Motif ID: POU3F3_POU3F4

Z-value: 1.790

Transcription factors associated with POU3F3_POU3F4:

Gene SymbolEntrez IDGene Name
POU3F3 ENSG00000198914.2 POU3F3
POU3F4 ENSG00000196767.4 POU3F4






Network of associatons between targets according to the STRING database.



First level regulatory network of POU3F3_POU3F4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_189839046 4.708 ENST00000304636.3
ENST00000317840.5
COL3A1

collagen, type III, alpha 1

chr8_-_49833978 3.464 ENST00000020945.1
SNAI2
snail family zinc finger 2
chr10_-_75226166 3.396 ENST00000544628.1
PPP3CB
protein phosphatase 3, catalytic subunit, beta isozyme
chr5_+_125758813 3.194 ENST00000285689.3
ENST00000515200.1
GRAMD3

GRAM domain containing 3

chr12_-_91505608 3.154 ENST00000266718.4
LUM
lumican
chr5_+_125758865 3.142 ENST00000542322.1
ENST00000544396.1
GRAMD3

GRAM domain containing 3

chrX_+_65382433 3.025 ENST00000374727.3
HEPH
hephaestin
chr5_+_119867159 3.001 ENST00000505123.1
PRR16
proline rich 16
chr8_-_49834299 2.868 ENST00000396822.1
SNAI2
snail family zinc finger 2
chr1_-_193155729 2.792 ENST00000367434.4
B3GALT2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr6_-_46459675 2.623 ENST00000306764.7
RCAN2
regulator of calcineurin 2
chr13_+_102142296 2.103 ENST00000376162.3
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr12_-_91573249 2.072 ENST00000550099.1
ENST00000546391.1
ENST00000551354.1
DCN


decorin


chr3_+_158787041 2.040 ENST00000471575.1
ENST00000476809.1
ENST00000485419.1
IQCJ-SCHIP1


IQCJ-SCHIP1 readthrough


chr3_+_35722487 1.957 ENST00000441454.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr3_-_107777208 1.871 ENST00000398258.3
CD47
CD47 molecule
chr11_-_2906979 1.820 ENST00000380725.1
ENST00000313407.6
ENST00000430149.2
ENST00000440480.2
ENST00000414822.3
CDKN1C




cyclin-dependent kinase inhibitor 1C (p57, Kip2)




chr11_+_2405833 1.725 ENST00000527343.1
ENST00000464784.2
CD81

CD81 molecule

chr5_+_140762268 1.684 ENST00000518325.1
PCDHGA7
protocadherin gamma subfamily A, 7
chr18_-_52989217 1.672 ENST00000570287.2
TCF4
transcription factor 4
chr13_+_102104980 1.508 ENST00000545560.2
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr17_-_10452929 1.480 ENST00000532183.2
ENST00000397183.2
ENST00000420805.1
MYH2


myosin, heavy chain 2, skeletal muscle, adult


chr14_-_61116168 1.420 ENST00000247182.6
SIX1
SIX homeobox 1
chr2_-_175711133 1.418 ENST00000409597.1
ENST00000413882.1
CHN1

chimerin 1

chr18_-_52989525 1.398 ENST00000457482.3
TCF4
transcription factor 4
chr19_-_44174330 1.372 ENST00000340093.3
PLAUR
plasminogen activator, urokinase receptor
chr12_-_91573316 1.367 ENST00000393155.1
DCN
decorin
chr12_-_91574142 1.320 ENST00000547937.1
DCN
decorin
chr12_-_91573132 1.311 ENST00000550563.1
ENST00000546370.1
DCN

decorin

chr5_-_133510456 1.299 ENST00000520417.1
SKP1
S-phase kinase-associated protein 1
chr12_-_50616382 1.165 ENST00000552783.1
LIMA1
LIM domain and actin binding 1
chr1_-_1297157 1.157 ENST00000477278.2
MXRA8
matrix-remodelling associated 8
chr19_-_44174305 1.105 ENST00000601723.1
ENST00000339082.3
PLAUR

plasminogen activator, urokinase receptor

chr5_+_140753444 1.036 ENST00000517434.1
PCDHGA6
protocadherin gamma subfamily A, 6
chr3_-_127455200 0.941 ENST00000398101.3
MGLL
monoglyceride lipase
chr8_-_27695552 0.938 ENST00000522944.1
ENST00000301905.4
PBK

PDZ binding kinase

chr8_-_91095099 0.890 ENST00000265431.3
CALB1
calbindin 1, 28kDa
chr1_-_151345159 0.833 ENST00000458566.1
ENST00000447402.3
ENST00000426705.2
ENST00000435071.1
ENST00000368868.5
SELENBP1




selenium binding protein 1




chr15_+_63569785 0.810 ENST00000380343.4
ENST00000560353.1
APH1B

APH1B gamma secretase subunit

chr17_-_66951474 0.799 ENST00000269080.2
ABCA8
ATP-binding cassette, sub-family A (ABC1), member 8
chr14_+_101297740 0.786 ENST00000555928.1
MEG3
maternally expressed 3 (non-protein coding)
chr7_-_38948774 0.773 ENST00000395969.2
ENST00000414632.1
ENST00000310301.4
VPS41


vacuolar protein sorting 41 homolog (S. cerevisiae)


chr9_-_14180778 0.724 ENST00000380924.1
ENST00000543693.1
NFIB

nuclear factor I/B

chr2_+_46769798 0.720 ENST00000238738.4
RHOQ
ras homolog family member Q
chr10_-_49813090 0.719 ENST00000249601.4
ARHGAP22
Rho GTPase activating protein 22
chr17_-_3599327 0.697 ENST00000551178.1
ENST00000552276.1
ENST00000547178.1
P2RX5


purinergic receptor P2X, ligand-gated ion channel, 5


chr3_-_141747950 0.697 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr17_-_3599696 0.683 ENST00000225328.5
P2RX5
purinergic receptor P2X, ligand-gated ion channel, 5
chr5_+_141346385 0.675 ENST00000513019.1
ENST00000356143.1
RNF14

ring finger protein 14

chr7_+_116502605 0.672 ENST00000458284.2
ENST00000490693.1
CAPZA2

capping protein (actin filament) muscle Z-line, alpha 2

chr16_-_70835034 0.659 ENST00000261776.5
VAC14
Vac14 homolog (S. cerevisiae)
chr1_+_59775752 0.659 ENST00000371212.1
FGGY
FGGY carbohydrate kinase domain containing
chr15_+_63569731 0.657 ENST00000261879.5
APH1B
APH1B gamma secretase subunit
chrX_+_80457442 0.647 ENST00000373212.5
SH3BGRL
SH3 domain binding glutamic acid-rich protein like
chr6_+_26273144 0.647 ENST00000377733.2
HIST1H2BI
histone cluster 1, H2bi
chr5_+_36152091 0.621 ENST00000274254.5
SKP2
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr10_-_49812997 0.617 ENST00000417912.2
ARHGAP22
Rho GTPase activating protein 22
chr5_+_34757309 0.610 ENST00000397449.1
RAI14
retinoic acid induced 14
chr3_-_141747439 0.609 ENST00000467667.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr5_+_36608422 0.608 ENST00000381918.3
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr5_+_36152179 0.548 ENST00000508514.1
ENST00000513151.1
ENST00000546211.1
SKP2


S-phase kinase-associated protein 2, E3 ubiquitin protein ligase


chr2_+_161993465 0.516 ENST00000457476.1
TANK
TRAF family member-associated NFKB activator
chr10_-_90712520 0.513 ENST00000224784.6
ACTA2
actin, alpha 2, smooth muscle, aorta
chrX_+_47053208 0.505 ENST00000442035.1
ENST00000457753.1
ENST00000335972.6
UBA1


ubiquitin-like modifier activating enzyme 1


chr9_-_95244781 0.505 ENST00000375544.3
ENST00000375543.1
ENST00000395538.3
ENST00000450139.2
ASPN



asporin



chr5_+_36152163 0.494 ENST00000274255.6
SKP2
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chrX_+_78003204 0.490 ENST00000435339.3
ENST00000514744.1
LPAR4

lysophosphatidic acid receptor 4

chr8_-_38008783 0.482 ENST00000276449.4
STAR
steroidogenic acute regulatory protein
chr15_-_45670924 0.479 ENST00000396659.3
GATM
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr3_-_196911002 0.468 ENST00000452595.1
DLG1
discs, large homolog 1 (Drosophila)
chr5_+_159436120 0.464 ENST00000522793.1
ENST00000231238.5
TTC1

tetratricopeptide repeat domain 1

chr12_-_71148413 0.457 ENST00000440835.2
ENST00000549308.1
ENST00000550661.1
PTPRR


protein tyrosine phosphatase, receptor type, R


chr12_-_71148357 0.445 ENST00000378778.1
PTPRR
protein tyrosine phosphatase, receptor type, R
chr2_-_55237484 0.437 ENST00000394609.2
RTN4
reticulon 4
chr6_-_49712123 0.434 ENST00000263045.4
CRISP3
cysteine-rich secretory protein 3
chr3_-_141747459 0.431 ENST00000477292.1
ENST00000478006.1
ENST00000495310.1
ENST00000486111.1
TFDP2



transcription factor Dp-2 (E2F dimerization partner 2)



chr1_-_6614565 0.429 ENST00000377705.5
NOL9
nucleolar protein 9
chr12_+_64173888 0.423 ENST00000537373.1
TMEM5
transmembrane protein 5
chr8_-_120685608 0.406 ENST00000427067.2
ENPP2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr4_-_144940477 0.404 ENST00000513128.1
ENST00000429670.2
ENST00000502664.1
GYPB


glycophorin B (MNS blood group)


chr5_-_111312622 0.403 ENST00000395634.3
NREP
neuronal regeneration related protein
chr2_+_33359687 0.398 ENST00000402934.1
ENST00000404525.1
ENST00000407925.1
LTBP1


latent transforming growth factor beta binding protein 1


chr2_+_33359646 0.397 ENST00000390003.4
ENST00000418533.2
LTBP1

latent transforming growth factor beta binding protein 1

chr5_+_140710061 0.397 ENST00000517417.1
ENST00000378105.3
PCDHGA1

protocadherin gamma subfamily A, 1

chrX_-_119445306 0.374 ENST00000371369.4
ENST00000440464.1
ENST00000519908.1
TMEM255A


transmembrane protein 255A


chr2_+_161993412 0.351 ENST00000259075.2
ENST00000432002.1
TANK

TRAF family member-associated NFKB activator

chr6_-_49712147 0.340 ENST00000433368.2
ENST00000354620.4
CRISP3

cysteine-rich secretory protein 3

chr2_+_239335449 0.339 ENST00000264607.4
ASB1
ankyrin repeat and SOCS box containing 1
chr7_+_134528635 0.328 ENST00000445569.2
CALD1
caldesmon 1
chr7_+_77469439 0.325 ENST00000450574.1
ENST00000416283.2
ENST00000248550.7
PHTF2


putative homeodomain transcription factor 2


chr1_+_152627927 0.323 ENST00000444515.1
ENST00000536536.1
LINC00302

long intergenic non-protein coding RNA 302

chr19_+_39138320 0.321 ENST00000424234.2
ENST00000390009.3
ENST00000589528.1
ACTN4


actinin, alpha 4


chr17_-_38978847 0.320 ENST00000269576.5
KRT10
keratin 10
chr15_+_59279851 0.314 ENST00000348370.4
ENST00000434298.1
ENST00000559160.1
RNF111


ring finger protein 111


chr9_+_137967366 0.298 ENST00000252854.4
OLFM1
olfactomedin 1
chr20_-_7921090 0.286 ENST00000378789.3
HAO1
hydroxyacid oxidase (glycolate oxidase) 1
chr7_+_116502527 0.284 ENST00000361183.3
CAPZA2
capping protein (actin filament) muscle Z-line, alpha 2
chr17_-_26220366 0.279 ENST00000460380.2
ENST00000508862.1
ENST00000379102.3
ENST00000582441.1
LYRM9


RP1-66C13.4
LYR motif containing 9


Uncharacterized protein
chr1_-_179112189 0.271 ENST00000512653.1
ENST00000344730.3
ABL2

c-abl oncogene 2, non-receptor tyrosine kinase

chr2_-_183387430 0.269 ENST00000410103.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr19_-_44123734 0.269 ENST00000598676.1
ZNF428
zinc finger protein 428
chr14_-_80697396 0.268 ENST00000557010.1
DIO2
deiodinase, iodothyronine, type II
chr17_+_34171081 0.267 ENST00000585577.1
TAF15
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
chr4_-_70826725 0.267 ENST00000353151.3
CSN2
casein beta
chr14_+_90722839 0.265 ENST00000261303.8
ENST00000553835.1
PSMC1

proteasome (prosome, macropain) 26S subunit, ATPase, 1

chr21_-_27423339 0.263 ENST00000415997.1
APP
amyloid beta (A4) precursor protein
chr7_+_150065278 0.252 ENST00000519397.1
ENST00000479668.1
ENST00000540729.1
REPIN1


replication initiator 1


chr14_+_90722886 0.249 ENST00000543772.2
PSMC1
proteasome (prosome, macropain) 26S subunit, ATPase, 1
chr15_+_64680003 0.244 ENST00000261884.3
TRIP4
thyroid hormone receptor interactor 4
chr12_+_59989918 0.243 ENST00000547379.1
ENST00000549465.1
SLC16A7

solute carrier family 16 (monocarboxylate transporter), member 7

chr15_+_66797627 0.243 ENST00000565627.1
ENST00000564179.1
ZWILCH

zwilch kinetochore protein

chr4_-_144826682 0.242 ENST00000358615.4
ENST00000437468.2
GYPE

glycophorin E (MNS blood group)

chrX_-_124097620 0.241 ENST00000371130.3
ENST00000422452.2
TENM1

teneurin transmembrane protein 1

chr1_+_104159999 0.241 ENST00000414303.2
ENST00000423678.1
AMY2A

amylase, alpha 2A (pancreatic)

chr2_+_89999259 0.238 ENST00000558026.1
IGKV2D-28
immunoglobulin kappa variable 2D-28
chr19_-_44124019 0.235 ENST00000300811.3
ZNF428
zinc finger protein 428
chr3_-_168865522 0.235 ENST00000464456.1
MECOM
MDS1 and EVI1 complex locus
chr3_+_111805182 0.234 ENST00000430855.1
ENST00000431717.2
ENST00000264848.5
C3orf52


chromosome 3 open reading frame 52


chr6_-_131321863 0.233 ENST00000528282.1
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr13_-_26795840 0.229 ENST00000381570.3
ENST00000399762.2
ENST00000346166.3
RNF6


ring finger protein (C3H2C3 type) 6


chr8_-_93029865 0.229 ENST00000422361.2
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr22_-_39268308 0.228 ENST00000407418.3
CBX6
chromobox homolog 6
chr8_-_41166953 0.226 ENST00000220772.3
SFRP1
secreted frizzled-related protein 1
chr5_+_141488070 0.222 ENST00000253814.4
NDFIP1
Nedd4 family interacting protein 1
chr1_-_100231349 0.220 ENST00000287474.5
ENST00000414213.1
FRRS1

ferric-chelate reductase 1

chr8_+_31496809 0.218 ENST00000518104.1
ENST00000519301.1
NRG1

neuregulin 1

chr3_+_12525931 0.214 ENST00000446004.1
ENST00000314571.7
ENST00000454502.2
ENST00000383797.5
ENST00000402228.3
ENST00000284995.6
ENST00000444864.1
TSEN2






TSEN2 tRNA splicing endonuclease subunit






chr15_+_49447947 0.213 ENST00000327171.3
ENST00000560654.1
GALK2

galactokinase 2

chr11_-_95657231 0.202 ENST00000409459.1
ENST00000352297.7
ENST00000393223.3
ENST00000346299.5
MTMR2



myotubularin related protein 2



chr5_+_140529630 0.202 ENST00000543635.1
PCDHB6
protocadherin beta 6
chrX_+_23682379 0.199 ENST00000379349.1
PRDX4
peroxiredoxin 4
chr5_+_101569696 0.196 ENST00000597120.1
AC008948.1
AC008948.1
chr4_-_168155730 0.194 ENST00000502330.1
ENST00000357154.3
SPOCK3

sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3

chr1_-_62190793 0.192 ENST00000371177.2
ENST00000606498.1
TM2D1

TM2 domain containing 1

chr1_+_101702417 0.192 ENST00000305352.6
S1PR1
sphingosine-1-phosphate receptor 1
chr1_-_179112173 0.183 ENST00000408940.3
ENST00000504405.1
ABL2

c-abl oncogene 2, non-receptor tyrosine kinase

chr11_+_33279850 0.175 ENST00000531504.1
ENST00000456517.1
HIPK3

homeodomain interacting protein kinase 3

chr15_-_30113676 0.174 ENST00000400011.2
TJP1
tight junction protein 1
chr4_+_88754113 0.174 ENST00000560249.1
ENST00000540395.1
ENST00000511670.1
ENST00000361056.3
MEPE



matrix extracellular phosphoglycoprotein



chr8_-_17942432 0.170 ENST00000381733.4
ENST00000314146.10
ASAH1

N-acylsphingosine amidohydrolase (acid ceramidase) 1

chr7_+_80267973 0.170 ENST00000394788.3
ENST00000447544.2
CD36

CD36 molecule (thrombospondin receptor)

chrX_+_134975858 0.164 ENST00000537770.1
SAGE1
sarcoma antigen 1
chr12_+_60058458 0.162 ENST00000548610.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chr2_-_101034070 0.162 ENST00000264249.3
CHST10
carbohydrate sulfotransferase 10
chr3_+_121902511 0.159 ENST00000490131.1
CASR
calcium-sensing receptor
chr11_+_17316870 0.158 ENST00000458064.2
NUCB2
nucleobindin 2
chr6_-_52859046 0.158 ENST00000457564.1
ENST00000541324.1
ENST00000370960.1
GSTA4


glutathione S-transferase alpha 4


chr2_+_185463093 0.157 ENST00000302277.6
ZNF804A
zinc finger protein 804A
chr4_+_186990298 0.156 ENST00000296795.3
ENST00000513189.1
TLR3

toll-like receptor 3

chrX_+_134975753 0.156 ENST00000535938.1
SAGE1
sarcoma antigen 1
chrX_+_54834004 0.156 ENST00000375068.1
MAGED2
melanoma antigen family D, 2
chrX_-_112084043 0.155 ENST00000304758.1
AMOT
angiomotin
chr1_-_48866517 0.155 ENST00000371841.1
SPATA6
spermatogenesis associated 6
chr15_-_90892669 0.143 ENST00000412799.2
GABARAPL3
GABA(A) receptors associated protein like 3, pseudogene
chr8_+_31497271 0.141 ENST00000520407.1
NRG1
neuregulin 1
chr14_+_70918874 0.139 ENST00000603540.1
ADAM21
ADAM metallopeptidase domain 21
chrX_-_80457385 0.132 ENST00000451455.1
ENST00000436386.1
ENST00000358130.2
HMGN5


high mobility group nucleosome binding domain 5


chr12_+_110011571 0.129 ENST00000539696.1
ENST00000228510.3
ENST00000392727.3
MVK


mevalonate kinase


chr12_-_111926342 0.128 ENST00000389154.3
ATXN2
ataxin 2
chr14_-_25479811 0.128 ENST00000550887.1
STXBP6
syntaxin binding protein 6 (amisyn)
chr1_-_109935819 0.126 ENST00000538502.1
SORT1
sortilin 1
chr12_+_27175476 0.125 ENST00000546323.1
ENST00000282892.3
MED21

mediator complex subunit 21

chr10_+_35484793 0.121 ENST00000488741.1
ENST00000474931.1
ENST00000468236.1
ENST00000344351.5
ENST00000490511.1
CREM




cAMP responsive element modulator




chr22_-_43036607 0.118 ENST00000505920.1
ATP5L2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G2
chr1_+_24019099 0.115 ENST00000443624.1
ENST00000458455.1
RPL11

ribosomal protein L11

chr1_+_212606219 0.114 ENST00000366988.3
NENF
neudesin neurotrophic factor
chr12_-_10324716 0.113 ENST00000545927.1
ENST00000432556.2
ENST00000309539.3
ENST00000544577.1
OLR1



oxidized low density lipoprotein (lectin-like) receptor 1



chr17_-_39023462 0.112 ENST00000251643.4
KRT12
keratin 12
chr12_-_102224457 0.107 ENST00000549165.1
ENST00000549940.1
ENST00000392919.4
GNPTAB


N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits


chr19_+_39138271 0.105 ENST00000252699.2
ACTN4
actinin, alpha 4
chr15_-_74658493 0.102 ENST00000419019.2
ENST00000569662.1
CYP11A1

cytochrome P450, family 11, subfamily A, polypeptide 1

chr12_-_7656357 0.102 ENST00000396620.3
ENST00000432237.2
ENST00000359156.4
CD163


CD163 molecule


chr9_+_77230499 0.098 ENST00000396204.2
RORB
RAR-related orphan receptor B
chr3_-_52931557 0.098 ENST00000355083.5
ENST00000504329.1
TMEM110
TMEM110-MUSTN1
transmembrane protein 110
TMEM110-MUSTN1 readthrough
chr5_+_140782351 0.096 ENST00000573521.1
PCDHGA9
protocadherin gamma subfamily A, 9
chrX_+_65382381 0.095 ENST00000519389.1
HEPH
hephaestin
chr2_-_183387283 0.093 ENST00000435564.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr13_-_46716969 0.092 ENST00000435666.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr3_+_130569429 0.087 ENST00000505330.1
ENST00000504381.1
ENST00000507488.2
ENST00000393221.4
ATP2C1



ATPase, Ca++ transporting, type 2C, member 1



chr1_+_104293028 0.083 ENST00000370079.3
AMY1C
amylase, alpha 1C (salivary)
chr4_+_70796784 0.081 ENST00000246891.4
ENST00000444405.3
CSN1S1

casein alpha s1

chr17_+_45608430 0.080 ENST00000322157.4
NPEPPS
aminopeptidase puromycin sensitive
chr2_+_201170703 0.079 ENST00000358677.5
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr9_+_137967268 0.075 ENST00000371799.4
ENST00000277415.11
OLFM1

olfactomedin 1

chr4_+_175839551 0.073 ENST00000404450.4
ENST00000514159.1
ADAM29

ADAM metallopeptidase domain 29

chr11_-_62369291 0.072 ENST00000278823.2
MTA2
metastasis associated 1 family, member 2
chr7_+_106505912 0.068 ENST00000359195.3
PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
chr6_+_29429217 0.067 ENST00000396792.2
OR2H1
olfactory receptor, family 2, subfamily H, member 1
chr15_+_74422585 0.066 ENST00000561740.1
ENST00000435464.1
ENST00000453268.2
ISLR2


immunoglobulin superfamily containing leucine-rich repeat 2


chr11_-_28129656 0.066 ENST00000263181.6
KIF18A
kinesin family member 18A
chr22_+_40322623 0.065 ENST00000399090.2
GRAP2
GRB2-related adaptor protein 2
chr6_-_32374900 0.064 ENST00000374995.3
ENST00000374993.1
ENST00000414363.1
ENST00000540315.1
ENST00000544175.1
ENST00000429232.2
ENST00000454136.3
ENST00000446536.2
BTNL2







butyrophilin-like 2 (MHC class II associated)







chr22_+_40322595 0.063 ENST00000420971.1
ENST00000544756.1
GRAP2

GRB2-related adaptor protein 2

chr17_-_61996136 0.062 ENST00000342364.4
GH1
growth hormone 1
chr15_+_71228826 0.062 ENST00000558456.1
ENST00000560158.2
ENST00000558808.1
ENST00000559806.1
ENST00000559069.1
LRRC49




leucine rich repeat containing 49




chr5_-_160973649 0.062 ENST00000393959.1
ENST00000517547.1
GABRB2

gamma-aminobutyric acid (GABA) A receptor, beta 2

chr8_-_59412717 0.059 ENST00000301645.3
CYP7A1
cytochrome P450, family 7, subfamily A, polypeptide 1
chr9_+_34458771 0.058 ENST00000437363.1
ENST00000242317.4
DNAI1

dynein, axonemal, intermediate chain 1

chr3_-_151047327 0.057 ENST00000325602.5
P2RY13
purinergic receptor P2Y, G-protein coupled, 13
chr2_-_220264703 0.057 ENST00000519905.1
ENST00000523282.1
ENST00000434339.1
ENST00000457935.1
DNPEP



aspartyl aminopeptidase




Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 5.6 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.6 6.1 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.5 1.4 GO:0051451 myoblast migration(GO:0051451)
0.5 4.7 GO:0097435 extracellular fibril organization(GO:0043206) fibril organization(GO:0097435)
0.4 1.7 GO:0043128 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.4 2.5 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.3 1.7 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.2 0.2 GO:0014029 neural crest formation(GO:0014029) neural crest cell fate commitment(GO:0014034)
0.2 0.8 GO:0034337 RNA folding(GO:0034337) DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029) regulation of DNA methylation(GO:0044030)
0.2 2.8 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.2 0.9 GO:2000124 cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926) regulation of endocannabinoid signaling pathway(GO:2000124)
0.2 0.6 GO:0031223 auditory behavior(GO:0031223) malate-aspartate shuttle(GO:0043490)
0.1 0.9 GO:0072205 collecting duct development(GO:0072044) metanephric tubule development(GO:0072170) metanephric collecting duct development(GO:0072205) metanephric epithelium development(GO:0072207) metanephric nephron tubule development(GO:0072234) metanephric nephron epithelium development(GO:0072243)
0.1 3.1 GO:0006825 copper ion transport(GO:0006825)
0.1 0.4 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.1 0.7 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.1 3.2 GO:0030199 collagen fibril organization(GO:0030199)
0.1 1.4 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.1 0.7 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005) negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.1 2.0 GO:0034605 cellular response to heat(GO:0034605)
0.1 0.3 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.1 0.8 GO:0071692 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1 1.5 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.1 1.8 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.1 0.3 GO:0006848 pyruvate transport(GO:0006848)
0.1 0.2 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.1 0.2 GO:0002890 negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.1 0.4 GO:2000172 regulation of branching morphogenesis of a nerve(GO:2000172)
0.1 1.3 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1 0.3 GO:0051563 smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563)
0.1 5.5 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.1 0.2 GO:0001780 neutrophil homeostasis(GO:0001780)
0.1 1.2 GO:0031529 ruffle organization(GO:0031529)
0.1 0.2 GO:0000394 RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394) tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.4 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.3 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.5 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.4 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.0 0.3 GO:0046487 glyoxylate metabolic process(GO:0046487)
0.0 0.4 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.0 0.4 GO:0010658 striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0 0.2 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0 0.7 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.0 0.2 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.6 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.0 0.2 GO:0043116 negative regulation of vascular permeability(GO:0043116)
0.0 2.5 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.2 GO:0060100 regulation of phagocytosis, engulfment(GO:0060099) positive regulation of phagocytosis, engulfment(GO:0060100) regulation of membrane invagination(GO:1905153) positive regulation of membrane invagination(GO:1905155)
0.0 0.2 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 1.0 GO:0051693 actin filament capping(GO:0051693)
0.0 0.1 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509) plasma membrane to endosome transport(GO:0048227) negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 2.9 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 3.3 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.7 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.1 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.1 GO:0070857 regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.0 0.2 GO:0007635 chemosensory behavior(GO:0007635)
0.0 0.1 GO:0002092 positive regulation of receptor internalization(GO:0002092)
0.0 0.0 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162) pyrimidine deoxyribonucleoside monophosphate metabolic process(GO:0009176) dUMP metabolic process(GO:0046078)
0.0 0.5 GO:0051353 positive regulation of oxidoreductase activity(GO:0051353)
0.0 0.0 GO:0002887 negative regulation of myeloid leukocyte mediated immunity(GO:0002887) negative regulation of leukocyte degranulation(GO:0043301)
0.0 1.2 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275) actin-mediated cell contraction(GO:0070252)
0.0 0.1 GO:0032472 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) Golgi calcium ion transport(GO:0032472) manganese ion homeostasis(GO:0055071)
0.0 0.3 GO:0042036 negative regulation of cytokine biosynthetic process(GO:0042036)
0.0 0.2 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.1 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 7.9 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.4 6.1 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 3.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 3.6 GO:0098636 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.1 1.5 GO:0032982 myosin filament(GO:0032982)
0.1 0.8 GO:0030897 HOPS complex(GO:0030897)
0.1 1.0 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 0.2 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.8 GO:0042581 specific granule(GO:0042581)
0.0 0.3 GO:0051233 spindle midzone(GO:0051233)
0.0 0.4 GO:0031143 pseudopodium(GO:0031143)
0.0 0.6 GO:0043205 fibril(GO:0043205)
0.0 2.9 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.5 GO:0001772 immunological synapse(GO:0001772)
0.0 1.3 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.3 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.1 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.8 GO:0005884 actin filament(GO:0005884)
0.0 0.2 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 1.0 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.2 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.2 GO:0008091 spectrin(GO:0008091)
0.0 0.1 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.1 GO:0045179 apical cortex(GO:0045179)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.4 4.7 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.3 2.8 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.2 3.1 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, RNA polymerase II basal transcription factor binding(GO:0001083) transcription factor activity, TFIIB-class binding(GO:0001087) RNA polymerase II basal transcription factor binding(GO:0001091) TFIIB-class transcription factor binding(GO:0001093)
0.2 2.0 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.2 2.6 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.2 9.2 GO:0005518 collagen binding(GO:0005518)
0.1 0.9 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.4 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.1 1.4 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 1.8 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 0.4 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.1 0.3 GO:0050833 pyruvate secondary active transmembrane transporter activity(GO:0005477) pyruvate transmembrane transporter activity(GO:0050833)
0.1 0.9 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.2 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.1 0.2 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.1 1.5 GO:0000146 microfilament motor activity(GO:0000146)
0.1 1.1 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.6 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314) glutamate binding(GO:0016595)
0.1 0.2 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.8 GO:0016566 obsolete specific transcriptional repressor activity(GO:0016566)
0.0 3.1 GO:0005507 copper ion binding(GO:0005507)
0.0 0.3 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.3 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.1 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386)
0.0 0.2 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.4 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.5 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 0.6 GO:0005522 profilin binding(GO:0005522)
0.0 0.2 GO:0031404 chloride ion binding(GO:0031404)
0.0 0.5 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.9 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.2 GO:0042731 PH domain binding(GO:0042731)
0.0 0.2 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.6 GO:0008430 selenium binding(GO:0008430)
0.0 0.3 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.8 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 0.3 GO:0010181 FMN binding(GO:0010181)
0.0 0.1 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.1 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.0 0.9 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.2 GO:0046625 sphingolipid binding(GO:0046625)
0.0 0.5 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 1.6 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.1 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.2 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.5 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.0 0.2 GO:0004437 obsolete inositol or phosphatidylinositol phosphatase activity(GO:0004437)
0.0 0.0 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.1 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.3 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.5 GO:0030145 manganese ion binding(GO:0030145)
0.0 2.7 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.1 SIG_BCR_SIGNALING_PATHWAY Members of the BCR signaling pathway
0.0 1.5 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.2 ST_PAC1_RECEPTOR_PATHWAY PAC1 Receptor Pathway