Motif ID: NKX3-2

Z-value: 1.662


Transcription factors associated with NKX3-2:

Gene SymbolEntrez IDGene Name
NKX3-2 ENSG00000109705.7 NKX3-2



Activity profile for motif NKX3-2.

activity profile for motif NKX3-2


Sorted Z-values histogram for motif NKX3-2

Sorted Z-values for motif NKX3-2



Network of associatons between targets according to the STRING database.



First level regulatory network of NKX3-2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_-_98031310 5.472 ENST00000427367.2
ENST00000413476.2
BLNK

B-cell linker

chr10_-_98031265 4.340 ENST00000224337.5
ENST00000371176.2
BLNK

B-cell linker

chr5_-_149792295 2.338 ENST00000518797.1
ENST00000524315.1
ENST00000009530.7
ENST00000377795.3
CD74



CD74 molecule, major histocompatibility complex, class II invariant chain



chr11_+_60223225 1.878 ENST00000524807.1
ENST00000345732.4
MS4A1

membrane-spanning 4-domains, subfamily A, member 1

chr14_-_106406090 1.786 ENST00000390593.2
IGHV6-1
immunoglobulin heavy variable 6-1
chr14_-_106963409 1.770 ENST00000390621.2
IGHV1-45
immunoglobulin heavy variable 1-45
chr6_-_32557610 1.724 ENST00000360004.5
HLA-DRB1
major histocompatibility complex, class II, DR beta 1
chr2_+_17721920 1.717 ENST00000295156.4
VSNL1
visinin-like 1
chr19_-_6720686 1.678 ENST00000245907.6
C3
complement component 3
chr11_+_60223312 1.637 ENST00000532491.1
ENST00000532073.1
ENST00000534668.1
ENST00000528313.1
ENST00000533306.1
MS4A1




membrane-spanning 4-domains, subfamily A, member 1




chrX_+_105937068 1.399 ENST00000324342.3
RNF128
ring finger protein 128, E3 ubiquitin protein ligase
chr6_+_29910301 1.393 ENST00000376809.5
ENST00000376802.2
HLA-A

major histocompatibility complex, class I, A

chr10_-_47173994 1.373 ENST00000414655.2
ENST00000545298.1
ENST00000359178.4
ENST00000358140.4
ENST00000503031.1
ANXA8L1



LINC00842
annexin A8-like 1



long intergenic non-protein coding RNA 842
chr8_+_86376081 1.352 ENST00000285379.5
CA2
carbonic anhydrase II
chr15_+_81475047 1.348 ENST00000559388.1
IL16
interleukin 16
chr6_+_32821924 1.344 ENST00000374859.2
ENST00000453265.2
PSMB9

proteasome (prosome, macropain) subunit, beta type, 9

chrX_-_107681633 1.323 ENST00000394872.2
ENST00000334504.7
COL4A6

collagen, type IV, alpha 6

chr6_-_32821599 1.257 ENST00000354258.4
TAP1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr10_+_47746929 1.238 ENST00000340243.6
ENST00000374277.5
ENST00000449464.2
ENST00000538825.1
ENST00000335083.5
ANXA8L2



AL603965.1
annexin A8-like 2



Protein LOC100996760
chr10_-_95360983 1.188 ENST00000371464.3
RBP4
retinol binding protein 4, plasma
chr14_+_23016437 1.180 ENST00000478163.3
TRAC
T cell receptor alpha constant
chr10_+_7745303 1.180 ENST00000429820.1
ENST00000379587.4
ITIH2

inter-alpha-trypsin inhibitor heavy chain 2

chr6_-_32784687 1.158 ENST00000447394.1
ENST00000438763.2
HLA-DOB

major histocompatibility complex, class II, DO beta

chr7_+_115862858 1.133 ENST00000393481.2
TES
testis derived transcript (3 LIM domains)
chr17_-_46507537 1.130 ENST00000336915.6
SKAP1
src kinase associated phosphoprotein 1
chr10_+_7745232 1.103 ENST00000358415.4
ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr11_-_119993979 1.093 ENST00000524816.3
ENST00000525327.1
TRIM29

tripartite motif containing 29

chr13_-_47012325 1.086 ENST00000409879.2
KIAA0226L
KIAA0226-like
chr21_-_43816052 1.042 ENST00000398405.1
TMPRSS3
transmembrane protease, serine 3
chr12_+_4382917 1.040 ENST00000261254.3
CCND2
cyclin D2
chr19_-_7764281 0.992 ENST00000360067.4
FCER2
Fc fragment of IgE, low affinity II, receptor for (CD23)
chr5_+_156696362 0.990 ENST00000377576.3
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr11_+_128563652 0.963 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr3_-_149688502 0.934 ENST00000481767.1
ENST00000475518.1
PFN2

profilin 2

chr17_-_39928106 0.891 ENST00000540235.1
JUP
junction plakoglobin
chr1_+_35247859 0.858 ENST00000373362.3
GJB3
gap junction protein, beta 3, 31kDa
chr6_-_32731299 0.827 ENST00000435145.2
ENST00000437316.2
HLA-DQB2

major histocompatibility complex, class II, DQ beta 2

chr2_-_70781087 0.811 ENST00000394241.3
ENST00000295400.6
TGFA

transforming growth factor, alpha

chrX_+_13707235 0.792 ENST00000464506.1
RAB9A
RAB9A, member RAS oncogene family
chr5_+_156712372 0.781 ENST00000541131.1
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr18_+_55816546 0.765 ENST00000435432.2
ENST00000357895.5
ENST00000586263.1
NEDD4L


neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase


chr17_+_18380051 0.759 ENST00000581545.1
ENST00000582333.1
ENST00000328114.6
ENST00000412421.2
ENST00000583322.1
ENST00000584941.1
LGALS9C





lectin, galactoside-binding, soluble, 9C





chr14_-_67859422 0.757 ENST00000556532.1
PLEK2
pleckstrin 2
chr1_+_60280458 0.721 ENST00000455990.1
ENST00000371208.3
HOOK1

hook microtubule-tethering protein 1

chr12_-_80084862 0.704 ENST00000328827.4
PAWR
PRKC, apoptosis, WT1, regulator
chr1_+_86889769 0.697 ENST00000370565.4
CLCA2
chloride channel accessory 2
chr12_+_53693466 0.694 ENST00000267103.5
ENST00000548632.1
C12orf10

chromosome 12 open reading frame 10

chr3_+_193853927 0.689 ENST00000232424.3
HES1
hes family bHLH transcription factor 1
chr19_+_16999654 0.680 ENST00000248076.3
F2RL3
coagulation factor II (thrombin) receptor-like 3
chr16_-_21289627 0.666 ENST00000396023.2
ENST00000415987.2
CRYM

crystallin, mu

chr12_+_71833550 0.655 ENST00000266674.5
LGR5
leucine-rich repeat containing G protein-coupled receptor 5
chr7_-_99573677 0.650 ENST00000292401.4
AZGP1
alpha-2-glycoprotein 1, zinc-binding
chr16_+_57406368 0.626 ENST00000006053.6
ENST00000563383.1
CX3CL1

chemokine (C-X3-C motif) ligand 1

chr19_-_5680202 0.613 ENST00000590389.1
C19orf70
chromosome 19 open reading frame 70
chr1_-_156399184 0.592 ENST00000368243.1
ENST00000357975.4
ENST00000310027.5
ENST00000400991.2
C1orf61



chromosome 1 open reading frame 61



chr1_-_154842741 0.589 ENST00000271915.4
KCNN3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr14_-_24610779 0.588 ENST00000560403.1
ENST00000419198.2
ENST00000216799.4
EMC9


ER membrane protein complex subunit 9


chr9_+_112542591 0.571 ENST00000413420.1
ENST00000302798.7
ENST00000555236.1
ENST00000510514.5
ENST00000483909.1
ENST00000314527.4
PALM2-AKAP2

AKAP2

PALM2

PALM2-AKAP2 readthrough

A kinase (PRKA) anchor protein 2

paralemmin 2

chr1_-_182573514 0.570 ENST00000367558.5
RGS16
regulator of G-protein signaling 16
chr12_+_56473939 0.568 ENST00000450146.2
ERBB3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr12_-_122296755 0.563 ENST00000289004.4
HPD
4-hydroxyphenylpyruvate dioxygenase
chr15_-_20170354 0.552 ENST00000338912.5
IGHV1OR15-9
immunoglobulin heavy variable 1/OR15-9 (non-functional)
chr16_+_15744078 0.548 ENST00000396354.1
ENST00000570727.1
NDE1

nudE neurodevelopment protein 1

chr6_-_11382478 0.528 ENST00000397378.3
ENST00000513989.1
ENST00000508546.1
ENST00000504387.1
NEDD9



neural precursor cell expressed, developmentally down-regulated 9



chr2_+_29336855 0.525 ENST00000404424.1
CLIP4
CAP-GLY domain containing linker protein family, member 4
chr14_-_21567009 0.511 ENST00000556174.1
ENST00000554478.1
ENST00000553980.1
ENST00000421093.2
ZNF219



zinc finger protein 219



chr3_+_111697843 0.500 ENST00000534857.1
ENST00000273359.3
ENST00000494817.1
ABHD10


abhydrolase domain containing 10


chr3_-_149688896 0.497 ENST00000239940.7
PFN2
profilin 2
chr19_-_6670128 0.473 ENST00000245912.3
TNFSF14
tumor necrosis factor (ligand) superfamily, member 14
chr17_-_9929581 0.458 ENST00000437099.2
ENST00000396115.2
GAS7

growth arrest-specific 7

chr14_+_72052983 0.457 ENST00000358550.2
SIPA1L1
signal-induced proliferation-associated 1 like 1
chr3_+_48507210 0.452 ENST00000433541.1
ENST00000422277.2
ENST00000436480.2
ENST00000444177.1
TREX1



three prime repair exonuclease 1



chr11_-_119993734 0.450 ENST00000533302.1
TRIM29
tripartite motif containing 29
chr14_+_21156915 0.450 ENST00000397990.4
ENST00000555597.1
ANG
RNASE4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr16_-_46723066 0.447 ENST00000299138.7
VPS35
vacuolar protein sorting 35 homolog (S. cerevisiae)
chr1_-_24469602 0.442 ENST00000270800.1
IL22RA1
interleukin 22 receptor, alpha 1
chr17_+_45810594 0.441 ENST00000177694.1
TBX21
T-box 21
chr7_-_50628745 0.432 ENST00000380984.4
ENST00000357936.5
ENST00000426377.1
DDC


dopa decarboxylase (aromatic L-amino acid decarboxylase)


chr19_-_36297348 0.429 ENST00000589835.1
PRODH2
proline dehydrogenase (oxidase) 2
chr7_+_99971129 0.425 ENST00000394000.2
ENST00000350573.2
PILRA

paired immunoglobin-like type 2 receptor alpha

chr7_+_90339169 0.417 ENST00000436577.2
CDK14
cyclin-dependent kinase 14
chr18_+_59000815 0.413 ENST00000262717.4
CDH20
cadherin 20, type 2
chr22_+_38453207 0.396 ENST00000404072.3
ENST00000424694.1
PICK1

protein interacting with PRKCA 1

chr1_+_158259558 0.393 ENST00000368170.3
CD1C
CD1c molecule
chr1_-_154832316 0.383 ENST00000361147.4
KCNN3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr20_-_61557821 0.365 ENST00000354665.4
ENST00000370368.1
ENST00000395343.1
ENST00000395340.1
DIDO1



death inducer-obliterator 1



chr19_+_1026566 0.356 ENST00000348419.3
ENST00000565096.2
ENST00000562958.2
ENST00000562075.2
ENST00000607102.1
CNN2




calponin 2




chr11_+_117857063 0.355 ENST00000227752.3
ENST00000541785.1
ENST00000545409.1
IL10RA


interleukin 10 receptor, alpha


chr16_-_24942273 0.354 ENST00000571406.1
ARHGAP17
Rho GTPase activating protein 17
chr12_+_56473910 0.350 ENST00000411731.2
ERBB3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr4_-_141348789 0.347 ENST00000414773.1
CLGN
calmegin
chr10_-_121296045 0.346 ENST00000392865.1
RGS10
regulator of G-protein signaling 10
chr20_+_43104508 0.345 ENST00000262605.4
ENST00000372904.3
TTPAL

tocopherol (alpha) transfer protein-like

chr17_-_3500392 0.343 ENST00000571088.1
ENST00000174621.6
TRPV1

transient receptor potential cation channel, subfamily V, member 1

chr17_+_40714092 0.343 ENST00000420359.1
ENST00000449624.1
ENST00000585811.1
ENST00000585909.1
ENST00000586771.1
ENST00000421097.2
ENST00000591779.1
ENST00000587858.1
ENST00000587214.1
ENST00000587157.1
ENST00000590958.1
ENST00000393818.2
COASY











CoA synthase











chr2_-_220435963 0.337 ENST00000373876.1
ENST00000404537.1
ENST00000603926.1
ENST00000373873.4
ENST00000289656.3
OBSL1




obscurin-like 1




chr14_-_23770683 0.336 ENST00000561437.1
ENST00000559942.1
ENST00000560913.1
ENST00000559314.1
ENST00000558058.1
PPP1R3E




protein phosphatase 1, regulatory subunit 3E




chr6_-_32731243 0.334 ENST00000427449.1
ENST00000411527.1
HLA-DQB2

major histocompatibility complex, class II, DQ beta 2

chr17_-_26941179 0.333 ENST00000301037.5
ENST00000530121.1
ENST00000525510.1
ENST00000577790.1
ENST00000531839.1
ENST00000534850.1
SGK494


RP11-192H23.4


uncharacterized serine/threonine-protein kinase SgK494


Uncharacterized protein


chr5_-_150466692 0.330 ENST00000315050.7
ENST00000523338.1
ENST00000522100.1
TNIP1


TNFAIP3 interacting protein 1


chr11_+_64126614 0.330 ENST00000528057.1
ENST00000334205.4
ENST00000294261.4
RPS6KA4


ribosomal protein S6 kinase, 90kDa, polypeptide 4


chr2_+_201754050 0.329 ENST00000426253.1
ENST00000416651.1
ENST00000454952.1
ENST00000409020.1
ENST00000359683.4
NIF3L1




NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)




chrX_-_31285042 0.323 ENST00000378680.2
ENST00000378723.3
DMD

dystrophin

chr17_-_67138015 0.318 ENST00000284425.2
ENST00000590645.1
ABCA6

ATP-binding cassette, sub-family A (ABC1), member 6

chr16_-_24942411 0.317 ENST00000571843.1
ARHGAP17
Rho GTPase activating protein 17
chrX_+_44732757 0.316 ENST00000377967.4
ENST00000536777.1
ENST00000382899.4
ENST00000543216.1
KDM6A



lysine (K)-specific demethylase 6A



chr22_+_38453378 0.312 ENST00000437453.1
ENST00000356976.3
PICK1

protein interacting with PRKCA 1

chr12_+_50794730 0.311 ENST00000523389.1
ENST00000518561.1
ENST00000347328.5
ENST00000550260.1
LARP4



La ribonucleoprotein domain family, member 4



chr20_-_49547731 0.310 ENST00000396029.3
ADNP
activity-dependent neuroprotector homeobox
chr2_+_201754135 0.303 ENST00000409357.1
ENST00000409129.2
NIF3L1

NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)

chr5_-_115872142 0.302 ENST00000510263.1
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr1_+_205473720 0.300 ENST00000429964.2
ENST00000506784.1
ENST00000360066.2
CDK18


cyclin-dependent kinase 18


chr10_+_6244829 0.299 ENST00000317350.4
ENST00000379785.1
ENST00000379782.3
ENST00000360521.2
ENST00000379775.4
PFKFB3




6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3




chr11_+_64879317 0.296 ENST00000526809.1
ENST00000279263.7
ENST00000524986.1
ENST00000534371.1
ENST00000540748.1
ENST00000525385.1
ENST00000345348.5
ENST00000531321.1
ENST00000529414.1
ENST00000526085.1
ENST00000530750.1
TM7SF2










transmembrane 7 superfamily member 2










chr17_+_55173933 0.294 ENST00000539273.1
AKAP1
A kinase (PRKA) anchor protein 1
chr3_-_48481518 0.291 ENST00000412398.2
ENST00000395696.1
CCDC51

coiled-coil domain containing 51

chr7_-_99573640 0.289 ENST00000411734.1
AZGP1
alpha-2-glycoprotein 1, zinc-binding
chr20_+_55966444 0.288 ENST00000356208.5
ENST00000440234.2
RBM38

RNA binding motif protein 38

chr14_+_61789382 0.282 ENST00000555082.1
PRKCH
protein kinase C, eta
chr14_+_35591735 0.281 ENST00000604948.1
ENST00000605201.1
ENST00000250377.7
ENST00000321130.10
ENST00000534898.4
KIAA0391




KIAA0391




chr3_+_124303472 0.280 ENST00000291478.5
KALRN
kalirin, RhoGEF kinase
chr1_-_173793458 0.278 ENST00000356198.2
CENPL
centromere protein L
chr17_+_4835580 0.278 ENST00000329125.5
GP1BA
glycoprotein Ib (platelet), alpha polypeptide
chr3_+_50192537 0.276 ENST00000002829.3
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr4_-_141348999 0.268 ENST00000325617.5
CLGN
calmegin
chr3_+_50192499 0.265 ENST00000413852.1
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr18_-_6414884 0.258 ENST00000317931.7
ENST00000284898.6
ENST00000400104.3
L3MBTL4


l(3)mbt-like 4 (Drosophila)


chr8_-_95274536 0.257 ENST00000297596.2
ENST00000396194.2
GEM

GTP binding protein overexpressed in skeletal muscle

chr2_-_220436248 0.253 ENST00000265318.4
OBSL1
obscurin-like 1
chr16_-_30457048 0.251 ENST00000500504.2
ENST00000542752.1
SEPHS2

selenophosphate synthetase 2

chr14_-_98444386 0.250 ENST00000556462.1
ENST00000556138.1
C14orf64

chromosome 14 open reading frame 64

chr11_-_22851367 0.249 ENST00000354193.4
SVIP
small VCP/p97-interacting protein
chr2_+_242167319 0.248 ENST00000601871.1
AC104841.2
HCG1777198, isoform CRA_a; PRO2900; Uncharacterized protein
chr18_+_72167096 0.245 ENST00000324301.8
CNDP2
CNDP dipeptidase 2 (metallopeptidase M20 family)
chr15_-_43559055 0.243 ENST00000220420.5
ENST00000349114.4
TGM5

transglutaminase 5

chr12_-_117799446 0.238 ENST00000317775.6
ENST00000344089.3
NOS1

nitric oxide synthase 1 (neuronal)

chrX_-_107681555 0.236 ENST00000545689.1
ENST00000538570.1
COL4A6

collagen, type IV, alpha 6

chr2_+_232572361 0.234 ENST00000409321.1
PTMA
prothymosin, alpha
chrX_+_95939711 0.234 ENST00000373049.4
ENST00000324765.8
DIAPH2

diaphanous-related formin 2

chr12_-_53298841 0.233 ENST00000293308.6
KRT8
keratin 8
chr14_-_74551172 0.229 ENST00000553458.1
ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chrX_-_31284974 0.225 ENST00000378702.4
DMD
dystrophin
chrX_-_31285018 0.223 ENST00000361471.4
DMD
dystrophin
chr1_-_153013588 0.220 ENST00000360379.3
SPRR2D
small proline-rich protein 2D
chr4_+_17579110 0.216 ENST00000606142.1
LAP3
leucine aminopeptidase 3
chrX_+_48660287 0.214 ENST00000444343.2
ENST00000376610.2
ENST00000334136.5
ENST00000376619.2
HDAC6



histone deacetylase 6



chr2_-_85625857 0.214 ENST00000453973.1
CAPG
capping protein (actin filament), gelsolin-like
chr20_-_49547910 0.201 ENST00000396032.3
ADNP
activity-dependent neuroprotector homeobox
chr1_+_93544821 0.201 ENST00000370303.4
MTF2
metal response element binding transcription factor 2
chr12_+_6309517 0.201 ENST00000382519.4
ENST00000009180.4
CD9

CD9 molecule

chr7_+_99971068 0.201 ENST00000198536.2
ENST00000453419.1
PILRA

paired immunoglobin-like type 2 receptor alpha

chr16_+_83986827 0.198 ENST00000393306.1
ENST00000565123.1
OSGIN1

oxidative stress induced growth inhibitor 1

chr15_-_83474806 0.197 ENST00000541889.1
ENST00000334574.8
ENST00000561368.1
FSD2


fibronectin type III and SPRY domain containing 2


chr11_-_77531858 0.196 ENST00000360355.2
RSF1
remodeling and spacing factor 1
chr16_-_27561209 0.196 ENST00000356183.4
ENST00000561623.1
GTF3C1

general transcription factor IIIC, polypeptide 1, alpha 220kDa

chr9_-_131644202 0.195 ENST00000320665.6
ENST00000436267.2
CCBL1

cysteine conjugate-beta lyase, cytoplasmic

chr12_+_6309963 0.195 ENST00000382515.2
CD9
CD9 molecule
chr2_+_145780767 0.195 ENST00000599358.1
ENST00000596278.1
ENST00000596747.1
ENST00000608652.1
ENST00000609705.1
ENST00000608432.1
ENST00000596970.1
ENST00000602041.1
ENST00000601578.1
ENST00000596034.1
ENST00000414195.2
ENST00000594837.1
TEX41











testis expressed 41 (non-protein coding)











chr1_+_147374915 0.194 ENST00000240986.4
GJA8
gap junction protein, alpha 8, 50kDa
chr5_+_78407602 0.194 ENST00000274353.5
ENST00000524080.1
BHMT

betaine--homocysteine S-methyltransferase

chr12_+_57984965 0.194 ENST00000540759.2
ENST00000551772.1
ENST00000550465.1
ENST00000354947.5
PIP4K2C



phosphatidylinositol-5-phosphate 4-kinase, type II, gamma



chr12_+_71833756 0.189 ENST00000536515.1
ENST00000540815.2
LGR5

leucine-rich repeat containing G protein-coupled receptor 5

chr7_+_29237354 0.188 ENST00000546235.1
CHN2
chimerin 2
chr19_-_6767516 0.188 ENST00000245908.6
SH2D3A
SH2 domain containing 3A
chr20_+_42839722 0.186 ENST00000442383.1
ENST00000435163.1
OSER1-AS1

OSER1 antisense RNA 1 (head to head)

chr2_+_28974668 0.186 ENST00000296122.6
ENST00000395366.2
PPP1CB

protein phosphatase 1, catalytic subunit, beta isozyme

chr7_+_129007964 0.185 ENST00000460109.1
ENST00000474594.1
ENST00000446212.1
AHCYL2


adenosylhomocysteinase-like 2


chrX_-_119445306 0.185 ENST00000371369.4
ENST00000440464.1
ENST00000519908.1
TMEM255A


transmembrane protein 255A


chr17_+_58755184 0.183 ENST00000589222.1
ENST00000407086.3
ENST00000390652.5
BCAS3


breast carcinoma amplified sequence 3


chr17_+_66521936 0.179 ENST00000592800.1
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr9_-_22009241 0.179 ENST00000380142.4
CDKN2B
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
chr22_-_42343117 0.178 ENST00000407253.3
ENST00000215980.5
CENPM

centromere protein M

chr12_+_50135351 0.174 ENST00000549445.1
ENST00000550951.1
ENST00000549385.1
ENST00000548713.1
ENST00000548201.1
TMBIM6




transmembrane BAX inhibitor motif containing 6




chr16_+_55690002 0.174 ENST00000414754.3
SLC6A2
solute carrier family 6 (neurotransmitter transporter), member 2
chr14_-_90798418 0.174 ENST00000354366.3
NRDE2
NRDE-2, necessary for RNA interference, domain containing
chr6_+_166945369 0.170 ENST00000598601.1
Z98049.1
CDNA FLJ25492 fis, clone CBR01389; Uncharacterized protein
chr5_+_176853702 0.170 ENST00000507633.1
ENST00000393576.3
ENST00000355958.5
ENST00000528793.1
ENST00000512684.1
GRK6




G protein-coupled receptor kinase 6




chr12_-_54978086 0.169 ENST00000553113.1
PPP1R1A
protein phosphatase 1, regulatory (inhibitor) subunit 1A
chr3_-_52443799 0.169 ENST00000470173.1
ENST00000296288.5
BAP1

BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)

chr14_-_35344093 0.168 ENST00000382422.2
BAZ1A
bromodomain adjacent to zinc finger domain, 1A
chr16_+_30671223 0.166 ENST00000568722.1
FBRS
fibrosin
chr10_-_99531709 0.163 ENST00000266066.3
SFRP5
secreted frizzled-related protein 5
chr16_-_47177874 0.162 ENST00000562435.1
NETO2
neuropilin (NRP) and tolloid (TLL)-like 2
chr12_+_50135327 0.161 ENST00000549966.1
ENST00000547832.1
ENST00000547187.1
ENST00000548894.1
ENST00000546914.1
ENST00000552699.1
ENST00000267115.5
TMBIM6






transmembrane BAX inhibitor motif containing 6






chr4_+_75023816 0.159 ENST00000395759.2
ENST00000331145.6
ENST00000359107.5
ENST00000325278.6
MTHFD2L



methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like



chr12_-_10151773 0.155 ENST00000298527.6
ENST00000348658.4
CLEC1B

C-type lectin domain family 1, member B

chr14_+_50779029 0.152 ENST00000245448.6
ATP5S
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
chr5_-_150521192 0.151 ENST00000523714.1
ENST00000521749.1
ANXA6

annexin A6

chr7_+_16828866 0.147 ENST00000597084.1
AC073333.1
Uncharacterized protein
chr9_-_22009297 0.146 ENST00000276925.6
CDKN2B
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
chr11_-_67290867 0.146 ENST00000353903.5
ENST00000294288.4
CABP2

calcium binding protein 2

chr1_+_93544791 0.145 ENST00000545708.1
ENST00000540243.1
ENST00000370298.4
MTF2


metal response element binding transcription factor 2


chr1_+_109792641 0.144 ENST00000271332.3
CELSR2
cadherin, EGF LAG seven-pass G-type receptor 2
chr7_+_29234375 0.144 ENST00000409350.1
ENST00000495789.2
ENST00000539389.1
CHN2


chimerin 2


chr21_-_16437255 0.143 ENST00000400199.1
ENST00000400202.1
NRIP1

nuclear receptor interacting protein 1

chr14_+_45553296 0.141 ENST00000355765.6
ENST00000553605.1
PRPF39

pre-mRNA processing factor 39

chr11_+_67250490 0.141 ENST00000528641.2
ENST00000279146.3
AIP

aryl hydrocarbon receptor interacting protein

chr5_-_160279207 0.140 ENST00000327245.5
ATP10B
ATPase, class V, type 10B
chr2_-_25565377 0.139 ENST00000264709.3
ENST00000406659.3
DNMT3A

DNA (cytosine-5-)-methyltransferase 3 alpha

chr17_-_74137374 0.138 ENST00000322957.6
FOXJ1
forkhead box J1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.4 1.7 GO:0001969 activation of membrane attack complex(GO:0001905) regulation of activation of membrane attack complex(GO:0001969) positive regulation of activation of membrane attack complex(GO:0001970) positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.4 1.2 GO:0061117 negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of cardiac muscle tissue development(GO:0055026) negative regulation of cardiac muscle cell proliferation(GO:0060044) negative regulation of heart growth(GO:0061117)
0.3 1.4 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
0.3 1.3 GO:0046967 cytosol to ER transport(GO:0046967)
0.3 0.9 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.3 1.8 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.2 1.0 GO:0051712 positive regulation of killing of cells of other organism(GO:0051712)
0.2 0.7 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.2 0.6 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.2 4.0 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.2 0.7 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.2 2.1 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.1 0.8 GO:0043045 DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.1 9.8 GO:0030183 B cell differentiation(GO:0030183)
0.1 0.6 GO:0060049 regulation of protein ADP-ribosylation(GO:0010835) regulation of protein glycosylation(GO:0060049)
0.1 0.5 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1 0.3 GO:0060454 positive regulation of gastric acid secretion(GO:0060454) regulation of establishment of blood-brain barrier(GO:0090210) negative regulation of establishment of blood-brain barrier(GO:0090212)
0.1 0.4 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.1 1.0 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1 0.4 GO:0030913 paranodal junction assembly(GO:0030913)
0.1 0.7 GO:0060155 platelet dense granule organization(GO:0060155)
0.1 0.5 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.1 0.3 GO:0001543 ovarian follicle rupture(GO:0001543)
0.1 0.2 GO:0060028 convergent extension involved in axis elongation(GO:0060028) negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1 0.6 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 1.3 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.1 0.5 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.1 0.2 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.1 0.5 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.1 0.7 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 0.3 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.1 0.4 GO:0006562 proline catabolic process(GO:0006562)
0.1 0.2 GO:0090034 peptidyl-lysine deacetylation(GO:0034983) regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
0.1 0.1 GO:0002890 negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890) negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.1 0.5 GO:0051294 establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.1 0.9 GO:0061098 positive regulation of protein tyrosine kinase activity(GO:0061098)
0.1 0.7 GO:0098927 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.1 1.0 GO:1904031 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.1 1.4 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.1 0.4 GO:0042416 dopamine biosynthetic process(GO:0042416)
0.1 0.6 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.1 0.3 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1 0.5 GO:0097061 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0 0.3 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.3 GO:0010648 negative regulation of signal transduction(GO:0009968) negative regulation of cell communication(GO:0010648) negative regulation of signaling(GO:0023057) negative regulation of response to stimulus(GO:0048585)
0.0 0.1 GO:0060896 neural plate anterior/posterior regionalization(GO:0021999) neural plate pattern specification(GO:0060896) neural plate regionalization(GO:0060897)
0.0 0.3 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.3 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 1.4 GO:0019882 antigen processing and presentation(GO:0019882)
0.0 3.4 GO:0042113 B cell activation(GO:0042113)
0.0 0.1 GO:0043163 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.0 0.1 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.0 0.3 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.6 GO:0035036 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036)
0.0 0.2 GO:0010523 negative regulation of calcium ion transport into cytosol(GO:0010523)
0.0 0.1 GO:0071312 cellular response to alkaloid(GO:0071312) cellular response to caffeine(GO:0071313)
0.0 0.5 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843) negative chemotaxis(GO:0050919)
0.0 0.2 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.2 GO:0050666 regulation of sulfur amino acid metabolic process(GO:0031335) regulation of homocysteine metabolic process(GO:0050666)
0.0 0.1 GO:0019056 modulation by virus of host transcription(GO:0019056) regulation of sprouting of injured axon(GO:0048686) positive regulation of sprouting of injured axon(GO:0048687) regulation of axon extension involved in regeneration(GO:0048690) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.0 0.1 GO:0048865 stem cell fate commitment(GO:0048865) stem cell fate determination(GO:0048867)
0.0 0.2 GO:0042797 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0 0.1 GO:0060259 regulation of feeding behavior(GO:0060259)
0.0 0.2 GO:0006558 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.0 0.3 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.3 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.0 0.2 GO:0009396 histidine metabolic process(GO:0006547) folic acid-containing compound biosynthetic process(GO:0009396)
0.0 0.3 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.1 GO:0022417 protein maturation by protein folding(GO:0022417)
0.0 2.3 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.1 GO:0030277 epithelial structure maintenance(GO:0010669) maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.5 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.1 GO:0060398 regulation of growth hormone receptor signaling pathway(GO:0060398)
0.0 0.5 GO:0006298 mismatch repair(GO:0006298)
0.0 0.1 GO:0072148 epithelial cell fate commitment(GO:0072148)
0.0 0.1 GO:0006622 protein targeting to lysosome(GO:0006622) protein targeting to vacuole(GO:0006623) protein localization to lysosome(GO:0061462) protein localization to vacuole(GO:0072665) establishment of protein localization to vacuole(GO:0072666)
0.0 0.1 GO:0061081 positive regulation of macrophage cytokine production(GO:0060907) positive regulation of myeloid leukocyte cytokine production involved in immune response(GO:0061081)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 1.1 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
0.0 0.2 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.1 GO:0060113 inner ear receptor cell differentiation(GO:0060113)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.3 GO:0009070 serine family amino acid biosynthetic process(GO:0009070)
0.0 0.7 GO:0017156 calcium ion regulated exocytosis(GO:0017156)
0.0 0.2 GO:0048265 response to pain(GO:0048265)
0.0 0.3 GO:0031424 keratinization(GO:0031424)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 6.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.2 1.6 GO:0005587 collagen type IV trimer(GO:0005587)
0.2 0.6 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.2 0.7 GO:0070695 FHF complex(GO:0070695)
0.2 1.3 GO:0042825 TAP complex(GO:0042825)
0.1 0.9 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.1 0.3 GO:0031213 RSF complex(GO:0031213)
0.1 2.4 GO:0042611 MHC protein complex(GO:0042611)
0.1 0.5 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.1 0.5 GO:0042587 glycogen granule(GO:0042587)
0.1 0.5 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 0.6 GO:0031430 M band(GO:0031430)
0.1 1.0 GO:0005922 connexon complex(GO:0005922)
0.0 0.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 1.4 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.8 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.2 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 1.0 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.9 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.7 GO:0009925 basal plasma membrane(GO:0009925)
0.0 1.4 GO:0005902 microvillus(GO:0005902)
0.0 0.1 GO:0010370 perinucleolar chromocenter(GO:0010370)
0.0 0.7 GO:0043034 costamere(GO:0043034)
0.0 0.2 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.2 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.3 GO:0030061 mitochondrial crista(GO:0030061)
0.0 4.5 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 0.2 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.2 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.1 GO:0030897 HOPS complex(GO:0030897)
0.0 1.0 GO:0005626 obsolete insoluble fraction(GO:0005626)
0.0 0.7 GO:0005884 actin filament(GO:0005884)
0.0 0.2 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.5 GO:0005911 cell-cell junction(GO:0005911)
0.0 0.2 GO:0016235 aggresome(GO:0016235)
0.0 2.0 GO:0019717 obsolete synaptosome(GO:0019717)
0.0 0.3 GO:0019867 mitochondrial outer membrane(GO:0005741) outer membrane(GO:0019867) organelle outer membrane(GO:0031968)
0.0 0.1 GO:0000791 euchromatin(GO:0000791)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.1 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 9.8 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.8 2.3 GO:0042289 MHC class II protein binding(GO:0042289)
0.3 4.0 GO:0032395 MHC class II receptor activity(GO:0032395)
0.3 1.3 GO:0046980 oligopeptide-transporting ATPase activity(GO:0015421) tapasin binding(GO:0046980)
0.2 1.0 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.2 0.7 GO:0043398 HLH domain binding(GO:0043398)
0.2 0.7 GO:0070324 thyroid hormone binding(GO:0070324)
0.2 1.0 GO:0019863 IgE binding(GO:0019863)
0.2 1.0 GO:0015057 thrombin receptor activity(GO:0015057)
0.1 1.8 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 0.4 GO:0071723 lipopeptide binding(GO:0071723)
0.1 0.5 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.4 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.1 0.7 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 1.2 GO:0019841 retinol binding(GO:0019841)
0.1 0.9 GO:0042153 obsolete RPTP-like protein binding(GO:0042153) alpha-catenin binding(GO:0045294)
0.1 0.3 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.1 1.4 GO:0032393 MHC class I receptor activity(GO:0032393)
0.1 0.5 GO:0032558 purine deoxyribonucleotide binding(GO:0032554) adenyl deoxyribonucleotide binding(GO:0032558)
0.1 0.3 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.1 1.2 GO:0042605 peptide antigen binding(GO:0042605)
0.1 0.3 GO:0004756 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.1 2.8 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 1.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.8 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.9 GO:0005243 gap junction channel activity(GO:0005243)
0.1 0.2 GO:0047150 betaine-homocysteine S-methyltransferase activity(GO:0047150)
0.1 0.2 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.2 GO:0034701 tripeptidase activity(GO:0034701)
0.1 0.2 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 1.4 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 0.5 GO:0004969 histamine receptor activity(GO:0004969)
0.1 0.5 GO:0004522 ribonuclease A activity(GO:0004522)
0.1 0.9 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 0.2 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.1 1.0 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 0.2 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477)
0.0 0.3 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.2 GO:0070548 1-aminocyclopropane-1-carboxylate synthase activity(GO:0016847) L-glutamine aminotransferase activity(GO:0070548)
0.0 0.8 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 1.3 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.3 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.4 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.2 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.4 GO:0004904 interferon receptor activity(GO:0004904)
0.0 0.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 1.0 GO:0019003 GDP binding(GO:0019003)
0.0 0.3 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.2 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.2 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.6 GO:0030332 cyclin binding(GO:0030332)
0.0 0.6 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.0 1.1 GO:0003823 antigen binding(GO:0003823)
0.0 0.1 GO:0015187 glycine transmembrane transporter activity(GO:0015187) glycine:sodium symporter activity(GO:0015375)
0.0 0.2 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.2 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.0 4.2 GO:0004866 endopeptidase inhibitor activity(GO:0004866) endopeptidase regulator activity(GO:0061135)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.7 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.2 GO:0003709 obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0 0.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.3 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.2 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 1.0 GO:0008017 microtubule binding(GO:0008017)
0.0 0.1 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 9.8 SA_B_CELL_RECEPTOR_COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 1.4 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.7 ST_GA12_PATHWAY G alpha 12 Pathway
0.0 0.1 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.