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Motif ID: RFX5

Z-value: 2.084

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr6_-_32557610	9.727	ENST00000360004.5	HLA-DRB1	major histocompatibility complex, class II, DR beta 1
chr6_-_32498046	8.990	ENST00000374975.3	HLA-DRB5	major histocompatibility complex, class II, DR beta 5
chr5_-_149792295	8.279	ENST00000518797.1 ENST00000524315.1 ENST00000009530.7 ENST00000377795.3	CD74	CD74 molecule, major histocompatibility complex, class II invariant chain
chr6_+_33043703	8.207	ENST00000418931.2 ENST00000535465.1	HLA-DPB1	major histocompatibility complex, class II, DP beta 1
chr6_-_32920794	7.437	ENST00000395305.3 ENST00000395303.3 ENST00000374843.4 ENST00000429234.1	HLA-DMA XXbac-BPG181M17.5	major histocompatibility complex, class II, DM alpha Uncharacterized protein
chr6_-_32908792	6.435	ENST00000418107.2	HLA-DMB	major histocompatibility complex, class II, DM beta
chr6_-_32634425	5.747	ENST00000399082.3 ENST00000399079.3 ENST00000374943.4 ENST00000434651.2	HLA-DQB1	major histocompatibility complex, class II, DQ beta 1
chr6_+_32821924	4.770	ENST00000374859.2 ENST00000453265.2	PSMB9	proteasome (prosome, macropain) subunit, beta type, 9
chr6_-_32784687	4.502	ENST00000447394.1 ENST00000438763.2	HLA-DOB	major histocompatibility complex, class II, DO beta
chr6_+_32812568	4.063	ENST00000414474.1	PSMB9	proteasome (prosome, macropain) subunit, beta type, 9
chr6_-_32812420	3.793	ENST00000374881.2	PSMB8	proteasome (prosome, macropain) subunit, beta type, 8
chr6_-_32731299	3.212	ENST00000435145.2 ENST00000437316.2	HLA-DQB2	major histocompatibility complex, class II, DQ beta 2
chr13_-_47012325	3.074	ENST00000409879.2	KIAA0226L	KIAA0226-like
chr6_-_32821599	2.880	ENST00000354258.4	TAP1	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr2_-_242088850	2.683	ENST00000358649.4 ENST00000452907.1 ENST00000403638.3 ENST00000539818.1 ENST00000415234.1 ENST00000234040.4	PASK	PAS domain containing serine/threonine kinase
chr6_-_32908765	2.598	ENST00000416244.2	HLA-DMB	major histocompatibility complex, class II, DM beta
chr1_+_181003067	1.608	ENST00000434571.2 ENST00000367579.3 ENST00000282990.6 ENST00000367580.5	MR1	major histocompatibility complex, class I-related
chr6_-_32731243	1.505	ENST00000427449.1 ENST00000411527.1	HLA-DQB2	major histocompatibility complex, class II, DQ beta 2
chr6_+_26383404	1.366	ENST00000416795.2 ENST00000494184.1	BTN2A2	butyrophilin, subfamily 2, member A2
chr6_+_26383318	1.295	ENST00000469230.1 ENST00000490025.1 ENST00000356709.4 ENST00000352867.2 ENST00000493275.1 ENST00000472507.1 ENST00000482536.1 ENST00000432533.2 ENST00000482842.1	BTN2A2	butyrophilin, subfamily 2, member A2
chr1_+_249132462	1.271	ENST00000306562.3	ZNF672	zinc finger protein 672
chr6_-_133079022	0.960	ENST00000525289.1 ENST00000326499.6	VNN2	vanin 2
chr19_+_36103631	0.905	ENST00000203166.5 ENST00000379045.2	HAUS5	HAUS augmin-like complex, subunit 5
chr16_+_67381263	0.843	ENST00000541146.1 ENST00000563189.1 ENST00000290940.7	LRRC36	leucine rich repeat containing 36
chr6_+_26440700	0.834	ENST00000494393.1 ENST00000482451.1 ENST00000244519.2 ENST00000339789.4 ENST00000471353.1 ENST00000361232.3 ENST00000487627.1 ENST00000496719.1 ENST00000490254.1 ENST00000487272.1	BTN3A3	butyrophilin, subfamily 3, member A3
chr8_-_98290087	0.829	ENST00000322128.3	TSPYL5	TSPY-like 5
chr16_+_67381289	0.790	ENST00000435835.3	LRRC36	leucine rich repeat containing 36
chr16_-_74808710	0.782	ENST00000219368.3 ENST00000544337.1	FA2H	fatty acid 2-hydroxylase
chr2_+_242089046	0.651	ENST00000407025.1 ENST00000272983.8	PPP1R7	protein phosphatase 1, regulatory subunit 7
chr2_+_242088963	0.561	ENST00000438799.1 ENST00000402734.1 ENST00000423280.1	PPP1R7	protein phosphatase 1, regulatory subunit 7
chr8_+_101170257	0.444	ENST00000251809.3	SPAG1	sperm associated antigen 1
chr6_+_26365443	0.398	ENST00000527422.1 ENST00000356386.2 ENST00000396934.3 ENST00000377708.2 ENST00000396948.1 ENST00000508906.2	BTN3A2	butyrophilin, subfamily 3, member A2
chr4_-_83719884	0.365	ENST00000282709.4 ENST00000273908.4	SCD5	stearoyl-CoA desaturase 5
chr20_+_42875935	0.338	ENST00000438466.1 ENST00000372952.3 ENST00000537864.1 ENST00000445952.1	GDAP1L1	ganglioside induced differentiation associated protein 1-like 1
chr20_+_42875887	0.301	ENST00000342560.5	GDAP1L1	ganglioside induced differentiation associated protein 1-like 1
chr6_-_24666819	0.264	ENST00000341060.3	TDP2	tyrosyl-DNA phosphodiesterase 2
chr2_+_173600565	0.261	ENST00000397081.3	RAPGEF4	Rap guanine nucleotide exchange factor (GEF) 4
chr2_+_173600514	0.258	ENST00000264111.6	RAPGEF4	Rap guanine nucleotide exchange factor (GEF) 4
chr6_-_24667180	0.104	ENST00000545995.1	TDP2	tyrosyl-DNA phosphodiesterase 2
chr8_-_99306611	0.092	ENST00000341166.3	NIPAL2	NIPA-like domain containing 2
chr3_+_196466710	0.085	ENST00000327134.3	PAK2	p21 protein (Cdc42/Rac)-activated kinase 2
chr8_-_99306564	0.053	ENST00000430223.2	NIPAL2	NIPA-like domain containing 2
chr6_-_30181133	0.046	ENST00000454678.2 ENST00000434785.1	TRIM26	tripartite motif containing 26
chr1_+_36549676	0.045	ENST00000207457.3	TEKT2	tektin 2 (testicular)
chr6_-_30181156	0.010	ENST00000418026.1 ENST00000416596.1 ENST00000453195.1	TRIM26	tripartite motif containing 26

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.8	8.3	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
2.7	58.4	GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.7	2.9	GO:0046967	cytosol to ER transport(GO:0046967)
0.1	11.4	GO:0006521	regulation of cellular amino acid metabolic process(GO:0006521)
0.1	0.8	GO:0071480	cellular response to gamma radiation(GO:0071480)
0.1	1.0	GO:0015939	pantothenate metabolic process(GO:0015939)
0.0	0.7	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0	0.9	GO:0051225	spindle assembly(GO:0051225)
0.0	0.5	GO:0019933	cAMP-mediated signaling(GO:0019933)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.2	66.6	GO:0042613	MHC class II protein complex(GO:0042613)
0.4	2.9	GO:0042825	TAP complex(GO:0042825)
0.4	12.6	GO:0005839	proteasome core complex(GO:0005839)
0.1	0.9	GO:0070652	HAUS complex(GO:0070652)
0.0	0.7	GO:0042611	MHC protein complex(GO:0042611)
0.0	0.5	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.8	8.3	GO:0042289	MHC class II protein binding(GO:0042289)
1.8	24.7	GO:0032395	MHC class II receptor activity(GO:0032395)
0.6	2.9	GO:0046980	oligopeptide-transporting ATPase activity(GO:0015421) tapasin binding(GO:0046980)
0.4	12.6	GO:0004298	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.2	1.2	GO:0008599	protein phosphatase type 1 regulator activity(GO:0008599)
0.2	1.0	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.1	0.4	GO:0070260	5'-tyrosyl-DNA phosphodiesterase activity(GO:0070260)
0.1	0.4	GO:0004768	stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.1	1.6	GO:0032393	MHC class I receptor activity(GO:0032393)
0.0	0.5	GO:0030552	cAMP binding(GO:0030552)

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