Motif ID: MYBL1
Z-value: 1.388
Transcription factors associated with MYBL1:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| MYBL1 | ENSG00000185697.12 | MYBL1 |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 4.5 | GO:0008228 | opsonization(GO:0008228) |
| 0.6 | 2.6 | GO:0060025 | regulation of synaptic activity(GO:0060025) |
| 0.4 | 1.2 | GO:0060128 | corticotropin hormone secreting cell differentiation(GO:0060128) |
| 0.3 | 2.8 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
| 0.2 | 1.2 | GO:0009082 | branched-chain amino acid biosynthetic process(GO:0009082) |
| 0.2 | 0.7 | GO:0043128 | regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128) |
| 0.1 | 0.4 | GO:0006556 | S-adenosylmethionine biosynthetic process(GO:0006556) |
| 0.1 | 0.3 | GO:0044314 | protein K27-linked ubiquitination(GO:0044314) |
| 0.1 | 0.6 | GO:0006883 | cellular sodium ion homeostasis(GO:0006883) |
| 0.1 | 0.5 | GO:0016080 | synaptic vesicle targeting(GO:0016080) |
| 0.1 | 0.2 | GO:0044240 | multicellular organism lipid catabolic process(GO:0044240) |
| 0.1 | 0.5 | GO:0060100 | regulation of phagocytosis, engulfment(GO:0060099) positive regulation of phagocytosis, engulfment(GO:0060100) regulation of membrane invagination(GO:1905153) positive regulation of membrane invagination(GO:1905155) |
| 0.1 | 0.2 | GO:0070544 | histone H3-K36 demethylation(GO:0070544) |
| 0.1 | 1.3 | GO:0002504 | antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504) |
| 0.0 | 0.1 | GO:0009134 | nucleoside diphosphate catabolic process(GO:0009134) ribonucleoside diphosphate catabolic process(GO:0009191) |
| 0.0 | 0.1 | GO:0019441 | tryptophan catabolic process to kynurenine(GO:0019441) |
| 0.0 | 0.3 | GO:0042989 | sequestering of actin monomers(GO:0042989) |
| 0.0 | 0.5 | GO:0007141 | male meiosis I(GO:0007141) |
| 0.0 | 0.3 | GO:0045056 | transcytosis(GO:0045056) |
| 0.0 | 1.1 | GO:0030199 | collagen fibril organization(GO:0030199) |
| 0.0 | 0.4 | GO:0051205 | protein insertion into membrane(GO:0051205) |
| 0.0 | 0.1 | GO:0006307 | DNA dealkylation involved in DNA repair(GO:0006307) DNA dealkylation(GO:0035510) |
| 0.0 | 0.4 | GO:0071451 | removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748) |
| 0.0 | 0.6 | GO:0045104 | intermediate filament cytoskeleton organization(GO:0045104) |
| 0.0 | 0.2 | GO:1900087 | traversing start control point of mitotic cell cycle(GO:0007089) positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) positive regulation of cell cycle G1/S phase transition(GO:1902808) |
| 0.0 | 0.2 | GO:0015781 | pyrimidine nucleotide-sugar transport(GO:0015781) |
| 0.0 | 3.0 | GO:0051092 | positive regulation of NF-kappaB transcription factor activity(GO:0051092) |
| 0.0 | 0.1 | GO:1904358 | positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358) |
| 0.0 | 0.1 | GO:0051877 | pigment granule aggregation in cell center(GO:0051877) |
| 0.0 | 0.4 | GO:0046415 | urate metabolic process(GO:0046415) |
| 0.0 | 0.1 | GO:0007468 | regulation of rhodopsin gene expression(GO:0007468) |
| 0.0 | 0.1 | GO:0000917 | barrier septum assembly(GO:0000917) cell septum assembly(GO:0090529) mitotic cytokinetic process(GO:1902410) |
| 0.0 | 0.4 | GO:0006525 | arginine metabolic process(GO:0006525) |
| 0.0 | 0.1 | GO:0042262 | DNA protection(GO:0042262) |
| 0.0 | 0.0 | GO:0003350 | pulmonary myocardium development(GO:0003350) |
| 0.0 | 0.0 | GO:0046080 | dUTP metabolic process(GO:0046080) |
| 0.0 | 0.2 | GO:0035024 | negative regulation of Rho protein signal transduction(GO:0035024) |
| 0.0 | 1.0 | GO:0001837 | epithelial to mesenchymal transition(GO:0001837) |
| 0.0 | 0.3 | GO:0045648 | positive regulation of erythrocyte differentiation(GO:0045648) |
| 0.0 | 0.0 | GO:0051311 | meiotic metaphase I plate congression(GO:0043060) spindle midzone assembly(GO:0051255) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311) |
| 0.0 | 0.1 | GO:0070245 | positive regulation of thymocyte apoptotic process(GO:0070245) |
| 0.0 | 0.6 | GO:0042771 | intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771) |
| 0.0 | 0.2 | GO:0050687 | negative regulation of defense response to virus(GO:0050687) |
| 0.0 | 0.1 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway(GO:0048387) |
| 0.0 | 0.2 | GO:0032148 | activation of protein kinase B activity(GO:0032148) |
| 0.0 | 0.2 | GO:0018214 | peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214) |
| 0.0 | 0.3 | GO:0006308 | DNA catabolic process(GO:0006308) |
| 0.0 | 0.0 | GO:0034341 | response to interferon-gamma(GO:0034341) |
| 0.0 | 0.2 | GO:0050930 | induction of positive chemotaxis(GO:0050930) |
| 0.0 | 1.0 | GO:0006334 | nucleosome assembly(GO:0006334) |
| 0.0 | 0.3 | GO:0051225 | spindle assembly(GO:0051225) |
| 0.0 | 0.1 | GO:0000089 | mitotic metaphase(GO:0000089) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 1.1 | GO:0005588 | collagen type V trimer(GO:0005588) |
| 0.2 | 2.8 | GO:0098647 | collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647) |
| 0.2 | 2.5 | GO:0035631 | CD40 receptor complex(GO:0035631) |
| 0.1 | 0.9 | GO:0005678 | obsolete chromatin assembly complex(GO:0005678) |
| 0.1 | 0.6 | GO:1990752 | microtubule plus-end(GO:0035371) microtubule end(GO:1990752) |
| 0.1 | 1.3 | GO:0042613 | MHC class II protein complex(GO:0042613) |
| 0.0 | 0.2 | GO:0005712 | chiasma(GO:0005712) MutLbeta complex(GO:0032390) |
| 0.0 | 0.2 | GO:0030936 | collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936) |
| 0.0 | 0.1 | GO:0019008 | molybdopterin synthase complex(GO:0019008) |
| 0.0 | 0.3 | GO:0016012 | sarcoglycan complex(GO:0016012) |
| 0.0 | 0.6 | GO:0001673 | male germ cell nucleus(GO:0001673) |
| 0.0 | 0.4 | GO:0030897 | HOPS complex(GO:0030897) |
| 0.0 | 1.0 | GO:0005776 | autophagosome(GO:0005776) |
| 0.0 | 0.2 | GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex(GO:0031464) |
| 0.0 | 0.5 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.0 | 1.3 | GO:0030672 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
| 0.0 | 1.8 | GO:0070469 | respiratory chain(GO:0070469) |
| 0.0 | 1.0 | GO:0043005 | neuron projection(GO:0043005) |
| 0.0 | 0.2 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.0 | 0.4 | GO:0016592 | mediator complex(GO:0016592) |
| 0.0 | 2.4 | GO:0016607 | nuclear speck(GO:0016607) |
| 0.0 | 0.1 | GO:0000796 | condensin complex(GO:0000796) |
| 0.0 | 0.4 | GO:0005811 | lipid particle(GO:0005811) |
| 0.0 | 0.1 | GO:0034464 | BBSome(GO:0034464) |
| 0.0 | 0.4 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 0.0 | 0.1 | GO:0005719 | nuclear euchromatin(GO:0005719) |
| 0.0 | 1.0 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 4.5 | GO:0030247 | pattern binding(GO:0001871) polysaccharide binding(GO:0030247) |
| 0.2 | 1.2 | GO:0052654 | branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656) |
| 0.1 | 0.3 | GO:0016309 | 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309) |
| 0.1 | 2.7 | GO:0004129 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 0.1 | 0.5 | GO:0042043 | neurexin family protein binding(GO:0042043) |
| 0.1 | 0.9 | GO:0050811 | GABA receptor binding(GO:0050811) |
| 0.1 | 0.5 | GO:0070892 | lipoteichoic acid receptor activity(GO:0070892) |
| 0.1 | 0.7 | GO:0004157 | dihydropyrimidinase activity(GO:0004157) |
| 0.1 | 0.4 | GO:0003956 | NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956) |
| 0.1 | 2.8 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.1 | 1.2 | GO:0017134 | fibroblast growth factor binding(GO:0017134) |
| 0.1 | 1.0 | GO:0050786 | RAGE receptor binding(GO:0050786) |
| 0.0 | 0.1 | GO:0004833 | tryptophan 2,3-dioxygenase activity(GO:0004833) |
| 0.0 | 0.7 | GO:0004745 | retinol dehydrogenase activity(GO:0004745) |
| 0.0 | 0.4 | GO:0004784 | superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721) |
| 0.0 | 0.1 | GO:0030611 | arsenate reductase activity(GO:0030611) |
| 0.0 | 0.6 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
| 0.0 | 0.6 | GO:0008494 | translation activator activity(GO:0008494) |
| 0.0 | 0.2 | GO:0042577 | lipid phosphatase activity(GO:0042577) |
| 0.0 | 0.7 | GO:0030742 | GTP-dependent protein binding(GO:0030742) |
| 0.0 | 0.8 | GO:0004697 | protein kinase C activity(GO:0004697) |
| 0.0 | 0.5 | GO:0019992 | diacylglycerol binding(GO:0019992) |
| 0.0 | 0.1 | GO:0050815 | phosphoserine binding(GO:0050815) |
| 0.0 | 0.2 | GO:0017049 | GTP-Rho binding(GO:0017049) |
| 0.0 | 0.2 | GO:0015165 | pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165) |
| 0.0 | 0.4 | GO:0032395 | MHC class II receptor activity(GO:0032395) |
| 0.0 | 0.6 | GO:0051861 | glycolipid binding(GO:0051861) |
| 0.0 | 0.2 | GO:0051864 | histone demethylase activity (H3-K36 specific)(GO:0051864) |
| 0.0 | 0.2 | GO:0032052 | bile acid binding(GO:0032052) calcium-dependent phospholipase A2 activity(GO:0047498) |
| 0.0 | 0.1 | GO:0003696 | satellite DNA binding(GO:0003696) |
| 0.0 | 0.2 | GO:0004176 | ATP-dependent peptidase activity(GO:0004176) |
| 0.0 | 0.4 | GO:0015347 | sodium-independent organic anion transmembrane transporter activity(GO:0015347) |
| 0.0 | 0.6 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
| 0.0 | 0.2 | GO:0016681 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
| 0.0 | 0.1 | GO:0017110 | nucleoside-diphosphatase activity(GO:0017110) |
| 0.0 | 0.2 | GO:0004835 | tubulin-tyrosine ligase activity(GO:0004835) |
| 0.0 | 0.3 | GO:0016888 | endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888) |
| 0.0 | 0.1 | GO:0098847 | single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847) |
| 0.0 | 0.2 | GO:0043422 | protein kinase B binding(GO:0043422) |
| 0.0 | 0.4 | GO:0001104 | RNA polymerase II transcription cofactor activity(GO:0001104) |
| 0.0 | 0.0 | GO:0004170 | dUTP diphosphatase activity(GO:0004170) |
| 0.0 | 3.1 | GO:0003702 | obsolete RNA polymerase II transcription factor activity(GO:0003702) |
| 0.0 | 1.1 | GO:0046332 | SMAD binding(GO:0046332) |
| 0.0 | 0.4 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
| 0.0 | 0.2 | GO:0030546 | receptor activator activity(GO:0030546) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 4.5 | ST_MYOCYTE_AD_PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
| 0.0 | 2.5 | SIG_CD40PATHWAYMAP | Genes related to CD40 signaling |
