Motif ID: NR2F1
Z-value: 0.639
Transcription factors associated with NR2F1:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| NR2F1 | ENSG00000175745.7 | NR2F1 |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 0.5 | GO:0090598 | male genitalia morphogenesis(GO:0048808) lateral sprouting involved in mammary gland duct morphogenesis(GO:0060599) male anatomical structure morphogenesis(GO:0090598) |
| 0.1 | 0.6 | GO:0035444 | nickel cation transport(GO:0015675) vanadium ion transport(GO:0015676) ferrous iron transport(GO:0015684) lead ion transport(GO:0015692) nickel cation transmembrane transport(GO:0035444) ferrous iron import(GO:0070627) iron ion import(GO:0097286) |
| 0.1 | 0.4 | GO:0042262 | DNA protection(GO:0042262) |
| 0.1 | 0.3 | GO:0006348 | chromatin silencing at telomere(GO:0006348) |
| 0.1 | 0.5 | GO:0060346 | bone trabecula formation(GO:0060346) bone trabecula morphogenesis(GO:0061430) |
| 0.1 | 0.6 | GO:0060666 | dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666) |
| 0.1 | 0.2 | GO:1902414 | protein localization to adherens junction(GO:0071896) protein localization to cell junction(GO:1902414) |
| 0.1 | 0.3 | GO:0033539 | fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539) |
| 0.0 | 0.2 | GO:0050668 | positive regulation of sulfur amino acid metabolic process(GO:0031337) positive regulation of cellular amino acid metabolic process(GO:0045764) negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963) positive regulation of homocysteine metabolic process(GO:0050668) |
| 0.0 | 0.1 | GO:0014063 | regulation of serotonin secretion(GO:0014062) negative regulation of serotonin secretion(GO:0014063) |
| 0.0 | 0.3 | GO:0015671 | oxygen transport(GO:0015671) |
| 0.0 | 2.1 | GO:0006636 | unsaturated fatty acid biosynthetic process(GO:0006636) |
| 0.0 | 0.3 | GO:0040037 | negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037) |
| 0.0 | 0.4 | GO:0001522 | pseudouridine synthesis(GO:0001522) |
| 0.0 | 0.3 | GO:0036336 | dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336) |
| 0.0 | 0.4 | GO:0002347 | response to tumor cell(GO:0002347) |
| 0.0 | 0.1 | GO:0048003 | antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) |
| 0.0 | 0.3 | GO:0016540 | protein autoprocessing(GO:0016540) |
| 0.0 | 0.1 | GO:0034382 | chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830) |
| 0.0 | 0.1 | GO:0071318 | cellular response to ATP(GO:0071318) |
| 0.0 | 0.8 | GO:0043462 | regulation of ATPase activity(GO:0043462) |
| 0.0 | 0.3 | GO:0097031 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
| 0.0 | 0.1 | GO:0048170 | positive regulation of long-term neuronal synaptic plasticity(GO:0048170) long-term synaptic potentiation(GO:0060291) |
| 0.0 | 0.1 | GO:0046485 | ether lipid metabolic process(GO:0046485) |
| 0.0 | 0.1 | GO:0015811 | sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811) |
| 0.0 | 0.1 | GO:0060406 | positive regulation of penile erection(GO:0060406) |
| 0.0 | 1.0 | GO:1900181 | negative regulation of protein import into nucleus(GO:0042308) negative regulation of protein localization to nucleus(GO:1900181) negative regulation of protein import(GO:1904590) |
| 0.0 | 0.3 | GO:0048268 | negative regulation of receptor-mediated endocytosis(GO:0048261) clathrin coat assembly(GO:0048268) |
| 0.0 | 0.1 | GO:0034337 | RNA folding(GO:0034337) DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029) regulation of DNA methylation(GO:0044030) |
| 0.0 | 0.1 | GO:0010966 | regulation of phosphate transport(GO:0010966) |
| 0.0 | 0.1 | GO:0015889 | cobalamin transport(GO:0015889) |
| 0.0 | 0.4 | GO:0007628 | adult walking behavior(GO:0007628) walking behavior(GO:0090659) |
| 0.0 | 0.1 | GO:0090343 | positive regulation of cell aging(GO:0090343) |
| 0.0 | 0.1 | GO:0034310 | primary alcohol catabolic process(GO:0034310) |
| 0.0 | 0.1 | GO:0045039 | protein import into mitochondrial inner membrane(GO:0045039) |
| 0.0 | 0.3 | GO:0006525 | arginine metabolic process(GO:0006525) |
| 0.0 | 0.2 | GO:0043171 | peptide catabolic process(GO:0043171) |
| 0.0 | 0.3 | GO:0048024 | regulation of mRNA splicing, via spliceosome(GO:0048024) |
| 0.0 | 0.1 | GO:0006654 | phosphatidic acid biosynthetic process(GO:0006654) |
| 0.0 | 0.3 | GO:0032387 | negative regulation of intracellular transport(GO:0032387) |
| 0.0 | 0.1 | GO:0033137 | negative regulation of peptidyl-serine phosphorylation(GO:0033137) |
| 0.0 | 0.1 | GO:0007525 | somatic muscle development(GO:0007525) |
| 0.0 | 0.1 | GO:0006474 | N-terminal protein amino acid acetylation(GO:0006474) |
| 0.0 | 0.0 | GO:0071218 | cellular response to misfolded protein(GO:0071218) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.6 | GO:0070826 | paraferritin complex(GO:0070826) |
| 0.1 | 0.3 | GO:0031838 | haptoglobin-hemoglobin complex(GO:0031838) |
| 0.1 | 0.3 | GO:0031305 | integral component of mitochondrial inner membrane(GO:0031305) |
| 0.0 | 0.3 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) |
| 0.0 | 0.8 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
| 0.0 | 0.4 | GO:0032040 | small-subunit processome(GO:0032040) |
| 0.0 | 0.2 | GO:0034750 | Scrib-APC-beta-catenin complex(GO:0034750) |
| 0.0 | 0.5 | GO:0001527 | microfibril(GO:0001527) |
| 0.0 | 0.3 | GO:0005677 | chromatin silencing complex(GO:0005677) |
| 0.0 | 0.6 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.0 | 0.3 | GO:0033180 | proton-transporting V-type ATPase, V1 domain(GO:0033180) |
| 0.0 | 0.1 | GO:0005954 | calcium- and calmodulin-dependent protein kinase complex(GO:0005954) |
| 0.0 | 0.1 | GO:0031232 | extrinsic component of external side of plasma membrane(GO:0031232) |
| 0.0 | 0.3 | GO:0030122 | AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128) |
| 0.0 | 0.1 | GO:0042719 | mitochondrial intermembrane space protein transporter complex(GO:0042719) |
| 0.0 | 0.4 | GO:0016592 | mediator complex(GO:0016592) |
| 0.0 | 0.2 | GO:0045335 | phagocytic vesicle(GO:0045335) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 1.9 | GO:0016717 | oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717) |
| 0.1 | 0.4 | GO:0004730 | pseudouridylate synthase activity(GO:0004730) |
| 0.1 | 0.4 | GO:0030611 | arsenate reductase activity(GO:0030611) |
| 0.1 | 0.6 | GO:0015087 | cobalt ion transmembrane transporter activity(GO:0015087) ferrous iron transmembrane transporter activity(GO:0015093) lead ion transmembrane transporter activity(GO:0015094) nickel cation transmembrane transporter activity(GO:0015099) vanadium ion transmembrane transporter activity(GO:0015100) chromium ion transmembrane transporter activity(GO:0070835) |
| 0.1 | 0.5 | GO:0004882 | androgen receptor activity(GO:0004882) |
| 0.1 | 0.4 | GO:0047184 | 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184) |
| 0.1 | 0.3 | GO:0048039 | ubiquinone binding(GO:0048039) |
| 0.1 | 0.3 | GO:0032050 | clathrin heavy chain binding(GO:0032050) |
| 0.1 | 0.6 | GO:0046870 | cadmium ion binding(GO:0046870) |
| 0.1 | 0.3 | GO:0042903 | tubulin deacetylase activity(GO:0042903) |
| 0.1 | 0.8 | GO:0004862 | cAMP-dependent protein kinase inhibitor activity(GO:0004862) |
| 0.1 | 0.6 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
| 0.0 | 0.2 | GO:0003956 | NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956) |
| 0.0 | 0.2 | GO:0004667 | prostaglandin-D synthase activity(GO:0004667) |
| 0.0 | 0.1 | GO:0045030 | A1 adenosine receptor binding(GO:0031686) UTP-activated nucleotide receptor activity(GO:0045030) |
| 0.0 | 0.1 | GO:0017077 | oxidative phosphorylation uncoupler activity(GO:0017077) |
| 0.0 | 0.1 | GO:0004723 | calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) |
| 0.0 | 0.2 | GO:0016206 | catechol O-methyltransferase activity(GO:0016206) |
| 0.0 | 0.3 | GO:0015288 | porin activity(GO:0015288) |
| 0.0 | 0.1 | GO:0034594 | phosphatidylinositol trisphosphate phosphatase activity(GO:0034594) |
| 0.0 | 0.1 | GO:0008131 | primary amine oxidase activity(GO:0008131) |
| 0.0 | 0.4 | GO:0005003 | ephrin receptor activity(GO:0005003) |
| 0.0 | 0.2 | GO:0004499 | N,N-dimethylaniline monooxygenase activity(GO:0004499) |
| 0.0 | 0.1 | GO:0005105 | type 1 fibroblast growth factor receptor binding(GO:0005105) |
| 0.0 | 0.1 | GO:0016714 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714) |
| 0.0 | 0.1 | GO:0015174 | basic amino acid transmembrane transporter activity(GO:0015174) L-cystine transmembrane transporter activity(GO:0015184) |
| 0.0 | 0.3 | GO:0005344 | oxygen transporter activity(GO:0005344) |
| 0.0 | 0.3 | GO:0004065 | arylsulfatase activity(GO:0004065) |
| 0.0 | 0.7 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
| 0.0 | 0.1 | GO:0030881 | beta-2-microglobulin binding(GO:0030881) |
| 0.0 | 0.1 | GO:0034875 | oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875) |
| 0.0 | 0.1 | GO:0030492 | hemoglobin binding(GO:0030492) |
| 0.0 | 0.1 | GO:0001609 | G-protein coupled adenosine receptor activity(GO:0001609) |
| 0.0 | 0.3 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.0 | 0.4 | GO:0001104 | RNA polymerase II transcription cofactor activity(GO:0001104) |
| 0.0 | 0.2 | GO:0052866 | phosphatidylinositol phosphate phosphatase activity(GO:0052866) |
| 0.0 | 0.2 | GO:0003840 | gamma-glutamyltransferase activity(GO:0003840) |
| 0.0 | 0.1 | GO:0016623 | oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623) |
| 0.0 | 0.3 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
| 0.0 | 0.0 | GO:0070643 | vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643) |
| 0.0 | 0.3 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.0 | 1.1 | GO:0008307 | structural constituent of muscle(GO:0008307) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.4 | ST_IL_13_PATHWAY | Interleukin 13 (IL-13) Pathway |
