GO:0098743) |
0.0 | 0.0 | GO:0070781 | response to biotin(GO:0070781) |
0.0 | 0.1 | GO:0038179 | neurotrophin signaling pathway(GO:0038179) neurotrophin TRK receptor signaling pathway(GO:0048011) |
0.0 | 0.1 | GO:0006537 | glutamate biosynthetic process(GO:0006537) |
0.0 | 2.7 | GO:0006470 | protein dephosphorylation(GO:0006470) |
0.0 | 0.2 | GO:0006198 | cAMP catabolic process(GO:0006198) |
0.0 | 0.2 | GO:0030593 | neutrophil chemotaxis(GO:0030593) neutrophil migration(GO:1990266) |
0.0 | 0.1 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
0.0 | 0.3 | GO:0051865 | protein autoubiquitination(GO:0051865) |
0.0 | 0.1 | GO:0060766 | negative regulation of androgen receptor signaling pathway(GO:0060766) |
0.0 | 0.1 | GO:0001880 | Mullerian duct regression(GO:0001880) |
0.0 | 0.3 | GO:0007059 | chromosome segregation(GO:0007059) |
0.0 | 1.2 | GO:0030217 | T cell differentiation(GO:0030217) |
0.0 | 0.1 | GO:0032836 | glomerular basement membrane development(GO:0032836) |
0.0 | 0.3 | GO:0016925 | protein sumoylation(GO:0016925) |
0.0 | 0.0 | GO:0072053 | renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054) |
0.0 | 0.3 | GO:0016578 | histone deubiquitination(GO:0016578) |
0.0 | 0.0 | GO:0014067 | negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067) |
0.0 | 0.1 | GO:0051597 | response to methylmercury(GO:0051597) |
0.0 | 0.1 | GO:0032876 | regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023) |
0.0 | 0.1 | GO:0009067 | aspartate family amino acid biosynthetic process(GO:0009067) |
0.0 | 0.3 | GO:0031055 | DNA replication-independent nucleosome assembly(GO:0006336) chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) DNA replication-independent nucleosome organization(GO:0034724) CENP-A containing chromatin organization(GO:0061641) |
0.0 | 0.0 | GO:0006498 | N-terminal protein lipidation(GO:0006498) |
0.0 | 0.7 | GO:0061025 | membrane fusion(GO:0061025) |
0.0 | 0.4 | GO:0006023 | aminoglycan biosynthetic process(GO:0006023) |
0.0 | 0.1 | GO:0006474 | N-terminal protein amino acid acetylation(GO:0006474) |
0.0 | 0.1 | GO:0033962 | cytoplasmic mRNA processing body assembly(GO:0033962) |
0.0 | 0.0 | GO:0002455 | humoral immune response mediated by circulating immunoglobulin(GO:0002455) |
0.0 | 0.2 | GO:0006613 | cotranslational protein targeting to membrane(GO:0006613) |
0.0 | 0.1 | GO:0043046 | DNA methylation involved in embryo development(GO:0043045) DNA methylation involved in gamete generation(GO:0043046) changes to DNA methylation involved in embryo development(GO:1901538) |
0.0 | 1.5 | GO:0050658 | nucleic acid transport(GO:0050657) RNA transport(GO:0050658) establishment of RNA localization(GO:0051236) |
0.0 | 0.0 | GO:0016322 | neuron remodeling(GO:0016322) |
0.0 | 0.2 | GO:0050832 | defense response to fungus(GO:0050832) |
0.0 | 0.1 | GO:0070555 | response to interleukin-1(GO:0070555) |
0.0 | 0.3 | GO:0042147 | retrograde transport, endosome to Golgi(GO:0042147) |
0.0 | 0.2 | GO:0006383 | transcription from RNA polymerase III promoter(GO:0006383) |
0.0 | 0.2 | GO:0006970 | response to osmotic stress(GO:0006970) |
0.0 | 0.2 | GO:0007020 | microtubule nucleation(GO:0007020) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 1.8 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
0.4 | 1.1 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
0.4 | 3.9 | GO:0043190 | ATP-binding cassette (ABC) transporter complex(GO:0043190) |
0.3 | 1.2 | GO:0030688 | preribosome, small subunit precursor(GO:0030688) |
0.2 | 1.9 | GO:0005638 | lamin filament(GO:0005638) |
0.2 | 1.3 | GO:0005658 | alpha DNA polymerase:primase complex(GO:0005658) |
0.2 | 0.7 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
0.2 | 0.7 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
0.1 | 1.1 | GO:0042575 | DNA polymerase complex(GO:0042575) |
0.1 | 1.9 | GO:0000808 | origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664) |
0.1 | 1.1 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
0.1 | 0.5 | GO:0035189 | Rb-E2F complex(GO:0035189) |
0.1 | 0.6 | GO:0001740 | Barr body(GO:0001740) |
0.1 | 1.2 | GO:0030061 | mitochondrial crista(GO:0030061) |
0.1 | 0.6 | GO:0001741 | XY body(GO:0001741) |
0.1 | 1.4 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
0.1 | 4.3 | GO:0042645 | mitochondrial nucleoid(GO:0042645) |
0.1 | 1.3 | GO:0030122 | AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128) |
0.1 | 0.4 | GO:0044295 | axonal growth cone(GO:0044295) |
0.1 | 0.7 | GO:0042719 | mitochondrial intermembrane space protein transporter complex(GO:0042719) |
0.1 | 1.1 | GO:0031519 | PcG protein complex(GO:0031519) |
0.1 | 0.8 | GO:0014731 | spectrin-associated cytoskeleton(GO:0014731) |
0.1 | 0.2 | GO:0030981 | cortical microtubule cytoskeleton(GO:0030981) |
0.1 | 0.2 | GO:0005686 | U2 snRNP(GO:0005686) |
0.1 | 1.0 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
0.1 | 0.6 | GO:0005719 | nuclear euchromatin(GO:0005719) |
0.1 | 1.3 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
0.1 | 2.7 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
0.1 | 0.5 | GO:0030897 | HOPS complex(GO:0030897) |
0.1 | 1.0 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
0.1 | 1.5 | GO:0090568 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568) |
0.1 | 0.5 | GO:0070761 | pre-snoRNP complex(GO:0070761) |
0.1 | 0.3 | GO:0000124 | SAGA complex(GO:0000124) |
0.1 | 0.3 | GO:0031205 | endoplasmic reticulum Sec complex(GO:0031205) |
0.1 | 0.2 | GO:0032591 | dendritic spine membrane(GO:0032591) |
0.1 | 0.2 | GO:0034750 | Scrib-APC-beta-catenin complex(GO:0034750) |
0.1 | 1.2 | GO:1990204 | oxidoreductase complex(GO:1990204) |
0.1 | 0.3 | GO:0071817 | MMXD complex(GO:0071817) |
0.1 | 0.5 | GO:0016272 | prefoldin complex(GO:0016272) |
0.1 | 0.1 | GO:0032590 | dendrite membrane(GO:0032590) |
0.1 | 0.3 | GO:0009331 | glycerol-3-phosphate dehydrogenase complex(GO:0009331) |
0.1 | 0.2 | GO:0045257 | mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283) |
0.0 | 0.2 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
0.0 | 0.3 | GO:0031941 | filamentous actin(GO:0031941) |
0.0 | 0.1 | GO:0031074 | nucleocytoplasmic shuttling complex(GO:0031074) |
0.0 | 0.3 | GO:0000127 | transcription factor TFIIIC complex(GO:0000127) |
0.0 | 0.2 | GO:0031083 | BLOC complex(GO:0031082) BLOC-1 complex(GO:0031083) |
0.0 | 0.2 | GO:0071818 | BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379) |
0.0 | 0.4 | GO:0070822 | Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822) |
0.0 | 0.2 | GO:0030121 | AP-1 adaptor complex(GO:0030121) |
0.0 | 0.3 | GO:0046581 | intercellular canaliculus(GO:0046581) |
0.0 | 0.4 | GO:0030894 | replisome(GO:0030894) nuclear replisome(GO:0043601) |
0.0 | 0.4 | GO:0005678 | obsolete chromatin assembly complex(GO:0005678) |
0.0 | 0.7 | GO:0005763 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
0.0 | 1.2 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
0.0 | 0.2 | GO:0032133 | chromosome passenger complex(GO:0032133) |
0.0 | 0.2 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
0.0 | 0.1 | GO:0001652 | granular component(GO:0001652) |
0.0 | 0.1 | GO:0005947 | mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) |
0.0 | 0.2 | GO:0045179 | apical cortex(GO:0045179) |
0.0 | 0.6 | GO:0019861 | obsolete flagellum(GO:0019861) |
0.0 | 0.9 | GO:0019717 | obsolete synaptosome(GO:0019717) |
0.0 | 0.3 | GO:0032039 | integrator complex(GO:0032039) |
0.0 | 0.4 | GO:1903561 | extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561) |
0.0 | 2.7 | GO:0016363 | nuclear matrix(GO:0016363) |
0.0 | 0.2 | GO:0033177 | proton-transporting two-sector ATPase complex, proton-transporting domain(GO:0033177) |
0.0 | 0.2 | GO:0030130 | clathrin coat of trans-Golgi network vesicle(GO:0030130) |
0.0 | 0.7 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
0.0 | 0.2 | GO:0033179 | proton-transporting V-type ATPase, V0 domain(GO:0033179) |
0.0 | 0.1 | GO:0030119 | AP-type membrane coat adaptor complex(GO:0030119) |
0.0 | 0.1 | GO:0070288 | intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288) |
0.0 | 0.2 | GO:0005945 | 6-phosphofructokinase complex(GO:0005945) |
0.0 | 0.2 | GO:0034518 | mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518) |
0.0 | 0.3 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
0.0 | 2.0 | GO:0000790 | nuclear chromatin(GO:0000790) |
0.0 | 0.1 | GO:0000214 | tRNA-intron endonuclease complex(GO:0000214) |
0.0 | 0.0 | GO:0042587 | glycogen granule(GO:0042587) |
0.0 | 0.3 | GO:0097610 | cell division site(GO:0032153) cleavage furrow(GO:0032154) cell division site part(GO:0032155) cell surface furrow(GO:0097610) |
0.0 | 0.2 | GO:0043202 | lysosomal lumen(GO:0043202) |
0.0 | 0.1 | GO:0031594 | neuromuscular junction(GO:0031594) |
0.0 | 0.3 | GO:0031254 | uropod(GO:0001931) cell trailing edge(GO:0031254) |
0.0 | 0.3 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
0.0 | 7.7 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
0.0 | 2.0 | GO:0005643 | nuclear pore(GO:0005643) |
0.0 | 0.2 | GO:0000178 | exosome (RNase complex)(GO:0000178) |
0.0 | 0.6 | GO:0012507 | ER to Golgi transport vesicle membrane(GO:0012507) |
0.0 | 0.2 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
0.0 | 0.1 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) outer mitochondrial membrane protein complex(GO:0098799) |
0.0 | 0.1 | GO:0030904 | retromer complex(GO:0030904) |
0.0 | 0.1 | GO:0031527 | filopodium membrane(GO:0031527) |
0.0 | 0.5 | GO:0001772 | immunological synapse(GO:0001772) |
0.0 | 0.6 | GO:0031526 | brush border membrane(GO:0031526) |
0.0 | 0.1 | GO:0005677 | chromatin silencing complex(GO:0005677) |
0.0 | 0.1 | GO:0005663 | DNA replication factor C complex(GO:0005663) |
0.0 | 0.3 | GO:0035631 | CD40 receptor complex(GO:0035631) |
0.0 | 0.4 | GO:0030135 | coated vesicle(GO:0030135) |
0.0 | 0.2 | GO:0030140 | trans-Golgi network transport vesicle(GO:0030140) |
0.0 | 1.7 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
0.0 | 2.0 | GO:0005741 | mitochondrial outer membrane(GO:0005741) |
0.0 | 0.7 | GO:0005778 | peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) |
0.0 | 0.1 | GO:0005587 | collagen type IV trimer(GO:0005587) |
0.0 | 1.8 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
0.0 | 0.2 | GO:0005858 | axonemal dynein complex(GO:0005858) axoneme part(GO:0044447) |
0.0 | 0.4 | GO:0045202 | synapse(GO:0045202) |
0.0 | 0.2 | GO:0098643 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
0.0 | 0.0 | GO:0042765 | GPI-anchor transamidase complex(GO:0042765) |
0.0 | 0.3 | GO:0016592 | mediator complex(GO:0016592) |
0.0 | 0.1 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
0.0 | 0.1 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
0.0 | 0.1 | GO:0033018 | sarcoplasmic reticulum lumen(GO:0033018) |
0.0 | 0.7 | GO:0032587 | ruffle membrane(GO:0032587) |
0.0 | 1.1 | GO:0008021 | synaptic vesicle(GO:0008021) |
0.0 | 0.2 | GO:0005796 | Golgi lumen(GO:0005796) |
0.0 | 0.1 | GO:0034399 | nuclear periphery(GO:0034399) |
0.0 | 0.2 | GO:0044431 | Golgi apparatus part(GO:0044431) |
0.0 | 0.0 | GO:0030669 | clathrin-coated endocytic vesicle membrane(GO:0030669) |
0.0 | 0.0 | GO:0016600 | flotillin complex(GO:0016600) |
0.0 | 0.4 | GO:0000776 | kinetochore(GO:0000776) |
0.0 | 0.1 | GO:0031143 | pseudopodium(GO:0031143) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.3 | 3.9 | GO:0015439 | heme-transporting ATPase activity(GO:0015439) |
0.7 | 2.2 | GO:0070361 | mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364) |
0.4 | 3.1 | GO:0008732 | glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732) |
0.4 | 1.3 | GO:0004362 | glutathione-disulfide reductase activity(GO:0004362) |
0.4 | 1.6 | GO:0004727 | prenylated protein tyrosine phosphatase activity(GO:0004727) |
0.4 | 1.4 | GO:0015183 | L-aspartate transmembrane transporter activity(GO:0015183) |
0.4 | 1.1 | GO:0046976 | histone methyltransferase activity (H3-K27 specific)(GO:0046976) |
0.3 | 1.0 | GO:0008263 | pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263) |
0.3 | 1.3 | GO:0032050 | clathrin heavy chain binding(GO:0032050) |
0.2 | 1.0 | GO:0008296 | 3'-5'-exodeoxyribonuclease activity(GO:0008296) |
0.2 | 0.9 | GO:0030060 | L-malate dehydrogenase activity(GO:0030060) |
0.2 | 1.8 | GO:0004563 | beta-N-acetylhexosaminidase activity(GO:0004563) |
0.2 | 0.7 | GO:0003896 | DNA primase activity(GO:0003896) |
0.2 | 0.8 | GO:0004505 | phenylalanine 4-monooxygenase activity(GO:0004505) |
0.2 | 1.0 | GO:0004485 | methylcrotonoyl-CoA carboxylase activity(GO:0004485) |
0.2 | 1.1 | GO:0019238 | cyclohydrolase activity(GO:0019238) |
0.2 | 0.5 | GO:0005329 | dopamine transmembrane transporter activity(GO:0005329) |
0.2 | 1.1 | GO:0008853 | exodeoxyribonuclease III activity(GO:0008853) |
0.2 | 2.0 | GO:0000175 | 3'-5'-exoribonuclease activity(GO:0000175) |
0.2 | 1.1 | GO:0016308 | 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308) |
0.2 | 0.5 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
0.2 | 0.5 | GO:0043426 | histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648) MRF binding(GO:0043426) |
0.2 | 1.2 | GO:0004047 | aminomethyltransferase activity(GO:0004047) |
0.1 | 0.4 | GO:0005381 | iron ion transmembrane transporter activity(GO:0005381) |
0.1 | 0.4 | GO:0004347 | glucose-6-phosphate isomerase activity(GO:0004347) |
0.1 | 1.0 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
0.1 | 1.5 | GO:0061659 | ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659) |
0.1 | 1.0 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
0.1 | 1.2 | GO:0003688 | DNA replication origin binding(GO:0003688) |
0.1 | 0.6 | GO:0070815 | peptidyl-lysine 5-dioxygenase activity(GO:0070815) |
0.1 | 1.8 | GO:0005337 | nucleoside transmembrane transporter activity(GO:0005337) |
0.1 | 2.3 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
0.1 | 0.7 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
0.1 | 1.5 | GO:0004062 | aryl sulfotransferase activity(GO:0004062) |
0.1 | 0.6 | GO:0030911 | TPR domain binding(GO:0030911) |
0.1 | 0.3 | GO:0005224 | ATP-binding and phosphorylation-dependent chloride channel activity(GO:0005224) channel-conductance-controlling ATPase activity(GO:0005260) |
0.1 | 0.5 | GO:0004489 | methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489) |
0.1 | 0.4 | GO:0001849 | complement component C1q binding(GO:0001849) |
0.1 | 0.8 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
0.1 | 0.5 | GO:0035184 | histone threonine kinase activity(GO:0035184) |
0.1 | 0.6 | GO:0015174 | basic amino acid transmembrane transporter activity(GO:0015174) |
0.1 | 0.3 | GO:0016524 | latrotoxin receptor activity(GO:0016524) |
0.1 | 0.5 | GO:0004844 | uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506) |
0.1 | 0.3 | GO:0000033 | alpha-1,3-mannosyltransferase activity(GO:0000033) |
0.1 | 0.4 | GO:0047179 | platelet-activating factor acetyltransferase activity(GO:0047179) |
0.1 | 0.4 | GO:0003951 | NAD+ kinase activity(GO:0003951) |
0.1 | 0.2 | GO:0051880 | G-quadruplex DNA binding(GO:0051880) |
0.1 | 1.6 | GO:0030332 | cyclin binding(GO:0030332) |
0.1 | 0.3 | GO:0004122 | cystathionine beta-synthase activity(GO:0004122) |
0.1 | 0.6 | GO:0004176 | ATP-dependent peptidase activity(GO:0004176) |
0.1 | 1.9 | GO:0005095 | GTPase inhibitor activity(GO:0005095) |
0.1 | 0.4 | GO:0004766 | spermidine synthase activity(GO:0004766) |
0.1 | 0.4 | GO:0044020 | histone methyltransferase activity (H4-R3 specific)(GO:0044020) |
0.1 | 0.2 | GO:0017130 | poly(C) RNA binding(GO:0017130) |
0.1 | 0.5 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
0.1 | 1.4 | GO:0005031 | tumor necrosis factor-activated receptor activity(GO:0005031) |
0.1 | 0.2 | GO:0015141 | thiosulfate transmembrane transporter activity(GO:0015117) succinate transmembrane transporter activity(GO:0015141) |
0.1 | 1.7 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
0.1 | 0.7 | GO:0004550 | nucleoside diphosphate kinase activity(GO:0004550) |
0.1 | 0.4 | GO:0019855 | calcium channel inhibitor activity(GO:0019855) |
0.1 | 2.0 | GO:0015175 | neutral amino acid transmembrane transporter activity(GO:0015175) |
0.1 | 0.4 | GO:0004815 | aspartate-tRNA ligase activity(GO:0004815) |
0.1 | 0.3 | GO:0016404 | 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404) |
0.1 | 0.7 | GO:0016861 | intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861) |
0.1 | 0.2 | GO:0030611 | arsenate reductase activity(GO:0030611) |
0.1 | 1.0 | GO:0005391 | sodium:potassium-exchanging ATPase activity(GO:0005391) |
0.1 | 0.8 | GO:0004707 | MAP kinase activity(GO:0004707) |
0.1 | 0.4 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) |
0.1 | 0.7 | GO:0015355 | secondary active monocarboxylate transmembrane transporter activity(GO:0015355) |
0.1 | 0.1 | GO:0015216 | adenine nucleotide transmembrane transporter activity(GO:0000295) purine nucleotide transmembrane transporter activity(GO:0015216) |
0.1 | 0.4 | GO:0004430 | 1-phosphatidylinositol 4-kinase activity(GO:0004430) |
0.1 | 1.5 | GO:0019213 | deacetylase activity(GO:0019213) |
0.1 | 0.5 | GO:0070087 | chromo shadow domain binding(GO:0070087) |
0.1 | 0.7 | GO:0016918 | retinal binding(GO:0016918) |
0.1 | 0.8 | GO:0005521 | lamin binding(GO:0005521) |
0.1 | 0.8 | GO:0016780 | phosphotransferase activity, for other substituted phosphate groups(GO:0016780) |
0.1 | 0.2 | GO:0015925 | galactosidase activity(GO:0015925) |
0.1 | 0.1 | GO:0016635 | oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635) |
0.1 | 2.0 | GO:0097472 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472) |
0.1 | 0.2 | GO:0004828 | serine-tRNA ligase activity(GO:0004828) |
0.1 | 0.3 | GO:0004367 | glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367) |
0.1 | 0.5 | GO:0009982 | pseudouridine synthase activity(GO:0009982) |
0.1 | 0.2 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
0.1 | 0.2 | GO:0048039 | succinate dehydrogenase activity(GO:0000104) ubiquinone binding(GO:0048039) |
0.0 | 0.7 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
0.0 | 0.9 | GO:0070491 | repressing transcription factor binding(GO:0070491) |
0.0 | 0.1 | GO:0003980 | UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980) |
0.0 | 0.6 | GO:0016892 | endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892) |
0.0 | 0.4 | GO:0004835 | tubulin-tyrosine ligase activity(GO:0004835) |
0.0 | 0.8 | GO:0019992 | diacylglycerol binding(GO:0019992) |
0.0 | 0.0 | GO:0002039 | p53 binding(GO:0002039) |
0.0 | 0.4 | GO:0090599 | alpha-glucosidase activity(GO:0090599) |
0.0 | 1.0 | GO:0004659 | prenyltransferase activity(GO:0004659) |
0.0 | 0.4 | GO:0003691 | double-stranded telomeric DNA binding(GO:0003691) |
0.0 | 0.1 | GO:0043559 | insulin binding(GO:0043559) |
0.0 | 0.2 | GO:0016997 | exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) |
0.0 | 0.8 | GO:0030507 | spectrin binding(GO:0030507) |
0.0 | 0.1 | GO:0003863 | alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863) |
0.0 | 0.2 | GO:0016882 | cyclo-ligase activity(GO:0016882) |
0.0 | 0.1 | GO:0061505 | DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505) |
0.0 | 0.2 | GO:0050220 | prostaglandin-E synthase activity(GO:0050220) |
0.0 | 0.1 | GO:0000156 | phosphorelay response regulator activity(GO:0000156) |
0.0 | 0.1 | GO:0043140 | bubble DNA binding(GO:0000405) ATP-dependent 3'-5' DNA helicase activity(GO:0043140) |
0.0 | 0.1 | GO:0008489 | UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489) |
0.0 | 0.3 | GO:0004703 | G-protein coupled receptor kinase activity(GO:0004703) |
0.0 | 0.4 | GO:0030515 | snoRNA binding(GO:0030515) |
0.0 | 1.2 | GO:0004712 | protein serine/threonine/tyrosine kinase activity(GO:0004712) |
0.0 | 1.2 | GO:0005452 | inorganic anion exchanger activity(GO:0005452) |
0.0 | 0.3 | GO:0015349 | thyroid hormone transmembrane transporter activity(GO:0015349) |
0.0 | 1.9 | GO:0042826 | histone deacetylase binding(GO:0042826) |
0.0 | 0.4 | GO:0045502 | dynein binding(GO:0045502) |
0.0 | 1.4 | GO:0051219 | phosphoprotein binding(GO:0051219) |
0.0 | 1.9 | GO:0003899 | DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062) |
0.0 | 0.3 | GO:0015166 | polyol transmembrane transporter activity(GO:0015166) |
0.0 | 0.2 | GO:0008907 | integrase activity(GO:0008907) |
0.0 | 0.1 | GO:0015386 | potassium:proton antiporter activity(GO:0015386) |
0.0 | 0.3 | GO:0016018 | cyclosporin A binding(GO:0016018) |
0.0 | 0.8 | GO:0070742 | C2H2 zinc finger domain binding(GO:0070742) |
0.0 | 0.8 | GO:0005109 | frizzled binding(GO:0005109) |
0.0 | 0.3 | GO:0055056 | D-glucose transmembrane transporter activity(GO:0055056) |
0.0 | 0.2 | GO:0008269 | JAK pathway signal transduction adaptor activity(GO:0008269) |
0.0 | 0.1 | GO:0033858 | N-acetylgalactosamine kinase activity(GO:0033858) |
0.0 | 0.3 | GO:0003876 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
0.0 | 0.2 | GO:0004616 | phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616) |
0.0 | 0.2 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
0.0 | 0.3 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
0.0 | 0.2 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
0.0 | 0.5 | GO:0070061 | fructose binding(GO:0070061) |
0.0 | 1.5 | GO:0016831 | carboxy-lyase activity(GO:0016831) |
0.0 | 1.0 | GO:0050661 | NADP binding(GO:0050661) |
0.0 | 0.2 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
0.0 | 0.1 | GO:0042608 | T cell receptor binding(GO:0042608) |
0.0 | 0.1 | GO:0004960 | thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961) |
0.0 | 0.4 | GO:0000049 | tRNA binding(GO:0000049) |
0.0 | 0.2 | GO:0003910 | DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910) |
0.0 | 0.1 | GO:0016361 | activin receptor activity, type I(GO:0016361) |
0.0 | 0.1 | GO:0030492 | hemoglobin binding(GO:0030492) |
0.0 | 0.1 | GO:0004591 | oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591) |
0.0 | 0.5 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
0.0 | 1.0 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
0.0 | 0.1 | GO:0004046 | aminoacylase activity(GO:0004046) |
0.0 | 0.2 | GO:0030544 | Hsp70 protein binding(GO:0030544) |
0.0 | 0.1 | GO:0055103 | ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106) |
0.0 | 0.2 | GO:0052654 | branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656) |
0.0 | 0.4 | GO:0051920 | peroxiredoxin activity(GO:0051920) |
0.0 | 2.2 | GO:0050660 | flavin adenine dinucleotide binding(GO:0050660) |
0.0 | 0.2 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
0.0 | 0.2 | GO:0004185 | serine-type carboxypeptidase activity(GO:0004185) |
0.0 | 0.2 | GO:0042978 | ornithine decarboxylase inhibitor activity(GO:0008073) ornithine decarboxylase activator activity(GO:0042978) |
0.0 | 0.1 | GO:0015142 | citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142) |
0.0 | 0.2 | GO:0004340 | glucokinase activity(GO:0004340) |
0.0 | 0.2 | GO:0008158 | hedgehog receptor activity(GO:0008158) |
0.0 | 0.7 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
0.0 | 0.1 | GO:0016531 | copper chaperone activity(GO:0016531) |
0.0 | 0.1 | GO:0016774 | phosphotransferase activity, carboxyl group as acceptor(GO:0016774) |
0.0 | 0.1 | GO:0043008 | ATP-dependent protein binding(GO:0043008) |
0.0 | 0.2 | GO:0042975 | peroxisome proliferator activated receptor binding(GO:0042975) |
0.0 | 0.1 | GO:0008649 | rRNA methyltransferase activity(GO:0008649) |
0.0 | 0.7 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
0.0 | 0.2 | GO:0030020 | extracellular matrix structural constituent conferring tensile strength(GO:0030020) |
0.0 | 0.4 | GO:0004190 | aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001) |
0.0 | 0.1 | GO:0043425 | bHLH transcription factor binding(GO:0043425) |
0.0 | 2.7 | GO:0015631 | tubulin binding(GO:0015631) |
0.0 | 0.3 | GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) |
0.0 | 0.1 | GO:0008898 | S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898) |
0.0 | 0.8 | GO:0017137 | Rab GTPase binding(GO:0017137) |
0.0 | 0.1 | GO:0019826 | oxygen sensor activity(GO:0019826) |
0.0 | 3.0 | GO:0051082 | unfolded protein binding(GO:0051082) |
0.0 | 0.4 | GO:0005522 | profilin binding(GO:0005522) |
0.0 | 1.0 | GO:0016875 | aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876) |
0.0 | 1.0 | GO:0003705 | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705) |
0.0 | 0.6 | GO:0051059 | NF-kappaB binding(GO:0051059) |
0.0 | 0.1 | GO:0016784 | 3-mercaptopyruvate sulfurtransferase activity(GO:0016784) |
0.0 | 0.1 | GO:0008321 | Ral guanyl-nucleotide exchange factor activity(GO:0008321) |
0.0 | 0.1 | GO:0043183 | vascular endothelial growth factor receptor 1 binding(GO:0043183) |
0.0 | 0.0 | GO:0003923 | GPI-anchor transamidase activity(GO:0003923) |
0.0 | 0.1 | GO:0042609 | CD4 receptor binding(GO:0042609) |
0.0 | 0.2 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
0.0 | 0.3 | GO:0016813 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813) |
0.0 | 0.7 | GO:0051539 | 4 iron, 4 sulfur cluster binding(GO:0051539) |
0.0 | 0.1 | GO:0015018 | galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018) |
0.0 | 0.1 | GO:0004971 | AMPA glutamate receptor activity(GO:0004971) |
0.0 | 0.8 | GO:0003725 | double-stranded RNA binding(GO:0003725) |
0.0 | 0.1 | GO:0003689 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
0.0 | 0.3 | GO:0004004 | ATP-dependent RNA helicase activity(GO:0004004) |
0.0 | 0.4 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
0.0 | 0.2 | GO:0031701 | angiotensin receptor binding(GO:0031701) |
0.0 | 0.1 | GO:0019789 | SUMO transferase activity(GO:0019789) |
0.0 | 0.0 | GO:0003706 | obsolete ligand-regulated transcription factor activity(GO:0003706) |
0.0 | 0.1 | GO:0016907 | G-protein coupled acetylcholine receptor activity(GO:0016907) |
0.0 | 0.2 | GO:0031369 | translation initiation factor binding(GO:0031369) |
0.0 | 0.1 | GO:0003990 | acetylcholinesterase activity(GO:0003990) laminin-1 binding(GO:0043237) |
0.0 | 0.2 | GO:0042162 | telomeric DNA binding(GO:0042162) |
0.0 | 1.0 | GO:0008080 | N-acetyltransferase activity(GO:0008080) |
0.0 | 0.1 | GO:0004667 | prostaglandin-D synthase activity(GO:0004667) |
0.0 | 0.1 | GO:0008967 | phosphoglycolate phosphatase activity(GO:0008967) |
0.0 | 0.7 | GO:0030145 | manganese ion binding(GO:0030145) |
0.0 | 0.1 | GO:0016842 | amidine-lyase activity(GO:0016842) |
0.0 | 0.4 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
0.0 | 0.1 | GO:0015926 | glucosidase activity(GO:0015926) |
0.0 | 0.3 | GO:0016500 | protein-hormone receptor activity(GO:0016500) |
0.0 | 1.3 | GO:0016566 | obsolete specific transcriptional repressor activity(GO:0016566) |
0.0 | 0.0 | GO:0005047 | signal recognition particle binding(GO:0005047) |
0.0 | 0.1 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
0.0 | 0.1 | GO:0004518 | nuclease activity(GO:0004518) |
0.0 | 0.2 | GO:0033613 | activating transcription factor binding(GO:0033613) |
0.0 | 0.3 | GO:0001948 | glycoprotein binding(GO:0001948) |
0.0 | 0.0 | GO:0031493 | nucleosomal histone binding(GO:0031493) SAM domain binding(GO:0032093) |
0.0 | 0.2 | GO:0005030 | neurotrophin receptor activity(GO:0005030) |
0.0 | 0.4 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
0.0 | 0.3 | GO:0004467 | long-chain fatty acid-CoA ligase activity(GO:0004467) |
0.0 | 0.1 | GO:0016413 | O-acetyltransferase activity(GO:0016413) |
0.0 | 0.2 | GO:0004065 | arylsulfatase activity(GO:0004065) |
0.0 | 0.2 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617) |
0.0 | 0.1 | GO:0019103 | pyrimidine nucleotide binding(GO:0019103) |
0.0 | 0.2 | GO:0015464 | acetylcholine receptor activity(GO:0015464) |
0.0 | 0.2 | GO:0051117 | ATPase binding(GO:0051117) |
0.0 | 0.3 | GO:0004385 | guanylate kinase activity(GO:0004385) |
0.0 | 0.1 | GO:0005158 | insulin receptor binding(GO:0005158) |
0.0 | 0.3 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
0.0 | 3.3 | GO:0005096 | GTPase activator activity(GO:0005096) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 1.1 | ST_G_ALPHA_S_PATHWAY | G alpha s Pathway |
0.0 | 1.6 | SA_MMP_CYTOKINE_CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
0.0 | 1.0 | SA_REG_CASCADE_OF_CYCLIN_EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
0.0 | 0.4 | ST_STAT3_PATHWAY | STAT3 Pathway |
0.0 | 0.6 | SA_CASPASE_CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
0.0 | 0.1 | SA_TRKA_RECEPTOR | The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth. |
0.0 | 0.2 | ST_GRANULE_CELL_SURVIVAL_PATHWAY | Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway. |
0.0 | 1.0 | ST_T_CELL_SIGNAL_TRANSDUCTION | T Cell Signal Transduction |
0.0 | 0.5 | ST_ERK1_ERK2_MAPK_PATHWAY | ERK1/ERK2 MAPK Pathway |
0.0 | 0.3 | SIG_CD40PATHWAYMAP | Genes related to CD40 signaling |
0.0 | 0.2 | ST_B_CELL_ANTIGEN_RECEPTOR | B Cell Antigen Receptor |