Motif ID: POU6F1

Z-value: 0.753


Transcription factors associated with POU6F1:

Gene SymbolEntrez IDGene Name
POU6F1 ENSG00000184271.11 POU6F1



Activity profile for motif POU6F1.

activity profile for motif POU6F1


Sorted Z-values histogram for motif POU6F1

Sorted Z-values for motif POU6F1



Network of associatons between targets according to the STRING database.



First level regulatory network of POU6F1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_91546926 1.798 ENST00000550758.1
 DCN
decorin
chr6_+_151646800 1.606 ENST00000354675.6
 AKAP12
A kinase (PRKA) anchor protein 12
chr3_-_127541194 1.450 ENST00000453507.2
 MGLL
monoglyceride lipase
chr2_-_217560248 0.992 ENST00000233813.4
 IGFBP5
insulin-like growth factor binding protein 5
chr2_+_102721023 0.949 ENST00000409589.1
ENST00000409329.1
 IL1R1

interleukin 1 receptor, type I

chr18_+_61554932 0.814 ENST00000299502.4
ENST00000457692.1
ENST00000413956.1
 SERPINB2


serpin peptidase inhibitor, clade B (ovalbumin), member 2


chr7_-_83824169 0.757 ENST00000265362.4
 SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr7_+_80267973 0.479 ENST00000394788.3
ENST00000447544.2
 CD36

CD36 molecule (thrombospondin receptor)

chr9_-_13165457 0.363 ENST00000542239.1
ENST00000538841.1
ENST00000433359.2
 MPDZ


multiple PDZ domain protein


chr14_-_70883708 0.355 ENST00000256366.4
 SYNJ2BP
synaptojanin 2 binding protein
chr3_-_114343768 0.294 ENST00000393785.2
 ZBTB20
zinc finger and BTB domain containing 20
chr9_+_128509624 0.291 ENST00000342287.5
ENST00000373487.4
 PBX3

pre-B-cell leukemia homeobox 3

chr11_-_89224139 0.246 ENST00000413594.2
 NOX4
NADPH oxidase 4
chr13_+_58206655 0.238 ENST00000377918.3
 PCDH17
protocadherin 17
chr19_+_52076425 0.236 ENST00000436511.2
 ZNF175
zinc finger protein 175
chr6_-_111804905 0.221 ENST00000358835.3
ENST00000435970.1
 REV3L

REV3-like, polymerase (DNA directed), zeta, catalytic subunit

chr5_+_115177178 0.215 ENST00000316788.7
 AP3S1
adaptor-related protein complex 3, sigma 1 subunit
chr19_-_58662139 0.211 ENST00000598312.1
 ZNF329
zinc finger protein 329
chr11_-_89223883 0.196 ENST00000528341.1
 NOX4
NADPH oxidase 4
chr20_-_58515344 0.195 ENST00000370996.3
 PPP1R3D
protein phosphatase 1, regulatory subunit 3D
chr15_-_85259330 0.191 ENST00000560266.1
 SEC11A
SEC11 homolog A (S. cerevisiae)
chr15_-_85259294 0.178 ENST00000558217.1
ENST00000558196.1
ENST00000558134.1
 SEC11A


SEC11 homolog A (S. cerevisiae)


chr15_-_85259384 0.153 ENST00000455959.3
 SEC11A
SEC11 homolog A (S. cerevisiae)
chr15_+_59279851 0.130 ENST00000348370.4
ENST00000434298.1
ENST00000559160.1
 RNF111


ring finger protein 111


chr6_-_110501200 0.125 ENST00000392586.1
ENST00000419252.1
ENST00000392589.1
ENST00000392588.1
ENST00000359451.2
 WASF1




WAS protein family, member 1




chr15_-_85259360 0.105 ENST00000559729.1
 SEC11A
SEC11 homolog A (S. cerevisiae)
chr18_+_9475001 0.104 ENST00000019317.4
 RALBP1
ralA binding protein 1
chr2_+_242289502 0.104 ENST00000451310.1
 SEPT2
septin 2
chr20_+_34129770 0.097 ENST00000348547.2
ENST00000357394.4
ENST00000447986.1
ENST00000279052.6
ENST00000416206.1
ENST00000411577.1
ENST00000413587.1
 ERGIC3






ERGIC and golgi 3






chr15_+_80351977 0.095 ENST00000559157.1
ENST00000561012.1
ENST00000564367.1
ENST00000558494.1
 ZFAND6



zinc finger, AN1-type domain 6



chr5_+_162864575 0.086 ENST00000512163.1
ENST00000393929.1
ENST00000340828.2
ENST00000511683.2
ENST00000510097.1
ENST00000511490.2
ENST00000510664.1
 CCNG1






cyclin G1






chr2_+_128403720 0.082 ENST00000272644.3
 GPR17
G protein-coupled receptor 17
chr4_+_113970772 0.075 ENST00000504454.1
ENST00000394537.3
ENST00000357077.4
ENST00000264366.6
 ANK2



ankyrin 2, neuronal



chrX_+_119737806 0.073 ENST00000371317.5
 MCTS1
malignant T cell amplified sequence 1
chr15_+_80351910 0.066 ENST00000261749.6
ENST00000561060.1
 ZFAND6

zinc finger, AN1-type domain 6

chr2_+_128403439 0.051 ENST00000544369.1
 GPR17
G protein-coupled receptor 17
chr6_+_25754927 0.049 ENST00000377905.4
ENST00000439485.2
 SLC17A4

solute carrier family 17, member 4

chr6_+_42123141 0.049 ENST00000418175.1
ENST00000541991.1
ENST00000053469.4
ENST00000394237.1
ENST00000372963.1
 GUCA1A



RP1-139D8.6
guanylate cyclase activator 1A (retina)



RP1-139D8.6
chr6_+_110501621 0.046 ENST00000368930.1
ENST00000307731.1
 CDC40

cell division cycle 40

chr22_-_32767017 0.043 ENST00000400234.1
 RFPL3S
RFPL3 antisense
chr11_+_85339623 0.039 ENST00000358867.6
ENST00000534341.1
ENST00000393375.1
ENST00000531274.1
 TMEM126B



transmembrane protein 126B



chr9_-_86955598 0.033 ENST00000376238.4
 SLC28A3
solute carrier family 28 (concentrative nucleoside transporter), member 3
chr11_+_2323349 0.029 ENST00000381121.3
 TSPAN32
tetraspanin 32
chr7_-_38407770 0.028 ENST00000390348.2
 TRGV1
T cell receptor gamma variable 1 (non-functional)
chr1_-_21377383 0.025 ENST00000374935.3
 EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr3_-_108248169 0.022 ENST00000273353.3
 MYH15
myosin, heavy chain 15
chr6_+_110501344 0.022 ENST00000368932.1
 CDC40
cell division cycle 40
chr22_+_31518938 0.019 ENST00000412985.1
ENST00000331075.5
ENST00000412277.2
ENST00000420017.1
ENST00000400294.2
ENST00000405300.1
ENST00000404390.3
 INPP5J






inositol polyphosphate-5-phosphatase J






chr10_-_94257512 0.016 ENST00000371581.5
 IDE
insulin-degrading enzyme
chr16_-_87350970 0.016 ENST00000567970.1
 C16orf95
chromosome 16 open reading frame 95
chr4_+_110749143 0.012 ENST00000317735.4
 RRH
retinal pigment epithelium-derived rhodopsin homolog
chr11_+_2323236 0.009 ENST00000182290.4
 TSPAN32
tetraspanin 32
chr1_+_176432298 0.006 ENST00000367661.3
ENST00000367662.3
 PAPPA2

pappalysin 2

chr9_-_118687405 0.004 ENST00000374014.3
 LINC00474
long intergenic non-protein coding RNA 474
chr2_-_166060571 0.004 ENST00000360093.3
 SCN3A
sodium channel, voltage-gated, type III, alpha subunit
chr8_-_146176199 0.003 ENST00000532351.1
ENST00000276816.4
ENST00000394909.2
 ZNF16


zinc finger protein 16


chr17_-_40337470 0.001 ENST00000293330.1
 HCRT
hypocretin (orexin) neuropeptide precursor
chr1_-_47655686 0.001 ENST00000294338.2
 PDZK1IP1
PDZK1 interacting protein 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 GO:2000124 cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926) regulation of endocannabinoid signaling pathway(GO:2000124)
0.2 1.8 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.2 1.6 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 1.0 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 0.9 GO:0071731 response to nitric oxide(GO:0071731)
0.1 0.8 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 0.6 GO:0006465 signal peptide processing(GO:0006465)
0.1 0.5 GO:0019934 cGMP-mediated signaling(GO:0019934)
0.0 0.3 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.2 GO:0019985 translesion synthesis(GO:0019985)
0.0 0.8 GO:0042730 fibrinolysis(GO:0042730)
0.0 0.1 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.0 0.1 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.4 GO:0042554 superoxide anion generation(GO:0042554)
0.0 0.0 GO:1901642 purine nucleoside transmembrane transport(GO:0015860) purine-containing compound transmembrane transport(GO:0072530) nucleoside transmembrane transport(GO:1901642)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 1.0 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 0.2 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 0.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:0000145 exocyst(GO:0000145)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.2 1.6 GO:0008179 adenylate cyclase binding(GO:0008179)
0.2 0.8 GO:0045499 chemorepellent activity(GO:0045499)
0.1 1.0 GO:0031994 insulin-like growth factor I binding(GO:0031994)
0.1 1.4 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.5 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 0.4 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 1.8 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.1 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.0 GO:0015389 pyrimidine- and adenine-specific:sodium symporter activity(GO:0015389)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 ST_P38_MAPK_PATHWAY p38 MAPK Pathway