ISMARA results: NOTO_VSX2_DLX2_DLX6

Motif ID: NOTO_VSX2_DLX2_DLX6_NKX6-1

Z-value: 0.733

Transcription factors associated with NOTO_VSX2_DLX2_DLX6_NKX6-1:

Gene Symbol	Entrez ID	Gene Name
DLX2	ENSG00000115844.6	DLX2
DLX6	ENSG00000006377.9	DLX6
NKX6-1	ENSG00000163623.5	NKX6-1
NOTO	ENSG00000214513.3	NOTO
VSX2	ENSG00000119614.2	VSX2

Sorted Z-values for motif NOTO_VSX2_DLX2_DLX6_NKX6-1

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr12_+_81110684	2.838	ENST00000228644.3	MYF5	myogenic factor 5
chr12_-_6233828	1.158	ENST00000572068.1 ENST00000261405.5	VWF	von Willebrand factor
chr7_-_107642348	1.063	ENST00000393561.1	LAMB1	laminin, beta 1
chr3_+_157154578	0.955	ENST00000295927.3	PTX3	pentraxin 3, long
chr5_+_53751445	0.914	ENST00000302005.1	HSPB3	heat shock 27kDa protein 3
chr17_-_77924627	0.798	ENST00000572862.1 ENST00000573782.1 ENST00000574427.1 ENST00000570373.1 ENST00000340848.7 ENST00000576768.1	TBC1D16	TBC1 domain family, member 16
chr4_-_111563076	0.786	ENST00000354925.2 ENST00000511990.1	PITX2	paired-like homeodomain 2
chr4_-_186696425	0.757	ENST00000430503.1 ENST00000319454.6 ENST00000450341.1	SORBS2	sorbin and SH3 domain containing 2
chr2_-_145278475	0.732	ENST00000558170.2	ZEB2	zinc finger E-box binding homeobox 2
chr12_-_16761007	0.700	ENST00000354662.1 ENST00000441439.2	LMO3	LIM domain only 3 (rhombotin-like 2)
chr11_-_33913708	0.690	ENST00000257818.2	LMO2	LIM domain only 2 (rhombotin-like 1)
chr6_-_32157947	0.685	ENST00000375050.4	PBX2	pre-B-cell leukemia homeobox 2
chr2_-_190927447	0.581	ENST00000260950.4	MSTN	myostatin
chr17_-_10421853	0.572	ENST00000226207.5	MYH1	myosin, heavy chain 1, skeletal muscle, adult
chr1_-_227505289	0.546	ENST00000366765.3	CDC42BPA	CDC42 binding protein kinase alpha (DMPK-like)
chr12_+_54378923	0.531	ENST00000303460.4	HOXC10	homeobox C10
chr13_-_36788718	0.523	ENST00000317764.6 ENST00000379881.3	SOHLH2	spermatogenesis and oogenesis specific basic helix-loop-helix 2
chr7_+_73442487	0.515	ENST00000380575.4 ENST00000380584.4 ENST00000458204.1 ENST00000357036.5 ENST00000417091.1 ENST00000429192.1 ENST00000442310.1 ENST00000380553.4 ENST00000380576.5 ENST00000428787.1 ENST00000320399.6	ELN	elastin
chr10_-_92681033	0.486	ENST00000371697.3	ANKRD1	ankyrin repeat domain 1 (cardiac muscle)
chr7_+_73442422	0.471	ENST00000358929.4 ENST00000431562.1 ENST00000320492.7 ENST00000438906.1	ELN	elastin
chr3_+_159557637	0.458	ENST00000445224.2	SCHIP1	schwannomin interacting protein 1
chr4_+_169418195	0.449	ENST00000261509.6 ENST00000335742.7	PALLD	palladin, cytoskeletal associated protein
chr3_+_173116225	0.436	ENST00000457714.1	NLGN1	neuroligin 1
chr21_-_40033618	0.400	ENST00000417133.2 ENST00000398910.1 ENST00000442448.1	ERG	v-ets avian erythroblastosis virus E26 oncogene homolog
chr4_+_41614909	0.396	ENST00000509454.1 ENST00000396595.3 ENST00000381753.4	LIMCH1	LIM and calponin homology domains 1
chr18_-_53089723	0.386	ENST00000561992.1 ENST00000562512.2	TCF4	transcription factor 4
chr7_+_73442457	0.380	ENST00000438880.1 ENST00000414324.1 ENST00000380562.4	ELN	elastin
chr3_-_114477787	0.379	ENST00000464560.1	ZBTB20	zinc finger and BTB domain containing 20
chr6_+_151646800	0.367	ENST00000354675.6	AKAP12	A kinase (PRKA) anchor protein 12
chr3_+_35722487	0.359	ENST00000441454.1	ARPP21	cAMP-regulated phosphoprotein, 21kDa
chr11_-_2160180	0.351	ENST00000381406.4	IGF2	insulin-like growth factor 2 (somatomedin A)
chr19_+_50016411	0.350	ENST00000426395.3 ENST00000600273.1 ENST00000599988.1	FCGRT	Fc fragment of IgG, receptor, transporter, alpha
chr7_+_73442102	0.325	ENST00000445912.1 ENST00000252034.7	ELN	elastin
chr13_-_67802549	0.311	ENST00000328454.5 ENST00000377865.2	PCDH9	protocadherin 9
chr12_+_26348582	0.310	ENST00000535504.1	SSPN	sarcospan
chr3_-_114477962	0.306	ENST00000471418.1	ZBTB20	zinc finger and BTB domain containing 20
chr5_+_174151536	0.305	ENST00000239243.6 ENST00000507785.1	MSX2	msh homeobox 2
chr17_-_64225508	0.303	ENST00000205948.6	APOH	apolipoprotein H (beta-2-glycoprotein I)
chr12_-_16759711	0.282	ENST00000447609.1	LMO3	LIM domain only 3 (rhombotin-like 2)
chr12_+_81101277	0.273	ENST00000228641.3	MYF6	myogenic factor 6 (herculin)
chr2_-_175711133	0.270	ENST00000409597.1 ENST00000413882.1	CHN1	chimerin 1
chr7_-_27205136	0.268	ENST00000396345.1 ENST00000343483.6	HOXA9	homeobox A9
chr6_-_36515177	0.268	ENST00000229812.7	STK38	serine/threonine kinase 38
chr12_-_30887948	0.260	ENST00000433722.2	CAPRIN2	caprin family member 2
chr3_+_35721106	0.258	ENST00000474696.1 ENST00000412048.1 ENST00000396482.2 ENST00000432682.1	ARPP21	cAMP-regulated phosphoprotein, 21kDa
chr7_-_27169801	0.257	ENST00000511914.1	HOXA4	homeobox A4
chr10_-_75415825	0.250	ENST00000394810.2	SYNPO2L	synaptopodin 2-like
chr19_+_50016610	0.243	ENST00000596975.1	FCGRT	Fc fragment of IgG, receptor, transporter, alpha
chr12_-_71031185	0.242	ENST00000548122.1 ENST00000551525.1 ENST00000550358.1	PTPRB	protein tyrosine phosphatase, receptor type, B
chr9_+_470288	0.238	ENST00000382303.1	KANK1	KN motif and ankyrin repeat domains 1
chr7_-_151217166	0.237	ENST00000496004.1	RHEB	Ras homolog enriched in brain
chr12_+_26348246	0.237	ENST00000422622.2	SSPN	sarcospan
chr3_-_141747950	0.236	ENST00000497579.1	TFDP2	transcription factor Dp-2 (E2F dimerization partner 2)
chr17_+_48243352	0.228	ENST00000344627.6 ENST00000262018.3 ENST00000543315.1 ENST00000451235.2 ENST00000511303.1	SGCA	sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)
chr8_+_50824233	0.228	ENST00000522124.1	SNTG1	syntrophin, gamma 1
chr12_+_26348429	0.225	ENST00000242729.2	SSPN	sarcospan
chr17_-_10325261	0.222	ENST00000403437.2	MYH8	myosin, heavy chain 8, skeletal muscle, perinatal
chr10_+_17270214	0.217	ENST00000544301.1	VIM	vimentin
chr13_+_102104980	0.217	ENST00000545560.2	ITGBL1	integrin, beta-like 1 (with EGF-like repeat domains)
chr22_-_36236623	0.216	ENST00000405409.2	RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2
chr4_+_3388057	0.215	ENST00000538395.1	RGS12	regulator of G-protein signaling 12
chr4_-_74486217	0.209	ENST00000335049.5 ENST00000307439.5	RASSF6	Ras association (RalGDS/AF-6) domain family member 6
chr3_+_158787041	0.208	ENST00000471575.1 ENST00000476809.1 ENST00000485419.1	IQCJ-SCHIP1	IQCJ-SCHIP1 readthrough
chr13_-_110438914	0.208	ENST00000375856.3	IRS2	insulin receptor substrate 2
chr3_-_114790179	0.200	ENST00000462705.1	ZBTB20	zinc finger and BTB domain containing 20
chr8_+_77593448	0.199	ENST00000521891.2	ZFHX4	zinc finger homeobox 4
chr3_-_178984759	0.197	ENST00000349697.2 ENST00000497599.1	KCNMB3	potassium large conductance calcium-activated channel, subfamily M beta member 3
chr3_+_158991025	0.190	ENST00000337808.6	IQCJ-SCHIP1	IQCJ-SCHIP1 readthrough
chr3_-_149293990	0.188	ENST00000472417.1	WWTR1	WW domain containing transcription regulator 1
chr2_+_187454749	0.187	ENST00000261023.3 ENST00000374907.3	ITGAV	integrin, alpha V
chr8_+_77593474	0.186	ENST00000455469.2 ENST00000050961.6	ZFHX4	zinc finger homeobox 4
chr2_+_169757750	0.186	ENST00000375363.3 ENST00000429379.2 ENST00000421979.1	G6PC2	glucose-6-phosphatase, catalytic, 2
chr16_-_28621298	0.185	ENST00000566189.1	SULT1A1	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chrX_-_106243451	0.181	ENST00000355610.4 ENST00000535534.1	MORC4	MORC family CW-type zinc finger 4
chr10_+_124320156	0.179	ENST00000338354.3 ENST00000344338.3 ENST00000330163.4 ENST00000368909.3 ENST00000368955.3 ENST00000368956.2	DMBT1	deleted in malignant brain tumors 1
chr15_+_58702742	0.177	ENST00000356113.6 ENST00000414170.3	LIPC	lipase, hepatic
chr17_-_10452929	0.177	ENST00000532183.2 ENST00000397183.2 ENST00000420805.1	MYH2	myosin, heavy chain 2, skeletal muscle, adult
chr1_+_62439037	0.177	ENST00000545929.1	INADL	InaD-like (Drosophila)
chr11_-_129062093	0.176	ENST00000310343.9	ARHGAP32	Rho GTPase activating protein 32
chr16_+_22501658	0.174	ENST00000415833.2	NPIPB5	nuclear pore complex interacting protein family, member B5
chr22_-_36236265	0.173	ENST00000414461.2 ENST00000416721.2 ENST00000449924.2 ENST00000262829.7 ENST00000397305.3	RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2
chr2_-_145277569	0.173	ENST00000303660.4	ZEB2	zinc finger E-box binding homeobox 2
chr13_-_88323218	0.173	ENST00000436290.2 ENST00000453832.2 ENST00000606590.1	MIR4500HG	MIR4500 host gene (non-protein coding)
chr10_+_124320195	0.172	ENST00000359586.6	DMBT1	deleted in malignant brain tumors 1
chr4_+_71457970	0.170	ENST00000322937.6	AMBN	ameloblastin (enamel matrix protein)
chr13_+_102104952	0.166	ENST00000376180.3	ITGBL1	integrin, beta-like 1 (with EGF-like repeat domains)
chr18_-_53069419	0.161	ENST00000570177.2	TCF4	transcription factor 4
chr2_-_145275228	0.160	ENST00000427902.1 ENST00000409487.3 ENST00000470879.1 ENST00000435831.1	ZEB2	zinc finger E-box binding homeobox 2
chr12_-_89746173	0.158	ENST00000308385.6	DUSP6	dual specificity phosphatase 6
chr12_-_51422017	0.158	ENST00000394904.3	SLC11A2	solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
chrX_+_135251783	0.156	ENST00000394153.2	FHL1	four and a half LIM domains 1
chr7_-_143599207	0.154	ENST00000355951.2 ENST00000479870.1 ENST00000478172.1	FAM115A	family with sequence similarity 115, member A
chr21_-_35899113	0.151	ENST00000492600.1 ENST00000481448.1 ENST00000381132.2	RCAN1	regulator of calcineurin 1
chr16_-_29910853	0.151	ENST00000308713.5	SEZ6L2	seizure related 6 homolog (mouse)-like 2
chr16_-_28621312	0.151	ENST00000314752.7	SULT1A1	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr6_-_49604545	0.150	ENST00000371175.4 ENST00000229810.7	RHAG	Rh-associated glycoprotein
chr4_+_86396265	0.149	ENST00000395184.1	ARHGAP24	Rho GTPase activating protein 24
chr6_-_100912785	0.149	ENST00000369208.3	SIM1	single-minded family bHLH transcription factor 1
chr20_-_56285595	0.147	ENST00000395816.3 ENST00000347215.4	PMEPA1	prostate transmembrane protein, androgen induced 1
chr12_-_71031220	0.146	ENST00000334414.6	PTPRB	protein tyrosine phosphatase, receptor type, B
chr16_-_28621353	0.145	ENST00000567512.1	SULT1A1	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr7_+_138145076	0.138	ENST00000343526.4	TRIM24	tripartite motif containing 24
chr9_+_136501478	0.134	ENST00000393056.2 ENST00000263611.2	DBH	dopamine beta-hydroxylase (dopamine beta-monooxygenase)
chr16_+_69345243	0.134	ENST00000254950.11	VPS4A	vacuolar protein sorting 4 homolog A (S. cerevisiae)
chr2_-_152589670	0.134	ENST00000604864.1 ENST00000603639.1	NEB	nebulin
chr2_+_109204743	0.134	ENST00000332345.6	LIMS1	LIM and senescent cell antigen-like domains 1
chr6_-_91296602	0.134	ENST00000369325.3 ENST00000369327.3	MAP3K7	mitogen-activated protein kinase kinase kinase 7
chr7_-_151217001	0.133	ENST00000262187.5	RHEB	Ras homolog enriched in brain
chr11_+_71900703	0.133	ENST00000393681.2	FOLR1	folate receptor 1 (adult)
chr9_-_13165457	0.132	ENST00000542239.1 ENST00000538841.1 ENST00000433359.2	MPDZ	multiple PDZ domain protein
chr14_-_61116168	0.131	ENST00000247182.6	SIX1	SIX homeobox 1
chrX_+_135251835	0.129	ENST00000456445.1	FHL1	four and a half LIM domains 1
chr11_+_71900572	0.129	ENST00000312293.4	FOLR1	folate receptor 1 (adult)
chr4_-_74486347	0.129	ENST00000342081.3	RASSF6	Ras association (RalGDS/AF-6) domain family member 6
chr6_-_91296737	0.127	ENST00000369332.3 ENST00000369329.3	MAP3K7	mitogen-activated protein kinase kinase kinase 7
chr15_+_91411810	0.126	ENST00000268171.3	FURIN	furin (paired basic amino acid cleaving enzyme)
chr1_+_36621529	0.118	ENST00000316156.4	MAP7D1	MAP7 domain containing 1
chrX_+_135252050	0.117	ENST00000449474.1 ENST00000345434.3	FHL1	four and a half LIM domains 1
chr12_+_21207503	0.117	ENST00000545916.1	SLCO1B7	solute carrier organic anion transporter family, member 1B7 (non-functional)
chr1_+_206557366	0.115	ENST00000414007.1 ENST00000419187.2	SRGAP2	SLIT-ROBO Rho GTPase activating protein 2
chr3_-_157824292	0.112	ENST00000483851.2	SHOX2	short stature homeobox 2
chr9_-_136933134	0.112	ENST00000303407.7	BRD3	bromodomain containing 3
chr6_-_161695042	0.112	ENST00000366908.5 ENST00000366911.5 ENST00000366905.3	AGPAT4	1-acylglycerol-3-phosphate O-acyltransferase 4
chr21_-_39870339	0.110	ENST00000429727.2 ENST00000398905.1 ENST00000398907.1 ENST00000453032.2 ENST00000288319.7	ERG	v-ets avian erythroblastosis virus E26 oncogene homolog
chr7_-_99717463	0.110	ENST00000437822.2	TAF6	TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr18_-_53257027	0.107	ENST00000568740.1 ENST00000564403.2 ENST00000537578.1	TCF4	transcription factor 4
chr6_-_31107127	0.106	ENST00000259845.4	PSORS1C2	psoriasis susceptibility 1 candidate 2
chrX_-_20236970	0.106	ENST00000379548.4	RPS6KA3	ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr1_-_94147385	0.103	ENST00000260502.6	BCAR3	breast cancer anti-estrogen resistance 3
chr18_-_53177984	0.100	ENST00000543082.1	TCF4	transcription factor 4
chr14_-_78083112	0.098	ENST00000216484.2	SPTLC2	serine palmitoyltransferase, long chain base subunit 2
chr12_+_49621658	0.097	ENST00000541364.1	TUBA1C	tubulin, alpha 1c
chr1_-_68698222	0.096	ENST00000370976.3 ENST00000354777.2 ENST00000262348.4 ENST00000540432.1	WLS	wntless Wnt ligand secretion mediator
chr1_-_101360331	0.096	ENST00000416479.1 ENST00000370113.3	EXTL2	exostosin-like glycosyltransferase 2
chr12_-_56694142	0.096	ENST00000550655.1 ENST00000548567.1 ENST00000551430.2 ENST00000351328.3	CS	citrate synthase
chr19_+_13049413	0.095	ENST00000316448.5 ENST00000588454.1	CALR	calreticulin
chr14_-_101295407	0.095	ENST00000596284.1	AL117190.2	AL117190.2
chrX_-_64196351	0.094	ENST00000374839.3	ZC4H2	zinc finger, C4H2 domain containing
chr11_+_125034586	0.094	ENST00000298282.9	PKNOX2	PBX/knotted 1 homeobox 2
chr15_-_31393910	0.094	ENST00000397795.2 ENST00000256552.6 ENST00000559179.1	TRPM1	transient receptor potential cation channel, subfamily M, member 1
chr7_-_99716952	0.092	ENST00000523306.1 ENST00000344095.4 ENST00000417349.1 ENST00000493322.1 ENST00000520135.1 ENST00000418432.2 ENST00000460673.2 ENST00000452041.1 ENST00000452438.2 ENST00000451699.1 ENST00000453269.2	TAF6	TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr9_-_14314518	0.091	ENST00000397581.2	NFIB	nuclear factor I/B
chr9_-_14314566	0.091	ENST00000397579.2	NFIB	nuclear factor I/B
chr14_+_22977587	0.088	ENST00000390504.1	TRAJ33	T cell receptor alpha joining 33
chr14_+_61654271	0.086	ENST00000555185.1 ENST00000557294.1 ENST00000556778.1	PRKCH	protein kinase C, eta
chr17_+_48823975	0.086	ENST00000513969.1 ENST00000503728.1	LUC7L3	LUC7-like 3 (S. cerevisiae)
chr16_-_66764119	0.086	ENST00000569320.1	DYNC1LI2	dynein, cytoplasmic 1, light intermediate chain 2
chr3_-_58613323	0.085	ENST00000474531.1 ENST00000465970.1	FAM107A	family with sequence similarity 107, member A
chr5_+_66300446	0.085	ENST00000261569.7	MAST4	microtubule associated serine/threonine kinase family member 4
chr2_+_201173667	0.084	ENST00000409755.3	SPATS2L	spermatogenesis associated, serine-rich 2-like
chr1_-_94079648	0.083	ENST00000370247.3	BCAR3	breast cancer anti-estrogen resistance 3
chr11_-_13517565	0.081	ENST00000282091.1 ENST00000529816.1	PTH	parathyroid hormone
chr4_+_41614720	0.081	ENST00000509277.1	LIMCH1	LIM and calponin homology domains 1
chr15_+_89631381	0.080	ENST00000352732.5	ABHD2	abhydrolase domain containing 2
chr8_+_26150628	0.079	ENST00000523925.1 ENST00000315985.7	PPP2R2A	protein phosphatase 2, regulatory subunit B, alpha
chr6_-_161695074	0.078	ENST00000457520.2 ENST00000366906.5 ENST00000320285.4	AGPAT4	1-acylglycerol-3-phosphate O-acyltransferase 4
chr2_-_55237484	0.078	ENST00000394609.2	RTN4	reticulon 4
chr2_+_171034646	0.076	ENST00000409044.3 ENST00000408978.4	MYO3B	myosin IIIB
chr1_-_94586651	0.076	ENST00000535735.1 ENST00000370225.3	ABCA4	ATP-binding cassette, sub-family A (ABC1), member 4
chr13_+_53602894	0.075	ENST00000219022.2	OLFM4	olfactomedin 4
chr1_-_95391315	0.075	ENST00000545882.1 ENST00000415017.1	CNN3	calponin 3, acidic
chr1_-_190446759	0.074	ENST00000367462.3	BRINP3	bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr15_+_58430567	0.073	ENST00000536493.1	AQP9	aquaporin 9
chr9_+_77230499	0.072	ENST00000396204.2	RORB	RAR-related orphan receptor B
chr5_-_141249154	0.072	ENST00000357517.5 ENST00000536585.1	PCDH1	protocadherin 1
chrX_-_64196376	0.072	ENST00000447788.2	ZC4H2	zinc finger, C4H2 domain containing
chr13_+_109248500	0.072	ENST00000356711.2	MYO16	myosin XVI
chr10_-_33623310	0.071	ENST00000395995.1 ENST00000374823.5 ENST00000374821.5 ENST00000374816.3	NRP1	neuropilin 1
chr6_-_33160231	0.071	ENST00000395194.1 ENST00000457788.1 ENST00000341947.2 ENST00000357486.1 ENST00000374714.1 ENST00000374713.1 ENST00000395197.1 ENST00000374712.1 ENST00000361917.1 ENST00000374708.4	COL11A2	collagen, type XI, alpha 2
chr6_+_151042224	0.070	ENST00000358517.2	PLEKHG1	pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chr2_-_99279928	0.070	ENST00000414521.2	MGAT4A	mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr14_-_37051798	0.070	ENST00000258829.5	NKX2-8	NK2 homeobox 8
chr7_+_107224364	0.069	ENST00000491150.1	BCAP29	B-cell receptor-associated protein 29
chrX_+_22050546	0.067	ENST00000379374.4	PHEX	phosphate regulating endopeptidase homolog, X-linked
chr10_-_116444371	0.066	ENST00000533213.2 ENST00000369252.4	ABLIM1	actin binding LIM protein 1
chr5_-_88119580	0.066	ENST00000539796.1	MEF2C	myocyte enhancer factor 2C
chr6_+_39760129	0.065	ENST00000274867.4	DAAM2	dishevelled associated activator of morphogenesis 2
chr3_-_33686743	0.065	ENST00000333778.6 ENST00000539981.1	CLASP2	cytoplasmic linker associated protein 2
chr1_-_204329013	0.064	ENST00000272203.3 ENST00000414478.1	PLEKHA6	pleckstrin homology domain containing, family A member 6
chr2_-_88285309	0.064	ENST00000420840.2	RGPD2	RANBP2-like and GRIP domain containing 2
chr12_+_20963632	0.062	ENST00000540853.1 ENST00000261196.2	SLCO1B3	solute carrier organic anion transporter family, member 1B3
chrX_-_64196307	0.062	ENST00000545618.1	ZC4H2	zinc finger, C4H2 domain containing
chr8_-_133637624	0.062	ENST00000522789.1	LRRC6	leucine rich repeat containing 6
chr7_-_87342564	0.061	ENST00000265724.3 ENST00000416177.1	ABCB1	ATP-binding cassette, sub-family B (MDR/TAP), member 1
chr9_-_124989804	0.060	ENST00000373755.2 ENST00000373754.2	LHX6	LIM homeobox 6
chr11_+_65554493	0.060	ENST00000335987.3	OVOL1	ovo-like zinc finger 1
chr8_+_24298531	0.059	ENST00000175238.6	ADAM7	ADAM metallopeptidase domain 7
chr3_+_46919235	0.058	ENST00000449590.1	PTH1R	parathyroid hormone 1 receptor
chr12_-_118796910	0.058	ENST00000541186.1 ENST00000539872.1	TAOK3	TAO kinase 3
chr8_-_72268889	0.057	ENST00000388742.4	EYA1	eyes absent homolog 1 (Drosophila)
chr20_+_60174827	0.056	ENST00000543233.1	CDH4	cadherin 4, type 1, R-cadherin (retinal)
chr8_-_17579726	0.056	ENST00000381861.3	MTUS1	microtubule associated tumor suppressor 1
chr1_+_214161272	0.056	ENST00000498508.2 ENST00000366958.4	PROX1	prospero homeobox 1
chr12_+_20963647	0.055	ENST00000381545.3	SLCO1B3	solute carrier organic anion transporter family, member 1B3
chr5_-_58295712	0.055	ENST00000317118.8	PDE4D	phosphodiesterase 4D, cAMP-specific
chr5_+_176811431	0.055	ENST00000512593.1 ENST00000324417.5	SLC34A1	solute carrier family 34 (type II sodium/phosphate contransporter), member 1
chr15_+_96869165	0.054	ENST00000421109.2	NR2F2	nuclear receptor subfamily 2, group F, member 2
chr5_-_134871639	0.054	ENST00000314744.4	NEUROG1	neurogenin 1
chrX_-_15288154	0.053	ENST00000380483.3 ENST00000380485.3 ENST00000380488.4	ASB9	ankyrin repeat and SOCS box containing 9
chrX_+_46771711	0.053	ENST00000424392.1 ENST00000397189.1	PHF16	jade family PHD finger 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	3.1	GO:0042693	muscle cell fate commitment(GO:0042693)
0.2	0.6	GO:0014889	muscle atrophy(GO:0014889) regulation of skeletal muscle tissue growth(GO:0048631)
0.2	1.0	GO:0008228	opsonization(GO:0008228)
0.1	0.4	GO:0019731	antibacterial humoral response(GO:0019731)
0.1	0.7	GO:0060999	positive regulation of dendritic spine development(GO:0060999)
0.1	0.5	GO:0021520	spinal cord motor neuron cell fate specification(GO:0021520)
0.1	0.7	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.1	1.1	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.1	1.5	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.1	0.2	GO:0035987	endodermal cell fate commitment(GO:0001711) endodermal cell differentiation(GO:0035987)
0.1	0.3	GO:0071392	cellular response to estradiol stimulus(GO:0071392)
0.0	0.2	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0	0.1	GO:1901419	regulation of response to alcohol(GO:1901419)
0.0	0.4	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.0	1.0	GO:0021846	cell proliferation in forebrain(GO:0021846)
0.0	0.1	GO:0055005	ventricular cardiac myofibril assembly(GO:0055005)
0.0	0.1	GO:0051451	myoblast migration(GO:0051451)
0.0	0.1	GO:2000644	low-density lipoprotein particle receptor catabolic process(GO:0032802) regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803) regulation of neurotrophin production(GO:0032899) negative regulation of neurotrophin production(GO:0032900) negative regulation of transforming growth factor beta production(GO:0071635) regulation of receptor catabolic process(GO:2000644)
0.0	0.4	GO:0031017	exocrine pancreas development(GO:0031017)
0.0	0.3	GO:0002726	positive regulation of T cell cytokine production(GO:0002726)
0.0	1.0	GO:0009954	proximal/distal pattern formation(GO:0009954)
0.0	0.2	GO:0002903	negative regulation of B cell apoptotic process(GO:0002903) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.0	0.1	GO:0046520	diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520)
0.0	0.2	GO:0035444	nickel cation transport(GO:0015675) vanadium ion transport(GO:0015676) ferrous iron transport(GO:0015684) lead ion transport(GO:0015692) nickel cation transmembrane transport(GO:0035444) ferrous iron import(GO:0070627) iron ion import(GO:0097286)
0.0	0.2	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.0	1.7	GO:0007585	respiratory gaseous exchange(GO:0007585)
0.0	0.6	GO:0034605	cellular response to heat(GO:0034605)
0.0	0.1	GO:0000239	pachytene(GO:0000239)
0.0	0.1	GO:0015670	carbon dioxide transport(GO:0015670)
0.0	0.1	GO:0060746	maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.0	0.0	GO:0070309	lens fiber cell morphogenesis(GO:0070309)
0.0	0.1	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0	0.1	GO:0015793	canalicular bile acid transport(GO:0015722) glycerol transport(GO:0015793) pyrimidine nucleobase transport(GO:0015855)
0.0	0.4	GO:0032008	positive regulation of TOR signaling(GO:0032008)
0.0	0.0	GO:0050955	thermoception(GO:0050955)
0.0	0.5	GO:0009812	flavonoid metabolic process(GO:0009812)
0.0	0.1	GO:0007525	somatic muscle development(GO:0007525)
0.0	0.1	GO:0008628	hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0	0.2	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.0	0.1	GO:0060023	soft palate development(GO:0060023)
0.0	0.3	GO:0015884	folic acid transport(GO:0015884)
0.0	0.2	GO:0021877	forebrain neuron fate commitment(GO:0021877)
0.0	0.1	GO:0060025	regulation of synaptic activity(GO:0060025)
0.0	0.0	GO:0009438	methylglyoxal metabolic process(GO:0009438)
0.0	0.0	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0	0.2	GO:0019228	neuronal action potential(GO:0019228)
0.0	0.1	GO:0009956	radial pattern formation(GO:0009956)
0.0	0.7	GO:0007368	determination of left/right symmetry(GO:0007368)
0.0	0.1	GO:2000172	regulation of branching morphogenesis of a nerve(GO:2000172)
0.0	0.0	GO:0072677	eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0	0.9	GO:0009408	response to heat(GO:0009408)
0.0	0.1	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0	0.0	GO:0060120	auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.0	0.3	GO:0031532	actin cytoskeleton reorganization(GO:0031532)
0.0	0.0	GO:0032825	regulation of natural killer cell differentiation(GO:0032823) positive regulation of natural killer cell differentiation(GO:0032825)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.1	GO:0005607	laminin-2 complex(GO:0005607)
0.2	1.2	GO:0033093	Weibel-Palade body(GO:0033093)
0.1	0.5	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1	1.1	GO:0032982	myosin filament(GO:0032982)
0.0	0.1	GO:0005726	perichromatin fibrils(GO:0005726)
0.0	0.1	GO:0036452	ESCRT III complex(GO:0000815) ESCRT complex(GO:0036452)
0.0	1.2	GO:0016010	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	0.4	GO:0042589	phagocytic vesicle membrane(GO:0030670) zymogen granule membrane(GO:0042589)
0.0	0.2	GO:0070826	paraferritin complex(GO:0070826)
0.0	0.3	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.6	GO:0042612	MHC class I protein complex(GO:0042612)
0.0	0.1	GO:0042584	chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0	0.3	GO:0070688	MLL5-L complex(GO:0070688)
0.0	1.2	GO:0031674	I band(GO:0031674)
0.0	0.3	GO:0042627	chylomicron(GO:0042627)
0.0	0.6	GO:0098636	integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0	0.1	GO:0042824	MHC class I peptide loading complex(GO:0042824)
0.0	0.2	GO:0033276	transcription factor TFTC complex(GO:0033276)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.7	GO:0097493	extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.1	0.6	GO:0030881	beta-2-microglobulin binding(GO:0030881)
0.1	3.9	GO:0070888	E-box binding(GO:0070888)
0.1	0.4	GO:0042043	neurexin family protein binding(GO:0042043)
0.1	0.5	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.1	1.0	GO:0030247	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1	0.5	GO:0047894	flavonol 3-sulfotransferase activity(GO:0047894)
0.1	0.3	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.1	1.2	GO:0019865	immunoglobulin binding(GO:0019865)
0.0	0.2	GO:0004346	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0	0.4	GO:0008179	adenylate cyclase binding(GO:0008179)
0.0	0.3	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0	0.4	GO:0051637	obsolete Gram-positive bacterial cell surface binding(GO:0051637)
0.0	0.2	GO:0015087	cobalt ion transmembrane transporter activity(GO:0015087) ferrous iron transmembrane transporter activity(GO:0015093) lead ion transmembrane transporter activity(GO:0015094) nickel cation transmembrane transporter activity(GO:0015099) vanadium ion transmembrane transporter activity(GO:0015100) chromium ion transmembrane transporter activity(GO:0070835)
0.0	0.1	GO:0044183	protein binding involved in protein folding(GO:0044183)
0.0	0.2	GO:0030021	extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0	0.1	GO:0050692	DBD domain binding(GO:0050692)
0.0	0.1	GO:0015254	glycerol channel activity(GO:0015254)
0.0	0.1	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0	0.1	GO:0030506	ankyrin binding(GO:0030506)
0.0	0.3	GO:0016986	obsolete transcription initiation factor activity(GO:0016986)
0.0	0.1	GO:0048406	nerve growth factor binding(GO:0048406)
0.0	0.8	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.1	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0	0.1	GO:0042910	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0	0.2	GO:0034185	apolipoprotein binding(GO:0034185)
0.0	0.4	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.3	GO:0005542	folic acid binding(GO:0005542)
0.0	1.1	GO:0046332	SMAD binding(GO:0046332)
0.0	0.2	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0	0.1	GO:0004991	parathyroid hormone receptor activity(GO:0004991)
0.0	1.0	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.2	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.3	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)