Motif ID: POU1F1
Z-value: 0.924
Transcription factors associated with POU1F1:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| POU1F1 | ENSG00000064835.6 | POU1F1 |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 2.9 | GO:0007499 | ectoderm and mesoderm interaction(GO:0007499) |
| 0.2 | 0.9 | GO:0043128 | regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128) |
| 0.2 | 0.8 | GO:0019371 | cyclooxygenase pathway(GO:0019371) |
| 0.1 | 0.7 | GO:0048669 | collateral sprouting in absence of injury(GO:0048669) |
| 0.1 | 0.5 | GO:0045356 | positive regulation of interferon-alpha biosynthetic process(GO:0045356) |
| 0.1 | 0.6 | GO:0007614 | short-term memory(GO:0007614) |
| 0.1 | 3.5 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.1 | 0.3 | GO:0006428 | isoleucyl-tRNA aminoacylation(GO:0006428) |
| 0.1 | 0.3 | GO:0051097 | negative regulation of helicase activity(GO:0051097) cellular response to exogenous dsRNA(GO:0071360) |
| 0.1 | 1.3 | GO:0060391 | positive regulation of SMAD protein import into nucleus(GO:0060391) |
| 0.1 | 1.0 | GO:1901797 | negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797) |
| 0.1 | 0.6 | GO:0006553 | lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554) |
| 0.1 | 0.6 | GO:0060586 | multicellular organismal iron ion homeostasis(GO:0060586) |
| 0.1 | 0.8 | GO:0014912 | negative regulation of smooth muscle cell migration(GO:0014912) positive regulation of myoblast differentiation(GO:0045663) |
| 0.1 | 0.2 | GO:0046604 | regulation of mitotic centrosome separation(GO:0046602) positive regulation of mitotic centrosome separation(GO:0046604) |
| 0.1 | 0.4 | GO:0006264 | mitochondrial DNA replication(GO:0006264) |
| 0.1 | 0.2 | GO:0070857 | regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251) |
| 0.1 | 0.6 | GO:0050435 | beta-amyloid metabolic process(GO:0050435) |
| 0.1 | 0.5 | GO:0040037 | negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037) |
| 0.0 | 0.3 | GO:0042420 | dopamine catabolic process(GO:0042420) |
| 0.0 | 0.3 | GO:0001514 | selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451) |
| 0.0 | 0.3 | GO:0044413 | evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834) |
| 0.0 | 1.0 | GO:0045103 | intermediate filament-based process(GO:0045103) |
| 0.0 | 0.1 | GO:0071277 | cellular response to calcium ion(GO:0071277) |
| 0.0 | 0.1 | GO:1902414 | protein localization to adherens junction(GO:0071896) protein localization to cell junction(GO:1902414) |
| 0.0 | 0.9 | GO:0030199 | collagen fibril organization(GO:0030199) |
| 0.0 | 0.6 | GO:0070206 | protein trimerization(GO:0070206) |
| 0.0 | 0.2 | GO:0043162 | ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162) |
| 0.0 | 0.2 | GO:0009441 | glycolate metabolic process(GO:0009441) |
| 0.0 | 0.1 | GO:0046520 | diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520) |
| 0.0 | 0.8 | GO:0006693 | prostaglandin metabolic process(GO:0006693) |
| 0.0 | 0.1 | GO:0034498 | early endosome to Golgi transport(GO:0034498) |
| 0.0 | 1.7 | GO:0007498 | mesoderm development(GO:0007498) |
| 0.0 | 0.1 | GO:0070254 | mucus secretion(GO:0070254) |
| 0.0 | 1.1 | GO:0060271 | cilium morphogenesis(GO:0060271) |
| 0.0 | 0.7 | GO:0007026 | negative regulation of microtubule depolymerization(GO:0007026) |
| 0.0 | 0.3 | GO:0009312 | oligosaccharide biosynthetic process(GO:0009312) |
| 0.0 | 1.9 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
| 0.0 | 1.4 | GO:0016573 | histone acetylation(GO:0016573) |
| 0.0 | 0.1 | GO:0007144 | female meiosis I(GO:0007144) |
| 0.0 | 0.1 | GO:0008053 | mitochondrial fusion(GO:0008053) |
| 0.0 | 0.3 | GO:0046580 | negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 1.0 | GO:0005588 | collagen type V trimer(GO:0005588) |
| 0.2 | 3.5 | GO:0005606 | laminin-1 complex(GO:0005606) |
| 0.1 | 0.7 | GO:0051233 | spindle midzone(GO:0051233) |
| 0.1 | 0.8 | GO:0016942 | insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) |
| 0.0 | 1.1 | GO:0016010 | dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665) |
| 0.0 | 0.7 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
| 0.0 | 0.8 | GO:0030057 | desmosome(GO:0030057) |
| 0.0 | 3.1 | GO:0030027 | lamellipodium(GO:0030027) |
| 0.0 | 0.1 | GO:0035145 | exon-exon junction complex(GO:0035145) |
| 0.0 | 1.5 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.0 | 0.2 | GO:0005868 | cytoplasmic dynein complex(GO:0005868) |
| 0.0 | 0.6 | GO:0045178 | basal part of cell(GO:0045178) |
| 0.0 | 0.7 | GO:0015030 | Cajal body(GO:0015030) |
| 0.0 | 0.2 | GO:0032420 | stereocilium(GO:0032420) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 0.8 | GO:0047718 | indanol dehydrogenase activity(GO:0047718) |
| 0.2 | 1.4 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
| 0.2 | 0.8 | GO:0008160 | protein tyrosine phosphatase activator activity(GO:0008160) protein phosphatase activator activity(GO:0072542) |
| 0.2 | 0.6 | GO:0016524 | latrotoxin receptor activity(GO:0016524) |
| 0.2 | 0.8 | GO:0004666 | prostaglandin-endoperoxide synthase activity(GO:0004666) |
| 0.1 | 0.4 | GO:0004797 | thymidine kinase activity(GO:0004797) |
| 0.1 | 0.3 | GO:0004822 | isoleucine-tRNA ligase activity(GO:0004822) |
| 0.1 | 0.3 | GO:0047273 | galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273) |
| 0.1 | 0.4 | GO:0004692 | cGMP-dependent protein kinase activity(GO:0004692) |
| 0.1 | 0.7 | GO:0033130 | acetylcholine receptor binding(GO:0033130) |
| 0.1 | 1.7 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.1 | 0.3 | GO:0008131 | primary amine oxidase activity(GO:0008131) |
| 0.1 | 1.3 | GO:0008143 | poly(A) binding(GO:0008143) |
| 0.0 | 0.6 | GO:0008242 | omega peptidase activity(GO:0008242) |
| 0.0 | 0.3 | GO:0004800 | thyroxine 5'-deiodinase activity(GO:0004800) |
| 0.0 | 1.4 | GO:0005523 | tropomyosin binding(GO:0005523) |
| 0.0 | 0.6 | GO:0004029 | aldehyde dehydrogenase (NAD) activity(GO:0004029) |
| 0.0 | 0.3 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
| 0.0 | 0.7 | GO:0043236 | laminin binding(GO:0043236) |
| 0.0 | 1.0 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.0 | 0.3 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
| 0.0 | 0.2 | GO:0002162 | dystroglycan binding(GO:0002162) |
| 0.0 | 0.2 | GO:0008454 | alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454) |
| 0.0 | 0.2 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) bicarbonate transmembrane transporter activity(GO:0015106) |
| 0.0 | 0.2 | GO:0008379 | thioredoxin peroxidase activity(GO:0008379) |
| 0.0 | 0.6 | GO:0008373 | sialyltransferase activity(GO:0008373) |
| 0.0 | 0.3 | GO:0004065 | arylsulfatase activity(GO:0004065) |
| 0.0 | 0.5 | GO:0005001 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
| 0.0 | 0.6 | GO:0004364 | glutathione transferase activity(GO:0004364) |
| 0.0 | 0.1 | GO:0004977 | melanocortin receptor activity(GO:0004977) |
| 0.0 | 1.0 | GO:0046332 | SMAD binding(GO:0046332) |
| 0.0 | 0.1 | GO:0008527 | taste receptor activity(GO:0008527) |
| 0.0 | 0.1 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
| 0.0 | 0.1 | GO:0005314 | high-affinity glutamate transmembrane transporter activity(GO:0005314) |
| 0.0 | 0.2 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
| 0.0 | 0.2 | GO:0010181 | FMN binding(GO:0010181) |
| 0.0 | 0.0 | GO:0005324 | long-chain fatty acid transporter activity(GO:0005324) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.0 | SA_MMP_CYTOKINE_CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 0.0 | 0.3 | ST_INTERLEUKIN_4_PATHWAY | Interleukin 4 (IL-4) Pathway |
| 0.0 | 1.1 | SIG_BCR_SIGNALING_PATHWAY | Members of the BCR signaling pathway |
| 0.0 | 0.6 | SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES | Genes related to regulation of the actin cytoskeleton |
