Motif ID: RELA

Z-value: 1.863


Transcription factors associated with RELA:

Gene SymbolEntrez IDGene Name
RELA ENSG00000173039.14 RELA



Activity profile for motif RELA.

activity profile for motif RELA


Sorted Z-values histogram for motif RELA

Sorted Z-values for motif RELA



Network of associatons between targets according to the STRING database.



First level regulatory network of RELA

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_-_149792295 5.925 ENST00000518797.1
ENST00000524315.1
ENST00000009530.7
ENST00000377795.3
CD74



CD74 molecule, major histocompatibility complex, class II invariant chain



chr11_+_102188272 5.473 ENST00000532808.1
BIRC3
baculoviral IAP repeat containing 3
chr11_+_102188224 5.239 ENST00000263464.3
BIRC3
baculoviral IAP repeat containing 3
chr12_-_9913489 5.100 ENST00000228434.3
ENST00000536709.1
CD69

CD69 molecule

chr14_+_75988851 5.087 ENST00000555504.1
BATF
basic leucine zipper transcription factor, ATF-like
chr19_-_6591113 4.886 ENST00000423145.3
ENST00000245903.3
CD70

CD70 molecule

chr6_+_138188551 4.681 ENST00000237289.4
ENST00000433680.1
TNFAIP3

tumor necrosis factor, alpha-induced protein 3

chr22_-_37545972 4.404 ENST00000216223.5
IL2RB
interleukin 2 receptor, beta
chr6_+_32605134 4.369 ENST00000343139.5
ENST00000395363.1
ENST00000496318.1
HLA-DQA1


major histocompatibility complex, class II, DQ alpha 1


chr6_+_32605195 4.344 ENST00000374949.2
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chr11_-_58345569 3.972 ENST00000528954.1
ENST00000528489.1
LPXN

leupaxin

chr14_-_35873856 3.761 ENST00000553342.1
ENST00000216797.5
ENST00000557140.1
NFKBIA


nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha


chr20_+_44746885 3.350 ENST00000372285.3
CD40
CD40 molecule, TNF receptor superfamily member 5
chr7_+_69064300 3.077 ENST00000342771.4
AUTS2
autism susceptibility candidate 2
chr4_-_76944621 2.847 ENST00000306602.1
CXCL10
chemokine (C-X-C motif) ligand 10
chr6_-_32636145 2.797 ENST00000399084.1
HLA-DQB1
major histocompatibility complex, class II, DQ beta 1
chr3_-_158390282 2.704 ENST00000264265.3
LXN
latexin
chr19_+_4229495 2.649 ENST00000221847.5
EBI3
Epstein-Barr virus induced 3
chr4_+_103422471 2.607 ENST00000226574.4
ENST00000394820.4
NFKB1

nuclear factor of kappa light polypeptide gene enhancer in B-cells 1

chr22_-_37640277 2.605 ENST00000401529.3
ENST00000249071.6
RAC2

ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)

chr6_-_31550192 2.565 ENST00000429299.2
ENST00000446745.2
LTB

lymphotoxin beta (TNF superfamily, member 3)

chr4_-_40631859 2.557 ENST00000295971.7
ENST00000319592.4
RBM47

RNA binding motif protein 47

chr10_+_30722866 2.443 ENST00000263056.1
MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr20_-_4795747 2.412 ENST00000379376.2
RASSF2
Ras association (RalGDS/AF-6) domain family member 2
chr14_+_75988768 2.399 ENST00000286639.6
BATF
basic leucine zipper transcription factor, ATF-like
chr2_-_191885686 2.387 ENST00000432058.1
STAT1
signal transducer and activator of transcription 1, 91kDa
chr22_-_37640456 2.254 ENST00000405484.1
ENST00000441619.1
ENST00000406508.1
RAC2


ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)


chr16_+_50776021 2.202 ENST00000566679.2
ENST00000564634.1
ENST00000398568.2
CYLD


cylindromatosis (turban tumor syndrome)


chr14_+_103243813 2.099 ENST00000560371.1
ENST00000347662.4
ENST00000392745.2
ENST00000539721.1
ENST00000560463.1
TRAF3




TNF receptor-associated factor 3




chr6_+_29691198 2.092 ENST00000440587.2
ENST00000434407.2
HLA-F

major histocompatibility complex, class I, F

chr6_+_31540056 2.065 ENST00000418386.2
LTA
lymphotoxin alpha
chr12_+_7055631 2.035 ENST00000543115.1
ENST00000399448.1
PTPN6

protein tyrosine phosphatase, non-receptor type 6

chr7_-_24797032 2.026 ENST00000409970.1
ENST00000409775.3
DFNA5

deafness, autosomal dominant 5

chrX_-_73072534 2.001 ENST00000429829.1
XIST
X inactive specific transcript (non-protein coding)
chr14_+_61789382 1.968 ENST00000555082.1
PRKCH
protein kinase C, eta
chr6_-_29527702 1.947 ENST00000377050.4
UBD
ubiquitin D
chr6_+_29691056 1.873 ENST00000414333.1
ENST00000334668.4
ENST00000259951.7
HLA-F


major histocompatibility complex, class I, F


chr10_+_12391481 1.873 ENST00000378847.3
CAMK1D
calcium/calmodulin-dependent protein kinase ID
chr19_+_42381173 1.851 ENST00000221972.3
CD79A
CD79a molecule, immunoglobulin-associated alpha
chr7_-_24797546 1.847 ENST00000414428.1
ENST00000419307.1
ENST00000342947.3
DFNA5


deafness, autosomal dominant 5


chr1_+_111770278 1.799 ENST00000369748.4
CHI3L2
chitinase 3-like 2
chr1_+_111770232 1.778 ENST00000369744.2
CHI3L2
chitinase 3-like 2
chr19_+_42381337 1.771 ENST00000597454.1
ENST00000444740.2
CD79A

CD79a molecule, immunoglobulin-associated alpha

chr6_+_29910301 1.771 ENST00000376809.5
ENST00000376802.2
HLA-A

major histocompatibility complex, class I, A

chr19_+_2476116 1.736 ENST00000215631.4
ENST00000587345.1
GADD45B

growth arrest and DNA-damage-inducible, beta

chr19_-_7766991 1.729 ENST00000597921.1
ENST00000346664.5
FCER2

Fc fragment of IgE, low affinity II, receptor for (CD23)

chr19_-_11688447 1.725 ENST00000590420.1
ACP5
acid phosphatase 5, tartrate resistant
chr2_+_61108650 1.665 ENST00000295025.8
REL
v-rel avian reticuloendotheliosis viral oncogene homolog
chr2_-_163175133 1.641 ENST00000421365.2
ENST00000263642.2
IFIH1

interferon induced with helicase C domain 1

chr20_+_9494987 1.550 ENST00000427562.2
ENST00000246070.2
LAMP5

lysosomal-associated membrane protein family, member 5

chr10_+_104155450 1.539 ENST00000471698.1
ENST00000189444.6
NFKB2

nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)

chr4_-_76928641 1.527 ENST00000264888.5
CXCL9
chemokine (C-X-C motif) ligand 9
chr16_+_50775971 1.508 ENST00000311559.9
ENST00000564326.1
ENST00000566206.1
CYLD


cylindromatosis (turban tumor syndrome)


chr5_-_150460539 1.485 ENST00000520931.1
ENST00000520695.1
ENST00000521591.1
ENST00000518977.1
TNIP1



TNFAIP3 interacting protein 1



chr19_-_11688500 1.471 ENST00000433365.2
ACP5
acid phosphatase 5, tartrate resistant
chr17_-_34207295 1.451 ENST00000463941.1
ENST00000293272.3
CCL5

chemokine (C-C motif) ligand 5

chr16_+_50730910 1.398 ENST00000300589.2
NOD2
nucleotide-binding oligomerization domain containing 2
chr5_-_150460914 1.351 ENST00000389378.2
TNIP1
TNFAIP3 interacting protein 1
chr15_+_85923797 1.335 ENST00000559362.1
AKAP13
A kinase (PRKA) anchor protein 13
chr1_+_156123359 1.302 ENST00000368284.1
ENST00000368286.2
ENST00000438830.1
SEMA4A


sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A


chr3_-_4793274 1.296 ENST00000414938.1
EGOT
eosinophil granule ontogeny transcript (non-protein coding)
chr22_-_39268308 1.283 ENST00000407418.3
CBX6
chromobox homolog 6
chr19_+_45504688 1.282 ENST00000221452.8
ENST00000540120.1
ENST00000505236.1
RELB


v-rel avian reticuloendotheliosis viral oncogene homolog B


chr3_+_53195136 1.280 ENST00000394729.2
ENST00000330452.3
PRKCD

protein kinase C, delta

chr1_+_156123318 1.276 ENST00000368285.3
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr1_-_209825674 1.260 ENST00000367030.3
ENST00000356082.4
LAMB3

laminin, beta 3

chr2_+_61108771 1.215 ENST00000394479.3
REL
v-rel avian reticuloendotheliosis viral oncogene homolog
chr17_-_7590745 1.208 ENST00000514944.1
ENST00000503591.1
ENST00000455263.2
ENST00000420246.2
ENST00000445888.2
ENST00000509690.1
ENST00000604348.1
ENST00000269305.4
TP53







tumor protein p53







chr6_+_106534192 1.200 ENST00000369091.2
ENST00000369096.4
PRDM1

PR domain containing 1, with ZNF domain

chr6_+_135502466 1.141 ENST00000367814.4
MYB
v-myb avian myeloblastosis viral oncogene homolog
chr22_-_39268192 1.069 ENST00000216083.6
CBX6
chromobox homolog 6
chr8_+_38758737 1.059 ENST00000521746.1
ENST00000420274.1
PLEKHA2

pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2

chr5_-_150466692 1.052 ENST00000315050.7
ENST00000523338.1
ENST00000522100.1
TNIP1


TNFAIP3 interacting protein 1


chr16_+_50775948 1.016 ENST00000569681.1
ENST00000569418.1
ENST00000540145.1
CYLD


cylindromatosis (turban tumor syndrome)


chr3_+_57261743 0.994 ENST00000288266.3
APPL1
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
chr15_+_85923856 0.936 ENST00000560302.1
ENST00000394518.2
ENST00000361243.2
ENST00000560256.1
AKAP13



A kinase (PRKA) anchor protein 13



chr12_+_11802753 0.927 ENST00000396373.4
ETV6
ets variant 6
chr10_+_104154229 0.908 ENST00000428099.1
ENST00000369966.3
NFKB2

nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)

chr9_-_136344197 0.906 ENST00000414172.1
ENST00000371897.4
SLC2A6

solute carrier family 2 (facilitated glucose transporter), member 6

chr6_+_292051 0.884 ENST00000344450.5
DUSP22
dual specificity phosphatase 22
chrX_-_30595959 0.858 ENST00000378962.3
CXorf21
chromosome X open reading frame 21
chr1_-_205744574 0.807 ENST00000367139.3
ENST00000235932.4
ENST00000437324.2
ENST00000414729.1
RAB7L1



RAB7, member RAS oncogene family-like 1



chr1_+_26869597 0.792 ENST00000530003.1
RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr2_-_89442621 0.750 ENST00000492167.1
IGKV3-20
immunoglobulin kappa variable 3-20
chr14_+_103589789 0.718 ENST00000558056.1
ENST00000560869.1
TNFAIP2

tumor necrosis factor, alpha-induced protein 2

chr1_-_54304212 0.717 ENST00000540001.1
NDC1
NDC1 transmembrane nucleoporin
chr11_+_10476851 0.678 ENST00000396553.2
AMPD3
adenosine monophosphate deaminase 3
chr1_-_54303949 0.657 ENST00000234725.8
NDC1
NDC1 transmembrane nucleoporin
chr4_-_185395672 0.639 ENST00000393593.3
IRF2
interferon regulatory factor 2
chr19_+_10381769 0.630 ENST00000423829.2
ENST00000588645.1
ICAM1

intercellular adhesion molecule 1

chr6_+_87865262 0.619 ENST00000369577.3
ENST00000518845.1
ENST00000339907.4
ENST00000496806.2
ZNF292



zinc finger protein 292



chr11_-_72853091 0.618 ENST00000311172.7
ENST00000409314.1
FCHSD2

FCH and double SH3 domains 2

chr2_+_97203082 0.604 ENST00000454558.2
ARID5A
AT rich interactive domain 5A (MRF1-like)
chr1_-_202130702 0.604 ENST00000309017.3
ENST00000477554.1
ENST00000492451.1
PTPN7


protein tyrosine phosphatase, non-receptor type 7


chr1_-_54303934 0.582 ENST00000537333.1
NDC1
NDC1 transmembrane nucleoporin
chr1_-_236030216 0.577 ENST00000389794.3
ENST00000389793.2
LYST

lysosomal trafficking regulator

chr6_+_144471643 0.575 ENST00000367568.4
STX11
syntaxin 11
chr9_+_19230433 0.546 ENST00000434457.2
ENST00000602925.1
DENND4C

DENN/MADD domain containing 4C

chr1_+_46640750 0.544 ENST00000372003.1
TSPAN1
tetraspanin 1
chr1_+_63833261 0.532 ENST00000371108.4
ALG6
ALG6, alpha-1,3-glucosyltransferase
chr2_+_233925064 0.530 ENST00000359570.5
ENST00000538935.1
INPP5D

inositol polyphosphate-5-phosphatase, 145kDa

chr1_-_205744205 0.523 ENST00000446390.2
RAB7L1
RAB7, member RAS oncogene family-like 1
chr19_+_41281060 0.518 ENST00000594436.1
ENST00000597784.1
MIA

melanoma inhibitory activity

chr2_+_97202480 0.518 ENST00000357485.3
ARID5A
AT rich interactive domain 5A (MRF1-like)
chr17_-_4852332 0.516 ENST00000572383.1
PFN1
profilin 1
chr12_-_54653313 0.505 ENST00000550411.1
ENST00000439541.2
CBX5

chromobox homolog 5

chr17_+_16318909 0.505 ENST00000577397.1
TRPV2
transient receptor potential cation channel, subfamily V, member 2
chr2_+_208394616 0.501 ENST00000432329.2
ENST00000353267.3
ENST00000445803.1
CREB1


cAMP responsive element binding protein 1


chr11_-_3862206 0.497 ENST00000351018.4
RHOG
ras homolog family member G
chr1_+_101185290 0.486 ENST00000370119.4
ENST00000347652.2
ENST00000294728.2
ENST00000370115.1
VCAM1



vascular cell adhesion molecule 1



chr17_+_16318850 0.479 ENST00000338560.7
TRPV2
transient receptor potential cation channel, subfamily V, member 2
chr19_-_4831701 0.471 ENST00000248244.5
TICAM1
toll-like receptor adaptor molecule 1
chr5_+_150591678 0.470 ENST00000523466.1
GM2A
GM2 ganglioside activator
chr2_+_163175394 0.466 ENST00000446271.1
ENST00000429691.2
GCA

grancalcin, EF-hand calcium binding protein

chr1_-_65432171 0.462 ENST00000342505.4
JAK1
Janus kinase 1
chr12_+_49761273 0.458 ENST00000551540.1
ENST00000552918.1
ENST00000548777.1
ENST00000547865.1
ENST00000552171.1
SPATS2




spermatogenesis associated, serine-rich 2




chr19_-_51472031 0.449 ENST00000391808.1
KLK6
kallikrein-related peptidase 6
chr4_+_114214125 0.440 ENST00000509550.1
ANK2
ankyrin 2, neuronal
chr1_-_151319710 0.433 ENST00000290524.4
ENST00000437327.1
ENST00000452513.2
ENST00000368870.2
ENST00000452671.2
RFX5




regulatory factor X, 5 (influences HLA class II expression)




chr7_-_93520259 0.421 ENST00000222543.5
TFPI2
tissue factor pathway inhibitor 2
chr12_+_49761224 0.417 ENST00000553127.1
ENST00000321898.6
SPATS2

spermatogenesis associated, serine-rich 2

chr1_-_209824643 0.404 ENST00000391911.1
ENST00000415782.1
LAMB3

laminin, beta 3

chr7_-_93520191 0.398 ENST00000545378.1
TFPI2
tissue factor pathway inhibitor 2
chr15_+_57884086 0.395 ENST00000380569.2
ENST00000380561.2
ENST00000574161.1
ENST00000572390.1
ENST00000396180.1
ENST00000380560.2
GCOM1





GRINL1A complex locus 1





chr19_+_45251804 0.383 ENST00000164227.5
BCL3
B-cell CLL/lymphoma 3
chr4_-_174256276 0.372 ENST00000296503.5
HMGB2
high mobility group box 2
chr12_+_5019061 0.366 ENST00000382545.3
KCNA1
potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)
chr22_-_28315115 0.363 ENST00000455418.3
ENST00000436663.1
ENST00000320996.10
ENST00000335272.5
PITPNB



phosphatidylinositol transfer protein, beta



chr20_+_18488528 0.363 ENST00000377465.1
SEC23B
Sec23 homolog B (S. cerevisiae)
chr8_-_70747205 0.358 ENST00000260126.4
SLCO5A1
solute carrier organic anion transporter family, member 5A1
chr15_+_57884199 0.358 ENST00000587652.1
ENST00000380568.3
ENST00000380563.2
ENST00000380565.4
GCOM1

POLR2M
MYZAP
GRINL1A complex locus 1

polymerase (RNA) II (DNA directed) polypeptide M
myocardial zonula adherens protein
chr18_-_12884259 0.357 ENST00000353319.4
ENST00000327283.3
PTPN2

protein tyrosine phosphatase, non-receptor type 2

chr12_-_56727487 0.352 ENST00000548043.1
ENST00000425394.2
PAN2

PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)

chr12_-_28124903 0.350 ENST00000395872.1
ENST00000354417.3
ENST00000201015.4
PTHLH


parathyroid hormone-like hormone


chr10_+_12391685 0.341 ENST00000378845.1
CAMK1D
calcium/calmodulin-dependent protein kinase ID
chr3_-_49131473 0.337 ENST00000430979.1
ENST00000357496.2
ENST00000437939.1
QRICH1


glutamine-rich 1


chr2_+_208394658 0.330 ENST00000421139.1
CREB1
cAMP responsive element binding protein 1
chr5_+_133984462 0.328 ENST00000398844.2
ENST00000322887.4
SEC24A

SEC24 family member A

chr6_-_30712313 0.323 ENST00000376377.2
ENST00000259874.5
IER3

immediate early response 3

chr11_-_790060 0.322 ENST00000330106.4
CEND1
cell cycle exit and neuronal differentiation 1
chr4_-_151936416 0.314 ENST00000510413.1
ENST00000507224.1
LRBA

LPS-responsive vesicle trafficking, beach and anchor containing

chr1_-_209979375 0.305 ENST00000367021.3
IRF6
interferon regulatory factor 6
chr2_+_208394455 0.298 ENST00000430624.1
CREB1
cAMP responsive element binding protein 1
chr2_+_44396000 0.292 ENST00000409895.4
ENST00000409432.3
ENST00000282412.4
ENST00000378551.2
ENST00000345249.4
PPM1B




protein phosphatase, Mg2+/Mn2+ dependent, 1B




chr13_-_52027134 0.291 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
INTS6




integrator complex subunit 6




chr1_-_41950342 0.289 ENST00000372587.4
EDN2
endothelin 2
chr21_+_34775181 0.273 ENST00000290219.6
IFNGR2
interferon gamma receptor 2 (interferon gamma transducer 1)
chr5_+_140787600 0.268 ENST00000520790.1
PCDHGB6
protocadherin gamma subfamily B, 6
chr12_+_53662073 0.267 ENST00000553219.1
ENST00000257934.4
ESPL1

extra spindle pole bodies homolog 1 (S. cerevisiae)

chr12_-_49259643 0.266 ENST00000309739.5
RND1
Rho family GTPase 1
chr11_-_128392085 0.253 ENST00000526145.2
ENST00000531611.1
ENST00000319397.6
ENST00000345075.4
ENST00000535549.1
ETS1




v-ets avian erythroblastosis virus E26 oncogene homolog 1




chr1_-_202129105 0.250 ENST00000367279.4
PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr10_+_13141585 0.249 ENST00000378764.2
OPTN
optineurin
chr21_+_34775698 0.245 ENST00000381995.1
IFNGR2
interferon gamma receptor 2 (interferon gamma transducer 1)
chr9_+_82187630 0.242 ENST00000265284.6
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr12_-_56727676 0.241 ENST00000547572.1
ENST00000257931.5
ENST00000440411.3
PAN2


PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)


chr2_+_208394794 0.240 ENST00000536726.1
ENST00000374397.4
ENST00000452474.1
CREB1


cAMP responsive element binding protein 1


chr18_+_3252265 0.237 ENST00000580887.1
ENST00000536605.1
MYL12A

myosin, light chain 12A, regulatory, non-sarcomeric

chr4_+_140222609 0.236 ENST00000296543.5
ENST00000398947.1
NAA15

N(alpha)-acetyltransferase 15, NatA auxiliary subunit

chr20_+_18488137 0.234 ENST00000450074.1
ENST00000262544.2
ENST00000336714.3
ENST00000377475.3
SEC23B



Sec23 homolog B (S. cerevisiae)



chr9_+_82187487 0.220 ENST00000435650.1
ENST00000414465.1
ENST00000376537.4
ENST00000376534.4
TLE4



transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)



chr5_-_141257954 0.215 ENST00000456271.1
ENST00000394536.3
ENST00000503492.1
ENST00000287008.3
PCDH1



protocadherin 1



chr13_+_47127322 0.212 ENST00000389798.3
LRCH1
leucine-rich repeats and calponin homology (CH) domain containing 1
chr7_+_143013198 0.207 ENST00000343257.2
CLCN1
chloride channel, voltage-sensitive 1
chr11_-_6633799 0.204 ENST00000299424.4
TAF10
TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa
chr21_+_34775772 0.203 ENST00000405436.1
IFNGR2
interferon gamma receptor 2 (interferon gamma transducer 1)
chr9_+_36572851 0.201 ENST00000298048.2
ENST00000538311.1
ENST00000536987.1
ENST00000545008.1
ENST00000536860.1
ENST00000536329.1
ENST00000541717.1
ENST00000543751.1
MELK







maternal embryonic leucine zipper kinase







chr10_+_22605304 0.197 ENST00000456711.1
ENST00000444869.1
ENST00000475460.2
ENST00000602390.1
ENST00000489125.2
COMMD3

COMMD3-BMI1


COMM domain containing 3

COMMD3-BMI1 readthrough


chr11_-_66313699 0.190 ENST00000526986.1
ENST00000310442.3
ZDHHC24

zinc finger, DHHC-type containing 24

chr2_+_203776937 0.188 ENST00000402905.3
ENST00000414490.1
ENST00000431787.1
ENST00000444724.1
ENST00000414857.1
ENST00000430899.1
ENST00000445120.1
ENST00000441569.1
ENST00000432024.1
ENST00000443740.1
ENST00000414439.1
ENST00000428585.1
ENST00000545253.1
ENST00000545262.1
ENST00000447539.1
ENST00000456821.2
ENST00000434998.1
ENST00000320443.8
CARF

















calcium responsive transcription factor

















chr19_-_51471362 0.178 ENST00000376853.4
ENST00000424910.2
KLK6

kallikrein-related peptidase 6

chr10_+_22605374 0.172 ENST00000448361.1
COMMD3
COMM domain containing 3
chr4_+_74735102 0.171 ENST00000395761.3
CXCL1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr7_-_16844611 0.166 ENST00000401412.1
ENST00000419304.2
AGR2

anterior gradient 2

chr12_+_53662110 0.163 ENST00000552462.1
ESPL1
extra spindle pole bodies homolog 1 (S. cerevisiae)
chr14_+_22984601 0.153 ENST00000390509.1
TRAJ28
T cell receptor alpha joining 28
chr6_-_136847099 0.151 ENST00000438100.2
MAP7
microtubule-associated protein 7
chr1_-_202129704 0.151 ENST00000476061.1
ENST00000544762.1
ENST00000467283.1
ENST00000464870.1
ENST00000435759.2
ENST00000486116.1
ENST00000543735.1
ENST00000308986.5
ENST00000477625.1
PTPN7








protein tyrosine phosphatase, non-receptor type 7








chr2_-_136743039 0.147 ENST00000537273.1
DARS
aspartyl-tRNA synthetase
chr3_+_5163905 0.141 ENST00000256496.3
ENST00000419534.2
ARL8B

ADP-ribosylation factor-like 8B

chr10_+_74870253 0.141 ENST00000544879.1
ENST00000537969.1
ENST00000372997.3
NUDT13


nudix (nucleoside diphosphate linked moiety X)-type motif 13


chr15_-_71055878 0.139 ENST00000322954.6
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr6_-_30710510 0.132 ENST00000376389.3
FLOT1
flotillin 1
chr22_+_41347363 0.127 ENST00000216225.8
RBX1
ring-box 1, E3 ubiquitin protein ligase
chr14_+_24439148 0.124 ENST00000543805.1
ENST00000534993.1
DHRS4L2

dehydrogenase/reductase (SDR family) member 4 like 2

chr10_+_74870206 0.124 ENST00000357321.4
ENST00000349051.5
NUDT13

nudix (nucleoside diphosphate linked moiety X)-type motif 13

chr11_-_44331679 0.123 ENST00000329255.3
ALX4
ALX homeobox 4
chr1_-_1822495 0.121 ENST00000378609.4
GNB1
guanine nucleotide binding protein (G protein), beta polypeptide 1
chr1_-_155658085 0.120 ENST00000311573.5
ENST00000438245.2
YY1AP1

YY1 associated protein 1

chr19_-_51471381 0.117 ENST00000594641.1
KLK6
kallikrein-related peptidase 6
chr9_+_82188077 0.109 ENST00000425506.1
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr16_+_67282853 0.108 ENST00000299798.11
SLC9A5
solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
chr12_-_57504069 0.098 ENST00000543873.2
ENST00000554663.1
ENST00000557635.1
STAT6


signal transducer and activator of transcription 6, interleukin-4 induced


chr5_+_112312416 0.094 ENST00000389063.2
DCP2
decapping mRNA 2
chr3_+_141205852 0.091 ENST00000286364.3
ENST00000452898.1
RASA2

RAS p21 protein activator 2

chr1_-_203274418 0.090 ENST00000457348.1
RP11-134P9.1
long intergenic non-protein coding RNA 1136
chr11_+_18287801 0.088 ENST00000532858.1
ENST00000405158.2
SAA1

serum amyloid A1

chr18_-_31802282 0.087 ENST00000535475.1
NOL4
nucleolar protein 4
chr2_+_162016916 0.086 ENST00000405852.1
TANK
TRAF family member-associated NFKB activator
chr11_+_65190245 0.082 ENST00000499732.1
ENST00000501122.2
ENST00000601801.1
NEAT1


nuclear paraspeckle assembly transcript 1 (non-protein coding)



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 6.1 GO:0034135 regulation of toll-like receptor 2 signaling pathway(GO:0034135)
2.0 5.9 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.9 5.4 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.8 3.3 GO:1904037 positive regulation of epithelial cell apoptotic process(GO:1904037) positive regulation of endothelial cell apoptotic process(GO:2000353)
0.8 4.9 GO:0060263 regulation of respiratory burst(GO:0060263)
0.8 3.2 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.8 3.8 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.7 2.8 GO:0002268 follicular dendritic cell activation(GO:0002266) follicular dendritic cell differentiation(GO:0002268)
0.7 2.1 GO:0002678 positive regulation of chronic inflammatory response(GO:0002678) regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.7 2.7 GO:0050965 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.6 1.2 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.6 5.1 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.5 11.5 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.5 2.6 GO:0010957 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.5 1.9 GO:0070842 aggresome assembly(GO:0070842)
0.4 1.7 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.3 3.6 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.3 4.7 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.3 2.6 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.2 1.7 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.2 0.5 GO:0045350 interferon-beta biosynthetic process(GO:0045350) regulation of interferon-beta biosynthetic process(GO:0045357) positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.2 1.4 GO:0032916 transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910) positive regulation of transforming growth factor beta3 production(GO:0032916)
0.2 5.7 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.2 4.1 GO:0045885 obsolete positive regulation of survival gene product expression(GO:0045885)
0.2 0.6 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.2 6.0 GO:0060334 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.2 0.6 GO:0033364 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510) mast cell secretory granule organization(GO:0033364)
0.2 1.3 GO:0043011 myeloid dendritic cell differentiation(GO:0043011) dendritic cell differentiation(GO:0097028)
0.2 0.5 GO:0045656 negative regulation of monocyte differentiation(GO:0045656)
0.1 0.3 GO:0060585 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.1 10.7 GO:0051291 protein heterooligomerization(GO:0051291)
0.1 0.7 GO:0006196 AMP catabolic process(GO:0006196)
0.1 0.4 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.1 3.6 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.1 0.5 GO:0022614 membrane to membrane docking(GO:0022614)
0.1 1.0 GO:0032613 interleukin-10 production(GO:0032613)
0.1 0.3 GO:0060649 nipple development(GO:0060618) mammary gland bud elongation(GO:0060649) nipple morphogenesis(GO:0060658) nipple sheath formation(GO:0060659)
0.1 0.3 GO:0090161 Golgi ribbon formation(GO:0090161)
0.1 0.5 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.1 2.1 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.1 0.4 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.1 0.8 GO:0016540 protein autoprocessing(GO:0016540)
0.1 1.2 GO:0001893 maternal placenta development(GO:0001893)
0.1 1.7 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 1.5 GO:0090003 regulation of establishment of protein localization to plasma membrane(GO:0090003) regulation of protein localization to plasma membrane(GO:1903076) regulation of protein localization to cell periphery(GO:1904375)
0.1 0.3 GO:0030578 nuclear body organization(GO:0030575) PML body organization(GO:0030578)
0.0 2.4 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.2 GO:0070254 mucus secretion(GO:0070254)
0.0 0.1 GO:0048295 positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.0 3.4 GO:0007605 sensory perception of sound(GO:0007605)
0.0 0.3 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.2 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.3 GO:0016180 snRNA processing(GO:0016180)
0.0 0.2 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 1.5 GO:0006968 cellular defense response(GO:0006968)
0.0 0.3 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)
0.0 0.3 GO:0060644 mammary gland epithelial cell differentiation(GO:0060644)
0.0 0.1 GO:0045116 protein neddylation(GO:0045116)
0.0 0.5 GO:0006490 dolichol-linked oligosaccharide biosynthetic process(GO:0006488) oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.0 2.8 GO:0006333 chromatin assembly or disassembly(GO:0006333)
0.0 1.4 GO:0030168 platelet activation(GO:0030168)
0.0 0.7 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 1.0 GO:0061025 membrane fusion(GO:0061025)
0.0 0.6 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.0 0.2 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.5 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 1.0 GO:0009408 response to heat(GO:0009408)
0.0 0.4 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 0.1 GO:0060526 prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 9.2 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.8 17.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.6 3.6 GO:0019815 immunoglobulin complex(GO:0019814) B cell receptor complex(GO:0019815)
0.6 1.7 GO:0005610 laminin-5 complex(GO:0005610)
0.4 2.2 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.3 4.6 GO:0035631 CD40 receptor complex(GO:0035631)
0.2 5.7 GO:0042612 MHC protein complex(GO:0042611) MHC class I protein complex(GO:0042612)
0.2 4.9 GO:0000299 obsolete integral to membrane of membrane fraction(GO:0000299)
0.2 0.5 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.1 0.5 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.1 1.9 GO:0016235 aggresome(GO:0016235)
0.1 4.7 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 1.4 GO:0008180 COP9 signalosome(GO:0008180)
0.1 0.5 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.1 0.9 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 10.6 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 1.4 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.1 9.5 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.9 GO:0090568 NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)
0.0 0.1 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 0.4 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.1 GO:0051233 spindle midzone(GO:0051233)
0.0 1.1 GO:0016363 nuclear matrix(GO:0016363)
0.0 3.2 GO:0005813 centrosome(GO:0005813)
0.0 1.1 GO:0000790 nuclear chromatin(GO:0000790)
0.0 0.3 GO:0005802 trans-Golgi network(GO:0005802)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 5.9 GO:0042289 MHC class II protein binding(GO:0042289)
1.5 4.4 GO:0019976 interleukin-2 binding(GO:0019976)
0.8 11.5 GO:0032395 MHC class II receptor activity(GO:0032395)
0.4 5.7 GO:0032393 MHC class I receptor activity(GO:0032393)
0.4 1.5 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.3 3.6 GO:0004568 chitinase activity(GO:0004568)
0.3 9.2 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.3 1.2 GO:0000739 obsolete DNA strand annealing activity(GO:0000739)
0.3 1.7 GO:0019863 IgE binding(GO:0019863)
0.2 5.2 GO:0070064 proline-rich region binding(GO:0070064)
0.2 3.8 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.2 3.2 GO:0008199 acid phosphatase activity(GO:0003993) ferric iron binding(GO:0008199)
0.2 4.7 GO:0043621 protein self-association(GO:0043621)
0.2 1.4 GO:0050700 CARD domain binding(GO:0050700)
0.2 0.6 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.2 0.5 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.2 2.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.7 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.1 1.0 GO:0043422 protein kinase B binding(GO:0043422)
0.1 1.9 GO:0070628 proteasome binding(GO:0070628)
0.1 2.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.9 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.1 2.2 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 2.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 2.8 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 1.1 GO:0043236 laminin binding(GO:0043236)
0.1 0.7 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.5 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 0.9 GO:0016565 obsolete general transcriptional repressor activity(GO:0016565)
0.1 1.3 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.1 0.3 GO:0031708 bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0 0.5 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 8.0 GO:0003702 obsolete RNA polymerase II transcription factor activity(GO:0003702)
0.0 1.9 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 0.5 GO:0046527 glucosyltransferase activity(GO:0046527)
0.0 9.9 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.8 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.6 GO:0043498 obsolete cell surface binding(GO:0043498)
0.0 0.1 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 1.1 GO:0016566 obsolete specific transcriptional repressor activity(GO:0016566)
0.0 0.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 1.4 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.2 GO:0016896 exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896)
0.0 3.2 GO:0003924 GTPase activity(GO:0003924)
0.0 0.1 GO:0015385 sodium:proton antiporter activity(GO:0015385)
0.0 1.4 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 2.2 GO:0003682 chromatin binding(GO:0003682)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 23.5 ST_TUMOR_NECROSIS_FACTOR_PATHWAY Tumor Necrosis Factor Pathway.
0.2 2.8 ST_INTERFERON_GAMMA_PATHWAY Interferon gamma pathway.
0.1 5.4 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.2 SA_G1_AND_S_PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.5 ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY PI3K Pathway