Motif ID: PDX1

Z-value: 0.576


Transcription factors associated with PDX1:

Gene SymbolEntrez IDGene Name
PDX1 ENSG00000139515.5 PDX1



Activity profile for motif PDX1.

activity profile for motif PDX1


Sorted Z-values histogram for motif PDX1

Sorted Z-values for motif PDX1



Network of associatons between targets according to the STRING database.



First level regulatory network of PDX1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_116660246 0.768 ENST00000434836.1
ENST00000393443.1
ENST00000465133.1
ENST00000477742.1
ENST00000393447.4
ENST00000393444.3
ST7





suppression of tumorigenicity 7





chr13_-_46716969 0.694 ENST00000435666.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr1_+_198608146 0.560 ENST00000367376.2
ENST00000352140.3
ENST00000594404.1
ENST00000598951.1
ENST00000530727.1
ENST00000442510.2
ENST00000367367.4
ENST00000348564.6
ENST00000367364.1
ENST00000413409.2
PTPRC









protein tyrosine phosphatase, receptor type, C









chr6_-_32157947 0.543 ENST00000375050.4
PBX2
pre-B-cell leukemia homeobox 2
chr3_-_38071122 0.490 ENST00000334661.4
PLCD1
phospholipase C, delta 1
chr12_+_28410128 0.454 ENST00000381259.1
ENST00000381256.1
CCDC91

coiled-coil domain containing 91

chr3_-_141747950 0.451 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr6_+_150920999 0.445 ENST00000367328.1
ENST00000367326.1
PLEKHG1

pleckstrin homology domain containing, family G (with RhoGef domain) member 1

chr8_+_77593448 0.406 ENST00000521891.2
ZFHX4
zinc finger homeobox 4
chr6_+_13272904 0.359 ENST00000379335.3
ENST00000379329.1
PHACTR1

phosphatase and actin regulator 1

chr15_+_43985725 0.357 ENST00000413453.2
CKMT1A
creatine kinase, mitochondrial 1A
chr8_+_77593474 0.330 ENST00000455469.2
ENST00000050961.6
ZFHX4

zinc finger homeobox 4

chr21_-_15918618 0.319 ENST00000400564.1
ENST00000400566.1
SAMSN1

SAM domain, SH3 domain and nuclear localization signals 1

chr4_-_41884620 0.314 ENST00000504870.1
LINC00682
long intergenic non-protein coding RNA 682
chr15_+_43886057 0.305 ENST00000441322.1
ENST00000413657.2
ENST00000453733.1
CKMT1B


creatine kinase, mitochondrial 1B


chr8_+_50824233 0.296 ENST00000522124.1
SNTG1
syntrophin, gamma 1
chr13_-_67802549 0.293 ENST00000328454.5
ENST00000377865.2
PCDH9

protocadherin 9

chr15_-_55563072 0.288 ENST00000567380.1
ENST00000565972.1
ENST00000569493.1
RAB27A


RAB27A, member RAS oncogene family


chr12_+_81110684 0.283 ENST00000228644.3
MYF5
myogenic factor 5
chr18_+_55888767 0.276 ENST00000431212.2
ENST00000586268.1
ENST00000587190.1
NEDD4L


neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase


chr14_-_69261310 0.270 ENST00000336440.3
ZFP36L1
ZFP36 ring finger protein-like 1
chrX_-_110655306 0.246 ENST00000371993.2
DCX
doublecortin
chr21_-_35899113 0.236 ENST00000492600.1
ENST00000481448.1
ENST00000381132.2
RCAN1


regulator of calcineurin 1


chr18_+_29027696 0.225 ENST00000257189.4
DSG3
desmoglein 3
chr8_-_86290333 0.222 ENST00000521846.1
ENST00000523022.1
ENST00000524324.1
ENST00000519991.1
ENST00000520663.1
ENST00000517590.1
ENST00000522579.1
ENST00000522814.1
ENST00000522662.1
ENST00000523858.1
ENST00000519129.1
CA1










carbonic anhydrase I










chr15_-_55562479 0.215 ENST00000564609.1
RAB27A
RAB27A, member RAS oncogene family
chr5_-_134735568 0.215 ENST00000510038.1
ENST00000304332.4
H2AFY

H2A histone family, member Y

chr17_-_27418537 0.205 ENST00000408971.2
TIAF1
TGFB1-induced anti-apoptotic factor 1
chr7_+_50348268 0.200 ENST00000438033.1
ENST00000439701.1
IKZF1

IKAROS family zinc finger 1 (Ikaros)

chr17_+_72427477 0.199 ENST00000342648.5
ENST00000481232.1
GPRC5C

G protein-coupled receptor, family C, group 5, member C

chr14_+_22985251 0.198 ENST00000390510.1
TRAJ27
T cell receptor alpha joining 27
chr3_+_111718173 0.196 ENST00000494932.1
TAGLN3
transgelin 3
chr1_+_28261533 0.195 ENST00000411604.1
ENST00000373888.4
SMPDL3B

sphingomyelin phosphodiesterase, acid-like 3B

chr14_+_72052983 0.192 ENST00000358550.2
SIPA1L1
signal-induced proliferation-associated 1 like 1
chr3_+_69985734 0.191 ENST00000314557.6
ENST00000394351.3
MITF

microphthalmia-associated transcription factor

chr12_-_16761007 0.186 ENST00000354662.1
ENST00000441439.2
LMO3

LIM domain only 3 (rhombotin-like 2)

chr4_-_155533787 0.184 ENST00000407946.1
ENST00000405164.1
ENST00000336098.3
ENST00000393846.2
ENST00000404648.3
ENST00000443553.1
FGG





fibrinogen gamma chain





chr16_-_29910853 0.178 ENST00000308713.5
SEZ6L2
seizure related 6 homolog (mouse)-like 2
chr1_+_62439037 0.173 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr12_-_86650045 0.170 ENST00000604798.1
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr8_-_42234745 0.170 ENST00000220812.2
DKK4
dickkopf WNT signaling pathway inhibitor 4
chrX_-_20236970 0.169 ENST00000379548.4
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr12_-_86650077 0.166 ENST00000552808.2
ENST00000547225.1
MGAT4C

mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)

chr1_-_190446759 0.166 ENST00000367462.3
BRINP3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr4_-_116034979 0.166 ENST00000264363.2
NDST4
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4
chr12_-_52967600 0.166 ENST00000549343.1
ENST00000305620.2
KRT74

keratin 74

chr11_-_8290263 0.156 ENST00000428101.2
LMO1
LIM domain only 1 (rhombotin 1)
chr3_+_69985792 0.155 ENST00000531774.1
MITF
microphthalmia-associated transcription factor
chr20_+_52105495 0.153 ENST00000439873.2
AL354993.1
Cell growth-inhibiting protein 7; HCG1784586; Uncharacterized protein
chr11_-_115630900 0.153 ENST00000537070.1
ENST00000499809.1
ENST00000514294.2
ENST00000535683.1
LINC00900



long intergenic non-protein coding RNA 900



chr2_-_136678123 0.149 ENST00000422708.1
DARS
aspartyl-tRNA synthetase
chr4_+_144354644 0.141 ENST00000512843.1
GAB1
GRB2-associated binding protein 1
chr7_-_25268104 0.140 ENST00000222674.2
NPVF
neuropeptide VF precursor
chr1_-_1709845 0.138 ENST00000341426.5
ENST00000344463.4
NADK

NAD kinase

chr3_+_111718036 0.138 ENST00000455401.2
TAGLN3
transgelin 3
chr3_-_57233966 0.136 ENST00000473921.1
ENST00000295934.3
HESX1

HESX homeobox 1

chr1_+_199996702 0.134 ENST00000367362.3
NR5A2
nuclear receptor subfamily 5, group A, member 2
chr6_+_34204642 0.130 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
HMGA1




high mobility group AT-hook 1




chr2_-_166930131 0.130 ENST00000303395.4
ENST00000409050.1
ENST00000423058.2
ENST00000375405.3
SCN1A



sodium channel, voltage-gated, type I, alpha subunit



chr4_-_103749205 0.127 ENST00000508249.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr12_+_41831485 0.127 ENST00000539469.2
ENST00000298919.7
PDZRN4

PDZ domain containing ring finger 4

chr4_-_89978299 0.125 ENST00000511976.1
ENST00000509094.1
ENST00000264344.5
ENST00000515600.1
FAM13A



family with sequence similarity 13, member A



chr14_-_36988882 0.122 ENST00000498187.2
NKX2-1
NK2 homeobox 1
chr1_-_38019878 0.121 ENST00000296215.6
SNIP1
Smad nuclear interacting protein 1
chr16_-_30457048 0.119 ENST00000500504.2
ENST00000542752.1
SEPHS2

selenophosphate synthetase 2

chr13_-_41593425 0.119 ENST00000239882.3
ELF1
E74-like factor 1 (ets domain transcription factor)
chr1_+_68150744 0.118 ENST00000370986.4
ENST00000370985.3
GADD45A

growth arrest and DNA-damage-inducible, alpha

chr9_-_124990680 0.114 ENST00000541397.2
ENST00000560485.1
LHX6

LIM homeobox 6

chr3_-_112127981 0.114 ENST00000486726.2
RP11-231E6.1
RP11-231E6.1
chr1_+_101003687 0.113 ENST00000315033.4
GPR88
G protein-coupled receptor 88
chr13_-_28545276 0.107 ENST00000381020.7
CDX2
caudal type homeobox 2
chr15_+_93443419 0.106 ENST00000557381.1
ENST00000420239.2
CHD2

chromodomain helicase DNA binding protein 2

chr1_-_1710229 0.105 ENST00000341991.3
NADK
NAD kinase
chr20_+_62795827 0.104 ENST00000328439.1
ENST00000536311.1
MYT1

myelin transcription factor 1

chr4_-_66536196 0.104 ENST00000511294.1
EPHA5
EPH receptor A5
chr2_-_190927447 0.102 ENST00000260950.4
MSTN
myostatin
chr18_-_33709268 0.100 ENST00000269187.5
ENST00000590986.1
ENST00000440549.2
SLC39A6


solute carrier family 39 (zinc transporter), member 6


chr12_+_81101277 0.098 ENST00000228641.3
MYF6
myogenic factor 6 (herculin)
chr2_-_145277569 0.098 ENST00000303660.4
ZEB2
zinc finger E-box binding homeobox 2
chr1_-_212965104 0.097 ENST00000422588.2
ENST00000366975.6
ENST00000366977.3
ENST00000366976.1
NSL1



NSL1, MIS12 kinetochore complex component



chr6_-_109702885 0.096 ENST00000504373.1
CD164
CD164 molecule, sialomucin
chr4_-_123377880 0.096 ENST00000226730.4
IL2
interleukin 2
chr2_+_45168875 0.095 ENST00000260653.3
SIX3
SIX homeobox 3
chr15_-_65903407 0.092 ENST00000395644.4
ENST00000567744.1
ENST00000568573.1
ENST00000562830.1
ENST00000569491.1
ENST00000561769.1
VWA9





von Willebrand factor A domain containing 9





chr4_-_66536057 0.092 ENST00000273854.3
EPHA5
EPH receptor A5
chr4_-_103749179 0.091 ENST00000502690.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr3_+_108541545 0.088 ENST00000295756.6
TRAT1
T cell receptor associated transmembrane adaptor 1
chr1_+_50574585 0.088 ENST00000371824.1
ENST00000371823.4
ELAVL4

ELAV like neuron-specific RNA binding protein 4

chr16_+_6533729 0.086 ENST00000551752.1
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chrX_-_130423200 0.085 ENST00000361420.3
IGSF1
immunoglobulin superfamily, member 1
chr3_+_108541608 0.085 ENST00000426646.1
TRAT1
T cell receptor associated transmembrane adaptor 1
chr12_-_52828147 0.081 ENST00000252245.5
KRT75
keratin 75
chr10_+_119301928 0.080 ENST00000553456.3
EMX2
empty spiracles homeobox 2
chr14_-_61116168 0.080 ENST00000247182.6
SIX1
SIX homeobox 1
chr20_+_42984330 0.079 ENST00000316673.4
ENST00000609795.1
ENST00000457232.1
ENST00000609262.1
HNF4A



hepatocyte nuclear factor 4, alpha



chr3_+_111717600 0.079 ENST00000273368.4
TAGLN3
transgelin 3
chr5_-_140998616 0.079 ENST00000389054.3
ENST00000398562.2
ENST00000389057.5
ENST00000398566.3
ENST00000398557.4
ENST00000253811.6
DIAPH1





diaphanous-related formin 1





chr5_-_140998481 0.078 ENST00000518047.1
DIAPH1
diaphanous-related formin 1
chr3_-_101039402 0.076 ENST00000193391.7
IMPG2
interphotoreceptor matrix proteoglycan 2
chr3_+_111717511 0.075 ENST00000478951.1
ENST00000393917.2
TAGLN3

transgelin 3

chr14_+_100485712 0.074 ENST00000544450.2
EVL
Enah/Vasp-like
chr5_-_141249154 0.074 ENST00000357517.5
ENST00000536585.1
PCDH1

protocadherin 1

chr11_-_129062093 0.073 ENST00000310343.9
ARHGAP32
Rho GTPase activating protein 32
chr17_-_40337470 0.073 ENST00000293330.1
HCRT
hypocretin (orexin) neuropeptide precursor
chr5_-_142780280 0.072 ENST00000424646.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr20_+_30697298 0.072 ENST00000398022.2
TM9SF4
transmembrane 9 superfamily protein member 4
chr11_+_125034586 0.069 ENST00000298282.9
PKNOX2
PBX/knotted 1 homeobox 2
chr1_-_10532531 0.069 ENST00000377036.2
ENST00000377038.3
DFFA

DNA fragmentation factor, 45kDa, alpha polypeptide

chr6_+_45296391 0.067 ENST00000371436.6
ENST00000576263.1
RUNX2

runt-related transcription factor 2

chr18_+_28898052 0.067 ENST00000257192.4
DSG1
desmoglein 1
chr19_+_11071546 0.065 ENST00000358026.2
SMARCA4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
chr4_+_151503077 0.064 ENST00000317605.4
MAB21L2
mab-21-like 2 (C. elegans)
chr3_+_115342349 0.064 ENST00000393780.3
GAP43
growth associated protein 43
chr15_-_34875771 0.064 ENST00000267731.7
GOLGA8B
golgin A8 family, member B
chr12_-_53171128 0.063 ENST00000332411.2
KRT76
keratin 76
chr7_+_129015484 0.063 ENST00000490911.1
AHCYL2
adenosylhomocysteinase-like 2
chr18_+_3447572 0.063 ENST00000548489.2
TGIF1
TGFB-induced factor homeobox 1
chr4_-_39979576 0.062 ENST00000303538.8
ENST00000503396.1
PDS5A

PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)

chr3_-_167191814 0.062 ENST00000466903.1
ENST00000264677.4
SERPINI2

serpin peptidase inhibitor, clade I (pancpin), member 2

chr2_+_196313239 0.061 ENST00000413290.1
AC064834.1
AC064834.1
chr2_+_48541776 0.059 ENST00000413569.1
ENST00000340553.3
FOXN2

forkhead box N2

chr5_-_134871639 0.059 ENST00000314744.4
NEUROG1
neurogenin 1
chr15_+_62853562 0.057 ENST00000561311.1
TLN2
talin 2
chr1_-_13002348 0.057 ENST00000355096.2
PRAMEF6
PRAME family member 6
chr15_-_55562582 0.056 ENST00000396307.2
RAB27A
RAB27A, member RAS oncogene family
chr19_+_641178 0.055 ENST00000166133.3
FGF22
fibroblast growth factor 22
chr11_+_65554493 0.054 ENST00000335987.3
OVOL1
ovo-like zinc finger 1
chr17_-_6983594 0.053 ENST00000571664.1
ENST00000254868.4
CLEC10A

C-type lectin domain family 10, member A

chr11_-_8285405 0.052 ENST00000335790.3
ENST00000534484.1
LMO1

LIM domain only 1 (rhombotin 1)

chr6_+_29079668 0.052 ENST00000377169.1
OR2J3
olfactory receptor, family 2, subfamily J, member 3
chr12_+_49621658 0.051 ENST00000541364.1
TUBA1C
tubulin, alpha 1c
chr7_-_99717463 0.051 ENST00000437822.2
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr16_+_6533380 0.051 ENST00000552089.1
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr15_+_67841330 0.050 ENST00000354498.5
MAP2K5
mitogen-activated protein kinase kinase 5
chr2_-_61697862 0.050 ENST00000398571.2
USP34
ubiquitin specific peptidase 34
chr5_+_174151536 0.049 ENST00000239243.6
ENST00000507785.1
MSX2

msh homeobox 2

chr12_+_50144381 0.049 ENST00000552370.1
TMBIM6
transmembrane BAX inhibitor motif containing 6
chr13_-_99667960 0.049 ENST00000448493.2
DOCK9
dedicator of cytokinesis 9
chr11_-_115375107 0.047 ENST00000545380.1
ENST00000452722.3
ENST00000537058.1
ENST00000536727.1
ENST00000542447.2
ENST00000331581.6
CADM1





cell adhesion molecule 1





chr20_+_43029911 0.046 ENST00000443598.2
ENST00000316099.4
ENST00000415691.2
HNF4A


hepatocyte nuclear factor 4, alpha


chr4_-_53525406 0.046 ENST00000451218.2
ENST00000441222.3
USP46

ubiquitin specific peptidase 46

chr8_-_133123406 0.046 ENST00000434736.2
HHLA1
HERV-H LTR-associating 1
chr1_-_2458026 0.046 ENST00000435556.3
ENST00000378466.3
PANK4

pantothenate kinase 4

chr7_-_44229022 0.046 ENST00000403799.3
GCK
glucokinase (hexokinase 4)
chr17_-_46690839 0.040 ENST00000498634.2
HOXB8
homeobox B8
chr4_-_103748880 0.039 ENST00000453744.2
ENST00000349311.8
UBE2D3

ubiquitin-conjugating enzyme E2D 3

chr6_-_25042231 0.038 ENST00000510784.2
FAM65B
family with sequence similarity 65, member B
chr18_+_59000815 0.036 ENST00000262717.4
CDH20
cadherin 20, type 2
chr12_-_56106060 0.036 ENST00000452168.2
ITGA7
integrin, alpha 7
chr9_-_14722715 0.035 ENST00000380911.3
CER1
cerberus 1, DAN family BMP antagonist
chr7_+_100860949 0.034 ENST00000305105.2
ZNHIT1
zinc finger, HIT-type containing 1
chr17_-_6983550 0.034 ENST00000576617.1
ENST00000416562.2
CLEC10A

C-type lectin domain family 10, member A

chr6_-_38670897 0.033 ENST00000373365.4
GLO1
glyoxalase I
chr15_+_48498480 0.031 ENST00000380993.3
ENST00000396577.3
SLC12A1

solute carrier family 12 (sodium/potassium/chloride transporter), member 1

chr2_+_166152283 0.030 ENST00000375427.2
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr20_+_60174827 0.030 ENST00000543233.1
CDH4
cadherin 4, type 1, R-cadherin (retinal)
chr15_+_75080883 0.029 ENST00000567571.1
CSK
c-src tyrosine kinase
chr4_-_41750922 0.029 ENST00000226382.2
PHOX2B
paired-like homeobox 2b
chr1_+_159272111 0.027 ENST00000368114.1
FCER1A
Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
chr12_-_51611477 0.024 ENST00000389243.4
POU6F1
POU class 6 homeobox 1
chr15_+_34261089 0.022 ENST00000383263.5
CHRM5
cholinergic receptor, muscarinic 5
chr5_+_169532896 0.022 ENST00000306268.6
ENST00000449804.2
FOXI1

forkhead box I1

chr6_-_100912785 0.022 ENST00000369208.3
SIM1
single-minded family bHLH transcription factor 1
chr3_+_35722487 0.021 ENST00000441454.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chrX_-_13835147 0.021 ENST00000493677.1
ENST00000355135.2
GPM6B

glycoprotein M6B

chr6_-_33160231 0.018 ENST00000395194.1
ENST00000457788.1
ENST00000341947.2
ENST00000357486.1
ENST00000374714.1
ENST00000374713.1
ENST00000395197.1
ENST00000374712.1
ENST00000361917.1
ENST00000374708.4
COL11A2









collagen, type XI, alpha 2









chrX_-_100129128 0.018 ENST00000372960.4
ENST00000372964.1
ENST00000217885.5
NOX1


NADPH oxidase 1


chr17_-_9929581 0.018 ENST00000437099.2
ENST00000396115.2
GAS7

growth arrest-specific 7

chr15_+_58430368 0.016 ENST00000558772.1
ENST00000219919.4
AQP9

aquaporin 9

chr7_-_151217001 0.015 ENST00000262187.5
RHEB
Ras homolog enriched in brain
chr6_-_87804815 0.014 ENST00000369582.2
CGA
glycoprotein hormones, alpha polypeptide
chr15_+_58430567 0.014 ENST00000536493.1
AQP9
aquaporin 9
chr1_+_45241109 0.013 ENST00000396651.3
RPS8
ribosomal protein S8
chr11_-_36619771 0.012 ENST00000311485.3
ENST00000527033.1
ENST00000532616.1
RAG2


recombination activating gene 2


chr5_-_9630463 0.012 ENST00000382492.2
TAS2R1
taste receptor, type 2, member 1
chr17_+_60536002 0.012 ENST00000582809.1
TLK2
tousled-like kinase 2
chr3_-_108248169 0.012 ENST00000273353.3
MYH15
myosin, heavy chain 15
chr15_-_31393910 0.011 ENST00000397795.2
ENST00000256552.6
ENST00000559179.1
TRPM1


transient receptor potential cation channel, subfamily M, member 1


chrX_+_144908928 0.009 ENST00000408967.2
TMEM257
transmembrane protein 257
chr4_-_119759795 0.008 ENST00000419654.2
SEC24D
SEC24 family member D
chr12_+_15699286 0.006 ENST00000442921.2
ENST00000542557.1
ENST00000445537.2
ENST00000544244.1
PTPRO



protein tyrosine phosphatase, receptor type, O



chr15_-_72563585 0.006 ENST00000287196.9
ENST00000260376.7
PARP6

poly (ADP-ribose) polymerase family, member 6

chr10_-_1779663 0.006 ENST00000381312.1
ADARB2
adenosine deaminase, RNA-specific, B2 (non-functional)
chr7_-_14028488 0.006 ENST00000405358.4
ETV1
ets variant 1
chr2_+_109204743 0.005 ENST00000332345.6
LIMS1
LIM and senescent cell antigen-like domains 1
chr4_-_103749313 0.005 ENST00000394803.5
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr10_+_114710425 0.004 ENST00000352065.5
ENST00000369395.1
TCF7L2

transcription factor 7-like 2 (T-cell specific, HMG-box)

chr10_-_48416849 0.003 ENST00000249598.1
GDF2
growth differentiation factor 2
chr3_+_149191723 0.003 ENST00000305354.4
TM4SF4
transmembrane 4 L six family member 4
chr6_-_111136513 0.001 ENST00000368911.3
CDK19
cyclin-dependent kinase 19
chr11_-_102496063 0.001 ENST00000260228.2
MMP20
matrix metallopeptidase 20

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.1 0.6 GO:0043316 natural killer cell activation involved in immune response(GO:0002323) cytotoxic T cell degranulation(GO:0043316) natural killer cell degranulation(GO:0043320)
0.0 0.4 GO:0042693 muscle cell fate commitment(GO:0042693)
0.0 0.3 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.1 GO:0014889 muscle atrophy(GO:0014889) regulation of skeletal muscle tissue growth(GO:0048631)
0.0 0.1 GO:0045591 positive regulation of regulatory T cell differentiation(GO:0045591)
0.0 0.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.1 GO:0060398 regulation of growth hormone receptor signaling pathway(GO:0060398)
0.0 0.2 GO:0007549 dosage compensation(GO:0007549)
0.0 0.1 GO:0021759 globus pallidus development(GO:0021759) menarche(GO:0042696)
0.0 0.3 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.1 GO:0051451 myoblast migration(GO:0051451)
0.0 0.1 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.2 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0 0.1 GO:0051971 positive regulation of transmission of nerve impulse(GO:0051971)
0.0 0.1 GO:0021877 forebrain neuron fate commitment(GO:0021877)
0.0 0.2 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.2 GO:0097061 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0 0.1 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.5 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.2 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.7 GO:0002286 T cell activation involved in immune response(GO:0002286)
0.0 0.1 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.2 GO:0071599 otic vesicle formation(GO:0030916) otic vesicle development(GO:0071599) otic vesicle morphogenesis(GO:0071600)
0.0 0.0 GO:0002331 immature B cell differentiation(GO:0002327) pre-B cell differentiation(GO:0002329) pre-B cell allelic exclusion(GO:0002331)
0.0 0.0 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.0 GO:0044321 cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
0.0 0.1 GO:0002051 osteoblast fate commitment(GO:0002051)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.2 GO:0001740 Barr body(GO:0001740)
0.0 0.1 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.1 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.3 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.3 GO:0030057 desmosome(GO:0030057)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 0.6 GO:0031489 myosin V binding(GO:0031489)
0.1 0.3 GO:0004111 creatine kinase activity(GO:0004111)
0.1 0.2 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.3 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.3 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.1 GO:0004756 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.1 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.2 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.4 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.6 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0034711 inhibin binding(GO:0034711)
0.0 0.1 GO:0004883 glucocorticoid receptor activity(GO:0004883)
0.0 0.4 GO:0070888 E-box binding(GO:0070888)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.0 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0001228 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.4 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 SIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes