Motif ID: NKX2-5

Z-value: 0.695


Transcription factors associated with NKX2-5:

Gene SymbolEntrez IDGene Name
NKX2-5 ENSG00000183072.9 NKX2-5



Activity profile for motif NKX2-5.

activity profile for motif NKX2-5


Sorted Z-values histogram for motif NKX2-5

Sorted Z-values for motif NKX2-5



Network of associatons between targets according to the STRING database.



First level regulatory network of NKX2-5

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_-_149792295 0.959 ENST00000518797.1
ENST00000524315.1
ENST00000009530.7
ENST00000377795.3
CD74



CD74 molecule, major histocompatibility complex, class II invariant chain



chr14_-_106406090 0.953 ENST00000390593.2
IGHV6-1
immunoglobulin heavy variable 6-1
chr17_-_29641104 0.854 ENST00000577894.1
ENST00000330927.4
EVI2B

ecotropic viral integration site 2B

chr17_-_29641084 0.688 ENST00000544462.1
EVI2B
ecotropic viral integration site 2B
chr14_-_106963409 0.662 ENST00000390621.2
IGHV1-45
immunoglobulin heavy variable 1-45
chr12_+_113354341 0.631 ENST00000553152.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr7_+_99775366 0.599 ENST00000394018.2
ENST00000416412.1
STAG3

stromal antigen 3

chr7_+_99775520 0.577 ENST00000317296.5
ENST00000422690.1
ENST00000439782.1
STAG3


stromal antigen 3


chr13_-_41240717 0.546 ENST00000379561.5
FOXO1
forkhead box O1
chr5_+_75699040 0.530 ENST00000274364.6
IQGAP2
IQ motif containing GTPase activating protein 2
chr15_+_81589254 0.513 ENST00000394652.2
IL16
interleukin 16
chr2_-_175499294 0.502 ENST00000392547.2
WIPF1
WAS/WASL interacting protein family, member 1
chr8_-_120651020 0.460 ENST00000522826.1
ENST00000520066.1
ENST00000259486.6
ENST00000075322.6
ENPP2



ectonucleotide pyrophosphatase/phosphodiesterase 2



chr17_+_26646175 0.438 ENST00000583381.1
ENST00000582113.1
ENST00000582384.1
TMEM97


transmembrane protein 97


chr1_+_186798073 0.415 ENST00000367466.3
ENST00000442353.2
PLA2G4A

phospholipase A2, group IVA (cytosolic, calcium-dependent)

chr17_+_26646121 0.390 ENST00000226230.6
TMEM97
transmembrane protein 97
chr7_-_37488834 0.385 ENST00000310758.4
ELMO1
engulfment and cell motility 1
chr3_-_15374659 0.338 ENST00000426925.1
SH3BP5
SH3-domain binding protein 5 (BTK-associated)
chr17_+_48624450 0.327 ENST00000006658.6
ENST00000356488.4
ENST00000393244.3
SPATA20


spermatogenesis associated 20


chr5_-_171615315 0.317 ENST00000176763.5
STK10
serine/threonine kinase 10
chr5_+_122110691 0.303 ENST00000379516.2
ENST00000505934.1
ENST00000514949.1
SNX2


sorting nexin 2


chr22_+_40322595 0.291 ENST00000420971.1
ENST00000544756.1
GRAP2

GRB2-related adaptor protein 2

chr22_+_40322623 0.290 ENST00000399090.2
GRAP2
GRB2-related adaptor protein 2
chr11_+_108093839 0.279 ENST00000452508.2
ATM
ataxia telangiectasia mutated
chr3_-_111314230 0.276 ENST00000317012.4
ZBED2
zinc finger, BED-type containing 2
chr9_-_34048873 0.274 ENST00000449054.1
ENST00000379239.4
ENST00000539807.1
ENST00000379238.1
ENST00000418786.2
ENST00000360802.1
ENST00000412543.1
UBAP2






ubiquitin associated protein 2






chr12_+_93772402 0.270 ENST00000546925.1
NUDT4
nudix (nucleoside diphosphate linked moiety X)-type motif 4
chr1_-_55352834 0.249 ENST00000371269.3
DHCR24
24-dehydrocholesterol reductase
chrX_-_154299501 0.233 ENST00000369484.3
ENST00000369476.3
CMC4
MTCP1
C-x(9)-C motif containing 4
mature T-cell proliferation 1
chr4_+_2470664 0.231 ENST00000314289.8
ENST00000541204.1
ENST00000502316.1
ENST00000507247.1
ENST00000509258.1
ENST00000511859.1
RNF4





ring finger protein 4





chr18_+_42260861 0.221 ENST00000282030.5
SETBP1
SET binding protein 1
chr1_+_27153173 0.215 ENST00000374142.4
ZDHHC18
zinc finger, DHHC-type containing 18
chr3_-_56717246 0.211 ENST00000355628.5
FAM208A
family with sequence similarity 208, member A
chr3_-_11685345 0.210 ENST00000430365.2
VGLL4
vestigial like 4 (Drosophila)
chr5_-_76788317 0.202 ENST00000296679.4
WDR41
WD repeat domain 41
chr15_+_42841008 0.195 ENST00000260372.3
ENST00000568876.1
ENST00000568846.2
ENST00000562398.1
HAUS2



HAUS augmin-like complex, subunit 2



chr1_-_22109682 0.190 ENST00000400301.1
ENST00000532737.1
USP48

ubiquitin specific peptidase 48

chr16_+_77233294 0.184 ENST00000378644.4
SYCE1L
synaptonemal complex central element protein 1-like
chr11_+_64879317 0.182 ENST00000526809.1
ENST00000279263.7
ENST00000524986.1
ENST00000534371.1
ENST00000540748.1
ENST00000525385.1
ENST00000345348.5
ENST00000531321.1
ENST00000529414.1
ENST00000526085.1
ENST00000530750.1
TM7SF2










transmembrane 7 superfamily member 2










chr20_+_57226284 0.170 ENST00000458280.1
ENST00000355957.5
ENST00000361770.5
ENST00000312283.8
ENST00000412911.1
ENST00000359617.4
ENST00000371141.4
STX16






syntaxin 16






chr10_+_76586348 0.169 ENST00000372724.1
ENST00000287239.4
ENST00000372714.1
KAT6B


K(lysine) acetyltransferase 6B


chr12_+_56360550 0.168 ENST00000266970.4
CDK2
cyclin-dependent kinase 2
chr9_-_117692697 0.165 ENST00000223795.2
TNFSF8
tumor necrosis factor (ligand) superfamily, member 8
chr16_+_33006369 0.162 ENST00000425181.3
IGHV3OR16-10
immunoglobulin heavy variable 3/OR16-10 (non-functional)
chr20_+_57226841 0.160 ENST00000358029.4
ENST00000361830.3
STX16

syntaxin 16

chr19_+_5681153 0.150 ENST00000577222.1
ENST00000579559.1
RPL36
HSD11B1L
ribosomal protein L36
hydroxysteroid (11-beta) dehydrogenase 1-like
chr11_+_18417813 0.150 ENST00000540430.1
ENST00000379412.5
LDHA

lactate dehydrogenase A

chr6_-_41715128 0.143 ENST00000356667.4
ENST00000373025.3
ENST00000425343.2
PGC


progastricsin (pepsinogen C)


chr17_+_53342311 0.141 ENST00000226067.5
HLF
hepatic leukemia factor
chr10_+_73156664 0.134 ENST00000398809.4
ENST00000398842.3
ENST00000461841.3
ENST00000299366.7
CDH23



cadherin-related 23



chr7_-_87342564 0.133 ENST00000265724.3
ENST00000416177.1
ABCB1

ATP-binding cassette, sub-family B (MDR/TAP), member 1

chr17_-_29624343 0.126 ENST00000247271.4
OMG
oligodendrocyte myelin glycoprotein
chr3_+_42201653 0.120 ENST00000341421.3
ENST00000396175.1
TRAK1

trafficking protein, kinesin binding 1

chr12_+_93772326 0.119 ENST00000550056.1
ENST00000549992.1
ENST00000548662.1
ENST00000547014.1
NUDT4



nudix (nucleoside diphosphate linked moiety X)-type motif 4



chrX_-_14047996 0.118 ENST00000380523.4
ENST00000398355.3
GEMIN8

gem (nuclear organelle) associated protein 8

chrX_+_115567767 0.117 ENST00000371900.4
SLC6A14
solute carrier family 6 (amino acid transporter), member 14
chr8_+_76452097 0.117 ENST00000396423.2
HNF4G
hepatocyte nuclear factor 4, gamma
chr8_-_95220775 0.113 ENST00000441892.2
ENST00000521491.1
ENST00000027335.3
CDH17


cadherin 17, LI cadherin (liver-intestine)


chr7_-_81399355 0.112 ENST00000457544.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr19_+_5681011 0.111 ENST00000581893.1
ENST00000411793.2
ENST00000301382.4
ENST00000581773.1
ENST00000423665.2
ENST00000583928.1
ENST00000342970.2
ENST00000422535.2
ENST00000581521.1
ENST00000339423.2
HSD11B1L









hydroxysteroid (11-beta) dehydrogenase 1-like









chr2_+_201997492 0.111 ENST00000494258.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr15_-_74726283 0.108 ENST00000543145.2
SEMA7A
semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
chr19_+_1026566 0.107 ENST00000348419.3
ENST00000565096.2
ENST00000562958.2
ENST00000562075.2
ENST00000607102.1
CNN2




calponin 2




chr11_+_43702236 0.107 ENST00000531185.1
ENST00000278353.4
HSD17B12

hydroxysteroid (17-beta) dehydrogenase 12

chr22_-_38577782 0.105 ENST00000430886.1
ENST00000332509.3
ENST00000447598.2
ENST00000435484.1
ENST00000402064.1
ENST00000436218.1
PLA2G6





phospholipase A2, group VI (cytosolic, calcium-independent)





chr7_-_81399438 0.104 ENST00000222390.5
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr7_-_81399329 0.102 ENST00000453411.1
ENST00000444829.2
HGF

hepatocyte growth factor (hepapoietin A; scatter factor)

chr10_+_133753533 0.101 ENST00000422256.2
PPP2R2D
protein phosphatase 2, regulatory subunit B, delta
chr17_+_75447326 0.100 ENST00000591088.1
SEPT9
septin 9
chr12_-_371994 0.100 ENST00000343164.4
ENST00000436453.1
ENST00000445055.2
ENST00000546319.1
SLC6A13



solute carrier family 6 (neurotransmitter transporter), member 13



chr22_-_38577731 0.093 ENST00000335539.3
PLA2G6
phospholipase A2, group VI (cytosolic, calcium-independent)
chr11_-_19223523 0.093 ENST00000265968.3
CSRP3
cysteine and glycine-rich protein 3 (cardiac LIM protein)
chr15_-_42840961 0.093 ENST00000563454.1
ENST00000397130.3
ENST00000570160.1
ENST00000323443.2
LRRC57



leucine rich repeat containing 57



chr17_+_29421987 0.091 ENST00000431387.4
NF1
neurofibromin 1
chr7_+_129007964 0.090 ENST00000460109.1
ENST00000474594.1
ENST00000446212.1
AHCYL2


adenosylhomocysteinase-like 2


chr17_-_3500392 0.086 ENST00000571088.1
ENST00000174621.6
TRPV1

transient receptor potential cation channel, subfamily V, member 1

chr7_-_81399411 0.085 ENST00000423064.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr10_-_101841588 0.085 ENST00000370418.3
CPN1
carboxypeptidase N, polypeptide 1
chr15_+_42696992 0.084 ENST00000561817.1
CAPN3
calpain 3, (p94)
chr4_+_81118647 0.082 ENST00000415738.2
PRDM8
PR domain containing 8
chr8_+_48873453 0.081 ENST00000523944.1
MCM4
minichromosome maintenance complex component 4
chr6_-_112115074 0.080 ENST00000368667.2
FYN
FYN oncogene related to SRC, FGR, YES
chr15_-_81282133 0.079 ENST00000261758.4
MESDC2
mesoderm development candidate 2
chr17_+_40811283 0.078 ENST00000251412.7
TUBG2
tubulin, gamma 2
chr1_-_11907829 0.076 ENST00000376480.3
NPPA
natriuretic peptide A
chr15_+_42697018 0.075 ENST00000397204.4
CAPN3
calpain 3, (p94)
chr2_-_220041617 0.074 ENST00000451647.1
ENST00000360507.5
CNPPD1

cyclin Pas1/PHO80 domain containing 1

chr18_+_61575200 0.074 ENST00000238508.3
SERPINB10
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr19_-_5680499 0.073 ENST00000587589.1
C19orf70
chromosome 19 open reading frame 70
chr8_+_48873479 0.073 ENST00000262105.2
MCM4
minichromosome maintenance complex component 4
chr8_+_132916318 0.072 ENST00000254624.5
ENST00000522709.1
EFR3A

EFR3 homolog A (S. cerevisiae)

chr13_+_25670268 0.070 ENST00000281589.3
PABPC3
poly(A) binding protein, cytoplasmic 3
chr19_+_16999654 0.069 ENST00000248076.3
F2RL3
coagulation factor II (thrombin) receptor-like 3
chr16_+_8814563 0.068 ENST00000425191.2
ENST00000569156.1
ABAT

4-aminobutyrate aminotransferase

chr4_+_113970772 0.068 ENST00000504454.1
ENST00000394537.3
ENST00000357077.4
ENST00000264366.6
ANK2



ankyrin 2, neuronal



chr3_-_187388173 0.067 ENST00000287641.3
SST
somatostatin
chr7_+_142457315 0.067 ENST00000486171.1
ENST00000311737.7
PRSS1

protease, serine, 1 (trypsin 1)

chr5_+_140345820 0.066 ENST00000289269.5
PCDHAC2
protocadherin alpha subfamily C, 2
chr12_-_49259643 0.065 ENST00000309739.5
RND1
Rho family GTPase 1
chr9_+_33265011 0.059 ENST00000419016.2
CHMP5
charged multivesicular body protein 5
chr9_+_118950325 0.059 ENST00000534838.1
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr21_+_44313375 0.058 ENST00000354250.2
ENST00000340344.4
NDUFV3

NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa

chr1_+_211433275 0.057 ENST00000367005.4
RCOR3
REST corepressor 3
chr15_+_42696954 0.054 ENST00000337571.4
ENST00000569136.1
CAPN3

calpain 3, (p94)

chr3_+_23847394 0.052 ENST00000306627.3
UBE2E1
ubiquitin-conjugating enzyme E2E 1
chr17_-_7493390 0.051 ENST00000538513.2
ENST00000570788.1
ENST00000250055.2
SOX15


SRY (sex determining region Y)-box 15


chr3_+_45984947 0.050 ENST00000304552.4
CXCR6
chemokine (C-X-C motif) receptor 6
chr20_-_44485835 0.050 ENST00000457981.1
ENST00000426915.1
ENST00000217455.4
ACOT8


acyl-CoA thioesterase 8


chr8_-_10588010 0.048 ENST00000304501.1
SOX7
SRY (sex determining region Y)-box 7
chr7_-_128415844 0.046 ENST00000249389.2
OPN1SW
opsin 1 (cone pigments), short-wave-sensitive
chr17_+_38333263 0.044 ENST00000456989.2
ENST00000543876.1
ENST00000544503.1
ENST00000264644.6
ENST00000538884.1
RAPGEFL1




Rap guanine nucleotide exchange factor (GEF)-like 1




chr10_+_75504105 0.041 ENST00000535742.1
ENST00000546025.1
ENST00000345254.4
ENST00000540668.1
ENST00000339365.2
ENST00000411652.2
SEC24C





SEC24 family member C





chr1_-_113498943 0.039 ENST00000369626.3
SLC16A1
solute carrier family 16 (monocarboxylate transporter), member 1
chr1_-_115259337 0.033 ENST00000369535.4
NRAS
neuroblastoma RAS viral (v-ras) oncogene homolog
chr17_+_58755184 0.031 ENST00000589222.1
ENST00000407086.3
ENST00000390652.5
BCAS3


breast carcinoma amplified sequence 3


chr12_+_14518598 0.031 ENST00000261168.4
ENST00000538511.1
ENST00000545723.1
ENST00000543189.1
ENST00000536444.1
ATF7IP




activating transcription factor 7 interacting protein




chr4_-_74853897 0.029 ENST00000296028.3
PPBP
pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
chr6_-_94129244 0.028 ENST00000369303.4
ENST00000369297.1
EPHA7

EPH receptor A7

chr22_-_50524298 0.027 ENST00000311597.5
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr11_-_108464321 0.027 ENST00000265843.4
EXPH5
exophilin 5
chr11_+_120973375 0.027 ENST00000264037.2
TECTA
tectorin alpha
chr22_-_50523760 0.027 ENST00000395876.2
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr2_-_96874553 0.027 ENST00000337288.5
ENST00000443962.1
STARD7

StAR-related lipid transfer (START) domain containing 7

chr2_+_152214098 0.026 ENST00000243347.3
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr2_-_201936302 0.024 ENST00000453765.1
ENST00000452799.1
ENST00000446678.1
ENST00000418596.3
FAM126B



family with sequence similarity 126, member B



chr1_+_32671236 0.023 ENST00000537469.1
ENST00000291358.6
IQCC

IQ motif containing C

chr2_+_219646462 0.023 ENST00000258415.4
CYP27A1
cytochrome P450, family 27, subfamily A, polypeptide 1
chr9_+_33264861 0.023 ENST00000223500.8
CHMP5
charged multivesicular body protein 5
chr6_+_31916733 0.023 ENST00000483004.1
CFB
complement factor B
chr13_-_95364389 0.022 ENST00000376945.2
SOX21
SRY (sex determining region Y)-box 21
chr3_+_23847432 0.022 ENST00000346855.3
UBE2E1
ubiquitin-conjugating enzyme E2E 1
chr10_-_81320151 0.022 ENST00000372325.2
ENST00000372327.5
ENST00000417041.1
SFTPA2


surfactant protein A2


chr11_+_76813886 0.020 ENST00000529803.1
OMP
olfactory marker protein
chr11_-_108464465 0.020 ENST00000525344.1
EXPH5
exophilin 5
chr2_-_27545431 0.019 ENST00000233545.2
MPV17
MpV17 mitochondrial inner membrane protein
chr2_+_136289030 0.018 ENST00000409478.1
ENST00000264160.4
ENST00000329971.3
ENST00000438014.1
R3HDM1



R3H domain containing 1



chr17_+_27055798 0.018 ENST00000268766.6
NEK8
NIMA-related kinase 8
chr9_+_116263639 0.017 ENST00000343817.5
RGS3
regulator of G-protein signaling 3
chr3_+_108321623 0.015 ENST00000497905.1
ENST00000463306.1
DZIP3

DAZ interacting zinc finger protein 3

chr12_+_4918342 0.015 ENST00000280684.3
ENST00000433855.1
KCNA6

potassium voltage-gated channel, shaker-related subfamily, member 6

chr14_+_22963806 0.015 ENST00000390493.1
TRAJ44
T cell receptor alpha joining 44
chr5_+_74062806 0.014 ENST00000296802.5
NSA2
NSA2 ribosome biogenesis homolog (S. cerevisiae)
chr7_+_129906660 0.013 ENST00000222481.4
CPA2
carboxypeptidase A2 (pancreatic)
chrX_-_49041242 0.012 ENST00000453382.1
ENST00000540849.1
ENST00000536904.1
ENST00000432913.1
PRICKLE3



prickle homolog 3 (Drosophila)



chr12_+_123717458 0.012 ENST00000253233.1
C12orf65
chromosome 12 open reading frame 65
chr16_+_69458537 0.011 ENST00000515314.1
ENST00000561792.1
ENST00000568237.1
CYB5B


cytochrome b5 type B (outer mitochondrial membrane)


chrX_+_86772787 0.009 ENST00000373114.4
KLHL4
kelch-like family member 4
chr14_+_81421355 0.009 ENST00000541158.2
TSHR
thyroid stimulating hormone receptor
chr1_-_149982624 0.009 ENST00000417191.1
ENST00000369135.4
OTUD7B

OTU domain containing 7B

chr14_+_81421861 0.007 ENST00000298171.2
TSHR
thyroid stimulating hormone receptor
chr2_+_48541776 0.006 ENST00000413569.1
ENST00000340553.3
FOXN2

forkhead box N2

chr1_-_23520755 0.006 ENST00000314113.3
HTR1D
5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
chr17_-_15244894 0.003 ENST00000338696.2
ENST00000543896.1
ENST00000539245.1
ENST00000539316.1
ENST00000395930.1
TEKT3




tektin 3




chr12_-_123717643 0.002 ENST00000541437.1
ENST00000606320.1
MPHOSPH9

M-phase phosphoprotein 9

chrY_+_16634483 0.002 ENST00000382872.1
NLGN4Y
neuroligin 4, Y-linked
chr14_+_81421921 0.001 ENST00000554263.1
ENST00000554435.1
TSHR

thyroid stimulating hormone receptor

chr7_+_130020180 0.000 ENST00000481342.1
ENST00000011292.3
ENST00000604896.1
CPA1


carboxypeptidase A1 (pancreatic)


chr5_-_74062930 0.000 ENST00000509430.1
ENST00000345239.2
ENST00000427854.2
ENST00000506778.1
GFM2



G elongation factor, mitochondrial 2




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.1 1.2 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.1 0.4 GO:0006663 platelet activating factor biosynthetic process(GO:0006663) positive regulation of vesicle fusion(GO:0031340) regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.1 0.5 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.1 0.3 GO:0002331 immature B cell differentiation(GO:0002327) pre-B cell differentiation(GO:0002329) pre-B cell allelic exclusion(GO:0002331)
0.1 0.2 GO:0006655 phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.1 0.5 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 0.4 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.4 GO:0046831 regulation of RNA export from nucleus(GO:0046831)
0.0 0.2 GO:0090224 regulation of spindle organization(GO:0090224)
0.0 0.1 GO:0048670 regulation of collateral sprouting(GO:0048670)
0.0 0.3 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.5 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.1 GO:0021896 forebrain astrocyte differentiation(GO:0021896) forebrain astrocyte development(GO:0021897)
0.0 0.5 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.1 GO:0060454 positive regulation of gastric acid secretion(GO:0060454) regulation of establishment of blood-brain barrier(GO:0090210) negative regulation of establishment of blood-brain barrier(GO:0090212)
0.0 0.2 GO:0031639 plasminogen activation(GO:0031639)
0.0 0.1 GO:0006857 oligopeptide transport(GO:0006857)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.4 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.2 GO:1900087 traversing start control point of mitotic cell cycle(GO:0007089) positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) positive regulation of cell cycle G1/S phase transition(GO:1902808)
0.0 0.1 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.0 0.1 GO:0048627 myoblast development(GO:0048627)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0 0.1 GO:0007498 mesoderm development(GO:0007498)
0.0 0.8 GO:0042632 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.0 0.3 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891) retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.1 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.1 GO:0009450 gamma-aminobutyric acid catabolic process(GO:0009450)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0000802 transverse filament(GO:0000802)
0.1 0.2 GO:0000806 Y chromosome(GO:0000806)
0.0 1.0 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.4 GO:0042588 zymogen granule(GO:0042588)
0.0 0.1 GO:0042629 mast cell granule(GO:0042629)
0.0 0.2 GO:0070652 HAUS complex(GO:0070652)
0.0 0.8 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.1 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.0 0.2 GO:0042555 MCM complex(GO:0042555)
0.0 0.3 GO:0031201 SNARE complex(GO:0031201)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0042289 MHC class II protein binding(GO:0042289)
0.2 0.5 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.1 0.3 GO:0004476 mannose-6-phosphate isomerase activity(GO:0004476)
0.1 0.3 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.1 0.4 GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.1 0.2 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.1 0.2 GO:0032183 SUMO binding(GO:0032183)
0.0 0.4 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.1 GO:0042910 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0 0.5 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.5 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.2 GO:0004457 lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
0.0 0.1 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.2 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.1 GO:0032145 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.0 0.1 GO:0015185 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.0 0.1 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.2 GO:0016409 palmitoyltransferase activity(GO:0016409)
0.0 0.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.3 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.2 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.1 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.2 GO:0004623 phospholipase A2 activity(GO:0004623)