Motif ID: NHLH1

Z-value: 0.755


Transcription factors associated with NHLH1:

Gene SymbolEntrez IDGene Name
NHLH1 ENSG00000171786.5 NHLH1



Activity profile for motif NHLH1.

activity profile for motif NHLH1


Sorted Z-values histogram for motif NHLH1

Sorted Z-values for motif NHLH1



Network of associatons between targets according to the STRING database.



First level regulatory network of NHLH1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_32022733 1.593 ENST00000438237.2
ENST00000396556.2
OSBPL10

oxysterol binding protein-like 10

chr12_-_52887034 1.380 ENST00000330722.6
KRT6A
keratin 6A
chr1_+_20915409 0.987 ENST00000375071.3
CDA
cytidine deaminase
chr12_-_52867569 0.921 ENST00000252250.6
KRT6C
keratin 6C
chr5_+_52776228 0.911 ENST00000256759.3
FST
follistatin
chr20_-_14318248 0.869 ENST00000378053.3
ENST00000341420.4
FLRT3

fibronectin leucine rich transmembrane protein 3

chr6_+_30848557 0.865 ENST00000460944.2
ENST00000324771.8
DDR1

discoidin domain receptor tyrosine kinase 1

chr5_+_52776449 0.834 ENST00000396947.3
FST
follistatin
chr16_+_22825475 0.801 ENST00000261374.3
HS3ST2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr4_+_75311019 0.762 ENST00000502307.1
AREG
amphiregulin
chr4_+_75310851 0.724 ENST00000395748.3
ENST00000264487.2
AREG

amphiregulin

chr5_-_16936340 0.626 ENST00000507288.1
ENST00000513610.1
MYO10

myosin X

chr19_+_38755203 0.619 ENST00000587090.1
ENST00000454580.3
SPINT2

serine peptidase inhibitor, Kunitz type, 2

chr5_-_1882858 0.617 ENST00000511126.1
ENST00000231357.2
IRX4

iroquois homeobox 4

chr19_+_38755042 0.584 ENST00000301244.7
SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr1_-_237167718 0.560 ENST00000464121.2
MT1HL1
metallothionein 1H-like 1
chr5_+_76114758 0.523 ENST00000514165.1
ENST00000296677.4
F2RL1

coagulation factor II (thrombin) receptor-like 1

chr20_+_30193083 0.518 ENST00000376112.3
ENST00000376105.3
ID1

inhibitor of DNA binding 1, dominant negative helix-loop-helix protein

chr1_-_53387386 0.507 ENST00000467988.1
ENST00000358358.5
ENST00000371522.4
ECHDC2


enoyl CoA hydratase domain containing 2


chr2_-_31360887 0.494 ENST00000420311.2
ENST00000356174.3
ENST00000324589.5
GALNT14


UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)


chr1_-_209979375 0.486 ENST00000367021.3
IRF6
interferon regulatory factor 6
chr11_-_6341844 0.482 ENST00000303927.3
PRKCDBP
protein kinase C, delta binding protein
chr8_-_125740514 0.478 ENST00000325064.5
ENST00000518547.1
MTSS1

metastasis suppressor 1

chr1_-_85930823 0.467 ENST00000284031.8
ENST00000539042.1
DDAH1

dimethylarginine dimethylaminohydrolase 1

chr8_+_104311059 0.452 ENST00000358755.4
ENST00000523739.1
ENST00000540287.1
FZD6


frizzled family receptor 6


chr6_-_30712313 0.448 ENST00000376377.2
ENST00000259874.5
IER3

immediate early response 3

chr8_+_86376081 0.446 ENST00000285379.5
CA2
carbonic anhydrase II
chr3_-_185542761 0.443 ENST00000457616.2
ENST00000346192.3
IGF2BP2

insulin-like growth factor 2 mRNA binding protein 2

chr11_-_27494309 0.428 ENST00000389858.4
LGR4
leucine-rich repeat containing G protein-coupled receptor 4
chr11_-_66725837 0.414 ENST00000393958.2
ENST00000393960.1
ENST00000524491.1
ENST00000355677.3
PC



pyruvate carboxylase



chr11_-_27494279 0.405 ENST00000379214.4
LGR4
leucine-rich repeat containing G protein-coupled receptor 4
chr13_-_45150392 0.392 ENST00000501704.2
TSC22D1
TSC22 domain family, member 1
chr14_-_61748550 0.392 ENST00000555868.1
TMEM30B
transmembrane protein 30B
chr4_-_102268484 0.392 ENST00000394853.4
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr20_+_44036900 0.389 ENST00000443296.1
DBNDD2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr19_-_19051103 0.388 ENST00000542541.2
ENST00000433218.2
HOMER3

homer homolog 3 (Drosophila)

chr2_+_69001913 0.376 ENST00000409030.3
ENST00000409220.1
ARHGAP25

Rho GTPase activating protein 25

chr11_-_6341724 0.372 ENST00000530979.1
PRKCDBP
protein kinase C, delta binding protein
chr18_+_3449695 0.367 ENST00000343820.5
TGIF1
TGFB-induced factor homeobox 1
chr10_+_123923105 0.365 ENST00000368999.1
TACC2
transforming, acidic coiled-coil containing protein 2
chr20_+_44036620 0.359 ENST00000372710.3
DBNDD2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr11_-_65374430 0.346 ENST00000532507.1
MAP3K11
mitogen-activated protein kinase kinase kinase 11
chr5_+_102201722 0.344 ENST00000274392.9
ENST00000455264.2
PAM

peptidylglycine alpha-amidating monooxygenase

chr12_+_53491220 0.337 ENST00000548547.1
ENST00000301464.3
IGFBP6

insulin-like growth factor binding protein 6

chr4_-_102268628 0.334 ENST00000323055.6
ENST00000512215.1
ENST00000394854.3
PPP3CA


protein phosphatase 3, catalytic subunit, alpha isozyme


chr3_-_45187843 0.333 ENST00000296129.1
ENST00000425231.2
CDCP1

CUB domain containing protein 1

chr10_+_123922941 0.332 ENST00000360561.3
TACC2
transforming, acidic coiled-coil containing protein 2
chr18_+_3449821 0.332 ENST00000407501.2
ENST00000405385.3
ENST00000546979.1
TGIF1


TGFB-induced factor homeobox 1


chr14_-_54423529 0.324 ENST00000245451.4
ENST00000559087.1
BMP4

bone morphogenetic protein 4

chr6_+_30851840 0.321 ENST00000511510.1
ENST00000376569.3
ENST00000376575.3
ENST00000376570.4
ENST00000446312.1
ENST00000504927.1
DDR1





discoidin domain receptor tyrosine kinase 1





chr17_-_27278304 0.316 ENST00000577226.1
PHF12
PHD finger protein 12
chr10_+_123923205 0.316 ENST00000369004.3
ENST00000260733.3
TACC2

transforming, acidic coiled-coil containing protein 2

chr16_+_68771128 0.312 ENST00000261769.5
ENST00000422392.2
CDH1

cadherin 1, type 1, E-cadherin (epithelial)

chr17_+_39411636 0.310 ENST00000394008.1
KRTAP9-9
keratin associated protein 9-9
chrX_+_9754461 0.309 ENST00000380913.3
SHROOM2
shroom family member 2
chr11_+_394196 0.308 ENST00000331563.2
ENST00000531857.1
PKP3

plakophilin 3

chr5_+_102201687 0.300 ENST00000304400.7
PAM
peptidylglycine alpha-amidating monooxygenase
chr10_-_103347883 0.300 ENST00000339310.3
ENST00000370158.3
ENST00000299206.4
ENST00000456836.2
ENST00000413344.1
ENST00000429502.1
ENST00000430045.1
ENST00000370172.1
ENST00000436284.2
ENST00000370162.3
POLL









polymerase (DNA directed), lambda









chr5_+_102201509 0.297 ENST00000348126.2
ENST00000379787.4
PAM

peptidylglycine alpha-amidating monooxygenase

chr4_-_41216492 0.287 ENST00000503503.1
ENST00000509446.1
ENST00000503264.1
ENST00000508707.1
ENST00000508593.1
APBB2




amyloid beta (A4) precursor protein-binding, family B, member 2




chrX_+_150151752 0.279 ENST00000325307.7
HMGB3
high mobility group box 3
chr4_-_41216473 0.275 ENST00000513140.1
APBB2
amyloid beta (A4) precursor protein-binding, family B, member 2
chr1_-_6662919 0.270 ENST00000377658.4
ENST00000377663.3
KLHL21

kelch-like family member 21

chrX_+_110187513 0.269 ENST00000446737.1
ENST00000425146.1
PAK3

p21 protein (Cdc42/Rac)-activated kinase 3

chrX_+_107069063 0.258 ENST00000262843.6
MID2
midline 2
chr2_-_235405168 0.256 ENST00000339728.3
ARL4C
ADP-ribosylation factor-like 4C
chr1_-_225840747 0.252 ENST00000366843.2
ENST00000366844.3
ENAH

enabled homolog (Drosophila)

chr11_-_35441524 0.249 ENST00000395750.1
ENST00000449068.1
SLC1A2

solute carrier family 1 (glial high affinity glutamate transporter), member 2

chr7_-_27170352 0.246 ENST00000428284.2
ENST00000360046.5
HOXA4

homeobox A4

chr1_+_13910479 0.242 ENST00000509009.1
PDPN
podoplanin
chr12_+_57984965 0.226 ENST00000540759.2
ENST00000551772.1
ENST00000550465.1
ENST00000354947.5
PIP4K2C



phosphatidylinositol-5-phosphate 4-kinase, type II, gamma



chr5_-_95297534 0.220 ENST00000513343.1
ENST00000431061.2
ELL2

elongation factor, RNA polymerase II, 2

chr11_+_67070919 0.220 ENST00000308127.4
ENST00000308298.7
SSH3

slingshot protein phosphatase 3

chr3_-_99833333 0.220 ENST00000354552.3
ENST00000331335.5
ENST00000398326.2
FILIP1L


filamin A interacting protein 1-like


chr16_-_29910365 0.219 ENST00000346932.5
ENST00000350527.3
ENST00000537485.1
ENST00000568380.1
SEZ6L2



seizure related 6 homolog (mouse)-like 2



chr18_+_3448455 0.213 ENST00000549780.1
TGIF1
TGFB-induced factor homeobox 1
chr11_-_35441597 0.212 ENST00000395753.1
SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr12_-_118541743 0.210 ENST00000359236.5
VSIG10
V-set and immunoglobulin domain containing 10
chr21_-_46293644 0.205 ENST00000330938.3
PTTG1IP
pituitary tumor-transforming 1 interacting protein
chr3_-_119813264 0.202 ENST00000264235.8
GSK3B
glycogen synthase kinase 3 beta
chr6_+_31895254 0.200 ENST00000299367.5
ENST00000442278.2
C2

complement component 2

chr1_-_182360918 0.200 ENST00000339526.4
GLUL
glutamate-ammonia ligase
chr4_-_139163491 0.198 ENST00000280612.5
SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr1_+_13910194 0.195 ENST00000376057.4
ENST00000510906.1
PDPN

podoplanin

chr1_+_60280458 0.195 ENST00000455990.1
ENST00000371208.3
HOOK1

hook microtubule-tethering protein 1

chr2_-_178483694 0.195 ENST00000355689.5
TTC30A
tetratricopeptide repeat domain 30A
chr4_-_41216619 0.195 ENST00000508676.1
ENST00000506352.1
ENST00000295974.8
APBB2


amyloid beta (A4) precursor protein-binding, family B, member 2


chr11_+_71249071 0.195 ENST00000398534.3
KRTAP5-8
keratin associated protein 5-8
chr7_-_27169801 0.194 ENST00000511914.1
HOXA4
homeobox A4
chr21_-_46293586 0.193 ENST00000445724.2
ENST00000397887.3
PTTG1IP

pituitary tumor-transforming 1 interacting protein

chr10_-_35104185 0.190 ENST00000374789.3
ENST00000374788.3
ENST00000346874.4
ENST00000374794.3
ENST00000350537.4
ENST00000374790.3
ENST00000374776.1
ENST00000374773.1
ENST00000545693.1
ENST00000545260.1
ENST00000340077.5
PARD3










par-3 family cell polarity regulator










chr1_-_19536744 0.189 ENST00000375267.2
ENST00000375217.2
ENST00000375226.2
ENST00000375254.3
UBR4



ubiquitin protein ligase E3 component n-recognin 4



chr1_+_90287480 0.187 ENST00000394593.3
LRRC8D
leucine rich repeat containing 8 family, member D
chr19_+_45281118 0.186 ENST00000270279.3
ENST00000341505.4
CBLC

Cbl proto-oncogene C, E3 ubiquitin protein ligase

chr11_+_64948665 0.185 ENST00000533820.1
CAPN1
calpain 1, (mu/I) large subunit
chr6_+_31895467 0.183 ENST00000556679.1
ENST00000456570.1
CFB
CFB
complement factor B
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr14_-_104313824 0.181 ENST00000553739.1
ENST00000202556.9
PPP1R13B

protein phosphatase 1, regulatory subunit 13B

chr4_+_154074217 0.178 ENST00000437508.2
TRIM2
tripartite motif containing 2
chr2_+_236578248 0.178 ENST00000409538.1
AGAP1
ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr2_+_70485220 0.177 ENST00000433351.2
ENST00000264441.5
PCYOX1

prenylcysteine oxidase 1

chr6_+_31895480 0.177 ENST00000418949.2
ENST00000383177.3
ENST00000477310.1
C2

CFB
complement component 2

Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr1_-_182360498 0.177 ENST00000417584.2
GLUL
glutamate-ammonia ligase
chrX_-_84634737 0.176 ENST00000262753.4
POF1B
premature ovarian failure, 1B
chr19_-_47164386 0.174 ENST00000391916.2
ENST00000410105.2
DACT3

dishevelled-binding antagonist of beta-catenin 3

chr6_-_80657292 0.171 ENST00000369816.4
ELOVL4
ELOVL fatty acid elongase 4
chr2_-_73340146 0.171 ENST00000258098.6
RAB11FIP5
RAB11 family interacting protein 5 (class I)
chr15_+_25200074 0.171 ENST00000390687.4
ENST00000584968.1
ENST00000346403.6
ENST00000554227.2
SNRPN



small nuclear ribonucleoprotein polypeptide N



chr1_+_955448 0.170 ENST00000379370.2
AGRN
agrin
chr14_+_62162258 0.164 ENST00000337138.4
ENST00000394997.1
HIF1A

hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)

chr1_-_182361327 0.163 ENST00000331872.6
ENST00000311223.5
GLUL

glutamate-ammonia ligase

chr14_-_24551195 0.162 ENST00000560550.1
NRL
neural retina leucine zipper
chr5_-_95297678 0.161 ENST00000237853.4
ELL2
elongation factor, RNA polymerase II, 2
chr20_+_34043085 0.160 ENST00000397527.1
ENST00000342580.4
CEP250

centrosomal protein 250kDa

chr7_-_11871815 0.156 ENST00000423059.4
THSD7A
thrombospondin, type I, domain containing 7A
chr4_-_54930790 0.156 ENST00000263921.3
CHIC2
cysteine-rich hydrophobic domain 2
chr17_-_39191107 0.153 ENST00000344363.5
KRTAP1-3
keratin associated protein 1-3
chr18_-_30050395 0.153 ENST00000269209.6
ENST00000399218.4
GAREM

GRB2 associated, regulator of MAPK1

chr8_-_144897549 0.152 ENST00000356994.2
ENST00000320476.3
SCRIB

scribbled planar cell polarity protein

chr8_-_144897138 0.151 ENST00000377533.3
SCRIB
scribbled planar cell polarity protein
chr16_-_90085824 0.150 ENST00000002501.6
DBNDD1
dysbindin (dystrobrevin binding protein 1) domain containing 1
chr16_+_1756162 0.148 ENST00000250894.4
ENST00000356010.5
MAPK8IP3

mitogen-activated protein kinase 8 interacting protein 3

chr13_-_96296944 0.148 ENST00000361396.2
ENST00000376829.2
DZIP1

DAZ interacting zinc finger protein 1

chr7_-_148725733 0.147 ENST00000286091.4
PDIA4
protein disulfide isomerase family A, member 4
chr7_+_766320 0.147 ENST00000297440.6
ENST00000313147.5
HEATR2

HEAT repeat containing 2

chr9_+_114393634 0.147 ENST00000556107.1
ENST00000374294.3
DNAJC25
DNAJC25-GNG10
DnaJ (Hsp40) homolog, subfamily C , member 25
DNAJC25-GNG10 readthrough
chr19_+_35521572 0.147 ENST00000262631.5
SCN1B
sodium channel, voltage-gated, type I, beta subunit
chrX_+_150151824 0.146 ENST00000455596.1
ENST00000448905.2
HMGB3

high mobility group box 3

chr12_-_123752624 0.143 ENST00000542174.1
ENST00000535796.1
CDK2AP1

cyclin-dependent kinase 2 associated protein 1

chr14_-_24551137 0.141 ENST00000396995.1
NRL
neural retina leucine zipper
chr19_+_17666403 0.141 ENST00000252599.4
COLGALT1
collagen beta(1-O)galactosyltransferase 1
chr1_-_38273840 0.140 ENST00000373044.2
YRDC
yrdC N(6)-threonylcarbamoyltransferase domain containing
chr1_+_15272271 0.140 ENST00000400797.3
KAZN
kazrin, periplakin interacting protein
chr1_+_90286562 0.139 ENST00000525774.1
ENST00000337338.5
LRRC8D

leucine rich repeat containing 8 family, member D

chr7_-_123389104 0.138 ENST00000223023.4
WASL
Wiskott-Aldrich syndrome-like
chr16_-_67694129 0.136 ENST00000602320.1
ACD
adrenocortical dysplasia homolog (mouse)
chr20_-_33680635 0.136 ENST00000252015.2
TRPC4AP
transient receptor potential cation channel, subfamily C, member 4 associated protein
chr20_-_33680588 0.135 ENST00000451813.2
ENST00000432634.2
TRPC4AP

transient receptor potential cation channel, subfamily C, member 4 associated protein

chr3_+_142442841 0.135 ENST00000476941.1
ENST00000273482.6
TRPC1

transient receptor potential cation channel, subfamily C, member 1

chr4_+_30723003 0.134 ENST00000543491.1
PCDH7
protocadherin 7
chr6_+_43395272 0.134 ENST00000372530.4
ABCC10
ATP-binding cassette, sub-family C (CFTR/MRP), member 10
chr20_+_47538357 0.134 ENST00000371917.4
ARFGEF2
ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
chr15_-_52472078 0.133 ENST00000396335.4
ENST00000560116.1
ENST00000358784.7
GNB5


guanine nucleotide binding protein (G protein), beta 5


chr8_+_24772455 0.132 ENST00000433454.2
NEFM
neurofilament, medium polypeptide
chr17_+_28705921 0.130 ENST00000225719.4
CPD
carboxypeptidase D
chr14_-_107211459 0.129 ENST00000390636.2
IGHV3-73
immunoglobulin heavy variable 3-73
chr4_+_3768075 0.125 ENST00000509482.1
ENST00000330055.5
ADRA2C

adrenoceptor alpha 2C

chr6_+_43543864 0.124 ENST00000372236.4
ENST00000535400.1
POLH

polymerase (DNA directed), eta

chr13_+_28194873 0.123 ENST00000302979.3
POLR1D
polymerase (RNA) I polypeptide D, 16kDa
chr7_+_99613212 0.122 ENST00000426572.1
ENST00000535170.1
ZKSCAN1

zinc finger with KRAB and SCAN domains 1

chr15_+_25200108 0.122 ENST00000579070.1
ENST00000577565.1
ENST00000577949.1
ENST00000338094.6
ENST00000338327.4
SNRPN

SNURF


small nuclear ribonucleoprotein polypeptide N

SNRPN upstream reading frame protein


chr19_+_16186903 0.122 ENST00000588507.1
TPM4
tropomyosin 4
chr16_+_67465016 0.121 ENST00000326152.5
HSD11B2
hydroxysteroid (11-beta) dehydrogenase 2
chr7_-_44924939 0.121 ENST00000395699.2
PURB
purine-rich element binding protein B
chr2_+_27274506 0.120 ENST00000451003.1
ENST00000323064.8
ENST00000360131.4
AGBL5


ATP/GTP binding protein-like 5


chr11_-_34379546 0.119 ENST00000435224.2
ABTB2
ankyrin repeat and BTB (POZ) domain containing 2
chr17_+_55162453 0.118 ENST00000575322.1
ENST00000337714.3
ENST00000314126.3
AKAP1


A kinase (PRKA) anchor protein 1


chr7_+_130131907 0.117 ENST00000223215.4
ENST00000437945.1
MEST

mesoderm specific transcript

chr17_-_66453562 0.115 ENST00000262139.5
ENST00000546360.1
WIPI1

WD repeat domain, phosphoinositide interacting 1

chr14_+_24583836 0.113 ENST00000559115.1
ENST00000558215.1
ENST00000557810.1
ENST00000561375.1
ENST00000446197.3
ENST00000559796.1
ENST00000560713.1
ENST00000560901.1
ENST00000559382.1
DCAF11








DDB1 and CUL4 associated factor 11








chr1_-_21671968 0.112 ENST00000415912.2
ECE1
endothelin converting enzyme 1
chr4_-_89744365 0.111 ENST00000513837.1
ENST00000503556.1
FAM13A

family with sequence similarity 13, member A

chr22_+_32340481 0.110 ENST00000397492.1
YWHAH
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
chr19_+_48876300 0.110 ENST00000600863.1
ENST00000601610.1
ENST00000595322.1
SYNGR4


synaptogyrin 4


chr20_+_34042962 0.110 ENST00000446710.1
ENST00000420564.1
CEP250

centrosomal protein 250kDa

chr1_+_202317815 0.109 ENST00000608999.1
ENST00000336894.4
ENST00000480184.1
PPP1R12B


protein phosphatase 1, regulatory subunit 12B


chr9_+_125703282 0.108 ENST00000373647.4
ENST00000402311.1
RABGAP1

RAB GTPase activating protein 1

chr14_-_24911868 0.107 ENST00000554698.1
SDR39U1
short chain dehydrogenase/reductase family 39U, member 1
chr8_+_42995548 0.107 ENST00000458501.2
ENST00000379644.4
HGSNAT

heparan-alpha-glucosaminide N-acetyltransferase

chr6_+_43543942 0.106 ENST00000372226.1
ENST00000443535.1
POLH

polymerase (DNA directed), eta

chr6_-_31681839 0.106 ENST00000461287.1
ENST00000409239.1
XXbac-BPG32J3.20
LY6G6E
Uncharacterized protein
lymphocyte antigen 6 complex, locus G6E (pseudogene)
chr22_+_32340447 0.105 ENST00000248975.5
YWHAH
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
chr12_+_122064398 0.105 ENST00000330079.7
ORAI1
ORAI calcium release-activated calcium modulator 1
chr13_-_72440901 0.105 ENST00000359684.2
DACH1
dachshund homolog 1 (Drosophila)
chr4_-_122854193 0.105 ENST00000513531.1
TRPC3
transient receptor potential cation channel, subfamily C, member 3
chr2_+_233562015 0.105 ENST00000427233.1
ENST00000373566.3
ENST00000373563.4
ENST00000428883.1
ENST00000456491.1
ENST00000409480.1
ENST00000421433.1
ENST00000425040.1
ENST00000430720.1
ENST00000409547.1
ENST00000423659.1
ENST00000409196.3
ENST00000409451.3
ENST00000429187.1
ENST00000440945.1
GIGYF2














GRB10 interacting GYF protein 2














chr3_+_5020801 0.104 ENST00000256495.3
BHLHE40
basic helix-loop-helix family, member e40
chr16_-_82203780 0.103 ENST00000563504.1
ENST00000569021.1
ENST00000258169.4
MPHOSPH6


M-phase phosphoprotein 6


chr12_-_110318226 0.103 ENST00000544393.1
GLTP
glycolipid transfer protein
chr8_-_67579418 0.103 ENST00000310421.4
VCPIP1
valosin containing protein (p97)/p47 complex interacting protein 1
chr1_-_27693349 0.101 ENST00000374040.3
ENST00000357582.2
ENST00000493901.1
MAP3K6


mitogen-activated protein kinase kinase kinase 6


chr14_-_24584138 0.101 ENST00000558280.1
ENST00000561028.1
NRL

neural retina leucine zipper

chr3_+_124303539 0.101 ENST00000428018.2
KALRN
kalirin, RhoGEF kinase
chr1_+_24969755 0.100 ENST00000447431.2
ENST00000374389.4
SRRM1

serine/arginine repetitive matrix 1

chr4_-_89744314 0.098 ENST00000508369.1
FAM13A
family with sequence similarity 13, member A
chr7_-_128045984 0.098 ENST00000470772.1
ENST00000480861.1
ENST00000496200.1
IMPDH1


IMP (inosine 5'-monophosphate) dehydrogenase 1


chrX_+_47004599 0.098 ENST00000329236.7
RBM10
RNA binding motif protein 10
chr1_-_3713042 0.098 ENST00000378251.1
LRRC47
leucine rich repeat containing 47
chr2_+_231902193 0.096 ENST00000373640.4
C2orf72
chromosome 2 open reading frame 72
chr5_-_94620239 0.096 ENST00000515393.1
MCTP1
multiple C2 domains, transmembrane 1
chr6_-_82462425 0.095 ENST00000369754.3
ENST00000320172.6
ENST00000369756.3
FAM46A


family with sequence similarity 46, member A


chr1_+_156105878 0.095 ENST00000508500.1
LMNA
lamin A/C
chr14_-_24911971 0.095 ENST00000555365.1
ENST00000399395.3
SDR39U1

short chain dehydrogenase/reductase family 39U, member 1

chr17_-_79139817 0.095 ENST00000326724.4
AATK
apoptosis-associated tyrosine kinase
chr16_+_67562702 0.094 ENST00000379312.3
ENST00000042381.4
ENST00000540839.3
FAM65A


family with sequence similarity 65, member A


chr1_+_78511586 0.093 ENST00000370759.3
GIPC2
GIPC PDZ domain containing family, member 2
chr1_+_3388181 0.093 ENST00000418137.1
ENST00000413250.2
ARHGEF16

Rho guanine nucleotide exchange factor (GEF) 16

chr19_+_39989535 0.092 ENST00000356433.5
DLL3
delta-like 3 (Drosophila)
chr20_+_8112824 0.092 ENST00000378641.3
PLCB1
phospholipase C, beta 1 (phosphoinositide-specific)
chr21_+_34697258 0.092 ENST00000442071.1
ENST00000442357.2
IFNAR1

interferon (alpha, beta and omega) receptor 1

chr7_-_32110451 0.089 ENST00000396191.1
ENST00000396182.2
PDE1C

phosphodiesterase 1C, calmodulin-dependent 70kDa


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0019858 cytosine metabolic process(GO:0019858)
0.3 1.7 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.2 0.5 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.1 0.5 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 0.5 GO:0030035 microspike assembly(GO:0030035)
0.1 0.4 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
0.1 0.3 GO:0048389 intermediate mesoderm development(GO:0048389) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) bud dilation involved in lung branching(GO:0060503) branch elongation involved in ureteric bud branching(GO:0060681) regulation of transcription from RNA polymerase II promoter involved in kidney development(GO:0060994) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) pulmonary artery morphogenesis(GO:0061156) cell proliferation involved in mesonephros development(GO:0061209) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) negative regulation of mesonephros development(GO:0061218) pattern specification involved in mesonephros development(GO:0061227) renal system vasculature morphogenesis(GO:0061438) kidney vasculature morphogenesis(GO:0061439) BMP signaling pathway involved in nephric duct formation(GO:0071893) glomerular visceral epithelial cell development(GO:0072015) comma-shaped body morphogenesis(GO:0072049) regulation of branch elongation involved in ureteric bud branching(GO:0072095) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in kidney development(GO:0072098) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) glomerulus morphogenesis(GO:0072102) glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104) mesenchymal cell proliferation involved in ureteric bud development(GO:0072138) nephric duct formation(GO:0072179) ureter urothelium development(GO:0072190) ureter epithelial cell differentiation(GO:0072192) ureter morphogenesis(GO:0072197) metanephric comma-shaped body morphogenesis(GO:0072278) glomerular epithelial cell development(GO:0072310) negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.1 0.4 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.1 0.3 GO:1902414 protein localization to adherens junction(GO:0071896) protein localization to cell junction(GO:1902414)
0.1 0.2 GO:0031133 regulation of axon diameter(GO:0031133) regulation of cell projection size(GO:0032536)
0.1 0.2 GO:0071109 superior temporal gyrus development(GO:0071109)
0.1 0.3 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.1 0.5 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1 0.3 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.1 0.2 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 0.5 GO:0060644 mammary gland epithelial cell differentiation(GO:0060644)
0.1 0.2 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367)
0.1 0.2 GO:1904396 regulation of synaptic growth at neuromuscular junction(GO:0008582) regulation of neuromuscular junction development(GO:1904396)
0.1 0.2 GO:0097709 connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
0.1 0.2 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.1 1.4 GO:0007398 ectoderm development(GO:0007398)
0.0 0.3 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.2 GO:0008356 asymmetric cell division(GO:0008356)
0.0 0.2 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.0 0.1 GO:0070672 response to interleukin-15(GO:0070672)
0.0 0.4 GO:0001946 lymphangiogenesis(GO:0001946) lymph vessel morphogenesis(GO:0036303)
0.0 0.3 GO:0045176 apical protein localization(GO:0045176)
0.0 1.0 GO:0060749 mammary gland alveolus development(GO:0060749) mammary gland lobule development(GO:0061377)
0.0 0.8 GO:0045749 obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749)
0.0 0.1 GO:0071883 adrenergic receptor signaling pathway(GO:0071875) activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0 0.1 GO:0035608 protein deglutamylation(GO:0035608)
0.0 0.1 GO:1904742 regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381) regulation of telomeric DNA binding(GO:1904742) positive regulation of telomeric DNA binding(GO:1904744)
0.0 0.4 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.5 GO:0000052 citrulline metabolic process(GO:0000052) arginine catabolic process(GO:0006527)
0.0 0.2 GO:0046836 glycolipid transport(GO:0046836)
0.0 0.1 GO:0070669 response to interleukin-2(GO:0070669)
0.0 0.2 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.0 0.4 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 0.1 GO:0034126 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124) positive regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034126)
0.0 0.1 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0 0.2 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.0 1.2 GO:0045740 positive regulation of DNA replication(GO:0045740)
0.0 0.1 GO:0060454 positive regulation of gastric acid secretion(GO:0060454) regulation of establishment of blood-brain barrier(GO:0090210) negative regulation of establishment of blood-brain barrier(GO:0090212)
0.0 0.3 GO:0002566 somatic diversification of immune receptors via somatic mutation(GO:0002566) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.5 GO:0050927 positive regulation of positive chemotaxis(GO:0050927)
0.0 0.1 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.1 GO:0046541 saliva secretion(GO:0046541)
0.0 0.1 GO:0001977 renal system process involved in regulation of blood volume(GO:0001977)
0.0 0.1 GO:0006896 Golgi to endosome transport(GO:0006895) Golgi to vacuole transport(GO:0006896)
0.0 0.1 GO:0043163 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.0 0.1 GO:0090343 positive regulation of cell aging(GO:0090343)
0.0 0.2 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.0 0.3 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.5 GO:0072359 cardiovascular system development(GO:0072358) circulatory system development(GO:0072359)
0.0 0.1 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.2 GO:0098927 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0 0.1 GO:0009649 entrainment of circadian clock(GO:0009649)
0.0 0.3 GO:0051322 anaphase(GO:0051322)
0.0 0.4 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.0 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.0 0.3 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.0 GO:0070244 negative regulation of thymocyte apoptotic process(GO:0070244)
0.0 0.1 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.0 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.0 GO:1901724 positive regulation of cell proliferation involved in kidney development(GO:1901724)
0.0 0.5 GO:0043534 blood vessel endothelial cell migration(GO:0043534)
0.0 0.1 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.0 0.8 GO:0007623 circadian rhythm(GO:0007623)
0.0 0.1 GO:0035313 wound healing, spreading of epidermal cells(GO:0035313) wound healing, spreading of cells(GO:0044319) epiboly(GO:0090504) epiboly involved in wound healing(GO:0090505)
0.0 0.0 GO:0051547 regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0005955 calcineurin complex(GO:0005955)
0.1 3.0 GO:0045095 keratin filament(GO:0045095)
0.1 0.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.3 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 0.3 GO:0016342 catenin complex(GO:0016342)
0.0 0.5 GO:0030673 axolemma(GO:0030673)
0.0 0.5 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.3 GO:0005827 polar microtubule(GO:0005827)
0.0 0.1 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032) PAS complex(GO:0070772)
0.0 0.3 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.3 GO:0005883 neurofilament(GO:0005883)
0.0 0.2 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.2 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.3 GO:0031941 filamentous actin(GO:0031941)
0.0 0.4 GO:0030057 desmosome(GO:0030057)
0.0 0.1 GO:0014704 intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.0 0.3 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.1 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.4 GO:0005902 microvillus(GO:0005902)
0.0 0.1 GO:0005638 lamin filament(GO:0005638)
0.0 0.2 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.0 GO:0036452 ESCRT III complex(GO:0000815) ESCRT complex(GO:0036452)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.2 1.0 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 0.5 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 1.6 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 0.5 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 0.5 GO:0015057 thrombin receptor activity(GO:0015057)
0.1 0.5 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.2 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.2 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.1 0.3 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.4 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 0.3 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 0.8 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.1 0.3 GO:0033989 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989)
0.0 0.3 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.0 0.4 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.8 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.1 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.0 0.4 GO:0009374 biotin binding(GO:0009374)
0.0 0.3 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.1 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0 0.1 GO:0032422 translation repressor activity, nucleic acid binding(GO:0000900) purine-rich negative regulatory element binding(GO:0032422)
0.0 0.2 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.4 GO:0001848 complement binding(GO:0001848)
0.0 0.3 GO:0042153 obsolete RPTP-like protein binding(GO:0042153)
0.0 0.3 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.3 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.2 GO:0017089 glycolipid transporter activity(GO:0017089)
0.0 0.1 GO:0004104 cholinesterase activity(GO:0004104)
0.0 0.2 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.1 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.3 GO:0016944 obsolete RNA polymerase II transcription elongation factor activity(GO:0016944)
0.0 0.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.7 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.2 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.1 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.2 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 1.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0008148 obsolete negative transcription elongation factor activity(GO:0008148)
0.0 0.0 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.0 0.3 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.1 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.2 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.0 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 1.2 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.1 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.0 1.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.1 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.7 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 ST_GA12_PATHWAY G alpha 12 Pathway