Motif ID: OTP_PHOX2B_LHX1_LMX1A_LHX5_HOXC4

Z-value: 1.139







Network of associatons between targets according to the STRING database.



First level regulatory network of OTP_PHOX2B_LHX1_LMX1A_LHX5_HOXC4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_+_1674982 5.821 ENST00000572048.1
ENST00000573763.1
SERPINF1

serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1

chr16_-_28634874 2.911 ENST00000395609.1
ENST00000350842.4
SULT1A1

sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1

chr19_+_50016610 2.826 ENST00000596975.1
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr19_+_50016411 2.821 ENST00000426395.3
ENST00000600273.1
ENST00000599988.1
FCGRT


Fc fragment of IgG, receptor, transporter, alpha


chr5_+_95066823 2.277 ENST00000506817.1
ENST00000379982.3
RHOBTB3

Rho-related BTB domain containing 3

chr3_+_157154578 2.059 ENST00000295927.3
PTX3
pentraxin 3, long
chr7_+_134528635 1.712 ENST00000445569.2
CALD1
caldesmon 1
chr11_-_63376013 1.557 ENST00000540943.1
PLA2G16
phospholipase A2, group XVI
chr12_+_26348246 1.555 ENST00000422622.2
SSPN
sarcospan
chr10_+_94451574 1.517 ENST00000492654.2
HHEX
hematopoietically expressed homeobox
chr7_+_138145076 1.284 ENST00000343526.4
TRIM24
tripartite motif containing 24
chr17_-_64225508 1.279 ENST00000205948.6
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr16_-_30122717 1.210 ENST00000566613.1
GDPD3
glycerophosphodiester phosphodiesterase domain containing 3
chr20_-_33735070 1.154 ENST00000374491.3
ENST00000542871.1
ENST00000374492.3
EDEM2


ER degradation enhancer, mannosidase alpha-like 2


chr7_-_87342564 1.096 ENST00000265724.3
ENST00000416177.1
ABCB1

ATP-binding cassette, sub-family B (MDR/TAP), member 1

chr12_+_26348429 1.089 ENST00000242729.2
SSPN
sarcospan
chr1_-_92371839 1.000 ENST00000370399.2
TGFBR3
transforming growth factor, beta receptor III
chr15_+_58702742 0.996 ENST00000356113.6
ENST00000414170.3
LIPC

lipase, hepatic

chr11_+_114168085 0.989 ENST00000541754.1
NNMT
nicotinamide N-methyltransferase
chr3_-_149293990 0.922 ENST00000472417.1
WWTR1
WW domain containing transcription regulator 1
chr7_+_102553430 0.905 ENST00000339431.4
ENST00000249377.4
LRRC17

leucine rich repeat containing 17

chr12_+_26348582 0.853 ENST00000535504.1
SSPN
sarcospan
chr1_+_117544366 0.724 ENST00000256652.4
ENST00000369470.1
CD101

CD101 molecule

chr10_-_75415825 0.719 ENST00000394810.2
SYNPO2L
synaptopodin 2-like
chr1_-_57045228 0.688 ENST00000371250.3
PPAP2B
phosphatidic acid phosphatase type 2B
chr7_-_143599207 0.686 ENST00000355951.2
ENST00000479870.1
ENST00000478172.1
FAM115A


family with sequence similarity 115, member A


chr4_+_155484155 0.658 ENST00000509493.1
FGB
fibrinogen beta chain
chr2_+_152214098 0.596 ENST00000243347.3
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr7_-_107642348 0.593 ENST00000393561.1
LAMB1
laminin, beta 1
chr19_-_51920952 0.583 ENST00000356298.5
ENST00000339313.5
ENST00000529627.1
ENST00000439889.2
ENST00000353836.5
ENST00000432469.2
SIGLEC10





sialic acid binding Ig-like lectin 10





chr3_-_114477962 0.523 ENST00000471418.1
ZBTB20
zinc finger and BTB domain containing 20
chr2_-_190927447 0.516 ENST00000260950.4
MSTN
myostatin
chr3_-_114477787 0.499 ENST00000464560.1
ZBTB20
zinc finger and BTB domain containing 20
chr12_+_64798095 0.498 ENST00000332707.5
XPOT
exportin, tRNA
chr3_-_185538849 0.496 ENST00000421047.2
IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr11_-_327537 0.481 ENST00000602735.1
IFITM3
interferon induced transmembrane protein 3
chr4_-_185275104 0.473 ENST00000317596.3
RP11-290F5.2
RP11-290F5.2
chr3_-_99569821 0.458 ENST00000487087.1
FILIP1L
filamin A interacting protein 1-like
chr4_+_155484103 0.440 ENST00000302068.4
FGB
fibrinogen beta chain
chr19_-_14064114 0.436 ENST00000585607.1
ENST00000538517.2
ENST00000587458.1
ENST00000538371.2
PODNL1



podocan-like 1



chr9_+_125132803 0.431 ENST00000540753.1
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr1_-_109935819 0.381 ENST00000538502.1
SORT1
sortilin 1
chr3_+_12329397 0.379 ENST00000397015.2
PPARG
peroxisome proliferator-activated receptor gamma
chr7_+_150020329 0.376 ENST00000323078.7
LRRC61
leucine rich repeat containing 61
chr14_+_50234309 0.364 ENST00000298307.5
KLHDC2
kelch domain containing 2
chr3_-_149095652 0.362 ENST00000305366.3
TM4SF1
transmembrane 4 L six family member 1
chr1_-_153518270 0.335 ENST00000354332.4
ENST00000368716.4
S100A4

S100 calcium binding protein A4

chr7_+_150020363 0.324 ENST00000359623.4
ENST00000493307.1
LRRC61

leucine rich repeat containing 61

chr6_-_32157947 0.310 ENST00000375050.4
PBX2
pre-B-cell leukemia homeobox 2
chr17_-_46688334 0.309 ENST00000239165.7
HOXB7
homeobox B7
chr7_+_73868120 0.307 ENST00000265755.3
GTF2IRD1
GTF2I repeat domain containing 1
chr7_+_73868439 0.296 ENST00000424337.2
GTF2IRD1
GTF2I repeat domain containing 1
chr13_-_38172863 0.277 ENST00000541481.1
ENST00000379743.4
ENST00000379742.4
ENST00000379749.4
ENST00000541179.1
ENST00000379747.4
POSTN





periostin, osteoblast specific factor





chr5_-_176889381 0.276 ENST00000393563.4
ENST00000512501.1
DBN1

drebrin 1

chr2_+_90211643 0.273 ENST00000390277.2
IGKV3D-11
immunoglobulin kappa variable 3D-11
chr8_-_90769422 0.265 ENST00000524190.1
ENST00000523859.1
RP11-37B2.1

RP11-37B2.1

chr2_+_187454749 0.249 ENST00000261023.3
ENST00000374907.3
ITGAV

integrin, alpha V

chr3_+_12329358 0.244 ENST00000309576.6
PPARG
peroxisome proliferator-activated receptor gamma
chr2_+_109237717 0.237 ENST00000409441.1
LIMS1
LIM and senescent cell antigen-like domains 1
chr6_+_26440700 0.232 ENST00000494393.1
ENST00000482451.1
ENST00000244519.2
ENST00000339789.4
ENST00000471353.1
ENST00000361232.3
ENST00000487627.1
ENST00000496719.1
ENST00000490254.1
ENST00000487272.1
BTN3A3









butyrophilin, subfamily 3, member A3









chr1_-_101360331 0.219 ENST00000416479.1
ENST00000370113.3
EXTL2

exostosin-like glycosyltransferase 2

chr6_-_133035185 0.215 ENST00000367928.4
VNN1
vanin 1
chr10_+_101542462 0.213 ENST00000370449.4
ENST00000370434.1
ABCC2

ATP-binding cassette, sub-family C (CFTR/MRP), member 2

chr1_-_190446759 0.206 ENST00000367462.3
BRINP3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr13_+_53602894 0.204 ENST00000219022.2
OLFM4
olfactomedin 4
chr9_+_90112590 0.204 ENST00000472284.1
DAPK1
death-associated protein kinase 1
chr9_+_90112767 0.200 ENST00000408954.3
DAPK1
death-associated protein kinase 1
chr9_-_99540328 0.195 ENST00000223428.4
ENST00000375231.1
ENST00000374641.3
ZNF510


zinc finger protein 510


chr2_+_102456277 0.193 ENST00000421882.1
MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr6_+_42749759 0.192 ENST00000314073.5
GLTSCR1L
GLTSCR1-like
chr16_-_66583701 0.189 ENST00000527800.1
ENST00000525974.1
ENST00000563369.2
TK2


thymidine kinase 2, mitochondrial


chr20_+_30697298 0.181 ENST00000398022.2
TM9SF4
transmembrane 9 superfamily protein member 4
chr6_-_52705641 0.180 ENST00000370989.2
GSTA5
glutathione S-transferase alpha 5
chr19_+_21324827 0.176 ENST00000600692.1
ENST00000599296.1
ENST00000594425.1
ENST00000311048.7
ZNF431



zinc finger protein 431



chr20_+_56136136 0.171 ENST00000319441.4
ENST00000543666.1
PCK1

phosphoenolpyruvate carboxykinase 1 (soluble)

chr11_-_128894053 0.169 ENST00000392657.3
ARHGAP32
Rho GTPase activating protein 32
chr19_-_14945933 0.163 ENST00000322301.3
OR7A5
olfactory receptor, family 7, subfamily A, member 5
chr20_+_57594309 0.163 ENST00000217133.1
TUBB1
tubulin, beta 1 class VI
chr7_+_73868220 0.162 ENST00000455841.2
GTF2IRD1
GTF2I repeat domain containing 1
chr15_-_55489097 0.155 ENST00000260443.4
RSL24D1
ribosomal L24 domain containing 1
chr19_-_36304201 0.139 ENST00000301175.3
PRODH2
proline dehydrogenase (oxidase) 2
chr2_+_234826016 0.135 ENST00000324695.4
ENST00000433712.2
TRPM8

transient receptor potential cation channel, subfamily M, member 8

chrX_+_22050546 0.135 ENST00000379374.4
PHEX
phosphate regulating endopeptidase homolog, X-linked
chr1_-_212965104 0.134 ENST00000422588.2
ENST00000366975.6
ENST00000366977.3
ENST00000366976.1
NSL1



NSL1, MIS12 kinetochore complex component



chrX_-_106243451 0.130 ENST00000355610.4
ENST00000535534.1
MORC4

MORC family CW-type zinc finger 4

chrX_+_77166172 0.129 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
ATP7A


ATPase, Cu++ transporting, alpha polypeptide


chr16_-_71842941 0.129 ENST00000423132.2
ENST00000433195.2
ENST00000569748.1
ENST00000570017.1
AP1G1



adaptor-related protein complex 1, gamma 1 subunit



chr6_+_26365443 0.128 ENST00000527422.1
ENST00000356386.2
ENST00000396934.3
ENST00000377708.2
ENST00000396948.1
ENST00000508906.2
BTN3A2





butyrophilin, subfamily 3, member A2





chr12_-_22063787 0.128 ENST00000544039.1
ABCC9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr1_-_153919128 0.126 ENST00000361217.4
DENND4B
DENN/MADD domain containing 4B
chr17_-_72772462 0.125 ENST00000582870.1
ENST00000581136.1
ENST00000357814.3
ENST00000579218.1
ENST00000583476.1
ENST00000580301.1
ENST00000583757.1
ENST00000582524.1
NAT9







N-acetyltransferase 9 (GCN5-related, putative)







chr17_-_53800217 0.123 ENST00000424486.2
TMEM100
transmembrane protein 100
chr2_-_216946500 0.122 ENST00000265322.7
PECR
peroxisomal trans-2-enoyl-CoA reductase
chr15_+_84115868 0.121 ENST00000427482.2
SH3GL3
SH3-domain GRB2-like 3
chr2_-_27886460 0.120 ENST00000404798.2
ENST00000405491.1
ENST00000464789.2
ENST00000406540.1
SUPT7L



suppressor of Ty 7 (S. cerevisiae)-like



chr12_-_23737534 0.115 ENST00000396007.2
SOX5
SRY (sex determining region Y)-box 5
chr11_+_59824127 0.112 ENST00000278865.3
MS4A3
membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr2_-_8977714 0.111 ENST00000319688.5
ENST00000489024.1
ENST00000256707.3
ENST00000427284.1
ENST00000418530.1
ENST00000473731.1
KIDINS220





kinase D-interacting substrate, 220kDa





chr12_+_104337515 0.111 ENST00000550595.1
HSP90B1
heat shock protein 90kDa beta (Grp94), member 1
chr18_-_53177984 0.109 ENST00000543082.1
TCF4
transcription factor 4
chr17_+_48823896 0.108 ENST00000511974.1
LUC7L3
LUC7-like 3 (S. cerevisiae)
chr6_+_158733692 0.106 ENST00000367094.2
ENST00000367097.3
TULP4

tubby like protein 4

chr2_-_27886676 0.104 ENST00000337768.5
SUPT7L
suppressor of Ty 7 (S. cerevisiae)-like
chr2_-_21022818 0.104 ENST00000440866.2
ENST00000541941.1
ENST00000402479.2
ENST00000435420.2
ENST00000432947.1
ENST00000403006.2
ENST00000419825.2
ENST00000381090.3
ENST00000237822.3
ENST00000412261.1
C2orf43









chromosome 2 open reading frame 43









chr6_-_91296602 0.103 ENST00000369325.3
ENST00000369327.3
MAP3K7

mitogen-activated protein kinase kinase kinase 7

chr9_+_34652164 0.102 ENST00000441545.2
ENST00000553620.1
IL11RA

interleukin 11 receptor, alpha

chr3_+_44840679 0.095 ENST00000425755.1
KIF15
kinesin family member 15
chr19_+_49199209 0.095 ENST00000522966.1
ENST00000425340.2
ENST00000391876.4
FUT2


fucosyltransferase 2 (secretor status included)


chr6_-_91296737 0.094 ENST00000369332.3
ENST00000369329.3
MAP3K7

mitogen-activated protein kinase kinase kinase 7

chr7_-_101272576 0.093 ENST00000223167.4
MYL10
myosin, light chain 10, regulatory
chr16_-_71843047 0.090 ENST00000299980.4
ENST00000393512.3
AP1G1

adaptor-related protein complex 1, gamma 1 subunit

chr11_+_7618413 0.090 ENST00000528883.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr16_+_28565230 0.088 ENST00000317058.3
CCDC101
coiled-coil domain containing 101
chr13_-_36050819 0.081 ENST00000379919.4
MAB21L1
mab-21-like 1 (C. elegans)
chr2_+_202047596 0.080 ENST00000286186.6
ENST00000360132.3
CASP10

caspase 10, apoptosis-related cysteine peptidase

chr6_+_26402465 0.079 ENST00000476549.2
ENST00000289361.6
ENST00000450085.2
ENST00000425234.2
ENST00000427334.1
ENST00000506698.1
BTN3A1





butyrophilin, subfamily 3, member A1





chr6_+_26087509 0.079 ENST00000397022.3
ENST00000353147.5
ENST00000352392.4
ENST00000349999.4
ENST00000317896.7
ENST00000357618.5
ENST00000470149.1
ENST00000336625.8
ENST00000461397.1
ENST00000488199.1
HFE









hemochromatosis









chr3_+_149191723 0.079 ENST00000305354.4
TM4SF4
transmembrane 4 L six family member 4
chr18_-_51750948 0.078 ENST00000583046.1
ENST00000398398.2
MBD2

methyl-CpG binding domain protein 2

chr7_-_140482926 0.077 ENST00000496384.2
BRAF
v-raf murine sarcoma viral oncogene homolog B
chr8_-_86253888 0.076 ENST00000522389.1
ENST00000432364.2
ENST00000517618.1
CA1


carbonic anhydrase I


chr11_+_59824060 0.075 ENST00000395032.2
ENST00000358152.2
MS4A3

membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)

chr2_-_191115229 0.072 ENST00000409820.2
ENST00000410045.1
HIBCH

3-hydroxyisobutyryl-CoA hydrolase

chr2_-_89385283 0.071 ENST00000390252.2
IGKV3-15
immunoglobulin kappa variable 3-15
chr4_+_5527117 0.071 ENST00000505296.1
C4orf6
chromosome 4 open reading frame 6
chr17_-_39093672 0.070 ENST00000209718.3
ENST00000436344.3
ENST00000485751.1
KRT23


keratin 23 (histone deacetylase inducible)


chr2_+_27886330 0.067 ENST00000326019.6
SLC4A1AP
solute carrier family 4 (anion exchanger), member 1, adaptor protein
chr3_+_69812701 0.066 ENST00000472437.1
MITF
microphthalmia-associated transcription factor
chr12_-_25150373 0.065 ENST00000549828.1
C12orf77
chromosome 12 open reading frame 77
chr10_+_18549645 0.065 ENST00000396576.2
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr12_-_10022735 0.064 ENST00000228438.2
CLEC2B
C-type lectin domain family 2, member B
chr18_+_46065393 0.062 ENST00000256413.3
CTIF
CBP80/20-dependent translation initiation factor
chr5_+_175288631 0.062 ENST00000509837.1
CPLX2
complexin 2
chr6_-_29527702 0.060 ENST00000377050.4
UBD
ubiquitin D
chr12_-_112123524 0.059 ENST00000327551.6
BRAP
BRCA1 associated protein
chr6_+_26087646 0.055 ENST00000309234.6
HFE
hemochromatosis
chr17_+_66511540 0.054 ENST00000588188.2
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr4_+_37455536 0.054 ENST00000381980.4
ENST00000508175.1
C4orf19

chromosome 4 open reading frame 19

chrX_-_100872911 0.054 ENST00000361910.4
ENST00000539247.1
ENST00000538627.1
ARMCX6


armadillo repeat containing, X-linked 6


chr5_-_20575959 0.052 ENST00000507958.1
CDH18
cadherin 18, type 2
chr5_-_125930929 0.052 ENST00000553117.1
ENST00000447989.2
ENST00000409134.3
ALDH7A1


aldehyde dehydrogenase 7 family, member A1


chr19_-_3772209 0.052 ENST00000555978.1
ENST00000555633.1
RAX2

retina and anterior neural fold homeobox 2

chr2_-_37068530 0.051 ENST00000593798.1
AC007382.1
Uncharacterized protein
chr2_+_202047843 0.051 ENST00000272879.5
ENST00000374650.3
ENST00000346817.5
ENST00000313728.7
ENST00000448480.1
CASP10




caspase 10, apoptosis-related cysteine peptidase




chr19_-_19887185 0.050 ENST00000590092.1
ENST00000589910.1
ENST00000589508.1
ENST00000586645.1
ENST00000586816.1
ENST00000588223.1
ENST00000586885.1
LINC00663






long intergenic non-protein coding RNA 663






chr8_-_57123815 0.046 ENST00000316981.3
ENST00000423799.2
ENST00000429357.2
PLAG1


pleiomorphic adenoma gene 1


chr12_+_20963632 0.045 ENST00000540853.1
ENST00000261196.2
SLCO1B3

solute carrier organic anion transporter family, member 1B3

chrX_+_108779004 0.044 ENST00000218004.1
NXT2
nuclear transport factor 2-like export factor 2
chr17_+_48823975 0.042 ENST00000513969.1
ENST00000503728.1
LUC7L3

LUC7-like 3 (S. cerevisiae)

chr16_-_66584059 0.041 ENST00000417693.3
ENST00000544898.1
ENST00000569718.1
ENST00000527284.1
ENST00000299697.7
ENST00000451102.2
TK2





thymidine kinase 2, mitochondrial





chr7_-_64023441 0.040 ENST00000309683.6
ZNF680
zinc finger protein 680
chr3_+_141457105 0.040 ENST00000480908.1
ENST00000393000.3
RNF7

ring finger protein 7

chr8_+_121137333 0.040 ENST00000309791.4
ENST00000297848.3
ENST00000247781.3
COL14A1


collagen, type XIV, alpha 1


chr19_+_21264980 0.039 ENST00000596053.1
ENST00000597086.1
ENST00000596143.1
ENST00000596367.1
ENST00000601416.1
ZNF714




zinc finger protein 714




chr3_+_69812877 0.039 ENST00000457080.1
ENST00000328528.6
MITF

microphthalmia-associated transcription factor

chr9_-_21202204 0.038 ENST00000239347.3
IFNA7
interferon, alpha 7
chr1_-_233431458 0.038 ENST00000258229.9
ENST00000430153.1
PCNXL2

pecanex-like 2 (Drosophila)

chr1_+_10509971 0.037 ENST00000320498.4
CORT
cortistatin
chr3_+_141457030 0.037 ENST00000273480.3
RNF7
ring finger protein 7
chr4_+_71108300 0.036 ENST00000304954.3
CSN3
casein kappa
chr17_-_37607497 0.036 ENST00000394287.3
ENST00000300651.6
MED1

mediator complex subunit 1

chr2_+_68962014 0.035 ENST00000467265.1
ARHGAP25
Rho GTPase activating protein 25
chr14_+_102276209 0.034 ENST00000445439.3
ENST00000334743.5
ENST00000557095.1
PPP2R5C


protein phosphatase 2, regulatory subunit B', gamma


chrX_+_55744166 0.034 ENST00000374941.4
ENST00000414239.1
RRAGB

Ras-related GTP binding B

chr18_-_52989525 0.034 ENST00000457482.3
TCF4
transcription factor 4
chrX_+_55744228 0.033 ENST00000262850.7
RRAGB
Ras-related GTP binding B
chr14_+_72052983 0.032 ENST00000358550.2
SIPA1L1
signal-induced proliferation-associated 1 like 1
chr12_-_118796910 0.032 ENST00000541186.1
ENST00000539872.1
TAOK3

TAO kinase 3

chr3_+_139063372 0.030 ENST00000478464.1
MRPS22
mitochondrial ribosomal protein S22
chr5_-_70316737 0.029 ENST00000194097.4
NAIP
NLR family, apoptosis inhibitory protein
chr6_-_112115074 0.028 ENST00000368667.2
FYN
FYN oncogene related to SRC, FGR, YES
chr1_+_78769549 0.026 ENST00000370758.1
PTGFR
prostaglandin F receptor (FP)
chr18_-_47018769 0.026 ENST00000583637.1
ENST00000578528.1
ENST00000578532.1
ENST00000580387.1
ENST00000579248.1
ENST00000581373.1
RPL17





ribosomal protein L17





chr3_-_9994021 0.025 ENST00000411976.2
ENST00000412055.1
PRRT3

proline-rich transmembrane protein 3

chrX_+_134975753 0.025 ENST00000535938.1
SAGE1
sarcoma antigen 1
chr5_+_81575281 0.025 ENST00000380167.4
ATP6AP1L
ATPase, H+ transporting, lysosomal accessory protein 1-like
chr5_-_149829244 0.024 ENST00000312037.5
RPS14
ribosomal protein S14
chrX_+_134975858 0.023 ENST00000537770.1
SAGE1
sarcoma antigen 1
chr2_-_136678123 0.023 ENST00000422708.1
DARS
aspartyl-tRNA synthetase
chr18_-_52989217 0.021 ENST00000570287.2
TCF4
transcription factor 4
chr15_+_75970672 0.020 ENST00000435356.1
AC105020.1
Uncharacterized protein; cDNA FLJ12988 fis, clone NT2RP3000080
chr10_-_115904361 0.020 ENST00000428953.1
ENST00000543782.1
C10orf118

chromosome 10 open reading frame 118

chr1_+_81771806 0.019 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
LPHN2





latrophilin 2





chr2_-_25391468 0.019 ENST00000395826.2
POMC
proopiomelanocortin
chr2_+_102953608 0.019 ENST00000311734.2
ENST00000409584.1
IL1RL1

interleukin 1 receptor-like 1

chr21_-_27423339 0.018 ENST00000415997.1
APP
amyloid beta (A4) precursor protein
chr9_-_21351377 0.018 ENST00000380210.1
IFNA6
interferon, alpha 6
chr3_+_186353756 0.018 ENST00000431018.1
ENST00000450521.1
ENST00000539949.1
FETUB


fetuin B


chr2_-_25391425 0.018 ENST00000264708.3
ENST00000449220.1
POMC

proopiomelanocortin

chr1_+_57320437 0.017 ENST00000361249.3
C8A
complement component 8, alpha polypeptide
chr4_+_113568207 0.017 ENST00000511529.1
LARP7
La ribonucleoprotein domain family, member 7
chr8_-_30670384 0.017 ENST00000221138.4
ENST00000518243.1
PPP2CB

protein phosphatase 2, catalytic subunit, beta isozyme

chr10_-_101989315 0.017 ENST00000370397.7
CHUK
conserved helix-loop-helix ubiquitous kinase
chr11_+_59856130 0.016 ENST00000278888.3
MS4A2
membrane-spanning 4-domains, subfamily A, member 2
chr7_-_44580861 0.016 ENST00000546276.1
ENST00000289547.4
ENST00000381160.3
ENST00000423141.1
NPC1L1



NPC1-like 1



chr2_-_74618964 0.015 ENST00000417090.1
ENST00000409868.1
DCTN1

dynactin 1

chr11_+_62037622 0.015 ENST00000227918.2
ENST00000525380.1
SCGB2A2

secretoglobin, family 2A, member 2

chr1_+_146714291 0.015 ENST00000431239.1
ENST00000369259.3
ENST00000369258.4
ENST00000361293.5
CHD1L



chromodomain helicase DNA binding protein 1-like



chr11_-_13011081 0.015 ENST00000532541.1
ENST00000526388.1
ENST00000534477.1
ENST00000531402.1
ENST00000527945.1
ENST00000504230.2
LINC00958





long intergenic non-protein coding RNA 958





chr4_-_100356551 0.014 ENST00000209665.4
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 5.8 GO:0007614 short-term memory(GO:0007614)
0.4 1.3 GO:1901419 regulation of response to alcohol(GO:1901419)
0.4 1.5 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.3 2.1 GO:0008228 opsonization(GO:0008228)
0.3 1.0 GO:0060318 definitive erythrocyte differentiation(GO:0060318)
0.2 0.5 GO:0014889 muscle atrophy(GO:0014889) regulation of skeletal muscle tissue growth(GO:0048631)
0.2 1.3 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.2 0.9 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.1 2.9 GO:0009812 flavonoid metabolic process(GO:0009812)
0.1 0.6 GO:0055098 response to low-density lipoprotein particle(GO:0055098) regulation of cholesterol transporter activity(GO:0060694)
0.1 1.0 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 2.3 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.1 1.4 GO:0006071 glycerol metabolic process(GO:0006071)
0.1 0.7 GO:0008354 germ cell migration(GO:0008354)
0.1 0.4 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509) plasma membrane to endosome transport(GO:0048227) negative regulation of lipoprotein lipase activity(GO:0051005) negative regulation of lipase activity(GO:0060192)
0.1 5.6 GO:0019882 antigen processing and presentation(GO:0019882)
0.1 0.2 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.1 0.9 GO:0033687 osteoblast proliferation(GO:0033687)
0.1 0.2 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.1 GO:0010273 regulation of oxidative phosphorylation(GO:0002082) detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.0 0.1 GO:0010107 potassium ion import(GO:0010107)
0.0 0.6 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.2 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.0 0.2 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.0 0.1 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.1 GO:0050955 thermoception(GO:0050955)
0.0 0.2 GO:0033089 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0 0.1 GO:0006562 proline catabolic process(GO:0006562)
0.0 0.1 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 0.1 GO:0071168 protein localization to chromatin(GO:0071168)
0.0 0.1 GO:0070842 aggresome assembly(GO:0070842)
0.0 1.2 GO:0006986 response to unfolded protein(GO:0006986)
0.0 0.0 GO:0060744 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.0 0.1 GO:0045116 protein neddylation(GO:0045116)
0.0 1.1 GO:0051592 response to calcium ion(GO:0051592)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0005726 perichromatin fibrils(GO:0005726)
0.3 1.0 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.2 5.8 GO:0042612 MHC class I protein complex(GO:0042612)
0.2 0.6 GO:0005607 laminin-2 complex(GO:0005607)
0.2 1.3 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 3.5 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 1.1 GO:0005577 fibrinogen complex(GO:0005577)
0.1 1.3 GO:0042627 chylomicron(GO:0042627)
0.0 5.9 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 1.0 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.1 GO:0005873 plus-end kinesin complex(GO:0005873)
0.0 0.1 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.5 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 1.4 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.2 GO:0030914 STAGA complex(GO:0030914)
0.0 1.2 GO:0005788 endoplasmic reticulum lumen(GO:0005788)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 5.6 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.4 2.9 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.4 1.5 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.3 1.1 GO:0042910 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.3 1.3 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.2 1.0 GO:0008112 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.2 1.2 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.2 2.1 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 1.3 GO:0034056 estrogen response element binding(GO:0034056)
0.1 0.7 GO:0042577 lipid phosphatase activity(GO:0042577)
0.1 1.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 1.0 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.1 1.0 GO:0034185 apolipoprotein binding(GO:0034185)
0.1 0.2 GO:0004797 thymidine kinase activity(GO:0004797)
0.1 0.5 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 0.6 GO:1901567 icosanoid binding(GO:0050542) arachidonic acid binding(GO:0050544) fatty acid derivative binding(GO:1901567)
0.1 0.4 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 1.6 GO:0004623 phospholipase A2 activity(GO:0004623)
0.1 0.2 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.1 0.7 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.1 1.7 GO:0005523 tropomyosin binding(GO:0005523)
0.1 5.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 1.1 GO:0043499 obsolete eukaryotic cell surface binding(GO:0043499)
0.0 2.3 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.2 GO:0017159 pantetheine hydrolase activity(GO:0017159) GPI anchor binding(GO:0034235)
0.0 0.1 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.0 0.1 GO:0016531 copper chaperone activity(GO:0016531)
0.0 0.1 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.1 GO:0008907 integrase activity(GO:0008907)
0.0 0.3 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.5 GO:0000049 tRNA binding(GO:0000049)
0.0 0.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.2 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, RNA polymerase II basal transcription factor binding(GO:0001083) transcription factor activity, TFIIB-class binding(GO:0001087) RNA polymerase II basal transcription factor binding(GO:0001091) TFIIB-class transcription factor binding(GO:0001093)
0.0 0.0 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.0 0.3 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.