Motif ID: NR3C1

Z-value: 2.099


Transcription factors associated with NR3C1:

Gene SymbolEntrez IDGene Name
NR3C1 ENSG00000113580.10 NR3C1



Activity profile for motif NR3C1.

activity profile for motif NR3C1


Sorted Z-values histogram for motif NR3C1

Sorted Z-values for motif NR3C1



Network of associatons between targets according to the STRING database.



First level regulatory network of NR3C1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_-_106054659 7.270 ENST00000390539.2
IGHA2
immunoglobulin heavy constant alpha 2 (A2m marker)
chr14_-_106692191 7.072 ENST00000390607.2
IGHV3-21
immunoglobulin heavy variable 3-21
chr22_+_23237555 5.851 ENST00000390321.2
IGLC1
immunoglobulin lambda constant 1 (Mcg marker)
chr22_+_23248512 5.486 ENST00000390325.2
IGLC3
immunoglobulin lambda constant 3 (Kern-Oz+ marker)
chr22_+_23243156 4.878 ENST00000390323.2
IGLC2
immunoglobulin lambda constant 2 (Kern-Oz- marker)
chr16_+_32077386 4.793 ENST00000354689.6
IGHV3OR16-9
immunoglobulin heavy variable 3/OR16-9 (non-functional)
chr14_-_106174960 4.673 ENST00000390547.2
IGHA1
immunoglobulin heavy constant alpha 1
chr22_+_23241661 3.666 ENST00000390322.2
IGLJ2
immunoglobulin lambda joining 2
chr6_-_33048483 3.439 ENST00000419277.1
HLA-DPA1
major histocompatibility complex, class II, DP alpha 1
chr6_+_33048222 3.421 ENST00000428835.1
HLA-DPB1
major histocompatibility complex, class II, DP beta 1
chr5_-_149792295 3.031 ENST00000518797.1
ENST00000524315.1
ENST00000009530.7
ENST00000377795.3
CD74



CD74 molecule, major histocompatibility complex, class II invariant chain



chr14_-_106994333 2.728 ENST00000390624.2
IGHV3-48
immunoglobulin heavy variable 3-48
chr15_-_22448819 2.586 ENST00000604066.1
IGHV1OR15-1
immunoglobulin heavy variable 1/OR15-1 (non-functional)
chr22_+_23264766 2.576 ENST00000390331.2
IGLC7
immunoglobulin lambda constant 7
chr14_-_106518922 2.472 ENST00000390598.2
IGHV3-7
immunoglobulin heavy variable 3-7
chr14_-_106642049 2.399 ENST00000390605.2
IGHV1-18
immunoglobulin heavy variable 1-18
chr1_+_158900568 2.380 ENST00000458222.1
PYHIN1
pyrin and HIN domain family, member 1
chr3_-_119278446 2.286 ENST00000264246.3
CD80
CD80 molecule
chr4_+_15779901 2.177 ENST00000226279.3
CD38
CD38 molecule
chr19_+_4229495 2.099 ENST00000221847.5
EBI3
Epstein-Barr virus induced 3
chr2_-_158300556 2.097 ENST00000264192.3
CYTIP
cytohesin 1 interacting protein
chr22_+_23040274 2.016 ENST00000390306.2
IGLV2-23
immunoglobulin lambda variable 2-23
chr14_-_107219365 1.995 ENST00000424969.2
IGHV3-74
immunoglobulin heavy variable 3-74
chr14_-_106330458 1.988 ENST00000461719.1
IGHJ4
immunoglobulin heavy joining 4
chr15_+_31658349 1.914 ENST00000558844.1
KLF13
Kruppel-like factor 13
chr6_+_32605195 1.881 ENST00000374949.2
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chr1_-_207095324 1.872 ENST00000530505.1
ENST00000367091.3
ENST00000442471.2
FAIM3


Fas apoptotic inhibitory molecule 3


chr15_-_20193370 1.834 ENST00000558565.2
IGHV3OR15-7
immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr1_+_158969752 1.786 ENST00000566111.1
IFI16
interferon, gamma-inducible protein 16
chr8_+_54793454 1.725 ENST00000276500.4
RGS20
regulator of G-protein signaling 20
chr14_-_106573756 1.705 ENST00000390601.2
IGHV3-11
immunoglobulin heavy variable 3-11 (gene/pseudogene)
chr8_+_54793425 1.693 ENST00000522225.1
RGS20
regulator of G-protein signaling 20
chr6_+_29795595 1.634 ENST00000360323.6
ENST00000376818.3
ENST00000376815.3
HLA-G


major histocompatibility complex, class I, G


chr5_+_49961727 1.625 ENST00000505697.2
ENST00000503750.2
ENST00000514342.2
PARP8


poly (ADP-ribose) polymerase family, member 8


chr6_+_32811885 1.594 ENST00000458296.1
ENST00000413039.1
ENST00000429600.1
ENST00000412095.1
ENST00000415067.1
ENST00000395330.1
TAPSAR1




PSMB9
TAP1 and PSMB8 antisense RNA 1




proteasome (prosome, macropain) subunit, beta type, 9
chr3_-_127541679 1.565 ENST00000265052.5
MGLL
monoglyceride lipase
chr14_-_106668095 1.558 ENST00000390606.2
IGHV3-20
immunoglobulin heavy variable 3-20
chr2_-_191878162 1.553 ENST00000540176.1
STAT1
signal transducer and activator of transcription 1, 91kDa
chr6_+_6588902 1.518 ENST00000230568.4
LY86
lymphocyte antigen 86
chr3_+_122044084 1.511 ENST00000264474.3
ENST00000479204.1
CSTA

cystatin A (stefin A)

chr14_-_106552755 1.501 ENST00000390600.2
IGHV3-9
immunoglobulin heavy variable 3-9
chr14_-_106845789 1.455 ENST00000390617.2
IGHV3-35
immunoglobulin heavy variable 3-35 (non-functional)
chr11_+_121447469 1.450 ENST00000532694.1
ENST00000534286.1
SORL1

sortilin-related receptor, L(DLR class) A repeats containing

chr6_+_32605134 1.446 ENST00000343139.5
ENST00000395363.1
ENST00000496318.1
HLA-DQA1


major histocompatibility complex, class II, DQ alpha 1


chr6_-_90121938 1.432 ENST00000369415.4
RRAGD
Ras-related GTP binding D
chr14_-_106471723 1.424 ENST00000390595.2
IGHV1-3
immunoglobulin heavy variable 1-3
chr14_-_106866934 1.413 ENST00000390618.2
IGHV3-38
immunoglobulin heavy variable 3-38 (non-functional)
chr6_-_31324943 1.402 ENST00000412585.2
ENST00000434333.1
HLA-B

major histocompatibility complex, class I, B

chr1_-_207095212 1.386 ENST00000420007.2
FAIM3
Fas apoptotic inhibitory molecule 3
chr14_-_106453155 1.382 ENST00000390594.2
IGHV1-2
immunoglobulin heavy variable 1-2
chr14_-_106926724 1.381 ENST00000434710.1
IGHV3-43
immunoglobulin heavy variable 3-43
chr16_+_12058961 1.358 ENST00000053243.1
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr16_-_33647696 1.343 ENST00000558425.1
ENST00000569103.2
RP11-812E19.9

Uncharacterized protein

chr9_-_6645628 1.329 ENST00000321612.6
GLDC
glycine dehydrogenase (decarboxylating)
chr3_-_127541194 1.320 ENST00000453507.2
MGLL
monoglyceride lipase
chr8_+_11351876 1.316 ENST00000529894.1
BLK
B lymphoid tyrosine kinase
chr6_-_32811771 1.286 ENST00000395339.3
ENST00000374882.3
PSMB8

proteasome (prosome, macropain) subunit, beta type, 8

chr14_-_107049312 1.263 ENST00000390627.2
IGHV3-53
immunoglobulin heavy variable 3-53
chr16_+_33020496 1.260 ENST00000565407.2
IGHV3OR16-8
immunoglobulin heavy variable 3/OR16-8 (non-functional)
chr14_-_106725723 1.259 ENST00000390609.2
IGHV3-23
immunoglobulin heavy variable 3-23
chr11_+_5710919 1.250 ENST00000379965.3
ENST00000425490.1
TRIM22

tripartite motif containing 22

chr19_+_42381173 1.235 ENST00000221972.3
CD79A
CD79a molecule, immunoglobulin-associated alpha
chr8_-_70745575 1.224 ENST00000524945.1
SLCO5A1
solute carrier organic anion transporter family, member 5A1
chr6_+_32821924 1.214 ENST00000374859.2
ENST00000453265.2
PSMB9

proteasome (prosome, macropain) subunit, beta type, 9

chr12_-_15114492 1.210 ENST00000541546.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr11_+_7626950 1.205 ENST00000530181.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr20_+_46130619 1.195 ENST00000372004.3
NCOA3
nuclear receptor coactivator 3
chr15_-_79237433 1.135 ENST00000220166.5
CTSH
cathepsin H
chr3_+_98250743 1.132 ENST00000284311.3
GPR15
G protein-coupled receptor 15
chr1_-_9129598 1.126 ENST00000535586.1
SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr6_-_133079022 1.122 ENST00000525289.1
ENST00000326499.6
VNN2

vanin 2

chr22_+_22764088 1.107 ENST00000390299.2
IGLV1-40
immunoglobulin lambda variable 1-40
chr7_-_30029574 1.102 ENST00000426154.1
ENST00000421434.1
ENST00000434476.2
SCRN1


secernin 1


chr7_-_94285511 1.084 ENST00000265735.7
SGCE
sarcoglycan, epsilon
chr22_+_22712087 1.073 ENST00000390294.2
IGLV1-47
immunoglobulin lambda variable 1-47
chr19_-_2041159 1.073 ENST00000589441.1
MKNK2
MAP kinase interacting serine/threonine kinase 2
chr3_-_119278376 1.070 ENST00000478182.1
CD80
CD80 molecule
chr19_+_57874835 1.024 ENST00000282282.3
ENST00000543226.1
ENST00000596755.1
ENST00000597658.1
ZNF547
TRAPPC2P1

AC003002.4
zinc finger protein 547
trafficking protein particle complex 2 pseudogene 1

Uncharacterized protein
chr7_-_134143841 1.021 ENST00000285930.4
AKR1B1
aldo-keto reductase family 1, member B1 (aldose reductase)
chr1_-_27998689 1.018 ENST00000339145.4
ENST00000362020.4
ENST00000361157.6
IFI6


interferon, alpha-inducible protein 6


chr5_+_67588391 1.006 ENST00000523872.1
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr7_-_94285402 0.968 ENST00000428696.2
ENST00000445866.2
SGCE

sarcoglycan, epsilon

chr9_-_37034028 0.967 ENST00000520281.1
ENST00000446742.1
ENST00000522003.1
ENST00000523145.1
ENST00000414447.1
ENST00000377847.2
ENST00000377853.2
ENST00000377852.2
ENST00000523241.1
ENST00000520154.1
ENST00000358127.4
PAX5










paired box 5










chr4_+_37892682 0.936 ENST00000508802.1
ENST00000261439.4
ENST00000402522.1
TBC1D1


TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1


chr3_+_52245458 0.934 ENST00000459884.1
ALAS1
aminolevulinate, delta-, synthase 1
chr8_-_98290087 0.933 ENST00000322128.3
TSPYL5
TSPY-like 5
chr9_-_88356789 0.927 ENST00000357081.3
ENST00000376081.4
ENST00000337006.4
ENST00000376109.3
AGTPBP1



ATP/GTP binding protein 1



chr2_-_175499294 0.920 ENST00000392547.2
WIPF1
WAS/WASL interacting protein family, member 1
chr14_-_106733624 0.912 ENST00000390610.2
IGHV1-24
immunoglobulin heavy variable 1-24
chr2_-_136875712 0.908 ENST00000241393.3
CXCR4
chemokine (C-X-C motif) receptor 4
chr7_-_30029367 0.907 ENST00000242059.5
SCRN1
secernin 1
chr19_-_10445399 0.883 ENST00000592945.1
ICAM3
intercellular adhesion molecule 3
chr2_+_182321925 0.873 ENST00000339307.4
ENST00000397033.2
ITGA4

integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)

chr22_-_17680472 0.873 ENST00000330232.4
CECR1
cat eye syndrome chromosome region, candidate 1
chr12_-_92539614 0.855 ENST00000256015.3
BTG1
B-cell translocation gene 1, anti-proliferative
chr8_+_38614807 0.854 ENST00000330691.6
ENST00000348567.4
TACC1

transforming, acidic coiled-coil containing protein 1

chr16_+_4674787 0.854 ENST00000262370.7
MGRN1
mahogunin ring finger 1, E3 ubiquitin protein ligase
chr14_+_60715928 0.846 ENST00000395076.4
PPM1A
protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr9_+_126777676 0.840 ENST00000488674.2
LHX2
LIM homeobox 2
chr17_-_38020392 0.839 ENST00000346872.3
ENST00000439167.2
ENST00000377945.3
ENST00000394189.2
ENST00000377944.3
ENST00000377958.2
ENST00000535189.1
ENST00000377952.2
IKZF3







IKAROS family zinc finger 3 (Aiolos)







chr15_+_81475047 0.837 ENST00000559388.1
IL16
interleukin 16
chr15_+_25200108 0.829 ENST00000579070.1
ENST00000577565.1
ENST00000577949.1
ENST00000338094.6
ENST00000338327.4
SNRPN

SNURF


small nuclear ribonucleoprotein polypeptide N

SNRPN upstream reading frame protein


chr21_-_46340884 0.829 ENST00000302347.5
ENST00000517819.1
ITGB2

integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)

chr21_-_46340770 0.818 ENST00000397854.3
ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr3_+_179370517 0.811 ENST00000263966.3
USP13
ubiquitin specific peptidase 13 (isopeptidase T-3)
chr6_-_109777128 0.768 ENST00000358807.3
ENST00000358577.3
MICAL1

microtubule associated monooxygenase, calponin and LIM domain containing 1

chr6_-_32821599 0.757 ENST00000354258.4
TAP1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr22_+_22681656 0.752 ENST00000390291.2
IGLV1-50
immunoglobulin lambda variable 1-50 (non-functional)
chr8_+_26247878 0.751 ENST00000518611.1
BNIP3L
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr14_+_61654271 0.730 ENST00000555185.1
ENST00000557294.1
ENST00000556778.1
PRKCH


protein kinase C, eta


chr19_-_39108552 0.726 ENST00000591517.1
MAP4K1
mitogen-activated protein kinase kinase kinase kinase 1
chr2_-_89292422 0.723 ENST00000495489.1
IGKV1-8
immunoglobulin kappa variable 1-8
chr4_-_105416039 0.719 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr14_-_107114267 0.708 ENST00000454421.2
IGHV3-64
immunoglobulin heavy variable 3-64
chr3_-_121379739 0.703 ENST00000428394.2
ENST00000314583.3
HCLS1

hematopoietic cell-specific Lyn substrate 1

chr7_+_26332645 0.698 ENST00000396376.1
SNX10
sorting nexin 10
chr14_+_24641062 0.688 ENST00000311457.3
ENST00000557806.1
ENST00000559919.1
REC8


REC8 meiotic recombination protein


chr14_-_106816253 0.673 ENST00000390615.2
IGHV3-33
immunoglobulin heavy variable 3-33
chr8_-_103136481 0.672 ENST00000524209.1
ENST00000517822.1
ENST00000523923.1
ENST00000521599.1
ENST00000521964.1
ENST00000311028.3
ENST00000518166.1
NCALD






neurocalcin delta






chr6_-_27835357 0.612 ENST00000331442.3
HIST1H1B
histone cluster 1, H1b
chr22_+_37309662 0.605 ENST00000403662.3
ENST00000262825.5
CSF2RB

colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)

chr7_-_40174201 0.603 ENST00000306984.6
MPLKIP
M-phase specific PLK1 interacting protein
chr2_-_214016314 0.600 ENST00000434687.1
ENST00000374319.4
IKZF2

IKAROS family zinc finger 2 (Helios)

chr10_-_13523073 0.599 ENST00000440282.1
BEND7
BEN domain containing 7
chr2_+_233925064 0.598 ENST00000359570.5
ENST00000538935.1
INPP5D

inositol polyphosphate-5-phosphatase, 145kDa

chr3_-_58200398 0.598 ENST00000318316.3
ENST00000460422.1
ENST00000483681.1
DNASE1L3


deoxyribonuclease I-like 3


chr17_-_67138015 0.596 ENST00000284425.2
ENST00000590645.1
ABCA6

ATP-binding cassette, sub-family A (ABC1), member 6

chr10_-_135090338 0.594 ENST00000415217.3
ADAM8
ADAM metallopeptidase domain 8
chr16_+_4674814 0.593 ENST00000415496.1
ENST00000587747.1
ENST00000399577.5
ENST00000588994.1
ENST00000586183.1
MGRN1




mahogunin ring finger 1, E3 ubiquitin protein ligase




chr10_+_70847852 0.590 ENST00000242465.3
SRGN
serglycin
chr11_+_57365150 0.588 ENST00000457869.1
ENST00000340687.6
ENST00000378323.4
ENST00000378324.2
ENST00000403558.1
SERPING1




serpin peptidase inhibitor, clade G (C1 inhibitor), member 1




chr19_-_6670128 0.587 ENST00000245912.3
TNFSF14
tumor necrosis factor (ligand) superfamily, member 14
chr15_+_75080883 0.583 ENST00000567571.1
CSK
c-src tyrosine kinase
chr2_-_89340242 0.581 ENST00000480492.1
IGKV1-12
immunoglobulin kappa variable 1-12
chr16_+_33006369 0.570 ENST00000425181.3
IGHV3OR16-10
immunoglobulin heavy variable 3/OR16-10 (non-functional)
chr3_+_169490606 0.557 ENST00000349841.5
MYNN
myoneurin
chr11_+_32112431 0.554 ENST00000054950.3
RCN1
reticulocalbin 1, EF-hand calcium binding domain
chr7_-_26904317 0.543 ENST00000345317.2
SKAP2
src kinase associated phosphoprotein 2
chr11_+_117857063 0.533 ENST00000227752.3
ENST00000541785.1
ENST00000545409.1
IL10RA


interleukin 10 receptor, alpha


chr18_+_34124507 0.524 ENST00000591635.1
FHOD3
formin homology 2 domain containing 3
chr2_-_89513402 0.517 ENST00000498435.1
IGKV1-27
immunoglobulin kappa variable 1-27
chr22_-_37172111 0.517 ENST00000417951.2
ENST00000430701.1
ENST00000433985.2
IFT27


intraflagellar transport 27 homolog (Chlamydomonas)


chr2_+_102608306 0.504 ENST00000332549.3
IL1R2
interleukin 1 receptor, type II
chr20_-_62711259 0.502 ENST00000332298.5
RGS19
regulator of G-protein signaling 19
chr16_+_50730910 0.501 ENST00000300589.2
NOD2
nucleotide-binding oligomerization domain containing 2
chr6_-_137113604 0.498 ENST00000359015.4
MAP3K5
mitogen-activated protein kinase kinase kinase 5
chr22_-_37172191 0.498 ENST00000340630.5
IFT27
intraflagellar transport 27 homolog (Chlamydomonas)
chr9_-_21335240 0.497 ENST00000537938.1
KLHL9
kelch-like family member 9
chr16_+_84209539 0.497 ENST00000569735.1
DNAAF1
dynein, axonemal, assembly factor 1
chr6_-_39693111 0.495 ENST00000373215.3
ENST00000538893.1
ENST00000287152.7
ENST00000373216.3
KIF6



kinesin family member 6



chr17_-_34756219 0.492 ENST00000451448.2
ENST00000394359.3
TBC1D3C
TBC1D3H
TBC1 domain family, member 3C
TBC1 domain family, member 3H
chr3_-_69101413 0.490 ENST00000398559.2
TMF1
TATA element modulatory factor 1
chr16_+_32063311 0.489 ENST00000426099.1
AC142381.1
AC142381.1
chr10_-_135090360 0.485 ENST00000486609.1
ENST00000445355.3
ENST00000485491.2
ADAM8


ADAM metallopeptidase domain 8


chr18_+_13611763 0.484 ENST00000585931.1
LDLRAD4
low density lipoprotein receptor class A domain containing 4
chr15_+_74833518 0.480 ENST00000346246.5
ARID3B
AT rich interactive domain 3B (BRIGHT-like)
chr19_+_58281014 0.480 ENST00000391702.3
ENST00000598885.1
ENST00000598183.1
ENST00000396154.2
ENST00000599802.1
ENST00000396150.4
ZNF586





zinc finger protein 586





chr3_-_69101461 0.474 ENST00000543976.1
TMF1
TATA element modulatory factor 1
chr17_+_10600894 0.463 ENST00000379774.4
ADPRM
ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
chr6_-_132834184 0.461 ENST00000367941.2
ENST00000367937.4
STX7

syntaxin 7

chr14_-_23426270 0.457 ENST00000557591.1
ENST00000397409.4
ENST00000490506.1
ENST00000554406.1
HAUS4



HAUS augmin-like complex, subunit 4



chr14_+_77787227 0.446 ENST00000216465.5
ENST00000361389.4
ENST00000554279.1
ENST00000557639.1
ENST00000349555.3
ENST00000556627.1
ENST00000557053.1
GSTZ1






glutathione S-transferase zeta 1






chr4_-_8442438 0.443 ENST00000356406.5
ENST00000413009.2
ACOX3

acyl-CoA oxidase 3, pristanoyl

chr12_+_66582919 0.440 ENST00000545837.1
ENST00000457197.2
IRAK3

interleukin-1 receptor-associated kinase 3

chr19_-_19774473 0.435 ENST00000357324.6
ATP13A1
ATPase type 13A1
chr15_-_81616446 0.434 ENST00000302824.6
STARD5
StAR-related lipid transfer (START) domain containing 5
chr17_-_3599327 0.430 ENST00000551178.1
ENST00000552276.1
ENST00000547178.1
P2RX5


purinergic receptor P2X, ligand-gated ion channel, 5


chr14_-_23426337 0.414 ENST00000342454.8
ENST00000555986.1
ENST00000541587.1
ENST00000554516.1
ENST00000347758.2
ENST00000206474.7
ENST00000555040.1
HAUS4






HAUS augmin-like complex, subunit 4






chrX_+_2609207 0.412 ENST00000381192.3
CD99
CD99 molecule
chr6_-_26250835 0.412 ENST00000446824.2
HIST1H3F
histone cluster 1, H3f
chr9_-_19127474 0.405 ENST00000380465.3
ENST00000380464.3
ENST00000411567.1
ENST00000276914.2
PLIN2



perilipin 2



chr1_+_168195229 0.403 ENST00000271375.4
ENST00000367825.3
SFT2D2

SFT2 domain containing 2

chr14_+_72064945 0.402 ENST00000537413.1
SIPA1L1
signal-induced proliferation-associated 1 like 1
chr14_-_23426322 0.399 ENST00000555367.1
HAUS4
HAUS augmin-like complex, subunit 4
chr7_-_95225768 0.395 ENST00000005178.5
PDK4
pyruvate dehydrogenase kinase, isozyme 4
chr7_-_22234381 0.394 ENST00000458533.1
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr6_-_33282163 0.392 ENST00000434618.2
ENST00000456592.2
TAPBP

TAP binding protein (tapasin)

chr12_-_108714412 0.388 ENST00000412676.1
ENST00000550573.1
CMKLR1

chemokine-like receptor 1

chr3_-_53880401 0.388 ENST00000315251.6
CHDH
choline dehydrogenase
chr2_-_89521942 0.381 ENST00000482769.1
IGKV2-28
immunoglobulin kappa variable 2-28
chr2_+_219110149 0.380 ENST00000456575.1
ARPC2
actin related protein 2/3 complex, subunit 2, 34kDa
chr3_-_11623804 0.379 ENST00000451674.2
VGLL4
vestigial like 4 (Drosophila)
chr2_+_89998789 0.375 ENST00000453166.2
IGKV2D-28
immunoglobulin kappa variable 2D-28
chr22_+_39410088 0.374 ENST00000361441.4
APOBEC3C
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
chr15_-_64126084 0.373 ENST00000560316.1
ENST00000443617.2
ENST00000560462.1
ENST00000558532.1
ENST00000561400.1
HERC1




HECT and RLD domain containing E3 ubiquitin protein ligase family member 1




chr12_-_498620 0.372 ENST00000399788.2
ENST00000382815.4
KDM5A

lysine (K)-specific demethylase 5A

chr17_+_4843303 0.372 ENST00000571816.1
RNF167
ring finger protein 167
chr11_-_85376121 0.370 ENST00000527447.1
CREBZF
CREB/ATF bZIP transcription factor
chrX_+_2609317 0.367 ENST00000381187.3
ENST00000381184.1
CD99

CD99 molecule

chr20_+_43160409 0.365 ENST00000372894.3
ENST00000372892.3
ENST00000372891.3
PKIG


protein kinase (cAMP-dependent, catalytic) inhibitor gamma


chr10_+_120863587 0.365 ENST00000535029.1
ENST00000361432.2
ENST00000544016.1
FAM45A


family with sequence similarity 45, member A


chr19_+_36157715 0.360 ENST00000379013.2
ENST00000222275.2
UPK1A

uroplakin 1A

chr20_+_45947246 0.358 ENST00000599904.1
AL031666.2
HCG2018772; Uncharacterized protein; cDNA FLJ31609 fis, clone NT2RI2002852
chr6_+_26045603 0.358 ENST00000540144.1
HIST1H3C
histone cluster 1, H3c
chr3_-_66551397 0.356 ENST00000383703.3
LRIG1
leucine-rich repeats and immunoglobulin-like domains 1
chr19_+_8117881 0.354 ENST00000390669.3
CCL25
chemokine (C-C motif) ligand 25
chr3_-_119396193 0.352 ENST00000484810.1
ENST00000497116.1
ENST00000261070.2
COX17


COX17 cytochrome c oxidase copper chaperone


chr3_+_73110810 0.351 ENST00000533473.1
EBLN2
endogenous Bornavirus-like nucleoprotein 2
chr5_+_125935960 0.349 ENST00000297540.4
PHAX
phosphorylated adaptor for RNA export
chr2_-_70418032 0.348 ENST00000425268.1
ENST00000428751.1
ENST00000417203.1
ENST00000417865.1
ENST00000428010.1
ENST00000447804.1
ENST00000264434.2
C2orf42






chromosome 2 open reading frame 42







Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.5 1.6 GO:0035419 activation of MAPK activity involved in innate immune response(GO:0035419)
0.5 2.9 GO:2000124 cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926) regulation of endocannabinoid signaling pathway(GO:2000124)
0.5 3.4 GO:0045627 regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423) positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425) positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.5 10.2 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.4 2.2 GO:0060292 long term synaptic depression(GO:0060292)
0.3 18.5 GO:0006958 complement activation, classical pathway(GO:0006958)
0.3 0.9 GO:0035608 protein deglutamylation(GO:0035608)
0.3 0.9 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.3 4.7 GO:0018298 protein-chromophore linkage(GO:0018298)
0.3 1.4 GO:0071356 tumor necrosis factor-mediated signaling pathway(GO:0033209) response to tumor necrosis factor(GO:0034612) cellular response to tumor necrosis factor(GO:0071356)
0.2 0.9 GO:0006154 adenosine catabolic process(GO:0006154)
0.2 0.8 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.2 1.0 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180)
0.2 0.6 GO:0045656 negative regulation of monocyte differentiation(GO:0045656)
0.2 0.6 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.2 1.7 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.2 0.8 GO:0046967 cytosol to ER transport(GO:0046967)
0.2 0.5 GO:0071380 cellular response to prostaglandin E stimulus(GO:0071380)
0.2 1.1 GO:0015755 fructose transport(GO:0015755)
0.2 0.5 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.1 0.4 GO:0034122 negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.1 0.9 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.1 1.0 GO:0010459 negative regulation of heart rate(GO:0010459)
0.1 0.4 GO:0006423 cysteinyl-tRNA aminoacylation(GO:0006423)
0.1 1.2 GO:0006546 glycine catabolic process(GO:0006546)
0.1 2.7 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.1 1.2 GO:0015074 DNA integration(GO:0015074)
0.1 0.7 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.1 0.6 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1 1.0 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 0.3 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.1 1.6 GO:0043330 response to exogenous dsRNA(GO:0043330)
0.1 0.8 GO:0021978 telencephalon regionalization(GO:0021978)
0.1 0.7 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 1.4 GO:0071230 positive regulation of TOR signaling(GO:0032008) cellular response to amino acid stimulus(GO:0071230)
0.1 0.1 GO:0046110 xanthine metabolic process(GO:0046110)
0.1 0.5 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.1 0.3 GO:0006408 snRNA export from nucleus(GO:0006408) snRNA transport(GO:0051030)
0.1 0.9 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.1 1.5 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.1 0.4 GO:0018106 peptidyl-histidine phosphorylation(GO:0018106)
0.1 0.2 GO:0031297 replication fork processing(GO:0031297)
0.1 0.7 GO:0051552 flavone metabolic process(GO:0051552)
0.1 1.9 GO:0030224 monocyte differentiation(GO:0030224)
0.1 0.4 GO:0010759 regulation of macrophage chemotaxis(GO:0010758) positive regulation of macrophage chemotaxis(GO:0010759)
0.1 0.9 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.1 0.7 GO:0007141 male meiosis I(GO:0007141)
0.1 1.2 GO:0070206 protein trimerization(GO:0070206)
0.1 0.4 GO:0048296 isotype switching to IgA isotypes(GO:0048290) regulation of isotype switching to IgA isotypes(GO:0048296) positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.1 1.6 GO:0030593 neutrophil chemotaxis(GO:0030593) neutrophil migration(GO:1990266)
0.1 0.2 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.1 1.1 GO:0031648 protein destabilization(GO:0031648)
0.1 0.2 GO:1901361 heterocycle catabolic process(GO:0046700) organic cyclic compound catabolic process(GO:1901361)
0.1 1.2 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.1 1.9 GO:0045646 regulation of erythrocyte differentiation(GO:0045646)
0.1 0.2 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.1 0.8 GO:0015939 pantothenate metabolic process(GO:0015939)
0.1 0.4 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 0.3 GO:0060259 regulation of feeding behavior(GO:0060259)
0.1 0.8 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 1.8 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.2 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.0 0.3 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.3 GO:0046349 UDP-N-acetylglucosamine biosynthetic process(GO:0006048) amino sugar biosynthetic process(GO:0046349)
0.0 0.8 GO:0008634 obsolete negative regulation of survival gene product expression(GO:0008634)
0.0 0.1 GO:0002681 somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153) DNA ligation involved in DNA recombination(GO:0051102)
0.0 1.3 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.0 0.7 GO:0030260 entry into host cell(GO:0030260) entry into host(GO:0044409) entry into cell of other organism involved in symbiotic interaction(GO:0051806) entry into other organism involved in symbiotic interaction(GO:0051828)
0.0 3.0 GO:0006968 cellular defense response(GO:0006968)
0.0 0.3 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 3.3 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
0.0 0.4 GO:0060968 regulation of gene silencing(GO:0060968)
0.0 0.4 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0 0.1 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.0 0.1 GO:0050983 spermidine catabolic process(GO:0046203) deoxyhypusine biosynthetic process from spermidine(GO:0050983)
0.0 0.7 GO:0007032 endosome organization(GO:0007032)
0.0 0.1 GO:0043116 negative regulation of vascular permeability(GO:0043116)
0.0 0.1 GO:0060649 nipple development(GO:0060618) mammary gland bud elongation(GO:0060649) nipple morphogenesis(GO:0060658) nipple sheath formation(GO:0060659)
0.0 0.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 3.2 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 0.4 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.0 0.0 GO:2000078 regulation of type B pancreatic cell development(GO:2000074) positive regulation of type B pancreatic cell development(GO:2000078)
0.0 0.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.6 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.2 GO:0045010 actin nucleation(GO:0045010)
0.0 0.1 GO:0043114 regulation of vascular permeability(GO:0043114)
0.0 0.1 GO:0071624 positive regulation of granulocyte chemotaxis(GO:0071624)
0.0 0.1 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.2 GO:0006477 protein sulfation(GO:0006477)
0.0 0.2 GO:0071692 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.1 GO:0070935 positive regulation of chemokine biosynthetic process(GO:0045080) 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.2 GO:0030855 epithelial cell differentiation(GO:0030855)
0.0 0.4 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.7 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.0 0.1 GO:0060744 thelarche(GO:0042695) development of secondary female sexual characteristics(GO:0046543) mammary gland branching involved in thelarche(GO:0060744)
0.0 0.0 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.2 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0 0.1 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.0 1.4 GO:0006959 humoral immune response(GO:0006959)
0.0 0.2 GO:0001510 RNA methylation(GO:0001510)
0.0 0.1 GO:0060084 acetylcholine secretion, neurotransmission(GO:0014055) regulation of acetylcholine secretion, neurotransmission(GO:0014056) synaptic transmission involved in micturition(GO:0060084) acetylcholine secretion(GO:0061526)
0.0 1.1 GO:0051297 centrosome organization(GO:0051297)
0.0 0.1 GO:0046618 drug transmembrane transport(GO:0006855) tetracycline transport(GO:0015904) drug export(GO:0046618)
0.0 0.6 GO:0006309 DNA catabolic process, endonucleolytic(GO:0000737) apoptotic DNA fragmentation(GO:0006309)
0.0 0.1 GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.0 1.0 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.5 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 0.5 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.1 GO:0035313 wound healing, spreading of epidermal cells(GO:0035313) wound healing, spreading of cells(GO:0044319) epiboly(GO:0090504) epiboly involved in wound healing(GO:0090505)
0.0 0.4 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.5 GO:0006397 mRNA processing(GO:0006397)
0.0 0.4 GO:0006825 copper ion transport(GO:0006825)
0.0 0.3 GO:0001938 positive regulation of endothelial cell proliferation(GO:0001938)
0.0 0.1 GO:0045003 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 0.3 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.3 GO:0031055 DNA replication-independent nucleosome assembly(GO:0006336) chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) DNA replication-independent nucleosome organization(GO:0034724) CENP-A containing chromatin organization(GO:0061641)
0.0 0.1 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.0 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.3 GO:0030838 positive regulation of actin filament polymerization(GO:0030838)
0.0 0.1 GO:0030157 pancreatic juice secretion(GO:0030157)
0.0 0.1 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.1 GO:0006553 lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0 0.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 1.6 GO:0030155 regulation of cell adhesion(GO:0030155)
0.0 0.2 GO:0046037 GMP metabolic process(GO:0046037)
0.0 0.3 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.9 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.0 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.4 GO:1900181 negative regulation of protein import into nucleus(GO:0042308) negative regulation of protein localization to nucleus(GO:1900181) negative regulation of protein import(GO:1904590)
0.0 0.1 GO:0042976 activation of Janus kinase activity(GO:0042976) activation of JAK2 kinase activity(GO:0042977)
0.0 0.1 GO:0002860 natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 0.1 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.2 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.1 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.1 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.3 GO:0006672 ceramide metabolic process(GO:0006672)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 13.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.4 1.1 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.3 2.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.3 1.0 GO:0097651 phosphatidylinositol 3-kinase complex, class IA(GO:0005943) phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.2 1.2 GO:0019815 immunoglobulin complex(GO:0019814) B cell receptor complex(GO:0019815)
0.2 0.6 GO:0042629 mast cell granule(GO:0042629)
0.2 0.7 GO:0000800 lateral element(GO:0000800)
0.2 0.6 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.1 1.3 GO:0070652 HAUS complex(GO:0070652)
0.1 3.2 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 3.7 GO:0005839 proteasome core complex(GO:0005839)
0.1 0.8 GO:0042825 TAP complex(GO:0042825)
0.1 1.0 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 0.4 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.1 0.3 GO:0070188 obsolete Stn1-Ten1 complex(GO:0070188)
0.1 1.8 GO:0001533 cornified envelope(GO:0001533)
0.1 0.2 GO:0005873 plus-end kinesin complex(GO:0005873)
0.1 1.4 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.1 0.3 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 2.1 GO:0098636 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.6 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.7 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.2 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.5 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.3 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.3 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.3 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.5 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.9 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.2 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.1 GO:0060171 stereocilium membrane(GO:0060171)
0.0 1.4 GO:0015030 Cajal body(GO:0015030)
0.0 1.2 GO:0000786 nucleosome(GO:0000786)
0.0 0.2 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.2 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.3 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.5 GO:0031201 SNARE complex(GO:0031201)
0.0 0.0 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 2.7 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.2 GO:0001527 microfibril(GO:0001527)
0.0 0.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.3 GO:0005844 polysome(GO:0005844)
0.0 0.2 GO:0030914 STAGA complex(GO:0030914)
0.0 0.5 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.3 GO:0000299 obsolete integral to membrane of membrane fraction(GO:0000299)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)
0.0 0.2 GO:0045178 basal part of cell(GO:0045178)
0.0 1.8 GO:0005769 early endosome(GO:0005769)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:0042289 MHC class II protein binding(GO:0042289)
0.7 2.2 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.5 31.5 GO:0003823 antigen binding(GO:0003823)
0.5 6.8 GO:0032395 MHC class II receptor activity(GO:0032395)
0.3 1.0 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.3 0.9 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.3 1.2 GO:0008907 integrase activity(GO:0008907)
0.2 0.7 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.2 1.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.2 2.7 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.2 0.6 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.2 3.0 GO:0032393 MHC class I receptor activity(GO:0032393)
0.2 0.6 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.2 1.0 GO:0043559 insulin binding(GO:0043559)
0.2 1.1 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.1 0.4 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
0.1 0.4 GO:0004817 cysteine-tRNA ligase activity(GO:0004817)
0.1 4.3 GO:0015026 coreceptor activity(GO:0015026)
0.1 3.7 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 1.2 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 1.1 GO:0004000 adenosine deaminase activity(GO:0004000)
0.1 2.4 GO:0016805 dipeptidase activity(GO:0016805)
0.1 0.5 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.1 0.4 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.4 GO:0016531 copper chaperone activity(GO:0016531)
0.1 1.3 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.1 0.5 GO:0050700 CARD domain binding(GO:0050700)
0.1 0.3 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.1 0.2 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.1 0.4 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.3 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.1 0.3 GO:0042910 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.1 1.8 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 0.7 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 0.2 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 1.2 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.1 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.3 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.2 GO:0033981 D-dopachrome decarboxylase activity(GO:0033981)
0.0 0.6 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.6 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.1 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.0 0.7 GO:0005521 lamin binding(GO:0005521)
0.0 0.9 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.9 GO:0043621 protein self-association(GO:0043621)
0.0 0.6 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.4 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.1 GO:0034038 deoxyhypusine synthase activity(GO:0034038)
0.0 0.3 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 1.1 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 1.5 GO:0002020 protease binding(GO:0002020)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.6 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.5 GO:0003840 gamma-glutamyltransferase activity(GO:0003840)
0.0 0.8 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.3 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.3 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.1 GO:0030151 molybdenum ion binding(GO:0030151)
0.0 0.7 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.1 GO:0015520 tetracycline:proton antiporter activity(GO:0015520)
0.0 0.1 GO:0004146 dihydrofolate reductase activity(GO:0004146)
0.0 0.5 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 0.2 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.3 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.4 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 1.5 GO:0001948 glycoprotein binding(GO:0001948)
0.0 2.4 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.1 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.1 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.0 0.2 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.2 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.6 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.2 GO:1901567 icosanoid binding(GO:0050542) arachidonic acid binding(GO:0050544) fatty acid derivative binding(GO:1901567)
0.0 0.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.2 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.4 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.1 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.7 GO:0005518 collagen binding(GO:0005518)
0.0 0.4 GO:0016566 obsolete specific transcriptional repressor activity(GO:0016566)
0.0 2.7 GO:0003702 obsolete RNA polymerase II transcription factor activity(GO:0003702)
0.0 0.9 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.0 GO:0004797 thymidine kinase activity(GO:0004797)
0.0 0.8 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.4 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.1 GO:0050780 dopamine receptor binding(GO:0050780)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.6 GO:0008009 chemokine activity(GO:0008009)
0.0 0.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.1 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.2 GO:0030276 clathrin binding(GO:0030276)
0.0 0.2 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.9 GO:0005178 integrin binding(GO:0005178)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 ST_TYPE_I_INTERFERON_PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.1 1.7 SIG_IL4RECEPTOR_IN_B_LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 3.0 ST_G_ALPHA_I_PATHWAY G alpha i Pathway
0.0 1.8 SIG_BCR_SIGNALING_PATHWAY Members of the BCR signaling pathway
0.0 0.8 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.1 SA_B_CELL_RECEPTOR_COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.3 ST_GRANULE_CELL_SURVIVAL_PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.5 ST_GA13_PATHWAY G alpha 13 Pathway