Motif ID: POU2F1
Z-value: 0.736
Transcription factors associated with POU2F1:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| POU2F1 | ENSG00000143190.17 | POU2F1 |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 1.4 | GO:0035630 | glycolate metabolic process(GO:0009441) bone mineralization involved in bone maturation(GO:0035630) |
| 0.1 | 0.4 | GO:0034310 | ethanol catabolic process(GO:0006068) fatty acid omega-oxidation(GO:0010430) primary alcohol catabolic process(GO:0034310) |
| 0.1 | 0.3 | GO:1901522 | positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522) |
| 0.1 | 0.6 | GO:0043316 | natural killer cell activation involved in immune response(GO:0002323) cytotoxic T cell degranulation(GO:0043316) natural killer cell degranulation(GO:0043320) |
| 0.1 | 2.0 | GO:0030889 | negative regulation of B cell proliferation(GO:0030889) |
| 0.1 | 1.0 | GO:0006600 | creatine metabolic process(GO:0006600) |
| 0.1 | 0.3 | GO:0046080 | dUTP metabolic process(GO:0046080) |
| 0.0 | 1.1 | GO:0042531 | positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531) |
| 0.0 | 0.1 | GO:0006106 | fumarate metabolic process(GO:0006106) |
| 0.0 | 0.2 | GO:0018343 | protein farnesylation(GO:0018343) |
| 0.0 | 0.2 | GO:0043615 | astrocyte cell migration(GO:0043615) |
| 0.0 | 0.2 | GO:0006003 | fructose 2,6-bisphosphate metabolic process(GO:0006003) |
| 0.0 | 0.2 | GO:0045059 | positive thymic T cell selection(GO:0045059) |
| 0.0 | 0.9 | GO:0006309 | DNA catabolic process, endonucleolytic(GO:0000737) apoptotic DNA fragmentation(GO:0006309) |
| 0.0 | 0.2 | GO:0010459 | negative regulation of heart rate(GO:0010459) |
| 0.0 | 1.1 | GO:0045576 | mast cell activation(GO:0045576) |
| 0.0 | 0.1 | GO:0040016 | embryonic cleavage(GO:0040016) |
| 0.0 | 0.3 | GO:0032876 | regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023) |
| 0.0 | 0.3 | GO:0001539 | cilium or flagellum-dependent cell motility(GO:0001539) |
| 0.0 | 0.1 | GO:0000114 | obsolete regulation of transcription involved in G1 phase of mitotic cell cycle(GO:0000114) |
| 0.0 | 0.1 | GO:0090292 | nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292) |
| 0.0 | 0.1 | GO:0042693 | muscle cell fate commitment(GO:0042693) |
| 0.0 | 0.0 | GO:1901419 | regulation of response to alcohol(GO:1901419) |
| 0.0 | 0.3 | GO:0006825 | copper ion transport(GO:0006825) |
| 0.0 | 0.5 | GO:0000080 | mitotic G1 phase(GO:0000080) |
| 0.0 | 0.0 | GO:0002689 | negative regulation of leukocyte chemotaxis(GO:0002689) |
| 0.0 | 1.1 | GO:0050680 | negative regulation of epithelial cell proliferation(GO:0050680) |
| 0.0 | 0.9 | GO:0061025 | membrane fusion(GO:0061025) |
| 0.0 | 0.1 | GO:0030578 | nuclear body organization(GO:0030575) PML body organization(GO:0030578) |
| 0.0 | 0.1 | GO:0043438 | acetoacetic acid metabolic process(GO:0043438) |
| 0.0 | 0.2 | GO:0042391 | regulation of membrane potential(GO:0042391) |
| 0.0 | 0.0 | GO:0072369 | positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716) regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 1.4 | GO:0016942 | insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) |
| 0.1 | 1.1 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
| 0.0 | 0.2 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 0.0 | 0.2 | GO:0097651 | phosphatidylinositol 3-kinase complex, class IA(GO:0005943) phosphatidylinositol 3-kinase complex, class I(GO:0097651) |
| 0.0 | 0.4 | GO:0005858 | axonemal dynein complex(GO:0005858) axoneme part(GO:0044447) |
| 0.0 | 2.4 | GO:0016363 | nuclear matrix(GO:0016363) |
| 0.0 | 0.2 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 0.0 | 0.1 | GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex(GO:0031464) |
| 0.0 | 1.0 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 0.0 | 0.1 | GO:0034993 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
| 0.0 | 0.2 | GO:0000808 | origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664) |
| 0.0 | 0.1 | GO:0045239 | tricarboxylic acid cycle enzyme complex(GO:0045239) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.2 | GO:0004522 | ribonuclease A activity(GO:0004522) |
| 0.1 | 0.4 | GO:0035276 | ethanol binding(GO:0035276) |
| 0.1 | 0.3 | GO:0004170 | dUTP diphosphatase activity(GO:0004170) |
| 0.1 | 0.6 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.1 | 0.3 | GO:0016724 | ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724) |
| 0.1 | 0.9 | GO:0016888 | endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888) |
| 0.1 | 0.4 | GO:0008649 | rRNA methyltransferase activity(GO:0008649) |
| 0.0 | 1.6 | GO:0005159 | insulin-like growth factor receptor binding(GO:0005159) |
| 0.0 | 0.2 | GO:0004660 | protein farnesyltransferase activity(GO:0004660) |
| 0.0 | 0.2 | GO:0051766 | inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766) |
| 0.0 | 0.2 | GO:0015562 | efflux transmembrane transporter activity(GO:0015562) |
| 0.0 | 0.1 | GO:0061505 | DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505) |
| 0.0 | 0.2 | GO:0003873 | 6-phosphofructo-2-kinase activity(GO:0003873) |
| 0.0 | 0.4 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, RNA polymerase II basal transcription factor binding(GO:0001083) transcription factor activity, TFIIB-class binding(GO:0001087) RNA polymerase II basal transcription factor binding(GO:0001091) TFIIB-class transcription factor binding(GO:0001093) |
| 0.0 | 1.0 | GO:0016769 | transferase activity, transferring nitrogenous groups(GO:0016769) |
| 0.0 | 0.3 | GO:0060590 | ATPase regulator activity(GO:0060590) |
| 0.0 | 2.4 | GO:0016566 | obsolete specific transcriptional repressor activity(GO:0016566) |
| 0.0 | 0.1 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
| 0.0 | 1.1 | GO:0003823 | antigen binding(GO:0003823) |
| 0.0 | 0.1 | GO:0031432 | titin binding(GO:0031432) |
| 0.0 | 0.1 | GO:0034711 | inhibin binding(GO:0034711) |
| 0.0 | 0.2 | GO:0003688 | DNA replication origin binding(GO:0003688) |
| 0.0 | 0.0 | GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159) |
| 0.0 | 0.1 | GO:0004176 | ATP-dependent peptidase activity(GO:0004176) |
| 0.0 | 0.1 | GO:0070053 | thrombospondin receptor activity(GO:0070053) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | ST_PAC1_RECEPTOR_PATHWAY | PAC1 Receptor Pathway |
| 0.0 | 1.7 | SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES | Genes related to PIP3 signaling in cardiac myocytes |
