Motif ID: PGR
Z-value: 1.389
Transcription factors associated with PGR:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| PGR | ENSG00000082175.10 | PGR |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 1.0 | GO:0031034 | skeletal muscle myosin thick filament assembly(GO:0030241) myosin filament assembly(GO:0031034) striated muscle myosin thick filament assembly(GO:0071688) |
| 0.3 | 0.5 | GO:0048739 | cardiac muscle fiber development(GO:0048739) |
| 0.2 | 0.7 | GO:0051451 | myoblast migration(GO:0051451) |
| 0.2 | 0.5 | GO:0033578 | protein glycosylation in Golgi(GO:0033578) |
| 0.2 | 1.8 | GO:0006030 | chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032) |
| 0.2 | 0.6 | GO:0051573 | negative regulation of histone H3-K9 methylation(GO:0051573) |
| 0.1 | 0.7 | GO:0090050 | positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672) |
| 0.1 | 0.4 | GO:0071848 | regulation of fever generation by regulation of prostaglandin secretion(GO:0071810) positive regulation of fever generation by positive regulation of prostaglandin secretion(GO:0071812) TNFSF11-mediated signaling pathway(GO:0071847) positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling(GO:0071848) regulation of fever generation by prostaglandin secretion(GO:0100009) |
| 0.1 | 3.4 | GO:0030199 | collagen fibril organization(GO:0030199) |
| 0.1 | 1.0 | GO:0030422 | production of siRNA involved in RNA interference(GO:0030422) |
| 0.1 | 3.9 | GO:0006942 | regulation of striated muscle contraction(GO:0006942) |
| 0.1 | 0.2 | GO:0033043 | regulation of organelle organization(GO:0033043) regulation of cytoskeleton organization(GO:0051493) |
| 0.1 | 0.3 | GO:1901522 | positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522) |
| 0.1 | 0.2 | GO:0071280 | epithelial fluid transport(GO:0042045) cellular response to copper ion(GO:0071280) |
| 0.1 | 0.9 | GO:0042832 | defense response to protozoan(GO:0042832) |
| 0.1 | 1.8 | GO:0002504 | antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504) |
| 0.1 | 0.3 | GO:0061302 | smooth muscle cell-matrix adhesion(GO:0061302) |
| 0.1 | 0.2 | GO:0061084 | regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084) negative regulation of protein folding(GO:1903333) |
| 0.1 | 1.2 | GO:0032781 | positive regulation of ATPase activity(GO:0032781) |
| 0.1 | 0.3 | GO:0043116 | negative regulation of vascular permeability(GO:0043116) |
| 0.1 | 5.3 | GO:0007229 | integrin-mediated signaling pathway(GO:0007229) |
| 0.1 | 0.3 | GO:0007100 | mitotic centrosome separation(GO:0007100) |
| 0.1 | 0.3 | GO:0007352 | zygotic specification of dorsal/ventral axis(GO:0007352) |
| 0.1 | 1.2 | GO:0000303 | response to superoxide(GO:0000303) |
| 0.0 | 0.0 | GO:0046639 | negative regulation of alpha-beta T cell differentiation(GO:0046639) |
| 0.0 | 0.8 | GO:0016601 | Rac protein signal transduction(GO:0016601) |
| 0.0 | 0.9 | GO:0030889 | negative regulation of B cell proliferation(GO:0030889) |
| 0.0 | 0.1 | GO:0060596 | mammary placode formation(GO:0060596) |
| 0.0 | 0.2 | GO:0050957 | equilibrioception(GO:0050957) |
| 0.0 | 0.1 | GO:0006668 | sphinganine-1-phosphate metabolic process(GO:0006668) |
| 0.0 | 0.7 | GO:0075713 | establishment of viral latency(GO:0019043) establishment of integrated proviral latency(GO:0075713) |
| 0.0 | 1.8 | GO:0007585 | respiratory gaseous exchange(GO:0007585) |
| 0.0 | 3.4 | GO:0007498 | mesoderm development(GO:0007498) |
| 0.0 | 0.3 | GO:0032647 | interferon-alpha production(GO:0032607) regulation of interferon-alpha production(GO:0032647) positive regulation of interferon-alpha production(GO:0032727) |
| 0.0 | 0.4 | GO:0014037 | Schwann cell differentiation(GO:0014037) |
| 0.0 | 0.1 | GO:0021978 | telencephalon regionalization(GO:0021978) |
| 0.0 | 0.2 | GO:0007141 | male meiosis I(GO:0007141) |
| 0.0 | 1.2 | GO:0006941 | striated muscle contraction(GO:0006941) |
| 0.0 | 0.1 | GO:0021529 | spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780) |
| 0.0 | 1.8 | GO:0006986 | response to unfolded protein(GO:0006986) |
| 0.0 | 0.1 | GO:0060397 | JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397) |
| 0.0 | 0.5 | GO:0009954 | proximal/distal pattern formation(GO:0009954) |
| 0.0 | 0.1 | GO:0071918 | urea transmembrane transport(GO:0071918) |
| 0.0 | 0.6 | GO:0002286 | T cell activation involved in immune response(GO:0002286) |
| 0.0 | 0.7 | GO:0030049 | muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275) |
| 0.0 | 0.1 | GO:0030432 | peristalsis(GO:0030432) |
| 0.0 | 0.1 | GO:1902414 | protein localization to adherens junction(GO:0071896) protein localization to cell junction(GO:1902414) |
| 0.0 | 0.0 | GO:0035054 | embryonic heart tube anterior/posterior pattern specification(GO:0035054) embryonic foregut morphogenesis(GO:0048617) |
| 0.0 | 0.1 | GO:0060259 | regulation of feeding behavior(GO:0060259) |
| 0.0 | 0.5 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
| 0.0 | 0.3 | GO:0050832 | defense response to fungus(GO:0050832) |
| 0.0 | 0.4 | GO:0045646 | regulation of erythrocyte differentiation(GO:0045646) |
| 0.0 | 0.1 | GO:0033137 | negative regulation of peptidyl-serine phosphorylation(GO:0033137) |
| 0.0 | 0.0 | GO:0000114 | obsolete regulation of transcription involved in G1 phase of mitotic cell cycle(GO:0000114) |
| 0.0 | 0.5 | GO:0007602 | phototransduction(GO:0007602) |
| 0.0 | 0.3 | GO:0043968 | histone H2A acetylation(GO:0043968) |
| 0.0 | 0.1 | GO:0061099 | negative regulation of protein tyrosine kinase activity(GO:0061099) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 0.9 | GO:0005588 | collagen type V trimer(GO:0005588) |
| 0.2 | 2.1 | GO:0031430 | M band(GO:0031430) |
| 0.2 | 1.7 | GO:0098643 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
| 0.2 | 3.9 | GO:0005861 | troponin complex(GO:0005861) |
| 0.1 | 0.3 | GO:0071062 | alphav-beta3 integrin-vitronectin complex(GO:0071062) |
| 0.1 | 5.3 | GO:0098636 | integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636) |
| 0.1 | 0.6 | GO:0001891 | phagocytic cup(GO:0001891) |
| 0.1 | 1.8 | GO:0042613 | MHC class II protein complex(GO:0042613) |
| 0.1 | 0.2 | GO:0033655 | host(GO:0018995) host cell cytoplasm(GO:0030430) host cell part(GO:0033643) host intracellular part(GO:0033646) host cell cytoplasm part(GO:0033655) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217) |
| 0.1 | 0.9 | GO:0031672 | A band(GO:0031672) |
| 0.1 | 0.3 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
| 0.1 | 0.2 | GO:0000800 | lateral element(GO:0000800) |
| 0.0 | 0.3 | GO:0045179 | apical cortex(GO:0045179) |
| 0.0 | 0.2 | GO:0005896 | interleukin-6 receptor complex(GO:0005896) |
| 0.0 | 0.9 | GO:0071564 | npBAF complex(GO:0071564) |
| 0.0 | 0.5 | GO:0032982 | myosin filament(GO:0032982) |
| 0.0 | 0.3 | GO:0016585 | obsolete chromatin remodeling complex(GO:0016585) |
| 0.0 | 0.4 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
| 0.0 | 0.4 | GO:0033116 | endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116) |
| 0.0 | 0.8 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.0 | 0.8 | GO:0030141 | secretory granule(GO:0030141) |
| 0.0 | 0.1 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.0 | 0.1 | GO:0016461 | unconventional myosin complex(GO:0016461) |
| 0.0 | 0.2 | GO:0032420 | stereocilium(GO:0032420) |
| 0.0 | 0.4 | GO:0016328 | lateral plasma membrane(GO:0016328) |
| 0.0 | 0.3 | GO:0016010 | dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 1.8 | GO:0097493 | extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493) |
| 0.3 | 1.0 | GO:0004504 | peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598) |
| 0.2 | 0.9 | GO:0032038 | myosin II heavy chain binding(GO:0032038) |
| 0.2 | 0.5 | GO:0008424 | glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921) |
| 0.2 | 1.8 | GO:0004568 | chitinase activity(GO:0004568) |
| 0.1 | 3.7 | GO:0005523 | tropomyosin binding(GO:0005523) |
| 0.1 | 0.5 | GO:0030899 | calcium-dependent ATPase activity(GO:0030899) |
| 0.1 | 1.0 | GO:0051393 | alpha-actinin binding(GO:0051393) |
| 0.1 | 0.4 | GO:0005534 | galactose binding(GO:0005534) |
| 0.1 | 0.2 | GO:0032564 | dATP binding(GO:0032564) |
| 0.1 | 0.8 | GO:0016641 | oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641) |
| 0.1 | 0.2 | GO:0005223 | intracellular cGMP activated cation channel activity(GO:0005223) |
| 0.0 | 0.1 | GO:0017040 | ceramidase activity(GO:0017040) |
| 0.0 | 0.9 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 0.0 | 0.1 | GO:0004865 | protein serine/threonine phosphatase inhibitor activity(GO:0004865) |
| 0.0 | 0.3 | GO:0002162 | dystroglycan binding(GO:0002162) |
| 0.0 | 0.5 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
| 0.0 | 0.2 | GO:0016312 | inositol bisphosphate phosphatase activity(GO:0016312) |
| 0.0 | 0.0 | GO:0005113 | patched binding(GO:0005113) |
| 0.0 | 0.2 | GO:0008158 | hedgehog receptor activity(GO:0008158) |
| 0.0 | 0.4 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |
| 0.0 | 0.3 | GO:0030247 | pattern binding(GO:0001871) polysaccharide binding(GO:0030247) |
| 0.0 | 0.2 | GO:0005138 | interleukin-6 receptor binding(GO:0005138) |
| 0.0 | 1.0 | GO:0003725 | double-stranded RNA binding(GO:0003725) |
| 0.0 | 0.1 | GO:0042392 | sphingosine-1-phosphate phosphatase activity(GO:0042392) |
| 0.0 | 0.1 | GO:0030292 | protein tyrosine kinase inhibitor activity(GO:0030292) |
| 0.0 | 0.1 | GO:0003828 | alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828) |
| 0.0 | 1.5 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.0 | 0.1 | GO:0015204 | urea transmembrane transporter activity(GO:0015204) |
| 0.0 | 1.4 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
| 0.0 | 0.8 | GO:0003823 | antigen binding(GO:0003823) |
| 0.0 | 0.3 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.0 | 0.4 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
| 0.0 | 0.1 | GO:0004982 | N-formyl peptide receptor activity(GO:0004982) |
| 0.0 | 0.2 | GO:0016922 | ligand-dependent nuclear receptor binding(GO:0016922) |
| 0.0 | 0.2 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.0 | 0.1 | GO:0003840 | gamma-glutamyltransferase activity(GO:0003840) |
| 0.0 | 0.1 | GO:0035381 | extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | ST_STAT3_PATHWAY | STAT3 Pathway |
| 0.0 | 0.6 | ST_GA12_PATHWAY | G alpha 12 Pathway |
