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Motif ID: NKX1-1

Z-value: 0.449

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr2_+_8822113	1.224	ENST00000396290.1 ENST00000331129.3	ID2	inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
chr1_-_221915418	0.559	ENST00000323825.3 ENST00000366899.3	DUSP10	dual specificity phosphatase 10
chr7_-_86849883	0.529	ENST00000433078.1	TMEM243	transmembrane protein 243, mitochondrial
chr7_+_26331541	0.523	ENST00000416246.1 ENST00000338523.4 ENST00000412416.1	SNX10	sorting nexin 10
chr3_-_105588231	0.425	ENST00000545639.1 ENST00000394027.3 ENST00000438603.1 ENST00000447441.1 ENST00000443752.1	CBLB	Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr4_+_128554081	0.392	ENST00000335251.6 ENST00000296461.5	INTU	inturned planar cell polarity protein
chr8_+_26371763	0.316	ENST00000521913.1	DPYSL2	dihydropyrimidinase-like 2
chr1_+_174843548	0.247	ENST00000478442.1 ENST00000465412.1	RABGAP1L	RAB GTPase activating protein 1-like
chr2_-_239197238	0.220	ENST00000254657.3	PER2	period circadian clock 2
chr18_-_33709268	0.201	ENST00000269187.5 ENST00000590986.1 ENST00000440549.2	SLC39A6	solute carrier family 39 (zinc transporter), member 6
chr3_+_57261743	0.196	ENST00000288266.3	APPL1	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
chr17_-_61777459	0.189	ENST00000578993.1 ENST00000583211.1 ENST00000259006.3	LIMD2	LIM domain containing 2
chr2_-_239197201	0.183	ENST00000254658.3	PER2	period circadian clock 2
chr14_-_24711865	0.173	ENST00000399423.4 ENST00000267415.7	TINF2	TERF1 (TRF1)-interacting nuclear factor 2
chr3_-_105587879	0.166	ENST00000264122.4 ENST00000403724.1 ENST00000405772.1	CBLB	Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr14_-_24711806	0.163	ENST00000540705.1 ENST00000538777.1 ENST00000558566.1 ENST00000559019.1	TINF2	TERF1 (TRF1)-interacting nuclear factor 2
chr17_-_8113886	0.161	ENST00000577833.1 ENST00000534871.1 ENST00000583915.1 ENST00000316199.6 ENST00000581511.1 ENST00000585124.1	AURKB	aurora kinase B
chr12_-_6961050	0.153	ENST00000538862.2	CDCA3	cell division cycle associated 3
chr12_+_7014126	0.149	ENST00000415834.1 ENST00000436789.1	LRRC23	leucine rich repeat containing 23
chr12_+_7014064	0.130	ENST00000443597.2	LRRC23	leucine rich repeat containing 23
chr17_-_45266542	0.127	ENST00000531206.1 ENST00000527547.1 ENST00000446365.2 ENST00000575483.1 ENST00000066544.3	CDC27	cell division cycle 27
chr8_+_98656693	0.126	ENST00000519934.1	MTDH	metadherin
chr7_+_50348268	0.126	ENST00000438033.1 ENST00000439701.1	IKZF1	IKAROS family zinc finger 1 (Ikaros)
chr12_+_7013897	0.116	ENST00000007969.8 ENST00000323702.5	LRRC23	leucine rich repeat containing 23
chr8_+_98656336	0.109	ENST00000336273.3	MTDH	metadherin
chr15_-_78526855	0.106	ENST00000541759.1 ENST00000558130.1	ACSBG1	acyl-CoA synthetase bubblegum family member 1
chr3_+_23851928	0.097	ENST00000467766.1 ENST00000424381.1	UBE2E1	ubiquitin-conjugating enzyme E2E 1
chr1_+_46972668	0.095	ENST00000371956.4 ENST00000360032.3	DMBX1	diencephalon/mesencephalon homeobox 1
chr17_-_44657017	0.085	ENST00000573185.1 ENST00000570550.1 ENST00000445552.2 ENST00000336125.5 ENST00000329240.4 ENST00000337845.7	ARL17A	ADP-ribosylation factor-like 17A
chr17_-_44439084	0.082	ENST00000575960.1 ENST00000575698.1 ENST00000571246.1 ENST00000434041.2 ENST00000570618.1 ENST00000450673.3	ARL17B	ADP-ribosylation factor-like 17B
chr14_-_24711470	0.081	ENST00000559969.1	TINF2	TERF1 (TRF1)-interacting nuclear factor 2
chr11_-_111741994	0.072	ENST00000398006.2	ALG9	ALG9, alpha-1,2-mannosyltransferase
chr11_-_71823715	0.069	ENST00000545944.1 ENST00000502597.2	ANAPC15	anaphase promoting complex subunit 15
chr11_-_62494821	0.069	ENST00000301785.5	HNRNPUL2	heterogeneous nuclear ribonucleoprotein U-like 2
chr11_-_71823796	0.066	ENST00000545680.1 ENST00000543587.1 ENST00000538393.1 ENST00000535234.1 ENST00000227618.4 ENST00000535503.1	ANAPC15	anaphase promoting complex subunit 15
chr1_-_51796226	0.064	ENST00000451380.1 ENST00000371747.3 ENST00000439482.1	TTC39A	tetratricopeptide repeat domain 39A
chr1_-_108507631	0.064	ENST00000527011.1 ENST00000370056.4	VAV3	vav 3 guanine nucleotide exchange factor
chr19_-_6424783	0.061	ENST00000398148.3	KHSRP	KH-type splicing regulatory protein
chr12_+_102513950	0.057	ENST00000378128.3 ENST00000327680.2 ENST00000541394.1 ENST00000543784.1	PARPBP	PARP1 binding protein
chr19_+_36249057	0.057	ENST00000301165.5 ENST00000536950.1 ENST00000537459.1 ENST00000421853.2	C19orf55	chromosome 19 open reading frame 55
chr4_-_103682145	0.055	ENST00000226578.4	MANBA	mannosidase, beta A, lysosomal
chr4_-_8873531	0.055	ENST00000400677.3	HMX1	H6 family homeobox 1
chr14_+_32798462	0.053	ENST00000280979.4	AKAP6	A kinase (PRKA) anchor protein 6
chr1_+_62439037	0.050	ENST00000545929.1	INADL	InaD-like (Drosophila)
chr9_+_139780942	0.049	ENST00000247668.2 ENST00000359662.3	TRAF2	TNF receptor-associated factor 2
chr19_+_45504688	0.047	ENST00000221452.8 ENST00000540120.1 ENST00000505236.1	RELB	v-rel avian reticuloendotheliosis viral oncogene homolog B
chr2_+_187371440	0.044	ENST00000445547.1	ZC3H15	zinc finger CCCH-type containing 15
chr17_-_8055747	0.043	ENST00000317276.4 ENST00000581703.1	PER1	period circadian clock 1
chr17_-_27418537	0.043	ENST00000408971.2	TIAF1	TGFB1-induced anti-apoptotic factor 1
chr1_-_51796987	0.043	ENST00000262676.5	TTC39A	tetratricopeptide repeat domain 39A
chr10_-_1095050	0.034	ENST00000381344.3	IDI1	isopentenyl-diphosphate delta isomerase 1
chr22_-_39151463	0.034	ENST00000405510.1 ENST00000433561.1	SUN2	Sad1 and UNC84 domain containing 2
chr12_-_23737534	0.033	ENST00000396007.2	SOX5	SRY (sex determining region Y)-box 5
chr12_+_2921788	0.029	ENST00000228799.2 ENST00000419778.2 ENST00000542548.1	ITFG2	integrin alpha FG-GAP repeat containing 2
chr6_-_82957433	0.028	ENST00000306270.7	IBTK	inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr10_+_120789223	0.028	ENST00000425699.1	NANOS1	nanos homolog 1 (Drosophila)
chr12_-_91451758	0.027	ENST00000266719.3	KERA	keratocan
chr15_+_64386261	0.025	ENST00000560829.1	SNX1	sorting nexin 1
chrX_-_47509887	0.024	ENST00000247161.3 ENST00000592066.1 ENST00000376983.3	ELK1	ELK1, member of ETS oncogene family
chr3_+_186560476	0.020	ENST00000320741.2 ENST00000444204.2	ADIPOQ	adiponectin, C1Q and collagen domain containing
chr3_+_186560462	0.020	ENST00000412955.2	ADIPOQ	adiponectin, C1Q and collagen domain containing
chr13_-_36050819	0.018	ENST00000379919.4	MAB21L1	mab-21-like 1 (C. elegans)
chr17_-_40337470	0.018	ENST00000293330.1	HCRT	hypocretin (orexin) neuropeptide precursor
chr4_-_66536196	0.015	ENST00000511294.1	EPHA5	EPH receptor A5
chr19_-_8070474	0.014	ENST00000407627.2 ENST00000593807.1	ELAVL1	ELAV like RNA binding protein 1
chr12_+_28410128	0.013	ENST00000381259.1 ENST00000381256.1	CCDC91	coiled-coil domain containing 91
chr7_+_144052381	0.011	ENST00000498580.1 ENST00000056217.5	ARHGEF5	Rho guanine nucleotide exchange factor (GEF) 5
chr20_-_50722183	0.010	ENST00000371523.4	ZFP64	ZFP64 zinc finger protein
chr4_-_66536057	0.009	ENST00000273854.3	EPHA5	EPH receptor A5
chrX_-_153363125	0.009	ENST00000407218.1 ENST00000453960.2	MECP2	methyl CpG binding protein 2 (Rett syndrome)
chrX_+_55026763	0.009	ENST00000374987.3	APEX2	APEX nuclease (apurinic/apyrimidinic endonuclease) 2
chr17_-_10372875	0.008	ENST00000255381.2	MYH4	myosin, heavy chain 4, skeletal muscle
chr11_+_72983246	0.007	ENST00000393590.2	P2RY6	pyrimidinergic receptor P2Y, G-protein coupled, 6
chr1_-_190446759	0.006	ENST00000367462.3	BRINP3	bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr15_-_78526942	0.003	ENST00000258873.4	ACSBG1	acyl-CoA synthetase bubblegum family member 1

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.2	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.1	0.4	GO:0010836	negative regulation of protein ADP-ribosylation(GO:0010836) negative regulation of protein glycosylation(GO:0060051)
0.1	0.6	GO:0046642	negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0	0.2	GO:0010508	positive regulation of autophagy(GO:0010508)
0.0	0.3	GO:0014049	positive regulation of glutamate secretion(GO:0014049)
0.0	0.1	GO:0001552	ovarian follicle atresia(GO:0001552)
0.0	0.6	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.0	0.2	GO:0034501	protein localization to kinetochore(GO:0034501)
0.0	0.5	GO:0007032	endosome organization(GO:0007032)
0.0	0.0	GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
0.0	0.1	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.1	GO:0008343	adult feeding behavior(GO:0008343)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0010370	perinucleolar chromocenter(GO:0010370)
0.1	0.5	GO:0000306	extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0	0.2	GO:0032133	chromosome passenger complex(GO:0032133)
0.0	0.2	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	0.2	GO:0031258	lamellipodium membrane(GO:0031258)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.6	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.1	GO:0042296	ISG15 transferase activity(GO:0042296)
0.0	0.3	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.0	0.2	GO:0043422	protein kinase B binding(GO:0043422)
0.0	0.1	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0	0.4	GO:0042162	telomeric DNA binding(GO:0042162)
0.0	0.5	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.0	0.0	GO:0005174	CD40 receptor binding(GO:0005174)

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