ISMARA results: PPARD

Motif ID: PPARD

Z-value: 0.823

Transcription factors associated with PPARD:

Gene Symbol	Entrez ID	Gene Name
PPARD	ENSG00000112033.9	PPARD

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr15_+_43985084	1.393	ENST00000434505.1 ENST00000411750.1	CKMT1A	creatine kinase, mitochondrial 1A
chr15_+_43885252	1.290	ENST00000453782.1 ENST00000300283.6 ENST00000437924.1 ENST00000450086.2	CKMT1B	creatine kinase, mitochondrial 1B
chr6_+_33172407	0.668	ENST00000374662.3	HSD17B8	hydroxysteroid (17-beta) dehydrogenase 8
chr4_+_174089904	0.637	ENST00000265000.4	GALNT7	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)
chr1_+_156123318	0.605	ENST00000368285.3	SEMA4A	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr19_+_10197463	0.542	ENST00000590378.1 ENST00000397881.3	C19orf66	chromosome 19 open reading frame 66
chr15_-_82555000	0.537	ENST00000557844.1 ENST00000359445.3 ENST00000268206.7	EFTUD1	elongation factor Tu GTP binding domain containing 1
chr19_-_10687983	0.520	ENST00000587069.1	AP1M2	adaptor-related protein complex 1, mu 2 subunit
chr19_-_10687907	0.520	ENST00000589348.1	AP1M2	adaptor-related protein complex 1, mu 2 subunit
chr19_+_10196981	0.494	ENST00000591813.1	C19orf66	chromosome 19 open reading frame 66
chr5_-_16509101	0.490	ENST00000399793.2	FAM134B	family with sequence similarity 134, member B
chr15_+_78441663	0.461	ENST00000299518.2 ENST00000558554.1 ENST00000557826.1 ENST00000561279.1 ENST00000559186.1 ENST00000560770.1 ENST00000559881.1 ENST00000559205.1 ENST00000441490.2	IDH3A	isocitrate dehydrogenase 3 (NAD+) alpha
chrX_-_148571884	0.460	ENST00000537071.1	IDS	iduronate 2-sulfatase
chr1_-_197036364	0.389	ENST00000367412.1	F13B	coagulation factor XIII, B polypeptide
chr3_-_48936272	0.377	ENST00000544097.1 ENST00000430379.1 ENST00000319017.4	SLC25A20	solute carrier family 25 (carnitine/acylcarnitine translocase), member 20
chr17_-_39728303	0.362	ENST00000588431.1 ENST00000246662.4	KRT9	keratin 9
chr8_-_80942467	0.338	ENST00000518271.1 ENST00000276585.4 ENST00000521605.1	MRPS28	mitochondrial ribosomal protein S28
chr9_+_126773880	0.335	ENST00000373615.4	LHX2	LIM homeobox 2
chr8_-_80942061	0.335	ENST00000519386.1	MRPS28	mitochondrial ribosomal protein S28
chr19_-_10687948	0.328	ENST00000592285.1	AP1M2	adaptor-related protein complex 1, mu 2 subunit
chr12_-_95467267	0.318	ENST00000330677.7	NR2C1	nuclear receptor subfamily 2, group C, member 1
chr8_-_80942139	0.297	ENST00000521434.1 ENST00000519120.1 ENST00000520946.1	MRPS28	mitochondrial ribosomal protein S28
chr16_+_2255710	0.287	ENST00000397124.1 ENST00000565250.1	MLST8	MTOR associated protein, LST8 homolog (S. cerevisiae)
chr22_-_51017084	0.273	ENST00000360719.2 ENST00000457250.1 ENST00000440709.1	CPT1B	carnitine palmitoyltransferase 1B (muscle)
chr22_-_51016846	0.268	ENST00000312108.7 ENST00000395650.2	CPT1B	carnitine palmitoyltransferase 1B (muscle)
chr11_-_119599794	0.267	ENST00000264025.3	PVRL1	poliovirus receptor-related 1 (herpesvirus entry mediator C)
chr11_-_116968987	0.266	ENST00000434315.2 ENST00000292055.4 ENST00000375288.1 ENST00000542607.1 ENST00000445177.1 ENST00000375300.1 ENST00000446921.2	SIK3	SIK family kinase 3
chr16_+_2255841	0.265	ENST00000301725.7	MLST8	MTOR associated protein, LST8 homolog (S. cerevisiae)
chr6_-_33547975	0.263	ENST00000442998.2 ENST00000360661.5	BAK1	BCL2-antagonist/killer 1
chr22_-_29784519	0.263	ENST00000357586.2 ENST00000356015.2 ENST00000432560.2 ENST00000317368.7	AP1B1	adaptor-related protein complex 1, beta 1 subunit
chr4_-_7069760	0.246	ENST00000264954.4	GRPEL1	GrpE-like 1, mitochondrial (E. coli)
chr6_-_33548006	0.240	ENST00000374467.3	BAK1	BCL2-antagonist/killer 1
chr22_+_30163340	0.237	ENST00000330029.6 ENST00000401406.3	UQCR10	ubiquinol-cytochrome c reductase, complex III subunit X
chr17_+_48610074	0.237	ENST00000503690.1 ENST00000514874.1 ENST00000537145.1 ENST00000541226.1	EPN3	epsin 3
chr11_+_64073699	0.230	ENST00000405666.1 ENST00000468670.1	ESRRA	estrogen-related receptor alpha
chr2_+_219433281	0.221	ENST00000273064.6 ENST00000509807.2 ENST00000542068.1	RQCD1	RCD1 required for cell differentiation1 homolog (S. pombe)
chr19_-_3062465	0.217	ENST00000327141.4	AES	amino-terminal enhancer of split
chr19_+_17420340	0.213	ENST00000359866.4	DDA1	DET1 and DDB1 associated 1
chr1_-_29508321	0.212	ENST00000546138.1	SRSF4	serine/arginine-rich splicing factor 4
chr16_+_81272287	0.207	ENST00000425577.2 ENST00000564552.1	BCMO1	beta-carotene 15,15'-monooxygenase 1
chr16_-_4401258	0.191	ENST00000577031.1	PAM16	presequence translocase-associated motor 16 homolog (S. cerevisiae)
chr11_-_45939565	0.190	ENST00000525192.1 ENST00000378750.5	PEX16	peroxisomal biogenesis factor 16
chr11_-_45939374	0.181	ENST00000533151.1 ENST00000241041.3	PEX16	peroxisomal biogenesis factor 16
chrX_-_108868390	0.180	ENST00000372101.2	KCNE1L	KCNE1-like
chr15_+_75494214	0.167	ENST00000394987.4	C15orf39	chromosome 15 open reading frame 39
chr1_-_161102421	0.165	ENST00000490843.2 ENST00000368006.3 ENST00000392188.1 ENST00000545495.1	DEDD	death effector domain containing
chr19_+_39616410	0.156	ENST00000602004.1 ENST00000599470.1 ENST00000321944.4 ENST00000593480.1 ENST00000358301.3 ENST00000593690.1 ENST00000599386.1	PAK4	p21 protein (Cdc42/Rac)-activated kinase 4
chr1_-_161102367	0.146	ENST00000464113.1	DEDD	death effector domain containing
chr1_-_11107280	0.142	ENST00000400897.3 ENST00000400898.3	MASP2	mannan-binding lectin serine peptidase 2
chr20_-_44485835	0.138	ENST00000457981.1 ENST00000426915.1 ENST00000217455.4	ACOT8	acyl-CoA thioesterase 8
chr20_+_46130601	0.137	ENST00000341724.6	NCOA3	nuclear receptor coactivator 3
chr11_+_17281900	0.137	ENST00000530527.1	NUCB2	nucleobindin 2
chr12_+_60058458	0.129	ENST00000548610.1	SLC16A7	solute carrier family 16 (monocarboxylate transporter), member 7
chr1_+_165864800	0.127	ENST00000469256.2	UCK2	uridine-cytidine kinase 2
chr10_-_103815874	0.124	ENST00000370033.4 ENST00000311122.5	C10orf76	chromosome 10 open reading frame 76
chr12_+_121163538	0.119	ENST00000242592.4	ACADS	acyl-CoA dehydrogenase, C-2 to C-3 short chain
chr3_+_48507210	0.118	ENST00000433541.1 ENST00000422277.2 ENST00000436480.2 ENST00000444177.1	TREX1	three prime repair exonuclease 1
chr10_+_94050913	0.117	ENST00000358935.2	MARCH5	membrane-associated ring finger (C3HC4) 5
chr2_+_206547215	0.113	ENST00000360409.3 ENST00000540178.1 ENST00000540841.1 ENST00000355117.4 ENST00000450507.1 ENST00000417189.1	NRP2	neuropilin 2
chr6_+_30594619	0.113	ENST00000318999.7 ENST00000376485.4 ENST00000376478.2 ENST00000319027.5 ENST00000376483.4 ENST00000329992.8 ENST00000330083.5	ATAT1	alpha tubulin acetyltransferase 1
chr17_+_7483761	0.112	ENST00000584180.1	CD68	CD68 molecule
chr12_+_96252706	0.111	ENST00000266735.5 ENST00000553192.1 ENST00000552085.1	SNRPF	small nuclear ribonucleoprotein polypeptide F
chr3_-_187009798	0.105	ENST00000337774.5	MASP1	mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
chr21_-_27107198	0.104	ENST00000400094.1	ATP5J	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
chr4_+_140586922	0.101	ENST00000265498.1 ENST00000506797.1	MGST2	microsomal glutathione S-transferase 2
chr3_+_186383741	0.098	ENST00000232003.4	HRG	histidine-rich glycoprotein
chrX_+_2746818	0.096	ENST00000398806.3	GYG2	glycogenin 2
chr20_+_42187682	0.088	ENST00000373092.3 ENST00000373077.1	SGK2	serum/glucocorticoid regulated kinase 2
chr1_+_159175201	0.086	ENST00000368121.2	DARC	Duffy blood group, atypical chemokine receptor
chr16_-_4401284	0.085	ENST00000318059.3	PAM16	presequence translocase-associated motor 16 homolog (S. cerevisiae)
chr1_+_165864821	0.085	ENST00000470820.1	UCK2	uridine-cytidine kinase 2
chr20_+_42187608	0.084	ENST00000373100.1	SGK2	serum/glucocorticoid regulated kinase 2
chr21_-_27107283	0.078	ENST00000284971.3 ENST00000400099.1	ATP5J	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
chr1_+_55107449	0.072	ENST00000421030.2 ENST00000545244.1 ENST00000339553.5 ENST00000409996.1 ENST00000454855.2	MROH7	maestro heat-like repeat family member 7
chr12_-_21757774	0.070	ENST00000261195.2	GYS2	glycogen synthase 2 (liver)
chr6_+_43265992	0.067	ENST00000449231.1 ENST00000372589.3 ENST00000372585.5	SLC22A7	solute carrier family 22 (organic anion transporter), member 7
chr21_-_27107344	0.066	ENST00000457143.2	ATP5J	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
chr21_+_27107672	0.062	ENST00000400075.3	GABPA	GA binding protein transcription factor, alpha subunit 60kDa
chr2_+_178257372	0.059	ENST00000264167.4 ENST00000409888.1	AGPS	alkylglycerone phosphate synthase
chr12_-_56727487	0.058	ENST00000548043.1 ENST00000425394.2	PAN2	PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr1_-_160832642	0.053	ENST00000368034.4	CD244	CD244 molecule, natural killer cell receptor 2B4
chr21_-_27107881	0.053	ENST00000400090.3 ENST00000400087.3 ENST00000400093.3	ATP5J	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
chr12_-_53320245	0.046	ENST00000552150.1	KRT8	keratin 8
chr1_-_120311517	0.043	ENST00000369406.3 ENST00000544913.2	HMGCS2	3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
chr6_+_88299833	0.041	ENST00000392844.3 ENST00000257789.4 ENST00000546266.1 ENST00000417380.2	ORC3	origin recognition complex, subunit 3
chr4_+_159593271	0.037	ENST00000512251.1 ENST00000511912.1	ETFDH	electron-transferring-flavoprotein dehydrogenase
chr16_-_74808710	0.033	ENST00000219368.3 ENST00000544337.1	FA2H	fatty acid 2-hydroxylase
chrX_+_38211777	0.032	ENST00000039007.4	OTC	ornithine carbamoyltransferase
chr1_+_9005917	0.028	ENST00000549778.1 ENST00000480186.3 ENST00000377443.2 ENST00000377436.3 ENST00000377442.2	CA6	carbonic anhydrase VI
chr1_-_11863171	0.026	ENST00000376592.1	MTHFR	methylenetetrahydrofolate reductase (NAD(P)H)
chr11_-_61658853	0.019	ENST00000525588.1 ENST00000540820.1	FADS3	fatty acid desaturase 3
chr19_+_49867181	0.016	ENST00000597546.1	DKKL1	dickkopf-like 1
chr1_+_62417957	0.011	ENST00000307297.7 ENST00000543708.1	INADL	InaD-like (Drosophila)
chr6_+_43266063	0.000	ENST00000372574.3	SLC22A7	solute carrier family 22 (organic anion transporter), member 7
chr3_-_125094093	0.000	ENST00000484491.1 ENST00000492394.1 ENST00000471196.1 ENST00000468369.1 ENST00000544464.1 ENST00000485866.1 ENST00000360647.4	ZNF148	zinc finger protein 148
chr6_+_72922505	0.000	ENST00000401910.3	RIMS1	regulating synaptic membrane exocytosis 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient(GO:0010248) post-embryonic camera-type eye development(GO:0031077)
0.1	0.4	GO:0032581	ER-dependent peroxisome organization(GO:0032581)
0.1	1.3	GO:0006600	creatine metabolic process(GO:0006600)
0.1	0.7	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.1	0.5	GO:0006102	isocitrate metabolic process(GO:0006102)
0.1	0.2	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1	0.9	GO:1902603	carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603)
0.0	0.3	GO:0021978	telencephalon regionalization(GO:0021978)
0.0	0.4	GO:0045109	intermediate filament organization(GO:0045109)
0.0	0.6	GO:0032008	positive regulation of TOR signaling(GO:0032008)
0.0	1.6	GO:0050690	regulation of defense response to virus by virus(GO:0050690)
0.0	0.1	GO:0006848	pyruvate transport(GO:0006848)
0.0	0.1	GO:0019605	butyrate metabolic process(GO:0019605)
0.0	0.6	GO:0006493	protein O-linked glycosylation(GO:0006493)
0.0	0.3	GO:0046718	viral entry into host cell(GO:0046718)
0.0	0.3	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191)
0.0	0.2	GO:0043097	pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0	0.1	GO:0000266	mitochondrial fission(GO:0000266)
0.0	0.5	GO:1990542	mitochondrial transmembrane transport(GO:1990542)
0.0	0.0	GO:0070781	response to biotin(GO:0070781)
0.0	0.0	GO:0043441	acetoacetic acid biosynthetic process(GO:0043441)
0.0	0.1	GO:0001867	complement activation, lectin pathway(GO:0001867)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0032584	growth cone membrane(GO:0032584)
0.1	1.0	GO:0005763	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0	1.6	GO:0030131	clathrin adaptor complex(GO:0030131)
0.0	0.3	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0	0.5	GO:0046930	pore complex(GO:0046930)
0.0	0.1	GO:0005797	Golgi medial cisterna(GO:0005797)
0.0	0.5	GO:0005801	cis-Golgi network(GO:0005801)
0.0	0.4	GO:0031231	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0	0.1	GO:0005683	U7 snRNP(GO:0005683)
0.0	0.4	GO:0045095	keratin filament(GO:0045095)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.3	GO:0004111	creatine kinase activity(GO:0004111)
0.1	0.5	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1	0.5	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.1	0.7	GO:0047035	testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.1	0.4	GO:0015651	quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.1	0.5	GO:0051400	BH domain binding(GO:0051400)
0.0	0.6	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.2	GO:0016681	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0	0.3	GO:0046790	virion binding(GO:0046790)
0.0	0.1	GO:0050833	pyruvate secondary active transmembrane transporter activity(GO:0005477) pyruvate transmembrane transporter activity(GO:0050833)
0.0	0.2	GO:0004849	uridine kinase activity(GO:0004849)
0.0	0.1	GO:0032558	purine deoxyribonucleotide binding(GO:0032554) adenyl deoxyribonucleotide binding(GO:0032558)
0.0	0.5	GO:0008484	sulfuric ester hydrolase activity(GO:0008484)
0.0	0.2	GO:0060590	ATPase regulator activity(GO:0060590)
0.0	0.1	GO:0019956	chemokine binding(GO:0019956)
0.0	0.5	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	0.2	GO:0017080	sodium channel regulator activity(GO:0017080)
0.0	0.0	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.0	0.1	GO:0047617	acyl-CoA hydrolase activity(GO:0047617)