Motif ID: NFATC2_NFATC3
Z-value: 3.020
Transcription factors associated with NFATC2_NFATC3:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| NFATC2 | ENSG00000101096.15 | NFATC2 |
| NFATC3 | ENSG00000072736.14 | NFATC3 |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.9 | 11.7 | GO:2000121 | regulation of removal of superoxide radicals(GO:2000121) |
| 2.7 | 10.7 | GO:0010716 | regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054) |
| 2.1 | 23.0 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
| 1.5 | 11.9 | GO:0003065 | regulation of heart rate by chemical signal(GO:0003062) positive regulation of heart rate by epinephrine(GO:0003065) |
| 1.3 | 3.9 | GO:0008218 | bioluminescence(GO:0008218) |
| 1.2 | 7.1 | GO:0060710 | chorio-allantoic fusion(GO:0060710) |
| 1.0 | 6.3 | GO:0006196 | AMP catabolic process(GO:0006196) |
| 1.0 | 1.9 | GO:0035120 | post-embryonic appendage morphogenesis(GO:0035120) |
| 0.9 | 2.7 | GO:0070092 | regulation of glucagon secretion(GO:0070092) |
| 0.9 | 5.2 | GO:0060242 | contact inhibition(GO:0060242) |
| 0.9 | 3.4 | GO:0042268 | regulation of cytolysis(GO:0042268) |
| 0.8 | 2.5 | GO:0060596 | mammary placode formation(GO:0060596) |
| 0.8 | 2.4 | GO:0060279 | progesterone secretion(GO:0042701) regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279) |
| 0.8 | 2.3 | GO:0043371 | negative regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043371) negative regulation of T-helper cell differentiation(GO:0045623) negative regulation of CD4-positive, alpha-beta T cell activation(GO:2000515) |
| 0.7 | 2.6 | GO:0009956 | radial pattern formation(GO:0009956) |
| 0.7 | 3.9 | GO:0060219 | camera-type eye photoreceptor cell differentiation(GO:0060219) |
| 0.6 | 0.6 | GO:0070091 | glucagon secretion(GO:0070091) |
| 0.5 | 5.7 | GO:0051497 | negative regulation of stress fiber assembly(GO:0051497) |
| 0.5 | 1.5 | GO:0010273 | detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169) |
| 0.5 | 1.5 | GO:0007412 | axon target recognition(GO:0007412) |
| 0.5 | 1.4 | GO:0043006 | activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006) |
| 0.4 | 6.1 | GO:0031529 | ruffle organization(GO:0031529) |
| 0.4 | 4.3 | GO:0040037 | negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037) |
| 0.4 | 2.9 | GO:0030579 | ubiquitin-dependent SMAD protein catabolic process(GO:0030579) |
| 0.4 | 1.2 | GO:0014889 | muscle atrophy(GO:0014889) regulation of skeletal muscle tissue growth(GO:0048631) |
| 0.4 | 1.9 | GO:0001553 | luteinization(GO:0001553) |
| 0.4 | 2.6 | GO:0060414 | aorta development(GO:0035904) aorta morphogenesis(GO:0035909) aorta smooth muscle tissue morphogenesis(GO:0060414) |
| 0.4 | 1.4 | GO:0045112 | integrin biosynthetic process(GO:0045112) |
| 0.3 | 2.0 | GO:0045916 | negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258) |
| 0.3 | 3.4 | GO:0051014 | actin filament severing(GO:0051014) |
| 0.3 | 1.0 | GO:0021570 | rhombomere 4 development(GO:0021570) |
| 0.3 | 7.5 | GO:0030199 | collagen fibril organization(GO:0030199) |
| 0.3 | 0.9 | GO:0070886 | positive regulation of calcineurin-NFAT signaling cascade(GO:0070886) |
| 0.3 | 1.1 | GO:0071418 | uroporphyrinogen III biosynthetic process(GO:0006780) cellular response to amine stimulus(GO:0071418) |
| 0.3 | 0.3 | GO:2000794 | positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000794) |
| 0.3 | 2.8 | GO:0010739 | positive regulation of protein kinase A signaling(GO:0010739) |
| 0.3 | 7.3 | GO:0043462 | regulation of ATPase activity(GO:0043462) |
| 0.2 | 1.0 | GO:0048619 | embryonic hindgut morphogenesis(GO:0048619) |
| 0.2 | 1.2 | GO:0009756 | carbohydrate mediated signaling(GO:0009756) |
| 0.2 | 1.2 | GO:0008049 | male courtship behavior(GO:0008049) |
| 0.2 | 1.2 | GO:0018345 | protein palmitoylation(GO:0018345) |
| 0.2 | 1.2 | GO:0006880 | intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577) |
| 0.2 | 1.0 | GO:0032472 | cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) Golgi calcium ion transport(GO:0032472) manganese ion homeostasis(GO:0055071) |
| 0.2 | 1.0 | GO:0001514 | selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451) |
| 0.2 | 3.1 | GO:0032012 | regulation of ARF protein signal transduction(GO:0032012) |
| 0.2 | 0.8 | GO:0090050 | positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672) |
| 0.1 | 0.4 | GO:0071460 | cellular response to cell-matrix adhesion(GO:0071460) |
| 0.1 | 0.3 | GO:0060298 | negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771) positive regulation of sarcomere organization(GO:0060298) |
| 0.1 | 2.5 | GO:0035115 | embryonic forelimb morphogenesis(GO:0035115) |
| 0.1 | 1.9 | GO:0046697 | decidualization(GO:0046697) |
| 0.1 | 1.1 | GO:0010799 | regulation of peptidyl-threonine phosphorylation(GO:0010799) positive regulation of peptidyl-threonine phosphorylation(GO:0010800) |
| 0.1 | 6.2 | GO:0090263 | positive regulation of canonical Wnt signaling pathway(GO:0090263) |
| 0.1 | 7.0 | GO:0001837 | epithelial to mesenchymal transition(GO:0001837) |
| 0.1 | 1.0 | GO:0010871 | negative regulation of receptor biosynthetic process(GO:0010871) |
| 0.1 | 5.0 | GO:0030520 | intracellular estrogen receptor signaling pathway(GO:0030520) |
| 0.1 | 1.1 | GO:0035434 | copper ion transmembrane transport(GO:0035434) |
| 0.1 | 0.7 | GO:0046541 | saliva secretion(GO:0046541) |
| 0.1 | 0.4 | GO:0007221 | positive regulation of transcription of Notch receptor target(GO:0007221) |
| 0.1 | 0.2 | GO:0090047 | retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299) obsolete positive regulation of transcription regulator activity(GO:0090047) |
| 0.1 | 0.7 | GO:0006295 | nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295) |
| 0.1 | 1.0 | GO:0034638 | phosphatidylcholine catabolic process(GO:0034638) |
| 0.1 | 0.2 | GO:0050908 | detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962) |
| 0.1 | 0.3 | GO:0006041 | glucosamine metabolic process(GO:0006041) |
| 0.1 | 0.6 | GO:0051708 | intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708) |
| 0.1 | 1.1 | GO:0050435 | beta-amyloid metabolic process(GO:0050435) |
| 0.1 | 0.5 | GO:0070050 | neuron cellular homeostasis(GO:0070050) |
| 0.1 | 0.5 | GO:0090084 | negative regulation of inclusion body assembly(GO:0090084) |
| 0.1 | 1.0 | GO:0070670 | response to interleukin-4(GO:0070670) |
| 0.1 | 1.2 | GO:0033687 | osteoblast proliferation(GO:0033687) |
| 0.1 | 0.5 | GO:0051024 | positive regulation of immunoglobulin secretion(GO:0051024) |
| 0.1 | 0.4 | GO:0032431 | activation of phospholipase A2 activity(GO:0032431) |
| 0.1 | 0.1 | GO:0060157 | urinary bladder development(GO:0060157) |
| 0.1 | 0.5 | GO:0060052 | neurofilament cytoskeleton organization(GO:0060052) |
| 0.1 | 1.1 | GO:1901797 | negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797) |
| 0.1 | 0.2 | GO:0032430 | positive regulation of phospholipase A2 activity(GO:0032430) |
| 0.1 | 0.9 | GO:0019885 | antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885) |
| 0.1 | 0.1 | GO:0071639 | monocyte chemotactic protein-1 production(GO:0071605) regulation of monocyte chemotactic protein-1 production(GO:0071637) positive regulation of monocyte chemotactic protein-1 production(GO:0071639) |
| 0.1 | 2.1 | GO:0050873 | brown fat cell differentiation(GO:0050873) |
| 0.1 | 1.3 | GO:0045749 | obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749) |
| 0.1 | 0.1 | GO:0002088 | lens development in camera-type eye(GO:0002088) |
| 0.1 | 0.2 | GO:0002575 | basophil chemotaxis(GO:0002575) |
| 0.1 | 0.3 | GO:0060174 | limb bud formation(GO:0060174) |
| 0.1 | 0.2 | GO:0033860 | regulation of NAD(P)H oxidase activity(GO:0033860) |
| 0.1 | 0.2 | GO:0071635 | negative regulation of transforming growth factor beta production(GO:0071635) |
| 0.1 | 0.2 | GO:0045109 | intermediate filament organization(GO:0045109) |
| 0.1 | 1.2 | GO:0010811 | positive regulation of cell-substrate adhesion(GO:0010811) |
| 0.1 | 2.2 | GO:0007190 | activation of adenylate cyclase activity(GO:0007190) |
| 0.1 | 4.3 | GO:0030198 | extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062) |
| 0.1 | 1.3 | GO:0006911 | phagocytosis, engulfment(GO:0006911) membrane invagination(GO:0010324) |
| 0.1 | 1.3 | GO:0017158 | regulation of calcium ion-dependent exocytosis(GO:0017158) |
| 0.1 | 0.4 | GO:0045116 | protein neddylation(GO:0045116) |
| 0.1 | 1.6 | GO:0016486 | peptide hormone processing(GO:0016486) |
| 0.1 | 0.5 | GO:0007217 | tachykinin receptor signaling pathway(GO:0007217) |
| 0.0 | 0.1 | GO:0071801 | podosome assembly(GO:0071800) regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803) |
| 0.0 | 1.1 | GO:0007528 | neuromuscular junction development(GO:0007528) |
| 0.0 | 0.8 | GO:0050812 | acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812) |
| 0.0 | 3.1 | GO:0043542 | endothelial cell migration(GO:0043542) |
| 0.0 | 0.2 | GO:0002467 | germinal center formation(GO:0002467) |
| 0.0 | 0.7 | GO:1901661 | quinone metabolic process(GO:1901661) |
| 0.0 | 3.4 | GO:0007229 | integrin-mediated signaling pathway(GO:0007229) |
| 0.0 | 0.3 | GO:0046856 | phosphatidylinositol dephosphorylation(GO:0046856) |
| 0.0 | 1.1 | GO:0030866 | cortical actin cytoskeleton organization(GO:0030866) |
| 0.0 | 0.5 | GO:0097031 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
| 0.0 | 0.1 | GO:0009301 | snRNA transcription(GO:0009301) |
| 0.0 | 1.4 | GO:0007026 | negative regulation of microtubule depolymerization(GO:0007026) |
| 0.0 | 0.4 | GO:0007168 | receptor guanylyl cyclase signaling pathway(GO:0007168) |
| 0.0 | 8.3 | GO:0007517 | muscle organ development(GO:0007517) |
| 0.0 | 1.0 | GO:0034199 | activation of protein kinase A activity(GO:0034199) |
| 0.0 | 0.3 | GO:0090292 | nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292) |
| 0.0 | 0.6 | GO:0002675 | positive regulation of acute inflammatory response(GO:0002675) |
| 0.0 | 0.2 | GO:0048537 | mucosal-associated lymphoid tissue development(GO:0048537) |
| 0.0 | 0.7 | GO:0036075 | endochondral ossification(GO:0001958) replacement ossification(GO:0036075) |
| 0.0 | 1.8 | GO:0007338 | single fertilization(GO:0007338) |
| 0.0 | 0.6 | GO:0031032 | actomyosin structure organization(GO:0031032) |
| 0.0 | 0.2 | GO:0032753 | positive regulation of interleukin-4 production(GO:0032753) |
| 0.0 | 0.1 | GO:0002828 | regulation of type 2 immune response(GO:0002828) |
| 0.0 | 1.3 | GO:0007193 | adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193) |
| 0.0 | 7.2 | GO:0006936 | muscle contraction(GO:0006936) |
| 0.0 | 0.7 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
| 0.0 | 1.5 | GO:0006749 | glutathione metabolic process(GO:0006749) |
| 0.0 | 0.2 | GO:0002011 | morphogenesis of an epithelial sheet(GO:0002011) |
| 0.0 | 0.4 | GO:0048207 | vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114) |
| 0.0 | 0.1 | GO:0035520 | monoubiquitinated protein deubiquitination(GO:0035520) |
| 0.0 | 0.7 | GO:0050909 | sensory perception of taste(GO:0050909) |
| 0.0 | 0.1 | GO:0017014 | protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119) |
| 0.0 | 2.2 | GO:0002756 | MyD88-independent toll-like receptor signaling pathway(GO:0002756) |
| 0.0 | 0.4 | GO:0021846 | cell proliferation in forebrain(GO:0021846) |
| 0.0 | 0.2 | GO:0015810 | C4-dicarboxylate transport(GO:0015740) aspartate transport(GO:0015810) |
| 0.0 | 1.7 | GO:0006986 | response to unfolded protein(GO:0006986) |
| 0.0 | 1.0 | GO:0042476 | odontogenesis(GO:0042476) |
| 0.0 | 0.6 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
| 0.0 | 0.5 | GO:0006662 | glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904) |
| 0.0 | 0.6 | GO:0008038 | neuron recognition(GO:0008038) |
| 0.0 | 0.4 | GO:0042359 | vitamin D metabolic process(GO:0042359) |
| 0.0 | 0.1 | GO:0048546 | digestive tract morphogenesis(GO:0048546) |
| 0.0 | 1.3 | GO:0007218 | neuropeptide signaling pathway(GO:0007218) |
| 0.0 | 0.2 | GO:0050718 | interleukin-1 beta secretion(GO:0050702) regulation of interleukin-1 beta secretion(GO:0050706) positive regulation of interleukin-1 beta secretion(GO:0050718) |
| 0.0 | 0.1 | GO:0015910 | peroxisomal long-chain fatty acid import(GO:0015910) |
| 0.0 | 0.9 | GO:0051084 | 'de novo' posttranslational protein folding(GO:0051084) |
| 0.0 | 0.4 | GO:0007368 | determination of left/right symmetry(GO:0007368) |
| 0.0 | 0.1 | GO:0009396 | folic acid-containing compound biosynthetic process(GO:0009396) |
| 0.0 | 0.7 | GO:0045454 | cell redox homeostasis(GO:0045454) |
| 0.0 | 0.1 | GO:0032776 | DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116) |
| 0.0 | 0.4 | GO:0050931 | melanocyte differentiation(GO:0030318) pigment cell differentiation(GO:0050931) |
| 0.0 | 0.3 | GO:0007263 | nitric oxide mediated signal transduction(GO:0007263) |
| 0.0 | 0.3 | GO:0045669 | positive regulation of osteoblast differentiation(GO:0045669) |
| 0.0 | 0.1 | GO:0045059 | positive thymic T cell selection(GO:0045059) |
| 0.0 | 0.2 | GO:0043508 | negative regulation of JUN kinase activity(GO:0043508) |
| 0.0 | 0.1 | GO:0006772 | thiamine metabolic process(GO:0006772) |
| 0.0 | 4.1 | GO:0051056 | regulation of small GTPase mediated signal transduction(GO:0051056) |
| 0.0 | 1.6 | GO:0006814 | sodium ion transport(GO:0006814) |
| 0.0 | 0.1 | GO:0006084 | acetyl-CoA metabolic process(GO:0006084) |
| 0.0 | 0.0 | GO:0034390 | smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391) |
| 0.0 | 0.1 | GO:0009249 | protein lipoylation(GO:0009249) |
| 0.0 | 0.8 | GO:0006754 | ATP biosynthetic process(GO:0006754) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.9 | 11.7 | GO:0071953 | elastic fiber(GO:0071953) |
| 3.3 | 9.8 | GO:0005588 | collagen type V trimer(GO:0005588) |
| 2.7 | 37.3 | GO:0098647 | collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647) |
| 2.1 | 10.7 | GO:0071438 | invadopodium membrane(GO:0071438) |
| 1.0 | 19.6 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
| 0.8 | 2.4 | GO:0043512 | inhibin complex(GO:0043511) inhibin A complex(GO:0043512) |
| 0.8 | 3.8 | GO:0060171 | stereocilium membrane(GO:0060171) |
| 0.6 | 3.9 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
| 0.6 | 2.8 | GO:0005899 | insulin receptor complex(GO:0005899) |
| 0.3 | 1.2 | GO:0070288 | intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288) |
| 0.3 | 1.3 | GO:0060201 | clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201) |
| 0.2 | 12.2 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
| 0.2 | 1.4 | GO:0070435 | Shc-EGFR complex(GO:0070435) |
| 0.2 | 1.7 | GO:0005593 | FACIT collagen trimer(GO:0005593) |
| 0.2 | 0.6 | GO:0005900 | oncostatin-M receptor complex(GO:0005900) |
| 0.2 | 0.6 | GO:0005896 | interleukin-6 receptor complex(GO:0005896) |
| 0.2 | 1.5 | GO:0016012 | sarcoglycan complex(GO:0016012) |
| 0.2 | 0.7 | GO:0030936 | collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936) |
| 0.2 | 3.5 | GO:0016010 | dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665) |
| 0.2 | 2.5 | GO:0005606 | laminin-1 complex(GO:0005606) |
| 0.2 | 1.0 | GO:0070369 | beta-catenin-TCF7L2 complex(GO:0070369) beta-catenin-TCF complex(GO:1990907) |
| 0.1 | 1.3 | GO:0098645 | network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) |
| 0.1 | 1.7 | GO:0005858 | axonemal dynein complex(GO:0005858) axoneme part(GO:0044447) |
| 0.1 | 0.6 | GO:0043235 | receptor complex(GO:0043235) |
| 0.1 | 1.9 | GO:0008091 | spectrin(GO:0008091) |
| 0.1 | 1.1 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
| 0.1 | 0.2 | GO:0031904 | endosome lumen(GO:0031904) |
| 0.1 | 2.9 | GO:0030286 | dynein complex(GO:0030286) |
| 0.1 | 1.1 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.1 | 0.7 | GO:0098643 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
| 0.1 | 3.8 | GO:0005604 | basement membrane(GO:0005604) |
| 0.1 | 0.5 | GO:0005883 | neurofilament(GO:0005883) |
| 0.1 | 0.3 | GO:0070826 | paraferritin complex(GO:0070826) |
| 0.1 | 0.7 | GO:0000109 | nucleotide-excision repair complex(GO:0000109) |
| 0.1 | 0.2 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
| 0.1 | 0.2 | GO:0038201 | TORC2 complex(GO:0031932) TOR complex(GO:0038201) |
| 0.1 | 9.9 | GO:0005925 | focal adhesion(GO:0005925) |
| 0.0 | 6.8 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.0 | 2.2 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.0 | 1.4 | GO:0005776 | autophagosome(GO:0005776) |
| 0.0 | 0.3 | GO:0034993 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
| 0.0 | 1.4 | GO:0098636 | integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636) |
| 0.0 | 0.4 | GO:0043202 | lysosomal lumen(GO:0043202) |
| 0.0 | 0.7 | GO:0030134 | ER to Golgi transport vesicle(GO:0030134) |
| 0.0 | 0.1 | GO:0043195 | terminal bouton(GO:0043195) |
| 0.0 | 2.0 | GO:0005802 | trans-Golgi network(GO:0005802) |
| 0.0 | 0.9 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 0.0 | 0.7 | GO:0042612 | MHC class I protein complex(GO:0042612) |
| 0.0 | 0.2 | GO:0042105 | alpha-beta T cell receptor complex(GO:0042105) |
| 0.0 | 0.3 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 0.0 | 4.1 | GO:0005795 | Golgi stack(GO:0005795) |
| 0.0 | 0.3 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
| 0.0 | 1.7 | GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment(GO:0005793) |
| 0.0 | 0.6 | GO:0031594 | neuromuscular junction(GO:0031594) |
| 0.0 | 6.1 | GO:0016324 | apical plasma membrane(GO:0016324) |
| 0.0 | 0.1 | GO:0017119 | Golgi transport complex(GO:0017119) |
| 0.0 | 0.8 | GO:0036064 | ciliary basal body(GO:0036064) |
| 0.0 | 0.1 | GO:0071437 | invadopodium(GO:0071437) |
| 0.0 | 1.6 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 0.0 | 4.7 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.0 | 1.6 | GO:0009898 | cytoplasmic side of plasma membrane(GO:0009898) cytoplasmic side of membrane(GO:0098562) |
| 0.0 | 0.5 | GO:0005811 | lipid particle(GO:0005811) |
| 0.0 | 0.5 | GO:0016234 | inclusion body(GO:0016234) |
| 0.0 | 0.7 | GO:0005637 | nuclear inner membrane(GO:0005637) |
| 0.0 | 0.2 | GO:0031105 | septin complex(GO:0031105) septin cytoskeleton(GO:0032156) |
| 0.0 | 0.2 | GO:0031902 | late endosome membrane(GO:0031902) |
| 0.0 | 0.3 | GO:0043073 | germ cell nucleus(GO:0043073) |
| 0.0 | 0.6 | GO:0045095 | keratin filament(GO:0045095) |
| 0.0 | 1.1 | GO:0030496 | midbody(GO:0030496) |
| 0.0 | 0.0 | GO:0005850 | eukaryotic translation initiation factor 2 complex(GO:0005850) |
| 0.0 | 0.9 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.0 | 0.1 | GO:0030897 | HOPS complex(GO:0030897) |
| 0.0 | 0.6 | GO:0030964 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 2.8 | GO:0005010 | insulin-like growth factor-activated receptor activity(GO:0005010) |
| 0.9 | 6.3 | GO:0008253 | 5'-nucleotidase activity(GO:0008253) |
| 0.9 | 35.6 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.8 | 2.4 | GO:0048184 | obsolete follistatin binding(GO:0048184) |
| 0.8 | 3.9 | GO:0034235 | GPI anchor binding(GO:0034235) |
| 0.7 | 2.0 | GO:0019958 | C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959) |
| 0.6 | 1.9 | GO:0005017 | platelet-derived growth factor-activated receptor activity(GO:0005017) |
| 0.6 | 3.6 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
| 0.6 | 10.7 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
| 0.6 | 1.8 | GO:0016524 | latrotoxin receptor activity(GO:0016524) |
| 0.5 | 2.6 | GO:0004687 | myosin light chain kinase activity(GO:0004687) |
| 0.5 | 1.4 | GO:0032422 | purine-rich negative regulatory element binding(GO:0032422) |
| 0.5 | 2.8 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.4 | 7.0 | GO:0050786 | RAGE receptor binding(GO:0050786) |
| 0.4 | 6.1 | GO:0004065 | arylsulfatase activity(GO:0004065) |
| 0.4 | 2.9 | GO:0048495 | Roundabout binding(GO:0048495) |
| 0.4 | 5.7 | GO:0043274 | phospholipase binding(GO:0043274) |
| 0.4 | 6.1 | GO:0003785 | actin monomer binding(GO:0003785) |
| 0.4 | 2.8 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
| 0.3 | 1.6 | GO:0034597 | phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) phosphatidylinositol phosphate 4-phosphatase activity(GO:0034596) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) |
| 0.3 | 1.0 | GO:0047391 | alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391) |
| 0.3 | 0.6 | GO:0019956 | chemokine binding(GO:0019956) |
| 0.3 | 1.5 | GO:0031694 | alpha-2A adrenergic receptor binding(GO:0031694) |
| 0.3 | 1.1 | GO:0004852 | uroporphyrinogen-III synthase activity(GO:0004852) |
| 0.3 | 0.8 | GO:0000150 | recombinase activity(GO:0000150) |
| 0.3 | 1.9 | GO:0042731 | PH domain binding(GO:0042731) |
| 0.2 | 1.5 | GO:0031821 | G-protein coupled serotonin receptor binding(GO:0031821) |
| 0.2 | 1.2 | GO:0005534 | galactose binding(GO:0005534) |
| 0.2 | 5.2 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.2 | 1.2 | GO:0016724 | ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724) |
| 0.2 | 19.5 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 0.2 | 1.4 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
| 0.2 | 0.6 | GO:0004924 | oncostatin-M receptor activity(GO:0004924) |
| 0.2 | 8.1 | GO:0005518 | collagen binding(GO:0005518) |
| 0.2 | 2.6 | GO:0016918 | retinal binding(GO:0016918) |
| 0.2 | 2.6 | GO:0003706 | obsolete ligand-regulated transcription factor activity(GO:0003706) |
| 0.2 | 1.3 | GO:0030021 | extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345) |
| 0.2 | 2.1 | GO:0004862 | cAMP-dependent protein kinase inhibitor activity(GO:0004862) |
| 0.2 | 1.0 | GO:0015410 | manganese-transporting ATPase activity(GO:0015410) |
| 0.2 | 0.5 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
| 0.2 | 1.4 | GO:0005006 | epidermal growth factor-activated receptor activity(GO:0005006) |
| 0.2 | 0.9 | GO:0043208 | glycosphingolipid binding(GO:0043208) |
| 0.2 | 0.8 | GO:0004741 | magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724) [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741) |
| 0.2 | 1.4 | GO:0050811 | GABA receptor binding(GO:0050811) |
| 0.1 | 3.1 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.1 | 12.5 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.1 | 0.7 | GO:0004090 | carbonyl reductase (NADPH) activity(GO:0004090) |
| 0.1 | 13.8 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.1 | 3.5 | GO:0008430 | selenium binding(GO:0008430) |
| 0.1 | 3.8 | GO:0005523 | tropomyosin binding(GO:0005523) |
| 0.1 | 11.8 | GO:0005178 | integrin binding(GO:0005178) |
| 0.1 | 0.7 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
| 0.1 | 0.9 | GO:0004563 | beta-N-acetylhexosaminidase activity(GO:0004563) |
| 0.1 | 1.1 | GO:0005375 | copper ion transmembrane transporter activity(GO:0005375) |
| 0.1 | 2.2 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
| 0.1 | 0.7 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
| 0.1 | 0.6 | GO:0005138 | interleukin-6 receptor binding(GO:0005138) |
| 0.1 | 1.1 | GO:0008242 | omega peptidase activity(GO:0008242) |
| 0.1 | 0.5 | GO:0017162 | aryl hydrocarbon receptor binding(GO:0017162) |
| 0.1 | 0.3 | GO:0097642 | calcitonin family receptor activity(GO:0097642) |
| 0.1 | 0.5 | GO:0004703 | G-protein coupled receptor kinase activity(GO:0004703) |
| 0.1 | 3.2 | GO:0051219 | phosphoprotein binding(GO:0051219) |
| 0.1 | 1.0 | GO:0050750 | low-density lipoprotein particle receptor binding(GO:0050750) |
| 0.1 | 0.2 | GO:0010698 | angiotensin type I receptor activity(GO:0001596) acetyltransferase activator activity(GO:0010698) |
| 0.1 | 0.3 | GO:0004882 | androgen receptor activity(GO:0004882) |
| 0.1 | 5.0 | GO:0003697 | single-stranded DNA binding(GO:0003697) |
| 0.1 | 1.0 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.1 | 1.3 | GO:0001540 | beta-amyloid binding(GO:0001540) |
| 0.1 | 0.1 | GO:0005324 | long-chain fatty acid transporter activity(GO:0005324) |
| 0.1 | 0.3 | GO:0005111 | type 2 fibroblast growth factor receptor binding(GO:0005111) |
| 0.1 | 0.4 | GO:0016941 | natriuretic peptide receptor activity(GO:0016941) |
| 0.1 | 0.5 | GO:0004957 | prostaglandin E receptor activity(GO:0004957) |
| 0.1 | 2.1 | GO:0019003 | GDP binding(GO:0019003) |
| 0.1 | 1.0 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
| 0.1 | 0.4 | GO:0004955 | prostaglandin receptor activity(GO:0004955) |
| 0.1 | 0.2 | GO:0015183 | L-aspartate transmembrane transporter activity(GO:0015183) |
| 0.1 | 0.5 | GO:0004415 | hyalurononglucosaminidase activity(GO:0004415) |
| 0.1 | 0.6 | GO:0030274 | LIM domain binding(GO:0030274) |
| 0.1 | 0.3 | GO:0031708 | bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708) |
| 0.1 | 8.4 | GO:0003774 | motor activity(GO:0003774) |
| 0.1 | 1.0 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 0.1 | 0.3 | GO:0004614 | phosphoglucomutase activity(GO:0004614) |
| 0.0 | 0.5 | GO:0008527 | taste receptor activity(GO:0008527) |
| 0.0 | 0.2 | GO:0005078 | MAP-kinase scaffold activity(GO:0005078) |
| 0.0 | 0.5 | GO:0042166 | acetylcholine binding(GO:0042166) |
| 0.0 | 0.4 | GO:0004522 | ribonuclease A activity(GO:0004522) |
| 0.0 | 0.2 | GO:0042608 | T cell receptor binding(GO:0042608) |
| 0.0 | 1.5 | GO:0015035 | protein disulfide oxidoreductase activity(GO:0015035) |
| 0.0 | 1.5 | GO:0004364 | glutathione transferase activity(GO:0004364) |
| 0.0 | 0.4 | GO:0070008 | serine-type exopeptidase activity(GO:0070008) |
| 0.0 | 0.1 | GO:0005222 | intracellular cAMP activated cation channel activity(GO:0005222) |
| 0.0 | 0.2 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
| 0.0 | 0.3 | GO:0004439 | phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439) |
| 0.0 | 0.2 | GO:0005112 | Notch binding(GO:0005112) |
| 0.0 | 0.1 | GO:0005137 | interleukin-5 receptor binding(GO:0005137) |
| 0.0 | 0.9 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.0 | 0.2 | GO:0042834 | peptidoglycan binding(GO:0042834) |
| 0.0 | 0.2 | GO:0008321 | Ral guanyl-nucleotide exchange factor activity(GO:0008321) |
| 0.0 | 0.1 | GO:0008184 | glycogen phosphorylase activity(GO:0008184) |
| 0.0 | 2.6 | GO:0004197 | cysteine-type endopeptidase activity(GO:0004197) |
| 0.0 | 0.9 | GO:0004385 | guanylate kinase activity(GO:0004385) |
| 0.0 | 0.1 | GO:0003989 | acetyl-CoA carboxylase activity(GO:0003989) |
| 0.0 | 0.3 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
| 0.0 | 4.3 | GO:0004386 | helicase activity(GO:0004386) |
| 0.0 | 0.6 | GO:0030159 | receptor signaling complex scaffold activity(GO:0030159) |
| 0.0 | 0.3 | GO:0003709 | obsolete RNA polymerase III transcription factor activity(GO:0003709) |
| 0.0 | 4.7 | GO:0003714 | transcription corepressor activity(GO:0003714) |
| 0.0 | 0.4 | GO:0051183 | vitamin transporter activity(GO:0051183) |
| 0.0 | 0.3 | GO:0005521 | lamin binding(GO:0005521) |
| 0.0 | 0.5 | GO:0004708 | MAP kinase kinase activity(GO:0004708) |
| 0.0 | 0.1 | GO:0043891 | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891) |
| 0.0 | 0.1 | GO:0003886 | DNA (cytosine-5-)-methyltransferase activity(GO:0003886) |
| 0.0 | 0.2 | GO:0015280 | ligand-gated sodium channel activity(GO:0015280) |
| 0.0 | 0.3 | GO:0048306 | calcium-dependent protein binding(GO:0048306) |
| 0.0 | 0.3 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.0 | 0.1 | GO:0051766 | inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766) |
| 0.0 | 0.1 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.0 | 1.7 | GO:0031625 | ubiquitin protein ligase binding(GO:0031625) ubiquitin-like protein ligase binding(GO:0044389) |
| 0.0 | 0.9 | GO:0017048 | Rho GTPase binding(GO:0017048) |
| 0.0 | 0.1 | GO:0001848 | complement binding(GO:0001848) |
| 0.0 | 0.1 | GO:0045295 | gamma-catenin binding(GO:0045295) |
| 0.0 | 0.3 | GO:0004383 | guanylate cyclase activity(GO:0004383) |
| 0.0 | 0.2 | GO:0005537 | mannose binding(GO:0005537) |
| 0.0 | 0.1 | GO:0016714 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714) |
| 0.0 | 0.2 | GO:0004622 | lysophospholipase activity(GO:0004622) |
| 0.0 | 0.1 | GO:0004300 | enoyl-CoA hydratase activity(GO:0004300) |
| 0.0 | 8.1 | GO:0005509 | calcium ion binding(GO:0005509) |
| 0.0 | 0.1 | GO:0005243 | gap junction channel activity(GO:0005243) |
| 0.0 | 0.3 | GO:0042169 | SH2 domain binding(GO:0042169) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.4 | ST_ADRENERGIC | Adrenergic Pathway |
| 0.1 | 4.6 | SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES | Genes related to the insulin receptor pathway |
| 0.0 | 2.4 | SIG_CHEMOTAXIS | Genes related to chemotaxis |
| 0.0 | 0.6 | ST_STAT3_PATHWAY | STAT3 Pathway |
| 0.0 | 0.2 | ST_IL_13_PATHWAY | Interleukin 13 (IL-13) Pathway |
| 0.0 | 0.8 | SIG_CD40PATHWAYMAP | Genes related to CD40 signaling |
| 0.0 | 0.1 | SIG_IL4RECEPTOR_IN_B_LYPHOCYTES | Genes related to IL4 rceptor signaling in B lymphocytes |
| 0.0 | 1.3 | ST_FAS_SIGNALING_PATHWAY | Fas Signaling Pathway |
| 0.0 | 0.9 | ST_INTEGRIN_SIGNALING_PATHWAY | Integrin Signaling Pathway |
|
|
|