Motif ID: PRDM4

Z-value: 0.885


Transcription factors associated with PRDM4:

Gene SymbolEntrez IDGene Name
PRDM4 ENSG00000110851.7 PRDM4



Activity profile for motif PRDM4.

activity profile for motif PRDM4


Sorted Z-values histogram for motif PRDM4

Sorted Z-values for motif PRDM4



Network of associatons between targets according to the STRING database.



First level regulatory network of PRDM4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_+_105953204 1.208 ENST00000409393.2
 CRIP1
cysteine-rich protein 1 (intestinal)
chr14_+_105953246 1.154 ENST00000392531.3
 CRIP1
cysteine-rich protein 1 (intestinal)
chr12_-_58240470 0.901 ENST00000548823.1
ENST00000398073.2
 CTDSP2

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2

chr3_+_16926441 0.821 ENST00000418129.2
ENST00000396755.2
 PLCL2

phospholipase C-like 2

chr20_+_62697564 0.807 ENST00000458442.1
 TCEA2
transcription elongation factor A (SII), 2
chr9_-_16727978 0.796 ENST00000418777.1
ENST00000468187.2
 BNC2

basonuclin 2

chr10_-_105212141 0.761 ENST00000369788.3
 CALHM2
calcium homeostasis modulator 2
chr4_+_667686 0.681 ENST00000505477.1
 MYL5
myosin, light chain 5, regulatory
chr17_+_42634844 0.671 ENST00000315323.3
 FZD2
frizzled family receptor 2
chr22_+_38864041 0.653 ENST00000216014.4
ENST00000409006.3
 KDELR3

KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3

chr1_-_43232649 0.592 ENST00000372526.2
ENST00000236040.4
ENST00000296388.5
ENST00000397054.3
 LEPRE1



leucine proline-enriched proteoglycan (leprecan) 1



chr12_+_104682496 0.558 ENST00000378070.4
 TXNRD1
thioredoxin reductase 1
chr4_+_667307 0.546 ENST00000506838.1
 MYL5
myosin, light chain 5, regulatory
chr3_+_148709128 0.472 ENST00000345003.4
ENST00000296048.6
ENST00000483267.1
 GYG1


glycogenin 1


chr3_+_148709310 0.424 ENST00000484197.1
ENST00000492285.2
ENST00000461191.1
 GYG1


glycogenin 1


chr20_-_61569296 0.405 ENST00000370371.4
 DIDO1
death inducer-obliterator 1
chr14_+_24025194 0.351 ENST00000404535.3
ENST00000288014.6
 THTPA

thiamine triphosphatase

chr19_-_53636125 0.318 ENST00000601493.1
ENST00000599261.1
ENST00000597503.1
ENST00000500065.4
ENST00000243643.4
ENST00000594011.1
ENST00000455735.2
ENST00000595193.1
ENST00000448501.1
ENST00000421033.1
ENST00000440291.1
ENST00000595813.1
ENST00000600574.1
ENST00000596051.1
ENST00000601110.1
 ZNF415














zinc finger protein 415














chr7_+_143079000 0.311 ENST00000392910.2
 ZYX
zyxin
chr10_+_123923105 0.289 ENST00000368999.1
 TACC2
transforming, acidic coiled-coil containing protein 2
chr5_-_78281603 0.276 ENST00000264914.4
 ARSB
arylsulfatase B
chr7_+_90893783 0.241 ENST00000287934.2
 FZD1
frizzled family receptor 1
chr6_-_32160622 0.196 ENST00000487761.1
ENST00000375040.3
 GPSM3

G-protein signaling modulator 3

chr1_+_172502336 0.188 ENST00000263688.3
 SUCO
SUN domain containing ossification factor
chr7_+_143078652 0.171 ENST00000354434.4
ENST00000449423.2
 ZYX

zyxin

chr9_+_96338647 0.165 ENST00000359246.4
 PHF2
PHD finger protein 2
chr19_+_42724423 0.155 ENST00000301215.3
ENST00000597945.1
 ZNF526

zinc finger protein 526

chr17_-_9929581 0.151 ENST00000437099.2
ENST00000396115.2
 GAS7

growth arrest-specific 7

chr6_+_26045603 0.130 ENST00000540144.1
 HIST1H3C
histone cluster 1, H3c
chr19_-_49371711 0.124 ENST00000355496.5
ENST00000263265.6
 PLEKHA4

pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4

chr1_+_43232913 0.115 ENST00000372525.5
ENST00000536543.1
 C1orf50

chromosome 1 open reading frame 50

chr17_+_7788104 0.114 ENST00000380358.4
 CHD3
chromodomain helicase DNA binding protein 3
chr2_+_234296792 0.108 ENST00000409813.3
 DGKD
diacylglycerol kinase, delta 130kDa
chr19_+_50180317 0.104 ENST00000534465.1
 PRMT1
protein arginine methyltransferase 1
chr1_+_27114589 0.103 ENST00000431541.1
ENST00000449950.2
ENST00000374145.1
 PIGV


phosphatidylinositol glycan anchor biosynthesis, class V


chr6_-_8064567 0.102 ENST00000543936.1
ENST00000397457.2
 BLOC1S5

biogenesis of lysosomal organelles complex-1, subunit 5, muted

chr2_+_219264466 0.100 ENST00000273062.2
 CTDSP1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr20_-_61569227 0.091 ENST00000266070.4
ENST00000395335.2
ENST00000266071.5
 DIDO1


death inducer-obliterator 1


chr5_+_102455968 0.085 ENST00000358359.3
 PPIP5K2
diphosphoinositol pentakisphosphate kinase 2
chr1_+_27114418 0.081 ENST00000078527.4
 PIGV
phosphatidylinositol glycan anchor biosynthesis, class V
chr5_-_180688105 0.069 ENST00000327767.4
 TRIM52
tripartite motif containing 52
chr7_-_23571586 0.056 ENST00000538367.1
ENST00000392502.4
ENST00000297071.4
 TRA2A


transformer 2 alpha homolog (Drosophila)


chrX_+_15808569 0.055 ENST00000380308.3
ENST00000307771.7
 ZRSR2

zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2

chr9_-_127263265 0.046 ENST00000373587.3
 NR5A1
nuclear receptor subfamily 5, group A, member 1
chr11_+_58910295 0.031 ENST00000420244.1
 FAM111A
family with sequence similarity 111, member A
chr9_+_17135016 0.023 ENST00000425824.1
ENST00000262360.5
ENST00000380641.4
 CNTLN


centlein, centrosomal protein


chr5_+_102455853 0.013 ENST00000515845.1
ENST00000321521.9
ENST00000507921.1
 PPIP5K2


diphosphoinositol pentakisphosphate kinase 2


chr2_-_8723918 0.013 ENST00000454224.1
 AC011747.4
AC011747.4
chr16_+_15068955 0.011 ENST00000396410.4
ENST00000569715.1
ENST00000450288.2
 PDXDC1


pyridoxal-dependent decarboxylase domain containing 1


chr19_-_51471381 0.010 ENST00000594641.1
 KLK6
kallikrein-related peptidase 6
chr12_+_15475331 0.008 ENST00000281171.4
 PTPRO
protein tyrosine phosphatase, receptor type, O
chr10_+_88728189 0.002 ENST00000416348.1
 ADIRF
adipogenesis regulatory factor
chr19_-_51471362 0.001 ENST00000376853.4
ENST00000424910.2
 KLK6

kallikrein-related peptidase 6

chr12_+_15475462 0.000 ENST00000543886.1
ENST00000348962.2
 PTPRO

protein tyrosine phosphatase, receptor type, O


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0090047 obsolete positive regulation of transcription regulator activity(GO:0090047)
0.1 0.7 GO:0006621 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.1 0.4 GO:0006772 thiamine metabolic process(GO:0006772)
0.1 0.2 GO:0061188 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.0 0.8 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.0 0.2 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.3 GO:0051597 response to methylmercury(GO:0051597)
0.0 0.8 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 0.1 GO:0060968 regulation of gene silencing(GO:0060968)
0.0 0.6 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.0 0.1 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.0 GO:0007538 primary sex determination(GO:0007538)
0.0 0.1 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.1 GO:0006020 inositol metabolic process(GO:0006020)
0.0 1.2 GO:0006937 regulation of muscle contraction(GO:0006937)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.9 GO:0032589 neuron projection membrane(GO:0032589)
0.0 0.8 GO:0008023 transcription elongation factor complex(GO:0008023)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0008420 CTD phosphatase activity(GO:0008420)
0.2 0.9 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.2 0.6 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.1 0.6 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.1 0.7 GO:0046923 ER retention sequence binding(GO:0046923)
0.1 0.2 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.1 0.8 GO:0003711 obsolete transcription elongation regulator activity(GO:0003711)
0.0 0.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.8 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.1 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.3 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.1 GO:0000827 inositol-1,3,4,5,6-pentakisphosphate kinase activity(GO:0000827) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.1 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.4 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 1.2 GO:0008307 structural constituent of muscle(GO:0008307)