Motif ID: RBPJ
Z-value: 0.811
Transcription factors associated with RBPJ:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| RBPJ | ENSG00000168214.16 | RBPJ |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 1.5 | GO:0019731 | antibacterial humoral response(GO:0019731) |
| 0.2 | 0.5 | GO:0043006 | activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006) |
| 0.1 | 0.5 | GO:0045218 | zonula adherens maintenance(GO:0045218) |
| 0.1 | 0.3 | GO:0006348 | chromatin silencing at telomere(GO:0006348) |
| 0.1 | 0.5 | GO:0022038 | corpus callosum development(GO:0022038) |
| 0.1 | 1.4 | GO:1902603 | carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603) |
| 0.0 | 0.3 | GO:0046541 | saliva secretion(GO:0046541) |
| 0.0 | 0.2 | GO:0032754 | positive regulation of interleukin-13 production(GO:0032736) positive regulation of interleukin-5 production(GO:0032754) |
| 0.0 | 0.7 | GO:0033687 | osteoblast proliferation(GO:0033687) |
| 0.0 | 0.1 | GO:0071883 | adrenergic receptor signaling pathway(GO:0071875) activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883) |
| 0.0 | 0.2 | GO:0006552 | leucine catabolic process(GO:0006552) |
| 0.0 | 0.1 | GO:0019046 | release from viral latency(GO:0019046) |
| 0.0 | 1.0 | GO:0050850 | positive regulation of calcium-mediated signaling(GO:0050850) |
| 0.0 | 0.3 | GO:0032876 | regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023) |
| 0.0 | 0.9 | GO:0046847 | filopodium assembly(GO:0046847) |
| 0.0 | 0.1 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
| 0.0 | 0.7 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
| 0.0 | 0.1 | GO:0045116 | protein neddylation(GO:0045116) |
| 0.0 | 0.7 | GO:0030837 | negative regulation of actin filament polymerization(GO:0030837) |
| 0.0 | 0.1 | GO:0070059 | intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059) |
| 0.0 | 1.4 | GO:0006754 | ATP biosynthetic process(GO:0006754) |
| 0.0 | 0.1 | GO:0007221 | positive regulation of transcription of Notch receptor target(GO:0007221) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.5 | GO:0042589 | phagocytic vesicle membrane(GO:0030670) zymogen granule membrane(GO:0042589) |
| 0.1 | 1.4 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.1 | 0.5 | GO:0070435 | Shc-EGFR complex(GO:0070435) |
| 0.1 | 0.4 | GO:0001739 | sex chromatin(GO:0001739) |
| 0.0 | 0.3 | GO:0005677 | chromatin silencing complex(GO:0005677) |
| 0.0 | 0.4 | GO:0005915 | zonula adherens(GO:0005915) |
| 0.0 | 0.1 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
| 0.0 | 0.5 | GO:0016592 | mediator complex(GO:0016592) |
| 0.0 | 0.1 | GO:0005687 | U4 snRNP(GO:0005687) |
| 0.0 | 0.1 | GO:0048188 | Set1C/COMPASS complex(GO:0048188) |
| 0.0 | 0.3 | GO:0043034 | costamere(GO:0043034) |
| 0.0 | 0.4 | GO:0097014 | axoneme(GO:0005930) ciliary plasm(GO:0097014) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.5 | GO:0051637 | obsolete Gram-positive bacterial cell surface binding(GO:0051637) |
| 0.1 | 0.3 | GO:0042903 | tubulin deacetylase activity(GO:0042903) |
| 0.1 | 0.5 | GO:0005006 | epidermal growth factor-activated receptor activity(GO:0005006) |
| 0.0 | 0.3 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
| 0.0 | 0.7 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
| 0.0 | 0.1 | GO:0004938 | alpha2-adrenergic receptor activity(GO:0004938) heterotrimeric G-protein binding(GO:0032795) |
| 0.0 | 0.1 | GO:0004946 | bombesin receptor activity(GO:0004946) |
| 0.0 | 1.0 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 0.0 | 0.3 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
| 0.0 | 0.2 | GO:0004738 | pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739) |
| 0.0 | 0.2 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
| 0.0 | 0.5 | GO:0016641 | oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641) |
| 0.0 | 0.2 | GO:0004427 | inorganic diphosphatase activity(GO:0004427) |
| 0.0 | 1.0 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 0.0 | 0.1 | GO:0003920 | GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657) |
| 0.0 | 0.1 | GO:0030621 | U4 snRNA binding(GO:0030621) |
| 0.0 | 0.5 | GO:0001104 | RNA polymerase II transcription cofactor activity(GO:0001104) |
| 0.0 | 0.3 | GO:0005537 | mannose binding(GO:0005537) |
| 0.0 | 0.1 | GO:0000150 | recombinase activity(GO:0000150) |
| 0.0 | 0.3 | GO:0019992 | diacylglycerol binding(GO:0019992) |
| 0.0 | 0.2 | GO:0003995 | acyl-CoA dehydrogenase activity(GO:0003995) |
| 0.0 | 0.1 | GO:0004332 | fructose-bisphosphate aldolase activity(GO:0004332) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.7 | ST_ERK1_ERK2_MAPK_PATHWAY | ERK1/ERK2 MAPK Pathway |
