Motif ID: POU4F2

Z-value: 0.692


Transcription factors associated with POU4F2:

Gene SymbolEntrez IDGene Name
POU4F2 ENSG00000151615.3 POU4F2



Activity profile for motif POU4F2.

activity profile for motif POU4F2


Sorted Z-values histogram for motif POU4F2

Sorted Z-values for motif POU4F2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU4F2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_-_49834299 1.699 ENST00000396822.1
 SNAI2
snail family zinc finger 2
chr8_-_18541603 1.606 ENST00000428502.2
 PSD3
pleckstrin and Sec7 domain containing 3
chr12_-_89746173 1.579 ENST00000308385.6
 DUSP6
dual specificity phosphatase 6
chr8_-_49833978 1.567 ENST00000020945.1
 SNAI2
snail family zinc finger 2
chr4_+_169418195 1.535 ENST00000261509.6
ENST00000335742.7
 PALLD

palladin, cytoskeletal associated protein

chr3_-_79816965 1.500 ENST00000464233.1
 ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr4_+_169418255 1.113 ENST00000505667.1
ENST00000511948.1
 PALLD

palladin, cytoskeletal associated protein

chr7_-_81399329 0.905 ENST00000453411.1
ENST00000444829.2
 HGF

hepatocyte growth factor (hepapoietin A; scatter factor)

chr7_-_81399438 0.589 ENST00000222390.5
 HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr9_+_125132803 0.469 ENST00000540753.1
 PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr14_-_70883708 0.466 ENST00000256366.4
 SYNJ2BP
synaptojanin 2 binding protein
chr3_+_159557637 0.463 ENST00000445224.2
 SCHIP1
schwannomin interacting protein 1
chr1_+_40506392 0.434 ENST00000414893.1
ENST00000414281.1
ENST00000420216.1
ENST00000372792.2
ENST00000372798.1
ENST00000340450.3
ENST00000372805.3
ENST00000435719.1
ENST00000427843.1
ENST00000417287.1
ENST00000424977.1
ENST00000446031.1
 CAP1











CAP, adenylate cyclase-associated protein 1 (yeast)











chr7_-_81399411 0.424 ENST00000423064.2
 HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr17_-_64225508 0.415 ENST00000205948.6
 APOH
apolipoprotein H (beta-2-glycoprotein I)
chr9_+_125133315 0.351 ENST00000223423.4
ENST00000362012.2
 PTGS1

prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)

chr7_-_81399355 0.324 ENST00000457544.2
 HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr6_-_109777128 0.310 ENST00000358807.3
ENST00000358577.3
 MICAL1

microtubule associated monooxygenase, calponin and LIM domain containing 1

chr5_-_134914673 0.275 ENST00000512158.1
 CXCL14
chemokine (C-X-C motif) ligand 14
chr13_-_36050819 0.267 ENST00000379919.4
 MAB21L1
mab-21-like 1 (C. elegans)
chr12_-_30887948 0.228 ENST00000433722.2
 CAPRIN2
caprin family member 2
chr4_-_10686475 0.220 ENST00000226951.6
 CLNK
cytokine-dependent hematopoietic cell linker
chr18_-_71959159 0.201 ENST00000494131.2
ENST00000397914.4
ENST00000340533.4
 CYB5A


cytochrome b5 type A (microsomal)


chr6_+_39760129 0.177 ENST00000274867.4
 DAAM2
dishevelled associated activator of morphogenesis 2
chr12_+_109577202 0.150 ENST00000377848.3
ENST00000377854.5
 ACACB

acetyl-CoA carboxylase beta

chr18_+_28898052 0.146 ENST00000257192.4
 DSG1
desmoglein 1
chr17_-_7832753 0.138 ENST00000303790.2
 KCNAB3
potassium voltage-gated channel, shaker-related subfamily, beta member 3
chr14_+_32030582 0.135 ENST00000550649.1
ENST00000281081.7
 NUBPL

nucleotide binding protein-like

chr20_+_56136136 0.121 ENST00000319441.4
ENST00000543666.1
 PCK1

phosphoenolpyruvate carboxykinase 1 (soluble)

chr12_-_118797475 0.116 ENST00000541786.1
ENST00000419821.2
ENST00000541878.1
 TAOK3


TAO kinase 3


chr19_+_1269324 0.114 ENST00000589710.1
ENST00000588230.1
ENST00000413636.2
ENST00000586472.1
ENST00000589686.1
ENST00000444172.2
ENST00000587323.1
ENST00000320936.5
ENST00000587896.1
ENST00000589235.1
ENST00000591659.1
 CIRBP










cold inducible RNA binding protein










chrX_-_18690210 0.110 ENST00000379984.3
 RS1
retinoschisin 1
chr4_+_169013666 0.109 ENST00000359299.3
 ANXA10
annexin A10
chr1_+_229440129 0.094 ENST00000366688.3
 SPHAR
S-phase response (cyclin related)
chr5_-_140998481 0.093 ENST00000518047.1
 DIAPH1
diaphanous-related formin 1
chr1_-_44482979 0.084 ENST00000360584.2
ENST00000357730.2
ENST00000528803.1
 SLC6A9


solute carrier family 6 (neurotransmitter transporter, glycine), member 9


chr8_+_22857048 0.082 ENST00000251822.6
 RHOBTB2
Rho-related BTB domain containing 2
chr5_+_66300446 0.075 ENST00000261569.7
 MAST4
microtubule associated serine/threonine kinase family member 4
chr12_-_118796910 0.060 ENST00000541186.1
ENST00000539872.1
 TAOK3

TAO kinase 3

chr11_-_125550764 0.049 ENST00000527795.1
 ACRV1
acrosomal vesicle protein 1
chr6_-_111136513 0.048 ENST00000368911.3
 CDK19
cyclin-dependent kinase 19
chr11_+_118175132 0.045 ENST00000361763.4
 CD3E
CD3e molecule, epsilon (CD3-TCR complex)
chr12_+_53848505 0.033 ENST00000552819.1
ENST00000455667.3
 PCBP2

poly(rC) binding protein 2

chr14_+_55221541 0.033 ENST00000555192.1
 SAMD4A
sterile alpha motif domain containing 4A
chr2_+_44502597 0.030 ENST00000260649.6
ENST00000409387.1
 SLC3A1

solute carrier family 3 (amino acid transporter heavy chain), member 1

chr2_-_70780572 0.014 ENST00000450929.1
 TGFA
transforming growth factor, alpha
chr12_+_56510368 0.006 ENST00000546591.1
ENST00000501597.3
 RPL41

ribosomal protein L41

chrX_+_68835911 0.001 ENST00000525810.1
ENST00000527388.1
ENST00000374553.2
ENST00000374552.4
ENST00000338901.3
ENST00000524573.1
 EDA





ectodysplasin A






Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.3 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.5 1.6 GO:0035987 endodermal cell fate commitment(GO:0001711) endodermal cell differentiation(GO:0035987)
0.5 1.5 GO:0021836 chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) regulation of negative chemotaxis(GO:0050923)
0.3 2.2 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.2 0.8 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 1.6 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.1 0.4 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0 0.2 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 0.1 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.1 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.4 GO:0007190 activation of adenylate cyclase activity(GO:0007190)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.6 GO:0005884 actin filament(GO:0005884)
0.0 1.7 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.4 GO:0042627 chylomicron(GO:0042627)
0.0 0.4 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 1.6 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.6 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.2 1.5 GO:0008046 axon guidance receptor activity(GO:0008046)
0.2 0.8 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 1.6 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.4 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 1.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.0 0.2 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.1 GO:0015187 glycine transmembrane transporter activity(GO:0015187) glycine:sodium symporter activity(GO:0015375)
0.0 0.1 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.1 GO:0015643 toxic substance binding(GO:0015643)
0.0 2.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.0 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.2 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.6 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway