Motif ID: NKX3-1

Z-value: 1.807


Transcription factors associated with NKX3-1:

Gene SymbolEntrez IDGene Name
NKX3-1 ENSG00000167034.9 NKX3-1



Activity profile for motif NKX3-1.

activity profile for motif NKX3-1


Sorted Z-values histogram for motif NKX3-1

Sorted Z-values for motif NKX3-1



Network of associatons between targets according to the STRING database.



First level regulatory network of NKX3-1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_-_14180778 3.803 ENST00000380924.1
ENST00000543693.1
NFIB

nuclear factor I/B

chr18_+_61445007 3.733 ENST00000447428.1
ENST00000546027.1
SERPINB7

serpin peptidase inhibitor, clade B (ovalbumin), member 7

chr20_-_56285595 3.601 ENST00000395816.3
ENST00000347215.4
PMEPA1

prostate transmembrane protein, androgen induced 1

chr9_+_706842 3.380 ENST00000382293.3
KANK1
KN motif and ankyrin repeat domains 1
chr20_-_56286479 3.262 ENST00000265626.4
PMEPA1
prostate transmembrane protein, androgen induced 1
chr8_-_49834299 3.256 ENST00000396822.1
SNAI2
snail family zinc finger 2
chr16_+_3068393 3.074 ENST00000573001.1
TNFRSF12A
tumor necrosis factor receptor superfamily, member 12A
chr8_-_49833978 3.065 ENST00000020945.1
SNAI2
snail family zinc finger 2
chr8_+_30300119 2.694 ENST00000520191.1
RBPMS
RNA binding protein with multiple splicing
chr17_+_48609903 2.619 ENST00000268933.3
EPN3
epsin 3
chr3_+_158991025 2.416 ENST00000337808.6
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr7_+_79765071 2.386 ENST00000457358.2
GNAI1
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chr7_+_121513143 2.108 ENST00000393386.2
PTPRZ1
protein tyrosine phosphatase, receptor-type, Z polypeptide 1
chr1_+_186798073 2.063 ENST00000367466.3
ENST00000442353.2
PLA2G4A

phospholipase A2, group IVA (cytosolic, calcium-dependent)

chrX_-_107681633 1.892 ENST00000394872.2
ENST00000334504.7
COL4A6

collagen, type IV, alpha 6

chr11_+_101983176 1.882 ENST00000524575.1
YAP1
Yes-associated protein 1
chr11_+_114168085 1.826 ENST00000541754.1
NNMT
nicotinamide N-methyltransferase
chrX_+_114795489 1.740 ENST00000355899.3
ENST00000537301.1
ENST00000289290.3
PLS3


plastin 3


chr9_+_90341024 1.679 ENST00000340342.6
ENST00000342020.5
CTSL

cathepsin L

chr19_-_44174330 1.638 ENST00000340093.3
PLAUR
plasminogen activator, urokinase receptor
chr4_-_90757364 1.631 ENST00000508895.1
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr2_+_102456277 1.565 ENST00000421882.1
MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr1_-_32169920 1.559 ENST00000373672.3
ENST00000373668.3
COL16A1

collagen, type XVI, alpha 1

chrX_-_153637612 1.556 ENST00000369807.1
ENST00000369808.3
DNASE1L1

deoxyribonuclease I-like 1

chr1_-_32169761 1.537 ENST00000271069.6
COL16A1
collagen, type XVI, alpha 1
chr5_+_125758865 1.243 ENST00000542322.1
ENST00000544396.1
GRAMD3

GRAM domain containing 3

chr5_+_125758813 1.209 ENST00000285689.3
ENST00000515200.1
GRAMD3

GRAM domain containing 3

chr1_-_208417620 1.173 ENST00000367033.3
PLXNA2
plexin A2
chr4_-_90756769 1.153 ENST00000345009.4
ENST00000505199.1
ENST00000502987.1
SNCA


synuclein, alpha (non A4 component of amyloid precursor)


chr17_-_7307358 1.093 ENST00000535512.1
ENST00000576017.1
ENST00000302422.3
TMEM256-PLSCR3
TMEM256

TMEM256-PLSCR3 readthrough (NMD candidate)
transmembrane protein 256

chr5_+_96211643 1.031 ENST00000437043.3
ENST00000510373.1
ERAP2

endoplasmic reticulum aminopeptidase 2

chr17_+_48610074 1.028 ENST00000503690.1
ENST00000514874.1
ENST00000537145.1
ENST00000541226.1
EPN3



epsin 3



chr3_-_48632593 0.974 ENST00000454817.1
ENST00000328333.8
COL7A1

collagen, type VII, alpha 1

chr4_-_170924888 0.961 ENST00000502832.1
ENST00000393704.3
MFAP3L

microfibrillar-associated protein 3-like

chr17_+_2699697 0.946 ENST00000254695.8
ENST00000366401.4
ENST00000542807.1
RAP1GAP2


RAP1 GTPase activating protein 2


chr19_-_44174305 0.938 ENST00000601723.1
ENST00000339082.3
PLAUR

plasminogen activator, urokinase receptor

chr5_+_96038476 0.868 ENST00000511049.1
ENST00000309190.5
ENST00000510156.1
ENST00000509903.1
ENST00000511782.1
ENST00000504465.1
CAST





calpastatin





chr3_-_18480260 0.849 ENST00000454909.2
SATB1
SATB homeobox 1
chrX_-_114253536 0.838 ENST00000371936.1
IL13RA2
interleukin 13 receptor, alpha 2
chr4_-_141677267 0.819 ENST00000442267.2
TBC1D9
TBC1 domain family, member 9 (with GRAM domain)
chr9_+_116263639 0.791 ENST00000343817.5
RGS3
regulator of G-protein signaling 3
chr1_-_6445809 0.699 ENST00000377855.2
ACOT7
acyl-CoA thioesterase 7
chr3_+_100428188 0.696 ENST00000418917.2
ENST00000490574.1
TFG

TRK-fused gene

chr4_+_56719782 0.692 ENST00000381295.2
ENST00000346134.7
ENST00000349598.6
EXOC1


exocyst complex component 1


chr1_-_153066998 0.680 ENST00000368750.3
SPRR2E
small proline-rich protein 2E
chr1_-_153113927 0.663 ENST00000368752.4
SPRR2B
small proline-rich protein 2B
chr16_-_69760409 0.633 ENST00000561500.1
ENST00000439109.2
ENST00000564043.1
ENST00000379046.2
ENST00000379047.3
NQO1




NAD(P)H dehydrogenase, quinone 1




chr6_+_143999072 0.605 ENST00000440869.2
ENST00000367582.3
ENST00000451827.2
PHACTR2


phosphatase and actin regulator 2


chr3_+_100428316 0.584 ENST00000479672.1
ENST00000476228.1
ENST00000463568.1
TFG


TRK-fused gene


chr12_+_110011571 0.569 ENST00000539696.1
ENST00000228510.3
ENST00000392727.3
MVK


mevalonate kinase


chr3_+_100428268 0.568 ENST00000240851.4
TFG
TRK-fused gene
chr17_-_76870126 0.557 ENST00000586057.1
TIMP2
TIMP metallopeptidase inhibitor 2
chr6_-_159240415 0.557 ENST00000367075.3
EZR
ezrin
chr5_-_176889381 0.543 ENST00000393563.4
ENST00000512501.1
DBN1

drebrin 1

chr17_-_76870222 0.530 ENST00000585421.1
TIMP2
TIMP metallopeptidase inhibitor 2
chr13_+_115000556 0.530 ENST00000252458.6
CDC16
cell division cycle 16
chr3_+_52489503 0.527 ENST00000345716.4
NISCH
nischarin
chr8_-_38034192 0.517 ENST00000520755.1
LSM1
LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr6_+_63921399 0.495 ENST00000356170.3
FKBP1C
FK506 binding protein 1C
chr1_-_21377447 0.482 ENST00000374937.3
ENST00000264211.8
EIF4G3

eukaryotic translation initiation factor 4 gamma, 3

chr1_-_60392452 0.480 ENST00000371204.3
CYP2J2
cytochrome P450, family 2, subfamily J, polypeptide 2
chr12_-_53298841 0.470 ENST00000293308.6
KRT8
keratin 8
chr7_-_2883928 0.457 ENST00000275364.3
GNA12
guanine nucleotide binding protein (G protein) alpha 12
chr10_-_32345305 0.440 ENST00000302418.4
KIF5B
kinesin family member 5B
chr4_-_70626314 0.427 ENST00000510821.1
SULT1B1
sulfotransferase family, cytosolic, 1B, member 1
chr7_+_5938351 0.426 ENST00000325974.6
CCZ1
CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
chr1_-_153085984 0.421 ENST00000468739.1
SPRR2F
small proline-rich protein 2F
chr14_-_23388338 0.420 ENST00000555209.1
ENST00000554256.1
ENST00000557403.1
ENST00000557549.1
ENST00000555676.1
ENST00000557571.1
ENST00000557464.1
ENST00000554618.1
ENST00000556862.1
ENST00000555722.1
ENST00000346528.5
ENST00000542016.2
ENST00000399922.2
ENST00000557227.1
ENST00000359890.3
RBM23














RNA binding motif protein 23














chr8_-_38034234 0.419 ENST00000311351.4
LSM1
LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr13_+_50570019 0.415 ENST00000442421.1
TRIM13
tripartite motif containing 13
chr11_-_64684672 0.402 ENST00000377264.3
ENST00000421419.2
ATG2A

autophagy related 2A

chr19_+_17970677 0.396 ENST00000222247.5
RPL18A
ribosomal protein L18a
chr19_+_17970693 0.394 ENST00000600147.1
ENST00000599898.1
RPL18A

ribosomal protein L18a

chr17_+_42422662 0.375 ENST00000593167.1
ENST00000585512.1
ENST00000591740.1
ENST00000592783.1
ENST00000587387.1
ENST00000588237.1
ENST00000589265.1
GRN






granulin






chrX_-_153236819 0.370 ENST00000354233.3
HCFC1
host cell factor C1 (VP16-accessory protein)
chr17_-_37009882 0.363 ENST00000378096.3
ENST00000394332.1
ENST00000394333.1
ENST00000577407.1
ENST00000479035.2
RPL23




ribosomal protein L23




chr5_+_150404904 0.357 ENST00000521632.1
GPX3
glutathione peroxidase 3 (plasma)
chr12_-_89920030 0.353 ENST00000413530.1
ENST00000547474.1
GALNT4
POC1B-GALNT4
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)
POC1B-GALNT4 readthrough
chr15_+_44084503 0.351 ENST00000409960.2
ENST00000409646.1
ENST00000594896.1
ENST00000339624.5
ENST00000409291.1
ENST00000402131.1
ENST00000403425.1
ENST00000430901.1
SERF2







small EDRK-rich factor 2







chr6_-_144385698 0.350 ENST00000444202.1
ENST00000437412.1
PLAGL1

pleiomorphic adenoma gene-like 1

chr6_-_33285505 0.342 ENST00000431845.2
ZBTB22
zinc finger and BTB domain containing 22
chr5_-_43412418 0.339 ENST00000537013.1
ENST00000361115.4
CCL28

chemokine (C-C motif) ligand 28

chr14_-_65409438 0.339 ENST00000557049.1
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr5_+_140723601 0.336 ENST00000253812.6
PCDHGA3
protocadherin gamma subfamily A, 3
chr11_+_71791693 0.334 ENST00000289488.2
ENST00000447974.1
LRTOMT

leucine rich transmembrane and O-methyltransferase domain containing

chr7_+_5938386 0.334 ENST00000537980.1
CCZ1
CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
chr12_-_89919965 0.331 ENST00000548729.1
POC1B-GALNT4
POC1B-GALNT4 readthrough
chr17_+_66521936 0.330 ENST00000592800.1
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr1_-_48866517 0.329 ENST00000371841.1
SPATA6
spermatogenesis associated 6
chr2_+_64069459 0.329 ENST00000445915.2
ENST00000475462.1
UGP2

UDP-glucose pyrophosphorylase 2

chr2_+_64068844 0.328 ENST00000337130.5
UGP2
UDP-glucose pyrophosphorylase 2
chr2_+_173686303 0.322 ENST00000397087.3
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr3_+_98482175 0.320 ENST00000485391.1
ENST00000492254.1
ST3GAL6

ST3 beta-galactoside alpha-2,3-sialyltransferase 6

chr16_-_3074231 0.314 ENST00000572355.1
ENST00000248089.3
ENST00000574980.1
ENST00000354679.3
ENST00000396916.1
ENST00000573842.1
HCFC1R1





host cell factor C1 regulator 1 (XPO1 dependent)





chr6_-_57087042 0.306 ENST00000317483.3
RAB23
RAB23, member RAS oncogene family
chr7_+_77325738 0.304 ENST00000334955.8
RSBN1L
round spermatid basic protein 1-like
chr12_-_125398654 0.300 ENST00000541645.1
ENST00000540351.1
UBC

ubiquitin C

chr11_+_65337901 0.297 ENST00000309328.3
ENST00000531405.1
ENST00000527920.1
ENST00000526877.1
ENST00000533115.1
ENST00000526433.1
SSSCA1





Sjogren syndrome/scleroderma autoantigen 1





chr12_+_111051902 0.297 ENST00000397655.3
ENST00000471804.2
ENST00000377654.3
ENST00000397659.4
TCTN1



tectonic family member 1



chr17_-_29624343 0.295 ENST00000247271.4
OMG
oligodendrocyte myelin glycoprotein
chr11_+_67798090 0.291 ENST00000313468.5
NDUFS8
NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
chrX_-_153237258 0.284 ENST00000310441.7
HCFC1
host cell factor C1 (VP16-accessory protein)
chr7_-_6865826 0.279 ENST00000538180.1
CCZ1B
CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
chr17_+_42422637 0.278 ENST00000053867.3
ENST00000588143.1
GRN

granulin

chr15_+_85147127 0.273 ENST00000541040.1
ENST00000538076.1
ENST00000485222.2
ZSCAN2


zinc finger and SCAN domain containing 2


chr17_-_64187973 0.270 ENST00000583358.1
ENST00000392769.2
CEP112

centrosomal protein 112kDa

chr19_-_15544099 0.269 ENST00000599910.2
WIZ
widely interspaced zinc finger motifs
chr4_-_122791583 0.266 ENST00000506636.1
ENST00000264499.4
BBS7

Bardet-Biedl syndrome 7

chr12_-_10562356 0.264 ENST00000309384.1
KLRC4
killer cell lectin-like receptor subfamily C, member 4
chr1_+_158223923 0.261 ENST00000289429.5
CD1A
CD1a molecule
chrX_+_153237740 0.258 ENST00000369982.4
TMEM187
transmembrane protein 187
chr16_-_66864806 0.258 ENST00000566336.1
ENST00000394074.2
ENST00000563185.2
ENST00000359087.4
ENST00000379463.2
ENST00000565535.1
ENST00000290810.3
NAE1






NEDD8 activating enzyme E1 subunit 1






chr11_+_8704748 0.244 ENST00000526562.1
ENST00000525981.1
RPL27A

ribosomal protein L27a

chr16_+_1832902 0.244 ENST00000262302.9
ENST00000563136.1
ENST00000565987.1
ENST00000543305.1
ENST00000568287.1
ENST00000565134.1
NUBP2





nucleotide binding protein 2





chr1_+_22962948 0.237 ENST00000374642.3
C1QA
complement component 1, q subcomponent, A chain
chr9_+_36572851 0.234 ENST00000298048.2
ENST00000538311.1
ENST00000536987.1
ENST00000545008.1
ENST00000536860.1
ENST00000536329.1
ENST00000541717.1
ENST00000543751.1
MELK







maternal embryonic leucine zipper kinase







chr4_-_10118469 0.231 ENST00000499869.2
WDR1
WD repeat domain 1
chr16_+_22501658 0.229 ENST00000415833.2
NPIPB5
nuclear pore complex interacting protein family, member B5
chr11_+_67798114 0.227 ENST00000453471.2
ENST00000528492.1
ENST00000526339.1
ENST00000525419.1
NDUFS8



NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)



chr20_+_123010 0.223 ENST00000382398.3
DEFB126
defensin, beta 126
chr20_+_2821340 0.217 ENST00000380445.3
ENST00000380469.3
VPS16

vacuolar protein sorting 16 homolog (S. cerevisiae)

chr15_+_44084040 0.206 ENST00000249786.4
SERF2
small EDRK-rich factor 2
chr10_-_104953009 0.198 ENST00000470299.1
ENST00000343289.5
NT5C2

5'-nucleotidase, cytosolic II

chr12_+_111051832 0.196 ENST00000550703.2
ENST00000551590.1
TCTN1

tectonic family member 1

chr17_-_7145475 0.193 ENST00000571129.1
ENST00000571253.1
ENST00000573928.1
GABARAP


GABA(A) receptor-associated protein


chr12_-_125398602 0.192 ENST00000541272.1
ENST00000535131.1
UBC

ubiquitin C

chr2_+_113672770 0.190 ENST00000311328.2
IL37
interleukin 37
chr1_+_158323244 0.189 ENST00000434258.1
CD1E
CD1e molecule
chr7_+_7222233 0.187 ENST00000436587.2
C1GALT1
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
chr6_+_43266063 0.183 ENST00000372574.3
SLC22A7
solute carrier family 22 (organic anion transporter), member 7
chr8_-_93029865 0.183 ENST00000422361.2
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr17_-_2966901 0.183 ENST00000575751.1
OR1D5
olfactory receptor, family 1, subfamily D, member 5
chr13_+_115000521 0.181 ENST00000252457.5
ENST00000375308.1
CDC16

cell division cycle 16

chr1_-_77685084 0.180 ENST00000370812.3
ENST00000359130.1
ENST00000445065.1
ENST00000370813.5
PIGK



phosphatidylinositol glycan anchor biosynthesis, class K



chr19_-_1592652 0.175 ENST00000156825.1
ENST00000434436.3
MBD3

methyl-CpG binding domain protein 3

chr1_-_216978709 0.175 ENST00000360012.3
ESRRG
estrogen-related receptor gamma
chr1_+_173793777 0.172 ENST00000239457.5
DARS2
aspartyl-tRNA synthetase 2, mitochondrial
chr2_-_79313973 0.169 ENST00000454188.1
REG1B
regenerating islet-derived 1 beta
chrX_-_24665353 0.159 ENST00000379144.2
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr17_+_80674559 0.151 ENST00000269373.6
ENST00000535965.1
ENST00000577128.1
ENST00000573158.1
FN3KRP



fructosamine 3 kinase related protein



chr14_-_74551172 0.147 ENST00000553458.1
ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr10_+_135204338 0.144 ENST00000468317.2
RP11-108K14.8
Mitochondrial GTPase 1
chr20_-_34330129 0.143 ENST00000397370.3
ENST00000528062.3
ENST00000407261.4
ENST00000374038.3
ENST00000361162.6
RBM39




RNA binding motif protein 39




chr7_+_110731062 0.140 ENST00000308478.5
ENST00000451085.1
ENST00000422987.3
ENST00000421101.1
LRRN3



leucine rich repeat neuronal 3



chr21_-_46964306 0.139 ENST00000443742.1
ENST00000528477.1
ENST00000567670.1
SLC19A1


solute carrier family 19 (folate transporter), member 1


chr16_+_56969284 0.139 ENST00000568358.1
HERPUD1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr4_+_88529681 0.139 ENST00000399271.1
DSPP
dentin sialophosphoprotein
chr3_+_132316081 0.139 ENST00000249887.2
ACKR4
atypical chemokine receptor 4
chr1_+_171217622 0.138 ENST00000433267.1
ENST00000367750.3
FMO1

flavin containing monooxygenase 1

chrX_+_13671225 0.130 ENST00000545566.1
ENST00000544987.1
ENST00000314720.4
TCEANC


transcription elongation factor A (SII) N-terminal and central domain containing


chr7_-_138794394 0.129 ENST00000242351.5
ENST00000471652.1
ZC3HAV1

zinc finger CCCH-type, antiviral 1

chr11_+_67798363 0.126 ENST00000525628.1
NDUFS8
NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
chr9_-_104145795 0.117 ENST00000259407.2
BAAT
bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)
chr2_-_187367356 0.116 ENST00000595956.1
AC018867.2
AC018867.2
chr1_-_160232197 0.110 ENST00000419626.1
ENST00000610139.1
ENST00000475733.1
ENST00000407642.2
ENST00000368073.3
ENST00000326837.2
DCAF8





DDB1 and CUL4 associated factor 8





chr11_+_7506713 0.106 ENST00000329293.3
ENST00000534244.1
OLFML1

olfactomedin-like 1

chr11_+_9482551 0.102 ENST00000438144.2
ENST00000526657.1
ENST00000299606.2
ENST00000534265.1
ENST00000412390.2
ZNF143




zinc finger protein 143




chr7_-_112430647 0.096 ENST00000312814.6
TMEM168
transmembrane protein 168
chr10_-_28571015 0.094 ENST00000375719.3
ENST00000375732.1
MPP7

membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)

chr1_-_160232291 0.092 ENST00000368074.1
ENST00000447377.1
DCAF8

DDB1 and CUL4 associated factor 8

chr19_-_14889349 0.092 ENST00000315576.3
ENST00000392967.2
ENST00000346057.1
ENST00000353876.1
ENST00000353005.1
EMR2




egf-like module containing, mucin-like, hormone receptor-like 2




chr1_+_151372010 0.091 ENST00000290541.6
PSMB4
proteasome (prosome, macropain) subunit, beta type, 4
chr7_+_141463897 0.091 ENST00000247879.2
TAS2R3
taste receptor, type 2, member 3
chr1_+_158323486 0.090 ENST00000444681.2
ENST00000368167.3
CD1E

CD1e molecule

chr12_+_4829507 0.089 ENST00000252318.2
GALNT8
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 8 (GalNAc-T8)
chr12_+_81110684 0.083 ENST00000228644.3
MYF5
myogenic factor 5
chr14_-_65409502 0.082 ENST00000389614.5
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr2_+_216974020 0.078 ENST00000392132.2
ENST00000417391.1
XRCC5

X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)

chr16_-_21436459 0.074 ENST00000448012.2
ENST00000504841.2
ENST00000419180.2
NPIPB3


nuclear pore complex interacting protein family, member B3


chr19_-_55791563 0.073 ENST00000588971.1
ENST00000255631.5
ENST00000587551.1
HSPBP1


HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1


chr16_-_69373396 0.065 ENST00000562595.1
ENST00000562081.1
ENST00000306875.4
COG8


component of oligomeric golgi complex 8


chr13_+_27998681 0.063 ENST00000381140.4
GTF3A
general transcription factor IIIA
chrX_-_38186775 0.062 ENST00000339363.3
ENST00000309513.3
ENST00000338898.3
ENST00000342811.3
ENST00000378505.2
RPGR




retinitis pigmentosa GTPase regulator




chr6_+_52930237 0.060 ENST00000323557.7
FBXO9
F-box protein 9
chr15_-_31393910 0.058 ENST00000397795.2
ENST00000256552.6
ENST00000559179.1
TRPM1


transient receptor potential cation channel, subfamily M, member 1


chr12_-_4553385 0.055 ENST00000543077.1
FGF6
fibroblast growth factor 6
chr8_-_97247759 0.053 ENST00000518406.1
ENST00000523920.1
ENST00000287022.5
UQCRB


ubiquinol-cytochrome c reductase binding protein


chr16_+_69373323 0.050 ENST00000254940.5
NIP7
NIP7, nucleolar pre-rRNA processing protein
chr5_+_64920826 0.048 ENST00000438419.2
ENST00000231526.4
ENST00000505553.1
ENST00000545191.1
TRAPPC13



trafficking protein particle complex 13



chr22_-_50523760 0.042 ENST00000395876.2
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr12_-_57039739 0.040 ENST00000552959.1
ENST00000551020.1
ENST00000553007.2
ENST00000552919.1
ENST00000552104.1
ENST00000262030.3
ATP5B





ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide





chr17_-_34257731 0.038 ENST00000431884.2
ENST00000425909.3
ENST00000394528.3
ENST00000430160.2
RDM1



RAD52 motif 1



chr12_-_54978086 0.037 ENST00000553113.1
PPP1R1A
protein phosphatase 1, regulatory (inhibitor) subunit 1A
chr7_+_100303676 0.034 ENST00000303151.4
POP7
processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae)
chr12_+_12966250 0.034 ENST00000352940.4
ENST00000358007.3
ENST00000544400.1
DDX47


DEAD (Asp-Glu-Ala-Asp) box polypeptide 47


chr12_-_125398850 0.033 ENST00000535859.1
ENST00000546271.1
ENST00000540700.1
ENST00000546120.1
UBC



ubiquitin C



chr12_+_113229452 0.032 ENST00000389385.4
RPH3A
rabphilin 3A homolog (mouse)
chr11_-_71823715 0.031 ENST00000545944.1
ENST00000502597.2
ANAPC15

anaphase promoting complex subunit 15

chr11_-_101454234 0.029 ENST00000348423.4
ENST00000360497.4
ENST00000532133.1
TRPC6


transient receptor potential cation channel, subfamily C, member 6


chr9_+_117350009 0.024 ENST00000374050.3
ATP6V1G1
ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1
chr11_-_71823796 0.020 ENST00000545680.1
ENST00000543587.1
ENST00000538393.1
ENST00000535234.1
ENST00000227618.4
ENST00000535503.1
ANAPC15





anaphase promoting complex subunit 15





chr1_+_171217677 0.019 ENST00000402921.2
FMO1
flavin containing monooxygenase 1
chr1_-_35497506 0.018 ENST00000317538.5
ENST00000373340.2
ENST00000357182.4
ZMYM6


zinc finger, MYM-type 6


chr4_+_159131630 0.018 ENST00000504569.1
ENST00000509278.1
ENST00000514558.1
ENST00000503200.1
TMEM144



transmembrane protein 144



chr11_+_8040739 0.015 ENST00000534099.1
TUB
tubby bipartite transcription factor
chr6_+_42928485 0.014 ENST00000372808.3
GNMT
glycine N-methyltransferase
chr1_+_173793641 0.013 ENST00000361951.4
DARS2
aspartyl-tRNA synthetase 2, mitochondrial
chr17_+_7358889 0.009 ENST00000575379.1
CHRNB1
cholinergic receptor, nicotinic, beta 1 (muscle)
chr6_-_31648150 0.008 ENST00000375858.3
ENST00000383237.4
LY6G5C

lymphocyte antigen 6 complex, locus G5C

chrX_-_102757802 0.006 ENST00000372633.1
RAB40A
RAB40A, member RAS oncogene family

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 6.3 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.6 2.8 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.5 2.1 GO:0006663 platelet activating factor biosynthetic process(GO:0006663) positive regulation of vesicle fusion(GO:0031340) regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.5 3.1 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.4 2.8 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.3 1.9 GO:0060242 contact inhibition(GO:0060242)
0.2 1.2 GO:0021535 cell migration in hindbrain(GO:0021535)
0.2 0.7 GO:0019046 release from viral latency(GO:0019046)
0.1 0.3 GO:0048670 regulation of collateral sprouting(GO:0048670)
0.1 0.4 GO:0007028 cytoplasm organization(GO:0007028) ribonucleoprotein complex disassembly(GO:0032988)
0.1 2.1 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.1 0.4 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.1 0.7 GO:0006011 UDP-glucose metabolic process(GO:0006011) UDP-glucuronate biosynthetic process(GO:0006065)
0.1 0.4 GO:0009609 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
0.1 1.0 GO:0019885 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1 0.6 GO:0022614 membrane to membrane docking(GO:0022614)
0.1 6.7 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.1 3.4 GO:0030837 negative regulation of actin filament polymerization(GO:0030837)
0.1 0.3 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.1 1.7 GO:0031424 keratinization(GO:0031424)
0.1 0.4 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.9 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.6 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 2.4 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0 0.2 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.3 GO:0019614 phenol-containing compound catabolic process(GO:0019336) catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.0 0.3 GO:0044818 mitotic G2/M transition checkpoint(GO:0044818) protein neddylation(GO:0045116)
0.0 0.3 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.1 GO:0051958 methotrexate transport(GO:0051958)
0.0 0.2 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 1.6 GO:0006308 DNA catabolic process(GO:0006308)
0.0 0.5 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.2 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.0 0.5 GO:0007128 meiotic prophase I(GO:0007128)
0.0 0.5 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.0 0.6 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.0 2.3 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.4 GO:0042403 thyroid hormone metabolic process(GO:0042403)
0.0 0.1 GO:1902414 protein localization to adherens junction(GO:0071896) protein localization to cell junction(GO:1902414)
0.0 0.7 GO:0006887 exocytosis(GO:0006887)
0.0 0.3 GO:0006968 cellular defense response(GO:0006968)
0.0 0.3 GO:0021513 spinal cord dorsal/ventral patterning(GO:0021513)
0.0 0.8 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.5 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.0 0.4 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 2.2 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.7 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.3 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 0.5 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.0 0.3 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 0.1 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.1 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 1.1 GO:0030814 regulation of cAMP metabolic process(GO:0030814)
0.0 0.1 GO:0042693 muscle cell fate commitment(GO:0042693)
0.0 0.1 GO:0071478 cellular response to radiation(GO:0071478)
0.0 0.1 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.5 GO:0032480 negative regulation of type I interferon production(GO:0032480)
0.0 0.8 GO:0006921 cellular component disassembly involved in execution phase of apoptosis(GO:0006921) execution phase of apoptosis(GO:0097194)
0.0 2.1 GO:0006470 protein dephosphorylation(GO:0006470)
0.0 0.3 GO:0008299 isoprenoid biosynthetic process(GO:0008299)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.1 GO:0005593 FACIT collagen trimer(GO:0005593)
0.2 1.9 GO:0005587 collagen type IV trimer(GO:0005587)
0.1 2.8 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 2.1 GO:0042588 zymogen granule(GO:0042588)
0.1 0.7 GO:0000145 exocyst(GO:0000145)
0.1 1.8 GO:0001533 cornified envelope(GO:0001533)
0.1 0.2 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 0.7 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 2.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.2 GO:0005602 complement component C1 complex(GO:0005602)
0.0 0.6 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 1.0 GO:0098644 complex of collagen trimers(GO:0098644)
0.0 3.6 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 0.3 GO:0060170 BBSome(GO:0034464) ciliary membrane(GO:0060170)
0.0 0.4 GO:0035253 ciliary rootlet(GO:0035253)
0.0 3.5 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.3 GO:0043202 lysosomal lumen(GO:0043202)
0.0 3.1 GO:0001726 ruffle(GO:0001726)
0.0 0.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.7 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.7 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.2 GO:0030897 HOPS complex(GO:0030897)
0.0 0.2 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.9 GO:0005625 obsolete soluble fraction(GO:0005625)
0.0 1.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 1.3 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.1 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.3 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.5 GO:0055037 recycling endosome(GO:0055037)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.6 2.8 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.5 1.8 GO:0008112 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.4 2.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.4 2.4 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.2 0.7 GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.2 6.8 GO:0050699 WW domain binding(GO:0050699)
0.2 2.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 0.9 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1 2.7 GO:0008143 poly(A) binding(GO:0008143)
0.1 1.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 1.6 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.1 0.8 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.1 1.9 GO:0070064 proline-rich region binding(GO:0070064)
0.1 1.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.2 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.6 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.3 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 0.8 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.5 GO:0050780 dopamine receptor binding(GO:0050780)
0.0 3.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0015350 methotrexate transporter activity(GO:0015350)
0.0 0.5 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.5 GO:0005522 profilin binding(GO:0005522)
0.0 3.6 GO:0005178 integrin binding(GO:0005178)
0.0 0.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.2 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.4 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.9 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.5 GO:0070330 aromatase activity(GO:0070330)
0.0 0.7 GO:0030552 cAMP binding(GO:0030552)
0.0 0.3 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 0.2 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.2 GO:0050811 GABA receptor binding(GO:0050811)
0.0 1.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.6 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.2 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.2 GO:0015301 anion:anion antiporter activity(GO:0015301)
0.0 0.3 GO:0008373 sialyltransferase activity(GO:0008373)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 ST_IL_13_PATHWAY Interleukin 13 (IL-13) Pathway
0.1 2.4 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.