Motif ID: POU2F2_POU3F1

Z-value: 4.001

Transcription factors associated with POU2F2_POU3F1:

Gene SymbolEntrez IDGene Name
POU2F2 ENSG00000028277.16 POU2F2
POU3F1 ENSG00000185668.5 POU3F1






Network of associatons between targets according to the STRING database.



First level regulatory network of POU2F2_POU3F1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_+_23847339 27.107 ENST00000303531.7
PRKCB
protein kinase C, beta
chr16_+_23847267 23.266 ENST00000321728.7
PRKCB
protein kinase C, beta
chr16_+_32077386 15.465 ENST00000354689.6
IGHV3OR16-9
immunoglobulin heavy variable 3/OR16-9 (non-functional)
chr14_-_106692191 12.212 ENST00000390607.2
IGHV3-21
immunoglobulin heavy variable 3-21
chr14_-_106573756 10.463 ENST00000390601.2
IGHV3-11
immunoglobulin heavy variable 3-11 (gene/pseudogene)
chr1_+_228645796 10.409 ENST00000369160.2
HIST3H2BB
histone cluster 3, H2bb
chr8_+_56792355 10.317 ENST00000519728.1
LYN
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr6_+_26124373 10.153 ENST00000377791.2
ENST00000602637.1
HIST1H2AC

histone cluster 1, H2ac

chr6_-_27114577 9.362 ENST00000356950.1
ENST00000396891.4
HIST1H2BK

histone cluster 1, H2bk

chr6_-_26124138 9.226 ENST00000314332.5
ENST00000396984.1
HIST1H2BC

histone cluster 1, H2bc

chr8_+_56792377 9.097 ENST00000520220.2
LYN
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr16_+_33605231 9.088 ENST00000570121.2
IGHV3OR16-12
immunoglobulin heavy variable 3/OR16-12 (non-functional)
chrX_-_48776292 8.982 ENST00000376509.4
PIM2
pim-2 oncogene
chr14_-_106994333 8.849 ENST00000390624.2
IGHV3-48
immunoglobulin heavy variable 3-48
chr6_+_26183958 8.757 ENST00000356530.3
HIST1H2BE
histone cluster 1, H2be
chr14_-_106926724 8.599 ENST00000434710.1
IGHV3-43
immunoglobulin heavy variable 3-43
chr1_-_149783914 8.588 ENST00000369167.1
ENST00000427880.2
ENST00000545683.1
HIST2H2BF


histone cluster 2, H2bf


chr14_-_106552755 7.753 ENST00000390600.2
IGHV3-9
immunoglobulin heavy variable 3-9
chr6_-_26216872 7.114 ENST00000244601.3
HIST1H2BG
histone cluster 1, H2bg
chr19_-_17516449 7.029 ENST00000252593.6
BST2
bone marrow stromal cell antigen 2
chr15_-_20193370 7.009 ENST00000558565.2
IGHV3OR15-7
immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr1_-_149814478 6.295 ENST00000369161.3
HIST2H2AA3
histone cluster 2, H2aa3
chr6_+_26273144 5.969 ENST00000377733.2
HIST1H2BI
histone cluster 1, H2bi
chr14_-_106845789 5.860 ENST00000390617.2
IGHV3-35
immunoglobulin heavy variable 3-35 (non-functional)
chr22_+_23077065 5.670 ENST00000390310.2
IGLV2-18
immunoglobulin lambda variable 2-18
chr6_+_26251835 5.421 ENST00000356350.2
HIST1H2BH
histone cluster 1, H2bh
chr14_-_106518922 5.324 ENST00000390598.2
IGHV3-7
immunoglobulin heavy variable 3-7
chr1_+_149822620 5.289 ENST00000369159.2
HIST2H2AA4
histone cluster 2, H2aa4
chr22_+_22930626 4.981 ENST00000390302.2
IGLV2-33
immunoglobulin lambda variable 2-33 (non-functional)
chr22_+_23040274 4.979 ENST00000390306.2
IGLV2-23
immunoglobulin lambda variable 2-23
chr3_+_98250743 4.749 ENST00000284311.3
GPR15
G protein-coupled receptor 15
chr18_-_53089723 4.677 ENST00000561992.1
ENST00000562512.2
TCF4

transcription factor 4

chr6_+_26217159 4.475 ENST00000303910.2
HIST1H2AE
histone cluster 1, H2ae
chr16_+_33020496 4.320 ENST00000565407.2
IGHV3OR16-8
immunoglobulin heavy variable 3/OR16-8 (non-functional)
chr6_+_26158343 4.308 ENST00000377777.4
ENST00000289316.2
HIST1H2BD

histone cluster 1, H2bd

chr1_+_149858461 4.237 ENST00000331380.2
HIST2H2AC
histone cluster 2, H2ac
chr8_+_19796381 4.100 ENST00000524029.1
ENST00000522701.1
ENST00000311322.8
LPL


lipoprotein lipase


chr17_-_47841485 4.058 ENST00000506156.1
ENST00000240364.2
FAM117A

family with sequence similarity 117, member A

chrX_+_12993202 4.012 ENST00000451311.2
ENST00000380636.1
TMSB4X

thymosin beta 4, X-linked

chr10_-_98031310 3.980 ENST00000427367.2
ENST00000413476.2
BLNK

B-cell linker

chr10_-_98031265 3.834 ENST00000224337.5
ENST00000371176.2
BLNK

B-cell linker

chr16_-_33647696 3.798 ENST00000558425.1
ENST00000569103.2
RP11-812E19.9

Uncharacterized protein

chr22_+_23165153 3.721 ENST00000390317.2
IGLV2-8
immunoglobulin lambda variable 2-8
chr4_-_71532339 3.653 ENST00000254801.4
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr6_-_27100529 3.538 ENST00000607124.1
ENST00000339812.2
ENST00000541790.1
HIST1H2BJ


histone cluster 1, H2bj


chr4_-_40517984 3.525 ENST00000381795.6
RBM47
RNA binding motif protein 47
chr16_+_33629600 3.483 ENST00000562905.2
IGHV3OR16-13
immunoglobulin heavy variable 3/OR16-13 (non-functional)
chr1_+_167298281 3.194 ENST00000367862.5
POU2F1
POU class 2 homeobox 1
chr1_-_154832316 3.145 ENST00000361147.4
KCNN3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr6_+_37137939 3.073 ENST00000373509.5
PIM1
pim-1 oncogene
chr6_+_6588902 3.069 ENST00000230568.4
LY86
lymphocyte antigen 86
chrX_+_12993336 3.007 ENST00000380635.1
TMSB4X
thymosin beta 4, X-linked
chr1_+_156119798 2.938 ENST00000355014.2
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr6_-_27860956 2.859 ENST00000359611.2
HIST1H2AM
histone cluster 1, H2am
chr2_-_89399845 2.829 ENST00000479981.1
IGKV1-16
immunoglobulin kappa variable 1-16
chr6_-_99797522 2.772 ENST00000389677.5
FAXC
failed axon connections homolog (Drosophila)
chr6_+_27100811 2.716 ENST00000359193.2
HIST1H2AG
histone cluster 1, H2ag
chr15_-_58357932 2.678 ENST00000347587.3
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr6_+_27114861 2.552 ENST00000377459.1
HIST1H2AH
histone cluster 1, H2ah
chrX_+_108779004 2.524 ENST00000218004.1
NXT2
nuclear transport factor 2-like export factor 2
chr14_-_107078851 2.491 ENST00000390628.2
IGHV1-58
immunoglobulin heavy variable 1-58
chr8_-_33370607 2.486 ENST00000360742.5
ENST00000523305.1
TTI2

TELO2 interacting protein 2

chr14_-_106586656 2.439 ENST00000390602.2
IGHV3-13
immunoglobulin heavy variable 3-13
chr12_+_113344582 2.395 ENST00000202917.5
ENST00000445409.2
ENST00000452357.2
OAS1


2'-5'-oligoadenylate synthetase 1, 40/46kDa


chr12_+_113344755 2.340 ENST00000550883.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr14_-_106539557 2.335 ENST00000390599.2
IGHV1-8
immunoglobulin heavy variable 1-8
chr16_+_33006369 2.285 ENST00000425181.3
IGHV3OR16-10
immunoglobulin heavy variable 3/OR16-10 (non-functional)
chr16_+_32063311 2.258 ENST00000426099.1
AC142381.1
AC142381.1
chr14_-_106816253 2.210 ENST00000390615.2
IGHV3-33
immunoglobulin heavy variable 3-33
chr21_+_10862622 2.155 ENST00000302092.5
ENST00000559480.1
IGHV1OR21-1

immunoglobulin heavy variable 1/OR21-1 (non-functional)

chr22_+_22550113 2.131 ENST00000390285.3
IGLV6-57
immunoglobulin lambda variable 6-57
chr14_-_107049312 2.123 ENST00000390627.2
IGHV3-53
immunoglobulin heavy variable 3-53
chr12_-_31479045 2.084 ENST00000539409.1
ENST00000395766.1
FAM60A

family with sequence similarity 60, member A

chr17_+_20059302 2.016 ENST00000395530.2
SPECC1
sperm antigen with calponin homology and coiled-coil domains 1
chr15_+_84115868 2.008 ENST00000427482.2
SH3GL3
SH3-domain GRB2-like 3
chrX_-_80457385 1.999 ENST00000451455.1
ENST00000436386.1
ENST00000358130.2
HMGN5


high mobility group nucleosome binding domain 5


chr14_-_107283278 1.974 ENST00000390639.2
IGHV7-81
immunoglobulin heavy variable 7-81 (non-functional)
chr15_-_58357866 1.925 ENST00000537372.1
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr4_-_74088800 1.851 ENST00000509867.2
ANKRD17
ankyrin repeat domain 17
chr15_-_20170354 1.793 ENST00000338912.5
IGHV1OR15-9
immunoglobulin heavy variable 1/OR15-9 (non-functional)
chr9_-_124991124 1.779 ENST00000394319.4
ENST00000340587.3
LHX6

LIM homeobox 6

chr13_-_52027134 1.773 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
INTS6




integrator complex subunit 6




chr12_+_62654119 1.758 ENST00000353364.3
ENST00000549523.1
ENST00000280377.5
USP15


ubiquitin specific peptidase 15


chr2_-_172750733 1.758 ENST00000392592.4
ENST00000422440.2
SLC25A12

solute carrier family 25 (aspartate/glutamate carrier), member 12

chr12_-_68696652 1.746 ENST00000539972.1
MDM1
Mdm1 nuclear protein homolog (mouse)
chr2_-_136678123 1.697 ENST00000422708.1
DARS
aspartyl-tRNA synthetase
chr2_-_89340242 1.689 ENST00000480492.1
IGKV1-12
immunoglobulin kappa variable 1-12
chr14_-_107114267 1.672 ENST00000454421.2
IGHV3-64
immunoglobulin heavy variable 3-64
chr14_-_107219365 1.656 ENST00000424969.2
IGHV3-74
immunoglobulin heavy variable 3-74
chr3_-_119276575 1.639 ENST00000383669.3
ENST00000383668.3
CD80

CD80 molecule

chr6_+_34204642 1.634 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
HMGA1




high mobility group AT-hook 1




chr14_-_106866934 1.621 ENST00000390618.2
IGHV3-38
immunoglobulin heavy variable 3-38 (non-functional)
chr12_+_62654155 1.605 ENST00000312635.6
ENST00000393654.3
ENST00000549237.1
USP15


ubiquitin specific peptidase 15


chr3_-_24207039 1.569 ENST00000280696.5
THRB
thyroid hormone receptor, beta
chr15_+_84116106 1.563 ENST00000535412.1
ENST00000324537.5
SH3GL3

SH3-domain GRB2-like 3

chr16_+_85645007 1.549 ENST00000405402.2
GSE1
Gse1 coiled-coil protein
chr22_+_22764088 1.544 ENST00000390299.2
IGLV1-40
immunoglobulin lambda variable 1-40
chr14_-_106725723 1.543 ENST00000390609.2
IGHV3-23
immunoglobulin heavy variable 3-23
chr6_-_27782548 1.537 ENST00000333151.3
HIST1H2AJ
histone cluster 1, H2aj
chr7_+_26438187 1.492 ENST00000439120.1
ENST00000430548.1
ENST00000421862.1
ENST00000449537.1
ENST00000420774.1
ENST00000418758.2
AC004540.5





AC004540.5





chr5_-_179045199 1.481 ENST00000523921.1
HNRNPH1
heterogeneous nuclear ribonucleoprotein H1 (H)
chr22_+_22712087 1.471 ENST00000390294.2
IGLV1-47
immunoglobulin lambda variable 1-47
chr2_+_58134756 1.453 ENST00000435505.2
ENST00000417641.2
VRK2

vaccinia related kinase 2

chr12_+_113344811 1.402 ENST00000551241.1
ENST00000553185.1
ENST00000550689.1
OAS1


2'-5'-oligoadenylate synthetase 1, 40/46kDa


chr18_-_52989525 1.320 ENST00000457482.3
TCF4
transcription factor 4
chr8_-_57123815 1.320 ENST00000316981.3
ENST00000423799.2
ENST00000429357.2
PLAG1


pleiomorphic adenoma gene 1


chr22_-_29107919 1.293 ENST00000434810.1
ENST00000456369.1
CHEK2

checkpoint kinase 2

chr2_+_90139056 1.287 ENST00000492446.1
IGKV1D-16
immunoglobulin kappa variable 1D-16
chr4_-_144940477 1.283 ENST00000513128.1
ENST00000429670.2
ENST00000502664.1
GYPB


glycophorin B (MNS blood group)


chr22_+_22735135 1.280 ENST00000390297.2
IGLV1-44
immunoglobulin lambda variable 1-44
chr6_+_27215494 1.274 ENST00000230582.3
PRSS16
protease, serine, 16 (thymus)
chr22_-_24096562 1.265 ENST00000398465.3
VPREB3
pre-B lymphocyte 3
chr19_-_41903161 1.256 ENST00000602129.1
ENST00000593771.1
ENST00000596905.1
ENST00000221233.4
EXOSC5



exosome component 5



chr6_-_27775694 1.244 ENST00000377401.2
HIST1H2BL
histone cluster 1, H2bl
chr8_-_16859690 1.235 ENST00000180166.5
FGF20
fibroblast growth factor 20
chr2_+_90198535 1.224 ENST00000390276.2
IGKV1D-12
immunoglobulin kappa variable 1D-12
chr4_-_25865159 1.220 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
SEL1L3



sel-1 suppressor of lin-12-like 3 (C. elegans)



chr15_-_66649010 1.196 ENST00000367709.4
ENST00000261881.4
TIPIN

TIMELESS interacting protein

chr2_+_90192768 1.196 ENST00000390275.2
IGKV1D-13
immunoglobulin kappa variable 1D-13
chr6_+_27215471 1.191 ENST00000421826.2
PRSS16
protease, serine, 16 (thymus)
chr1_+_32666188 1.191 ENST00000421922.2
CCDC28B
coiled-coil domain containing 28B
chr11_-_11374904 1.190 ENST00000528848.2
CSNK2A3
casein kinase 2, alpha 3 polypeptide
chr11_-_5248294 1.179 ENST00000335295.4
HBB
hemoglobin, beta
chr19_+_35820064 1.146 ENST00000341773.6
ENST00000600131.1
ENST00000270311.6
ENST00000595780.1
ENST00000597916.1
ENST00000593867.1
ENST00000600424.1
ENST00000599811.1
ENST00000536635.2
ENST00000085219.5
ENST00000544992.2
ENST00000419549.2
CD22











CD22 molecule











chr6_+_27861190 1.144 ENST00000303806.4
HIST1H2BO
histone cluster 1, H2bo
chr3_+_157827841 1.126 ENST00000295930.3
ENST00000471994.1
ENST00000464171.1
ENST00000312179.6
ENST00000475278.2
RSRC1




arginine/serine-rich coiled-coil 1




chr15_+_67841330 1.092 ENST00000354498.5
MAP2K5
mitogen-activated protein kinase kinase 5
chr14_-_107131560 1.069 ENST00000390632.2
IGHV3-66
immunoglobulin heavy variable 3-66
chr10_-_103880209 1.065 ENST00000425280.1
LDB1
LIM domain binding 1
chr6_-_89927151 1.054 ENST00000454853.2
GABRR1
gamma-aminobutyric acid (GABA) A receptor, rho 1
chr17_-_61850894 1.015 ENST00000403162.3
ENST00000582252.1
ENST00000225726.5
CCDC47


coiled-coil domain containing 47


chr6_+_27775899 1.008 ENST00000358739.3
HIST1H2AI
histone cluster 1, H2ai
chr3_-_33686743 1.000 ENST00000333778.6
ENST00000539981.1
CLASP2

cytoplasmic linker associated protein 2

chr16_+_53164833 0.992 ENST00000564845.1
CHD9
chromodomain helicase DNA binding protein 9
chr19_+_17858509 0.977 ENST00000594202.1
ENST00000252771.7
ENST00000389133.4
FCHO1


FCH domain only 1


chr12_-_56359802 0.972 ENST00000548803.1
ENST00000449260.2
ENST00000550447.1
ENST00000547137.1
ENST00000546543.1
ENST00000550464.1
PMEL





premelanosome protein





chr19_+_35861831 0.949 ENST00000454971.1
GPR42
G protein-coupled receptor 42 (gene/pseudogene)
chr6_-_43655511 0.947 ENST00000372133.3
ENST00000372116.1
ENST00000427312.1
MRPS18A


mitochondrial ribosomal protein S18A


chr7_+_50348268 0.935 ENST00000438033.1
ENST00000439701.1
IKZF1

IKAROS family zinc finger 1 (Ikaros)

chr19_-_50168962 0.934 ENST00000599223.1
ENST00000593922.1
ENST00000600022.1
ENST00000596765.1
ENST00000599144.1
ENST00000596822.1
ENST00000598108.1
ENST00000601373.1
ENST00000595034.1
ENST00000601291.1
IRF3









interferon regulatory factor 3









chr6_-_168479839 0.932 ENST00000283309.6
FRMD1
FERM domain containing 1
chr1_+_32538492 0.920 ENST00000336294.5
TMEM39B
transmembrane protein 39B
chr4_-_152682129 0.920 ENST00000512306.1
ENST00000508611.1
ENST00000515812.1
ENST00000263985.6
PET112



PET112 homolog (yeast)



chr18_-_53253112 0.912 ENST00000568673.1
ENST00000562847.1
ENST00000568147.1
TCF4


transcription factor 4


chr2_+_89901292 0.911 ENST00000448155.2
IGKV1D-39
immunoglobulin kappa variable 1D-39
chr2_+_114163945 0.908 ENST00000453673.3
IGKV1OR2-108
immunoglobulin kappa variable 1/OR2-108 (non-functional)
chr19_-_50169064 0.906 ENST00000593337.1
ENST00000598808.1
ENST00000600453.1
ENST00000593818.1
ENST00000597198.1
ENST00000601809.1
ENST00000377139.3
IRF3






interferon regulatory factor 3






chr12_-_48963829 0.896 ENST00000301046.2
ENST00000549817.1
LALBA

lactalbumin, alpha-

chr6_+_122720681 0.895 ENST00000368455.4
ENST00000452194.1
HSF2

heat shock transcription factor 2

chr9_-_124990680 0.872 ENST00000541397.2
ENST00000560485.1
LHX6

LIM homeobox 6

chr6_+_43139037 0.867 ENST00000265354.4
SRF
serum response factor (c-fos serum response element-binding transcription factor)
chr1_+_166808692 0.846 ENST00000367876.4
POGK
pogo transposable element with KRAB domain
chr22_+_22385332 0.844 ENST00000390282.2
IGLV4-69
immunoglobulin lambda variable 4-69
chr22_-_17640110 0.844 ENST00000399852.3
ENST00000336737.4
CECR5

cat eye syndrome chromosome region, candidate 5

chr1_-_190446759 0.832 ENST00000367462.3
BRINP3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr2_+_90248739 0.829 ENST00000468879.1
IGKV1D-43
immunoglobulin kappa variable 1D-43
chr15_-_83240507 0.828 ENST00000564522.1
ENST00000398592.2
CPEB1

cytoplasmic polyadenylation element binding protein 1

chr15_-_83240553 0.825 ENST00000423133.2
ENST00000398591.2
CPEB1

cytoplasmic polyadenylation element binding protein 1

chr2_+_97426631 0.819 ENST00000377075.2
CNNM4
cyclin M4
chr14_-_106622419 0.818 ENST00000390604.2
IGHV3-16
immunoglobulin heavy variable 3-16 (non-functional)
chr3_+_119316689 0.817 ENST00000273371.4
PLA1A
phospholipase A1 member A
chr10_-_51130715 0.808 ENST00000402038.3
PARG
poly (ADP-ribose) glycohydrolase
chr19_-_18508396 0.806 ENST00000595840.1
ENST00000339007.3
LRRC25

leucine rich repeat containing 25

chr22_-_24096630 0.788 ENST00000248948.3
VPREB3
pre-B lymphocyte 3
chr16_-_21314360 0.784 ENST00000219599.3
ENST00000576703.1
CRYM

crystallin, mu

chr17_+_61851504 0.771 ENST00000359353.5
ENST00000389924.2
DDX42

DEAD (Asp-Glu-Ala-Asp) box helicase 42

chr19_+_41305085 0.766 ENST00000303961.4
EGLN2
egl-9 family hypoxia-inducible factor 2
chr1_-_149858227 0.755 ENST00000369155.2
HIST2H2BE
histone cluster 2, H2be
chr18_-_52989217 0.752 ENST00000570287.2
TCF4
transcription factor 4
chr6_-_55739542 0.752 ENST00000446683.2
BMP5
bone morphogenetic protein 5
chrX_-_3761898 0.734 ENST00000425492.2
RP11-706O15.1
HCG1981372, isoform CRA_c; Uncharacterized protein
chr17_-_19651668 0.728 ENST00000494157.2
ENST00000225740.6
ALDH3A1

aldehyde dehydrogenase 3 family, member A1

chr2_+_89998789 0.722 ENST00000453166.2
IGKV2D-28
immunoglobulin kappa variable 2D-28
chr6_-_35656712 0.720 ENST00000357266.4
ENST00000542713.1
FKBP5

FK506 binding protein 5

chr6_+_97010424 0.719 ENST00000541107.1
ENST00000450218.1
ENST00000326771.2
FHL5


four and a half LIM domains 5


chr1_+_32538520 0.718 ENST00000438825.1
ENST00000456834.2
ENST00000373634.4
ENST00000427288.1
TMEM39B



transmembrane protein 39B



chr14_-_107170409 0.709 ENST00000390633.2
IGHV1-69
immunoglobulin heavy variable 1-69
chr2_-_89247338 0.702 ENST00000496168.1
IGKV1-5
immunoglobulin kappa variable 1-5
chr2_-_2334888 0.699 ENST00000428368.2
ENST00000399161.2
MYT1L

myelin transcription factor 1-like

chrX_+_129535937 0.683 ENST00000305536.6
ENST00000370947.1
RBMX2

RNA binding motif protein, X-linked 2

chr9_+_108463234 0.682 ENST00000374688.1
TMEM38B
transmembrane protein 38B
chr22_-_22221900 0.681 ENST00000215832.6
ENST00000398822.3
MAPK1

mitogen-activated protein kinase 1

chr2_-_89417335 0.680 ENST00000490686.1
IGKV1-17
immunoglobulin kappa variable 1-17
chr19_-_50168861 0.677 ENST00000596756.1
IRF3
interferon regulatory factor 3
chr6_-_35656685 0.676 ENST00000539068.1
ENST00000540787.1
FKBP5

FK506 binding protein 5

chr1_-_68962805 0.671 ENST00000370966.5
DEPDC1
DEP domain containing 1
chr7_+_18535346 0.664 ENST00000405010.3
ENST00000406451.4
ENST00000428307.2
HDAC9


histone deacetylase 9


chr3_+_119316721 0.654 ENST00000488919.1
ENST00000495992.1
PLA1A

phospholipase A1 member A

chr12_+_14518598 0.653 ENST00000261168.4
ENST00000538511.1
ENST00000545723.1
ENST00000543189.1
ENST00000536444.1
ATF7IP




activating transcription factor 7 interacting protein




chr19_-_18392422 0.647 ENST00000252818.3
JUND
jun D proto-oncogene
chr6_-_53013620 0.646 ENST00000259803.7
GCM1
glial cells missing homolog 1 (Drosophila)
chrX_+_99839799 0.642 ENST00000373031.4
TNMD
tenomodulin
chr2_-_70529180 0.640 ENST00000450256.1
ENST00000037869.3
FAM136A

family with sequence similarity 136, member A

chr2_+_89923550 0.629 ENST00000509129.1
IGKV1D-37
immunoglobulin kappa variable 1D-37 (non-functional)
chr3_-_107777208 0.629 ENST00000398258.3
CD47
CD47 molecule
chr2_-_225811747 0.616 ENST00000409592.3
DOCK10
dedicator of cytokinesis 10
chr2_-_89619904 0.615 ENST00000498574.1
IGKV1-39
immunoglobulin kappa variable 1-39 (gene/pseudogene)
chr17_-_19651654 0.614 ENST00000395555.3
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr20_+_62795827 0.612 ENST00000328439.1
ENST00000536311.1
MYT1

myelin transcription factor 1

chr19_+_35862192 0.611 ENST00000597214.1
GPR42
G protein-coupled receptor 42 (gene/pseudogene)

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
16.8 50.4 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
6.5 19.4 GO:0070445 Fc receptor mediated stimulatory signaling pathway(GO:0002431) regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369) oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445) positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
1.8 9.0 GO:0010508 positive regulation of autophagy(GO:0010508)
1.0 7.0 GO:0042989 sequestering of actin monomers(GO:0042989)
0.8 4.1 GO:0034371 positive regulation of sequestering of triglyceride(GO:0010890) chylomicron remodeling(GO:0034371)
0.8 75.8 GO:0006334 nucleosome assembly(GO:0006334)
0.6 1.7 GO:0008050 female courtship behavior(GO:0008050)
0.5 3.1 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.4 3.1 GO:0031657 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031657) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.4 4.6 GO:0006776 vitamin A metabolic process(GO:0006776)
0.4 1.6 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.4 2.7 GO:0021830 interneuron migration from the subpallium to the cortex(GO:0021830) cerebral cortex GABAergic interneuron migration(GO:0021853) cerebral cortex GABAergic interneuron development(GO:0021894) interneuron migration(GO:1904936)
0.4 1.1 GO:0046984 regulation of hemoglobin biosynthetic process(GO:0046984)
0.3 1.2 GO:0033262 regulation of nuclear cell cycle DNA replication(GO:0033262) replication fork protection(GO:0048478)
0.3 1.7 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.2 1.5 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.2 1.6 GO:0045627 regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423) positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425) positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.2 0.7 GO:0019858 cytosine metabolic process(GO:0019858)
0.2 0.9 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.2 8.3 GO:0065004 protein-DNA complex assembly(GO:0065004)
0.2 1.2 GO:0030185 nitric oxide transport(GO:0030185)
0.2 2.5 GO:0043330 response to exogenous dsRNA(GO:0043330) type I interferon biosynthetic process(GO:0045351)
0.1 0.7 GO:0007288 sperm axoneme assembly(GO:0007288)
0.1 1.3 GO:0016180 snRNA processing(GO:0016180)
0.1 0.4 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.1 0.9 GO:0005984 disaccharide metabolic process(GO:0005984)
0.1 0.5 GO:0034310 primary alcohol catabolic process(GO:0034310)
0.1 0.6 GO:0007100 mitotic centrosome separation(GO:0007100)
0.1 0.4 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.1 16.9 GO:0006959 humoral immune response(GO:0006959)
0.1 1.0 GO:0006983 ER overload response(GO:0006983)
0.1 0.4 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 0.5 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.6 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.1 0.5 GO:0045767 obsolete regulation of anti-apoptosis(GO:0045767)
0.1 1.3 GO:0060736 prostate gland growth(GO:0060736)
0.1 0.8 GO:0016045 detection of bacterium(GO:0016045)
0.1 0.4 GO:0072369 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716) regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.1 0.2 GO:0072201 negative regulation of mesenchymal cell proliferation(GO:0072201)
0.1 0.4 GO:0009642 response to light intensity(GO:0009642)
0.1 0.8 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 1.1 GO:0030539 male genitalia development(GO:0030539)
0.1 0.9 GO:0009223 pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.1 0.3 GO:0045872 regulation of rhodopsin gene expression(GO:0007468) positive regulation of rhodopsin gene expression(GO:0045872)
0.1 0.3 GO:0070933 histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.1 0.5 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.1 1.0 GO:0032438 melanosome organization(GO:0032438) pigment granule organization(GO:0048753)
0.1 6.1 GO:0071357 response to type I interferon(GO:0034340) type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.1 0.3 GO:0032736 positive regulation of interleukin-13 production(GO:0032736)
0.1 1.3 GO:0090399 replicative senescence(GO:0090399)
0.1 0.3 GO:0040016 embryonic cleavage(GO:0040016)
0.1 0.2 GO:0043276 anoikis(GO:0043276)
0.1 0.3 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.1 1.0 GO:0007020 microtubule nucleation(GO:0007020)
0.1 1.1 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.1 1.3 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1 0.3 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 1.4 GO:0018208 peptidyl-proline modification(GO:0018208)
0.0 0.1 GO:0048865 stem cell fate commitment(GO:0048865) stem cell fate determination(GO:0048867)
0.0 0.5 GO:0048488 synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0 0.6 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.2 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.2 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.6 GO:0002076 osteoblast development(GO:0002076)
0.0 0.1 GO:0045591 positive regulation of regulatory T cell differentiation(GO:0045591)
0.0 0.8 GO:0060113 inner ear receptor cell differentiation(GO:0060113)
0.0 1.1 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.2 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.7 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 1.8 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.8 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.0 0.4 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.5 GO:0030097 hemopoiesis(GO:0030097)
0.0 0.1 GO:0010842 retina layer formation(GO:0010842)
0.0 0.4 GO:0060711 labyrinthine layer development(GO:0060711)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.4 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.0 1.8 GO:0006094 gluconeogenesis(GO:0006094)
0.0 0.8 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.1 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.3 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 1.7 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 0.1 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.0 0.5 GO:0006665 sphingolipid metabolic process(GO:0006665)
0.0 1.2 GO:0051591 response to cAMP(GO:0051591)
0.0 2.5 GO:0051028 mRNA transport(GO:0051028)
0.0 0.2 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.1 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.5 GO:0035272 exocrine system development(GO:0035272)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 19.4 GO:0030061 mitochondrial crista(GO:0030061)
1.5 75.8 GO:0000786 nucleosome(GO:0000786)
0.4 1.3 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.3 1.2 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.2 1.0 GO:0032585 multivesicular body membrane(GO:0032585)
0.2 4.1 GO:0042627 chylomicron(GO:0042627)
0.2 1.8 GO:0032039 integrator complex(GO:0032039)
0.1 1.0 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 7.0 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 0.4 GO:0008537 proteasome activator complex(GO:0008537)
0.1 0.7 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 0.2 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.1 0.9 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 7.9 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.9 GO:0030530 obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0 3.2 GO:0031901 early endosome membrane(GO:0031901)
0.0 1.7 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.6 GO:0016585 obsolete chromatin remodeling complex(GO:0016585)
0.0 6.9 GO:0000785 chromatin(GO:0000785)
0.0 0.7 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 6.8 GO:0005792 obsolete microsome(GO:0005792)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 5.0 GO:0005667 transcription factor complex(GO:0005667)
0.0 1.1 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.5 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.1 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0 0.3 GO:0001533 cornified envelope(GO:0001533)
0.0 0.6 GO:0005884 actin filament(GO:0005884)
0.0 2.5 GO:0010008 endosome membrane(GO:0010008)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
16.8 50.4 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
1.9 19.5 GO:0043208 glycosphingolipid binding(GO:0043208)
1.4 4.1 GO:0017129 triglyceride binding(GO:0017129)
0.8 3.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.7 7.8 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.6 7.7 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, RNA polymerase II basal transcription factor binding(GO:0001083) transcription factor activity, TFIIB-class binding(GO:0001087) RNA polymerase II basal transcription factor binding(GO:0001091) TFIIB-class transcription factor binding(GO:0001093)
0.4 1.8 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.4 5.9 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.3 1.6 GO:0003680 AT DNA binding(GO:0003680)
0.3 1.7 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.3 0.8 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.2 0.9 GO:0070324 thyroid hormone binding(GO:0070324)
0.2 0.9 GO:0004461 lactose synthase activity(GO:0004461)
0.2 4.7 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.2 1.3 GO:0030492 hemoglobin binding(GO:0030492)
0.2 0.9 GO:0019103 pyrimidine nucleotide binding(GO:0019103)
0.2 0.5 GO:0000150 recombinase activity(GO:0000150)
0.2 0.5 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.1 1.0 GO:0008107 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.1 1.1 GO:0070700 BMP receptor binding(GO:0070700)
0.1 1.5 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 1.6 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.1 0.5 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.1 0.7 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 1.1 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.3 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1 0.8 GO:0019826 oxygen sensor activity(GO:0019826)
0.1 1.3 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.1 0.6 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 1.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 0.4 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.1 0.5 GO:0004875 complement receptor activity(GO:0004875)
0.1 4.4 GO:0003823 antigen binding(GO:0003823)
0.1 0.4 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 3.4 GO:0036459 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.1 0.4 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 0.6 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.1 0.7 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 3.1 GO:0030145 manganese ion binding(GO:0030145)
0.1 0.3 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 1.4 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.3 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 1.6 GO:0015026 coreceptor activity(GO:0015026)
0.0 3.5 GO:0016779 nucleotidyltransferase activity(GO:0016779)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.6 GO:0005522 profilin binding(GO:0005522)
0.0 0.3 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0 1.1 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.1 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.0 67.8 GO:0003677 DNA binding(GO:0003677)
0.0 0.4 GO:0005123 death receptor binding(GO:0005123)
0.0 0.4 GO:0043499 obsolete eukaryotic cell surface binding(GO:0043499)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.8 GO:0010843 obsolete promoter binding(GO:0010843)
0.0 0.4 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.2 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.5 GO:0019209 kinase activator activity(GO:0019209)
0.0 0.3 GO:0005523 tropomyosin binding(GO:0005523)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 27.9 SA_B_CELL_RECEPTOR_COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 1.1 ST_GA12_PATHWAY G alpha 12 Pathway
0.0 0.9 ST_GA13_PATHWAY G alpha 13 Pathway
0.0 0.4 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.8 SIG_BCR_SIGNALING_PATHWAY Members of the BCR signaling pathway