Motif ID: RARA

Z-value: 1.446


Transcription factors associated with RARA:

Gene SymbolEntrez IDGene Name
RARA ENSG00000131759.13 RARA



Activity profile for motif RARA.

activity profile for motif RARA


Sorted Z-values histogram for motif RARA

Sorted Z-values for motif RARA



Network of associatons between targets according to the STRING database.



First level regulatory network of RARA

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_+_33010175 5.094 ENST00000300177.4
ENST00000560677.1
ENST00000560830.1
GREM1


gremlin 1, DAN family BMP antagonist


chr3_-_55521323 2.686 ENST00000264634.4
WNT5A
wingless-type MMTV integration site family, member 5A
chr2_-_151344172 2.613 ENST00000375734.2
ENST00000263895.4
ENST00000454202.1
RND3


Rho family GTPase 3


chr1_-_95007193 2.373 ENST00000370207.4
ENST00000334047.7
F3

coagulation factor III (thromboplastin, tissue factor)

chr9_-_21995300 2.296 ENST00000498628.2
CDKN2A
cyclin-dependent kinase inhibitor 2A
chr10_+_88728189 2.283 ENST00000416348.1
ADIRF
adipogenesis regulatory factor
chr2_-_235405679 2.019 ENST00000390645.2
ARL4C
ADP-ribosylation factor-like 4C
chr11_+_10326612 1.704 ENST00000534464.1
ENST00000530439.1
ENST00000524948.1
ENST00000528655.1
ENST00000526492.1
ENST00000525063.1
ADM





adrenomedullin





chr1_-_93426998 1.660 ENST00000370310.4
FAM69A
family with sequence similarity 69, member A
chr9_-_21995249 1.632 ENST00000494262.1
CDKN2A
cyclin-dependent kinase inhibitor 2A
chr9_-_21994344 1.516 ENST00000530628.2
ENST00000361570.3
CDKN2A

cyclin-dependent kinase inhibitor 2A

chr9_+_124030338 1.472 ENST00000449773.1
ENST00000432226.1
ENST00000436847.1
ENST00000394353.2
ENST00000449733.1
ENST00000412819.1
ENST00000341272.2
ENST00000373808.2
GSN







gelsolin







chr9_-_21994597 1.468 ENST00000579755.1
CDKN2A
cyclin-dependent kinase inhibitor 2A
chr6_-_46459099 1.456 ENST00000371374.1
RCAN2
regulator of calcineurin 2
chr9_+_139873264 1.418 ENST00000446677.1
PTGDS
prostaglandin D2 synthase 21kDa (brain)
chr13_+_43597269 1.383 ENST00000379221.2
DNAJC15
DnaJ (Hsp40) homolog, subfamily C, member 15
chr1_-_156675368 1.378 ENST00000368222.3
CRABP2
cellular retinoic acid binding protein 2
chr10_+_17270214 1.326 ENST00000544301.1
VIM
vimentin
chr10_-_126849588 1.288 ENST00000411419.2
CTBP2
C-terminal binding protein 2
chr8_+_37654693 1.242 ENST00000412232.2
GPR124
G protein-coupled receptor 124
chr7_-_45960850 1.173 ENST00000381083.4
ENST00000381086.5
ENST00000275521.6
IGFBP3


insulin-like growth factor binding protein 3


chr12_+_54378923 1.158 ENST00000303460.4
HOXC10
homeobox C10
chr3_+_45067659 1.157 ENST00000296130.4
CLEC3B
C-type lectin domain family 3, member B
chr1_-_156647189 1.116 ENST00000368223.3
NES
nestin
chr17_-_80291818 0.937 ENST00000269389.3
ENST00000581691.1
SECTM1

secreted and transmembrane 1

chr19_+_35168633 0.918 ENST00000505365.2
ZNF302
zinc finger protein 302
chr19_+_35168567 0.917 ENST00000457781.2
ENST00000505163.1
ENST00000505242.1
ENST00000423823.2
ENST00000507959.1
ENST00000446502.2
ZNF302





zinc finger protein 302





chr10_+_43633914 0.914 ENST00000374466.3
ENST00000374464.1
CSGALNACT2

chondroitin sulfate N-acetylgalactosaminyltransferase 2

chr10_+_89419370 0.890 ENST00000361175.4
ENST00000456849.1
PAPSS2

3'-phosphoadenosine 5'-phosphosulfate synthase 2

chrX_-_37706815 0.879 ENST00000378578.4
DYNLT3
dynein, light chain, Tctex-type 3
chr19_+_16435625 0.847 ENST00000248071.5
ENST00000592003.1
KLF2

Kruppel-like factor 2

chr8_+_70404996 0.833 ENST00000402687.4
ENST00000419716.3
SULF1

sulfatase 1

chrX_+_51486481 0.823 ENST00000340438.4
GSPT2
G1 to S phase transition 2
chr1_-_33168336 0.822 ENST00000373484.3
SYNC
syncoilin, intermediate filament protein
chr19_-_43269809 0.792 ENST00000406636.3
ENST00000404209.4
ENST00000306511.4
PSG8


pregnancy specific beta-1-glycoprotein 8


chr9_-_21335356 0.753 ENST00000359039.4
KLHL9
kelch-like family member 9
chr6_+_7541845 0.725 ENST00000418664.2
DSP
desmoplakin
chr6_-_31324943 0.722 ENST00000412585.2
ENST00000434333.1
HLA-B

major histocompatibility complex, class I, B

chr11_-_8986474 0.721 ENST00000525069.1
TMEM9B
TMEM9 domain family, member B
chr1_-_16939976 0.712 ENST00000430580.2
NBPF1
neuroblastoma breakpoint family, member 1
chr1_+_26606608 0.705 ENST00000319041.6
SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3
chr19_-_58662139 0.694 ENST00000598312.1
ZNF329
zinc finger protein 329
chr7_-_81399438 0.672 ENST00000222390.5
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr4_+_154125565 0.670 ENST00000338700.5
TRIM2
tripartite motif containing 2
chr5_-_131562935 0.665 ENST00000379104.2
ENST00000379100.2
ENST00000428369.1
P4HA2


prolyl 4-hydroxylase, alpha polypeptide II


chr9_+_114393634 0.663 ENST00000556107.1
ENST00000374294.3
DNAJC25
DNAJC25-GNG10
DnaJ (Hsp40) homolog, subfamily C , member 25
DNAJC25-GNG10 readthrough
chr9_-_21335240 0.659 ENST00000537938.1
KLHL9
kelch-like family member 9
chr11_-_8985927 0.655 ENST00000528117.1
ENST00000309134.5
TMEM9B

TMEM9 domain family, member B

chr5_-_131563501 0.655 ENST00000401867.1
ENST00000379086.1
ENST00000418055.1
ENST00000453286.1
ENST00000166534.4
P4HA2




prolyl 4-hydroxylase, alpha polypeptide II




chr7_-_76247617 0.653 ENST00000441393.1
POMZP3
POM121 and ZP3 fusion
chr16_-_11680791 0.647 ENST00000571976.1
ENST00000413364.2
LITAF

lipopolysaccharide-induced TNF factor

chr10_+_115438920 0.620 ENST00000429617.1
ENST00000369331.4
CASP7

caspase 7, apoptosis-related cysteine peptidase

chr8_-_57358432 0.607 ENST00000517415.1
ENST00000314922.3
PENK

proenkephalin

chr3_+_13590636 0.607 ENST00000295760.7
FBLN2
fibulin 2
chr11_-_8986279 0.599 ENST00000534025.1
TMEM9B
TMEM9 domain family, member B
chr8_+_104152922 0.595 ENST00000309982.5
ENST00000438105.2
ENST00000297574.6
BAALC


brain and acute leukemia, cytoplasmic


chr10_+_120967072 0.588 ENST00000392870.2
GRK5
G protein-coupled receptor kinase 5
chrX_-_21776281 0.584 ENST00000379494.3
SMPX
small muscle protein, X-linked
chr11_-_18610275 0.582 ENST00000543987.1
UEVLD
UEV and lactate/malate dehyrogenase domains
chr19_-_39390440 0.565 ENST00000249396.7
ENST00000414941.1
ENST00000392081.2
SIRT2


sirtuin 2


chrX_-_102319092 0.561 ENST00000372728.3
BEX1
brain expressed, X-linked 1
chr15_-_65360450 0.543 ENST00000220062.4
RASL12
RAS-like, family 12
chr11_+_101983176 0.535 ENST00000524575.1
YAP1
Yes-associated protein 1
chr16_-_11680759 0.528 ENST00000571459.1
ENST00000570798.1
ENST00000572255.1
ENST00000574763.1
ENST00000574703.1
ENST00000571277.1
ENST00000381810.3
LITAF






lipopolysaccharide-induced TNF factor






chr22_+_50312379 0.527 ENST00000407217.3
ENST00000403427.3
CRELD2

cysteine-rich with EGF-like domains 2

chrX_-_48958043 0.522 ENST00000356463.3
WDR45
WD repeat domain 45
chr6_-_57086200 0.507 ENST00000468148.1
RAB23
RAB23, member RAS oncogene family
chrX_+_54835493 0.497 ENST00000396224.1
MAGED2
melanoma antigen family D, 2
chr5_+_131593364 0.496 ENST00000253754.3
ENST00000379018.3
PDLIM4

PDZ and LIM domain 4

chr3_+_43732362 0.495 ENST00000458276.2
ABHD5
abhydrolase domain containing 5
chr11_-_18610214 0.494 ENST00000300038.7
ENST00000396197.3
ENST00000320750.6
UEVLD


UEV and lactate/malate dehyrogenase domains


chr1_+_43855560 0.490 ENST00000562955.1
SZT2
seizure threshold 2 homolog (mouse)
chr20_+_60174827 0.486 ENST00000543233.1
CDH4
cadherin 4, type 1, R-cadherin (retinal)
chr22_+_50312316 0.478 ENST00000328268.4
CRELD2
cysteine-rich with EGF-like domains 2
chr19_-_39390350 0.474 ENST00000447739.1
ENST00000358931.5
ENST00000407552.1
SIRT2


sirtuin 2


chr19_+_8478154 0.473 ENST00000381035.4
ENST00000595142.1
ENST00000601724.1
ENST00000393944.1
ENST00000215555.2
ENST00000601283.1
ENST00000595213.1
MARCH2






membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase






chr7_-_81399411 0.468 ENST00000423064.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr2_+_85132749 0.467 ENST00000233143.4
TMSB10
thymosin beta 10
chr3_-_142608001 0.465 ENST00000295992.3
PCOLCE2
procollagen C-endopeptidase enhancer 2
chr20_+_43160409 0.459 ENST00000372894.3
ENST00000372892.3
ENST00000372891.3
PKIG


protein kinase (cAMP-dependent, catalytic) inhibitor gamma


chr18_+_21529811 0.450 ENST00000588004.1
LAMA3
laminin, alpha 3
chr5_-_114961858 0.445 ENST00000456936.3
ENST00000408996.4
ENST00000282382.4
TMED7
TICAM2
TMED7-TICAM2
transmembrane emp24 protein transport domain containing 7
toll-like receptor adaptor molecule 2
TMED7-TICAM2 readthrough
chr7_+_143079000 0.433 ENST00000392910.2
ZYX
zyxin
chr2_-_113594279 0.431 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
IL1B


interleukin 1, beta


chr11_-_44971702 0.429 ENST00000533940.1
ENST00000533937.1
TP53I11

tumor protein p53 inducible protein 11

chr5_-_55290773 0.429 ENST00000502326.3
ENST00000381298.2
IL6ST

interleukin 6 signal transducer (gp130, oncostatin M receptor)

chrX_-_13956737 0.425 ENST00000454189.2
GPM6B
glycoprotein M6B
chr19_+_49458107 0.415 ENST00000539787.1
ENST00000345358.7
ENST00000391871.3
ENST00000415969.2
ENST00000354470.3
ENST00000506183.1
ENST00000293288.8
BAX






BCL2-associated X protein






chr7_-_105752971 0.415 ENST00000011473.2
SYPL1
synaptophysin-like 1
chr11_-_2906979 0.415 ENST00000380725.1
ENST00000313407.6
ENST00000430149.2
ENST00000440480.2
ENST00000414822.3
CDKN1C




cyclin-dependent kinase inhibitor 1C (p57, Kip2)




chr11_+_114310237 0.408 ENST00000539119.1
REXO2
RNA exonuclease 2
chr12_+_5541267 0.401 ENST00000423158.3
NTF3
neurotrophin 3
chr7_+_143078652 0.392 ENST00000354434.4
ENST00000449423.2
ZYX

zyxin

chr22_+_47158578 0.388 ENST00000355704.3
TBC1D22A
TBC1 domain family, member 22A
chr11_+_114310164 0.384 ENST00000544196.1
ENST00000539754.1
ENST00000539275.1
REXO2


RNA exonuclease 2


chrX_-_1571810 0.384 ENST00000381333.4
ASMTL
acetylserotonin O-methyltransferase-like
chr3_+_133292574 0.382 ENST00000264993.3
CDV3
CDV3 homolog (mouse)
chr11_-_506739 0.382 ENST00000529306.1
ENST00000438658.2
ENST00000527485.1
ENST00000397615.2
ENST00000397614.1
RNH1




ribonuclease/angiogenin inhibitor 1




chr11_+_44117741 0.381 ENST00000395673.3
ENST00000343631.3
EXT2

exostosin glycosyltransferase 2

chr11_-_18610246 0.380 ENST00000379387.4
ENST00000541984.1
UEVLD

UEV and lactate/malate dehyrogenase domains

chr22_+_38302285 0.372 ENST00000215957.6
MICALL1
MICAL-like 1
chr3_-_142607740 0.369 ENST00000485766.1
PCOLCE2
procollagen C-endopeptidase enhancer 2
chr4_+_159593418 0.366 ENST00000507475.1
ENST00000307738.5
ETFDH

electron-transferring-flavoprotein dehydrogenase

chrX_+_100878079 0.365 ENST00000471229.2
ARMCX3
armadillo repeat containing, X-linked 3
chr9_-_139891165 0.357 ENST00000494426.1
CLIC3
chloride intracellular channel 3
chr9_+_21802542 0.347 ENST00000380172.4
MTAP
methylthioadenosine phosphorylase
chr22_+_47158518 0.337 ENST00000337137.4
ENST00000380995.1
ENST00000407381.3
TBC1D22A


TBC1 domain family, member 22A


chr3_+_118905564 0.330 ENST00000460625.1
UPK1B
uroplakin 1B
chr19_-_12780211 0.326 ENST00000598732.1
ENST00000222190.5
ENST00000597961.1
WDR83OS

CTD-2192J16.24
WD repeat domain 83 opposite strand

Uncharacterized protein
chrX_-_1571759 0.322 ENST00000381317.3
ENST00000416733.2
ASMTL

acetylserotonin O-methyltransferase-like

chr15_+_80351977 0.314 ENST00000559157.1
ENST00000561012.1
ENST00000564367.1
ENST00000558494.1
ZFAND6



zinc finger, AN1-type domain 6



chr16_+_1359138 0.314 ENST00000325437.5
UBE2I
ubiquitin-conjugating enzyme E2I
chrX_+_55744166 0.312 ENST00000374941.4
ENST00000414239.1
RRAGB

Ras-related GTP binding B

chr11_-_68039364 0.308 ENST00000533310.1
ENST00000304271.6
ENST00000527280.1
C11orf24


chromosome 11 open reading frame 24


chrX_+_55744228 0.306 ENST00000262850.7
RRAGB
Ras-related GTP binding B
chr4_+_159593271 0.302 ENST00000512251.1
ENST00000511912.1
ETFDH

electron-transferring-flavoprotein dehydrogenase

chr14_+_102027688 0.299 ENST00000510508.4
ENST00000359323.3
DIO3

deiodinase, iodothyronine, type III

chr1_-_48937821 0.298 ENST00000396199.3
SPATA6
spermatogenesis associated 6
chr15_-_34659349 0.292 ENST00000314891.6
LPCAT4
lysophosphatidylcholine acyltransferase 4
chr12_+_16035307 0.289 ENST00000538352.1
ENST00000025399.6
ENST00000419869.2
STRAP


serine/threonine kinase receptor associated protein


chr10_-_112678976 0.289 ENST00000448814.1
BBIP1
BBSome interacting protein 1
chrX_-_135338503 0.284 ENST00000370663.5
MAP7D3
MAP7 domain containing 3
chr12_+_110011571 0.283 ENST00000539696.1
ENST00000228510.3
ENST00000392727.3
MVK


mevalonate kinase


chr17_+_33914276 0.283 ENST00000592545.1
ENST00000538556.1
ENST00000312678.8
ENST00000589344.1
AP2B1



adaptor-related protein complex 2, beta 1 subunit



chr2_+_220283091 0.283 ENST00000373960.3
DES
desmin
chr1_-_43855479 0.283 ENST00000290663.6
ENST00000372457.4
MED8

mediator complex subunit 8

chr17_+_42427826 0.280 ENST00000586443.1
GRN
granulin
chr7_-_105752651 0.276 ENST00000470347.1
ENST00000455385.2
SYPL1

synaptophysin-like 1

chr10_-_112678692 0.271 ENST00000605742.1
BBIP1
BBSome interacting protein 1
chr1_-_48937838 0.270 ENST00000371847.3
SPATA6
spermatogenesis associated 6
chr19_+_16296191 0.266 ENST00000589852.1
ENST00000263384.7
ENST00000588367.1
ENST00000587351.1
FAM32A



family with sequence similarity 32, member A



chr1_+_215256467 0.265 ENST00000391894.2
ENST00000444842.2
KCNK2

potassium channel, subfamily K, member 2

chr2_+_192542850 0.262 ENST00000410026.2
NABP1
nucleic acid binding protein 1
chr19_-_46285646 0.260 ENST00000458663.2
DMPK
dystrophia myotonica-protein kinase
chr3_+_44596679 0.257 ENST00000426540.1
ENST00000431636.1
ENST00000341840.3
ENST00000273320.3
ZKSCAN7



zinc finger with KRAB and SCAN domains 7



chr19_-_14228541 0.256 ENST00000590853.1
ENST00000308677.4
PRKACA

protein kinase, cAMP-dependent, catalytic, alpha

chr11_-_33795893 0.255 ENST00000526785.1
ENST00000534136.1
ENST00000265651.3
ENST00000530401.1
ENST00000448981.2
FBXO3




F-box protein 3




chrX_-_153640420 0.254 ENST00000451865.1
ENST00000432135.1
ENST00000369809.1
ENST00000393638.1
ENST00000424626.1
ENST00000309585.5
DNASE1L1





deoxyribonuclease I-like 1





chr3_+_40428647 0.254 ENST00000301825.3
ENST00000439533.1
ENST00000456402.1
ENTPD3


ectonucleoside triphosphate diphosphohydrolase 3


chr9_-_88969303 0.250 ENST00000277141.6
ENST00000375963.3
ZCCHC6

zinc finger, CCHC domain containing 6

chr21_-_46707793 0.249 ENST00000331343.7
ENST00000349485.5
POFUT2

protein O-fucosyltransferase 2

chr17_+_33914460 0.249 ENST00000537622.2
AP2B1
adaptor-related protein complex 2, beta 1 subunit
chr3_-_118959733 0.247 ENST00000459778.1
ENST00000359213.3
B4GALT4

UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4

chr12_+_6644443 0.246 ENST00000396858.1
GAPDH
glyceraldehyde-3-phosphate dehydrogenase
chr22_-_19279201 0.245 ENST00000353891.5
ENST00000263200.10
ENST00000427926.1
ENST00000449918.1
CLTCL1



clathrin, heavy chain-like 1



chr9_-_88969339 0.244 ENST00000375960.2
ENST00000375961.2
ZCCHC6

zinc finger, CCHC domain containing 6

chr5_-_146781153 0.243 ENST00000520473.1
DPYSL3
dihydropyrimidinase-like 3
chr5_-_171433579 0.243 ENST00000265094.5
ENST00000393802.2
FBXW11

F-box and WD repeat domain containing 11

chr22_+_45072958 0.240 ENST00000403581.1
PRR5
proline rich 5 (renal)
chr10_+_105036909 0.240 ENST00000369849.4
INA
internexin neuronal intermediate filament protein, alpha
chr19_+_39390587 0.238 ENST00000572515.1
ENST00000392079.3
ENST00000575359.1
ENST00000313582.5
NFKBIB



nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta



chrX_+_101975643 0.232 ENST00000361229.4
BHLHB9
basic helix-loop-helix domain containing, class B, 9
chr1_+_3816936 0.232 ENST00000413332.1
ENST00000442673.1
ENST00000439488.1
RP13-15E13.1


long intergenic non-protein coding RNA 1134


chrX_+_101975619 0.227 ENST00000457056.1
BHLHB9
basic helix-loop-helix domain containing, class B, 9
chr1_-_48937682 0.225 ENST00000371843.3
SPATA6
spermatogenesis associated 6
chr4_-_186125077 0.223 ENST00000458385.2
ENST00000514798.1
ENST00000296775.6
KIAA1430


KIAA1430


chr4_-_2936514 0.222 ENST00000508221.1
ENST00000507555.1
ENST00000355443.4
MFSD10


major facilitator superfamily domain containing 10


chr10_-_44144292 0.221 ENST00000374433.2
ZNF32
zinc finger protein 32
chr17_+_7210898 0.219 ENST00000572815.1
EIF5A
eukaryotic translation initiation factor 5A
chr1_-_200379180 0.218 ENST00000294740.3
ZNF281
zinc finger protein 281
chr22_+_45072925 0.218 ENST00000006251.7
PRR5
proline rich 5 (renal)
chr15_-_63448973 0.218 ENST00000462430.1
RPS27L
ribosomal protein S27-like
chr1_+_145611010 0.217 ENST00000369291.5
RNF115
ring finger protein 115
chr3_-_127317047 0.215 ENST00000462228.1
ENST00000490643.1
TPRA1

transmembrane protein, adipocyte asscociated 1

chr10_-_112678904 0.212 ENST00000423273.1
ENST00000436562.1
ENST00000447005.1
ENST00000454061.1
BBIP1



BBSome interacting protein 1



chr3_+_133293278 0.212 ENST00000508481.1
ENST00000420115.2
ENST00000504867.1
ENST00000507408.1
ENST00000511392.1
ENST00000515421.1
CDV3





CDV3 homolog (mouse)





chr13_-_48575443 0.211 ENST00000378654.3
SUCLA2
succinate-CoA ligase, ADP-forming, beta subunit
chr3_-_52486841 0.202 ENST00000496590.1
TNNC1
troponin C type 1 (slow)
chr17_-_2304365 0.200 ENST00000575394.1
ENST00000174618.4
MNT

MAX network transcriptional repressor

chr5_+_150827143 0.196 ENST00000243389.3
ENST00000517945.1
ENST00000521925.1
SLC36A1


solute carrier family 36 (proton/amino acid symporter), member 1


chr14_-_45603657 0.195 ENST00000396062.3
FKBP3
FK506 binding protein 3, 25kDa
chr17_-_2207062 0.193 ENST00000263073.6
SMG6
SMG6 nonsense mediated mRNA decay factor
chr5_-_171433819 0.193 ENST00000296933.6
FBXW11
F-box and WD repeat domain containing 11
chr6_-_110500905 0.192 ENST00000392587.2
WASF1
WAS protein family, member 1
chrX_+_99899180 0.189 ENST00000373004.3
SRPX2
sushi-repeat containing protein, X-linked 2
chr1_+_109289279 0.179 ENST00000370008.3
STXBP3
syntaxin binding protein 3
chr13_-_48575401 0.178 ENST00000433022.1
ENST00000544100.1
SUCLA2

succinate-CoA ligase, ADP-forming, beta subunit

chr19_-_46285736 0.178 ENST00000291270.4
ENST00000447742.2
ENST00000354227.5
DMPK


dystrophia myotonica-protein kinase


chr10_-_44144152 0.177 ENST00000395797.1
ZNF32
zinc finger protein 32
chr11_+_65339820 0.172 ENST00000316409.2
ENST00000449319.2
ENST00000530349.1
FAM89B


family with sequence similarity 89, member B


chr16_+_8891670 0.172 ENST00000268261.4
ENST00000539622.1
ENST00000569958.1
ENST00000537352.1
PMM2



phosphomannomutase 2



chr17_+_4843303 0.171 ENST00000571816.1
RNF167
ring finger protein 167
chr17_-_2206801 0.171 ENST00000544865.1
SMG6
SMG6 nonsense mediated mRNA decay factor
chr4_-_178363581 0.166 ENST00000264595.2
AGA
aspartylglucosaminidase
chr6_-_74233480 0.165 ENST00000455918.1
EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr5_+_150639360 0.164 ENST00000523004.1
GM2A
GM2 ganglioside activator
chr13_+_53029564 0.163 ENST00000468284.1
ENST00000378034.3
ENST00000258607.5
ENST00000378037.5
CKAP2



cytoskeleton associated protein 2



chr19_+_58095501 0.162 ENST00000536878.2
ENST00000597850.1
ENST00000597219.1
ENST00000598689.1
ENST00000599456.1
ENST00000307468.4
ZIK1





zinc finger protein interacting with K protein 1





chr14_-_64194745 0.162 ENST00000247225.6
SGPP1
sphingosine-1-phosphate phosphatase 1
chr10_-_101380121 0.162 ENST00000370495.4
SLC25A28
solute carrier family 25 (mitochondrial iron transporter), member 28
chr6_+_132129151 0.161 ENST00000360971.2
ENPP1
ectonucleotide pyrophosphatase/phosphodiesterase 1
chr19_+_18682531 0.160 ENST00000596304.1
ENST00000430157.2
UBA52

ubiquitin A-52 residue ribosomal protein fusion product 1

chr1_-_43855444 0.159 ENST00000372455.4
MED8
mediator complex subunit 8
chr19_+_54694119 0.156 ENST00000456872.1
ENST00000302937.4
ENST00000429671.2
TSEN34


TSEN34 tRNA splicing endonuclease subunit


chrX_+_153524024 0.153 ENST00000369915.3
ENST00000217905.7
TKTL1

transketolase-like 1

chr17_+_7348658 0.152 ENST00000570557.1
ENST00000536404.2
ENST00000576360.1
CHRNB1


cholinergic receptor, nicotinic, beta 1 (muscle)


chr12_+_133613878 0.151 ENST00000392319.2
ENST00000543758.1
ZNF84

zinc finger protein 84

chr19_+_39390320 0.150 ENST00000576510.1
NFKBIB
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr19_+_18682661 0.150 ENST00000596273.1
ENST00000442744.2
ENST00000595683.1
ENST00000599256.1
ENST00000595158.1
ENST00000598780.1
UBA52





ubiquitin A-52 residue ribosomal protein fusion product 1





chr4_+_76439665 0.150 ENST00000508105.1
ENST00000311638.3
ENST00000380837.3
ENST00000507556.1
ENST00000504190.1
ENST00000507885.1
ENST00000502620.1
ENST00000514480.1
THAP6







THAP domain containing 6








Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.1 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
1.0 6.9 GO:2000111 positive regulation of macrophage apoptotic process(GO:2000111)
0.9 2.7 GO:0060340 pericardium morphogenesis(GO:0003344) optic cup formation involved in camera-type eye development(GO:0003408) diencephalon morphogenesis(GO:0048852) positive regulation of type I interferon-mediated signaling pathway(GO:0060340) lateral sprouting involved in mammary gland duct morphogenesis(GO:0060599)
0.8 2.4 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.4 1.7 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.3 1.0 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.3 0.9 GO:0034036 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.3 1.3 GO:0019471 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.2 0.9 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.2 1.2 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.2 1.1 GO:1901881 positive regulation of protein depolymerization(GO:1901881)
0.2 0.5 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891)
0.1 1.5 GO:0051014 actin filament severing(GO:0051014)
0.1 0.4 GO:0071639 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559) positive regulation of monocyte chemotactic protein-1 production(GO:0071639)
0.1 0.4 GO:0042511 positive regulation of tyrosine phosphorylation of Stat1 protein(GO:0042511) leukemia inhibitory factor signaling pathway(GO:0048861)
0.1 1.1 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1 0.4 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.1 2.0 GO:0032456 endocytic recycling(GO:0032456)
0.1 0.4 GO:0007403 glial cell fate determination(GO:0007403)
0.1 0.8 GO:0034616 response to laminar fluid shear stress(GO:0034616)
0.1 0.7 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.1 1.2 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.1 0.3 GO:0046495 nicotinamide riboside catabolic process(GO:0006738) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638)
0.1 0.7 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 0.8 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.1 0.4 GO:0006104 succinyl-CoA metabolic process(GO:0006104) uroporphyrinogen III biosynthetic process(GO:0006780)
0.1 2.4 GO:0045103 intermediate filament-based process(GO:0045103)
0.1 0.5 GO:0060242 contact inhibition(GO:0060242)
0.1 1.3 GO:0050872 white fat cell differentiation(GO:0050872)
0.1 0.3 GO:0071374 cellular response to parathyroid hormone stimulus(GO:0071374)
0.1 1.3 GO:0042749 regulation of circadian sleep/wake cycle(GO:0042749) regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.1 0.4 GO:0033145 positive regulation of intracellular steroid hormone receptor signaling pathway(GO:0033145)
0.1 0.1 GO:2000309 tumor necrosis factor (ligand) superfamily member 11 production(GO:0072535) regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000307) positive regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000309)
0.1 0.4 GO:0014819 regulation of skeletal muscle contraction(GO:0014819)
0.1 0.2 GO:1903115 regulation of muscle filament sliding(GO:0032971) regulation of actin filament-based movement(GO:1903115)
0.1 0.5 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 1.4 GO:0035115 embryonic forelimb morphogenesis(GO:0035115)
0.1 0.4 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 0.4 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.1 0.2 GO:0017014 protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.1 0.2 GO:0070527 platelet aggregation(GO:0070527)
0.1 0.2 GO:0006530 asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.1 0.2 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719)
0.1 0.5 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.1 0.5 GO:0021513 spinal cord dorsal/ventral patterning(GO:0021513)
0.0 0.1 GO:0031558 obsolete induction of apoptosis in response to chemical stimulus(GO:0031558) determination of dorsal/ventral asymmetry(GO:0048262) determination of dorsal identity(GO:0048263)
0.0 1.4 GO:0002040 sprouting angiogenesis(GO:0002040)
0.0 0.1 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
0.0 0.1 GO:0060363 cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.0 0.2 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.0 0.2 GO:0000394 RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394) tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.6 GO:0071230 positive regulation of TOR signaling(GO:0032008) cellular response to amino acid stimulus(GO:0071230)
0.0 0.2 GO:0006007 glucose catabolic process(GO:0006007)
0.0 0.2 GO:0001941 postsynaptic membrane organization(GO:0001941)
0.0 0.2 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.2 GO:0015904 tetracycline transport(GO:0015904)
0.0 0.5 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.7 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 0.2 GO:0043243 translational frameshifting(GO:0006452) positive regulation of protein complex disassembly(GO:0043243) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0 0.1 GO:0007285 primary spermatocyte growth(GO:0007285)
0.0 0.4 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.2 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.1 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 4.5 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 0.7 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.6 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.4 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.8 GO:0042384 cilium assembly(GO:0042384)
0.0 0.1 GO:0042518 negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.0 1.4 GO:0000910 cytokinesis(GO:0000910)
0.0 1.5 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.1 GO:0046487 glyoxylate metabolic process(GO:0046487)
0.0 0.1 GO:0045116 protein neddylation(GO:0045116)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:0016075 rRNA catabolic process(GO:0016075)
0.0 0.0 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.0 0.2 GO:0006004 fucose metabolic process(GO:0006004)
0.0 0.5 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) negative regulation of ERBB signaling pathway(GO:1901185)
0.0 2.9 GO:0006184 obsolete GTP catabolic process(GO:0006184)
0.0 0.3 GO:0001662 behavioral fear response(GO:0001662)
0.0 0.5 GO:1900181 negative regulation of protein import into nucleus(GO:0042308) negative regulation of protein localization to nucleus(GO:1900181) negative regulation of protein import(GO:1904590)
0.0 0.1 GO:0002281 macrophage activation involved in immune response(GO:0002281)
0.0 0.5 GO:0042594 response to starvation(GO:0042594)
0.0 0.2 GO:0006911 phagocytosis, engulfment(GO:0006911) membrane invagination(GO:0010324)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.4 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.2 1.2 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1 0.4 GO:0001650 fibrillar center(GO:0001650)
0.1 0.4 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.1 1.2 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1 1.0 GO:0005677 chromatin silencing complex(GO:0005677)
0.1 0.7 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.1 1.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 0.2 GO:0031091 platelet alpha granule(GO:0031091)
0.1 0.8 GO:0034464 BBSome(GO:0034464)
0.1 0.7 GO:0005916 fascia adherens(GO:0005916)
0.1 0.4 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.1 0.6 GO:0031430 M band(GO:0031430)
0.0 0.1 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.2 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.0 0.2 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.6 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 3.4 GO:0005882 intermediate filament(GO:0005882)
0.0 1.9 GO:0030175 filopodium(GO:0030175)
0.0 1.4 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.2 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.4 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.4 GO:0005606 laminin-1 complex(GO:0005606)
0.0 0.7 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.8 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.4 GO:0046930 pore complex(GO:0046930)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.9 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.5 GO:0005811 lipid particle(GO:0005811)
0.0 0.4 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.4 GO:0016592 mediator complex(GO:0016592)
0.0 1.1 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 3.7 GO:0016604 nuclear body(GO:0016604)
0.0 0.9 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.2 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.0 5.8 GO:0009986 cell surface(GO:0009986)
0.0 0.3 GO:0031594 neuromuscular junction(GO:0031594)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 6.9 GO:0055105 ubiquitin-protein transferase inhibitor activity(GO:0055105)
0.4 1.1 GO:0019215 intermediate filament binding(GO:0019215)
0.4 1.4 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.3 2.7 GO:0005110 frizzled-2 binding(GO:0005110)
0.3 0.9 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.3 1.2 GO:0008160 protein tyrosine phosphatase activator activity(GO:0008160) protein phosphatase activator activity(GO:0072542)
0.3 1.3 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.3 1.0 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.2 0.9 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.2 0.7 GO:0048039 ubiquinone binding(GO:0048039)
0.1 0.4 GO:0019981 interleukin-6 receptor activity(GO:0004915) oncostatin-M receptor activity(GO:0004924) ciliary neurotrophic factor receptor binding(GO:0005127) interleukin-6 binding(GO:0019981) interleukin-17 receptor activity(GO:0030368)
0.1 0.7 GO:0017096 acetylserotonin O-methyltransferase activity(GO:0017096)
0.1 0.5 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.1 0.3 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.1 1.4 GO:0019841 retinol binding(GO:0019841)
0.1 0.4 GO:0043398 HLH domain binding(GO:0043398)
0.1 1.5 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.1 0.4 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
0.1 0.4 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328) N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.1 1.6 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 0.4 GO:0051434 BH3 domain binding(GO:0051434)
0.1 0.4 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.1 0.5 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.1 1.6 GO:0043498 obsolete cell surface binding(GO:0043498)
0.1 0.4 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 0.5 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 0.2 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1 0.7 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 0.8 GO:0004065 arylsulfatase activity(GO:0004065)
0.1 0.2 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.1 0.2 GO:0004802 transketolase activity(GO:0004802)
0.0 0.3 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.2 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 0.7 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.3 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.4 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 1.2 GO:0050699 WW domain binding(GO:0050699)
0.0 0.4 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.5 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0 0.1 GO:0004607 phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.0 0.2 GO:0008493 tetracycline transporter activity(GO:0008493)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.2 GO:0004528 phosphodiesterase I activity(GO:0004528) 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0 0.1 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.5 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.2 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 5.4 GO:0005125 cytokine activity(GO:0005125)
0.0 0.2 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0 0.2 GO:0031013 troponin I binding(GO:0031013)
0.0 2.7 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 1.4 GO:0051287 NAD binding(GO:0051287)
0.0 1.1 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.2 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.3 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 2.1 GO:0031072 heat shock protein binding(GO:0031072)
0.0 0.1 GO:0005112 Notch binding(GO:0005112)
0.0 0.3 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.6 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.1 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.2 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.4 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.4 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.1 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.0 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 4.4 GO:0003924 GTPase activity(GO:0003924)
0.0 0.2 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 0.3 GO:0043621 protein self-association(GO:0043621)
0.0 0.1 GO:0033691 sialic acid binding(GO:0033691)
0.0 1.4 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0016616)
0.0 0.2 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.2 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.2 GO:0042166 acetylcholine binding(GO:0042166)
0.0 1.2 GO:0001664 G-protein coupled receptor binding(GO:0001664)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 6.9 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.6 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.3 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton