Motif ID: NKX2-2

Z-value: 0.583


Transcription factors associated with NKX2-2:

Gene SymbolEntrez IDGene Name
NKX2-2 ENSG00000125820.5 NKX2-2



Activity profile for motif NKX2-2.

activity profile for motif NKX2-2


Sorted Z-values histogram for motif NKX2-2

Sorted Z-values for motif NKX2-2



Network of associatons between targets according to the STRING database.



First level regulatory network of NKX2-2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr18_+_55888767 0.638 ENST00000431212.2
ENST00000586268.1
ENST00000587190.1
NEDD4L


neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase


chr4_+_74269956 0.621 ENST00000295897.4
ENST00000415165.2
ENST00000503124.1
ENST00000509063.1
ENST00000401494.3
ALB




albumin




chr12_-_54689532 0.599 ENST00000540264.2
ENST00000312156.4
NFE2

nuclear factor, erythroid 2

chr1_-_227505289 0.515 ENST00000366765.3
CDC42BPA
CDC42 binding protein kinase alpha (DMPK-like)
chrX_+_152953505 0.487 ENST00000253122.5
SLC6A8
solute carrier family 6 (neurotransmitter transporter), member 8
chr16_+_30212378 0.471 ENST00000569485.1
SULT1A3
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr16_+_30212050 0.462 ENST00000563322.1
SULT1A3
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr15_+_58702742 0.459 ENST00000356113.6
ENST00000414170.3
LIPC

lipase, hepatic

chr5_+_135394840 0.457 ENST00000503087.1
TGFBI
transforming growth factor, beta-induced, 68kDa
chr17_+_52978107 0.431 ENST00000445275.2
TOM1L1
target of myb1 (chicken)-like 1
chrX_+_115567767 0.405 ENST00000371900.4
SLC6A14
solute carrier family 6 (amino acid transporter), member 14
chr13_-_67802549 0.372 ENST00000328454.5
ENST00000377865.2
PCDH9

protocadherin 9

chr8_+_97597148 0.347 ENST00000521590.1
SDC2
syndecan 2
chr4_-_111563076 0.342 ENST00000354925.2
ENST00000511990.1
PITX2

paired-like homeodomain 2

chr17_+_53342311 0.330 ENST00000226067.5
HLF
hepatic leukemia factor
chr15_-_56209306 0.321 ENST00000506154.1
ENST00000338963.2
ENST00000508342.1
NEDD4


neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase


chr6_+_158733692 0.318 ENST00000367094.2
ENST00000367097.3
TULP4

tubby like protein 4

chr6_+_32121789 0.316 ENST00000437001.2
ENST00000375137.2
PPT2

palmitoyl-protein thioesterase 2

chr17_+_74372662 0.315 ENST00000591651.1
ENST00000545180.1
SPHK1

sphingosine kinase 1

chr9_-_99382065 0.300 ENST00000265659.2
ENST00000375241.1
ENST00000375236.1
CDC14B


cell division cycle 14B


chr2_+_170655322 0.294 ENST00000260956.4
ENST00000417292.1
SSB

Sjogren syndrome antigen B (autoantigen La)

chr1_+_54359854 0.294 ENST00000361921.3
ENST00000322679.6
ENST00000532493.1
ENST00000525202.1
ENST00000524406.1
ENST00000388876.3
DIO1





deiodinase, iodothyronine, type I





chr6_+_32121218 0.274 ENST00000414204.1
ENST00000361568.2
ENST00000395523.1
PPT2


palmitoyl-protein thioesterase 2


chr1_-_202936394 0.248 ENST00000367249.4
CYB5R1
cytochrome b5 reductase 1
chrX_-_154033661 0.244 ENST00000393531.1
MPP1
membrane protein, palmitoylated 1, 55kDa
chr12_-_28124903 0.241 ENST00000395872.1
ENST00000354417.3
ENST00000201015.4
PTHLH


parathyroid hormone-like hormone


chr5_+_108083517 0.237 ENST00000281092.4
ENST00000536402.1
FER

fer (fps/fes related) tyrosine kinase

chr5_+_82767487 0.237 ENST00000343200.5
ENST00000342785.4
VCAN

versican

chr8_+_77593448 0.234 ENST00000521891.2
ZFHX4
zinc finger homeobox 4
chr4_+_155484155 0.234 ENST00000509493.1
FGB
fibrinogen beta chain
chr3_-_114790179 0.233 ENST00000462705.1
ZBTB20
zinc finger and BTB domain containing 20
chr4_+_88720698 0.218 ENST00000226284.5
IBSP
integrin-binding sialoprotein
chr2_+_17721230 0.214 ENST00000457525.1
VSNL1
visinin-like 1
chr5_+_82767583 0.212 ENST00000512590.2
ENST00000513960.1
ENST00000513984.1
ENST00000502527.2
VCAN



versican



chr12_-_8803128 0.210 ENST00000543467.1
MFAP5
microfibrillar associated protein 5
chr13_-_36429763 0.208 ENST00000379893.1
DCLK1
doublecortin-like kinase 1
chr4_+_80584903 0.200 ENST00000506460.1
RP11-452C8.1
RP11-452C8.1
chr16_-_20556492 0.198 ENST00000568098.1
ACSM2B
acyl-CoA synthetase medium-chain family member 2B
chr3_-_196911002 0.187 ENST00000452595.1
DLG1
discs, large homolog 1 (Drosophila)
chr14_+_39734482 0.184 ENST00000554392.1
ENST00000555716.1
ENST00000341749.3
ENST00000557038.1
CTAGE5



CTAGE family, member 5



chr11_-_128894053 0.182 ENST00000392657.3
ARHGAP32
Rho GTPase activating protein 32
chr17_+_61086917 0.177 ENST00000424789.2
ENST00000389520.4
TANC2

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2

chr15_+_65843130 0.177 ENST00000569894.1
PTPLAD1
protein tyrosine phosphatase-like A domain containing 1
chr8_-_49833978 0.174 ENST00000020945.1
SNAI2
snail family zinc finger 2
chr9_+_131447342 0.173 ENST00000409104.3
SET
SET nuclear oncogene
chr11_-_72432950 0.172 ENST00000426523.1
ENST00000429686.1
ARAP1

ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1

chr8_-_141810634 0.170 ENST00000521986.1
ENST00000523539.1
ENST00000538769.1
PTK2


protein tyrosine kinase 2


chr7_+_2394445 0.164 ENST00000360876.4
ENST00000413917.1
ENST00000397011.2
EIF3B


eukaryotic translation initiation factor 3, subunit B


chr17_+_75315534 0.164 ENST00000590294.1
ENST00000329047.8
SEPT9

septin 9

chr8_+_77593474 0.163 ENST00000455469.2
ENST00000050961.6
ZFHX4

zinc finger homeobox 4

chr10_+_13203543 0.162 ENST00000378714.3
ENST00000479669.1
ENST00000484800.2
MCM10


minichromosome maintenance complex component 10


chr13_+_50656307 0.159 ENST00000378180.4
DLEU1
deleted in lymphocytic leukemia 1 (non-protein coding)
chr8_-_49834299 0.159 ENST00000396822.1
SNAI2
snail family zinc finger 2
chr3_-_33686743 0.157 ENST00000333778.6
ENST00000539981.1
CLASP2

cytoplasmic linker associated protein 2

chr11_-_77850629 0.156 ENST00000376156.3
ENST00000525870.1
ENST00000530454.1
ENST00000525755.1
ENST00000527099.1
ENST00000525761.1
ENST00000299626.5
ALG8






ALG8, alpha-1,3-glucosyltransferase






chr1_-_153363452 0.155 ENST00000368732.1
ENST00000368733.3
S100A8

S100 calcium binding protein A8

chr11_+_9406169 0.154 ENST00000379719.3
ENST00000527431.1
IPO7

importin 7

chr13_+_50570019 0.150 ENST00000442421.1
TRIM13
tripartite motif containing 13
chr19_-_14889349 0.150 ENST00000315576.3
ENST00000392967.2
ENST00000346057.1
ENST00000353876.1
ENST00000353005.1
EMR2




egf-like module containing, mucin-like, hormone receptor-like 2




chr4_+_155484103 0.148 ENST00000302068.4
FGB
fibrinogen beta chain
chr17_+_66521936 0.142 ENST00000592800.1
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha
chrX_-_70474910 0.140 ENST00000373988.1
ENST00000373998.1
ZMYM3

zinc finger, MYM-type 3

chr17_+_48823896 0.140 ENST00000511974.1
LUC7L3
LUC7-like 3 (S. cerevisiae)
chr22_-_36220420 0.139 ENST00000473487.2
RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr5_+_159848854 0.138 ENST00000517480.1
ENST00000520452.1
ENST00000393964.1
PTTG1


pituitary tumor-transforming 1


chr3_-_170744498 0.137 ENST00000382808.4
ENST00000314251.3
SLC2A2

solute carrier family 2 (facilitated glucose transporter), member 2

chrM_+_4431 0.131 ENST00000361453.3
MT-ND2
mitochondrially encoded NADH dehydrogenase 2
chr2_+_103035102 0.131 ENST00000264260.2
IL18RAP
interleukin 18 receptor accessory protein
chrX_-_32173579 0.129 ENST00000359836.1
ENST00000343523.2
ENST00000378707.3
ENST00000541735.1
ENST00000474231.1
DMD




dystrophin




chr5_+_148206156 0.126 ENST00000305988.4
ADRB2
adrenoceptor beta 2, surface
chr2_-_145275228 0.123 ENST00000427902.1
ENST00000409487.3
ENST00000470879.1
ENST00000435831.1
ZEB2



zinc finger E-box binding homeobox 2



chr12_-_102591604 0.122 ENST00000329406.4
PMCH
pro-melanin-concentrating hormone
chr4_+_41937131 0.120 ENST00000504986.1
ENST00000508448.1
ENST00000513702.1
ENST00000325094.5
TMEM33



transmembrane protein 33



chr5_-_78281603 0.120 ENST00000264914.4
ARSB
arylsulfatase B
chr8_-_18666360 0.120 ENST00000286485.8
PSD3
pleckstrin and Sec7 domain containing 3
chr4_-_76957214 0.118 ENST00000306621.3
CXCL11
chemokine (C-X-C motif) ligand 11
chr4_-_10686475 0.115 ENST00000226951.6
CLNK
cytokine-dependent hematopoietic cell linker
chr12_-_10978957 0.115 ENST00000240619.2
TAS2R10
taste receptor, type 2, member 10
chr9_+_92219919 0.114 ENST00000252506.6
ENST00000375769.1
GADD45G

growth arrest and DNA-damage-inducible, gamma

chr4_+_95376396 0.114 ENST00000508216.1
ENST00000514743.1
PDLIM5

PDZ and LIM domain 5

chrX_+_123095546 0.113 ENST00000371157.3
ENST00000371145.3
ENST00000371144.3
STAG2


stromal antigen 2


chr8_-_141774467 0.111 ENST00000520151.1
ENST00000519024.1
ENST00000519465.1
PTK2


protein tyrosine kinase 2


chr1_-_244006528 0.111 ENST00000336199.5
ENST00000263826.5
AKT3

v-akt murine thymoma viral oncogene homolog 3

chr1_-_36615065 0.107 ENST00000373166.3
ENST00000373159.1
ENST00000373162.1
TRAPPC3


trafficking protein particle complex 3


chr6_+_32936353 0.107 ENST00000374825.4
BRD2
bromodomain containing 2
chr3_-_123339343 0.106 ENST00000578202.1
MYLK
myosin light chain kinase
chr8_-_102181718 0.104 ENST00000565617.1
KB-1460A1.5
KB-1460A1.5
chr20_-_13765526 0.102 ENST00000202816.1
ESF1
ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)
chr12_+_41831485 0.101 ENST00000539469.2
ENST00000298919.7
PDZRN4

PDZ domain containing ring finger 4

chr19_-_18433910 0.100 ENST00000594828.3
ENST00000593829.1
LSM4

LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)

chr10_+_73156664 0.100 ENST00000398809.4
ENST00000398842.3
ENST00000461841.3
ENST00000299366.7
CDH23



cadherin-related 23



chr3_-_123339418 0.099 ENST00000583087.1
MYLK
myosin light chain kinase
chrX_+_47092314 0.099 ENST00000218348.3
USP11
ubiquitin specific peptidase 11
chr1_+_117963209 0.098 ENST00000449370.2
MAN1A2
mannosidase, alpha, class 1A, member 2
chr16_+_10837643 0.097 ENST00000574334.1
ENST00000283027.5
ENST00000433392.2
NUBP1


nucleotide binding protein 1


chr1_-_36615051 0.095 ENST00000373163.1
TRAPPC3
trafficking protein particle complex 3
chr5_-_179047881 0.095 ENST00000521173.1
HNRNPH1
heterogeneous nuclear ribonucleoprotein H1 (H)
chr11_-_72433346 0.095 ENST00000334211.8
ARAP1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr2_+_120436733 0.095 ENST00000401466.1
ENST00000424086.1
ENST00000272521.6
TMEM177


transmembrane protein 177


chr2_-_24270217 0.094 ENST00000295148.4
ENST00000406895.3
C2orf44

chromosome 2 open reading frame 44

chr5_+_167718604 0.092 ENST00000265293.4
WWC1
WW and C2 domain containing 1
chr8_-_121457332 0.091 ENST00000518918.1
MRPL13
mitochondrial ribosomal protein L13
chrM_+_12331 0.090 ENST00000361567.2
MT-ND5
mitochondrially encoded NADH dehydrogenase 5
chr15_-_56757329 0.090 ENST00000260453.3
MNS1
meiosis-specific nuclear structural 1
chr22_-_42086477 0.089 ENST00000402458.1
NHP2L1
NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)
chr5_+_159848807 0.089 ENST00000352433.5
PTTG1
pituitary tumor-transforming 1
chr8_+_110552337 0.089 ENST00000337573.5
EBAG9
estrogen receptor binding site associated, antigen, 9
chr5_+_125758865 0.089 ENST00000542322.1
ENST00000544396.1
GRAMD3

GRAM domain containing 3

chr12_-_71551652 0.085 ENST00000546561.1
TSPAN8
tetraspanin 8
chr1_+_202431859 0.084 ENST00000391959.3
ENST00000367270.4
PPP1R12B

protein phosphatase 1, regulatory subunit 12B

chr21_-_36421401 0.084 ENST00000486278.2
RUNX1
runt-related transcription factor 1
chr2_-_27558270 0.079 ENST00000454704.1
GTF3C2
general transcription factor IIIC, polypeptide 2, beta 110kDa
chr7_+_102715315 0.078 ENST00000428183.2
ENST00000323716.3
ENST00000441711.2
ENST00000454559.1
ENST00000425331.1
ENST00000541300.1
ARMC10





armadillo repeat containing 10





chr5_-_11588907 0.077 ENST00000513598.1
ENST00000503622.1
CTNND2

catenin (cadherin-associated protein), delta 2

chr5_-_58335281 0.077 ENST00000358923.6
PDE4D
phosphodiesterase 4D, cAMP-specific
chr12_+_14572070 0.077 ENST00000545769.1
ENST00000428217.2
ENST00000396279.2
ENST00000542514.1
ENST00000536279.1
ATF7IP




activating transcription factor 7 interacting protein




chr1_+_15272271 0.076 ENST00000400797.3
KAZN
kazrin, periplakin interacting protein
chr15_-_42840961 0.075 ENST00000563454.1
ENST00000397130.3
ENST00000570160.1
ENST00000323443.2
LRRC57



leucine rich repeat containing 57



chr6_-_11779014 0.075 ENST00000229583.5
ADTRP
androgen-dependent TFPI-regulating protein
chr5_+_125758813 0.074 ENST00000285689.3
ENST00000515200.1
GRAMD3

GRAM domain containing 3

chr17_-_2966901 0.074 ENST00000575751.1
OR1D5
olfactory receptor, family 1, subfamily D, member 5
chr7_-_22233442 0.073 ENST00000401957.2
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr4_-_110723335 0.073 ENST00000394634.2
CFI
complement factor I
chr6_-_150067632 0.072 ENST00000460354.2
ENST00000367404.4
ENST00000543637.1
NUP43


nucleoporin 43kDa


chr18_-_60985914 0.069 ENST00000589955.1
BCL2
B-cell CLL/lymphoma 2
chr20_+_30697510 0.068 ENST00000217315.5
TM9SF4
transmembrane 9 superfamily protein member 4
chr14_-_50154921 0.068 ENST00000553805.2
ENST00000554396.1
ENST00000216367.5
ENST00000539565.2
POLE2



polymerase (DNA directed), epsilon 2, accessory subunit



chr17_+_48823975 0.066 ENST00000513969.1
ENST00000503728.1
LUC7L3

LUC7-like 3 (S. cerevisiae)

chr6_+_44355257 0.064 ENST00000371477.3
CDC5L
cell division cycle 5-like
chr16_+_22501658 0.064 ENST00000415833.2
NPIPB5
nuclear pore complex interacting protein family, member B5
chr11_-_11374904 0.063 ENST00000528848.2
CSNK2A3
casein kinase 2, alpha 3 polypeptide
chr17_+_7591639 0.063 ENST00000396463.2
WRAP53
WD repeat containing, antisense to TP53
chr6_-_150067696 0.063 ENST00000340413.2
ENST00000367403.3
NUP43

nucleoporin 43kDa

chr20_+_30697298 0.062 ENST00000398022.2
TM9SF4
transmembrane 9 superfamily protein member 4
chr2_+_162087577 0.062 ENST00000439442.1
TANK
TRAF family member-associated NFKB activator
chr1_+_150898812 0.061 ENST00000271640.5
ENST00000448029.1
ENST00000368962.2
ENST00000534805.1
ENST00000368969.4
ENST00000368963.1
ENST00000498193.1
SETDB1






SET domain, bifurcated 1






chr8_-_133637624 0.061 ENST00000522789.1
LRRC6
leucine rich repeat containing 6
chr19_+_47634039 0.059 ENST00000597808.1
ENST00000413379.3
ENST00000600706.1
ENST00000540850.1
ENST00000598840.1
ENST00000600753.1
ENST00000270225.7
ENST00000392776.3
SAE1







SUMO1 activating enzyme subunit 1







chr6_+_45296391 0.058 ENST00000371436.6
ENST00000576263.1
RUNX2

runt-related transcription factor 2

chr8_-_22526597 0.058 ENST00000519513.1
ENST00000276416.6
ENST00000520292.1
ENST00000522268.1
BIN3



bridging integrator 3



chr1_-_31538517 0.058 ENST00000440538.2
ENST00000423018.2
ENST00000424085.2
ENST00000426105.2
ENST00000257075.5
ENST00000373747.3
ENST00000525843.1
ENST00000373742.2
PUM1







pumilio RNA-binding family member 1







chr14_+_39703084 0.056 ENST00000553728.1
RP11-407N17.3
cTAGE family member 5 isoform 4
chr7_-_107443652 0.055 ENST00000340010.5
ENST00000422236.2
ENST00000453332.1
SLC26A3


solute carrier family 26 (anion exchanger), member 3


chr19_-_39881669 0.055 ENST00000221266.7
PAF1
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
chr5_+_40909354 0.055 ENST00000313164.9
C7
complement component 7
chr13_+_25875785 0.055 ENST00000381747.3
NUPL1
nucleoporin like 1
chr18_-_60986613 0.054 ENST00000444484.1
BCL2
B-cell CLL/lymphoma 2
chr9_+_123970052 0.053 ENST00000373823.3
GSN
gelsolin
chr12_+_52056548 0.053 ENST00000545061.1
ENST00000355133.3
SCN8A

sodium channel, voltage gated, type VIII, alpha subunit

chr2_+_162272605 0.052 ENST00000389554.3
TBR1
T-box, brain, 1
chr13_+_25875662 0.052 ENST00000381736.3
ENST00000463407.1
ENST00000381718.3
NUPL1


nucleoporin like 1


chr5_-_58652788 0.051 ENST00000405755.2
PDE4D
phosphodiesterase 4D, cAMP-specific
chr13_+_102104952 0.051 ENST00000376180.3
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr20_+_56964169 0.051 ENST00000475243.1
VAPB
VAMP (vesicle-associated membrane protein)-associated protein B and C
chr7_-_22234381 0.050 ENST00000458533.1
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr8_+_110552831 0.050 ENST00000530629.1
EBAG9
estrogen receptor binding site associated, antigen, 9
chr14_-_25078864 0.050 ENST00000216338.4
ENST00000557220.2
ENST00000382548.4
GZMH


granzyme H (cathepsin G-like 2, protein h-CCPX)


chr2_+_171034646 0.049 ENST00000409044.3
ENST00000408978.4
MYO3B

myosin IIIB

chr2_+_152266392 0.049 ENST00000444746.2
ENST00000453091.2
ENST00000428287.2
ENST00000433166.2
ENST00000420714.3
ENST00000243326.5
ENST00000414861.2
RIF1






RAP1 interacting factor homolog (yeast)






chr2_-_217724767 0.049 ENST00000236979.2
TNP1
transition protein 1 (during histone to protamine replacement)
chr1_+_224301787 0.047 ENST00000366862.5
ENST00000424254.2
FBXO28

F-box protein 28

chr6_+_20534672 0.047 ENST00000274695.4
ENST00000378624.4
CDKAL1

CDK5 regulatory subunit associated protein 1-like 1

chr17_+_38171681 0.047 ENST00000225474.2
ENST00000331769.2
ENST00000394148.3
ENST00000577675.1
CSF3



colony stimulating factor 3 (granulocyte)



chr17_-_42143963 0.044 ENST00000585388.1
ENST00000293406.3
LSM12

LSM12 homolog (S. cerevisiae)

chr1_+_171217622 0.044 ENST00000433267.1
ENST00000367750.3
FMO1

flavin containing monooxygenase 1

chr7_+_32535060 0.044 ENST00000318709.4
ENST00000409301.1
ENST00000404479.1
AVL9


AVL9 homolog (S. cerevisiase)


chr1_-_160231451 0.043 ENST00000495887.1
DCAF8
DDB1 and CUL4 associated factor 8
chr18_+_9103957 0.043 ENST00000400033.1
NDUFV2
NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa
chr1_+_211433275 0.043 ENST00000367005.4
RCOR3
REST corepressor 3
chr17_+_7591747 0.042 ENST00000534050.1
WRAP53
WD repeat containing, antisense to TP53
chr4_+_113739244 0.042 ENST00000503271.1
ENST00000503423.1
ENST00000506722.1
ANK2


ankyrin 2, neuronal


chr9_-_86593238 0.042 ENST00000351839.3
HNRNPK
heterogeneous nuclear ribonucleoprotein K
chrX_-_70473957 0.042 ENST00000373984.3
ENST00000314425.5
ENST00000373982.1
ZMYM3


zinc finger, MYM-type 3


chr7_+_93535866 0.041 ENST00000429473.1
ENST00000430875.1
ENST00000428834.1
GNGT1


guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1


chr8_-_122653630 0.040 ENST00000303924.4
HAS2
hyaluronan synthase 2
chr17_+_38171614 0.039 ENST00000583218.1
ENST00000394149.3
CSF3

colony stimulating factor 3 (granulocyte)

chr8_-_121457608 0.039 ENST00000306185.3
MRPL13
mitochondrial ribosomal protein L13
chr5_-_11589131 0.039 ENST00000511377.1
CTNND2
catenin (cadherin-associated protein), delta 2
chr5_-_98262240 0.039 ENST00000284049.3
CHD1
chromodomain helicase DNA binding protein 1
chr9_+_71944241 0.038 ENST00000257515.8
FAM189A2
family with sequence similarity 189, member A2
chr2_-_40739501 0.037 ENST00000403092.1
ENST00000402441.1
ENST00000448531.1
SLC8A1


solute carrier family 8 (sodium/calcium exchanger), member 1


chr4_+_144303093 0.036 ENST00000505913.1
GAB1
GRB2-associated binding protein 1
chr6_+_45296048 0.036 ENST00000465038.2
ENST00000352853.5
ENST00000541979.1
ENST00000371438.1
RUNX2



runt-related transcription factor 2



chr9_+_37753795 0.035 ENST00000377753.2
ENST00000537911.1
ENST00000377754.2
ENST00000297994.3
TRMT10B



tRNA methyltransferase 10 homolog B (S. cerevisiae)



chrX_-_153363188 0.035 ENST00000303391.6
MECP2
methyl CpG binding protein 2 (Rett syndrome)
chr3_-_113897899 0.035 ENST00000383673.2
ENST00000295881.7
DRD3

dopamine receptor D3

chr5_+_140552218 0.034 ENST00000231137.3
PCDHB7
protocadherin beta 7
chr4_+_95679072 0.034 ENST00000515059.1
BMPR1B
bone morphogenetic protein receptor, type IB
chr6_+_55039050 0.034 ENST00000370862.3
HCRTR2
hypocretin (orexin) receptor 2
chr7_+_93535817 0.034 ENST00000248572.5
GNGT1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr12_-_120315074 0.033 ENST00000261833.7
ENST00000392521.2
CIT

citron (rho-interacting, serine/threonine kinase 21)

chrX_-_130037198 0.033 ENST00000370935.1
ENST00000338144.3
ENST00000394363.1
ENOX2


ecto-NOX disulfide-thiol exchanger 2


chr8_-_134072593 0.033 ENST00000427060.2
SLA
Src-like-adaptor
chr1_+_50459990 0.033 ENST00000448346.1
AL645730.2
AL645730.2
chr1_-_110155671 0.032 ENST00000351050.3
GNAT2
guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
chr5_+_34757309 0.032 ENST00000397449.1
RAI14
retinoic acid induced 14
chr3_+_189507523 0.032 ENST00000437221.1
ENST00000392463.2
ENST00000392461.3
ENST00000449992.1
ENST00000456148.1
TP63




tumor protein p63




chr1_-_115259337 0.032 ENST00000369535.4
NRAS
neuroblastoma RAS viral (v-ras) oncogene homolog
chr5_+_140602904 0.032 ENST00000515856.2
ENST00000239449.4
PCDHB14

protocadherin beta 14

chr9_-_95166841 0.031 ENST00000262551.4
OGN
osteoglycin

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0001907 cytolysis by symbiont of host cells(GO:0001897) killing by symbiont of host cells(GO:0001907) hemolysis by symbiont of host erythrocytes(GO:0019836) disruption by symbiont of host cell(GO:0044004) hemolysis in other organism(GO:0044179) positive regulation of circadian sleep/wake cycle, non-REM sleep(GO:0046010) cytolysis in other organism(GO:0051715) cytolysis in other organism involved in symbiotic interaction(GO:0051801) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.1 0.1 GO:0045938 positive regulation of circadian sleep/wake cycle, sleep(GO:0045938)
0.1 1.0 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.1 0.3 GO:0046521 sphingoid catabolic process(GO:0046521)
0.1 0.4 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.1 0.3 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037) actin filament reorganization(GO:0090527)
0.1 0.8 GO:0031498 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.1 0.2 GO:0060649 nipple development(GO:0060618) mammary gland bud elongation(GO:0060649) nipple morphogenesis(GO:0060658) nipple sheath formation(GO:0060659)
0.1 0.3 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.1 0.5 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.9 GO:0009812 flavonoid metabolic process(GO:0009812)
0.0 0.5 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.1 GO:0003011 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025) diaphragm contraction(GO:0002086) involuntary skeletal muscle contraction(GO:0003011) regulation of skeletal muscle tissue growth(GO:0048631)
0.0 0.1 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 0.3 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 0.1 GO:0046671 regulation of nitrogen utilization(GO:0006808) positive regulation of neuron maturation(GO:0014042) nitrogen utilization(GO:0019740) cochlear nucleus development(GO:0021747) negative regulation of cellular pH reduction(GO:0032848) glial cell apoptotic process(GO:0034349) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671) positive regulation of cell maturation(GO:1903431)
0.0 0.1 GO:0035330 regulation of hippo signaling(GO:0035330)
0.0 0.2 GO:0060414 aorta development(GO:0035904) aorta morphogenesis(GO:0035909) aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.1 GO:0032203 telomere formation via telomerase(GO:0032203)
0.0 0.2 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.2 GO:1902622 regulation of neutrophil chemotaxis(GO:0090022) regulation of neutrophil migration(GO:1902622)
0.0 0.1 GO:0000917 barrier septum assembly(GO:0000917) cell septum assembly(GO:0090529) mitotic cytokinetic process(GO:1902410)
0.0 0.3 GO:0006400 tRNA modification(GO:0006400)
0.0 0.3 GO:0031000 response to caffeine(GO:0031000)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.1 GO:0097061 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0 0.4 GO:0008347 glial cell migration(GO:0008347)
0.0 0.1 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.1 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.5 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.4 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.3 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.1 GO:0042797 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0 0.3 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.0 0.0 GO:0072369 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716) regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.0 0.1 GO:0051597 response to methylmercury(GO:0051597)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.4 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.1 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.2 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.3 GO:0032420 stereocilium(GO:0032420)
0.0 0.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.5 GO:0031526 brush border membrane(GO:0031526)
0.0 0.2 GO:0001527 microfibril(GO:0001527)
0.0 0.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.5 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.0 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.2 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 0.6 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.9 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 0.6 GO:0015643 toxic substance binding(GO:0015643)
0.1 0.3 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 0.2 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.3 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.1 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.9 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.5 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.1 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.2 GO:0008107 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0 0.1 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.2 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.6 GO:0050699 WW domain binding(GO:0050699)
0.0 0.2 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.0 0.4 GO:0043499 obsolete eukaryotic cell surface binding(GO:0043499)
0.0 0.1 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.3 GO:0000049 tRNA binding(GO:0000049)
0.0 0.1 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.1 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.5 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0008527 taste receptor activity(GO:0008527)
0.0 0.2 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.1 GO:0042805 actinin binding(GO:0042805)
0.0 0.2 GO:0045295 gamma-catenin binding(GO:0045295)