Motif ID: NR1I3

Z-value: 0.612


Transcription factors associated with NR1I3:

Gene SymbolEntrez IDGene Name
NR1I3 ENSG00000143257.7 NR1I3



Activity profile for motif NR1I3.

activity profile for motif NR1I3


Sorted Z-values histogram for motif NR1I3

Sorted Z-values for motif NR1I3



Network of associatons between targets according to the STRING database.



First level regulatory network of NR1I3

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_153330322 0.675 ENST00000368738.3
 S100A9
S100 calcium binding protein A9
chr2_-_209118974 0.674 ENST00000415913.1
ENST00000415282.1
ENST00000446179.1
 IDH1


isocitrate dehydrogenase 1 (NADP+), soluble


chr6_+_36097992 0.652 ENST00000211287.4
 MAPK13
mitogen-activated protein kinase 13
chr17_-_26694979 0.482 ENST00000438614.1
 VTN
vitronectin
chr17_-_26695013 0.471 ENST00000555059.2
 CTB-96E2.2
Homeobox protein SEBOX
chr15_+_96876340 0.457 ENST00000453270.2
 NR2F2
nuclear receptor subfamily 2, group F, member 2
chr10_-_73848764 0.380 ENST00000317376.4
ENST00000412663.1
 SPOCK2

sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2

chr1_-_205290865 0.369 ENST00000367157.3
 NUAK2
NUAK family, SNF1-like kinase, 2
chr18_-_19283649 0.363 ENST00000584464.1
ENST00000578270.1
 ABHD3

abhydrolase domain containing 3

chr18_-_19284724 0.357 ENST00000580981.1
ENST00000289119.2
 ABHD3

abhydrolase domain containing 3

chr16_-_16317321 0.343 ENST00000205557.7
ENST00000575728.1
 ABCC6

ATP-binding cassette, sub-family C (CFTR/MRP), member 6

chr17_-_53499310 0.323 ENST00000262065.3
 MMD
monocyte to macrophage differentiation-associated
chr17_+_32582293 0.309 ENST00000580907.1
ENST00000225831.4
 CCL2

chemokine (C-C motif) ligand 2

chr4_-_57524061 0.295 ENST00000508121.1
 HOPX
HOP homeobox
chr1_+_44401479 0.279 ENST00000438616.3
 ARTN
artemin
chr15_+_96875657 0.269 ENST00000559679.1
ENST00000394171.2
 NR2F2

nuclear receptor subfamily 2, group F, member 2

chr15_+_85523671 0.253 ENST00000310298.4
ENST00000557957.1
 PDE8A

phosphodiesterase 8A

chrX_+_128872998 0.252 ENST00000371106.3
 XPNPEP2
X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
chr11_-_82611448 0.236 ENST00000393399.2
ENST00000313010.3
 PRCP

prolylcarboxypeptidase (angiotensinase C)

chr15_+_43985084 0.230 ENST00000434505.1
ENST00000411750.1
 CKMT1A

creatine kinase, mitochondrial 1A

chr15_+_43885252 0.212 ENST00000453782.1
ENST00000300283.6
ENST00000437924.1
ENST00000450086.2
 CKMT1B



creatine kinase, mitochondrial 1B



chr7_+_100770328 0.207 ENST00000223095.4
ENST00000445463.2
 SERPINE1

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

chr20_+_62339381 0.193 ENST00000355969.6
ENST00000357119.4
ENST00000431125.1
ENST00000369967.3
ENST00000328969.5
 ZGPAT




zinc finger, CCCH-type with G patch domain




chr11_-_104480019 0.190 ENST00000536529.1
ENST00000545630.1
ENST00000538641.1
 RP11-886D15.1


RP11-886D15.1


chr19_-_48894104 0.181 ENST00000597017.1
 KDELR1
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
chr7_-_31380502 0.151 ENST00000297142.3
 NEUROD6
neuronal differentiation 6
chr16_-_75018968 0.149 ENST00000262144.6
 WDR59
WD repeat domain 59
chr2_-_86790593 0.143 ENST00000263856.4
ENST00000409225.2
 CHMP3

charged multivesicular body protein 3

chr1_+_15250596 0.133 ENST00000361144.5
 KAZN
kazrin, periplakin interacting protein
chr13_-_95131923 0.132 ENST00000377028.5
ENST00000446125.1
 DCT

dopachrome tautomerase

chr12_+_53693812 0.127 ENST00000549488.1
 C12orf10
chromosome 12 open reading frame 10
chr1_+_154377669 0.118 ENST00000368485.3
ENST00000344086.4
 IL6R

interleukin 6 receptor

chr6_+_108487245 0.108 ENST00000368986.4
 NR2E1
nuclear receptor subfamily 2, group E, member 1
chrX_-_110655391 0.106 ENST00000356915.2
ENST00000356220.3
 DCX

doublecortin

chr20_-_44007014 0.105 ENST00000372726.3
ENST00000537995.1
 TP53TG5

TP53 target 5

chr19_-_46296011 0.105 ENST00000377735.3
ENST00000270223.6
 DMWD

dystrophia myotonica, WD repeat containing

chr9_+_34179003 0.101 ENST00000545103.1
ENST00000543944.1
ENST00000536252.1
ENST00000540348.1
ENST00000297661.4
ENST00000379186.4
 UBAP1





ubiquitin associated protein 1





chr1_+_57320437 0.099 ENST00000361249.3
 C8A
complement component 8, alpha polypeptide
chr20_-_45142154 0.096 ENST00000347606.4
ENST00000457685.2
 ZNF334

zinc finger protein 334

chr19_+_2977444 0.093 ENST00000246112.4
ENST00000453329.1
ENST00000482627.1
ENST00000452088.1
 TLE6



transducin-like enhancer of split 6 (E(sp1) homolog, Drosophila)



chr17_-_3301704 0.091 ENST00000322608.2
 OR1E1
olfactory receptor, family 1, subfamily E, member 1
chr19_-_49140692 0.089 ENST00000222122.5
 DBP
D site of albumin promoter (albumin D-box) binding protein
chr17_-_34270668 0.077 ENST00000293274.4
 LYZL6
lysozyme-like 6
chr3_+_122103014 0.073 ENST00000232125.5
ENST00000477892.1
ENST00000469967.1
 FAM162A


family with sequence similarity 162, member A


chr17_-_34270697 0.071 ENST00000585556.1
 LYZL6
lysozyme-like 6
chrX_+_69674943 0.070 ENST00000542398.1
 DLG3
discs, large homolog 3 (Drosophila)
chr11_-_59950519 0.069 ENST00000528851.1
 MS4A6A
membrane-spanning 4-domains, subfamily A, member 6A
chr16_+_30710462 0.065 ENST00000262518.4
ENST00000395059.2
ENST00000344771.4
 SRCAP


Snf2-related CREBBP activator protein


chr1_+_26036093 0.063 ENST00000374329.1
 MAN1C1
mannosidase, alpha, class 1C, member 1
chr4_-_170897045 0.061 ENST00000508313.1
 RP11-205M3.3
RP11-205M3.3
chr19_-_51336443 0.054 ENST00000598673.1
 KLK15
kallikrein-related peptidase 15
chr19_-_49140609 0.051 ENST00000601104.1
 DBP
D site of albumin promoter (albumin D-box) binding protein
chr19_-_6604094 0.047 ENST00000597430.2
 CD70
CD70 molecule
chr17_-_62502399 0.046 ENST00000450599.2
ENST00000585060.1
 DDX5

DEAD (Asp-Glu-Ala-Asp) box helicase 5

chr1_+_145516560 0.041 ENST00000537888.1
 PEX11B
peroxisomal biogenesis factor 11 beta
chr2_-_69098566 0.041 ENST00000295379.1
 BMP10
bone morphogenetic protein 10
chr9_-_80646374 0.041 ENST00000286548.4
 GNAQ
guanine nucleotide binding protein (G protein), q polypeptide
chr17_-_62502639 0.038 ENST00000225792.5
ENST00000581697.1
ENST00000584279.1
ENST00000577922.1
 DDX5



DEAD (Asp-Glu-Ala-Asp) box helicase 5



chr1_+_43803475 0.035 ENST00000372470.3
ENST00000413998.2
 MPL

myeloproliferative leukemia virus oncogene

chr14_+_22748980 0.032 ENST00000390465.2
 TRAV38-2DV8
T cell receptor alpha variable 38-2/delta variable 8
chr1_+_145516252 0.027 ENST00000369306.3
 PEX11B
peroxisomal biogenesis factor 11 beta
chr1_-_151119087 0.025 ENST00000341697.3
ENST00000368914.3
 SEMA6C

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C

chr6_-_34113856 0.022 ENST00000538487.2
 GRM4
glutamate receptor, metabotropic 4
chr3_-_50396978 0.017 ENST00000266025.3
 TMEM115
transmembrane protein 115
chr6_-_31509714 0.014 ENST00000456662.1
ENST00000431908.1
ENST00000456976.1
ENST00000428450.1
ENST00000453105.2
ENST00000418897.1
ENST00000415382.2
ENST00000449074.2
ENST00000419020.1
ENST00000428098.1
 DDX39B









DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B









chr3_-_116164306 0.014 ENST00000490035.2
 LSAMP
limbic system-associated membrane protein
chr16_+_577697 0.014 ENST00000562370.1
ENST00000568988.1
ENST00000219611.2
 CAPN15


calpain 15


chr3_-_58419537 0.011 ENST00000474765.1
ENST00000485460.1
ENST00000302746.6
ENST00000383714.4
 PDHB



pyruvate dehydrogenase (lipoamide) beta



chr1_-_32210275 0.009 ENST00000440175.2
 BAI2
brain-specific angiogenesis inhibitor 2
chr1_-_225616515 0.007 ENST00000338179.2
ENST00000425080.1
 LBR

lamin B receptor

chr14_-_77787198 0.002 ENST00000261534.4
 POMT2
protein-O-mannosyltransferase 2
chr11_+_63137251 0.001 ENST00000310969.4
ENST00000279178.3
 SLC22A9

solute carrier family 22 (organic anion transporter), member 9

chr6_+_96969672 0.000 ENST00000369278.4
 UFL1
UFM1-specific ligase 1
chr9_-_91793675 0.000 ENST00000375835.4
ENST00000375830.1
 SHC3

SHC (Src homology 2 domain containing) transforming protein 3


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0006740 glyoxylate cycle(GO:0006097) NADPH regeneration(GO:0006740)
0.2 0.7 GO:0009956 radial pattern formation(GO:0009956)
0.2 0.7 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 0.2 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.4 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.3 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.3 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415) regulation of skeletal muscle tissue regeneration(GO:0043416)
0.0 0.1 GO:0002384 hepatic immune response(GO:0002384)
0.0 0.2 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.2 GO:0006621 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0 0.1 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.4 GO:0019835 cytolysis(GO:0019835)
0.0 0.2 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.0 GO:0014742 positive regulation of cardiac muscle hypertrophy(GO:0010613) positive regulation of muscle hypertrophy(GO:0014742)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.7 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.1 0.3 GO:0000156 phosphorelay response regulator activity(GO:0000156)
0.1 0.3 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 0.7 GO:0003706 obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0 0.2 GO:0005046 KDEL sequence binding(GO:0005046)
0.0 0.2 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.5 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.1 GO:0019981 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.0 0.1 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.7 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.2 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.1 GO:0004167 dopachrome isomerase activity(GO:0004167)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 SIG_CD40PATHWAYMAP Genes related to CD40 signaling