Motif ID: NR1D1
Z-value: 0.826
Transcription factors associated with NR1D1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
NR1D1 | ENSG00000126368.5 | NR1D1 |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 0.8 | GO:0003289 | septum primum development(GO:0003284) atrial septum primum morphogenesis(GO:0003289) |
0.2 | 0.9 | GO:0007262 | STAT protein import into nucleus(GO:0007262) |
0.2 | 0.6 | GO:0034139 | regulation of toll-like receptor 3 signaling pathway(GO:0034139) |
0.2 | 0.5 | GO:0060557 | positive regulation of chronic inflammatory response(GO:0002678) regulation of chronic inflammatory response to antigenic stimulus(GO:0002874) positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559) necroptotic process(GO:0070266) programmed necrotic cell death(GO:0097300) |
0.2 | 0.5 | GO:0019858 | cytosine metabolic process(GO:0019858) |
0.1 | 0.6 | GO:0009439 | cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440) |
0.1 | 0.3 | GO:0032223 | negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212) |
0.1 | 0.1 | GO:0032196 | transposition, DNA-mediated(GO:0006313) transposition(GO:0032196) |
0.1 | 0.7 | GO:0015074 | DNA integration(GO:0015074) |
0.1 | 0.8 | GO:0035590 | purinergic nucleotide receptor signaling pathway(GO:0035590) |
0.0 | 0.2 | GO:0033197 | response to vitamin E(GO:0033197) |
0.0 | 0.3 | GO:0005981 | regulation of glycogen catabolic process(GO:0005981) |
0.0 | 0.1 | GO:0045603 | positive regulation of endothelial cell differentiation(GO:0045603) |
0.0 | 0.1 | GO:0034122 | negative regulation of toll-like receptor signaling pathway(GO:0034122) |
0.0 | 0.2 | GO:0046642 | negative regulation of alpha-beta T cell proliferation(GO:0046642) |
0.0 | 0.3 | GO:0021978 | telencephalon regionalization(GO:0021978) |
0.0 | 0.3 | GO:0006108 | malate metabolic process(GO:0006108) NADH metabolic process(GO:0006734) |
0.0 | 0.2 | GO:0051085 | chaperone mediated protein folding requiring cofactor(GO:0051085) |
0.0 | 0.1 | GO:0045726 | negative regulation of macrophage cytokine production(GO:0010936) regulation of integrin biosynthetic process(GO:0045113) positive regulation of integrin biosynthetic process(GO:0045726) |
0.0 | 0.3 | GO:0046655 | folic acid metabolic process(GO:0046655) |
0.0 | 0.1 | GO:0015904 | tetracycline transport(GO:0015904) |
0.0 | 0.8 | GO:0046324 | regulation of glucose import(GO:0046324) |
0.0 | 0.1 | GO:0060528 | secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528) |
0.0 | 0.4 | GO:0007405 | neuroblast proliferation(GO:0007405) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 0.8 | GO:0000300 | obsolete peripheral to membrane of membrane fraction(GO:0000300) |
0.1 | 0.5 | GO:0001891 | phagocytic cup(GO:0001891) |
0.0 | 0.3 | GO:0042587 | glycogen granule(GO:0042587) |
0.0 | 0.9 | GO:0005796 | Golgi lumen(GO:0005796) |
0.0 | 0.3 | GO:0005922 | connexon complex(GO:0005922) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 0.7 | GO:0008907 | integrase activity(GO:0008907) |
0.1 | 0.6 | GO:0016784 | 3-mercaptopyruvate sulfurtransferase activity(GO:0016784) |
0.1 | 0.5 | GO:0004126 | cytidine deaminase activity(GO:0004126) |
0.1 | 0.9 | GO:0070053 | thrombospondin receptor activity(GO:0070053) |
0.1 | 0.3 | GO:0030060 | L-malate dehydrogenase activity(GO:0030060) |
0.1 | 0.8 | GO:0035381 | extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) |
0.1 | 0.3 | GO:0003990 | acetylcholinesterase activity(GO:0003990) |
0.1 | 0.3 | GO:0004489 | methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489) |
0.0 | 0.1 | GO:0047977 | hepoxilin-epoxide hydrolase activity(GO:0047977) |
0.0 | 0.2 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
0.0 | 0.7 | GO:0033613 | activating transcription factor binding(GO:0033613) |
0.0 | 0.3 | GO:0005243 | gap junction channel activity(GO:0005243) |
0.0 | 0.1 | GO:0015520 | tetracycline:proton antiporter activity(GO:0015520) |
0.0 | 0.3 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
0.0 | 0.5 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
0.0 | 0.3 | GO:0016493 | C-C chemokine receptor activity(GO:0016493) |
0.0 | 0.1 | GO:0004803 | transposase activity(GO:0004803) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 0.9 | ST_GA12_PATHWAY | G alpha 12 Pathway |
0.0 | 0.6 | SA_MMP_CYTOKINE_CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |