Motif ID: POU6F2
Z-value: 1.088
Transcription factors associated with POU6F2:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| POU6F2 | ENSG00000106536.15 | POU6F2 |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 1.4 | GO:0002082 | regulation of oxidative phosphorylation(GO:0002082) |
| 0.4 | 1.3 | GO:0035987 | endodermal cell fate commitment(GO:0001711) endodermal cell differentiation(GO:0035987) |
| 0.3 | 1.1 | GO:0010908 | regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) embryonic hindgut morphogenesis(GO:0048619) positive regulation of proteoglycan biosynthetic process(GO:1902730) |
| 0.2 | 1.7 | GO:0042420 | dopamine catabolic process(GO:0042420) |
| 0.2 | 1.0 | GO:0061003 | positive regulation of dendritic spine morphogenesis(GO:0061003) |
| 0.1 | 0.4 | GO:0019521 | aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521) |
| 0.1 | 0.6 | GO:0001302 | replicative cell aging(GO:0001302) female genitalia morphogenesis(GO:0048807) |
| 0.1 | 1.0 | GO:0034638 | phosphatidylcholine catabolic process(GO:0034638) |
| 0.1 | 0.3 | GO:0050917 | sensory perception of umami taste(GO:0050917) |
| 0.1 | 1.2 | GO:0006107 | oxaloacetate metabolic process(GO:0006107) |
| 0.1 | 0.5 | GO:0045953 | desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032) negative regulation of natural killer cell mediated immunity(GO:0002716) negative regulation of natural killer cell mediated cytotoxicity(GO:0045953) |
| 0.1 | 0.3 | GO:0021759 | globus pallidus development(GO:0021759) menarche(GO:0042696) |
| 0.1 | 0.2 | GO:0051541 | elastin metabolic process(GO:0051541) |
| 0.1 | 0.3 | GO:0021527 | spinal cord association neuron differentiation(GO:0021527) neuron fate determination(GO:0048664) |
| 0.1 | 0.2 | GO:0046621 | negative regulation of organ growth(GO:0046621) |
| 0.1 | 0.4 | GO:0010459 | negative regulation of heart rate(GO:0010459) |
| 0.1 | 0.2 | GO:0003099 | positive regulation of the force of heart contraction by chemical signal(GO:0003099) |
| 0.1 | 0.2 | GO:0060023 | soft palate development(GO:0060023) |
| 0.1 | 0.3 | GO:0021535 | cell migration in hindbrain(GO:0021535) |
| 0.0 | 0.1 | GO:0048670 | regulation of collateral sprouting(GO:0048670) |
| 0.0 | 0.2 | GO:0002331 | immature B cell differentiation(GO:0002327) pre-B cell differentiation(GO:0002329) pre-B cell allelic exclusion(GO:0002331) |
| 0.0 | 0.4 | GO:0046784 | viral mRNA export from host cell nucleus(GO:0046784) |
| 0.0 | 0.1 | GO:2000008 | regulation of protein localization to cell surface(GO:2000008) |
| 0.0 | 0.3 | GO:0033089 | positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400) |
| 0.0 | 0.2 | GO:0007100 | mitotic centrosome separation(GO:0007100) |
| 0.0 | 0.3 | GO:0006570 | tyrosine metabolic process(GO:0006570) |
| 0.0 | 0.1 | GO:0070254 | mucus secretion(GO:0070254) |
| 0.0 | 0.3 | GO:0048013 | ephrin receptor signaling pathway(GO:0048013) |
| 0.0 | 0.2 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
| 0.0 | 0.2 | GO:0045741 | positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) |
| 0.0 | 0.1 | GO:0051971 | positive regulation of transmission of nerve impulse(GO:0051971) |
| 0.0 | 0.5 | GO:0009954 | proximal/distal pattern formation(GO:0009954) |
| 0.0 | 0.5 | GO:0007398 | ectoderm development(GO:0007398) |
| 0.0 | 0.5 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
| 0.0 | 0.3 | GO:0007020 | microtubule nucleation(GO:0007020) |
| 0.0 | 0.5 | GO:0007417 | central nervous system development(GO:0007417) |
| 0.0 | 0.5 | GO:0043488 | regulation of mRNA stability(GO:0043488) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 1.1 | GO:0070369 | beta-catenin-TCF7L2 complex(GO:0070369) beta-catenin-TCF complex(GO:1990907) |
| 0.1 | 0.6 | GO:0019718 | obsolete rough microsome(GO:0019718) |
| 0.1 | 0.4 | GO:0097651 | phosphatidylinositol 3-kinase complex, class IA(GO:0005943) phosphatidylinositol 3-kinase complex, class I(GO:0097651) |
| 0.1 | 0.4 | GO:0000445 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
| 0.1 | 0.2 | GO:0033202 | Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202) INO80-type complex(GO:0097346) |
| 0.0 | 1.4 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
| 0.0 | 0.3 | GO:0033162 | melanosome membrane(GO:0033162) chitosome(GO:0045009) |
| 0.0 | 0.3 | GO:0005828 | kinetochore microtubule(GO:0005828) |
| 0.0 | 0.9 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
| 0.0 | 0.3 | GO:0012510 | trans-Golgi network transport vesicle membrane(GO:0012510) |
| 0.0 | 0.2 | GO:0098643 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
| 0.0 | 0.6 | GO:0042645 | mitochondrial nucleoid(GO:0042645) |
| 0.0 | 0.3 | GO:0000299 | obsolete integral to membrane of membrane fraction(GO:0000299) |
| 0.0 | 1.7 | GO:0005741 | mitochondrial outer membrane(GO:0005741) |
| 0.0 | 0.1 | GO:0060170 | ciliary membrane(GO:0060170) |
| 0.0 | 0.2 | GO:0016585 | obsolete chromatin remodeling complex(GO:0016585) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 1.2 | GO:0004613 | phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613) |
| 0.3 | 1.7 | GO:0008131 | primary amine oxidase activity(GO:0008131) |
| 0.1 | 2.5 | GO:0016500 | protein-hormone receptor activity(GO:0016500) |
| 0.1 | 0.6 | GO:0008649 | rRNA methyltransferase activity(GO:0008649) |
| 0.1 | 1.3 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
| 0.1 | 1.0 | GO:0034185 | apolipoprotein binding(GO:0034185) |
| 0.1 | 1.3 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.1 | 1.1 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
| 0.1 | 0.2 | GO:0030160 | GKAP/Homer scaffold activity(GO:0030160) |
| 0.1 | 0.4 | GO:0004616 | phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616) |
| 0.1 | 0.4 | GO:0043559 | insulin binding(GO:0043559) |
| 0.1 | 0.3 | GO:0017159 | pantetheine hydrolase activity(GO:0017159) GPI anchor binding(GO:0034235) |
| 0.1 | 0.3 | GO:0004167 | dopachrome isomerase activity(GO:0004167) |
| 0.1 | 0.2 | GO:0004937 | alpha1-adrenergic receptor activity(GO:0004937) |
| 0.0 | 0.5 | GO:0031701 | angiotensin receptor binding(GO:0031701) |
| 0.0 | 0.2 | GO:0016802 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
| 0.0 | 0.3 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
| 0.0 | 0.3 | GO:0008107 | galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127) |
| 0.0 | 0.2 | GO:0008454 | alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454) |
| 0.0 | 0.2 | GO:0030020 | extracellular matrix structural constituent conferring tensile strength(GO:0030020) |
| 0.0 | 0.3 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
| 0.0 | 0.2 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
| 0.0 | 0.5 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
| 0.0 | 1.4 | GO:0001067 | regulatory region DNA binding(GO:0000975) regulatory region nucleic acid binding(GO:0001067) transcription regulatory region DNA binding(GO:0044212) |
| 0.0 | 0.1 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
| 0.0 | 0.5 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
| 0.0 | 0.0 | GO:0008431 | vitamin E binding(GO:0008431) |
| 0.0 | 0.2 | GO:0008242 | omega peptidase activity(GO:0008242) |
| 0.0 | 0.5 | GO:0004890 | GABA-A receptor activity(GO:0004890) |
| 0.0 | 0.7 | GO:0017048 | Rho GTPase binding(GO:0017048) |
| 0.0 | 0.6 | GO:0002039 | p53 binding(GO:0002039) |
| 0.0 | 0.3 | GO:0005001 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
| 0.0 | 0.5 | GO:0097472 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472) |
| 0.0 | 0.1 | GO:0005078 | MAP-kinase scaffold activity(GO:0005078) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.2 | ST_ERK1_ERK2_MAPK_PATHWAY | ERK1/ERK2 MAPK Pathway |
| 0.0 | 0.6 | ST_B_CELL_ANTIGEN_RECEPTOR | B Cell Antigen Receptor |
