Motif ID: NRF1

Z-value: 3.328


Transcription factors associated with NRF1:

Gene SymbolEntrez IDGene Name
NRF1 ENSG00000106459.10 NRF1



Activity profile for motif NRF1.

activity profile for motif NRF1


Sorted Z-values histogram for motif NRF1

Sorted Z-values for motif NRF1



Network of associatons between targets according to the STRING database.



First level regulatory network of NRF1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_65029421 3.838 ENST00000541089.1
POLA2
polymerase (DNA directed), alpha 2, accessory subunit
chr1_+_91966384 3.551 ENST00000430031.2
ENST00000234626.6
CDC7

cell division cycle 7

chr6_-_41040195 3.525 ENST00000463088.1
ENST00000469104.1
ENST00000486443.1
OARD1


O-acyl-ADP-ribose deacylase 1


chr17_-_57970074 3.468 ENST00000346141.6
TUBD1
tubulin, delta 1
chr6_-_41040268 3.253 ENST00000373154.2
ENST00000244558.9
ENST00000464633.1
ENST00000424266.2
ENST00000479950.1
ENST00000482515.1
OARD1





O-acyl-ADP-ribose deacylase 1





chr1_+_91966656 3.248 ENST00000428239.1
ENST00000426137.1
CDC7

cell division cycle 7

chr21_-_33651324 3.132 ENST00000290130.3
MIS18A
MIS18 kinetochore protein A
chr6_+_135502408 2.769 ENST00000341911.5
ENST00000442647.2
ENST00000316528.8
MYB


v-myb avian myeloblastosis viral oncogene homolog


chr6_+_24403144 2.752 ENST00000274747.7
ENST00000543597.1
ENST00000535061.1
ENST00000378353.1
ENST00000378386.3
ENST00000443868.2
MRS2





MRS2 magnesium transporter





chr6_+_135502466 2.715 ENST00000367814.4
MYB
v-myb avian myeloblastosis viral oncogene homolog
chr1_+_182808474 2.705 ENST00000367549.3
DHX9
DEAH (Asp-Glu-Ala-His) box helicase 9
chr17_+_7210898 2.687 ENST00000572815.1
EIF5A
eukaryotic translation initiation factor 5A
chr5_+_162887556 2.661 ENST00000393915.4
ENST00000432118.2
ENST00000358715.3
HMMR


hyaluronan-mediated motility receptor (RHAMM)


chr2_+_70056762 2.651 ENST00000282570.3
GMCL1
germ cell-less, spermatogenesis associated 1
chr17_-_57970219 2.620 ENST00000394239.3
ENST00000539018.1
ENST00000340993.6
ENST00000325752.3
ENST00000590498.1
ENST00000592145.1
TUBD1





tubulin, delta 1





chr19_-_50432654 2.519 ENST00000596680.1
ENST00000594673.1
ENST00000597029.1
NUP62


nucleoporin 62kDa


chrX_-_52260199 2.499 ENST00000375600.1
XAGE1A
X antigen family, member 1A
chr13_+_50656307 2.475 ENST00000378180.4
DLEU1
deleted in lymphocytic leukemia 1 (non-protein coding)
chr19_-_50432711 2.437 ENST00000596011.1
ENST00000596022.1
ENST00000597295.1
ENST00000597723.1
ENST00000599788.1
ENST00000596217.1
ENST00000593652.1
ENST00000599567.1
ENST00000600935.1
IL4I1


NUP62





interleukin 4 induced 1


nucleoporin 62kDa





chr11_+_65029233 2.386 ENST00000265465.3
POLA2
polymerase (DNA directed), alpha 2, accessory subunit
chr5_-_218251 2.337 ENST00000296824.3
CCDC127
coiled-coil domain containing 127
chr16_+_88869621 2.277 ENST00000301019.4
CDT1
chromatin licensing and DNA replication factor 1
chr19_-_44259053 2.226 ENST00000601170.1
SMG9
SMG9 nonsense mediated mRNA decay factor
chrX_-_52260355 2.154 ENST00000375602.1
ENST00000399800.3
XAGE1A

X antigen family, member 1A

chr1_-_246670519 2.144 ENST00000388985.4
ENST00000490107.1
SMYD3

SET and MYND domain containing 3

chr6_-_31774714 2.054 ENST00000375661.5
LSM2
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr16_+_27214802 2.054 ENST00000380948.2
ENST00000286096.4
KDM8

lysine (K)-specific demethylase 8

chr22_+_50247449 2.038 ENST00000216268.5
ZBED4
zinc finger, BED-type containing 4
chr19_-_44259136 2.008 ENST00000270066.6
SMG9
SMG9 nonsense mediated mRNA decay factor
chr16_+_23847339 1.980 ENST00000303531.7
PRKCB
protein kinase C, beta
chr9_+_110045537 1.951 ENST00000358015.3
RAD23B
RAD23 homolog B (S. cerevisiae)
chrX_+_49216659 1.944 ENST00000415752.1
GAGE12I
G antigen 12I
chr16_+_84733575 1.921 ENST00000219473.7
ENST00000563892.1
ENST00000562283.1
ENST00000570191.1
ENST00000569038.1
ENST00000570053.1
USP10





ubiquitin specific peptidase 10





chr6_-_35888905 1.913 ENST00000510290.1
ENST00000423325.2
ENST00000373822.1
SRPK1


SRSF protein kinase 1


chr6_-_35888824 1.901 ENST00000361690.3
ENST00000512445.1
SRPK1

SRSF protein kinase 1

chr19_+_50432400 1.874 ENST00000423777.2
ENST00000600336.1
ENST00000597227.1
ATF5


activating transcription factor 5


chr19_-_55770311 1.835 ENST00000412770.2
PPP6R1
protein phosphatase 6, regulatory subunit 1
chrX_-_52533139 1.809 ENST00000374959.3
XAGE1D
X antigen family, member 1D
chr11_+_63706444 1.806 ENST00000377793.4
ENST00000456907.2
ENST00000539656.1
NAA40


N(alpha)-acetyltransferase 40, NatD catalytic subunit


chr1_+_167190066 1.796 ENST00000367866.2
ENST00000429375.2
ENST00000452019.1
ENST00000420254.3
ENST00000541643.3
POU2F1




POU class 2 homeobox 1




chr18_-_5296001 1.788 ENST00000357006.4
ZBTB14
zinc finger and BTB domain containing 14
chr6_+_27806319 1.783 ENST00000606613.1
ENST00000396980.3
HIST1H2BN

histone cluster 1, H2bn

chr22_-_21356375 1.742 ENST00000215742.4
ENST00000399133.2
THAP7

THAP domain containing 7

chrX_-_153707246 1.736 ENST00000407062.1
LAGE3
L antigen family, member 3
chr6_-_153304697 1.717 ENST00000367241.3
FBXO5
F-box protein 5
chr6_-_27114577 1.708 ENST00000356950.1
ENST00000396891.4
HIST1H2BK

histone cluster 1, H2bk

chr4_-_57301748 1.700 ENST00000264220.2
PPAT
phosphoribosyl pyrophosphate amidotransferase
chr16_+_23847267 1.687 ENST00000321728.7
PRKCB
protein kinase C, beta
chrX_+_49178536 1.680 ENST00000442437.2
GAGE12J
G antigen 12J
chr5_-_133561752 1.677 ENST00000481195.1
ENST00000519718.1
PPP2CA
CTD-2410N18.5
protein phosphatase 2, catalytic subunit, alpha isozyme
S-phase kinase-associated protein 1
chr14_+_39583427 1.670 ENST00000308317.6
ENST00000396249.2
ENST00000250379.8
ENST00000534684.2
ENST00000527381.1
GEMIN2




gem (nuclear organelle) associated protein 2




chr19_+_11071685 1.659 ENST00000541122.2
ENST00000589677.1
ENST00000444061.3
SMARCA4


SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4


chr4_-_120988229 1.641 ENST00000296509.6
MAD2L1
MAD2 mitotic arrest deficient-like 1 (yeast)
chr16_-_103572 1.633 ENST00000293860.5
POLR3K
polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa
chr8_+_21777159 1.627 ENST00000434536.1
ENST00000252512.9
XPO7

exportin 7

chr16_+_230435 1.605 ENST00000199708.2
HBQ1
hemoglobin, theta 1
chr19_-_5720123 1.599 ENST00000587365.1
ENST00000585374.1
ENST00000593119.1
LONP1


lon peptidase 1, mitochondrial


chr20_-_57617831 1.587 ENST00000371033.5
ENST00000355937.4
SLMO2

slowmo homolog 2 (Drosophila)

chrX_+_52238974 1.574 ENST00000375613.3
XAGE1B
X antigen family, member 1B
chr19_+_49588677 1.573 ENST00000598984.1
ENST00000598441.1
SNRNP70

small nuclear ribonucleoprotein 70kDa (U1)

chr19_-_2328572 1.567 ENST00000252622.10
LSM7
LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr8_-_117886955 1.564 ENST00000297338.2
RAD21
RAD21 homolog (S. pombe)
chr21_-_34144157 1.552 ENST00000331923.4
PAXBP1
PAX3 and PAX7 binding protein 1
chr10_-_58120996 1.539 ENST00000361148.6
ENST00000395405.1
ENST00000373944.3
ZWINT


ZW10 interacting kinetochore protein


chr5_+_112312416 1.532 ENST00000389063.2
DCP2
decapping mRNA 2
chrX_-_71458802 1.532 ENST00000373657.1
ENST00000334463.3
ERCC6L

excision repair cross-complementing rodent repair deficiency, complementation group 6-like

chr1_+_212208919 1.525 ENST00000366991.4
ENST00000542077.1
DTL

denticleless E3 ubiquitin protein ligase homolog (Drosophila)

chrX_-_52546033 1.523 ENST00000375567.3
XAGE1E
X antigen family, member 1E
chr16_+_31191431 1.520 ENST00000254108.7
ENST00000380244.3
ENST00000568685.1
FUS


fused in sarcoma


chr5_+_68389807 1.516 ENST00000380860.4
ENST00000504103.1
ENST00000502979.1
SLC30A5


solute carrier family 30 (zinc transporter), member 5


chr19_+_19303720 1.483 ENST00000392324.4
RFXANK
regulatory factor X-associated ankyrin-containing protein
chr6_-_26216872 1.481 ENST00000244601.3
HIST1H2BG
histone cluster 1, H2bg
chr6_+_42981922 1.470 ENST00000326974.4
ENST00000244670.8
KLHDC3

kelch domain containing 3

chr16_+_2255710 1.459 ENST00000397124.1
ENST00000565250.1
MLST8

MTOR associated protein, LST8 homolog (S. cerevisiae)

chr4_+_54243798 1.458 ENST00000337488.6
ENST00000358575.5
ENST00000507922.1
FIP1L1


factor interacting with PAPOLA and CPSF1


chr12_+_69753448 1.457 ENST00000247843.2
ENST00000548020.1
ENST00000549685.1
ENST00000552955.1
YEATS4



YEATS domain containing 4



chr4_+_54243862 1.456 ENST00000306932.6
FIP1L1
factor interacting with PAPOLA and CPSF1
chr1_-_40349106 1.454 ENST00000545233.1
ENST00000537440.1
ENST00000537223.1
ENST00000541099.1
ENST00000441669.2
ENST00000544981.1
ENST00000316891.5
ENST00000372818.1
TRIT1







tRNA isopentenyltransferase 1







chr16_+_2255841 1.442 ENST00000301725.7
MLST8
MTOR associated protein, LST8 homolog (S. cerevisiae)
chr19_+_19303572 1.435 ENST00000407360.3
ENST00000540981.1
RFXANK

regulatory factor X-associated ankyrin-containing protein

chr7_+_96747030 1.434 ENST00000360382.4
ACN9
ACN9 homolog (S. cerevisiae)
chr12_+_69080734 1.419 ENST00000378905.2
NUP107
nucleoporin 107kDa
chr18_-_12884259 1.411 ENST00000353319.4
ENST00000327283.3
PTPN2

protein tyrosine phosphatase, non-receptor type 2

chr1_+_16174280 1.387 ENST00000375759.3
SPEN
spen family transcriptional repressor
chrX_-_129299847 1.384 ENST00000319908.3
ENST00000287295.3
AIFM1

apoptosis-inducing factor, mitochondrion-associated, 1

chr19_-_50432782 1.368 ENST00000341114.3
ENST00000595948.1
ENST00000413454.1
ENST00000596437.1
IL4I1

NUP62

interleukin 4 induced 1

nucleoporin 62kDa

chr10_+_60028818 1.365 ENST00000333926.5
CISD1
CDGSH iron sulfur domain 1
chr6_+_26183958 1.362 ENST00000356530.3
HIST1H2BE
histone cluster 1, H2be
chr2_-_111435610 1.361 ENST00000447014.1
ENST00000420328.1
ENST00000535254.1
ENST00000409311.1
ENST00000302759.6
BUB1




BUB1 mitotic checkpoint serine/threonine kinase




chr12_+_109535373 1.351 ENST00000242576.2
UNG
uracil-DNA glycosylase
chrX_-_153707545 1.344 ENST00000357360.4
LAGE3
L antigen family, member 3
chr7_+_100026406 1.336 ENST00000414441.1
MEPCE
methylphosphate capping enzyme
chrX_+_52238810 1.327 ENST00000437949.2
ENST00000375616.1
XAGE1B

X antigen family, member 1B

chr19_-_56632592 1.325 ENST00000587279.1
ENST00000270459.3
ZNF787

zinc finger protein 787

chr7_-_154794763 1.314 ENST00000404141.1
PAXIP1
PAX interacting (with transcription-activation domain) protein 1
chr17_+_57970469 1.313 ENST00000443572.2
ENST00000406116.3
ENST00000225577.4
ENST00000393021.3
RPS6KB1



ribosomal protein S6 kinase, 70kDa, polypeptide 1



chr7_-_154794621 1.306 ENST00000419436.1
ENST00000397192.1
PAXIP1

PAX interacting (with transcription-activation domain) protein 1

chr19_+_17416457 1.303 ENST00000252602.1
MRPL34
mitochondrial ribosomal protein L34
chr20_+_57556263 1.300 ENST00000602795.1
ENST00000344018.3
NELFCD

negative elongation factor complex member C/D

chr11_+_108535752 1.297 ENST00000322536.3
DDX10
DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
chr6_-_39693111 1.294 ENST00000373215.3
ENST00000538893.1
ENST00000287152.7
ENST00000373216.3
KIF6



kinesin family member 6



chr16_+_2255178 1.293 ENST00000564088.1
ENST00000382450.4
ENST00000569417.1
MLST8


MTOR associated protein, LST8 homolog (S. cerevisiae)


chr8_+_61591337 1.289 ENST00000423902.2
CHD7
chromodomain helicase DNA binding protein 7
chr9_+_131580734 1.283 ENST00000372642.4
ENDOG
endonuclease G
chr12_-_57146095 1.271 ENST00000550770.1
ENST00000338193.6
PRIM1

primase, DNA, polypeptide 1 (49kDa)

chr4_+_128703295 1.266 ENST00000296464.4
ENST00000508549.1
HSPA4L

heat shock 70kDa protein 4-like

chr11_-_61582579 1.265 ENST00000539419.1
ENST00000545245.1
ENST00000545405.1
ENST00000542506.1
FADS1



fatty acid desaturase 1



chr6_+_135502501 1.262 ENST00000527615.1
ENST00000420123.2
ENST00000525369.1
ENST00000528774.1
ENST00000534121.1
ENST00000534044.1
ENST00000533624.1
MYB






v-myb avian myeloblastosis viral oncogene homolog






chr19_+_17416609 1.252 ENST00000602206.1
MRPL34
mitochondrial ribosomal protein L34
chr9_+_115142217 1.246 ENST00000398805.3
ENST00000398803.1
ENST00000262542.7
ENST00000539114.1
HSDL2



hydroxysteroid dehydrogenase like 2



chr3_+_43732362 1.241 ENST00000458276.2
ABHD5
abhydrolase domain containing 5
chr6_+_41040678 1.231 ENST00000341376.6
ENST00000353205.5
NFYA

nuclear transcription factor Y, alpha

chr6_+_26199737 1.222 ENST00000359985.1
HIST1H2BF
histone cluster 1, H2bf
chr7_+_26331541 1.217 ENST00000416246.1
ENST00000338523.4
ENST00000412416.1
SNX10


sorting nexin 10


chr2_+_264869 1.213 ENST00000272067.6
ENST00000272065.5
ENST00000407983.3
ACP1


acid phosphatase 1, soluble


chr19_+_531713 1.211 ENST00000215574.4
CDC34
cell division cycle 34
chr6_-_39197226 1.205 ENST00000359534.3
KCNK5
potassium channel, subfamily K, member 5
chr5_+_612387 1.205 ENST00000264935.5
ENST00000444221.1
CEP72

centrosomal protein 72kDa

chr7_+_107384579 1.199 ENST00000222597.2
ENST00000415884.2
CBLL1

Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase

chr10_+_88854926 1.199 ENST00000298784.1
ENST00000298786.4
FAM35A

family with sequence similarity 35, member A

chr14_-_102553371 1.198 ENST00000553585.1
ENST00000216281.8
HSP90AA1

heat shock protein 90kDa alpha (cytosolic), class A member 1

chr22_+_24129138 1.197 ENST00000417137.1
ENST00000344921.6
ENST00000263121.7
ENST00000407422.3
ENST00000407082.3
SMARCB1




SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1




chr3_-_196159268 1.194 ENST00000381887.3
ENST00000535858.1
ENST00000428095.1
ENST00000296328.4
UBXN7



UBX domain protein 7



chr22_+_21271714 1.188 ENST00000354336.3
CRKL
v-crk avian sarcoma virus CT10 oncogene homolog-like
chr21_+_45553484 1.188 ENST00000291577.6
ENST00000427803.2
C21orf33

chromosome 21 open reading frame 33

chr12_-_49961883 1.186 ENST00000553173.1
ENST00000550165.1
ENST00000546244.1
ENST00000343810.4
MCRS1



microspherule protein 1



chrX_-_129299638 1.181 ENST00000535724.1
ENST00000346424.2
AIFM1

apoptosis-inducing factor, mitochondrion-associated, 1

chrX_-_134305322 1.180 ENST00000276241.6
ENST00000344129.2
CXorf48

cancer/testis antigen 55

chr16_-_4401258 1.175 ENST00000577031.1
PAM16
presequence translocase-associated motor 16 homolog (S. cerevisiae)
chr7_-_148581251 1.166 ENST00000478654.1
ENST00000460911.1
ENST00000350995.2
EZH2


enhancer of zeste homolog 2 (Drosophila)


chr5_-_88179302 1.159 ENST00000504921.2
MEF2C
myocyte enhancer factor 2C
chr19_+_59055814 1.154 ENST00000594806.1
ENST00000253024.5
ENST00000341753.6
TRIM28


tripartite motif containing 28


chr16_+_2255447 1.144 ENST00000562352.1
ENST00000562479.1
ENST00000301724.10
MLST8


MTOR associated protein, LST8 homolog (S. cerevisiae)


chr1_+_3773825 1.144 ENST00000378209.3
ENST00000338895.3
ENST00000378212.2
ENST00000341385.3
DFFB



DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)



chr18_+_10526008 1.135 ENST00000542979.1
ENST00000322897.6
NAPG

N-ethylmaleimide-sensitive factor attachment protein, gamma

chr5_+_154238149 1.132 ENST00000519430.1
ENST00000520671.1
ENST00000521583.1
ENST00000518028.1
ENST00000519404.1
ENST00000519394.1
ENST00000518775.1
CNOT8






CCR4-NOT transcription complex, subunit 8






chr5_-_132073210 1.131 ENST00000378735.1
ENST00000378746.4
KIF3A

kinesin family member 3A

chr1_+_26560676 1.130 ENST00000451429.2
ENST00000252992.4
CEP85

centrosomal protein 85kDa

chr21_-_34143971 1.125 ENST00000290178.4
PAXBP1
PAX3 and PAX7 binding protein 1
chr19_+_44100544 1.122 ENST00000391965.2
ENST00000525771.1
ZNF576

zinc finger protein 576

chr21_-_34960930 1.113 ENST00000437395.1
DONSON
downstream neighbor of SON
chr9_-_124922021 1.109 ENST00000537618.1
ENST00000373768.3
NDUFA8

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa

chr11_+_65101225 1.107 ENST00000528416.1
ENST00000415073.2
ENST00000252268.4
DPF2


D4, zinc and double PHD fingers family 2


chr10_+_127512106 1.104 ENST00000278100.6
ENST00000299130.3
ENST00000368759.5
ENST00000429863.2
BCCIP



BRCA2 and CDKN1A interacting protein



chr19_+_39421556 1.096 ENST00000407800.2
ENST00000402029.3
MRPS12

mitochondrial ribosomal protein S12

chr1_-_45452240 1.096 ENST00000372183.3
ENST00000372182.4
ENST00000360403.2
EIF2B3


eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa


chr19_-_41903161 1.096 ENST00000602129.1
ENST00000593771.1
ENST00000596905.1
ENST00000221233.4
EXOSC5



exosome component 5



chr16_+_28565230 1.096 ENST00000317058.3
CCDC101
coiled-coil domain containing 101
chr19_+_532049 1.096 ENST00000606136.1
CDC34
cell division cycle 34
chr9_+_4985016 1.095 ENST00000539801.1
JAK2
Janus kinase 2
chr19_-_10676666 1.094 ENST00000539027.1
ENST00000543682.1
ENST00000361821.5
ENST00000312962.6
KRI1



KRI1 homolog (S. cerevisiae)



chr15_+_41786065 1.092 ENST00000260386.5
ITPKA
inositol-trisphosphate 3-kinase A
chr1_-_149814478 1.092 ENST00000369161.3
HIST2H2AA3
histone cluster 2, H2aa3
chr18_+_47901365 1.083 ENST00000285116.3
SKA1
spindle and kinetochore associated complex subunit 1
chr6_-_27100529 1.081 ENST00000607124.1
ENST00000339812.2
ENST00000541790.1
HIST1H2BJ


histone cluster 1, H2bj


chr3_-_150320937 1.081 ENST00000479209.1
SERP1
stress-associated endoplasmic reticulum protein 1
chr5_+_218356 1.077 ENST00000264932.6
ENST00000504309.1
ENST00000510361.1
SDHA


succinate dehydrogenase complex, subunit A, flavoprotein (Fp)


chr12_+_93771659 1.070 ENST00000337179.5
ENST00000415493.2
NUDT4

nudix (nucleoside diphosphate linked moiety X)-type motif 4

chr17_-_47755436 1.067 ENST00000505581.1
ENST00000514121.1
ENST00000393328.2
ENST00000509079.1
ENST00000393331.3
ENST00000347630.2
ENST00000504102.1
SPOP






speckle-type POZ protein






chr7_-_75115548 1.065 ENST00000453279.2
POM121C
POM121 transmembrane nucleoporin C
chr7_+_107384142 1.064 ENST00000440859.3
CBLL1
Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase
chr5_+_170814803 1.064 ENST00000521672.1
ENST00000351986.6
ENST00000393820.2
ENST00000523622.1
NPM1



nucleophosmin (nucleolar phosphoprotein B23, numatrin)



chr4_+_128702969 1.063 ENST00000508776.1
ENST00000439123.2
HSPA4L

heat shock 70kDa protein 4-like

chr10_-_70231639 1.062 ENST00000551118.2
ENST00000358410.3
ENST00000399180.2
ENST00000399179.2
DNA2



DNA replication helicase/nuclease 2



chr19_+_44100727 1.059 ENST00000528387.1
ENST00000529930.1
ENST00000336564.4
ENST00000607544.1
ENST00000526798.1
ZNF576


SRRM5

zinc finger protein 576


serine/arginine repetitive matrix 5

chr6_+_26124373 1.056 ENST00000377791.2
ENST00000602637.1
HIST1H2AC

histone cluster 1, H2ac

chr1_-_21948906 1.055 ENST00000374761.2
ENST00000599760.1
RAP1GAP

RAP1 GTPase activating protein

chr21_-_34960948 1.052 ENST00000453626.1
ENST00000303113.6
ENST00000432378.1
ENST00000303071.5
DONSON



downstream neighbor of SON



chr3_+_44379944 1.050 ENST00000396078.3
ENST00000342649.4
TCAIM

T cell activation inhibitor, mitochondrial

chr7_-_124569991 1.048 ENST00000446993.1
ENST00000357628.3
ENST00000393329.1
POT1


protection of telomeres 1


chr19_+_39109735 1.046 ENST00000593149.1
ENST00000248342.4
ENST00000538434.1
ENST00000588934.1
ENST00000545173.2
ENST00000589307.1
ENST00000586513.1
ENST00000591409.1
ENST00000592558.1
EIF3K








eukaryotic translation initiation factor 3, subunit K








chr6_-_26124138 1.042 ENST00000314332.5
ENST00000396984.1
HIST1H2BC

histone cluster 1, H2bc

chr6_-_136610911 1.034 ENST00000530767.1
ENST00000527759.1
ENST00000527536.1
ENST00000529826.1
ENST00000531224.1
ENST00000353331.4
BCLAF1





BCL2-associated transcription factor 1





chr6_+_27100811 1.032 ENST00000359193.2
HIST1H2AG
histone cluster 1, H2ag
chrX_-_153847522 1.026 ENST00000328435.2
ENST00000359887.4
CTAG1B

cancer/testis antigen 1B

chr5_-_96518907 1.023 ENST00000508447.1
ENST00000283109.3
RIOK2

RIO kinase 2

chr1_+_174969262 1.018 ENST00000406752.1
ENST00000405362.1
CACYBP

calcyclin binding protein

chr9_+_108456800 1.016 ENST00000434214.1
ENST00000374692.3
TMEM38B

transmembrane protein 38B

chr20_-_35402123 1.014 ENST00000373740.3
ENST00000426836.1
ENST00000373745.3
ENST00000448110.2
ENST00000438549.1
ENST00000447406.1
ENST00000373750.4
ENST00000373734.4
DSN1







DSN1, MIS12 kinetochore complex component







chr19_+_47634039 1.008 ENST00000597808.1
ENST00000413379.3
ENST00000600706.1
ENST00000540850.1
ENST00000598840.1
ENST00000600753.1
ENST00000270225.7
ENST00000392776.3
SAE1







SUMO1 activating enzyme subunit 1







chr5_+_102455968 1.003 ENST00000358359.3
PPIP5K2
diphosphoinositol pentakisphosphate kinase 2
chr1_-_29508321 0.998 ENST00000546138.1
SRSF4
serine/arginine-rich splicing factor 4
chr7_-_148581360 0.997 ENST00000320356.2
ENST00000541220.1
ENST00000483967.1
ENST00000536783.1
EZH2



enhancer of zeste homolog 2 (Drosophila)



chr1_-_1709845 0.996 ENST00000341426.5
ENST00000344463.4
NADK

NAD kinase

chr21_+_45553535 0.994 ENST00000348499.5
ENST00000389690.3
ENST00000449622.1
C21orf33


chromosome 21 open reading frame 33


chr5_+_61602055 0.994 ENST00000381103.2
KIF2A
kinesin heavy chain member 2A
chr4_+_17812525 0.992 ENST00000251496.2
NCAPG
non-SMC condensin I complex, subunit G
chr1_-_212208842 0.990 ENST00000366992.3
ENST00000366993.3
ENST00000440600.2
ENST00000366994.3
INTS7



integrator complex subunit 7



chr22_-_43583079 0.983 ENST00000216129.6
TTLL12
tubulin tyrosine ligase-like family, member 12
chr2_-_27357479 0.983 ENST00000406567.3
ENST00000260643.2
PREB

prolactin regulatory element binding

chr6_+_26217159 0.978 ENST00000303910.2
HIST1H2AE
histone cluster 1, H2ae
chr10_-_73976025 0.971 ENST00000342444.4
ENST00000533958.1
ENST00000527593.1
ENST00000394915.3
ENST00000530461.1
ENST00000317168.6
ENST00000524829.1
ASCC1






activating signal cointegrator 1 complex subunit 1






chr19_+_11071652 0.966 ENST00000344626.4
ENST00000429416.3
SMARCA4

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4

chr20_-_35580240 0.964 ENST00000262878.4
SAMHD1
SAM domain and HD domain 1
chr5_-_175815565 0.957 ENST00000509257.1
ENST00000507413.1
ENST00000510123.1
NOP16


NOP16 nucleolar protein


chr7_+_142985308 0.955 ENST00000310447.5
CASP2
caspase 2, apoptosis-related cysteine peptidase
chr17_+_80416050 0.954 ENST00000579198.1
ENST00000390006.4
ENST00000580296.1
NARF


nuclear prelamin A recognition factor


chr4_-_2243839 0.954 ENST00000511885.2
ENST00000506763.1
ENST00000514395.1
ENST00000502440.1
ENST00000243706.4
ENST00000443786.2
POLN
HAUS3




polymerase (DNA directed) nu
HAUS augmin-like complex, subunit 3




chr10_-_73975657 0.953 ENST00000394919.1
ENST00000526751.1
ASCC1

activating signal cointegrator 1 complex subunit 1

chr17_+_80416482 0.951 ENST00000309794.11
ENST00000345415.7
ENST00000457415.3
ENST00000584411.1
ENST00000412079.2
ENST00000577432.1
NARF





nuclear prelamin A recognition factor






Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.9 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.9 2.6 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.8 2.3 GO:0070407 oxidation-dependent protein catabolic process(GO:0070407)
0.7 5.5 GO:0060766 negative regulation of androgen receptor signaling pathway(GO:0060766)
0.7 8.3 GO:0033261 obsolete regulation of S phase(GO:0033261)
0.7 2.1 GO:0051255 spindle midzone assembly(GO:0051255) meiotic spindle midzone assembly(GO:0051257)
0.7 2.6 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.6 3.0 GO:0071168 protein localization to chromatin(GO:0071168)
0.6 2.2 GO:0000212 meiotic spindle organization(GO:0000212)
0.5 1.1 GO:0006273 lagging strand elongation(GO:0006273)
0.5 2.1 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.5 2.6 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.5 1.5 GO:0016926 protein desumoylation(GO:0016926)
0.5 1.9 GO:0090267 positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.5 4.3 GO:0007090 obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.5 1.4 GO:0010041 response to iron(III) ion(GO:0010041) positive regulation of histone phosphorylation(GO:0033129) response to DDT(GO:0046680) regulation of chromosome condensation(GO:0060623) cellular response to iron ion(GO:0071281) cellular response to iron(III) ion(GO:0071283)
0.5 1.8 GO:0007262 STAT protein import into nucleus(GO:0007262) regulation of growth hormone receptor signaling pathway(GO:0060398)
0.5 1.8 GO:0010520 regulation of reciprocal meiotic recombination(GO:0010520) intra-S DNA damage checkpoint(GO:0031573) negative regulation of meiotic nuclear division(GO:0045835) regulation of meiosis I(GO:0060631)
0.4 1.3 GO:1990170 detoxification of cadmium ion(GO:0071585) stress response to cadmium ion(GO:1990170)
0.4 1.3 GO:0014889 response to stimulus involved in regulation of muscle adaptation(GO:0014874) muscle atrophy(GO:0014889) regulation of skeletal muscle tissue growth(GO:0048631)
0.4 1.3 GO:0007109 obsolete cytokinesis, completion of separation(GO:0007109) protein hexamerization(GO:0034214)
0.4 1.3 GO:0051645 Golgi localization(GO:0051645)
0.4 2.5 GO:0019985 translesion synthesis(GO:0019985)
0.4 1.2 GO:1904742 regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381) regulation of telomeric DNA binding(GO:1904742) positive regulation of telomeric DNA binding(GO:1904744)
0.4 2.0 GO:0010826 negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.4 3.2 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.4 1.6 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.4 7.8 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.4 2.7 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.4 1.2 GO:0030091 protein repair(GO:0030091)
0.4 1.5 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.4 1.1 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.4 6.4 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) positive regulation of ERBB signaling pathway(GO:1901186)
0.3 3.0 GO:0006020 inositol metabolic process(GO:0006020)
0.3 5.4 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.3 2.3 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.3 2.3 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.3 1.3 GO:0016233 telomere capping(GO:0016233)
0.3 1.0 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
0.3 1.3 GO:0040016 embryonic cleavage(GO:0040016)
0.3 1.2 GO:0072076 nephrogenic mesenchyme development(GO:0072076) nephrogenic mesenchyme morphogenesis(GO:0072134)
0.3 2.1 GO:0045040 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.3 1.2 GO:0034629 cellular protein complex localization(GO:0034629)
0.3 1.8 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.3 0.6 GO:0046015 carbon catabolite regulation of transcription(GO:0045990) regulation of transcription by glucose(GO:0046015)
0.3 1.2 GO:0060025 regulation of synaptic activity(GO:0060025)
0.3 0.8 GO:0070671 response to interleukin-12(GO:0070671)
0.3 2.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.3 2.4 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.3 1.3 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.3 0.8 GO:0034139 regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.3 0.8 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003)
0.3 1.3 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.3 6.0 GO:0031055 DNA replication-independent nucleosome assembly(GO:0006336) chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) DNA replication-independent nucleosome organization(GO:0034724) CENP-A containing chromatin organization(GO:0061641)
0.3 4.7 GO:0006386 transcription elongation from RNA polymerase III promoter(GO:0006385) termination of RNA polymerase III transcription(GO:0006386)
0.3 1.6 GO:0006999 nuclear pore organization(GO:0006999)
0.3 0.8 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.3 0.8 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.3 6.1 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.3 1.5 GO:0042518 negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.3 0.3 GO:0071025 RNA surveillance(GO:0071025) nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.3 0.8 GO:0031297 replication fork processing(GO:0031297) DNA-dependent DNA replication maintenance of fidelity(GO:0045005)
0.2 1.7 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.2 0.5 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.2 2.2 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.2 1.4 GO:0071459 protein localization to kinetochore(GO:0034501) protein localization to chromosome, centromeric region(GO:0071459)
0.2 1.2 GO:0060017 parathyroid gland development(GO:0060017)
0.2 1.6 GO:0015853 adenine transport(GO:0015853)
0.2 1.9 GO:0048712 negative regulation of astrocyte differentiation(GO:0048712)
0.2 0.7 GO:0071104 response to interleukin-9(GO:0071104) response to interleukin-11(GO:0071105)
0.2 1.6 GO:0015671 oxygen transport(GO:0015671)
0.2 2.3 GO:0016180 snRNA processing(GO:0016180)
0.2 1.6 GO:0044818 mitotic G2/M transition checkpoint(GO:0044818)
0.2 2.5 GO:0060123 regulation of growth hormone secretion(GO:0060123)
0.2 0.7 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.2 1.1 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.2 0.9 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.2 0.9 GO:0009103 lipopolysaccharide biosynthetic process(GO:0009103)
0.2 0.9 GO:0071218 cellular response to misfolded protein(GO:0071218)
0.2 0.9 GO:0000491 small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.2 0.8 GO:0000394 RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394) tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.2 0.8 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.2 2.3 GO:0009113 purine nucleobase biosynthetic process(GO:0009113)
0.2 2.9 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.2 0.6 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.2 1.0 GO:0016925 protein sumoylation(GO:0016925)
0.2 1.4 GO:0090400 stress-induced premature senescence(GO:0090400)
0.2 0.6 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.2 0.8 GO:0033197 response to vitamin E(GO:0033197)
0.2 2.4 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.2 1.4 GO:0043457 regulation of cellular respiration(GO:0043457)
0.2 1.4 GO:0007063 regulation of sister chromatid cohesion(GO:0007063)
0.2 1.5 GO:0045008 depyrimidination(GO:0045008)
0.2 13.8 GO:0006334 nucleosome assembly(GO:0006334)
0.2 0.8 GO:0009106 lipoate metabolic process(GO:0009106)
0.2 2.8 GO:0000090 mitotic anaphase(GO:0000090)
0.2 0.6 GO:0031167 rRNA methylation(GO:0031167)
0.2 0.7 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934)
0.2 0.6 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.2 0.7 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.2 1.4 GO:0046831 regulation of RNA export from nucleus(GO:0046831)
0.2 1.1 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.2 0.5 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.2 1.2 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.2 3.3 GO:0043968 histone H2A acetylation(GO:0043968)
0.2 5.4 GO:0050684 regulation of mRNA processing(GO:0050684) regulation of mRNA metabolic process(GO:1903311)
0.2 0.7 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.2 2.7 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.2 1.3 GO:0006312 mitotic recombination(GO:0006312)
0.2 1.3 GO:0002566 somatic diversification of immune receptors via somatic mutation(GO:0002566) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.2 0.5 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.2 0.8 GO:0010508 positive regulation of autophagy(GO:0010508)
0.2 0.7 GO:0033522 histone H2A ubiquitination(GO:0033522)
0.2 0.8 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.2 2.0 GO:0044349 nucleotide-excision repair, DNA damage removal(GO:0000718) DNA excision(GO:0044349)
0.2 0.8 GO:0046607 positive regulation of centrosome cycle(GO:0046607)
0.2 0.3 GO:0043558 regulation of translational initiation in response to stress(GO:0043558)
0.1 1.2 GO:0039703 single stranded viral RNA replication via double stranded DNA intermediate(GO:0039692) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.1 1.8 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.1 0.4 GO:0071344 diphosphate metabolic process(GO:0071344)
0.1 1.3 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.1 1.6 GO:0055069 cellular zinc ion homeostasis(GO:0006882) zinc ion homeostasis(GO:0055069)
0.1 0.9 GO:0006449 regulation of translational termination(GO:0006449)
0.1 0.4 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1 2.3 GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.1 0.9 GO:0019372 lipoxygenase pathway(GO:0019372)
0.1 2.0 GO:0006105 succinate metabolic process(GO:0006105)
0.1 1.1 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.1 1.1 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.1 0.7 GO:0051790 short-chain fatty acid biosynthetic process(GO:0051790)
0.1 0.4 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.1 6.9 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.1 0.4 GO:0006344 maintenance of chromatin silencing(GO:0006344) hair follicle placode formation(GO:0060789) fungiform papilla development(GO:0061196) fungiform papilla morphogenesis(GO:0061197) fungiform papilla formation(GO:0061198)
0.1 1.1 GO:0061101 neuroendocrine cell differentiation(GO:0061101)
0.1 0.4 GO:0071428 rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.1 0.5 GO:0030261 chromosome condensation(GO:0030261)
0.1 8.3 GO:0008033 tRNA processing(GO:0008033)
0.1 0.5 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.1 1.0 GO:0000959 mitochondrial RNA metabolic process(GO:0000959) transcription from mitochondrial promoter(GO:0006390)
0.1 3.6 GO:0060334 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.1 0.6 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.1 1.0 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.1 3.9 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 0.4 GO:0021896 forebrain astrocyte differentiation(GO:0021896) forebrain astrocyte development(GO:0021897)
0.1 0.4 GO:0034442 plasma lipoprotein particle oxidation(GO:0034441) regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) lipoprotein modification(GO:0042160) lipoprotein oxidation(GO:0042161)
0.1 0.2 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.1 0.2 GO:0042775 ATP synthesis coupled electron transport(GO:0042773) mitochondrial ATP synthesis coupled electron transport(GO:0042775)
0.1 1.2 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.1 0.5 GO:0032506 cytokinetic process(GO:0032506)
0.1 0.8 GO:0001522 pseudouridine synthesis(GO:0001522)
0.1 1.0 GO:0001554 luteolysis(GO:0001554)
0.1 0.4 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.1 0.9 GO:0051567 histone H3-K9 methylation(GO:0051567) histone H3-K9 modification(GO:0061647)
0.1 1.3 GO:0009744 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.1 3.8 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.1 0.2 GO:0031062 positive regulation of histone methylation(GO:0031062) positive regulation of histone H3-K4 methylation(GO:0051571)
0.1 0.4 GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000466)
0.1 0.2 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.1 1.6 GO:0016578 histone deubiquitination(GO:0016578)
0.1 0.6 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1 0.4 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.1 2.9 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.1 0.3 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.1 0.1 GO:0002456 T cell mediated immunity(GO:0002456)
0.1 0.3 GO:0018283 metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283)
0.1 2.0 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 0.3 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1 0.6 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.1 0.6 GO:0031958 corticosteroid receptor signaling pathway(GO:0031958)
0.1 0.5 GO:0003070 age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070)
0.1 4.7 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 0.5 GO:0051383 kinetochore assembly(GO:0051382) kinetochore organization(GO:0051383)
0.1 0.7 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.1 0.4 GO:0051103 DNA ligation involved in DNA repair(GO:0051103)
0.1 0.3 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.1 0.5 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.1 0.7 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 0.6 GO:0046498 S-adenosylhomocysteine metabolic process(GO:0046498)
0.1 0.2 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1 0.6 GO:0010815 bradykinin catabolic process(GO:0010815)
0.1 0.7 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.1 1.8 GO:0051703 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.1 2.9 GO:0034470 ncRNA processing(GO:0034470)
0.1 0.5 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.1 0.6 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 0.2 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.1 0.2 GO:0021513 spinal cord dorsal/ventral patterning(GO:0021513)
0.1 2.2 GO:0006490 dolichol-linked oligosaccharide biosynthetic process(GO:0006488) oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.1 2.0 GO:0034968 histone lysine methylation(GO:0034968)
0.1 0.7 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 0.4 GO:0060676 ureteric bud formation(GO:0060676) mesonephric tubule formation(GO:0072172)
0.1 2.2 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.1 2.6 GO:0033572 ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.1 1.7 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.1 0.3 GO:0015693 magnesium ion transport(GO:0015693)
0.1 0.3 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.1 0.4 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.1 0.4 GO:0098927 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.1 0.2 GO:0070781 response to biotin(GO:0070781)
0.1 1.5 GO:0006825 copper ion transport(GO:0006825)
0.1 3.5 GO:0007051 spindle organization(GO:0007051)
0.1 2.2 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.1 2.5 GO:0006903 vesicle targeting(GO:0006903)
0.1 0.3 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 1.2 GO:0006284 base-excision repair(GO:0006284)
0.1 0.3 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.1 0.3 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.1 0.8 GO:0071479 cellular response to ionizing radiation(GO:0071479)
0.1 0.7 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.1 1.3 GO:0043278 response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.1 3.3 GO:0051028 mRNA transport(GO:0051028)
0.1 0.2 GO:0021819 cerebral cortex radial glia guided migration(GO:0021801) layer formation in cerebral cortex(GO:0021819) telencephalon glial cell migration(GO:0022030)
0.1 7.0 GO:0007018 microtubule-based movement(GO:0007018)
0.1 0.2 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.1 0.2 GO:0009451 RNA modification(GO:0009451)
0.1 0.9 GO:0007020 microtubule nucleation(GO:0007020)
0.1 0.3 GO:0009143 nucleoside triphosphate catabolic process(GO:0009143)
0.1 1.0 GO:0006111 regulation of gluconeogenesis(GO:0006111)
0.1 0.2 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.1 0.3 GO:0042984 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.1 0.2 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 0.8 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 0.7 GO:0043330 response to exogenous dsRNA(GO:0043330)
0.1 0.3 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 0.5 GO:1904031 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.1 0.7 GO:0032456 endocytic recycling(GO:0032456)
0.1 0.3 GO:0018343 protein farnesylation(GO:0018343)
0.1 0.3 GO:0043084 penile erection(GO:0043084)
0.1 0.3 GO:0032527 retrograde protein transport, ER to cytosol(GO:0030970) protein exit from endoplasmic reticulum(GO:0032527)
0.1 1.2 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.1 0.4 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.1 1.1 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.1 0.6 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.1 0.3 GO:0031274 pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.1 0.3 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090)
0.1 0.7 GO:0006743 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744)
0.1 0.2 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.4 GO:0016571 histone methylation(GO:0016571)
0.0 1.0 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.3 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.1 GO:0031033 myosin filament organization(GO:0031033)
0.0 3.1 GO:0006986 response to unfolded protein(GO:0006986)
0.0 0.1 GO:0072148 epithelial cell fate commitment(GO:0072148)
0.0 1.3 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.1 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0 0.2 GO:0045896 regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.0 0.1 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.3 GO:0045176 apical protein localization(GO:0045176)
0.0 0.2 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.0 0.4 GO:0051319 mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0 0.2 GO:0045350 interferon-beta biosynthetic process(GO:0045350) regulation of interferon-beta biosynthetic process(GO:0045357) positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.0 0.2 GO:0006893 Golgi to plasma membrane transport(GO:0006893) vesicle-mediated transport to the plasma membrane(GO:0098876)
0.0 1.4 GO:0050999 regulation of nitric-oxide synthase activity(GO:0050999)
0.0 0.2 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037) actin filament reorganization(GO:0090527)
0.0 13.1 GO:0006397 mRNA processing(GO:0006397)
0.0 0.3 GO:0051223 regulation of protein transport(GO:0051223)
0.0 1.2 GO:0019674 NAD metabolic process(GO:0019674)
0.0 2.2 GO:0006302 double-strand break repair(GO:0006302)
0.0 0.2 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.2 GO:0032608 interferon-beta production(GO:0032608) regulation of interferon-beta production(GO:0032648)
0.0 0.1 GO:0032328 alanine transport(GO:0032328)
0.0 0.5 GO:0031053 primary miRNA processing(GO:0031053)
0.0 1.2 GO:0006626 protein targeting to mitochondrion(GO:0006626)
0.0 2.4 GO:0006413 translational initiation(GO:0006413)
0.0 1.7 GO:0070646 protein modification by small protein removal(GO:0070646)
0.0 0.9 GO:0001702 gastrulation with mouth forming second(GO:0001702)
0.0 0.1 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.0 0.1 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)
0.0 0.2 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0 0.3 GO:0031670 cellular response to nutrient(GO:0031670)
0.0 0.2 GO:0045116 protein neddylation(GO:0045116)
0.0 1.3 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.0 0.6 GO:0001662 behavioral fear response(GO:0001662)
0.0 0.3 GO:0060390 regulation of SMAD protein import into nucleus(GO:0060390) positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.6 GO:0042274 ribosomal small subunit biogenesis(GO:0042274)
0.0 0.3 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.7 GO:0045814 negative regulation of gene expression, epigenetic(GO:0045814)
0.0 0.4 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0 0.7 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.1 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.1 GO:0071679 facial nucleus development(GO:0021754) cell proliferation in midbrain(GO:0033278) commissural neuron axon guidance(GO:0071679)
0.0 0.5 GO:0042359 vitamin D metabolic process(GO:0042359)
0.0 0.5 GO:0071333 cellular response to monosaccharide stimulus(GO:0071326) cellular response to hexose stimulus(GO:0071331) cellular response to glucose stimulus(GO:0071333)
0.0 0.2 GO:0043545 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0 0.1 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307) DNA dealkylation(GO:0035510)
0.0 0.6 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.2 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 2.6 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
0.0 0.3 GO:0015074 DNA integration(GO:0015074)
0.0 1.7 GO:0006333 chromatin assembly or disassembly(GO:0006333)
0.0 0.4 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.2 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.2 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.0 0.9 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.0 0.6 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.0 0.1 GO:0045075 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0 0.2 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.0 0.7 GO:0051289 protein homotetramerization(GO:0051289)
0.0 0.1 GO:0042339 keratan sulfate metabolic process(GO:0042339)
0.0 0.4 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.9 GO:0051320 mitotic S phase(GO:0000084) S phase(GO:0051320)
0.0 0.5 GO:0043101 purine-containing compound salvage(GO:0043101)
0.0 0.8 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.7 GO:0009067 aspartate family amino acid biosynthetic process(GO:0009067)
0.0 1.4 GO:0006094 gluconeogenesis(GO:0006094)
0.0 0.3 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.0 0.2 GO:0010288 response to lead ion(GO:0010288)
0.0 0.3 GO:0051329 mitotic interphase(GO:0051329)
0.0 0.1 GO:0006528 asparagine metabolic process(GO:0006528)
0.0 0.1 GO:0045056 transcytosis(GO:0045056)
0.0 0.1 GO:0060736 prostate gland growth(GO:0060736)
0.0 0.5 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.1 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.1 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0 0.0 GO:0040019 positive regulation of embryonic development(GO:0040019)
0.0 0.2 GO:0045060 negative T cell selection(GO:0043383) negative thymic T cell selection(GO:0045060)
0.0 0.2 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.5 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.4 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.4 GO:0048246 macrophage chemotaxis(GO:0048246)
0.0 0.4 GO:0006200 obsolete ATP catabolic process(GO:0006200)
0.0 0.2 GO:0006305 DNA alkylation(GO:0006305) DNA methylation(GO:0006306) DNA methylation or demethylation(GO:0044728)
0.0 0.1 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.1 GO:0007289 spermatid nucleus differentiation(GO:0007289)
0.0 0.6 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.2 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.6 GO:0001837 epithelial to mesenchymal transition(GO:0001837)
0.0 0.1 GO:0031047 gene silencing by RNA(GO:0031047)
0.0 0.5 GO:0009880 embryonic pattern specification(GO:0009880)
0.0 0.4 GO:0001756 somitogenesis(GO:0001756) somite development(GO:0061053)
0.0 0.2 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.2 GO:0007131 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.0 0.5 GO:0006354 DNA-templated transcription, elongation(GO:0006354)
0.0 1.3 GO:0006352 DNA-templated transcription, initiation(GO:0006352)
0.0 0.0 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.0 0.5 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.2 GO:0046686 response to cadmium ion(GO:0046686)
0.0 0.5 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 0.3 GO:0048747 muscle fiber development(GO:0048747)
0.0 0.3 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 1.2 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.6 GO:0006096 glycolytic process(GO:0006096) ATP generation from ADP(GO:0006757)
0.0 0.5 GO:1903046 meiotic cell cycle(GO:0051321) meiotic cell cycle process(GO:1903046)
0.0 0.1 GO:0046632 alpha-beta T cell differentiation(GO:0046632)
0.0 0.8 GO:0050870 positive regulation of homotypic cell-cell adhesion(GO:0034112) positive regulation of T cell activation(GO:0050870) positive regulation of leukocyte cell-cell adhesion(GO:1903039)
0.0 0.4 GO:0051925 obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.0 0.0 GO:0046469 platelet activating factor biosynthetic process(GO:0006663) platelet activating factor metabolic process(GO:0046469)
0.0 0.2 GO:0019221 cytokine-mediated signaling pathway(GO:0019221)
0.0 0.2 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.0 0.8 GO:0034339 obsolete regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor(GO:0034339)
0.0 0.3 GO:0034035 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.0 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.0 0.3 GO:0048659 smooth muscle cell proliferation(GO:0048659)
0.0 0.1 GO:0007032 endosome organization(GO:0007032)
0.0 0.2 GO:0048167 regulation of synaptic plasticity(GO:0048167)
0.0 0.1 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.0 GO:0006983 ER overload response(GO:0006983)
0.0 0.1 GO:0051602 response to electrical stimulus(GO:0051602)
0.0 0.3 GO:0030177 positive regulation of Wnt signaling pathway(GO:0030177)
0.0 0.2 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 0.2 GO:0030593 neutrophil chemotaxis(GO:0030593) neutrophil migration(GO:1990266)
0.0 0.1 GO:0000209 protein polyubiquitination(GO:0000209)
0.0 2.7 GO:0000122 negative regulation of transcription from RNA polymerase II promoter(GO:0000122)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 6.3 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
1.5 8.9 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.8 2.4 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.6 1.8 GO:0032302 MutSbeta complex(GO:0032302)
0.6 2.3 GO:0045257 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.5 2.1 GO:0016939 kinesin II complex(GO:0016939)
0.5 3.2 GO:0005642 annulate lamellae(GO:0005642)
0.4 1.3 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.4 2.7 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.4 3.1 GO:0008278 cohesin complex(GO:0008278)
0.4 1.5 GO:0070545 PeBoW complex(GO:0070545)
0.4 1.1 GO:0032133 chromosome passenger complex(GO:0032133)
0.3 2.8 GO:0032389 MutLalpha complex(GO:0032389)
0.3 2.4 GO:0005663 DNA replication factor C complex(GO:0005663)
0.3 1.2 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.3 4.1 GO:0071778 obsolete WINAC complex(GO:0071778)
0.3 2.6 GO:0000796 condensin complex(GO:0000796)
0.3 1.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.3 0.9 GO:0070761 pre-snoRNP complex(GO:0070761)
0.3 0.9 GO:0001652 granular component(GO:0001652)
0.3 1.4 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.3 2.5 GO:0030681 nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.3 2.2 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.3 1.4 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.3 1.1 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.3 6.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.3 2.6 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.3 13.2 GO:0000786 nucleosome(GO:0000786)
0.3 2.0 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.3 0.8 GO:0043159 acrosomal matrix(GO:0043159)
0.2 3.2 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.2 0.7 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.2 3.8 GO:0031080 nuclear pore outer ring(GO:0031080)
0.2 3.2 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.2 1.9 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.2 1.9 GO:0031616 spindle pole centrosome(GO:0031616)
0.2 1.1 GO:0042599 lamellar body(GO:0042599)
0.2 1.9 GO:0005638 lamin filament(GO:0005638)
0.2 1.5 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.2 1.7 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.2 2.3 GO:0032039 integrator complex(GO:0032039)
0.2 0.8 GO:1902555 endoribonuclease complex(GO:1902555)
0.2 1.6 GO:0042382 paraspeckles(GO:0042382)
0.2 1.0 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.2 3.1 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.2 0.8 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.2 1.8 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.2 1.1 GO:0042575 DNA polymerase complex(GO:0042575)
0.2 1.8 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.2 1.9 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.2 14.9 GO:0016363 nuclear matrix(GO:0016363)
0.2 1.7 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.2 0.5 GO:0036452 ESCRT III complex(GO:0000815) ESCRT complex(GO:0036452)
0.2 0.6 GO:0005687 U4 snRNP(GO:0005687)
0.2 0.6 GO:0001940 female pronucleus(GO:0001939) male pronucleus(GO:0001940)
0.1 0.4 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540) U4/U6 snRNP(GO:0071001) spliceosomal tri-snRNP complex(GO:0097526)
0.1 1.2 GO:0005719 euchromatin(GO:0000791) nuclear euchromatin(GO:0005719)
0.1 0.6 GO:0042405 nuclear inclusion body(GO:0042405)
0.1 0.4 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.1 2.0 GO:0070822 Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822)
0.1 1.5 GO:0019908 nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.1 1.5 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1 6.3 GO:0042645 mitochondrial nucleoid(GO:0042645)
0.1 1.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 1.7 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 4.0 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 2.3 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.1 0.4 GO:0031213 RSF complex(GO:0031213)
0.1 1.1 GO:0032040 small-subunit processome(GO:0032040)
0.1 1.1 GO:0070652 HAUS complex(GO:0070652)
0.1 2.7 GO:0009986 cell surface(GO:0009986)
0.1 1.6 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 5.5 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 9.4 GO:0005643 nuclear pore(GO:0005643)
0.1 0.8 GO:0005827 polar microtubule(GO:0005827)
0.1 1.4 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 0.6 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 1.6 GO:0005833 hemoglobin complex(GO:0005833)
0.1 2.5 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.1 0.8 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 4.3 GO:0005814 centriole(GO:0005814)
0.1 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 0.3 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.1 0.5 GO:0000792 heterochromatin(GO:0000792)
0.1 0.7 GO:0030061 mitochondrial crista(GO:0030061)
0.1 0.3 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 1.2 GO:0070531 BRCA1-A complex(GO:0070531)
0.1 1.2 GO:0016585 obsolete chromatin remodeling complex(GO:0016585)
0.1 1.3 GO:0000178 exosome (RNase complex)(GO:0000178)
0.1 0.3 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 0.3 GO:0044295 axonal growth cone(GO:0044295)
0.1 4.5 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 1.1 GO:0046930 pore complex(GO:0046930)
0.1 0.5 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 2.4 GO:0005761 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.1 0.2 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.1 0.3 GO:0000124 SAGA complex(GO:0000124)
0.1 0.4 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 1.3 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 0.4 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.1 0.3 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 0.3 GO:0071817 MMXD complex(GO:0071817)
0.1 0.5 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.1 1.4 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.1 0.9 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 0.2 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.1 4.0 GO:0000785 chromatin(GO:0000785)
0.1 0.8 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 0.5 GO:0044452 nucleolar part(GO:0044452)
0.1 0.5 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.1 2.5 GO:0015030 Cajal body(GO:0015030)
0.1 0.3 GO:0032444 activin responsive factor complex(GO:0032444)
0.1 1.1 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 0.3 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 3.5 GO:0016605 PML body(GO:0016605)
0.1 0.8 GO:0005720 nuclear heterochromatin(GO:0005720)
0.1 0.3 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 0.3 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.1 0.5 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.1 3.5 GO:0000790 nuclear chromatin(GO:0000790)
0.1 0.1 GO:0048786 presynaptic active zone(GO:0048786)
0.1 0.3 GO:0072487 MSL complex(GO:0072487)
0.1 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 1.2 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.3 GO:0042587 glycogen granule(GO:0042587)
0.0 0.3 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.1 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0 1.1 GO:0005811 lipid particle(GO:0005811)
0.0 0.1 GO:0045120 pronucleus(GO:0045120)
0.0 0.1 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.9 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.7 GO:0090568 NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)
0.0 0.6 GO:0016235 aggresome(GO:0016235)
0.0 0.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.1 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.6 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.4 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.2 GO:0045298 tubulin complex(GO:0045298)
0.0 0.3 GO:0042555 MCM complex(GO:0042555)
0.0 0.4 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 1.5 GO:0000922 spindle pole(GO:0000922)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.1 GO:0005869 dynactin complex(GO:0005869)
0.0 0.3 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 6.8 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.5 GO:0001527 microfibril(GO:0001527)
0.0 3.5 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 28.9 GO:0005654 nucleoplasm(GO:0005654)
0.0 2.6 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898) cytoplasmic side of membrane(GO:0098562)
0.0 0.3 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 4.1 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.4 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 0.1 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.5 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.6 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.6 GO:0008287 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0 0.6 GO:0030666 endocytic vesicle membrane(GO:0030666)
0.0 0.7 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 0.8 GO:0030175 filopodium(GO:0030175)
0.0 1.7 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.6 GO:0031966 mitochondrial membrane(GO:0031966)
0.0 0.2 GO:0030315 T-tubule(GO:0030315)
0.0 0.8 GO:0005626 obsolete insoluble fraction(GO:0005626)
0.0 0.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.9 GO:0000502 proteasome complex(GO:0000502)
0.0 0.3 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.0 0.1 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.5 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.3 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.1 GO:0005858 axonemal dynein complex(GO:0005858) axoneme part(GO:0044447)
0.0 0.3 GO:0031526 brush border membrane(GO:0031526)
0.0 0.1 GO:0008385 IkappaB kinase complex(GO:0008385)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.9 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.9 2.6 GO:0003896 DNA primase activity(GO:0003896)
0.8 6.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.8 2.3 GO:0070361 mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
0.7 8.9 GO:0017070 U6 snRNA binding(GO:0017070)
0.6 1.8 GO:0000404 heteroduplex DNA loop binding(GO:0000404) double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181)
0.6 1.8 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.6 2.3 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.6 1.7 GO:0070260 5'-tyrosyl-DNA phosphodiesterase activity(GO:0070260)
0.6 0.6 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.5 1.5 GO:0008263 pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
0.5 1.5 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.5 1.4 GO:0015141 thiosulfate transmembrane transporter activity(GO:0015117) succinate transmembrane transporter activity(GO:0015141)
0.4 1.3 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.4 0.9 GO:0000700 mismatch base pair DNA N-glycosylase activity(GO:0000700)
0.4 2.2 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.4 1.7 GO:0000405 bubble DNA binding(GO:0000405)
0.4 2.1 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.4 1.7 GO:0003951 NAD+ kinase activity(GO:0003951)
0.4 1.2 GO:0070182 DNA polymerase binding(GO:0070182)
0.4 1.6 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.4 1.2 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.4 1.9 GO:0000827 inositol-1,3,4,5,6-pentakisphosphate kinase activity(GO:0000827) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.4 1.9 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.4 1.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.4 1.1 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.3 3.8 GO:0035173 histone kinase activity(GO:0035173)
0.3 1.0 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
0.3 0.9 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.3 1.6 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.3 1.2 GO:0004713 protein tyrosine kinase activity(GO:0004713)
0.3 4.1 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.3 1.9 GO:0030911 TPR domain binding(GO:0030911)
0.3 1.1 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.3 1.4 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.3 0.8 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.3 0.5 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.3 1.4 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.3 2.4 GO:0015288 porin activity(GO:0015288)
0.3 1.0 GO:0098847 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.3 0.8 GO:0043426 histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648) MRF binding(GO:0043426)
0.3 0.8 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.3 4.6 GO:0004532 exoribonuclease activity(GO:0004532)
0.2 1.0 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.2 2.4 GO:0003701 obsolete RNA polymerase I transcription factor activity(GO:0003701)
0.2 0.9 GO:0016531 copper chaperone activity(GO:0016531)
0.2 11.2 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.2 0.5 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.2 0.9 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.2 0.4 GO:0070410 co-SMAD binding(GO:0070410)
0.2 1.3 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.2 1.9 GO:0003993 acid phosphatase activity(GO:0003993)
0.2 2.7 GO:0004526 ribonuclease P activity(GO:0004526) tRNA-specific ribonuclease activity(GO:0004549)
0.2 0.6 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.2 0.8 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.2 1.6 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.2 1.1 GO:0051766 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.2 0.9 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.2 0.9 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.2 0.5 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.2 0.9 GO:0004306 ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
0.2 0.5 GO:0036002 pre-mRNA binding(GO:0036002)
0.2 0.5 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.2 0.5 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.2 5.4 GO:0003724 RNA helicase activity(GO:0003724)
0.2 1.1 GO:0031491 nucleosome binding(GO:0031491)
0.2 4.7 GO:0034061 DNA-directed DNA polymerase activity(GO:0003887) DNA polymerase activity(GO:0034061)
0.2 1.3 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.2 0.5 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.2 1.4 GO:0019826 oxygen sensor activity(GO:0019826)
0.2 1.5 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 0.3 GO:0048039 ubiquinone binding(GO:0048039)
0.1 0.4 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.1 2.0 GO:0031593 polyubiquitin binding(GO:0031593)
0.1 1.5 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 1.2 GO:0070087 chromo shadow domain binding(GO:0070087)
0.1 0.6 GO:0002060 purine nucleobase binding(GO:0002060)
0.1 2.3 GO:0043022 ribosome binding(GO:0043022)
0.1 0.5 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.1 0.5 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 0.9 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 0.1 GO:0030611 arsenate reductase activity(GO:0030611)
0.1 2.6 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.1 0.9 GO:0008732 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.1 0.9 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 0.6 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.1 0.3 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.1 0.4 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.1 0.4 GO:0005174 CD40 receptor binding(GO:0005174)
0.1 1.6 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 1.7 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 0.8 GO:0050700 CARD domain binding(GO:0050700)
0.1 0.7 GO:0070568 guanylyltransferase activity(GO:0070568)
0.1 0.5 GO:0008148 obsolete negative transcription elongation factor activity(GO:0008148)
0.1 0.7 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 0.5 GO:0004738 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.1 0.7 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.1 5.8 GO:0042826 histone deacetylase binding(GO:0042826)
0.1 0.7 GO:0050693 LBD domain binding(GO:0050693)
0.1 4.2 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.1 1.1 GO:0002039 p53 binding(GO:0002039)
0.1 0.8 GO:0019789 SUMO transferase activity(GO:0019789)
0.1 2.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 1.1 GO:0050897 cobalt ion binding(GO:0050897)
0.1 2.2 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 0.8 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.1 0.9 GO:1901567 icosanoid binding(GO:0050542) arachidonic acid binding(GO:0050544) fatty acid derivative binding(GO:1901567)
0.1 0.3 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 0.3 GO:0043515 kinetochore binding(GO:0043515)
0.1 4.7 GO:0050136 NADH dehydrogenase activity(GO:0003954) NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.8 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 1.5 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.1 0.6 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 0.9 GO:0004312 fatty acid synthase activity(GO:0004312)
0.1 0.7 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 0.6 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 0.3 GO:0004672 protein kinase activity(GO:0004672)
0.1 0.5 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.1 8.8 GO:0016566 obsolete specific transcriptional repressor activity(GO:0016566)
0.1 0.8 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 0.3 GO:0008159 obsolete positive transcription elongation factor activity(GO:0008159)
0.1 0.8 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.1 0.7 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 1.9 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 1.1 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.1 0.4 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.1 0.3 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.1 2.2 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.1 0.8 GO:0061659 ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.1 0.8 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 0.8 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
0.1 1.4 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.1 1.8 GO:0035064 methylated histone binding(GO:0035064)
0.1 1.0 GO:0003711 obsolete transcription elongation regulator activity(GO:0003711)
0.1 0.4 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.1 0.3 GO:0015187 glycine transmembrane transporter activity(GO:0015187) glycine:sodium symporter activity(GO:0015375)
0.1 0.6 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.1 0.4 GO:0008252 nucleotidase activity(GO:0008252)
0.1 0.9 GO:0060590 ATPase regulator activity(GO:0060590)
0.1 0.4 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 1.2 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 2.0 GO:0004519 endonuclease activity(GO:0004519)
0.1 0.4 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.1 0.7 GO:0016421 CoA carboxylase activity(GO:0016421)
0.1 3.4 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.1 0.1 GO:0019104 DNA N-glycosylase activity(GO:0019104)
0.1 0.5 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 0.3 GO:0042895 antibiotic transporter activity(GO:0042895)
0.1 0.3 GO:0015925 galactosidase activity(GO:0015925)
0.1 0.3 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.1 0.4 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.2 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 0.3 GO:0019103 pyrimidine nucleotide binding(GO:0019103) deoxyribonucleotide binding(GO:0032552)
0.1 2.3 GO:0036459 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.1 0.2 GO:0004083 bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619) bisphosphoglycerate phosphatase activity(GO:0034416)
0.1 0.3 GO:0004428 obsolete inositol or phosphatidylinositol kinase activity(GO:0004428)
0.1 0.4 GO:0004457 lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
0.1 1.3 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 0.6 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.1 0.3 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 0.2 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.1 3.2 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.1 0.6 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.1 4.6 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.1 0.2 GO:0009374 biotin binding(GO:0009374)
0.0 0.9 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.4 GO:0042054 histone methyltransferase activity(GO:0042054)
0.0 1.2 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.5 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.9 GO:0016986 obsolete transcription initiation factor activity(GO:0016986)
0.0 1.8 GO:0050681 androgen receptor binding(GO:0050681)
0.0 5.4 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 3.0 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.3 GO:0030332 cyclin binding(GO:0030332)
0.0 0.1 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.6 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.6 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.3 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.2 GO:0055103 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.5 GO:0017091 AU-rich element binding(GO:0017091)
0.0 1.0 GO:0000049 tRNA binding(GO:0000049)
0.0 0.8 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.2 GO:0000247 C-8 sterol isomerase activity(GO:0000247)
0.0 0.2 GO:0045502 dynein binding(GO:0045502)
0.0 1.4 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.6 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.9 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0 0.6 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.5 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 4.1 GO:0008168 methyltransferase activity(GO:0008168)
0.0 0.6 GO:0005521 lamin binding(GO:0005521)
0.0 1.7 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.2 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.1 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.0 0.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 2.7 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.2 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.8 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 3.6 GO:0004386 helicase activity(GO:0004386)
0.0 0.1 GO:0005112 Notch binding(GO:0005112)
0.0 1.0 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.4 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.0 1.1 GO:0004536 deoxyribonuclease activity(GO:0004536)
0.0 2.7 GO:0001071 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 0.4 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.0 0.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.6 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 1.3 GO:0032934 sterol binding(GO:0032934)
0.0 0.3 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0 0.3 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.0 0.2 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 3.7 GO:0003682 chromatin binding(GO:0003682)
0.0 0.3 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.3 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.2 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.2 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 2.5 GO:0010843 obsolete promoter binding(GO:0010843)
0.0 0.2 GO:0016741 transferase activity, transferring one-carbon groups(GO:0016741)
0.0 3.5 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.1 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.4 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.1 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 4.8 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.5 GO:0042393 histone binding(GO:0042393)
0.0 0.2 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 1.5 GO:0050660 flavin adenine dinucleotide binding(GO:0050660)
0.0 0.3 GO:0019894 kinesin binding(GO:0019894)
0.0 0.8 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 4.4 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.0 0.4 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 1.0 GO:0019903 protein phosphatase binding(GO:0019903)
0.0 0.3 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.3 GO:0005123 death receptor binding(GO:0005123)
0.0 0.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.3 GO:0045296 cadherin binding(GO:0045296)
0.0 1.7 GO:0019207 kinase regulator activity(GO:0019207)
0.0 0.1 GO:0031701 angiotensin receptor binding(GO:0031701)
0.0 0.3 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.4 GO:0008430 selenium binding(GO:0008430)
0.0 1.0 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 0.4 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0 0.1 GO:0019843 rRNA binding(GO:0019843)
0.0 0.1 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.0 0.2 GO:0005048 signal sequence binding(GO:0005048)
0.0 0.3 GO:0004221 obsolete ubiquitin thiolesterase activity(GO:0004221)
0.0 0.2 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.2 GO:0030276 clathrin binding(GO:0030276)
0.0 0.0 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.0 0.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.2 GO:0005537 mannose binding(GO:0005537)
0.0 0.8 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.6 GO:0005507 copper ion binding(GO:0005507)
0.0 0.4 GO:0051087 chaperone binding(GO:0051087)
0.0 1.7 GO:0005267 potassium channel activity(GO:0005267)
0.0 3.2 GO:0003924 GTPase activity(GO:0003924)
0.0 0.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 1.1 GO:0003702 obsolete RNA polymerase II transcription factor activity(GO:0003702)
0.0 0.2 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 17.9 GO:0003677 DNA binding(GO:0003677)
0.0 0.4 GO:0017137 Rab GTPase binding(GO:0017137)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.7 ST_INTERFERON_GAMMA_PATHWAY Interferon gamma pathway.
0.1 2.2 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 1.1 ST_PAC1_RECEPTOR_PATHWAY PAC1 Receptor Pathway
0.1 1.6 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 3.3 ST_P38_MAPK_PATHWAY p38 MAPK Pathway
0.1 0.5 SA_G1_AND_S_PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1 0.3 ST_JAK_STAT_PATHWAY Jak-STAT Pathway
0.1 0.7 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.2 SIG_IL4RECEPTOR_IN_B_LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.7 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.0 2.1 ST_T_CELL_SIGNAL_TRANSDUCTION T Cell Signal Transduction
0.0 0.3 ST_TUMOR_NECROSIS_FACTOR_PATHWAY Tumor Necrosis Factor Pathway.