Motif ID: MZF1

Z-value: 1.811


Transcription factors associated with MZF1:

Gene SymbolEntrez IDGene Name
MZF1 ENSG00000099326.4 MZF1



Activity profile for motif MZF1.

activity profile for motif MZF1


Sorted Z-values histogram for motif MZF1

Sorted Z-values for motif MZF1



Network of associatons between targets according to the STRING database.



First level regulatory network of MZF1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_+_31608054 2.486 ENST00000320985.10
ENST00000361642.5
ENST00000560721.2
ENST00000558440.1
ENST00000424869.1
ENST00000542815.3
ZEB1





zinc finger E-box binding homeobox 1





chr1_-_32801825 1.984 ENST00000329421.7
MARCKSL1
MARCKS-like 1
chr4_-_84035868 1.514 ENST00000426923.2
ENST00000509973.1
PLAC8

placenta-specific 8

chrX_-_70474499 1.453 ENST00000353904.2
ZMYM3
zinc finger, MYM-type 3
chr4_-_84035905 1.452 ENST00000311507.4
PLAC8
placenta-specific 8
chr14_-_23285011 1.402 ENST00000397532.3
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr5_-_81046904 1.322 ENST00000515395.1
SSBP2
single-stranded DNA binding protein 2
chr5_-_81046841 1.306 ENST00000509013.2
ENST00000505980.1
ENST00000509053.1
SSBP2


single-stranded DNA binding protein 2


chrX_+_23352133 1.300 ENST00000379361.4
PTCHD1
patched domain containing 1
chr15_-_37392703 1.286 ENST00000382766.2
ENST00000444725.1
MEIS2

Meis homeobox 2

chrX_-_135849484 1.255 ENST00000370620.1
ENST00000535227.1
ARHGEF6

Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6

chr15_-_37392086 1.219 ENST00000561208.1
MEIS2
Meis homeobox 2
chr14_-_23285069 1.185 ENST00000554758.1
ENST00000397528.4
SLC7A7

solute carrier family 7 (amino acid transporter light chain, y+L system), member 7

chr20_+_34742650 1.182 ENST00000373945.1
ENST00000338074.2
EPB41L1

erythrocyte membrane protein band 4.1-like 1

chr12_-_91576429 1.142 ENST00000552145.1
ENST00000546745.1
DCN

decorin

chr19_-_39108568 1.129 ENST00000586296.1
MAP4K1
mitogen-activated protein kinase kinase kinase kinase 1
chr19_+_50922187 1.086 ENST00000595883.1
ENST00000597855.1
ENST00000596074.1
ENST00000439922.2
ENST00000594685.1
ENST00000270632.7
SPIB





Spi-B transcription factor (Spi-1/PU.1 related)





chr12_-_91576750 1.063 ENST00000228329.5
ENST00000303320.3
ENST00000052754.5
DCN


decorin


chr5_-_81046922 1.058 ENST00000514493.1
ENST00000320672.4
SSBP2

single-stranded DNA binding protein 2

chr1_+_99729813 1.049 ENST00000457765.1
LPPR4
Lipid phosphate phosphatase-related protein type 4
chr12_-_91576561 1.018 ENST00000547568.2
ENST00000552962.1
DCN

decorin

chr2_-_175499294 1.017 ENST00000392547.2
WIPF1
WAS/WASL interacting protein family, member 1
chr17_+_39969183 1.006 ENST00000321562.4
FKBP10
FK506 binding protein 10, 65 kDa
chr12_+_94542459 0.929 ENST00000258526.4
PLXNC1
plexin C1
chr19_-_39826639 0.928 ENST00000602185.1
ENST00000598034.1
ENST00000601387.1
ENST00000595636.1
ENST00000253054.8
ENST00000594700.1
ENST00000597595.1
GMFG






glia maturation factor, gamma






chr7_+_114562172 0.917 ENST00000393486.1
ENST00000257724.3
MDFIC

MyoD family inhibitor domain containing

chr6_-_137113604 0.909 ENST00000359015.4
MAP3K5
mitogen-activated protein kinase kinase kinase 5
chr4_+_129730779 0.899 ENST00000226319.6
PHF17
jade family PHD finger 1
chr8_+_28174649 0.880 ENST00000301908.3
PNOC
prepronociceptin
chr17_-_36904437 0.870 ENST00000585100.1
ENST00000360797.2
ENST00000578109.1
ENST00000579882.1
PCGF2



polycomb group ring finger 2



chr12_+_7167980 0.851 ENST00000360817.5
ENST00000402681.3
C1S

complement component 1, s subcomponent

chr10_+_120967072 0.849 ENST00000392870.2
GRK5
G protein-coupled receptor kinase 5
chr4_+_129730947 0.842 ENST00000452328.2
ENST00000504089.1
PHF17

jade family PHD finger 1

chr8_+_123793633 0.835 ENST00000314393.4
ZHX2
zinc fingers and homeoboxes 2
chr15_-_48937982 0.831 ENST00000316623.5
FBN1
fibrillin 1
chr9_-_35650900 0.830 ENST00000259608.3
SIT1
signaling threshold regulating transmembrane adaptor 1
chr9_+_2015335 0.814 ENST00000349721.2
ENST00000357248.2
ENST00000450198.1
SMARCA2


SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2


chr2_+_30454390 0.810 ENST00000395323.3
ENST00000406087.1
ENST00000404397.1
LBH


limb bud and heart development


chr19_+_16435625 0.777 ENST00000248071.5
ENST00000592003.1
KLF2

Kruppel-like factor 2

chr1_+_209941827 0.763 ENST00000367023.1
TRAF3IP3
TRAF3 interacting protein 3
chrX_-_70474910 0.752 ENST00000373988.1
ENST00000373998.1
ZMYM3

zinc finger, MYM-type 3

chr2_+_219283815 0.747 ENST00000248444.5
ENST00000454069.1
ENST00000392114.2
VIL1


villin 1


chr6_-_32157947 0.744 ENST00000375050.4
PBX2
pre-B-cell leukemia homeobox 2
chr17_+_7155343 0.743 ENST00000573513.1
ENST00000354429.2
ENST00000574255.1
ENST00000396627.2
ENST00000356683.2
ELP5




elongator acetyltransferase complex subunit 5




chr16_+_69958887 0.717 ENST00000568684.1
WWP2
WW domain containing E3 ubiquitin protein ligase 2
chr10_+_114710425 0.714 ENST00000352065.5
ENST00000369395.1
TCF7L2

transcription factor 7-like 2 (T-cell specific, HMG-box)

chr7_+_94285637 0.709 ENST00000482108.1
ENST00000488574.1
PEG10

paternally expressed 10

chr2_-_175547571 0.703 ENST00000409415.3
ENST00000359761.3
ENST00000272746.5
WIPF1


WAS/WASL interacting protein family, member 1


chr9_+_71320557 0.695 ENST00000541509.1
PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr1_+_150245177 0.692 ENST00000369098.3
C1orf54
chromosome 1 open reading frame 54
chr15_-_37391614 0.683 ENST00000219869.9
MEIS2
Meis homeobox 2
chr5_+_133451254 0.680 ENST00000517851.1
ENST00000521639.1
ENST00000522375.1
ENST00000378560.4
ENST00000432532.2
ENST00000520958.1
ENST00000518915.1
ENST00000395023.1
TCF7







transcription factor 7 (T-cell specific, HMG-box)







chr20_+_35201857 0.674 ENST00000373874.2
TGIF2
TGFB-induced factor homeobox 2
chr20_+_57466629 0.669 ENST00000371081.1
ENST00000338783.6
GNAS

GNAS complex locus

chr1_-_212873267 0.667 ENST00000243440.1
BATF3
basic leucine zipper transcription factor, ATF-like 3
chr6_-_32160622 0.666 ENST00000487761.1
ENST00000375040.3
GPSM3

G-protein signaling modulator 3

chr7_+_138145076 0.655 ENST00000343526.4
TRIM24
tripartite motif containing 24
chr9_+_126773880 0.653 ENST00000373615.4
LHX2
LIM homeobox 2
chr13_-_52027134 0.651 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
INTS6




integrator complex subunit 6




chr7_-_94285472 0.650 ENST00000437425.2
ENST00000447873.1
ENST00000415788.2
SGCE


sarcoglycan, epsilon


chr1_-_183560011 0.646 ENST00000367536.1
NCF2
neutrophil cytosolic factor 2
chrX_-_130423240 0.645 ENST00000370910.1
ENST00000370901.4
IGSF1

immunoglobulin superfamily, member 1

chr7_-_94285511 0.644 ENST00000265735.7
SGCE
sarcoglycan, epsilon
chr7_-_94285402 0.638 ENST00000428696.2
ENST00000445866.2
SGCE

sarcoglycan, epsilon

chr3_+_110790590 0.623 ENST00000485303.1
PVRL3
poliovirus receptor-related 3
chr6_+_134210243 0.620 ENST00000367882.4
TCF21
transcription factor 21
chr2_-_61697862 0.617 ENST00000398571.2
USP34
ubiquitin specific peptidase 34
chr14_+_24099318 0.614 ENST00000432832.2
DHRS2
dehydrogenase/reductase (SDR family) member 2
chr1_-_53018654 0.612 ENST00000257177.4
ENST00000355809.4
ENST00000528642.1
ENST00000470626.1
ENST00000371544.3
ZCCHC11




zinc finger, CCHC domain containing 11




chr10_+_114710516 0.605 ENST00000542695.1
ENST00000346198.4
TCF7L2

transcription factor 7-like 2 (T-cell specific, HMG-box)

chr11_-_46142615 0.604 ENST00000529734.1
ENST00000323180.6
PHF21A

PHD finger protein 21A

chr2_+_241564655 0.600 ENST00000407714.1
GPR35
G protein-coupled receptor 35
chr12_+_59989791 0.596 ENST00000552432.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chr11_-_116708302 0.594 ENST00000375320.1
ENST00000359492.2
ENST00000375329.2
ENST00000375323.1
APOA1



apolipoprotein A-I



chr19_-_39108643 0.587 ENST00000396857.2
MAP4K1
mitogen-activated protein kinase kinase kinase kinase 1
chr22_-_21579843 0.585 ENST00000405188.4
GGT2
gamma-glutamyltransferase 2
chr6_+_42749759 0.583 ENST00000314073.5
GLTSCR1L
GLTSCR1-like
chr13_-_96296944 0.582 ENST00000361396.2
ENST00000376829.2
DZIP1

DAZ interacting zinc finger protein 1

chr2_-_61765315 0.579 ENST00000406957.1
ENST00000401558.2
XPO1

exportin 1 (CRM1 homolog, yeast)

chr10_+_7745232 0.577 ENST00000358415.4
ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr12_-_103310987 0.574 ENST00000307000.2
PAH
phenylalanine hydroxylase
chr16_+_30675654 0.573 ENST00000287468.5
ENST00000395073.2
FBRS

fibrosin

chr15_-_37390482 0.569 ENST00000559085.1
ENST00000397624.3
MEIS2

Meis homeobox 2

chr8_-_121824374 0.568 ENST00000517992.1
SNTB1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr1_+_211433275 0.565 ENST00000367005.4
RCOR3
REST corepressor 3
chr17_-_40833858 0.565 ENST00000332438.4
CCR10
chemokine (C-C motif) receptor 10
chr19_+_36195429 0.562 ENST00000392197.2
ZBTB32
zinc finger and BTB domain containing 32
chr22_+_40322595 0.558 ENST00000420971.1
ENST00000544756.1
GRAP2

GRB2-related adaptor protein 2

chr17_-_76921459 0.555 ENST00000262768.7
TIMP2
TIMP metallopeptidase inhibitor 2
chr22_+_40322623 0.553 ENST00000399090.2
GRAP2
GRB2-related adaptor protein 2
chr10_+_7745303 0.551 ENST00000429820.1
ENST00000379587.4
ITIH2

inter-alpha-trypsin inhibitor heavy chain 2

chr7_+_90339169 0.550 ENST00000436577.2
CDK14
cyclin-dependent kinase 14
chr19_+_926000 0.549 ENST00000263620.3
ARID3A
AT rich interactive domain 3A (BRIGHT-like)
chr15_+_89346699 0.546 ENST00000558207.1
ACAN
aggrecan
chr11_-_57283159 0.544 ENST00000533263.1
ENST00000278426.3
SLC43A1

solute carrier family 43 (amino acid system L transporter), member 1

chr13_+_98795434 0.543 ENST00000376586.2
FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr17_+_76210367 0.542 ENST00000592734.1
ENST00000587746.1
BIRC5

baculoviral IAP repeat containing 5

chr16_+_88872176 0.538 ENST00000569140.1
CDT1
chromatin licensing and DNA replication factor 1
chr13_+_98795505 0.534 ENST00000319562.6
FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr11_-_117747327 0.534 ENST00000584230.1
ENST00000527429.1
ENST00000584394.1
ENST00000532984.1
FXYD6


FXYD6-FXYD2
FXYD domain containing ion transport regulator 6


FXYD6-FXYD2 readthrough
chr22_+_40342819 0.532 ENST00000407075.3
GRAP2
GRB2-related adaptor protein 2
chr19_-_39108552 0.532 ENST00000591517.1
MAP4K1
mitogen-activated protein kinase kinase kinase kinase 1
chrX_-_130423200 0.529 ENST00000361420.3
IGSF1
immunoglobulin superfamily, member 1
chr17_-_47841485 0.529 ENST00000506156.1
ENST00000240364.2
FAM117A

family with sequence similarity 117, member A

chr5_+_137688285 0.523 ENST00000314358.5
KDM3B
lysine (K)-specific demethylase 3B
chr10_+_76586348 0.521 ENST00000372724.1
ENST00000287239.4
ENST00000372714.1
KAT6B


K(lysine) acetyltransferase 6B


chrX_-_70473957 0.514 ENST00000373984.3
ENST00000314425.5
ENST00000373982.1
ZMYM3


zinc finger, MYM-type 3


chr10_+_21823079 0.514 ENST00000377100.3
ENST00000377072.3
ENST00000446906.2
MLLT10


myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10


chr17_+_41003166 0.511 ENST00000308423.2
AOC3
amine oxidase, copper containing 3
chr17_-_20370847 0.510 ENST00000423676.3
ENST00000324290.5
LGALS9B

lectin, galactoside-binding, soluble, 9B

chr19_+_10381769 0.510 ENST00000423829.2
ENST00000588645.1
ICAM1

intercellular adhesion molecule 1

chr2_-_172017393 0.509 ENST00000442919.2
TLK1
tousled-like kinase 1
chr6_-_119670919 0.507 ENST00000368468.3
MAN1A1
mannosidase, alpha, class 1A, member 1
chr4_+_37892682 0.504 ENST00000508802.1
ENST00000261439.4
ENST00000402522.1
TBC1D1


TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1


chr3_-_171177852 0.500 ENST00000284483.8
ENST00000475336.1
ENST00000357327.5
ENST00000460047.1
ENST00000488470.1
ENST00000470834.1
TNIK





TRAF2 and NCK interacting kinase





chr12_-_24103954 0.500 ENST00000441133.2
ENST00000545921.1
SOX5

SRY (sex determining region Y)-box 5

chr15_+_75074410 0.497 ENST00000439220.2
CSK
c-src tyrosine kinase
chr5_-_131826457 0.467 ENST00000437654.1
ENST00000245414.4
IRF1

interferon regulatory factor 1

chr17_-_56065484 0.465 ENST00000581208.1
VEZF1
vascular endothelial zinc finger 1
chr10_-_23003460 0.462 ENST00000376573.4
PIP4K2A
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
chr3_+_98250743 0.459 ENST00000284311.3
GPR15
G protein-coupled receptor 15
chr7_+_50344289 0.456 ENST00000413698.1
ENST00000359197.5
ENST00000331340.3
ENST00000357364.4
ENST00000343574.5
ENST00000349824.4
ENST00000346667.4
ENST00000440768.2
IKZF1







IKAROS family zinc finger 1 (Ikaros)







chr6_-_46293378 0.454 ENST00000330430.6
RCAN2
regulator of calcineurin 2
chr10_+_76585303 0.454 ENST00000372725.1
KAT6B
K(lysine) acetyltransferase 6B
chr11_-_46142948 0.452 ENST00000257821.4
PHF21A
PHD finger protein 21A
chr14_+_66975213 0.452 ENST00000543237.1
ENST00000305960.9
GPHN

gephyrin

chr17_+_7155819 0.449 ENST00000570322.1
ENST00000576496.1
ENST00000574841.2
ELP5


elongator acetyltransferase complex subunit 5


chr18_-_6414884 0.449 ENST00000317931.7
ENST00000284898.6
ENST00000400104.3
L3MBTL4


l(3)mbt-like 4 (Drosophila)


chr1_-_150208498 0.448 ENST00000314136.8
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr22_-_32058166 0.447 ENST00000435900.1
ENST00000336566.4
PISD

phosphatidylserine decarboxylase

chr12_-_123011476 0.447 ENST00000528279.1
ENST00000344591.4
ENST00000526560.2
RSRC2


arginine/serine-rich coiled-coil 2


chr1_-_183559693 0.444 ENST00000367535.3
ENST00000413720.1
ENST00000418089.1
NCF2


neutrophil cytosolic factor 2


chr19_+_36195467 0.442 ENST00000426659.2
ZBTB32
zinc finger and BTB domain containing 32
chr6_-_152957944 0.441 ENST00000423061.1
SYNE1
spectrin repeat containing, nuclear envelope 1
chr6_+_31865552 0.440 ENST00000469372.1
ENST00000497706.1
C2

complement component 2

chr2_+_46926048 0.438 ENST00000306503.5
SOCS5
suppressor of cytokine signaling 5
chr16_+_69599861 0.438 ENST00000354436.2
NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr14_-_71107921 0.432 ENST00000500016.1
ENST00000553982.1
CTD-2540L5.6
CTD-2540L5.5
CTD-2540L5.6
CTD-2540L5.5
chr8_-_81083341 0.430 ENST00000519303.2
TPD52
tumor protein D52
chr1_-_151431909 0.429 ENST00000361398.3
ENST00000271715.2
POGZ

pogo transposable element with ZNF domain

chr2_-_217560248 0.427 ENST00000233813.4
IGFBP5
insulin-like growth factor binding protein 5
chr17_-_41739283 0.425 ENST00000393661.2
ENST00000318579.4
MEOX1

mesenchyme homeobox 1

chr2_+_182321925 0.425 ENST00000339307.4
ENST00000397033.2
ITGA4

integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)

chr1_+_155829286 0.422 ENST00000368324.4
SYT11
synaptotagmin XI
chrX_-_119694538 0.420 ENST00000371322.5
CUL4B
cullin 4B
chr11_-_2160180 0.419 ENST00000381406.4
IGF2
insulin-like growth factor 2 (somatomedin A)
chr2_-_60780607 0.418 ENST00000537768.1
ENST00000335712.6
ENST00000356842.4
BCL11A


B-cell CLL/lymphoma 11A (zinc finger protein)


chr3_+_8543393 0.412 ENST00000157600.3
ENST00000415597.1
ENST00000535732.1
LMCD1


LIM and cysteine-rich domains 1


chr6_+_87865262 0.410 ENST00000369577.3
ENST00000518845.1
ENST00000339907.4
ENST00000496806.2
ZNF292



zinc finger protein 292



chr18_-_53255766 0.408 ENST00000566286.1
ENST00000564999.1
ENST00000566279.1
ENST00000354452.3
ENST00000356073.4
TCF4




transcription factor 4




chr12_+_53399942 0.408 ENST00000262056.9
EIF4B
eukaryotic translation initiation factor 4B
chr5_-_169725231 0.406 ENST00000046794.5
LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr3_+_73045936 0.401 ENST00000356692.5
ENST00000488810.1
ENST00000394284.3
ENST00000295862.9
ENST00000495566.1
PPP4R2




protein phosphatase 4, regulatory subunit 2




chr1_-_226924980 0.399 ENST00000272117.3
ITPKB
inositol-trisphosphate 3-kinase B
chr20_+_8112824 0.398 ENST00000378641.3
PLCB1
phospholipase C, beta 1 (phosphoinositide-specific)
chr17_+_65373531 0.397 ENST00000580974.1
PITPNC1
phosphatidylinositol transfer protein, cytoplasmic 1
chr1_+_211432593 0.395 ENST00000367006.4
RCOR3
REST corepressor 3
chr1_-_150208412 0.393 ENST00000532744.1
ENST00000369114.5
ENST00000369115.2
ENST00000369116.4
ANP32E



acidic (leucine-rich) nuclear phosphoprotein 32 family, member E



chr6_+_106546808 0.389 ENST00000369089.3
PRDM1
PR domain containing 1, with ZNF domain
chr12_-_81331697 0.385 ENST00000552864.1
LIN7A
lin-7 homolog A (C. elegans)
chr19_-_6670128 0.384 ENST00000245912.3
TNFSF14
tumor necrosis factor (ligand) superfamily, member 14
chr1_+_100315613 0.380 ENST00000361915.3
AGL
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
chr22_-_31741757 0.379 ENST00000215919.3
PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr6_+_37137939 0.378 ENST00000373509.5
PIM1
pim-1 oncogene
chr17_-_65241281 0.372 ENST00000358691.5
ENST00000580168.1
HELZ

helicase with zinc finger

chr14_+_102228123 0.371 ENST00000422945.2
ENST00000554442.1
ENST00000556260.2
ENST00000328724.5
ENST00000557268.1
PPP2R5C




protein phosphatase 2, regulatory subunit B', gamma




chr22_-_39268308 0.370 ENST00000407418.3
CBX6
chromobox homolog 6
chr3_+_8543561 0.370 ENST00000397386.3
LMCD1
LIM and cysteine-rich domains 1
chr14_-_36278454 0.369 ENST00000307138.6
RALGAPA1
Ral GTPase activating protein, alpha subunit 1 (catalytic)
chr1_+_27022839 0.366 ENST00000457599.2
ARID1A
AT rich interactive domain 1A (SWI-like)
chr19_+_3178736 0.366 ENST00000246115.3
S1PR4
sphingosine-1-phosphate receptor 4
chr2_+_46926326 0.365 ENST00000394861.2
SOCS5
suppressor of cytokine signaling 5
chr14_-_36278412 0.365 ENST00000389698.3
ENST00000258840.6
RALGAPA1

Ral GTPase activating protein, alpha subunit 1 (catalytic)

chr17_-_41738931 0.362 ENST00000329168.3
ENST00000549132.1
MEOX1

mesenchyme homeobox 1

chr1_+_150337144 0.361 ENST00000539519.1
ENST00000369067.3
ENST00000369068.4
RPRD2


regulation of nuclear pre-mRNA domain containing 2


chr1_+_150337100 0.359 ENST00000401000.4
RPRD2
regulation of nuclear pre-mRNA domain containing 2
chr18_+_19749386 0.355 ENST00000269216.3
GATA6
GATA binding protein 6
chr1_-_150208363 0.353 ENST00000436748.2
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr12_+_57943781 0.353 ENST00000455537.2
ENST00000286452.5
KIF5A

kinesin family member 5A

chr14_-_64971288 0.352 ENST00000394715.1
ZBTB25
zinc finger and BTB domain containing 25
chr10_-_88854518 0.349 ENST00000277865.4
GLUD1
glutamate dehydrogenase 1
chr6_+_108487245 0.347 ENST00000368986.4
NR2E1
nuclear receptor subfamily 2, group E, member 1
chr19_-_39330818 0.347 ENST00000594769.1
ENST00000602021.1
AC104534.3

Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial

chr17_+_7155556 0.346 ENST00000570500.1
ENST00000574993.1
ENST00000396628.2
ENST00000573657.1
ELP5



elongator acetyltransferase complex subunit 5



chr15_-_70388599 0.346 ENST00000560996.1
ENST00000558201.1
TLE3

transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)

chr20_+_34680620 0.342 ENST00000430276.1
ENST00000373950.2
ENST00000452261.1
EPB41L1


erythrocyte membrane protein band 4.1-like 1


chr21_-_47575481 0.341 ENST00000291670.5
ENST00000397748.1
ENST00000359679.2
ENST00000355384.2
ENST00000397746.3
ENST00000397743.1
FTCD





formimidoyltransferase cyclodeaminase





chr7_+_90338712 0.340 ENST00000265741.3
ENST00000406263.1
CDK14

cyclin-dependent kinase 14

chr3_-_114343039 0.338 ENST00000481632.1
ZBTB20
zinc finger and BTB domain containing 20
chr14_+_75745477 0.337 ENST00000303562.4
ENST00000554617.1
ENST00000554212.1
ENST00000535987.1
ENST00000555242.1
FOS




FBJ murine osteosarcoma viral oncogene homolog




chrX_+_100878079 0.334 ENST00000471229.2
ARMCX3
armadillo repeat containing, X-linked 3
chr1_+_100316041 0.330 ENST00000370165.3
ENST00000370163.3
ENST00000294724.4
AGL


amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase


chr17_+_4613776 0.330 ENST00000269260.2
ARRB2
arrestin, beta 2
chr2_-_220173685 0.329 ENST00000423636.2
ENST00000442029.1
ENST00000412847.1
PTPRN


protein tyrosine phosphatase, receptor type, N


chr20_+_35201993 0.328 ENST00000373872.4
TGIF2
TGFB-induced factor homeobox 2
chr4_-_120550146 0.326 ENST00000354960.3
PDE5A
phosphodiesterase 5A, cGMP-specific
chr4_+_113970772 0.325 ENST00000504454.1
ENST00000394537.3
ENST00000357077.4
ENST00000264366.6
ANK2



ankyrin 2, neuronal



chr17_-_7590745 0.325 ENST00000514944.1
ENST00000503591.1
ENST00000455263.2
ENST00000420246.2
ENST00000445888.2
ENST00000509690.1
ENST00000604348.1
ENST00000269305.4
TP53







tumor protein p53







chr17_-_53800217 0.325 ENST00000424486.2
TMEM100
transmembrane protein 100
chr7_-_79082867 0.323 ENST00000419488.1
ENST00000354212.4
MAGI2

membrane associated guanylate kinase, WW and PDZ domain containing 2


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.3 1.0 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.3 2.1 GO:0034616 response to laminar fluid shear stress(GO:0034616)
0.3 3.2 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.3 2.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.3 0.8 GO:0043371 negative regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043371) negative regulation of T-helper cell differentiation(GO:0045623) negative regulation of CD4-positive, alpha-beta T cell activation(GO:2000515)
0.3 0.8 GO:0001757 somite specification(GO:0001757)
0.2 0.7 GO:0010586 miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.2 1.8 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.2 0.7 GO:1901419 regulation of response to alcohol(GO:1901419)
0.2 0.6 GO:0002740 negative regulation of cytokine secretion involved in immune response(GO:0002740)
0.2 0.6 GO:0021896 forebrain astrocyte differentiation(GO:0021896) forebrain astrocyte development(GO:0021897)
0.2 0.7 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.2 0.9 GO:0045953 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032) negative regulation of natural killer cell mediated immunity(GO:0002716) negative regulation of natural killer cell mediated cytotoxicity(GO:0045953)
0.2 0.7 GO:0006848 pyruvate transport(GO:0006848)
0.2 0.5 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.1 1.5 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.1 0.3 GO:0045750 obsolete positive regulation of S phase of mitotic cell cycle(GO:0045750)
0.1 0.4 GO:0070672 response to interleukin-12(GO:0070671) response to interleukin-15(GO:0070672)
0.1 0.6 GO:0001661 conditioned taste aversion(GO:0001661)
0.1 0.8 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.1 0.4 GO:0071635 negative regulation of transforming growth factor beta production(GO:0071635)
0.1 1.2 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.1 0.9 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.1 0.3 GO:0052805 histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.1 0.3 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.1 0.3 GO:0003289 septum primum development(GO:0003284) atrial septum primum morphogenesis(GO:0003289)
0.1 0.7 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.1 0.2 GO:2000794 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000794)
0.1 0.5 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 0.4 GO:0071168 protein localization to chromatin(GO:0071168)
0.1 0.5 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.1 0.9 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.1 0.2 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.1 1.0 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.1 0.4 GO:0046778 modification by virus of host mRNA processing(GO:0046778)
0.1 0.4 GO:0060744 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.1 0.7 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.1 0.3 GO:0035470 positive regulation of vascular wound healing(GO:0035470)
0.1 0.5 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 0.7 GO:0046146 tetrahydrobiopterin metabolic process(GO:0046146)
0.1 0.5 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.1 0.4 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1 0.2 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.1 0.2 GO:0006562 proline catabolic process(GO:0006562)
0.1 0.2 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.1 1.0 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.1 0.2 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.3 GO:0070208 protein heterotrimerization(GO:0070208)
0.1 0.1 GO:0003197 endocardial cushion development(GO:0003197)
0.1 0.7 GO:0048557 embryonic digestive tract morphogenesis(GO:0048557)
0.1 0.6 GO:0043011 myeloid dendritic cell differentiation(GO:0043011) dendritic cell differentiation(GO:0097028)
0.1 0.4 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.1 0.3 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.1 0.3 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.1 0.2 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.1 0.7 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 0.4 GO:0006196 AMP catabolic process(GO:0006196)
0.1 0.3 GO:0032486 Rap protein signal transduction(GO:0032486)
0.1 0.7 GO:0016180 snRNA processing(GO:0016180)
0.1 0.2 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 0.2 GO:0045759 negative regulation of action potential(GO:0045759)
0.1 0.3 GO:0032736 positive regulation of interleukin-13 production(GO:0032736)
0.1 0.3 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.1 0.2 GO:2000189 regulation of cholesterol homeostasis(GO:2000188) positive regulation of cholesterol homeostasis(GO:2000189)
0.1 0.2 GO:0048263 determination of dorsal identity(GO:0048263)
0.1 0.2 GO:0007262 STAT protein import into nucleus(GO:0007262) regulation of growth hormone receptor signaling pathway(GO:0060398)
0.1 0.4 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 0.7 GO:0032876 regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.1 0.7 GO:0046718 viral entry into host cell(GO:0046718)
0.1 0.2 GO:0050758 thymidylate synthase biosynthetic process(GO:0050757) regulation of thymidylate synthase biosynthetic process(GO:0050758) negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.1 0.2 GO:0051958 methotrexate transport(GO:0051958)
0.1 0.2 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.1 1.6 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.1 0.4 GO:0031657 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031657) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.1 0.2 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037) actin filament reorganization(GO:0090527)
0.1 0.2 GO:0007518 myoblast fate determination(GO:0007518)
0.1 0.3 GO:0007386 compartment pattern specification(GO:0007386)
0.1 1.1 GO:0030225 macrophage differentiation(GO:0030225)
0.1 0.5 GO:0043545 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0 0.3 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.0 0.4 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.2 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.2 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.1 GO:0021919 BMP signaling pathway involved in spinal cord dorsal/ventral patterning(GO:0021919)
0.0 0.4 GO:0031017 exocrine pancreas development(GO:0031017)
0.0 0.1 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 1.6 GO:0030866 cortical cytoskeleton organization(GO:0030865) cortical actin cytoskeleton organization(GO:0030866)
0.0 0.3 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.0 0.2 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.0 0.1 GO:0043418 cysteine biosynthetic process from serine(GO:0006535) homoserine metabolic process(GO:0009092) cysteine biosynthetic process via cystathionine(GO:0019343) transsulfuration(GO:0019346) homocysteine catabolic process(GO:0043418)
0.0 0.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.3 GO:0043113 receptor clustering(GO:0043113)
0.0 0.1 GO:0010107 potassium ion import(GO:0010107)
0.0 0.3 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.2 GO:0003078 obsolete regulation of natriuresis(GO:0003078)
0.0 0.2 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0 0.2 GO:0021978 telencephalon regionalization(GO:0021978)
0.0 0.3 GO:0015705 iodide transport(GO:0015705)
0.0 0.6 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.1 GO:0072369 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716) regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.0 0.3 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.5 GO:0001885 endothelial cell development(GO:0001885)
0.0 0.1 GO:0007285 primary spermatocyte growth(GO:0007285)
0.0 0.2 GO:0032203 telomere formation via telomerase(GO:0032203)
0.0 1.0 GO:0018208 peptidyl-proline modification(GO:0018208)
0.0 0.1 GO:0000187 activation of MAPK activity(GO:0000187) positive regulation of MAP kinase activity(GO:0043406)
0.0 0.3 GO:0009404 toxin metabolic process(GO:0009404)
0.0 0.1 GO:0000114 obsolete regulation of transcription involved in G1 phase of mitotic cell cycle(GO:0000114)
0.0 0.6 GO:0007281 germ cell development(GO:0007281)
0.0 0.7 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.1 GO:0002385 innate immune response in mucosa(GO:0002227) mucosal immune response(GO:0002385) response to lipid hydroperoxide(GO:0006982)
0.0 1.3 GO:0007224 smoothened signaling pathway(GO:0007224)
0.0 1.0 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 0.2 GO:0030514 regulation of BMP signaling pathway(GO:0030510) negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.3 GO:0033261 obsolete regulation of S phase(GO:0033261)
0.0 0.1 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 1.0 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.1 GO:0002268 follicular dendritic cell activation(GO:0002266) follicular dendritic cell differentiation(GO:0002268)
0.0 0.4 GO:0001893 maternal placenta development(GO:0001893)
0.0 0.2 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.1 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0 0.2 GO:0034331 cell junction maintenance(GO:0034331) cell-cell junction maintenance(GO:0045217)
0.0 0.2 GO:0045329 amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.0 0.7 GO:0016574 histone ubiquitination(GO:0016574)
0.0 0.1 GO:0008228 opsonization(GO:0008228)
0.0 1.3 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.6 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 2.3 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.4 GO:0001709 cell fate determination(GO:0001709)
0.0 0.1 GO:0051383 kinetochore assembly(GO:0051382) kinetochore organization(GO:0051383)
0.0 0.1 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.0 0.1 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.0 0.1 GO:1902692 regulation of neuroblast proliferation(GO:1902692)
0.0 0.2 GO:0032148 activation of protein kinase B activity(GO:0032148)
0.0 0.5 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.2 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.1 GO:0048799 endochondral bone growth(GO:0003416) growth plate cartilage development(GO:0003417) ossification involved in bone maturation(GO:0043931) organ maturation(GO:0048799) bone maturation(GO:0070977) bone growth(GO:0098868)
0.0 0.1 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.0 2.0 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.2 GO:0034447 very-low-density lipoprotein particle clearance(GO:0034447)
0.0 0.9 GO:0060041 retina development in camera-type eye(GO:0060041)
0.0 0.6 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.1 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.1 GO:0035058 nonmotile primary cilium assembly(GO:0035058)
0.0 0.4 GO:1902583 multi-organism transport(GO:0044766) transport of virus(GO:0046794) intracellular transport of virus(GO:0075733) multi-organism localization(GO:1902579) multi-organism intracellular transport(GO:1902583)
0.0 0.3 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.4 GO:0065004 protein-DNA complex assembly(GO:0065004)
0.0 0.1 GO:0044380 protein localization to cytoskeleton(GO:0044380) protein localization to microtubule cytoskeleton(GO:0072698)
0.0 0.2 GO:0009308 amine metabolic process(GO:0009308)
0.0 0.1 GO:0040015 stress granule assembly(GO:0034063) negative regulation of multicellular organism growth(GO:0040015)
0.0 0.1 GO:0060123 regulation of growth hormone secretion(GO:0060123) positive regulation of growth hormone secretion(GO:0060124)
0.0 0.9 GO:0060828 regulation of canonical Wnt signaling pathway(GO:0060828)
0.0 0.1 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.2 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.5 GO:0042472 inner ear morphogenesis(GO:0042472)
0.0 0.2 GO:0014037 Schwann cell differentiation(GO:0014037)
0.0 0.1 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.0 0.2 GO:0045446 endothelium development(GO:0003158) endothelial cell differentiation(GO:0045446)
0.0 0.2 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.4 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 0.2 GO:0050687 negative regulation of defense response to virus(GO:0050687)
0.0 0.1 GO:0007091 metaphase/anaphase transition of mitotic cell cycle(GO:0007091) regulation of mitotic sister chromatid separation(GO:0010965) regulation of mitotic sister chromatid segregation(GO:0033047) metaphase/anaphase transition of cell cycle(GO:0044784) chromosome separation(GO:0051304) mitotic sister chromatid separation(GO:0051306)
0.0 0.1 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.0 0.0 GO:0035283 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.2 GO:0043101 purine-containing compound salvage(GO:0043101)
0.0 0.6 GO:0030183 B cell differentiation(GO:0030183)
0.0 0.4 GO:0050663 cytokine secretion(GO:0050663)
0.0 4.6 GO:0000122 negative regulation of transcription from RNA polymerase II promoter(GO:0000122)
0.0 0.1 GO:0001866 NK T cell proliferation(GO:0001866)
0.0 0.8 GO:1903037 regulation of T cell activation(GO:0050863) regulation of leukocyte cell-cell adhesion(GO:1903037)
0.0 0.1 GO:0007140 male meiosis(GO:0007140)
0.0 0.1 GO:0098762 meiotic prophase I(GO:0007128) meiotic cell cycle phase(GO:0098762) meiosis I cell cycle phase(GO:0098764)
0.0 0.0 GO:0051593 response to folic acid(GO:0051593)
0.0 0.2 GO:0031055 DNA replication-independent nucleosome assembly(GO:0006336) chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) centromere complex assembly(GO:0034508) DNA replication-independent nucleosome organization(GO:0034724) CENP-A containing chromatin organization(GO:0061641)
0.0 0.1 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.1 GO:0043010 camera-type eye development(GO:0043010)
0.0 0.3 GO:0009187 cyclic nucleotide metabolic process(GO:0009187)
0.0 0.1 GO:2000124 cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926) regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.1 GO:0043278 response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.0 0.1 GO:0018101 protein citrullination(GO:0018101)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.2 1.9 GO:0016012 sarcoglycan complex(GO:0016012)
0.2 1.4 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369) beta-catenin-TCF complex(GO:1990907)
0.2 3.2 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2 0.7 GO:0005726 perichromatin fibrils(GO:0005726)
0.2 0.8 GO:0032133 chromosome passenger complex(GO:0032133)
0.1 1.0 GO:0001739 sex chromatin(GO:0001739)
0.1 1.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 1.0 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 0.6 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 1.4 GO:0071564 npBAF complex(GO:0071564)
0.1 0.5 GO:0008278 cohesin complex(GO:0008278)
0.1 0.7 GO:0032039 integrator complex(GO:0032039)
0.1 0.3 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.1 0.7 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 0.5 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 0.5 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.4 GO:0010369 chromocenter(GO:0010369)
0.0 0.6 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.1 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.0 0.1 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 0.5 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 0.1 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 0.1 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.2 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.1 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.3 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.5 GO:0001772 immunological synapse(GO:0001772)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 0.1 GO:0030914 STAGA complex(GO:0030914)
0.0 0.2 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.6 GO:0030530 obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0 1.0 GO:0015030 Cajal body(GO:0015030)
0.0 2.8 GO:0019898 extrinsic component of membrane(GO:0019898)
0.0 0.7 GO:0032432 actin filament bundle(GO:0032432)
0.0 0.9 GO:0005884 actin filament(GO:0005884)
0.0 1.2 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.2 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.1 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.3 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.3 GO:0090568 NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.1 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.4 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.1 GO:1903561 extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0 0.1 GO:0042597 NMDA selective glutamate receptor complex(GO:0017146) outer membrane-bounded periplasmic space(GO:0030288) periplasmic space(GO:0042597)
0.0 0.7 GO:0055037 recycling endosome(GO:0055037)
0.0 1.0 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.4 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.2 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.9 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.3 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 1.1 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 1.7 GO:0009897 external side of plasma membrane(GO:0009897)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.3 1.3 GO:0034711 inhibin binding(GO:0034711)
0.2 0.6 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.2 0.7 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.2 0.7 GO:0050833 pyruvate secondary active transmembrane transporter activity(GO:0005477) pyruvate transmembrane transporter activity(GO:0050833)
0.2 1.0 GO:0042577 lipid phosphatase activity(GO:0042577)
0.2 0.5 GO:0052593 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.2 1.3 GO:0008158 hedgehog receptor activity(GO:0008158)
0.2 0.6 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.1 0.4 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.1 0.6 GO:0034190 apolipoprotein receptor binding(GO:0034190) high-density lipoprotein particle receptor binding(GO:0070653)
0.1 0.7 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1 2.3 GO:0005522 profilin binding(GO:0005522)
0.1 0.9 GO:0001515 opioid peptide activity(GO:0001515)
0.1 0.6 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.1 0.8 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.1 0.3 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.3 GO:0005224 ATP-binding and phosphorylation-dependent chloride channel activity(GO:0005224) channel-conductance-controlling ATPase activity(GO:0005260)
0.1 1.7 GO:0030332 cyclin binding(GO:0030332)
0.1 1.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 0.3 GO:0050692 DBD domain binding(GO:0050692)
0.1 0.7 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.1 0.3 GO:0016841 ammonia-lyase activity(GO:0016841)
0.1 1.1 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.1 0.9 GO:0031701 angiotensin receptor binding(GO:0031701)
0.1 0.7 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.1 2.1 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 0.3 GO:0000739 obsolete DNA strand annealing activity(GO:0000739)
0.1 3.2 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 0.2 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.1 0.2 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.1 0.3 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.1 0.1 GO:0005113 patched binding(GO:0005113)
0.1 0.7 GO:0034056 estrogen response element binding(GO:0034056)
0.1 0.4 GO:0001968 fibronectin binding(GO:0001968)
0.1 0.6 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.3 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 0.4 GO:0051766 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.1 0.2 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.1 0.2 GO:0032810 sterol response element binding(GO:0032810)
0.1 4.4 GO:0003697 single-stranded DNA binding(GO:0003697)
0.1 0.2 GO:0015350 methotrexate transporter activity(GO:0015350)
0.1 0.2 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1 5.9 GO:0003704 obsolete specific RNA polymerase II transcription factor activity(GO:0003704)
0.1 0.3 GO:0032190 acrosin binding(GO:0032190)
0.1 0.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.2 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.0 1.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.5 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.2 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.1 GO:0004122 cystathionine beta-synthase activity(GO:0004122)
0.0 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.3 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.2 GO:0033981 D-dopachrome decarboxylase activity(GO:0033981)
0.0 0.6 GO:0003840 gamma-glutamyltransferase activity(GO:0003840)
0.0 1.0 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.4 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.3 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.2 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.6 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.9 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 1.0 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 1.5 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.0 0.5 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.2 GO:0042156 obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0 0.2 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.2 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.2 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.4 GO:0001619 obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619)
0.0 2.7 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.2 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.1 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.3 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.5 GO:0043498 obsolete cell surface binding(GO:0043498)
0.0 0.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.1 GO:0045296 cadherin binding(GO:0045296)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.3 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.0 0.2 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.2 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0010698 angiotensin type I receptor activity(GO:0001596) acetyltransferase activator activity(GO:0010698)
0.0 0.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.2 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.7 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.2 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.2 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 3.9 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.3 GO:0030553 cGMP binding(GO:0030553)
0.0 0.4 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.1 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 0.5 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.5 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.5 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.4 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.7 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.7 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0 0.1 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.4 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 1.0 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.1 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.4 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 0.1 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0 0.2 GO:0005521 lamin binding(GO:0005521)
0.0 2.7 GO:0003682 chromatin binding(GO:0003682)
0.0 2.0 GO:0010843 obsolete promoter binding(GO:0010843)
0.0 0.2 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.3 GO:0003690 double-stranded DNA binding(GO:0003690)
0.0 0.1 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0005497 androgen binding(GO:0005497)
0.0 0.8 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.2 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 2.4 GO:0008083 growth factor activity(GO:0008083)
0.0 0.8 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 1.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.2 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 2.8 GO:0005096 GTPase activator activity(GO:0005096)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 ST_B_CELL_ANTIGEN_RECEPTOR B Cell Antigen Receptor
0.0 4.0 ST_T_CELL_SIGNAL_TRANSDUCTION T Cell Signal Transduction
0.0 0.2 ST_IL_13_PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.6 ST_GRANULE_CELL_SURVIVAL_PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.4 ST_G_ALPHA_I_PATHWAY G alpha i Pathway
0.0 1.1 ST_P38_MAPK_PATHWAY p38 MAPK Pathway