Motif ID: NR5A2
Z-value: 2.065
Transcription factors associated with NR5A2:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| NR5A2 | ENSG00000116833.9 | NR5A2 |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 0.8 | GO:0042701 | progesterone secretion(GO:0042701) |
| 0.6 | 3.1 | GO:0015670 | carbon dioxide transport(GO:0015670) |
| 0.6 | 1.8 | GO:0046521 | sphingoid catabolic process(GO:0046521) |
| 0.5 | 2.1 | GO:0002318 | myeloid progenitor cell differentiation(GO:0002318) |
| 0.4 | 1.2 | GO:0042759 | long-chain fatty acid biosynthetic process(GO:0042759) |
| 0.4 | 1.2 | GO:0070171 | negative regulation of tooth mineralization(GO:0070171) |
| 0.4 | 1.1 | GO:0006106 | fumarate metabolic process(GO:0006106) |
| 0.3 | 1.0 | GO:0015959 | diadenosine polyphosphate metabolic process(GO:0015959) |
| 0.3 | 2.1 | GO:0071372 | cellular response to follicle-stimulating hormone stimulus(GO:0071372) |
| 0.3 | 1.7 | GO:0030952 | establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) establishment or maintenance of cytoskeleton polarity(GO:0030952) |
| 0.3 | 1.0 | GO:0010248 | establishment or maintenance of transmembrane electrochemical gradient(GO:0010248) post-embryonic camera-type eye development(GO:0031077) |
| 0.3 | 2.1 | GO:0006177 | GMP biosynthetic process(GO:0006177) |
| 0.3 | 0.9 | GO:0006432 | phenylalanyl-tRNA aminoacylation(GO:0006432) |
| 0.3 | 0.8 | GO:0009648 | photoperiodism(GO:0009648) |
| 0.3 | 1.0 | GO:0045299 | otolith mineralization(GO:0045299) |
| 0.3 | 2.0 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
| 0.2 | 1.4 | GO:0045654 | positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534) |
| 0.2 | 1.6 | GO:0016584 | nucleosome positioning(GO:0016584) |
| 0.2 | 1.9 | GO:0006600 | creatine metabolic process(GO:0006600) |
| 0.2 | 1.5 | GO:0045647 | negative regulation of erythrocyte differentiation(GO:0045647) |
| 0.2 | 1.3 | GO:0071243 | uroporphyrinogen III metabolic process(GO:0046502) response to fungicide(GO:0060992) cellular response to arsenic-containing substance(GO:0071243) |
| 0.2 | 0.5 | GO:0051083 | 'de novo' cotranslational protein folding(GO:0051083) |
| 0.2 | 0.5 | GO:0010902 | positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902) positive regulation of phospholipid catabolic process(GO:0060697) |
| 0.2 | 1.2 | GO:0006855 | drug transmembrane transport(GO:0006855) |
| 0.2 | 0.5 | GO:1904742 | regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381) regulation of telomeric DNA binding(GO:1904742) positive regulation of telomeric DNA binding(GO:1904744) |
| 0.2 | 0.6 | GO:0045048 | protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816) |
| 0.2 | 1.1 | GO:0070934 | CRD-mediated mRNA stabilization(GO:0070934) |
| 0.2 | 0.6 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
| 0.2 | 2.4 | GO:0046902 | regulation of mitochondrial membrane permeability(GO:0046902) regulation of membrane permeability(GO:0090559) |
| 0.1 | 1.0 | GO:0040032 | post-embryonic body morphogenesis(GO:0040032) |
| 0.1 | 1.3 | GO:0006105 | succinate metabolic process(GO:0006105) |
| 0.1 | 0.4 | GO:0090034 | regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035) |
| 0.1 | 0.5 | GO:0019827 | stem cell population maintenance(GO:0019827) maintenance of cell number(GO:0098727) |
| 0.1 | 1.6 | GO:0008635 | activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635) |
| 0.1 | 1.5 | GO:0010042 | response to manganese ion(GO:0010042) |
| 0.1 | 0.4 | GO:0060013 | righting reflex(GO:0060013) |
| 0.1 | 0.8 | GO:0071267 | amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267) |
| 0.1 | 1.1 | GO:0051918 | negative regulation of fibrinolysis(GO:0051918) |
| 0.1 | 0.5 | GO:0009298 | GDP-mannose biosynthetic process(GO:0009298) |
| 0.1 | 0.4 | GO:0006682 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
| 0.1 | 0.3 | GO:0030205 | dermatan sulfate metabolic process(GO:0030205) dermatan sulfate biosynthetic process(GO:0030208) |
| 0.1 | 0.8 | GO:0000959 | mitochondrial RNA metabolic process(GO:0000959) transcription from mitochondrial promoter(GO:0006390) |
| 0.1 | 0.3 | GO:0021529 | spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780) |
| 0.1 | 1.9 | GO:0032012 | regulation of ARF protein signal transduction(GO:0032012) |
| 0.1 | 0.4 | GO:0009106 | lipoate metabolic process(GO:0009106) |
| 0.1 | 0.4 | GO:0006384 | transcription initiation from RNA polymerase III promoter(GO:0006384) |
| 0.1 | 0.9 | GO:0035095 | behavioral response to nicotine(GO:0035095) |
| 0.1 | 0.9 | GO:0033137 | negative regulation of peptidyl-serine phosphorylation(GO:0033137) |
| 0.1 | 0.6 | GO:0043457 | regulation of cellular respiration(GO:0043457) |
| 0.1 | 0.4 | GO:0051013 | microtubule severing(GO:0051013) |
| 0.1 | 0.3 | GO:0048075 | positive regulation of eye pigmentation(GO:0048075) |
| 0.1 | 0.3 | GO:0016188 | synaptic vesicle maturation(GO:0016188) |
| 0.1 | 0.5 | GO:0034501 | protein localization to kinetochore(GO:0034501) |
| 0.1 | 0.3 | GO:0032486 | Rap protein signal transduction(GO:0032486) |
| 0.1 | 1.2 | GO:0097031 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
| 0.1 | 0.3 | GO:0019605 | butyrate metabolic process(GO:0019605) |
| 0.1 | 1.0 | GO:0051489 | regulation of filopodium assembly(GO:0051489) |
| 0.1 | 3.1 | GO:0006626 | protein targeting to mitochondrion(GO:0006626) |
| 0.1 | 0.5 | GO:0035058 | nonmotile primary cilium assembly(GO:0035058) |
| 0.1 | 6.0 | GO:0006334 | nucleosome assembly(GO:0006334) |
| 0.1 | 0.5 | GO:0042448 | progesterone metabolic process(GO:0042448) |
| 0.1 | 0.2 | GO:0002125 | maternal aggressive behavior(GO:0002125) obsolete negative regulation of diuresis(GO:0003077) positive regulation of norepinephrine secretion(GO:0010701) |
| 0.1 | 0.2 | GO:0021571 | rhombomere 4 development(GO:0021570) rhombomere 5 development(GO:0021571) facial nucleus development(GO:0021754) |
| 0.1 | 0.3 | GO:0048739 | cardiac muscle fiber development(GO:0048739) |
| 0.1 | 0.3 | GO:0051140 | tyrosine phosphorylation of Stat4 protein(GO:0042504) regulation of tyrosine phosphorylation of Stat4 protein(GO:0042519) positive regulation of tyrosine phosphorylation of Stat4 protein(GO:0042520) regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142) |
| 0.1 | 0.3 | GO:0001955 | blood vessel maturation(GO:0001955) blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043) |
| 0.1 | 0.7 | GO:0006027 | glycosaminoglycan catabolic process(GO:0006027) |
| 0.1 | 0.4 | GO:0043045 | DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538) |
| 0.1 | 0.2 | GO:0035623 | renal glucose absorption(GO:0035623) |
| 0.1 | 0.6 | GO:0032000 | positive regulation of fatty acid beta-oxidation(GO:0032000) |
| 0.1 | 0.8 | GO:0045823 | positive regulation of heart contraction(GO:0045823) |
| 0.1 | 0.1 | GO:1903960 | regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192) |
| 0.1 | 0.5 | GO:0006107 | oxaloacetate metabolic process(GO:0006107) |
| 0.1 | 0.3 | GO:0048550 | positive regulation of triglyceride biosynthetic process(GO:0010867) negative regulation of pinocytosis(GO:0048550) |
| 0.1 | 0.9 | GO:0001976 | neurological system process involved in regulation of systemic arterial blood pressure(GO:0001976) |
| 0.1 | 0.2 | GO:0048537 | mucosal-associated lymphoid tissue development(GO:0048537) |
| 0.1 | 0.2 | GO:0070995 | NADPH oxidation(GO:0070995) |
| 0.0 | 0.3 | GO:0010523 | negative regulation of calcium ion transport into cytosol(GO:0010523) |
| 0.0 | 0.6 | GO:0034643 | establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497) |
| 0.0 | 0.2 | GO:0050857 | positive regulation of antigen receptor-mediated signaling pathway(GO:0050857) positive regulation of T cell receptor signaling pathway(GO:0050862) |
| 0.0 | 0.2 | GO:0032754 | positive regulation of interleukin-5 production(GO:0032754) |
| 0.0 | 0.2 | GO:0007016 | cytoskeletal anchoring at plasma membrane(GO:0007016) |
| 0.0 | 0.2 | GO:0040034 | regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505) |
| 0.0 | 1.4 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
| 0.0 | 0.3 | GO:0070059 | intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059) |
| 0.0 | 0.2 | GO:0060025 | regulation of synaptic activity(GO:0060025) |
| 0.0 | 0.8 | GO:0018298 | protein-chromophore linkage(GO:0018298) |
| 0.0 | 0.2 | GO:0060014 | granulosa cell differentiation(GO:0060014) |
| 0.0 | 1.2 | GO:0060761 | negative regulation of response to cytokine stimulus(GO:0060761) |
| 0.0 | 1.0 | GO:0043101 | purine-containing compound salvage(GO:0043101) |
| 0.0 | 0.3 | GO:0006103 | 2-oxoglutarate metabolic process(GO:0006103) |
| 0.0 | 0.5 | GO:0006099 | tricarboxylic acid cycle(GO:0006099) |
| 0.0 | 0.1 | GO:0006382 | adenosine to inosine editing(GO:0006382) |
| 0.0 | 0.2 | GO:0032916 | transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910) positive regulation of transforming growth factor beta3 production(GO:0032916) |
| 0.0 | 0.8 | GO:1903078 | positive regulation of establishment of protein localization to plasma membrane(GO:0090004) positive regulation of protein localization to plasma membrane(GO:1903078) positive regulation of protein localization to cell periphery(GO:1904377) |
| 0.0 | 0.1 | GO:1903115 | regulation of muscle filament sliding(GO:0032971) regulation of actin filament-based movement(GO:1903115) |
| 0.0 | 0.7 | GO:0000303 | response to superoxide(GO:0000303) |
| 0.0 | 0.2 | GO:0018106 | peptidyl-histidine phosphorylation(GO:0018106) |
| 0.0 | 0.2 | GO:0034616 | response to laminar fluid shear stress(GO:0034616) |
| 0.0 | 0.8 | GO:0046627 | negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077) |
| 0.0 | 0.2 | GO:0006642 | triglyceride mobilization(GO:0006642) |
| 0.0 | 0.4 | GO:0030097 | hemopoiesis(GO:0030097) |
| 0.0 | 0.1 | GO:0045218 | zonula adherens maintenance(GO:0045218) |
| 0.0 | 0.1 | GO:0043653 | mitochondrial fragmentation involved in apoptotic process(GO:0043653) |
| 0.0 | 0.7 | GO:0035338 | long-chain fatty-acyl-CoA metabolic process(GO:0035336) long-chain fatty-acyl-CoA biosynthetic process(GO:0035338) |
| 0.0 | 0.3 | GO:0006743 | ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) |
| 0.0 | 0.3 | GO:0002756 | MyD88-independent toll-like receptor signaling pathway(GO:0002756) |
| 0.0 | 0.6 | GO:0007597 | blood coagulation, intrinsic pathway(GO:0007597) |
| 0.0 | 0.2 | GO:0000266 | mitochondrial fission(GO:0000266) |
| 0.0 | 0.5 | GO:0006386 | transcription elongation from RNA polymerase III promoter(GO:0006385) termination of RNA polymerase III transcription(GO:0006386) |
| 0.0 | 0.7 | GO:0050853 | B cell receptor signaling pathway(GO:0050853) |
| 0.0 | 0.3 | GO:0006665 | sphingolipid metabolic process(GO:0006665) |
| 0.0 | 0.2 | GO:0006572 | tyrosine catabolic process(GO:0006572) |
| 0.0 | 0.2 | GO:0009060 | aerobic respiration(GO:0009060) |
| 0.0 | 0.4 | GO:0045070 | positive regulation of viral genome replication(GO:0045070) |
| 0.0 | 2.1 | GO:0030218 | erythrocyte differentiation(GO:0030218) |
| 0.0 | 0.7 | GO:0051156 | glucose 6-phosphate metabolic process(GO:0051156) |
| 0.0 | 0.1 | GO:0043306 | positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of leukocyte degranulation(GO:0043302) positive regulation of mast cell degranulation(GO:0043306) |
| 0.0 | 0.3 | GO:0050812 | acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812) |
| 0.0 | 0.4 | GO:0006400 | tRNA modification(GO:0006400) |
| 0.0 | 1.6 | GO:0034599 | cellular response to oxidative stress(GO:0034599) |
| 0.0 | 0.2 | GO:0060046 | regulation of acrosome reaction(GO:0060046) |
| 0.0 | 0.1 | GO:0030157 | pancreatic juice secretion(GO:0030157) |
| 0.0 | 2.4 | GO:0045333 | cellular respiration(GO:0045333) |
| 0.0 | 0.6 | GO:0019370 | leukotriene biosynthetic process(GO:0019370) |
| 0.0 | 0.6 | GO:0031648 | protein destabilization(GO:0031648) |
| 0.0 | 0.1 | GO:0009450 | gamma-aminobutyric acid metabolic process(GO:0009448) gamma-aminobutyric acid catabolic process(GO:0009450) |
| 0.0 | 1.5 | GO:0070588 | calcium ion transmembrane transport(GO:0070588) |
| 0.0 | 1.1 | GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184) |
| 0.0 | 0.0 | GO:0002634 | regulation of germinal center formation(GO:0002634) |
| 0.0 | 0.1 | GO:0046952 | ketone body catabolic process(GO:0046952) |
| 0.0 | 0.7 | GO:0007030 | Golgi organization(GO:0007030) |
| 0.0 | 0.4 | GO:0043278 | response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278) |
| 0.0 | 0.3 | GO:0007168 | receptor guanylyl cyclase signaling pathway(GO:0007168) |
| 0.0 | 0.3 | GO:0030252 | growth hormone secretion(GO:0030252) |
| 0.0 | 0.1 | GO:0071801 | podosome assembly(GO:0071800) regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803) |
| 0.0 | 0.2 | GO:0035964 | COPI-coated vesicle budding(GO:0035964) Golgi vesicle budding(GO:0048194) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205) |
| 0.0 | 0.1 | GO:0030382 | sperm mitochondrion organization(GO:0030382) |
| 0.0 | 0.5 | GO:0007190 | activation of adenylate cyclase activity(GO:0007190) |
| 0.0 | 0.6 | GO:0006362 | transcription elongation from RNA polymerase I promoter(GO:0006362) |
| 0.0 | 0.2 | GO:0045776 | negative regulation of blood pressure(GO:0045776) |
| 0.0 | 0.6 | GO:0030010 | establishment of cell polarity(GO:0030010) |
| 0.0 | 0.6 | GO:0043154 | negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154) |
| 0.0 | 0.2 | GO:0000183 | chromatin silencing at rDNA(GO:0000183) |
| 0.0 | 0.1 | GO:0051965 | positive regulation of synapse assembly(GO:0051965) |
| 0.0 | 0.5 | GO:0098657 | neurotransmitter uptake(GO:0001504) import into cell(GO:0098657) |
| 0.0 | 0.7 | GO:0032436 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800) |
| 0.0 | 0.7 | GO:0006611 | protein export from nucleus(GO:0006611) |
| 0.0 | 1.3 | GO:0031214 | biomineral tissue development(GO:0031214) |
| 0.0 | 0.5 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
| 0.0 | 0.3 | GO:1901224 | activation of NF-kappaB-inducing kinase activity(GO:0007250) NIK/NF-kappaB signaling(GO:0038061) regulation of NIK/NF-kappaB signaling(GO:1901222) positive regulation of NIK/NF-kappaB signaling(GO:1901224) |
| 0.0 | 0.3 | GO:0010745 | negative regulation of macrophage derived foam cell differentiation(GO:0010745) |
| 0.0 | 0.4 | GO:0006662 | glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904) |
| 0.0 | 0.1 | GO:0008354 | germ cell migration(GO:0008354) |
| 0.0 | 0.2 | GO:0048536 | spleen development(GO:0048536) |
| 0.0 | 0.2 | GO:0048096 | chromatin-mediated maintenance of transcription(GO:0048096) |
| 0.0 | 0.2 | GO:0016572 | histone phosphorylation(GO:0016572) |
| 0.0 | 0.9 | GO:0006458 | 'de novo' protein folding(GO:0006458) |
| 0.0 | 0.7 | GO:0006369 | termination of RNA polymerase II transcription(GO:0006369) |
| 0.0 | 0.2 | GO:0035235 | ionotropic glutamate receptor signaling pathway(GO:0035235) |
| 0.0 | 0.2 | GO:0030212 | hyaluronan metabolic process(GO:0030212) |
| 0.0 | 0.4 | GO:0050999 | regulation of nitric-oxide synthase activity(GO:0050999) |
| 0.0 | 0.1 | GO:0006646 | phosphatidylethanolamine biosynthetic process(GO:0006646) phosphatidylethanolamine metabolic process(GO:0046337) |
| 0.0 | 0.1 | GO:0033363 | secretory granule organization(GO:0033363) |
| 0.0 | 0.1 | GO:0001867 | complement activation, lectin pathway(GO:0001867) |
| 0.0 | 0.3 | GO:0030593 | neutrophil chemotaxis(GO:0030593) neutrophil migration(GO:1990266) |
| 0.0 | 0.4 | GO:0071804 | cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805) |
| 0.0 | 0.2 | GO:0046854 | phosphatidylinositol phosphorylation(GO:0046854) |
| 0.0 | 0.5 | GO:0006506 | GPI anchor biosynthetic process(GO:0006506) |
| 0.0 | 0.1 | GO:0050668 | positive regulation of sulfur amino acid metabolic process(GO:0031337) positive regulation of cellular amino acid metabolic process(GO:0045764) negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963) positive regulation of homocysteine metabolic process(GO:0050668) |
| 0.0 | 0.1 | GO:0007090 | obsolete regulation of S phase of mitotic cell cycle(GO:0007090) |
| 0.0 | 0.1 | GO:0001880 | Mullerian duct regression(GO:0001880) |
| 0.0 | 0.1 | GO:0090231 | regulation of spindle checkpoint(GO:0090231) |
| 0.0 | 0.1 | GO:0001947 | heart looping(GO:0001947) embryonic heart tube morphogenesis(GO:0003143) determination of heart left/right asymmetry(GO:0061371) |
| 0.0 | 0.6 | GO:0009187 | cyclic nucleotide metabolic process(GO:0009187) |
| 0.0 | 0.0 | GO:0048935 | peripheral nervous system neuron development(GO:0048935) |
| 0.0 | 1.0 | GO:0008360 | regulation of cell shape(GO:0008360) |
| 0.0 | 0.0 | GO:0031282 | regulation of guanylate cyclase activity(GO:0031282) |
| 0.0 | 0.3 | GO:0051925 | obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925) |
| 0.0 | 0.2 | GO:0016578 | histone deubiquitination(GO:0016578) |
| 0.0 | 0.2 | GO:0043406 | positive regulation of MAP kinase activity(GO:0043406) |
| 0.0 | 0.1 | GO:0060766 | negative regulation of androgen receptor signaling pathway(GO:0060766) |
| 0.0 | 0.7 | GO:0061025 | membrane fusion(GO:0061025) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 1.4 | GO:0032591 | dendritic spine membrane(GO:0032591) |
| 0.4 | 1.6 | GO:0045257 | mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283) |
| 0.2 | 3.2 | GO:0005762 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
| 0.2 | 3.0 | GO:0005833 | hemoglobin complex(GO:0005833) |
| 0.2 | 0.5 | GO:0051233 | spindle midzone(GO:0051233) |
| 0.2 | 0.6 | GO:0071818 | BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379) |
| 0.2 | 1.1 | GO:0070937 | CRD-mediated mRNA stability complex(GO:0070937) |
| 0.1 | 6.8 | GO:0000786 | nucleosome(GO:0000786) |
| 0.1 | 1.2 | GO:0043218 | compact myelin(GO:0043218) |
| 0.1 | 1.5 | GO:1903561 | extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561) |
| 0.1 | 0.4 | GO:0043159 | acrosomal matrix(GO:0043159) |
| 0.1 | 0.7 | GO:0045179 | apical cortex(GO:0045179) |
| 0.1 | 0.7 | GO:0019815 | immunoglobulin complex(GO:0019814) B cell receptor complex(GO:0019815) |
| 0.1 | 1.5 | GO:0031088 | platelet dense granule membrane(GO:0031088) |
| 0.1 | 1.0 | GO:0005766 | primary lysosome(GO:0005766) azurophil granule(GO:0042582) |
| 0.1 | 0.6 | GO:0005750 | mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275) |
| 0.1 | 0.3 | GO:0042629 | mast cell granule(GO:0042629) |
| 0.1 | 1.0 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
| 0.1 | 0.3 | GO:0045261 | proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261) |
| 0.1 | 0.3 | GO:0042827 | platelet dense granule(GO:0042827) |
| 0.1 | 0.3 | GO:0098563 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
| 0.1 | 2.1 | GO:0043198 | dendritic shaft(GO:0043198) |
| 0.1 | 0.5 | GO:0034363 | intermediate-density lipoprotein particle(GO:0034363) |
| 0.1 | 0.7 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
| 0.1 | 0.8 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
| 0.1 | 0.5 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
| 0.1 | 0.4 | GO:0005744 | mitochondrial inner membrane presequence translocase complex(GO:0005744) |
| 0.1 | 3.9 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 0.1 | 1.8 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.1 | 1.3 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
| 0.1 | 0.2 | GO:0000124 | SAGA complex(GO:0000124) |
| 0.1 | 0.5 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 0.1 | 0.6 | GO:0045263 | proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263) |
| 0.0 | 0.9 | GO:0046930 | pore complex(GO:0046930) |
| 0.0 | 0.7 | GO:0045120 | pronucleus(GO:0045120) |
| 0.0 | 1.2 | GO:0031519 | PcG protein complex(GO:0031519) |
| 0.0 | 0.2 | GO:0016533 | cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533) |
| 0.0 | 12.5 | GO:0005813 | centrosome(GO:0005813) |
| 0.0 | 0.3 | GO:0005954 | calcium- and calmodulin-dependent protein kinase complex(GO:0005954) |
| 0.0 | 0.3 | GO:0016272 | prefoldin complex(GO:0016272) |
| 0.0 | 0.9 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
| 0.0 | 0.4 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
| 0.0 | 0.2 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
| 0.0 | 0.4 | GO:0000791 | euchromatin(GO:0000791) |
| 0.0 | 1.1 | GO:0005761 | organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761) |
| 0.0 | 0.2 | GO:0030061 | mitochondrial crista(GO:0030061) |
| 0.0 | 3.8 | GO:0005741 | mitochondrial outer membrane(GO:0005741) |
| 0.0 | 0.5 | GO:0000783 | telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783) |
| 0.0 | 0.1 | GO:0005863 | striated muscle myosin thick filament(GO:0005863) |
| 0.0 | 0.6 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.0 | 0.5 | GO:0005921 | gap junction(GO:0005921) |
| 0.0 | 0.1 | GO:0032144 | 4-aminobutyrate transaminase complex(GO:0032144) |
| 0.0 | 0.3 | GO:0001917 | photoreceptor inner segment(GO:0001917) |
| 0.0 | 2.3 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
| 0.0 | 0.5 | GO:0045334 | clathrin-coated endocytic vesicle(GO:0045334) |
| 0.0 | 0.4 | GO:0016235 | aggresome(GO:0016235) |
| 0.0 | 0.1 | GO:0005642 | annulate lamellae(GO:0005642) |
| 0.0 | 5.5 | GO:0005759 | mitochondrial matrix(GO:0005759) |
| 0.0 | 0.1 | GO:0031305 | intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305) |
| 0.0 | 0.5 | GO:0005811 | lipid particle(GO:0005811) |
| 0.0 | 0.2 | GO:0008021 | synaptic vesicle(GO:0008021) exocytic vesicle(GO:0070382) |
| 0.0 | 0.1 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.0 | 0.3 | GO:0032982 | myosin filament(GO:0032982) |
| 0.0 | 0.0 | GO:0070069 | cytochrome complex(GO:0070069) |
| 0.0 | 0.2 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.0 | 0.1 | GO:0042597 | NMDA selective glutamate receptor complex(GO:0017146) outer membrane-bounded periplasmic space(GO:0030288) periplasmic space(GO:0042597) |
| 0.0 | 0.2 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
| 0.0 | 0.3 | GO:0031265 | CD95 death-inducing signaling complex(GO:0031265) |
| 0.0 | 0.1 | GO:0014731 | spectrin-associated cytoskeleton(GO:0014731) |
| 0.0 | 0.2 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
| 0.0 | 0.1 | GO:0033268 | node of Ranvier(GO:0033268) |
| 0.0 | 0.3 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
| 0.0 | 0.4 | GO:0044452 | nucleolar part(GO:0044452) |
| 0.0 | 0.1 | GO:0030897 | HOPS complex(GO:0030897) |
| 0.0 | 0.3 | GO:0055037 | recycling endosome(GO:0055037) |
| 0.0 | 0.5 | GO:0044665 | MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339) |
| 0.0 | 3.3 | GO:0031966 | mitochondrial membrane(GO:0031966) |
| 0.0 | 9.0 | GO:0005739 | mitochondrion(GO:0005739) |
| 0.0 | 1.2 | GO:0009898 | cytoplasmic side of plasma membrane(GO:0009898) cytoplasmic side of membrane(GO:0098562) |
| 0.0 | 0.5 | GO:0005902 | microvillus(GO:0005902) |
| 0.0 | 0.1 | GO:0042588 | zymogen granule(GO:0042588) |
| 0.0 | 0.5 | GO:0098636 | integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636) |
| 0.0 | 0.2 | GO:0016585 | obsolete chromatin remodeling complex(GO:0016585) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 2.6 | GO:0045155 | electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155) |
| 0.6 | 1.9 | GO:0015141 | thiosulfate transmembrane transporter activity(GO:0015117) succinate transmembrane transporter activity(GO:0015141) |
| 0.5 | 1.6 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
| 0.4 | 1.3 | GO:0004853 | uroporphyrinogen decarboxylase activity(GO:0004853) |
| 0.4 | 1.6 | GO:0000104 | succinate dehydrogenase activity(GO:0000104) |
| 0.4 | 1.5 | GO:0004998 | transferrin receptor activity(GO:0004998) |
| 0.4 | 1.9 | GO:0004111 | creatine kinase activity(GO:0004111) |
| 0.4 | 2.6 | GO:0030506 | ankyrin binding(GO:0030506) |
| 0.4 | 1.1 | GO:0000156 | phosphorelay response regulator activity(GO:0000156) |
| 0.3 | 1.0 | GO:0004917 | interleukin-4 receptor activity(GO:0004913) interleukin-7 receptor activity(GO:0004917) interleukin-2 binding(GO:0019976) |
| 0.3 | 1.0 | GO:0004769 | steroid delta-isomerase activity(GO:0004769) |
| 0.3 | 1.5 | GO:0005220 | inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220) |
| 0.3 | 1.8 | GO:0017050 | sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050) |
| 0.2 | 2.2 | GO:0016018 | cyclosporin A binding(GO:0016018) |
| 0.2 | 3.0 | GO:0005344 | oxygen transporter activity(GO:0005344) |
| 0.2 | 0.9 | GO:0004826 | phenylalanine-tRNA ligase activity(GO:0004826) |
| 0.2 | 1.0 | GO:0008486 | diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) |
| 0.2 | 0.6 | GO:0004609 | phosphatidylserine decarboxylase activity(GO:0004609) |
| 0.2 | 1.7 | GO:0019237 | centromeric DNA binding(GO:0019237) |
| 0.2 | 0.9 | GO:0034594 | phosphatidylinositol trisphosphate phosphatase activity(GO:0034594) |
| 0.2 | 1.1 | GO:0019855 | calcium channel inhibitor activity(GO:0019855) |
| 0.2 | 2.1 | GO:0016884 | carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884) |
| 0.2 | 0.6 | GO:0005324 | long-chain fatty acid transporter activity(GO:0005324) |
| 0.1 | 2.2 | GO:0000155 | phosphorelay sensor kinase activity(GO:0000155) |
| 0.1 | 0.5 | GO:0003951 | NAD+ kinase activity(GO:0003951) |
| 0.1 | 1.4 | GO:0030899 | calcium-dependent ATPase activity(GO:0030899) |
| 0.1 | 1.2 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
| 0.1 | 0.5 | GO:0042808 | obsolete neuronal Cdc2-like kinase binding(GO:0042808) |
| 0.1 | 0.4 | GO:0033867 | Fas-activated serine/threonine kinase activity(GO:0033867) |
| 0.1 | 0.4 | GO:0033743 | peptide-methionine (R)-S-oxide reductase activity(GO:0033743) |
| 0.1 | 1.0 | GO:0031852 | mu-type opioid receptor binding(GO:0031852) |
| 0.1 | 1.0 | GO:0003876 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
| 0.1 | 0.5 | GO:0042910 | xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910) |
| 0.1 | 1.0 | GO:1901567 | icosanoid binding(GO:0050542) icosatetraenoic acid binding(GO:0050543) arachidonic acid binding(GO:0050544) fatty acid derivative binding(GO:1901567) |
| 0.1 | 3.1 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
| 0.1 | 1.0 | GO:0004873 | asialoglycoprotein receptor activity(GO:0004873) |
| 0.1 | 0.5 | GO:0060230 | lipoprotein lipase activator activity(GO:0060230) |
| 0.1 | 1.0 | GO:0051400 | BH domain binding(GO:0051400) |
| 0.1 | 0.5 | GO:0004591 | oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591) |
| 0.1 | 0.4 | GO:0005026 | transforming growth factor beta receptor activity, type II(GO:0005026) |
| 0.1 | 0.3 | GO:0015386 | potassium:proton antiporter activity(GO:0015386) |
| 0.1 | 1.9 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.1 | 0.4 | GO:0042903 | tubulin deacetylase activity(GO:0042903) |
| 0.1 | 0.5 | GO:0070182 | DNA polymerase binding(GO:0070182) |
| 0.1 | 0.3 | GO:0004738 | pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739) |
| 0.1 | 0.2 | GO:0042610 | CD8 receptor binding(GO:0042610) |
| 0.1 | 0.2 | GO:0031877 | somatostatin receptor binding(GO:0031877) |
| 0.1 | 0.3 | GO:0016361 | activin receptor activity, type I(GO:0016361) |
| 0.1 | 0.7 | GO:0004499 | N,N-dimethylaniline monooxygenase activity(GO:0004499) |
| 0.1 | 0.2 | GO:0008386 | cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) |
| 0.1 | 0.3 | GO:0004517 | nitric-oxide synthase activity(GO:0004517) |
| 0.1 | 0.5 | GO:0004703 | G-protein coupled receptor kinase activity(GO:0004703) |
| 0.1 | 0.3 | GO:0034481 | chondroitin sulfotransferase activity(GO:0034481) |
| 0.1 | 0.3 | GO:0004052 | arachidonate 12-lipoxygenase activity(GO:0004052) |
| 0.1 | 0.2 | GO:0050429 | calcium-dependent phospholipase C activity(GO:0050429) |
| 0.1 | 1.6 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.1 | 0.3 | GO:0004461 | beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831) lactose synthase activity(GO:0004461) |
| 0.1 | 0.3 | GO:0004449 | isocitrate dehydrogenase (NAD+) activity(GO:0004449) |
| 0.1 | 0.3 | GO:0032810 | sterol response element binding(GO:0032810) |
| 0.1 | 0.3 | GO:0004723 | calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) |
| 0.1 | 0.2 | GO:0050692 | DBD domain binding(GO:0050692) |
| 0.1 | 0.2 | GO:0004476 | mannose-6-phosphate isomerase activity(GO:0004476) |
| 0.1 | 0.3 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
| 0.1 | 0.4 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
| 0.1 | 0.4 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
| 0.1 | 0.4 | GO:0004340 | glucokinase activity(GO:0004340) |
| 0.1 | 0.4 | GO:0001733 | galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694) |
| 0.1 | 0.3 | GO:0070568 | guanylyltransferase activity(GO:0070568) |
| 0.1 | 0.2 | GO:0016534 | cyclin-dependent protein kinase 5 activator activity(GO:0016534) |
| 0.1 | 0.8 | GO:0004887 | thyroid hormone receptor activity(GO:0004887) |
| 0.1 | 0.6 | GO:0015355 | secondary active monocarboxylate transmembrane transporter activity(GO:0015355) |
| 0.1 | 0.4 | GO:0003886 | DNA (cytosine-5-)-methyltransferase activity(GO:0003886) |
| 0.1 | 0.8 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
| 0.1 | 0.4 | GO:0016681 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
| 0.0 | 0.5 | GO:0008195 | phosphatidate phosphatase activity(GO:0008195) |
| 0.0 | 0.1 | GO:0004967 | glucagon receptor activity(GO:0004967) |
| 0.0 | 0.5 | GO:0009374 | biotin binding(GO:0009374) |
| 0.0 | 0.4 | GO:0016405 | CoA-ligase activity(GO:0016405) |
| 0.0 | 0.4 | GO:0017081 | chloride channel regulator activity(GO:0017081) |
| 0.0 | 0.1 | GO:0004771 | sterol esterase activity(GO:0004771) |
| 0.0 | 0.9 | GO:0004889 | acetylcholine-activated cation-selective channel activity(GO:0004889) |
| 0.0 | 0.8 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.0 | 1.1 | GO:0005520 | insulin-like growth factor binding(GO:0005520) |
| 0.0 | 0.4 | GO:0016861 | intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861) |
| 0.0 | 0.5 | GO:0017070 | U6 snRNA binding(GO:0017070) |
| 0.0 | 0.5 | GO:0008199 | ferric iron binding(GO:0008199) |
| 0.0 | 0.1 | GO:0004359 | glutaminase activity(GO:0004359) |
| 0.0 | 0.5 | GO:0030544 | Hsp70 protein binding(GO:0030544) |
| 0.0 | 0.2 | GO:0051766 | inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766) |
| 0.0 | 0.1 | GO:0003726 | double-stranded RNA adenosine deaminase activity(GO:0003726) |
| 0.0 | 0.4 | GO:0005030 | neurotrophin receptor activity(GO:0005030) |
| 0.0 | 0.8 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.0 | 0.4 | GO:0015450 | P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450) |
| 0.0 | 0.5 | GO:0019992 | diacylglycerol binding(GO:0019992) |
| 0.0 | 0.1 | GO:0008048 | calcium sensitive guanylate cyclase activator activity(GO:0008048) |
| 0.0 | 0.3 | GO:0051428 | peptide hormone receptor binding(GO:0051428) |
| 0.0 | 0.1 | GO:0017089 | glycolipid transporter activity(GO:0017089) |
| 0.0 | 0.2 | GO:0043499 | obsolete eukaryotic cell surface binding(GO:0043499) |
| 0.0 | 1.4 | GO:0019212 | phosphatase inhibitor activity(GO:0019212) |
| 0.0 | 0.5 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
| 0.0 | 0.4 | GO:0050998 | nitric-oxide synthase binding(GO:0050998) |
| 0.0 | 0.6 | GO:0004467 | long-chain fatty acid-CoA ligase activity(GO:0004467) |
| 0.0 | 0.1 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
| 0.0 | 0.8 | GO:0051087 | chaperone binding(GO:0051087) |
| 0.0 | 0.3 | GO:0060590 | ATPase regulator activity(GO:0060590) |
| 0.0 | 5.7 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.0 | 1.4 | GO:0003823 | antigen binding(GO:0003823) |
| 0.0 | 0.2 | GO:0005237 | inhibitory extracellular ligand-gated ion channel activity(GO:0005237) |
| 0.0 | 0.6 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
| 0.0 | 3.5 | GO:0004725 | protein tyrosine phosphatase activity(GO:0004725) |
| 0.0 | 0.1 | GO:0032145 | 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298) |
| 0.0 | 0.1 | GO:0004972 | NMDA glutamate receptor activity(GO:0004972) |
| 0.0 | 0.1 | GO:0004676 | 3-phosphoinositide-dependent protein kinase activity(GO:0004676) |
| 0.0 | 0.3 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
| 0.0 | 0.1 | GO:0004985 | opioid receptor activity(GO:0004985) |
| 0.0 | 1.1 | GO:0003899 | DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062) |
| 0.0 | 0.1 | GO:0005137 | interleukin-5 receptor binding(GO:0005137) |
| 0.0 | 0.5 | GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding(GO:0005546) |
| 0.0 | 0.5 | GO:0008483 | transaminase activity(GO:0008483) |
| 0.0 | 1.0 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
| 0.0 | 1.2 | GO:0042826 | histone deacetylase binding(GO:0042826) |
| 0.0 | 1.0 | GO:0032947 | protein complex scaffold(GO:0032947) |
| 0.0 | 0.5 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 0.0 | 0.3 | GO:0050431 | transforming growth factor beta binding(GO:0050431) |
| 0.0 | 0.9 | GO:0008009 | chemokine activity(GO:0008009) |
| 0.0 | 0.1 | GO:0004103 | choline kinase activity(GO:0004103) |
| 0.0 | 0.1 | GO:0008320 | protein transmembrane transporter activity(GO:0008320) |
| 0.0 | 0.5 | GO:0019903 | protein phosphatase binding(GO:0019903) |
| 0.0 | 0.1 | GO:0001727 | lipid kinase activity(GO:0001727) |
| 0.0 | 0.6 | GO:0016836 | hydro-lyase activity(GO:0016836) |
| 0.0 | 1.7 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.0 | 0.3 | GO:0000062 | fatty-acyl-CoA binding(GO:0000062) |
| 0.0 | 0.2 | GO:0004993 | G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589) |
| 0.0 | 0.2 | GO:0005243 | gap junction channel activity(GO:0005243) |
| 0.0 | 0.5 | GO:0051219 | phosphoprotein binding(GO:0051219) |
| 0.0 | 0.2 | GO:0016175 | superoxide-generating NADPH oxidase activity(GO:0016175) |
| 0.0 | 0.2 | GO:0005416 | sodium:amino acid symporter activity(GO:0005283) cation:amino acid symporter activity(GO:0005416) |
| 0.0 | 0.2 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 0.0 | 0.2 | GO:0004859 | phospholipase inhibitor activity(GO:0004859) |
| 0.0 | 0.7 | GO:0004857 | enzyme inhibitor activity(GO:0004857) |
| 0.0 | 0.2 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
| 0.0 | 0.2 | GO:0030332 | cyclin binding(GO:0030332) |
| 0.0 | 0.4 | GO:0008066 | glutamate receptor activity(GO:0008066) |
| 0.0 | 0.2 | GO:0000049 | tRNA binding(GO:0000049) |
| 0.0 | 1.1 | GO:0003705 | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705) |
| 0.0 | 0.8 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.0 | 0.1 | GO:0050661 | NADP binding(GO:0050661) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.2 | ST_WNT_CA2_CYCLIC_GMP_PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
| 0.1 | 1.5 | SA_PROGRAMMED_CELL_DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
| 0.1 | 1.0 | ST_INTERLEUKIN_4_PATHWAY | Interleukin 4 (IL-4) Pathway |
| 0.0 | 0.4 | SA_TRKA_RECEPTOR | The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth. |
| 0.0 | 1.8 | SIG_IL4RECEPTOR_IN_B_LYPHOCYTES | Genes related to IL4 rceptor signaling in B lymphocytes |
| 0.0 | 0.9 | SA_B_CELL_RECEPTOR_COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
| 0.0 | 0.2 | ST_GRANULE_CELL_SURVIVAL_PATHWAY | Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway. |
| 0.0 | 1.7 | SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES | Genes related to PIP3 signaling in cardiac myocytes |
| 0.0 | 0.3 | SA_FAS_SIGNALING | The TNF-type receptor Fas induces apoptosis on ligand binding. |
| 0.0 | 0.4 | SIG_CD40PATHWAYMAP | Genes related to CD40 signaling |
| 0.0 | 0.7 | ST_T_CELL_SIGNAL_TRANSDUCTION | T Cell Signal Transduction |
| 0.0 | 0.2 | SA_G1_AND_S_PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
