Motif ID: RARG

Z-value: 2.507


Transcription factors associated with RARG:

Gene SymbolEntrez IDGene Name
RARG ENSG00000172819.12 RARG



Activity profile for motif RARG.

activity profile for motif RARG


Sorted Z-values histogram for motif RARG

Sorted Z-values for motif RARG



Network of associatons between targets according to the STRING database.



First level regulatory network of RARG

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_156647189 4.275 ENST00000368223.3
NES
nestin
chr15_+_33010175 4.207 ENST00000300177.4
ENST00000560677.1
ENST00000560830.1
GREM1


gremlin 1, DAN family BMP antagonist


chr7_-_107642348 3.724 ENST00000393561.1
LAMB1
laminin, beta 1
chr11_+_117073850 3.618 ENST00000529622.1
TAGLN
transgelin
chr8_-_108510224 3.417 ENST00000517746.1
ENST00000297450.3
ANGPT1

angiopoietin 1

chr9_-_130637244 3.334 ENST00000373156.1
AK1
adenylate kinase 1
chr12_-_91576429 3.256 ENST00000552145.1
ENST00000546745.1
DCN

decorin

chr11_-_111784005 2.713 ENST00000527899.1
CRYAB
crystallin, alpha B
chr1_+_196621002 2.661 ENST00000367429.4
ENST00000439155.2
CFH

complement factor H

chr8_+_70404996 2.655 ENST00000402687.4
ENST00000419716.3
SULF1

sulfatase 1

chr2_-_190044480 2.450 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr8_-_18666360 2.394 ENST00000286485.8
PSD3
pleckstrin and Sec7 domain containing 3
chr7_-_16685422 2.304 ENST00000306999.2
ANKMY2
ankyrin repeat and MYND domain containing 2
chr11_+_66624527 2.298 ENST00000393952.3
LRFN4
leucine rich repeat and fibronectin type III domain containing 4
chr1_+_196621156 2.278 ENST00000359637.2
CFH
complement factor H
chr13_+_102142296 2.271 ENST00000376162.3
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr2_+_69240415 2.233 ENST00000409829.3
ANTXR1
anthrax toxin receptor 1
chr11_-_111783595 2.217 ENST00000528628.1
CRYAB
crystallin, alpha B
chr11_+_114166536 2.188 ENST00000299964.3
NNMT
nicotinamide N-methyltransferase
chrX_+_135230712 2.177 ENST00000535737.1
FHL1
four and a half LIM domains 1
chr11_+_46402297 2.173 ENST00000405308.2
MDK
midkine (neurite growth-promoting factor 2)
chr9_-_35691017 2.169 ENST00000378292.3
TPM2
tropomyosin 2 (beta)
chr6_+_143999072 2.127 ENST00000440869.2
ENST00000367582.3
ENST00000451827.2
PHACTR2


phosphatase and actin regulator 2


chr11_-_5271122 2.069 ENST00000330597.3
HBG1
hemoglobin, gamma A
chr15_+_96876340 2.052 ENST00000453270.2
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr19_-_46974741 2.028 ENST00000313683.10
ENST00000602246.1
PNMAL1

paraneoplastic Ma antigen family-like 1

chr19_-_46974664 2.021 ENST00000438932.2
PNMAL1
paraneoplastic Ma antigen family-like 1
chr13_-_110959478 1.996 ENST00000543140.1
ENST00000375820.4
COL4A1

collagen, type IV, alpha 1

chr12_+_13349650 1.985 ENST00000256951.5
ENST00000431267.2
ENST00000542474.1
ENST00000544053.1
EMP1



epithelial membrane protein 1



chr12_+_93963590 1.983 ENST00000340600.2
SOCS2
suppressor of cytokine signaling 2
chr1_-_103574024 1.976 ENST00000512756.1
ENST00000370096.3
ENST00000358392.2
ENST00000353414.4
COL11A1



collagen, type XI, alpha 1



chr2_+_69240302 1.967 ENST00000303714.4
ANTXR1
anthrax toxin receptor 1
chr19_-_11308190 1.955 ENST00000586659.1
ENST00000592903.1
ENST00000589359.1
ENST00000588724.1
ENST00000432929.2
KANK2




KN motif and ankyrin repeat domains 2




chr15_+_96875657 1.952 ENST00000559679.1
ENST00000394171.2
NR2F2

nuclear receptor subfamily 2, group F, member 2

chr15_+_39873268 1.909 ENST00000397591.2
ENST00000260356.5
THBS1

thrombospondin 1

chr9_+_139873264 1.892 ENST00000446677.1
PTGDS
prostaglandin D2 synthase 21kDa (brain)
chr1_-_203144941 1.875 ENST00000255416.4
MYBPH
myosin binding protein H
chr12_-_21810726 1.855 ENST00000396076.1
LDHB
lactate dehydrogenase B
chr11_-_35547572 1.822 ENST00000378880.2
PAMR1
peptidase domain containing associated with muscle regeneration 1
chr10_+_17271266 1.808 ENST00000224237.5
VIM
vimentin
chr10_-_62761188 1.802 ENST00000357917.4
RHOBTB1
Rho-related BTB domain containing 1
chr10_+_17272608 1.791 ENST00000421459.2
VIM
vimentin
chrX_-_151938171 1.782 ENST00000393902.3
ENST00000417212.1
ENST00000370278.3
MAGEA3


melanoma antigen family A, 3


chr1_-_144994909 1.771 ENST00000369347.4
ENST00000369354.3
PDE4DIP

phosphodiesterase 4D interacting protein

chr3_+_45067659 1.757 ENST00000296130.4
CLEC3B
C-type lectin domain family 3, member B
chr11_+_46402744 1.756 ENST00000533952.1
MDK
midkine (neurite growth-promoting factor 2)
chr11_-_111783919 1.752 ENST00000531198.1
ENST00000533879.1
CRYAB

crystallin, alpha B

chr7_+_116165754 1.747 ENST00000405348.1
CAV1
caveolin 1, caveolae protein, 22kDa
chr8_-_93115445 1.723 ENST00000523629.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr10_-_33625154 1.717 ENST00000265371.4
NRP1
neuropilin 1
chr2_+_69240511 1.714 ENST00000409349.3
ANTXR1
anthrax toxin receptor 1
chr9_+_36036430 1.713 ENST00000377966.3
RECK
reversion-inducing-cysteine-rich protein with kazal motifs
chr8_-_23261589 1.708 ENST00000524168.1
ENST00000523833.2
ENST00000519243.1
ENST00000389131.3
LOXL2



lysyl oxidase-like 2



chr1_+_165600436 1.669 ENST00000367888.4
ENST00000367885.1
ENST00000367884.2
MGST3


microsomal glutathione S-transferase 3


chr7_+_128399002 1.661 ENST00000493278.1
CALU
calumenin
chr12_-_91576561 1.657 ENST00000547568.2
ENST00000552962.1
DCN

decorin

chr11_+_46402583 1.623 ENST00000359803.3
MDK
midkine (neurite growth-promoting factor 2)
chr6_-_2971429 1.616 ENST00000380529.1
SERPINB6
serpin peptidase inhibitor, clade B (ovalbumin), member 6
chr7_-_131241361 1.615 ENST00000378555.3
ENST00000322985.9
ENST00000541194.1
ENST00000537928.1
PODXL



podocalyxin-like



chr22_-_36236623 1.609 ENST00000405409.2
RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr2_-_238322800 1.594 ENST00000392004.3
ENST00000433762.1
ENST00000347401.3
ENST00000353578.4
ENST00000346358.4
ENST00000392003.2
COL6A3





collagen, type VI, alpha 3





chr2_-_238322770 1.574 ENST00000472056.1
COL6A3
collagen, type VI, alpha 3
chr2_-_158732340 1.574 ENST00000539637.1
ENST00000413751.1
ENST00000434821.1
ENST00000424669.1
ACVR1



activin A receptor, type I



chr5_+_34656331 1.552 ENST00000265109.3
RAI14
retinoic acid induced 14
chr12_+_119616447 1.552 ENST00000281938.2
HSPB8
heat shock 22kDa protein 8
chr1_-_17380630 1.549 ENST00000375499.3
SDHB
succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
chr11_-_64013663 1.545 ENST00000392210.2
PPP1R14B
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr7_+_79764104 1.527 ENST00000351004.3
GNAI1
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chr14_-_105420241 1.521 ENST00000557457.1
AHNAK2
AHNAK nucleoprotein 2
chr3_+_159557637 1.505 ENST00000445224.2
SCHIP1
schwannomin interacting protein 1
chr14_-_21492251 1.505 ENST00000554398.1
NDRG2
NDRG family member 2
chr10_-_44070016 1.502 ENST00000374446.2
ENST00000426961.1
ENST00000535642.1
ZNF239


zinc finger protein 239


chr19_-_43702231 1.497 ENST00000597374.1
ENST00000599371.1
PSG4

pregnancy specific beta-1-glycoprotein 4

chr3_-_168865522 1.487 ENST00000464456.1
MECOM
MDS1 and EVI1 complex locus
chr1_-_79472365 1.482 ENST00000370742.3
ELTD1
EGF, latrophilin and seven transmembrane domain containing 1
chr12_-_91573132 1.470 ENST00000550563.1
ENST00000546370.1
DCN

decorin

chr12_-_91576750 1.467 ENST00000228329.5
ENST00000303320.3
ENST00000052754.5
DCN


decorin


chr1_+_150480576 1.444 ENST00000346569.6
ECM1
extracellular matrix protein 1
chr12_-_56106060 1.426 ENST00000452168.2
ITGA7
integrin, alpha 7
chr14_-_21492113 1.393 ENST00000554094.1
NDRG2
NDRG family member 2
chr12_-_91573249 1.376 ENST00000550099.1
ENST00000546391.1
ENST00000551354.1
DCN


decorin


chr11_+_46402482 1.374 ENST00000441869.1
MDK
midkine (neurite growth-promoting factor 2)
chr8_+_98900132 1.368 ENST00000520016.1
MATN2
matrilin 2
chr2_-_86790593 1.356 ENST00000263856.4
ENST00000409225.2
CHMP3

charged multivesicular body protein 3

chrX_+_99899180 1.348 ENST00000373004.3
SRPX2
sushi-repeat containing protein, X-linked 2
chr3_-_46000064 1.332 ENST00000433878.1
FYCO1
FYVE and coiled-coil domain containing 1
chr14_+_61447927 1.319 ENST00000451406.1
SLC38A6
solute carrier family 38, member 6
chr11_-_35547151 1.313 ENST00000378878.3
ENST00000529303.1
ENST00000278360.3
PAMR1


peptidase domain containing associated with muscle regeneration 1


chr22_+_29702996 1.310 ENST00000406549.3
ENST00000360113.2
ENST00000341313.6
ENST00000403764.1
ENST00000471961.1
ENST00000407854.1
GAS2L1





growth arrest-specific 2 like 1





chr2_-_192711968 1.308 ENST00000304141.4
SDPR
serum deprivation response
chr9_-_35685452 1.301 ENST00000607559.1
TPM2
tropomyosin 2 (beta)
chr19_+_45394477 1.262 ENST00000252487.5
ENST00000405636.2
ENST00000592434.1
ENST00000426677.2
ENST00000589649.1
TOMM40




translocase of outer mitochondrial membrane 40 homolog (yeast)




chr1_-_17304771 1.260 ENST00000375534.3
MFAP2
microfibrillar-associated protein 2
chr1_+_163039143 1.246 ENST00000531057.1
ENST00000527809.1
ENST00000367908.4
RGS4


regulator of G-protein signaling 4


chr12_-_54689532 1.237 ENST00000540264.2
ENST00000312156.4
NFE2

nuclear factor, erythroid 2

chr1_-_154946825 1.233 ENST00000368453.4
ENST00000368450.1
ENST00000366442.2
SHC1


SHC (Src homology 2 domain containing) transforming protein 1


chr9_+_139874683 1.233 ENST00000444903.1
PTGDS
prostaglandin D2 synthase 21kDa (brain)
chrX_+_64887512 1.226 ENST00000360270.5
MSN
moesin
chr10_+_54074033 1.216 ENST00000373970.3
DKK1
dickkopf WNT signaling pathway inhibitor 1
chr1_+_223889285 1.206 ENST00000433674.2
CAPN2
calpain 2, (m/II) large subunit
chr19_-_43690674 1.201 ENST00000342951.6
ENST00000366175.3
PSG5

pregnancy specific beta-1-glycoprotein 5

chr18_-_21891460 1.195 ENST00000357041.4
OSBPL1A
oxysterol binding protein-like 1A
chr3_+_69985734 1.185 ENST00000314557.6
ENST00000394351.3
MITF

microphthalmia-associated transcription factor

chr14_+_61447832 1.165 ENST00000354886.2
ENST00000267488.4
SLC38A6

solute carrier family 38, member 6

chr1_-_85156216 1.164 ENST00000342203.3
ENST00000370612.4
SSX2IP

synovial sarcoma, X breakpoint 2 interacting protein

chr4_-_111119804 1.163 ENST00000394607.3
ENST00000302274.3
ELOVL6

ELOVL fatty acid elongase 6

chr22_-_36220420 1.162 ENST00000473487.2
RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr1_-_144994840 1.161 ENST00000369351.3
ENST00000369349.3
PDE4DIP

phosphodiesterase 4D interacting protein

chrX_+_117861535 1.150 ENST00000371666.3
ENST00000371642.1
IL13RA1

interleukin 13 receptor, alpha 1

chr1_+_160097462 1.147 ENST00000447527.1
ATP1A2
ATPase, Na+/K+ transporting, alpha 2 polypeptide
chr1_-_159894319 1.140 ENST00000320307.4
TAGLN2
transgelin 2
chr2_-_161350305 1.126 ENST00000348849.3
RBMS1
RNA binding motif, single stranded interacting protein 1
chr20_+_53092123 1.126 ENST00000262593.5
DOK5
docking protein 5
chr17_+_1665253 1.117 ENST00000254722.4
SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr4_-_16900217 1.108 ENST00000441778.2
LDB2
LIM domain binding 2
chr16_+_222846 1.078 ENST00000251595.6
ENST00000397806.1
HBA2

hemoglobin, alpha 2

chr19_-_43690642 1.078 ENST00000407356.1
ENST00000407568.1
ENST00000404580.1
ENST00000599812.1
PSG5



pregnancy specific beta-1-glycoprotein 5



chr4_+_169842707 1.076 ENST00000503290.1
PALLD
palladin, cytoskeletal associated protein
chrX_+_52780318 1.073 ENST00000375515.3
ENST00000276049.6
SSX2B

synovial sarcoma, X breakpoint 2B

chr4_-_16900410 1.072 ENST00000304523.5
LDB2
LIM domain binding 2
chr4_-_16900184 1.071 ENST00000515064.1
LDB2
LIM domain binding 2
chr4_-_111563076 1.070 ENST00000354925.2
ENST00000511990.1
PITX2

paired-like homeodomain 2

chr4_-_16900242 1.068 ENST00000502640.1
ENST00000506732.1
LDB2

LIM domain binding 2

chr10_+_75757863 1.063 ENST00000372755.3
ENST00000211998.4
ENST00000417648.2
VCL


vinculin


chr2_-_211179883 1.063 ENST00000352451.3
MYL1
myosin, light chain 1, alkali; skeletal, fast
chr17_+_60704762 1.061 ENST00000303375.5
MRC2
mannose receptor, C type 2
chr12_-_6665200 1.061 ENST00000336604.4
ENST00000396840.2
ENST00000356896.4
IFFO1


intermediate filament family orphan 1


chr2_+_10560147 1.061 ENST00000422133.1
HPCAL1
hippocalcin-like 1
chr21_+_42539701 1.059 ENST00000330333.6
ENST00000328735.6
ENST00000347667.5
BACE2


beta-site APP-cleaving enzyme 2


chr12_+_6494285 1.055 ENST00000541102.1
LTBR
lymphotoxin beta receptor (TNFR superfamily, member 3)
chrX_-_21776281 1.054 ENST00000379494.3
SMPX
small muscle protein, X-linked
chr9_+_120466650 1.054 ENST00000355622.6
TLR4
toll-like receptor 4
chr3_+_183894566 1.041 ENST00000439647.1
AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr5_+_170288856 1.037 ENST00000523189.1
RANBP17
RAN binding protein 17
chr11_-_407103 1.036 ENST00000526395.1
SIGIRR
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
chrX_-_48931648 1.028 ENST00000376386.3
ENST00000376390.4
PRAF2

PRA1 domain family, member 2

chr4_+_20255123 1.023 ENST00000504154.1
ENST00000273739.5
SLIT2

slit homolog 2 (Drosophila)

chrX_+_48114752 1.012 ENST00000376919.3
SSX1
synovial sarcoma, X breakpoint 1
chr6_-_112575912 1.010 ENST00000522006.1
ENST00000230538.7
ENST00000519932.1
LAMA4


laminin, alpha 4


chr4_-_7941596 1.006 ENST00000420658.1
ENST00000358461.2
AFAP1

actin filament associated protein 1

chr17_-_53809473 1.001 ENST00000575734.1
TMEM100
transmembrane protein 100
chr2_+_109237717 0.998 ENST00000409441.1
LIMS1
LIM and senescent cell antigen-like domains 1
chr11_-_86666427 0.985 ENST00000531380.1
FZD4
frizzled family receptor 4
chr2_+_223916862 0.982 ENST00000604125.1
KCNE4
potassium voltage-gated channel, Isk-related family, member 4
chr3_-_38691119 0.980 ENST00000333535.4
ENST00000413689.1
ENST00000443581.1
ENST00000425664.1
ENST00000451551.2
SCN5A




sodium channel, voltage-gated, type V, alpha subunit




chr17_+_1665345 0.976 ENST00000576406.1
ENST00000571149.1
SERPINF1

serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1

chr11_-_75017734 0.974 ENST00000532525.1
ARRB1
arrestin, beta 1
chr9_+_120466610 0.967 ENST00000394487.4
TLR4
toll-like receptor 4
chr15_+_67430339 0.965 ENST00000439724.3
SMAD3
SMAD family member 3
chr13_+_42031679 0.964 ENST00000379359.3
RGCC
regulator of cell cycle
chrX_-_135849484 0.959 ENST00000370620.1
ENST00000535227.1
ARHGEF6

Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6

chrX_+_70521584 0.953 ENST00000373829.3
ENST00000538820.1
ITGB1BP2

integrin beta 1 binding protein (melusin) 2

chr12_-_21810765 0.952 ENST00000450584.1
ENST00000350669.1
LDHB

lactate dehydrogenase B

chr19_-_3971050 0.942 ENST00000545797.2
ENST00000596311.1
DAPK3

death-associated protein kinase 3

chr9_+_127539481 0.935 ENST00000373580.3
OLFML2A
olfactomedin-like 2A
chr15_+_43809797 0.928 ENST00000399453.1
ENST00000300231.5
MAP1A

microtubule-associated protein 1A

chr4_-_159094194 0.927 ENST00000592057.1
ENST00000585682.1
ENST00000393807.5
FAM198B


family with sequence similarity 198, member B


chr11_+_111783450 0.926 ENST00000537382.1
HSPB2
Homo sapiens heat shock 27kDa protein 2 (HSPB2), mRNA.
chr7_+_79765071 0.914 ENST00000457358.2
GNAI1
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chr4_+_126237554 0.913 ENST00000394329.3
FAT4
FAT atypical cadherin 4
chr9_-_130966497 0.904 ENST00000393608.1
ENST00000372948.3
CIZ1

CDKN1A interacting zinc finger protein 1

chr20_+_43343886 0.903 ENST00000190983.4
WISP2
WNT1 inducible signaling pathway protein 2
chr14_-_103987679 0.902 ENST00000553610.1
CKB
creatine kinase, brain
chrX_-_48216101 0.902 ENST00000298396.2
ENST00000376893.3
SSX3

synovial sarcoma, X breakpoint 3

chr1_-_201476274 0.900 ENST00000340006.2
CSRP1
cysteine and glycine-rich protein 1
chr8_-_13372395 0.892 ENST00000276297.4
ENST00000511869.1
DLC1

deleted in liver cancer 1

chr3_+_46448648 0.890 ENST00000399036.3
CCRL2
chemokine (C-C motif) receptor-like 2
chr7_-_151433342 0.888 ENST00000433631.2
PRKAG2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr5_-_146781153 0.884 ENST00000520473.1
DPYSL3
dihydropyrimidinase-like 3
chr17_-_46688334 0.880 ENST00000239165.7
HOXB7
homeobox B7
chr4_-_7873981 0.876 ENST00000360265.4
AFAP1
actin filament associated protein 1
chr6_-_42016385 0.874 ENST00000502771.1
ENST00000508143.1
ENST00000514588.1
ENST00000510503.1
ENST00000415497.2
ENST00000372988.4
CCND3





cyclin D3





chr7_-_151433393 0.872 ENST00000492843.1
PRKAG2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr12_-_54694758 0.871 ENST00000553070.1
NFE2
nuclear factor, erythroid 2
chr12_+_102091400 0.870 ENST00000229266.3
ENST00000549872.1
CHPT1

choline phosphotransferase 1

chr12_-_6451186 0.864 ENST00000540022.1
ENST00000536194.1
TNFRSF1A

tumor necrosis factor receptor superfamily, member 1A

chr1_-_43855479 0.862 ENST00000290663.6
ENST00000372457.4
MED8

mediator complex subunit 8

chr16_-_69760409 0.857 ENST00000561500.1
ENST00000439109.2
ENST00000564043.1
ENST00000379046.2
ENST00000379047.3
NQO1




NAD(P)H dehydrogenase, quinone 1




chr11_-_321050 0.850 ENST00000399808.4
IFITM3
interferon induced transmembrane protein 3
chr5_+_149569520 0.849 ENST00000230671.2
ENST00000524041.1
SLC6A7

solute carrier family 6 (neurotransmitter transporter), member 7

chr1_-_95392635 0.847 ENST00000538964.1
ENST00000394202.4
ENST00000370206.4
CNN3


calponin 3, acidic


chr11_-_33744487 0.843 ENST00000426650.2
CD59
CD59 molecule, complement regulatory protein
chr3_-_138312971 0.835 ENST00000485115.1
ENST00000484888.1
ENST00000468900.1
ENST00000542237.1
ENST00000481834.1
CEP70




centrosomal protein 70kDa




chrX_+_152760397 0.832 ENST00000331595.4
ENST00000431891.1
BGN

biglycan

chr11_-_64014379 0.829 ENST00000309318.3
PPP1R14B
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr1_+_19923454 0.827 ENST00000322753.6
ENST00000602662.1
ENST00000602293.1
MINOS1
MINOS1-NBL1

mitochondrial inner membrane organizing system 1
MINOS1-NBL1 readthrough

chr1_-_43855444 0.821 ENST00000372455.4
MED8
mediator complex subunit 8
chr6_-_112575687 0.820 ENST00000521398.1
ENST00000424408.2
ENST00000243219.3
LAMA4


laminin, alpha 4


chr4_-_186696425 0.819 ENST00000430503.1
ENST00000319454.6
ENST00000450341.1
SORBS2


sorbin and SH3 domain containing 2


chr12_-_54694807 0.818 ENST00000435572.2
NFE2
nuclear factor, erythroid 2
chr3_-_52486841 0.816 ENST00000496590.1
TNNC1
troponin C type 1 (slow)
chr11_+_20044600 0.814 ENST00000311043.8
NAV2
neuron navigator 2
chr2_+_170366203 0.811 ENST00000284669.1
KLHL41
kelch-like family member 41
chr6_+_129204337 0.810 ENST00000421865.2
LAMA2
laminin, alpha 2
chr1_-_203151933 0.804 ENST00000404436.2
CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr22_+_31518938 0.796 ENST00000412985.1
ENST00000331075.5
ENST00000412277.2
ENST00000420017.1
ENST00000400294.2
ENST00000405300.1
ENST00000404390.3
INPP5J






inositol polyphosphate-5-phosphatase J






chr7_+_112063192 0.795 ENST00000005558.4
IFRD1
interferon-related developmental regulator 1
chr6_+_39760129 0.786 ENST00000274867.4
DAAM2
dishevelled associated activator of morphogenesis 2
chr13_+_48807288 0.785 ENST00000378565.5
ITM2B
integral membrane protein 2B
chr2_+_192141611 0.783 ENST00000392316.1
MYO1B
myosin IB

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.2 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
1.0 4.0 GO:0009956 radial pattern formation(GO:0009956)
0.9 10.1 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.9 3.4 GO:0043116 negative regulation of vascular permeability(GO:0043116)
0.8 11.9 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.7 4.3 GO:1901881 positive regulation of protein depolymerization(GO:1901881)
0.7 2.8 GO:0006089 lactate metabolic process(GO:0006089)
0.7 2.1 GO:0032707 negative regulation of interleukin-23 production(GO:0032707)
0.6 1.9 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.6 1.7 GO:0033484 nitric oxide homeostasis(GO:0033484)
0.5 1.6 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.5 1.5 GO:0006041 glucosamine metabolic process(GO:0006041)
0.5 1.4 GO:0007518 myoblast fate determination(GO:0007518)
0.4 1.3 GO:0046604 regulation of mitotic centrosome separation(GO:0046602) positive regulation of mitotic centrosome separation(GO:0046604)
0.4 2.1 GO:0007614 short-term memory(GO:0007614)
0.4 1.2 GO:0003308 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.4 1.2 GO:0042759 fatty acid elongation, saturated fatty acid(GO:0019367) long-chain fatty acid biosynthetic process(GO:0042759)
0.4 1.5 GO:0051013 microtubule severing(GO:0051013)
0.4 1.5 GO:0001780 neutrophil homeostasis(GO:0001780)
0.3 1.7 GO:0001955 blood vessel maturation(GO:0001955)
0.3 1.6 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.3 1.3 GO:0006787 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.3 1.3 GO:0002686 negative regulation of leukocyte migration(GO:0002686)
0.3 0.9 GO:2000105 positive regulation of DNA-dependent DNA replication initiation(GO:0032298) positive regulation of DNA-dependent DNA replication(GO:2000105)
0.3 0.3 GO:0007109 obsolete cytokinesis, completion of separation(GO:0007109)
0.3 0.3 GO:0003408 optic cup formation involved in camera-type eye development(GO:0003408)
0.3 2.7 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.3 1.5 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.3 1.2 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.3 0.9 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.3 0.6 GO:0048541 Peyer's patch development(GO:0048541)
0.3 0.8 GO:1903115 regulation of muscle filament sliding(GO:0032971) regulation of actin filament-based movement(GO:1903115)
0.3 2.3 GO:0010799 regulation of peptidyl-threonine phosphorylation(GO:0010799) positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.3 1.5 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.2 2.0 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.2 0.5 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.2 3.1 GO:0031498 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.2 1.2 GO:0019471 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.2 1.1 GO:0035444 nickel cation transport(GO:0015675) vanadium ion transport(GO:0015676) ferrous iron transport(GO:0015684) lead ion transport(GO:0015692) nickel cation transmembrane transport(GO:0035444) ferrous iron import(GO:0070627) iron ion import(GO:0097286)
0.2 1.3 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.2 0.7 GO:0048311 mitochondrion distribution(GO:0048311)
0.2 0.2 GO:0051589 negative regulation of neurotransmitter transport(GO:0051589)
0.2 0.9 GO:0045988 negative regulation of striated muscle contraction(GO:0045988)
0.2 0.8 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.2 1.0 GO:0048388 endosomal lumen acidification(GO:0048388)
0.2 1.2 GO:0022614 membrane to membrane docking(GO:0022614)
0.2 1.0 GO:0003070 age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070)
0.2 2.0 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.2 0.8 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.2 1.2 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.2 1.7 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.2 0.6 GO:0043371 negative regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043371) negative regulation of T-helper cell differentiation(GO:0045623) negative regulation of CD4-positive, alpha-beta T cell activation(GO:2000515)
0.2 3.8 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.2 1.1 GO:0014819 regulation of skeletal muscle contraction(GO:0014819)
0.2 3.0 GO:0042749 regulation of circadian sleep/wake cycle(GO:0042749) regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.2 1.1 GO:0010561 negative regulation of glycoprotein biosynthetic process(GO:0010561)
0.2 0.5 GO:0060574 trachea cartilage morphogenesis(GO:0060535) cartilage morphogenesis(GO:0060536) intestinal epithelial cell maturation(GO:0060574) intestinal epithelial cell development(GO:0060576)
0.2 1.0 GO:0045079 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665) negative regulation of chemokine biosynthetic process(GO:0045079)
0.2 0.5 GO:0071280 epithelial fluid transport(GO:0042045) cellular response to copper ion(GO:0071280)
0.2 0.5 GO:0045726 negative regulation of macrophage cytokine production(GO:0010936) regulation of integrin biosynthetic process(GO:0045113) positive regulation of integrin biosynthetic process(GO:0045726)
0.2 1.0 GO:0044413 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.2 1.1 GO:0015671 oxygen transport(GO:0015671)
0.2 3.9 GO:0045103 intermediate filament-based process(GO:0045103)
0.1 0.6 GO:0043501 skeletal muscle adaptation(GO:0043501)
0.1 0.3 GO:0032682 negative regulation of chemokine production(GO:0032682)
0.1 1.3 GO:0006020 inositol metabolic process(GO:0006020)
0.1 0.8 GO:0015824 proline transport(GO:0015824)
0.1 1.7 GO:0055015 ventricular cardiac muscle cell development(GO:0055015)
0.1 1.3 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.1 5.3 GO:0030325 adrenal gland development(GO:0030325)
0.1 1.0 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.1 0.1 GO:0060976 coronary vasculature development(GO:0060976)
0.1 0.3 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1 0.3 GO:0002685 regulation of leukocyte migration(GO:0002685)
0.1 1.8 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 0.4 GO:0032411 regulation of transporter activity(GO:0032409) positive regulation of transporter activity(GO:0032411)
0.1 0.5 GO:0015793 glycerol transport(GO:0015793)
0.1 2.5 GO:0030199 collagen fibril organization(GO:0030199)
0.1 2.7 GO:0006942 regulation of striated muscle contraction(GO:0006942)
0.1 1.5 GO:0051927 obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051927)
0.1 0.3 GO:0061117 cardiac chamber formation(GO:0003207) cardiac ventricle formation(GO:0003211) cardiac left ventricle formation(GO:0003218) negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of cardiac muscle tissue development(GO:0055026) negative regulation of cardiac muscle cell proliferation(GO:0060044) negative regulation of heart growth(GO:0061117)
0.1 0.3 GO:0045618 positive regulation of keratinocyte differentiation(GO:0045618)
0.1 3.1 GO:0043462 regulation of ATPase activity(GO:0043462)
0.1 0.3 GO:0010107 potassium ion import(GO:0010107)
0.1 1.4 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.1 1.2 GO:0006105 succinate metabolic process(GO:0006105)
0.1 0.2 GO:0035120 post-embryonic appendage morphogenesis(GO:0035120)
0.1 3.1 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.1 0.5 GO:0001880 Mullerian duct regression(GO:0001880)
0.1 0.6 GO:0007341 penetration of zona pellucida(GO:0007341)
0.1 2.0 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.1 2.5 GO:0007176 regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.1 1.1 GO:0032717 negative regulation of interleukin-8 production(GO:0032717)
0.1 0.4 GO:0001575 globoside metabolic process(GO:0001575)
0.1 0.5 GO:0008354 germ cell migration(GO:0008354)
0.1 0.6 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 0.1 GO:0001935 endothelial cell proliferation(GO:0001935)
0.1 0.4 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.1 1.6 GO:0050812 acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.1 0.2 GO:0042246 tissue regeneration(GO:0042246)
0.1 0.3 GO:0061084 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084) negative regulation of protein folding(GO:1903333)
0.1 0.4 GO:0008038 neuron recognition(GO:0008038)
0.1 1.0 GO:0006108 malate metabolic process(GO:0006108)
0.1 0.4 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.1 0.6 GO:0008212 mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
0.1 0.3 GO:0045214 sarcomere organization(GO:0045214)
0.1 0.8 GO:0002888 positive regulation of myeloid leukocyte mediated immunity(GO:0002888) positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of leukocyte degranulation(GO:0043302) positive regulation of mast cell degranulation(GO:0043306)
0.1 0.3 GO:0071374 cellular response to parathyroid hormone stimulus(GO:0071374)
0.1 1.0 GO:0060048 cardiac muscle contraction(GO:0060048)
0.1 0.2 GO:0097237 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.1 0.7 GO:0031000 response to caffeine(GO:0031000)
0.1 3.6 GO:0070585 protein localization to mitochondrion(GO:0070585)
0.1 0.4 GO:0003322 pancreatic A cell development(GO:0003322)
0.1 6.9 GO:0009408 response to heat(GO:0009408)
0.1 1.8 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 0.4 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.1 0.2 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.1 0.4 GO:0030644 cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.1 0.2 GO:0061188 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.1 0.8 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.1 0.4 GO:0015889 cobalamin transport(GO:0015889)
0.1 0.4 GO:0071361 cellular response to ethanol(GO:0071361)
0.1 1.0 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.1 0.1 GO:0070244 negative regulation of T cell apoptotic process(GO:0070233) negative regulation of thymocyte apoptotic process(GO:0070244)
0.1 1.2 GO:0007520 myoblast fusion(GO:0007520)
0.1 0.2 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417) positive regulation of pinocytosis(GO:0048549) positive regulation of sodium ion transmembrane transport(GO:1902307) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.1 0.2 GO:0060056 mammary gland involution(GO:0060056)
0.1 0.1 GO:0002002 regulation of angiotensin levels in blood(GO:0002002) regulation of angiotensin metabolic process(GO:0060177)
0.1 0.2 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.1 0.5 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.1 0.3 GO:0043113 receptor clustering(GO:0043113)
0.1 0.3 GO:0007059 chromosome segregation(GO:0007059)
0.1 0.3 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.1 2.2 GO:0050873 brown fat cell differentiation(GO:0050873)
0.1 1.3 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.1 0.9 GO:1904031 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.1 2.9 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 0.2 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 0.5 GO:0046628 positive regulation of insulin receptor signaling pathway(GO:0046628) positive regulation of cellular response to insulin stimulus(GO:1900078)
0.1 0.7 GO:0010226 response to lithium ion(GO:0010226)
0.1 0.1 GO:0048715 negative regulation of oligodendrocyte differentiation(GO:0048715)
0.1 0.1 GO:0048739 skeletal muscle myosin thick filament assembly(GO:0030241) myosin filament assembly(GO:0031034) cardiac muscle fiber development(GO:0048739) striated muscle myosin thick filament assembly(GO:0071688)
0.1 0.4 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.1 0.3 GO:0097435 extracellular fibril organization(GO:0043206) fibril organization(GO:0097435)
0.1 0.3 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509) plasma membrane to endosome transport(GO:0048227)
0.1 1.1 GO:0018208 peptidyl-proline modification(GO:0018208)
0.1 2.5 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.1 0.4 GO:0010812 negative regulation of cell-substrate adhesion(GO:0010812)
0.1 0.2 GO:0001552 ovarian follicle atresia(GO:0001552)
0.1 0.3 GO:0090103 cochlea morphogenesis(GO:0090103)
0.1 0.3 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.1 0.6 GO:1901072 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032) amino sugar catabolic process(GO:0046348) glucosamine-containing compound catabolic process(GO:1901072)
0.1 1.9 GO:0006941 striated muscle contraction(GO:0006941)
0.1 0.9 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.1 0.2 GO:0010536 regulation of activation of Janus kinase activity(GO:0010533) regulation of activation of JAK2 kinase activity(GO:0010534) positive regulation of activation of JAK2 kinase activity(GO:0010535) positive regulation of activation of Janus kinase activity(GO:0010536)
0.1 1.3 GO:0015813 L-glutamate transport(GO:0015813)
0.0 1.3 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.3 GO:0000239 pachytene(GO:0000239)
0.0 0.1 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.0 0.4 GO:0006998 nuclear envelope organization(GO:0006998)
0.0 0.1 GO:1902170 cellular response to nitric oxide(GO:0071732) cellular response to reactive nitrogen species(GO:1902170)
0.0 1.7 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.2 GO:0016199 axon midline choice point recognition(GO:0016199)
0.0 0.4 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.0 GO:0070857 regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.0 0.3 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.6 GO:0045161 neuronal ion channel clustering(GO:0045161)
0.0 0.9 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 0.3 GO:0007549 dosage compensation(GO:0007549)
0.0 0.2 GO:0060081 membrane hyperpolarization(GO:0060081)
0.0 0.2 GO:0030952 establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0 0.4 GO:0030903 notochord development(GO:0030903)
0.0 0.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.2 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.5 GO:0043537 negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.0 0.2 GO:0018101 protein citrullination(GO:0018101)
0.0 0.1 GO:0070672 response to interleukin-15(GO:0070672)
0.0 0.3 GO:0032410 negative regulation of transporter activity(GO:0032410)
0.0 0.0 GO:0006304 DNA modification(GO:0006304)
0.0 0.4 GO:1901798 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0 0.1 GO:0034339 obsolete regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor(GO:0034339)
0.0 0.5 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.9 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.2 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.4 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 1.1 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111) regulation of microtubule depolymerization(GO:0031114)
0.0 0.1 GO:0034122 negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.0 0.3 GO:0019321 pentose metabolic process(GO:0019321)
0.0 1.5 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 2.2 GO:0006914 autophagy(GO:0006914)
0.0 0.4 GO:0046688 response to copper ion(GO:0046688)
0.0 0.2 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.5 GO:0010165 response to X-ray(GO:0010165)
0.0 0.2 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 7.9 GO:0007517 muscle organ development(GO:0007517)
0.0 1.2 GO:0007368 determination of left/right symmetry(GO:0007368)
0.0 0.6 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.0 0.5 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.2 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.3 GO:0070509 calcium ion import(GO:0070509)
0.0 0.2 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.3 GO:0042117 monocyte activation(GO:0042117)
0.0 0.1 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.0 1.1 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 0.3 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.6 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.2 GO:0006999 nuclear pore organization(GO:0006999)
0.0 1.2 GO:0060338 regulation of type I interferon-mediated signaling pathway(GO:0060338)
0.0 0.1 GO:0015742 dicarboxylic acid transport(GO:0006835) alpha-ketoglutarate transport(GO:0015742)
0.0 0.5 GO:0045446 endothelium development(GO:0003158) endothelial cell differentiation(GO:0045446)
0.0 0.2 GO:0015802 basic amino acid transport(GO:0015802)
0.0 0.1 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.0 1.3 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.0 1.0 GO:0006937 regulation of muscle contraction(GO:0006937)
0.0 0.3 GO:0019835 cytolysis(GO:0019835)
0.0 0.9 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 1.0 GO:0051101 regulation of DNA binding(GO:0051101)
0.0 0.2 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.2 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi vesicle budding(GO:0048194) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.1 GO:0009992 cellular water homeostasis(GO:0009992)
0.0 0.1 GO:0030035 microspike assembly(GO:0030035)
0.0 0.1 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.4 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.2 GO:0098927 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0 0.4 GO:0010595 positive regulation of endothelial cell migration(GO:0010595)
0.0 0.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.1 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051) regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.1 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.2 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.5 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.4 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.3 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 1.0 GO:0007569 cell aging(GO:0007569)
0.0 0.8 GO:0001501 skeletal system development(GO:0001501)
0.0 0.1 GO:0015959 diadenosine polyphosphate metabolic process(GO:0015959)
0.0 0.3 GO:0007567 parturition(GO:0007567)
0.0 0.2 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.5 GO:0051149 positive regulation of muscle cell differentiation(GO:0051149)
0.0 0.1 GO:0006848 pyruvate transport(GO:0006848)
0.0 0.3 GO:0060761 negative regulation of response to cytokine stimulus(GO:0060761)
0.0 0.9 GO:0008016 regulation of heart contraction(GO:0008016)
0.0 0.1 GO:0021548 pons development(GO:0021548)
0.0 0.0 GO:0060602 branch elongation of an epithelium(GO:0060602)
0.0 0.6 GO:0044349 nucleotide-excision repair, DNA damage removal(GO:0000718) DNA excision(GO:0044349)
0.0 0.1 GO:0071482 cellular response to light stimulus(GO:0071482)
0.0 0.5 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.1 GO:0015854 guanine transport(GO:0015854) pyrimidine nucleobase transport(GO:0015855) hypoxanthine transport(GO:0035344) thymine transport(GO:0035364)
0.0 0.1 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.2 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.1 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.1 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.0 0.3 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.1 GO:0031282 regulation of guanylate cyclase activity(GO:0031282)
0.0 0.2 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.1 GO:1903301 regulation of glucokinase activity(GO:0033131) positive regulation of glucokinase activity(GO:0033133) regulation of hexokinase activity(GO:1903299) positive regulation of hexokinase activity(GO:1903301)
0.0 0.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.3 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.2 GO:0043161 proteasomal protein catabolic process(GO:0010498) proteasome-mediated ubiquitin-dependent protein catabolic process(GO:0043161)
0.0 0.0 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.0 0.4 GO:0038179 neurotrophin signaling pathway(GO:0038179) neurotrophin TRK receptor signaling pathway(GO:0048011)
0.0 0.2 GO:0006469 negative regulation of protein kinase activity(GO:0006469)
0.0 0.7 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) negative regulation of ERBB signaling pathway(GO:1901185)
0.0 0.1 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.9 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.2 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.0 0.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 1.4 GO:0044819 mitotic G1 DNA damage checkpoint(GO:0031571) G1 DNA damage checkpoint(GO:0044783) mitotic G1/S transition checkpoint(GO:0044819)
0.0 0.1 GO:1903513 retrograde protein transport, ER to cytosol(GO:0030970) protein exit from endoplasmic reticulum(GO:0032527) endoplasmic reticulum to cytosol transport(GO:1903513)
0.0 0.8 GO:0030198 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 0.0 GO:0051299 centrosome separation(GO:0051299)
0.0 0.6 GO:0050931 melanocyte differentiation(GO:0030318) pigment cell differentiation(GO:0050931)
0.0 0.1 GO:0070243 regulation of T cell apoptotic process(GO:0070232) thymocyte apoptotic process(GO:0070242) regulation of thymocyte apoptotic process(GO:0070243)
0.0 0.1 GO:0030323 respiratory tube development(GO:0030323)
0.0 2.5 GO:0001525 angiogenesis(GO:0001525)
0.0 0.3 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.3 GO:0006029 proteoglycan metabolic process(GO:0006029)
0.0 0.4 GO:0000725 double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
0.0 2.1 GO:0044839 G2/M transition of mitotic cell cycle(GO:0000086) cell cycle G2/M phase transition(GO:0044839)
0.0 0.1 GO:0007032 endosome organization(GO:0007032)
0.0 0.6 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 2.3 GO:0050658 nucleic acid transport(GO:0050657) RNA transport(GO:0050658) establishment of RNA localization(GO:0051236)
0.0 1.1 GO:0006865 amino acid transport(GO:0006865)
0.0 1.2 GO:0006936 muscle contraction(GO:0006936)
0.0 0.2 GO:0006743 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744)
0.0 0.1 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.0 GO:0007285 primary spermatocyte growth(GO:0007285)
0.0 2.0 GO:0071466 xenobiotic metabolic process(GO:0006805) response to xenobiotic stimulus(GO:0009410) cellular response to xenobiotic stimulus(GO:0071466)
0.0 0.2 GO:0008542 visual learning(GO:0008542)
0.0 0.2 GO:0051225 spindle assembly(GO:0051225)
0.0 0.0 GO:0006788 heme oxidation(GO:0006788)
0.0 1.2 GO:0034329 cell junction assembly(GO:0034329)
0.0 0.1 GO:0016572 histone phosphorylation(GO:0016572)
0.0 0.1 GO:0015858 nucleoside transport(GO:0015858)
0.0 0.0 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.0 GO:0015853 purine nucleobase transport(GO:0006863) adenine transport(GO:0015853)
0.0 0.5 GO:0048704 embryonic skeletal system morphogenesis(GO:0048704)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.7 GO:0005607 laminin-2 complex(GO:0005607)
0.9 12.4 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.8 2.5 GO:0005588 collagen type V trimer(GO:0005588)
0.5 1.6 GO:0043226 organelle(GO:0043226)
0.5 5.9 GO:0031527 filopodium membrane(GO:0031527)
0.4 2.6 GO:0070435 Shc-EGFR complex(GO:0070435)
0.4 2.0 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.3 3.0 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.3 1.8 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.3 1.2 GO:0045257 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.3 1.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.3 0.3 GO:0019717 obsolete synaptosome(GO:0019717)
0.2 1.7 GO:0000300 obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.2 1.1 GO:0070826 paraferritin complex(GO:0070826)
0.2 2.0 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.2 0.2 GO:0030315 T-tubule(GO:0030315)
0.2 3.8 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.2 1.6 GO:0005587 collagen type IV trimer(GO:0005587)
0.2 2.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.2 1.7 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.2 0.9 GO:0005602 complement component C1 complex(GO:0005602)
0.2 0.5 GO:0030904 retromer complex(GO:0030904)
0.2 0.5 GO:0033655 host(GO:0018995) host cell cytoplasm(GO:0030430) host cell part(GO:0033643) host intracellular part(GO:0033646) host cell cytoplasm part(GO:0033655) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.2 2.1 GO:0005833 hemoglobin complex(GO:0005833)
0.2 2.4 GO:0005859 muscle myosin complex(GO:0005859)
0.2 0.9 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.1 2.5 GO:0031528 microvillus membrane(GO:0031528)
0.1 0.9 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 1.9 GO:0005606 laminin-1 complex(GO:0005606)
0.1 0.4 GO:0043159 acrosomal matrix(GO:0043159)
0.1 0.8 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 0.3 GO:0005771 multivesicular body(GO:0005771)
0.1 1.8 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.1 1.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 2.9 GO:0043034 costamere(GO:0043034)
0.1 0.9 GO:0031594 neuromuscular junction(GO:0031594)
0.1 1.8 GO:0001527 microfibril(GO:0001527)
0.1 3.3 GO:0005811 lipid particle(GO:0005811)
0.1 0.5 GO:0098984 asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.1 0.4 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.1 2.6 GO:0005865 striated muscle thin filament(GO:0005865)
0.1 1.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 1.2 GO:0005626 obsolete insoluble fraction(GO:0005626)
0.1 1.9 GO:0032982 myosin filament(GO:0032982)
0.1 1.2 GO:0000421 autophagosome membrane(GO:0000421)
0.1 1.0 GO:0005577 fibrinogen complex(GO:0005577)
0.1 4.8 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 0.5 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.1 1.2 GO:0031143 pseudopodium(GO:0031143)
0.1 7.1 GO:0005882 intermediate filament(GO:0005882)
0.1 3.3 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 0.3 GO:0036125 mitochondrial fatty acid beta-oxidation multienzyme complex(GO:0016507) fatty acid beta-oxidation multienzyme complex(GO:0036125)
0.1 0.3 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.1 0.2 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.1 0.9 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 0.3 GO:0001740 Barr body(GO:0001740)
0.1 1.5 GO:0005902 microvillus(GO:0005902)
0.1 7.2 GO:0030016 myofibril(GO:0030016)
0.1 0.2 GO:0070695 FHF complex(GO:0070695)
0.1 1.0 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.1 0.2 GO:0014802 terminal cisterna(GO:0014802) endoplasmic reticulum subcompartment(GO:0098827)
0.1 1.6 GO:0016592 mediator complex(GO:0016592)
0.1 0.4 GO:0042382 paraspeckles(GO:0042382)
0.1 2.5 GO:0098636 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.1 0.3 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.4 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.2 GO:0000124 SAGA complex(GO:0000124)
0.0 0.2 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.8 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.4 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 1.8 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 1.2 GO:0090568 NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)
0.0 1.9 GO:0030286 dynein complex(GO:0030286)
0.0 0.4 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.0 2.4 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.3 GO:0042597 outer membrane-bounded periplasmic space(GO:0030288) periplasmic space(GO:0042597)
0.0 0.3 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.3 GO:0042788 polysomal ribosome(GO:0042788)
0.0 1.4 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.3 GO:0043205 fibril(GO:0043205)
0.0 0.9 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.0 0.3 GO:0030897 HOPS complex(GO:0030897)
0.0 0.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.2 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.0 1.2 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.8 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.2 GO:0070552 BRISC complex(GO:0070552)
0.0 3.0 GO:0016605 PML body(GO:0016605)
0.0 0.4 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 4.1 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 1.6 GO:0016459 myosin complex(GO:0016459)
0.0 0.3 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 1.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.1 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 1.7 GO:1902554 serine/threonine protein kinase complex(GO:1902554)
0.0 0.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 1.2 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 0.1 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.4 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.6 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.3 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.2 GO:0030992 intraciliary transport particle(GO:0030990) intraciliary transport particle B(GO:0030992)
0.0 0.3 GO:0033177 proton-transporting two-sector ATPase complex, proton-transporting domain(GO:0033177)
0.0 0.1 GO:0042599 lamellar body(GO:0042599)
0.0 0.6 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.8 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 1.9 GO:0001726 ruffle(GO:0001726)
0.0 0.1 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.3 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 1.3 GO:0005802 trans-Golgi network(GO:0005802)
0.0 1.5 GO:0008287 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0 10.3 GO:0009986 cell surface(GO:0009986)
0.0 2.4 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 3.3 GO:0005925 focal adhesion(GO:0005925)
0.0 0.1 GO:0031213 RSF complex(GO:0031213)
0.0 0.2 GO:0000125 PCAF complex(GO:0000125)
0.0 0.2 GO:0071778 obsolete WINAC complex(GO:0071778)
0.0 5.0 GO:0005813 centrosome(GO:0005813)
0.0 0.1 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 0.3 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267)
0.0 0.3 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.1 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 1.2 GO:0005875 microtubule associated complex(GO:0005875)
0.0 0.3 GO:0043235 receptor complex(GO:0043235)
0.0 4.5 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.3 GO:0016234 inclusion body(GO:0016234)
0.0 0.1 GO:0030914 STAGA complex(GO:0030914)
0.0 0.2 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.6 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.0 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 1.1 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.3 GO:0019215 intermediate filament binding(GO:0019215)
0.8 3.1 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.6 1.9 GO:0070052 collagen V binding(GO:0070052)
0.6 2.3 GO:0048039 ubiquinone binding(GO:0048039)
0.5 2.2 GO:0008112 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.5 1.6 GO:0048184 obsolete follistatin binding(GO:0048184)
0.4 0.4 GO:0042806 fucose binding(GO:0042806)
0.4 2.4 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.4 15.8 GO:0050840 extracellular matrix binding(GO:0050840)
0.4 2.8 GO:0004457 lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
0.4 0.8 GO:0001540 beta-amyloid binding(GO:0001540)
0.4 1.9 GO:0004741 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724) [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.3 2.0 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.3 1.3 GO:0004473 malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.3 3.5 GO:0030274 LIM domain binding(GO:0030274)
0.3 1.3 GO:0004074 biliverdin reductase activity(GO:0004074)
0.3 3.4 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.3 1.5 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.3 0.8 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.3 1.1 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.3 3.6 GO:0003706 obsolete ligand-regulated transcription factor activity(GO:0003706)
0.3 0.8 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.3 6.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.2 1.7 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.2 1.5 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.2 1.5 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.2 3.1 GO:0005344 oxygen transporter activity(GO:0005344)
0.2 1.2 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.2 1.2 GO:0009922 fatty acid elongase activity(GO:0009922)
0.2 2.3 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.2 1.1 GO:0015087 cobalt ion transmembrane transporter activity(GO:0015087) ferrous iron transmembrane transporter activity(GO:0015093) lead ion transmembrane transporter activity(GO:0015094) nickel cation transmembrane transporter activity(GO:0015099) vanadium ion transmembrane transporter activity(GO:0015100) chromium ion transmembrane transporter activity(GO:0070835)
0.2 2.0 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.2 3.3 GO:0004017 adenylate kinase activity(GO:0004017)
0.2 0.9 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.2 1.6 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.2 1.2 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.2 2.7 GO:0004065 arylsulfatase activity(GO:0004065)
0.2 1.8 GO:0030172 troponin C binding(GO:0030172)
0.2 2.0 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.2 1.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.2 3.6 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.2 0.5 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.2 1.7 GO:0017154 semaphorin receptor activity(GO:0017154)
0.2 0.5 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.2 0.5 GO:0047708 biotinidase activity(GO:0047708)
0.2 1.0 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 1.2 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 0.9 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 1.0 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.1 0.9 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 0.7 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.5 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.1 0.5 GO:0015254 urea transmembrane transporter activity(GO:0015204) glycerol channel activity(GO:0015254)
0.1 4.3 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.1 3.7 GO:0005518 collagen binding(GO:0005518)
0.1 0.8 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 1.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.6 GO:0004111 creatine kinase activity(GO:0004111)
0.1 0.5 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.1 0.3 GO:0032089 NACHT domain binding(GO:0032089)
0.1 0.3 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 0.3 GO:0004769 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854) steroid delta-isomerase activity(GO:0004769)
0.1 10.0 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 1.5 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.1 0.6 GO:0031013 troponin I binding(GO:0031013)
0.1 0.8 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.1 1.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.1 GO:0022884 macromolecule transmembrane transporter activity(GO:0022884)
0.1 1.2 GO:0030547 receptor inhibitor activity(GO:0030547) receptor antagonist activity(GO:0048019)
0.1 3.4 GO:1990782 receptor tyrosine kinase binding(GO:0030971) protein tyrosine kinase binding(GO:1990782)
0.1 1.2 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 0.4 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.1 0.9 GO:0046870 cadmium ion binding(GO:0046870)
0.1 9.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 0.6 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 0.3 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.1 0.9 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 0.8 GO:0050811 GABA receptor binding(GO:0050811)
0.1 0.4 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979) core promoter sequence-specific DNA binding(GO:0001046) core promoter binding(GO:0001047)
0.1 1.2 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 0.5 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.1 4.2 GO:0050136 NADH dehydrogenase activity(GO:0003954) NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.7 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 0.3 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.1 0.8 GO:0031701 angiotensin receptor binding(GO:0031701)
0.1 1.3 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1 0.3 GO:0002162 dystroglycan binding(GO:0002162)
0.1 1.3 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.1 1.1 GO:0017166 vinculin binding(GO:0017166)
0.1 0.2 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.1 0.4 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.1 0.2 GO:0004797 thymidine kinase activity(GO:0004797)
0.1 0.3 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.1 0.2 GO:0016418 S-acetyltransferase activity(GO:0016418)
0.1 0.9 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1 0.2 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.1 0.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.2 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.1 0.6 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.1 0.5 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510) bicarbonate transmembrane transporter activity(GO:0015106)
0.1 0.3 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 0.2 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
0.1 1.6 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.1 0.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 0.5 GO:0008235 metalloexopeptidase activity(GO:0008235)
0.1 1.9 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 1.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.2 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328) N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.1 1.8 GO:0050699 WW domain binding(GO:0050699)
0.1 1.0 GO:0008536 Ran GTPase binding(GO:0008536)
0.1 0.3 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.1 0.7 GO:0001076 transcription factor activity, RNA polymerase II transcription factor binding(GO:0001076)
0.1 0.5 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.1 0.1 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 0.3 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.1 0.2 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 0.3 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 0.6 GO:0003711 obsolete transcription elongation regulator activity(GO:0003711)
0.1 1.1 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.0 0.3 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.4 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 3.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.3 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 1.3 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.2 GO:0051920 peroxiredoxin activity(GO:0051920)
0.0 0.2 GO:0001968 fibronectin binding(GO:0001968)
0.0 1.6 GO:0001637 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 0.6 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 1.0 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.6 GO:0003690 double-stranded DNA binding(GO:0003690)
0.0 1.1 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.2 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.0 0.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.2 GO:0030492 hemoglobin binding(GO:0030492)
0.0 1.6 GO:0002020 protease binding(GO:0002020)
0.0 0.2 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.1 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.1 GO:0000150 recombinase activity(GO:0000150)
0.0 0.1 GO:0004771 sterol esterase activity(GO:0004771)
0.0 0.3 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.4 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.1 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.2 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.3 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.2 GO:0034597 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) phosphatidylinositol phosphate 4-phosphatase activity(GO:0034596) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.2 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.2 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.2 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.1 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.0 0.5 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 1.1 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769)
0.0 0.1 GO:0015389 pyrimidine nucleobase transmembrane transporter activity(GO:0005350) pyrimidine- and adenine-specific:sodium symporter activity(GO:0015389)
0.0 0.1 GO:0004730 pseudouridylate synthase activity(GO:0004730)
0.0 0.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.2 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.1 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0 0.1 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.2 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.2 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.1 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.0 0.8 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.5 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.7 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.3 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.4 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.8 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.3 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.3 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.8 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 5.5 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.1 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.4 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.0 0.2 GO:0031996 thioesterase binding(GO:0031996)
0.0 2.9 GO:0008201 heparin binding(GO:0008201)
0.0 0.5 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.1 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.1 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 0.1 GO:0045182 translation regulator activity(GO:0045182)
0.0 0.2 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.4 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.2 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.2 GO:0031014 troponin T binding(GO:0031014)
0.0 0.1 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.0 0.4 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 1.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.4 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.1 GO:0050833 pyruvate secondary active transmembrane transporter activity(GO:0005477) pyruvate transmembrane transporter activity(GO:0050833)
0.0 0.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.4 GO:0030553 cGMP binding(GO:0030553)
0.0 0.3 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0 0.5 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.3 GO:0008494 translation activator activity(GO:0008494)
0.0 1.7 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 3.3 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.1 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.5 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 0.0 GO:0005534 galactose binding(GO:0005534)
0.0 0.2 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.2 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.4 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.4 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.0 GO:0070568 guanylyltransferase activity(GO:0070568)
0.0 0.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.3 GO:0008173 RNA methyltransferase activity(GO:0008173)
0.0 0.0 GO:0005224 ATP-binding and phosphorylation-dependent chloride channel activity(GO:0005224) channel-conductance-controlling ATPase activity(GO:0005260)
0.0 0.0 GO:0005345 purine nucleobase transmembrane transporter activity(GO:0005345)
0.0 0.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.2 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 1.9 GO:0003774 motor activity(GO:0003774)
0.0 0.2 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.2 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.5 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 1.1 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.1 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.1 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.1 GO:0051378 serotonin binding(GO:0051378)
0.0 0.1 GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0 0.1 GO:0051636 obsolete Gram-negative bacterial cell surface binding(GO:0051636)
0.0 0.2 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 1.1 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 1.8 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.1 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.1 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 2.2 GO:0005125 cytokine activity(GO:0005125)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.1 GO:0019864 IgG binding(GO:0019864)
0.0 0.3 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.3 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.1 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.2 GO:0008013 beta-catenin binding(GO:0008013)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.8 ST_IL_13_PATHWAY Interleukin 13 (IL-13) Pathway
0.1 3.7 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 3.8 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 1.2 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 4.2 ST_INTEGRIN_SIGNALING_PATHWAY Integrin Signaling Pathway
0.0 1.1 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.5 SIG_CHEMOTAXIS Genes related to chemotaxis
0.0 0.9 SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES Genes related to the insulin receptor pathway
0.0 0.2 SA_G1_AND_S_PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.