Motif ID: RARB
Z-value: 1.559
Transcription factors associated with RARB:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| RARB | ENSG00000077092.14 | RARB |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 2.2 | GO:0071379 | cellular response to prostaglandin stimulus(GO:0071379) |
| 0.4 | 2.4 | GO:0009450 | gamma-aminobutyric acid catabolic process(GO:0009450) |
| 0.3 | 1.1 | GO:0010903 | negative regulation of cytokine secretion involved in immune response(GO:0002740) negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903) |
| 0.2 | 1.4 | GO:0006772 | thiamine metabolic process(GO:0006772) |
| 0.2 | 0.8 | GO:0070527 | integrin activation(GO:0033622) regulation of integrin activation(GO:0033623) positive regulation of integrin activation(GO:0033625) platelet aggregation(GO:0070527) |
| 0.2 | 0.8 | GO:0006408 | snRNA export from nucleus(GO:0006408) snRNA transport(GO:0051030) |
| 0.2 | 0.6 | GO:0009162 | deoxyribonucleoside monophosphate metabolic process(GO:0009162) pyrimidine deoxyribonucleoside monophosphate metabolic process(GO:0009176) transformation of host cell by virus(GO:0019087) dUMP metabolic process(GO:0046078) intestinal epithelial cell maturation(GO:0060574) intestinal epithelial cell development(GO:0060576) |
| 0.2 | 0.5 | GO:0046600 | negative regulation of centriole replication(GO:0046600) |
| 0.1 | 0.9 | GO:0032460 | negative regulation of protein oligomerization(GO:0032460) negative regulation of protein homooligomerization(GO:0032463) |
| 0.1 | 0.8 | GO:0006658 | phosphatidylserine metabolic process(GO:0006658) |
| 0.1 | 0.4 | GO:0045198 | establishment of epithelial cell apical/basal polarity(GO:0045198) |
| 0.1 | 0.6 | GO:0032497 | detection of lipopolysaccharide(GO:0032497) |
| 0.1 | 0.8 | GO:0030277 | epithelial structure maintenance(GO:0010669) maintenance of gastrointestinal epithelium(GO:0030277) |
| 0.1 | 0.5 | GO:0060236 | regulation of mitotic spindle organization(GO:0060236) |
| 0.1 | 3.6 | GO:0050853 | B cell receptor signaling pathway(GO:0050853) |
| 0.1 | 0.6 | GO:0051387 | negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387) |
| 0.1 | 0.9 | GO:0051290 | protein heterotetramerization(GO:0051290) |
| 0.1 | 0.3 | GO:0046984 | regulation of hemoglobin biosynthetic process(GO:0046984) |
| 0.1 | 1.2 | GO:0046827 | positive regulation of protein export from nucleus(GO:0046827) |
| 0.1 | 1.3 | GO:0033169 | histone H3-K9 demethylation(GO:0033169) |
| 0.1 | 0.7 | GO:0006069 | ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069) |
| 0.1 | 1.1 | GO:0048207 | vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114) |
| 0.1 | 0.2 | GO:0046599 | regulation of centriole replication(GO:0046599) |
| 0.1 | 0.6 | GO:1902591 | vesicle coating(GO:0006901) single-organism membrane budding(GO:1902591) |
| 0.1 | 0.2 | GO:0045085 | negative regulation of interleukin-2 biosynthetic process(GO:0045085) |
| 0.1 | 0.4 | GO:0042984 | amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984) |
| 0.1 | 0.9 | GO:0050930 | induction of positive chemotaxis(GO:0050930) |
| 0.0 | 0.1 | GO:0016926 | protein desumoylation(GO:0016926) |
| 0.0 | 0.6 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 0.0 | 0.2 | GO:0015811 | sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811) |
| 0.0 | 0.3 | GO:0035335 | peptidyl-tyrosine dephosphorylation(GO:0035335) |
| 0.0 | 0.6 | GO:0006098 | pentose-phosphate shunt(GO:0006098) glyceraldehyde-3-phosphate metabolic process(GO:0019682) |
| 0.0 | 0.5 | GO:0016558 | protein import into peroxisome matrix(GO:0016558) |
| 0.0 | 0.2 | GO:0031282 | regulation of guanylate cyclase activity(GO:0031282) |
| 0.0 | 0.1 | GO:0070050 | neuron cellular homeostasis(GO:0070050) |
| 0.0 | 0.6 | GO:0031055 | DNA replication-independent nucleosome assembly(GO:0006336) chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) DNA replication-independent nucleosome organization(GO:0034724) CENP-A containing chromatin organization(GO:0061641) |
| 0.0 | 0.1 | GO:0009992 | cellular water homeostasis(GO:0009992) |
| 0.0 | 0.1 | GO:0045163 | clustering of voltage-gated potassium channels(GO:0045163) |
| 0.0 | 0.8 | GO:0006271 | DNA replication initiation(GO:0006270) DNA strand elongation involved in DNA replication(GO:0006271) |
| 0.0 | 0.4 | GO:0008635 | activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635) |
| 0.0 | 0.3 | GO:0006198 | cAMP catabolic process(GO:0006198) |
| 0.0 | 0.1 | GO:0009822 | alkaloid catabolic process(GO:0009822) |
| 0.0 | 1.0 | GO:0043038 | tRNA aminoacylation for protein translation(GO:0006418) amino acid activation(GO:0043038) tRNA aminoacylation(GO:0043039) |
| 0.0 | 0.6 | GO:0006888 | ER to Golgi vesicle-mediated transport(GO:0006888) |
| 0.0 | 0.6 | GO:0000060 | protein import into nucleus, translocation(GO:0000060) |
| 0.0 | 0.3 | GO:0046907 | intracellular transport(GO:0046907) |
| 0.0 | 0.0 | GO:0014831 | intestine smooth muscle contraction(GO:0014827) gastro-intestinal system smooth muscle contraction(GO:0014831) |
| 0.0 | 0.2 | GO:0045494 | photoreceptor cell maintenance(GO:0045494) |
| 0.0 | 1.8 | GO:0009636 | response to toxic substance(GO:0009636) |
| 0.0 | 0.1 | GO:0055091 | phospholipid homeostasis(GO:0055091) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 2.2 | GO:0031904 | endosome lumen(GO:0031904) |
| 0.2 | 0.6 | GO:0070288 | intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288) |
| 0.1 | 0.4 | GO:0005608 | laminin-3 complex(GO:0005608) |
| 0.1 | 1.4 | GO:0031254 | uropod(GO:0001931) cell trailing edge(GO:0031254) |
| 0.1 | 0.6 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
| 0.1 | 0.5 | GO:0031436 | BRCA1-BARD1 complex(GO:0031436) |
| 0.1 | 2.0 | GO:0034366 | spherical high-density lipoprotein particle(GO:0034366) |
| 0.1 | 1.2 | GO:0042555 | MCM complex(GO:0042555) |
| 0.1 | 0.4 | GO:0000137 | Golgi cis cisterna(GO:0000137) |
| 0.1 | 0.7 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
| 0.1 | 0.6 | GO:0030126 | COPI vesicle coat(GO:0030126) |
| 0.1 | 1.7 | GO:0030134 | ER to Golgi transport vesicle(GO:0030134) |
| 0.0 | 0.3 | GO:0032311 | angiogenin-PRI complex(GO:0032311) |
| 0.0 | 0.5 | GO:0035253 | ciliary rootlet(GO:0035253) |
| 0.0 | 0.2 | GO:0005658 | alpha DNA polymerase:primase complex(GO:0005658) |
| 0.0 | 0.2 | GO:0000125 | PCAF complex(GO:0000125) |
| 0.0 | 1.2 | GO:0005884 | actin filament(GO:0005884) |
| 0.0 | 0.2 | GO:0030897 | HOPS complex(GO:0030897) |
| 0.0 | 1.2 | GO:0008287 | protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293) |
| 0.0 | 3.6 | GO:0098857 | membrane raft(GO:0045121) membrane microdomain(GO:0098857) |
| 0.0 | 0.2 | GO:0001917 | photoreceptor inner segment(GO:0001917) |
| 0.0 | 0.1 | GO:0070531 | BRCA1-A complex(GO:0070531) |
| 0.0 | 0.6 | GO:0005814 | centriole(GO:0005814) |
| 0.0 | 6.4 | GO:0005625 | obsolete soluble fraction(GO:0005625) |
| 0.0 | 0.1 | GO:0046581 | intercellular canaliculus(GO:0046581) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 1.0 | GO:0004917 | interleukin-4 receptor activity(GO:0004913) interleukin-7 receptor activity(GO:0004917) interleukin-2 binding(GO:0019976) |
| 0.3 | 1.1 | GO:0034190 | apolipoprotein receptor binding(GO:0034190) high-density lipoprotein particle receptor binding(GO:0070653) |
| 0.3 | 0.8 | GO:0008970 | phosphatidylcholine 1-acylhydrolase activity(GO:0008970) |
| 0.2 | 1.4 | GO:0016778 | diphosphotransferase activity(GO:0016778) |
| 0.2 | 2.3 | GO:0017127 | cholesterol transporter activity(GO:0017127) |
| 0.2 | 0.5 | GO:0070260 | 5'-tyrosyl-DNA phosphodiesterase activity(GO:0070260) |
| 0.1 | 1.3 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) |
| 0.1 | 0.3 | GO:0004694 | eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694) |
| 0.1 | 3.7 | GO:0042169 | SH2 domain binding(GO:0042169) |
| 0.1 | 0.9 | GO:0004332 | fructose-bisphosphate aldolase activity(GO:0004332) |
| 0.1 | 2.2 | GO:0004623 | phospholipase A2 activity(GO:0004623) |
| 0.1 | 0.2 | GO:0042289 | MHC class II protein binding(GO:0042289) |
| 0.1 | 0.8 | GO:0047760 | butyrate-CoA ligase activity(GO:0047760) |
| 0.1 | 0.8 | GO:0015643 | toxic substance binding(GO:0015643) |
| 0.1 | 1.2 | GO:0005522 | profilin binding(GO:0005522) |
| 0.1 | 0.3 | GO:0008428 | ribonuclease inhibitor activity(GO:0008428) |
| 0.1 | 0.8 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
| 0.1 | 0.7 | GO:0004022 | alcohol dehydrogenase (NAD) activity(GO:0004022) |
| 0.1 | 0.6 | GO:0001875 | lipopolysaccharide receptor activity(GO:0001875) |
| 0.1 | 2.4 | GO:0016620 | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620) |
| 0.1 | 0.9 | GO:0051787 | misfolded protein binding(GO:0051787) |
| 0.1 | 0.6 | GO:0003688 | DNA replication origin binding(GO:0003688) |
| 0.1 | 0.2 | GO:0015361 | low-affinity sodium:dicarboxylate symporter activity(GO:0015361) |
| 0.0 | 0.1 | GO:0016929 | SUMO-specific protease activity(GO:0016929) |
| 0.0 | 0.6 | GO:0008199 | ferric iron binding(GO:0008199) |
| 0.0 | 2.3 | GO:0004180 | carboxypeptidase activity(GO:0004180) |
| 0.0 | 0.5 | GO:0016861 | intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861) |
| 0.0 | 0.2 | GO:0015184 | L-cystine transmembrane transporter activity(GO:0015184) |
| 0.0 | 0.6 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
| 0.0 | 0.4 | GO:0043208 | glycosphingolipid binding(GO:0043208) |
| 0.0 | 0.6 | GO:0005537 | mannose binding(GO:0005537) |
| 0.0 | 0.2 | GO:0008048 | calcium sensitive guanylate cyclase activator activity(GO:0008048) |
| 0.0 | 0.6 | GO:0005542 | folic acid binding(GO:0005542) |
| 0.0 | 0.3 | GO:0031419 | cobalamin binding(GO:0031419) |
| 0.0 | 0.2 | GO:0008020 | G-protein coupled photoreceptor activity(GO:0008020) |
| 0.0 | 0.1 | GO:0005250 | A-type (transient outward) potassium channel activity(GO:0005250) |
| 0.0 | 0.6 | GO:0017134 | fibroblast growth factor binding(GO:0017134) |
| 0.0 | 0.2 | GO:0008607 | phosphorylase kinase regulator activity(GO:0008607) |
| 0.0 | 1.1 | GO:0016875 | aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876) |
| 0.0 | 1.2 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
| 0.0 | 0.1 | GO:0070643 | vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643) |
| 0.0 | 0.1 | GO:0015562 | efflux transmembrane transporter activity(GO:0015562) |
| 0.0 | 0.7 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
| 0.0 | 1.3 | GO:0005178 | integrin binding(GO:0005178) |
| 0.0 | 0.1 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
| 0.0 | 0.1 | GO:0015185 | gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.0 | ST_INTERLEUKIN_4_PATHWAY | Interleukin 4 (IL-4) Pathway |
| 0.0 | 0.5 | SA_CASPASE_CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
