Motif ID: RUNX1_RUNX2

Z-value: 2.996

Transcription factors associated with RUNX1_RUNX2:

Gene SymbolEntrez IDGene Name
RUNX1 ENSG00000159216.14 RUNX1
RUNX2 ENSG00000124813.16 RUNX2






Network of associatons between targets according to the STRING database.



First level regulatory network of RUNX1_RUNX2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr22_+_23241661 6.107 ENST00000390322.2
IGLJ2
immunoglobulin lambda joining 2
chr4_-_84035868 6.036 ENST00000426923.2
ENST00000509973.1
PLAC8

placenta-specific 8

chr4_-_84035905 5.954 ENST00000311507.4
PLAC8
placenta-specific 8
chr17_-_29641104 5.031 ENST00000577894.1
ENST00000330927.4
EVI2B

ecotropic viral integration site 2B

chr16_+_85942594 4.886 ENST00000566369.1
IRF8
interferon regulatory factor 8
chr17_-_29641084 4.737 ENST00000544462.1
EVI2B
ecotropic viral integration site 2B
chr11_+_7626950 4.280 ENST00000530181.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr17_-_34417479 3.995 ENST00000225245.5
CCL3
chemokine (C-C motif) ligand 3
chr22_+_23247030 3.738 ENST00000390324.2
IGLJ3
immunoglobulin lambda joining 3
chr2_-_158300556 3.523 ENST00000264192.3
CYTIP
cytohesin 1 interacting protein
chr8_-_102803163 3.346 ENST00000523645.1
ENST00000520346.1
ENST00000220931.6
ENST00000522448.1
ENST00000522951.1
ENST00000522252.1
ENST00000519098.1
NCALD






neurocalcin delta






chr6_+_31982539 3.014 ENST00000435363.2
ENST00000425700.2
C4B

complement component 4B (Chido blood group)

chr1_-_25291475 2.943 ENST00000338888.3
ENST00000399916.1
RUNX3

runt-related transcription factor 3

chr6_+_31949801 2.914 ENST00000428956.2
ENST00000498271.1
C4A

complement component 4A (Rodgers blood group)

chr1_+_209929377 2.875 ENST00000400959.3
ENST00000367025.3
TRAF3IP3

TRAF3 interacting protein 3

chr1_-_173174681 2.875 ENST00000367718.1
TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr12_-_53594227 2.860 ENST00000550743.2
ITGB7
integrin, beta 7
chr17_-_34524157 2.826 ENST00000378354.4
ENST00000394484.1
CCL3L3

chemokine (C-C motif) ligand 3-like 3

chr9_-_116840728 2.786 ENST00000265132.3
AMBP
alpha-1-microglobulin/bikunin precursor
chr1_+_198608146 2.691 ENST00000367376.2
ENST00000352140.3
ENST00000594404.1
ENST00000598951.1
ENST00000530727.1
ENST00000442510.2
ENST00000367367.4
ENST00000348564.6
ENST00000367364.1
ENST00000413409.2
PTPRC









protein tyrosine phosphatase, receptor type, C









chr17_-_34625719 2.680 ENST00000422211.2
ENST00000542124.1
CCL3L1

chemokine (C-C motif) ligand 3-like 1

chr16_+_23847339 2.654 ENST00000303531.7
PRKCB
protein kinase C, beta
chr11_+_121447469 2.632 ENST00000532694.1
ENST00000534286.1
SORL1

sortilin-related receptor, L(DLR class) A repeats containing

chr1_-_114414316 2.568 ENST00000528414.1
ENST00000538253.1
ENST00000460620.1
ENST00000420377.2
ENST00000525799.1
ENST00000359785.5
PTPN22





protein tyrosine phosphatase, non-receptor type 22 (lymphoid)





chr6_+_31543334 2.529 ENST00000449264.2
TNF
tumor necrosis factor
chrX_-_70838306 2.518 ENST00000373691.4
ENST00000373693.3
CXCR3

chemokine (C-X-C motif) receptor 3

chr4_+_88896819 2.471 ENST00000237623.7
ENST00000395080.3
ENST00000508233.1
ENST00000360804.4
SPP1



secreted phosphoprotein 1



chr1_+_192544857 2.398 ENST00000367459.3
ENST00000469578.2
RGS1

regulator of G-protein signaling 1

chr17_-_79008373 2.374 ENST00000577066.1
ENST00000573167.1
BAIAP2-AS1

BAIAP2 antisense RNA 1 (head to head)

chr12_+_25205568 2.299 ENST00000548766.1
ENST00000556887.1
LRMP

lymphoid-restricted membrane protein

chr19_-_6720686 2.298 ENST00000245907.6
C3
complement component 3
chr3_+_113251143 2.292 ENST00000264852.4
ENST00000393830.3
SIDT1

SID1 transmembrane family, member 1

chr12_+_25205446 2.208 ENST00000557489.1
ENST00000354454.3
ENST00000536173.1
LRMP


lymphoid-restricted membrane protein


chr11_+_22696314 2.200 ENST00000532398.1
ENST00000433790.1
GAS2

growth arrest-specific 2

chr16_+_23847267 2.199 ENST00000321728.7
PRKCB
protein kinase C, beta
chr14_-_106092403 2.185 ENST00000390543.2
IGHG4
immunoglobulin heavy constant gamma 4 (G4m marker)
chr2_+_90077680 2.164 ENST00000390270.2
IGKV3D-20
immunoglobulin kappa variable 3D-20
chr6_-_33048483 2.140 ENST00000419277.1
HLA-DPA1
major histocompatibility complex, class II, DP alpha 1
chr16_+_30194916 2.123 ENST00000570045.1
ENST00000565497.1
ENST00000570244.1
CORO1A


coronin, actin binding protein, 1A


chr16_+_72088376 2.065 ENST00000570083.1
ENST00000355906.5
ENST00000398131.2
ENST00000569639.1
ENST00000564499.1
ENST00000357763.4
ENST00000562526.1
ENST00000565574.1
ENST00000568417.2
ENST00000356967.5
HP








HPR
haptoglobin








haptoglobin-related protein
chr19_-_36233332 2.057 ENST00000592537.1
ENST00000246532.1
ENST00000344990.3
ENST00000588992.1
IGFLR1



IGF-like family receptor 1



chr13_-_46756351 2.049 ENST00000323076.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr19_-_41256207 2.013 ENST00000598485.2
ENST00000470681.1
ENST00000339153.3
ENST00000598729.1
C19orf54



chromosome 19 open reading frame 54



chr6_+_32407619 1.972 ENST00000395388.2
ENST00000374982.5
HLA-DRA

major histocompatibility complex, class II, DR alpha

chr2_+_68592305 1.954 ENST00000234313.7
PLEK
pleckstrin
chr10_+_114135004 1.931 ENST00000393081.1
ACSL5
acyl-CoA synthetase long-chain family member 5
chr2_+_8822113 1.928 ENST00000396290.1
ENST00000331129.3
ID2

inhibitor of DNA binding 2, dominant negative helix-loop-helix protein

chr1_+_209929494 1.903 ENST00000367026.3
TRAF3IP3
TRAF3 interacting protein 3
chr12_+_7055631 1.896 ENST00000543115.1
ENST00000399448.1
PTPN6

protein tyrosine phosphatase, non-receptor type 6

chr5_+_75699149 1.880 ENST00000379730.3
IQGAP2
IQ motif containing GTPase activating protein 2
chr17_-_62009621 1.877 ENST00000349817.2
ENST00000392795.3
CD79B

CD79b molecule, immunoglobulin-associated beta

chr5_-_138725594 1.814 ENST00000302125.8
MZB1
marginal zone B and B1 cell-specific protein
chr5_-_138725560 1.810 ENST00000412103.2
ENST00000457570.2
MZB1

marginal zone B and B1 cell-specific protein

chr6_-_11382478 1.800 ENST00000397378.3
ENST00000513989.1
ENST00000508546.1
ENST00000504387.1
NEDD9



neural precursor cell expressed, developmentally down-regulated 9



chr2_+_127413704 1.786 ENST00000409836.3
GYPC
glycophorin C (Gerbich blood group)
chr1_+_111772314 1.763 ENST00000466741.1
ENST00000477185.2
CHI3L2

chitinase 3-like 2

chr3_-_105588231 1.746 ENST00000545639.1
ENST00000394027.3
ENST00000438603.1
ENST00000447441.1
ENST00000443752.1
CBLB




Cbl proto-oncogene B, E3 ubiquitin protein ligase




chr6_+_32709119 1.719 ENST00000374940.3
HLA-DQA2
major histocompatibility complex, class II, DQ alpha 2
chr17_+_79935418 1.699 ENST00000306729.7
ENST00000306739.4
ASPSCR1

alveolar soft part sarcoma chromosome region, candidate 1

chr6_-_32920794 1.668 ENST00000395305.3
ENST00000395303.3
ENST00000374843.4
ENST00000429234.1
HLA-DMA


XXbac-BPG181M17.5
major histocompatibility complex, class II, DM alpha


Uncharacterized protein
chr16_+_85645007 1.667 ENST00000405402.2
GSE1
Gse1 coiled-coil protein
chr22_-_43411106 1.665 ENST00000453643.1
ENST00000263246.3
ENST00000337959.4
PACSIN2


protein kinase C and casein kinase substrate in neurons 2


chrX_-_2418936 1.652 ENST00000412516.2
ENST00000334651.5
ENST00000461691.1
ENST00000381223.4
ENST00000381222.2
DHRSX

ZBED1


dehydrogenase/reductase (SDR family) X-linked

zinc finger, BED-type containing 1


chr2_-_21266935 1.635 ENST00000233242.1
APOB
apolipoprotein B
chr22_+_22988816 1.629 ENST00000480559.1
ENST00000448514.1
GGTLC2

gamma-glutamyltransferase light chain 2

chr17_+_79935464 1.614 ENST00000581647.1
ENST00000580534.1
ENST00000579684.1
ASPSCR1


alveolar soft part sarcoma chromosome region, candidate 1


chr3_+_186330712 1.613 ENST00000411641.2
ENST00000273784.5
AHSG

alpha-2-HS-glycoprotein

chr4_-_38806404 1.601 ENST00000308979.2
ENST00000505940.1
ENST00000515861.1
TLR1


toll-like receptor 1


chr22_+_25003626 1.598 ENST00000451366.1
ENST00000406383.2
ENST00000428855.1
GGT1


gamma-glutamyltransferase 1


chr1_+_111415757 1.597 ENST00000429072.2
ENST00000271324.5
CD53

CD53 molecule

chr11_+_1874200 1.595 ENST00000311604.3
LSP1
lymphocyte-specific protein 1
chr16_+_27438563 1.587 ENST00000395754.4
IL21R
interleukin 21 receptor
chr17_-_10017864 1.579 ENST00000323816.4
GAS7
growth arrest-specific 7
chr13_-_99959641 1.560 ENST00000376414.4
GPR183
G protein-coupled receptor 183
chr3_-_98241358 1.559 ENST00000503004.1
ENST00000506575.1
ENST00000513452.1
ENST00000515620.1
CLDND1



claudin domain containing 1



chr14_+_75988851 1.548 ENST00000555504.1
BATF
basic leucine zipper transcription factor, ATF-like
chr17_-_40835076 1.541 ENST00000591765.1
CCR10
chemokine (C-C motif) receptor 10
chr5_+_75699040 1.531 ENST00000274364.6
IQGAP2
IQ motif containing GTPase activating protein 2
chrX_-_70331298 1.497 ENST00000456850.2
ENST00000473378.1
ENST00000487883.1
ENST00000374202.2
IL2RG



interleukin 2 receptor, gamma



chr8_+_11351876 1.489 ENST00000529894.1
BLK
B lymphoid tyrosine kinase
chr1_+_111772435 1.469 ENST00000524472.1
CHI3L2
chitinase 3-like 2
chr16_+_56965960 1.456 ENST00000439977.2
ENST00000344114.4
ENST00000300302.5
ENST00000379792.2
HERPUD1



homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1



chr7_+_116660246 1.436 ENST00000434836.1
ENST00000393443.1
ENST00000465133.1
ENST00000477742.1
ENST00000393447.4
ENST00000393444.3
ST7





suppression of tumorigenicity 7





chr4_-_71532339 1.435 ENST00000254801.4
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr4_+_74269956 1.427 ENST00000295897.4
ENST00000415165.2
ENST00000503124.1
ENST00000509063.1
ENST00000401494.3
ALB




albumin




chr13_-_46964177 1.427 ENST00000389908.3
KIAA0226L
KIAA0226-like
chr7_+_134832808 1.426 ENST00000275767.3
TMEM140
transmembrane protein 140
chr6_-_137540477 1.416 ENST00000367735.2
ENST00000367739.4
ENST00000458076.1
ENST00000414770.1
IFNGR1



interferon gamma receptor 1



chr21_-_46348694 1.408 ENST00000355153.4
ENST00000397850.2
ITGB2

integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)

chr15_-_72668185 1.403 ENST00000457859.2
ENST00000566304.1
ENST00000567159.1
ENST00000429918.2
HEXA



hexosaminidase A (alpha polypeptide)



chr17_-_62009702 1.399 ENST00000006750.3
CD79B
CD79b molecule, immunoglobulin-associated beta
chr22_-_21580582 1.390 ENST00000424627.1
GGT2
gamma-glutamyltransferase 2
chr16_-_28608364 1.388 ENST00000533150.1
SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr3_-_170744498 1.376 ENST00000382808.4
ENST00000314251.3
SLC2A2

solute carrier family 2 (facilitated glucose transporter), member 2

chr17_-_26695013 1.374 ENST00000555059.2
CTB-96E2.2
Homeobox protein SEBOX
chr11_-_2162468 1.365 ENST00000434045.2
IGF2
insulin-like growth factor 2 (somatomedin A)
chr21_+_42733870 1.361 ENST00000330714.3
ENST00000436410.1
ENST00000435611.1
MX2


myxovirus (influenza virus) resistance 2 (mouse)


chr20_-_23967432 1.358 ENST00000286890.4
ENST00000278765.4
GGTLC1

gamma-glutamyltransferase light chain 1

chr22_+_23264766 1.357 ENST00000390331.2
IGLC7
immunoglobulin lambda constant 7
chr8_+_11351494 1.352 ENST00000259089.4
BLK
B lymphoid tyrosine kinase
chr17_-_26694979 1.332 ENST00000438614.1
VTN
vitronectin
chr6_-_41168920 1.331 ENST00000483722.1
TREML2
triggering receptor expressed on myeloid cells-like 2
chrX_+_48542168 1.314 ENST00000376701.4
WAS
Wiskott-Aldrich syndrome
chr15_-_72668805 1.290 ENST00000268097.5
HEXA
hexosaminidase A (alpha polypeptide)
chrX_+_84258832 1.263 ENST00000373173.2
APOOL
apolipoprotein O-like
chr14_-_106573756 1.253 ENST00000390601.2
IGHV3-11
immunoglobulin heavy variable 3-11 (gene/pseudogene)
chr17_-_7017559 1.249 ENST00000446679.2
ASGR2
asialoglycoprotein receptor 2
chr19_+_1067492 1.242 ENST00000586866.1
HMHA1
histocompatibility (minor) HA-1
chr17_-_40833858 1.240 ENST00000332438.4
CCR10
chemokine (C-C motif) receptor 10
chr1_-_9129735 1.228 ENST00000377424.4
SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr20_+_61299155 1.214 ENST00000451793.1
SLCO4A1
solute carrier organic anion transporter family, member 4A1
chr14_+_64680854 1.207 ENST00000458046.2
SYNE2
spectrin repeat containing, nuclear envelope 2
chr18_+_13611763 1.206 ENST00000585931.1
LDLRAD4
low density lipoprotein receptor class A domain containing 4
chr11_+_1889880 1.194 ENST00000405957.2
LSP1
lymphocyte-specific protein 1
chrX_-_102319092 1.192 ENST00000372728.3
BEX1
brain expressed, X-linked 1
chr4_+_128554081 1.181 ENST00000335251.6
ENST00000296461.5
INTU

inturned planar cell polarity protein

chr1_+_160709055 1.180 ENST00000368043.3
ENST00000368042.3
ENST00000458602.2
ENST00000458104.2
SLAMF7



SLAM family member 7



chr11_+_7534999 1.178 ENST00000528947.1
ENST00000299492.4
PPFIBP2

PTPRF interacting protein, binding protein 2 (liprin beta 2)

chr1_+_160709029 1.170 ENST00000444090.2
ENST00000441662.2
SLAMF7

SLAM family member 7

chr19_+_41882598 1.167 ENST00000447302.2
ENST00000544232.1
ENST00000542945.1
ENST00000540732.1
TMEM91


CTC-435M10.3
transmembrane protein 91


2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial; Uncharacterized protein
chr2_+_143886877 1.167 ENST00000295095.6
ARHGAP15
Rho GTPase activating protein 15
chr11_+_121322832 1.166 ENST00000260197.7
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr3_+_98250743 1.162 ENST00000284311.3
GPR15
G protein-coupled receptor 15
chrX_-_40036520 1.156 ENST00000406200.2
ENST00000378455.4
ENST00000342274.4
BCOR


BCL6 corepressor


chr5_-_111091948 1.154 ENST00000447165.2
NREP
neuronal regeneration related protein
chr17_+_72462766 1.141 ENST00000392625.3
ENST00000361933.3
ENST00000310828.5
CD300A


CD300a molecule


chr16_+_57392684 1.134 ENST00000219235.4
CCL22
chemokine (C-C motif) ligand 22
chr1_+_32930647 1.134 ENST00000609129.1
ZBTB8B
zinc finger and BTB domain containing 8B
chr2_-_64881018 1.124 ENST00000313349.3
SERTAD2
SERTA domain containing 2
chr14_-_90085458 1.124 ENST00000345097.4
ENST00000555855.1
ENST00000555353.1
FOXN3


forkhead box N3


chr6_+_167704838 1.111 ENST00000366829.2
UNC93A
unc-93 homolog A (C. elegans)
chr14_+_100531615 1.109 ENST00000392920.3
EVL
Enah/Vasp-like
chr17_-_64216748 1.108 ENST00000585162.1
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr15_+_58724184 1.087 ENST00000433326.2
LIPC
lipase, hepatic
chr1_-_9129598 1.080 ENST00000535586.1
SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr1_-_207095324 1.075 ENST00000530505.1
ENST00000367091.3
ENST00000442471.2
FAIM3


Fas apoptotic inhibitory molecule 3


chr2_-_89442621 1.072 ENST00000492167.1
IGKV3-20
immunoglobulin kappa variable 3-20
chr16_-_28608424 1.067 ENST00000335715.4
SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr1_-_168513229 1.065 ENST00000367819.2
XCL2
chemokine (C motif) ligand 2
chr22_+_44464923 1.060 ENST00000404989.1
PARVB
parvin, beta
chr17_-_56494908 1.051 ENST00000577716.1
RNF43
ring finger protein 43
chr6_+_292051 1.046 ENST00000344450.5
DUSP22
dual specificity phosphatase 22
chr17_-_7018128 1.045 ENST00000380952.2
ENST00000254850.7
ASGR2

asialoglycoprotein receptor 2

chr6_+_13272904 1.044 ENST00000379335.3
ENST00000379329.1
PHACTR1

phosphatase and actin regulator 1

chr14_+_75988768 1.034 ENST00000286639.6
BATF
basic leucine zipper transcription factor, ATF-like
chr17_-_56494882 1.032 ENST00000584437.1
RNF43
ring finger protein 43
chr12_+_7055767 1.025 ENST00000447931.2
PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr5_-_42811986 1.023 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
SEPP1


selenoprotein P, plasma, 1


chr20_-_62199427 1.021 ENST00000427522.2
HELZ2
helicase with zinc finger 2, transcriptional coactivator
chr14_-_94854926 1.019 ENST00000402629.1
ENST00000556091.1
ENST00000554720.1
SERPINA1


serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1


chr15_-_20193370 1.014 ENST00000558565.2
IGHV3OR15-7
immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr1_+_17866290 1.006 ENST00000361221.3
ENST00000452522.1
ENST00000434513.1
ARHGEF10L


Rho guanine nucleotide exchange factor (GEF) 10-like


chr5_+_156696362 0.998 ENST00000377576.3
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr2_-_175462456 0.995 ENST00000409891.1
ENST00000410117.1
WIPF1

WAS/WASL interacting protein family, member 1

chr17_+_25958174 0.990 ENST00000313648.6
ENST00000577392.1
ENST00000584661.1
ENST00000413914.2
LGALS9



lectin, galactoside-binding, soluble, 9



chr13_+_113622810 0.988 ENST00000397030.1
MCF2L
MCF.2 cell line derived transforming sequence-like
chr15_+_75080883 0.984 ENST00000567571.1
CSK
c-src tyrosine kinase
chr1_-_159046617 0.984 ENST00000368130.4
AIM2
absent in melanoma 2
chr5_-_42812143 0.980 ENST00000514985.1
SEPP1
selenoprotein P, plasma, 1
chrX_+_115567767 0.972 ENST00000371900.4
SLC6A14
solute carrier family 6 (amino acid transporter), member 14
chr19_+_36203830 0.971 ENST00000262630.3
ZBTB32
zinc finger and BTB domain containing 32
chr15_+_41057818 0.971 ENST00000558467.1
GCHFR
GTP cyclohydrolase I feedback regulator
chr17_-_56494713 0.969 ENST00000407977.2
RNF43
ring finger protein 43
chr19_-_10445399 0.968 ENST00000592945.1
ICAM3
intercellular adhesion molecule 3
chr7_+_99971129 0.966 ENST00000394000.2
ENST00000350573.2
PILRA

paired immunoglobin-like type 2 receptor alpha

chr2_+_24714729 0.964 ENST00000406961.1
ENST00000405141.1
NCOA1

nuclear receptor coactivator 1

chr17_-_16875371 0.951 ENST00000437538.2
ENST00000583789.1
ENST00000261652.2
ENST00000579315.1
TNFRSF13B



tumor necrosis factor receptor superfamily, member 13B



chr11_-_117699413 0.947 ENST00000528014.1
FXYD2
FXYD domain containing ion transport regulator 2
chr19_-_51875894 0.942 ENST00000600427.1
ENST00000595217.1
ENST00000221978.5
NKG7


natural killer cell group 7 sequence


chr22_+_24823517 0.939 ENST00000496258.1
ENST00000337539.7
ADORA2A

adenosine A2a receptor

chr10_-_65028938 0.937 ENST00000402544.1
JMJD1C
jumonji domain containing 1C
chr7_-_100844193 0.935 ENST00000440203.2
ENST00000379423.3
ENST00000223114.4
MOGAT3


monoacylglycerol O-acyltransferase 3


chr7_-_29234802 0.934 ENST00000449801.1
ENST00000409850.1
CPVL

carboxypeptidase, vitellogenic-like

chr10_-_65028817 0.931 ENST00000542921.1
JMJD1C
jumonji domain containing 1C
chr2_-_175462934 0.929 ENST00000392546.2
ENST00000436221.1
WIPF1

WAS/WASL interacting protein family, member 1

chr9_+_117092149 0.928 ENST00000431067.2
ENST00000412657.1
ORM2

orosomucoid 2

chr2_+_11752379 0.928 ENST00000396123.1
GREB1
growth regulation by estrogen in breast cancer 1
chr6_+_107811162 0.927 ENST00000317357.5
SOBP
sine oculis binding protein homolog (Drosophila)
chr11_+_108093559 0.914 ENST00000278616.4
ATM
ataxia telangiectasia mutated
chr14_-_94789663 0.910 ENST00000557225.1
ENST00000341584.3
SERPINA6

serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6

chr20_+_61448376 0.909 ENST00000343916.3
COL9A3
collagen, type IX, alpha 3
chr1_+_158801095 0.900 ENST00000368141.4
MNDA
myeloid cell nuclear differentiation antigen
chr3_+_42947600 0.897 ENST00000328199.6
ENST00000541208.1
ZNF662

zinc finger protein 662

chr22_+_21133469 0.896 ENST00000406799.1
SERPIND1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr16_-_28621353 0.894 ENST00000567512.1
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr14_-_106994333 0.893 ENST00000390624.2
IGHV3-48
immunoglobulin heavy variable 3-48
chr6_+_31916733 0.891 ENST00000483004.1
CFB
complement factor B
chr1_-_9129895 0.890 ENST00000473209.1
SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr12_+_81471816 0.887 ENST00000261206.3
ACSS3
acyl-CoA synthetase short-chain family member 3
chr5_-_108745689 0.886 ENST00000361189.2
PJA2
praja ring finger 2, E3 ubiquitin protein ligase
chr3_-_98241760 0.884 ENST00000507874.1
ENST00000502299.1
ENST00000508659.1
ENST00000510545.1
ENST00000511667.1
ENST00000394185.2
ENST00000394181.2
ENST00000508902.1
ENST00000341181.6
ENST00000437922.1
ENST00000394180.2
CLDND1










claudin domain containing 1










chr14_-_106330458 0.884 ENST00000461719.1
IGHJ4
immunoglobulin heavy joining 4
chr1_+_32716840 0.875 ENST00000336890.5
LCK
lymphocyte-specific protein tyrosine kinase
chr12_-_719573 0.861 ENST00000397265.3
NINJ2
ninjurin 2
chr3_-_187454281 0.861 ENST00000232014.4
BCL6
B-cell CLL/lymphoma 6
chr7_+_102715315 0.861 ENST00000428183.2
ENST00000323716.3
ENST00000441711.2
ENST00000454559.1
ENST00000425331.1
ENST00000541300.1
ARMC10





armadillo repeat containing 10





chr15_-_37393406 0.858 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
MEIS2


Meis homeobox 2


chr12_-_110434096 0.853 ENST00000320063.9
ENST00000457474.2
ENST00000547815.1
ENST00000361006.5
GIT2



G protein-coupled receptor kinase interacting ArfGAP 2



chr17_-_26903900 0.853 ENST00000395319.3
ENST00000581807.1
ENST00000584086.1
ENST00000395321.2
ALDOC



aldolase C, fructose-bisphosphate



chr12_+_71833550 0.852 ENST00000266674.5
LGR5
leucine-rich repeat containing G protein-coupled receptor 5

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.0 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
1.3 5.0 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
1.2 3.5 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.7 2.2 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.7 2.1 GO:0001845 phagolysosome assembly(GO:0001845) phagosome maturation(GO:0090382)
0.6 1.9 GO:1903961 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) positive regulation of anion transmembrane transport(GO:1903961)
0.6 1.9 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.6 2.5 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.6 1.8 GO:0070340 detection of bacterial lipoprotein(GO:0042494) detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.6 4.0 GO:0015755 fructose transport(GO:0015755)
0.6 2.3 GO:0001969 activation of membrane attack complex(GO:0001905) regulation of activation of membrane attack complex(GO:0001969) positive regulation of activation of membrane attack complex(GO:0001970) positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.5 5.5 GO:0015074 DNA integration(GO:0015074)
0.5 0.5 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.5 2.0 GO:0033622 integrin activation(GO:0033622) regulation of integrin activation(GO:0033623) positive regulation of integrin activation(GO:0033625)
0.5 1.4 GO:0001907 cytolysis by symbiont of host cells(GO:0001897) killing by symbiont of host cells(GO:0001907) hemolysis by symbiont of host erythrocytes(GO:0019836) disruption by symbiont of host cell(GO:0044004) hemolysis in other organism(GO:0044179) positive regulation of circadian sleep/wake cycle, non-REM sleep(GO:0046010) cytolysis in other organism(GO:0051715) cytolysis in other organism involved in symbiotic interaction(GO:0051801) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.5 2.3 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.4 4.9 GO:0042832 defense response to protozoan(GO:0042832)
0.4 1.6 GO:0002313 mature B cell differentiation involved in immune response(GO:0002313)
0.4 1.2 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.4 0.8 GO:0070672 response to interleukin-15(GO:0070672)
0.4 1.4 GO:0006768 biotin metabolic process(GO:0006768)
0.3 0.7 GO:0002268 follicular dendritic cell activation(GO:0002266) follicular dendritic cell differentiation(GO:0002268)
0.3 1.4 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.3 1.7 GO:0050857 positive regulation of antigen receptor-mediated signaling pathway(GO:0050857) positive regulation of T cell receptor signaling pathway(GO:0050862)
0.3 1.3 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.3 1.0 GO:0043095 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.3 0.9 GO:0048143 obsolete induction of apoptosis in response to chemical stimulus(GO:0031558) astrocyte activation(GO:0048143)
0.3 3.4 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.3 7.6 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.3 0.3 GO:0071361 cellular response to ethanol(GO:0071361)
0.3 0.6 GO:0001562 response to protozoan(GO:0001562)
0.3 4.8 GO:0032814 regulation of natural killer cell activation(GO:0032814)
0.3 2.7 GO:0050884 neuromuscular process controlling posture(GO:0050884)
0.3 4.6 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.3 1.6 GO:0070168 negative regulation of bone mineralization(GO:0030502) negative regulation of biomineral tissue development(GO:0070168)
0.3 4.7 GO:0006906 vesicle fusion(GO:0006906)
0.3 0.8 GO:0046210 nitric oxide catabolic process(GO:0046210)
0.3 1.0 GO:0033986 response to methanol(GO:0033986) response to chromate(GO:0046687)
0.2 0.2 GO:0010044 response to aluminum ion(GO:0010044)
0.2 1.7 GO:0002634 regulation of germinal center formation(GO:0002634)
0.2 0.9 GO:0002682 regulation of immune system process(GO:0002682)
0.2 0.6 GO:0003289 septum primum development(GO:0003284) atrial septum primum morphogenesis(GO:0003289)
0.2 0.8 GO:0050653 UDP-N-acetylgalactosamine metabolic process(GO:0019276) chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.2 1.2 GO:0099515 nuclear migration along microfilament(GO:0031022) actin filament-based transport(GO:0099515)
0.2 0.8 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.2 0.6 GO:0010430 ethanol catabolic process(GO:0006068) fatty acid omega-oxidation(GO:0010430)
0.2 0.6 GO:0061298 retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.2 1.5 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.2 0.2 GO:0006828 manganese ion transport(GO:0006828)
0.2 0.9 GO:0042159 lipoprotein catabolic process(GO:0042159)
0.2 1.4 GO:0046628 positive regulation of insulin receptor signaling pathway(GO:0046628) positive regulation of cellular response to insulin stimulus(GO:1900078)
0.2 0.2 GO:0042036 negative regulation of cytokine biosynthetic process(GO:0042036)
0.2 8.9 GO:0006958 complement activation, classical pathway(GO:0006958)
0.2 2.3 GO:0046697 decidualization(GO:0046697)
0.2 3.9 GO:0051923 sulfation(GO:0051923)
0.2 3.5 GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732)
0.1 0.4 GO:1990170 detoxification of cadmium ion(GO:0071585) stress response to cadmium ion(GO:1990170)
0.1 0.4 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.1 4.1 GO:0045069 regulation of viral genome replication(GO:0045069)
0.1 0.6 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1 1.1 GO:0046831 regulation of RNA export from nucleus(GO:0046831)
0.1 0.6 GO:0008298 intracellular mRNA localization(GO:0008298)
0.1 1.9 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.1 0.5 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.1 1.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 0.3 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.1 0.3 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.1 0.5 GO:0030202 heparin metabolic process(GO:0030202)
0.1 1.0 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.1 0.6 GO:0010957 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.1 1.9 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.1 0.4 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.1 0.4 GO:0034625 fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 1.8 GO:0006979 response to oxidative stress(GO:0006979)
0.1 1.1 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 0.7 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.1 3.4 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.1 0.4 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.1 0.3 GO:0032025 response to cobalt ion(GO:0032025)
0.1 0.3 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.1 1.8 GO:0006071 glycerol metabolic process(GO:0006071)
0.1 0.4 GO:0003057 regulation of the force of heart contraction by chemical signal(GO:0003057)
0.1 0.3 GO:0046520 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520)
0.1 0.2 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1 0.2 GO:0019530 taurine metabolic process(GO:0019530)
0.1 1.9 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.1 0.4 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 1.4 GO:0006787 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.1 0.6 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.1 0.3 GO:2000858 renin-angiotensin regulation of aldosterone production(GO:0002018) regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072) positive regulation of NAD(P)H oxidase activity(GO:0033864) mineralocorticoid secretion(GO:0035931) aldosterone secretion(GO:0035932) regulation of mineralocorticoid secretion(GO:2000855) regulation of aldosterone secretion(GO:2000858)
0.1 0.5 GO:0018101 protein citrullination(GO:0018101)
0.1 0.4 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.1 0.3 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079) chromosome movement towards spindle pole(GO:0051305)
0.1 0.7 GO:0046618 drug export(GO:0046618)
0.1 0.7 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.1 0.4 GO:0001941 postsynaptic membrane organization(GO:0001941)
0.1 0.6 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272) embryonic skeletal joint development(GO:0072498)
0.1 0.3 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
0.1 0.6 GO:0010459 negative regulation of heart rate(GO:0010459)
0.1 1.5 GO:0006000 fructose metabolic process(GO:0006000)
0.1 0.4 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.1 0.7 GO:0060323 head morphogenesis(GO:0060323)
0.1 0.5 GO:0006772 thiamine metabolic process(GO:0006772)
0.1 0.4 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.1 0.6 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 0.6 GO:0045007 depurination(GO:0045007)
0.1 0.2 GO:0032119 sequestering of zinc ion(GO:0032119) antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) regulation of sequestering of zinc ion(GO:0061088)
0.1 0.2 GO:0006382 adenosine to inosine editing(GO:0006382)
0.1 1.6 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.1 0.5 GO:0032494 response to peptidoglycan(GO:0032494)
0.1 1.4 GO:0045730 respiratory burst(GO:0045730)
0.1 1.9 GO:0002286 T cell activation involved in immune response(GO:0002286)
0.1 0.5 GO:0032495 response to muramyl dipeptide(GO:0032495)
0.1 3.3 GO:0046324 regulation of glucose import(GO:0046324)
0.1 0.3 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 1.1 GO:0051319 mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.1 0.5 GO:0061756 leukocyte tethering or rolling(GO:0050901) leukocyte adhesion to vascular endothelial cell(GO:0061756)
0.1 0.3 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.1 0.5 GO:0042693 muscle cell fate commitment(GO:0042693)
0.1 1.7 GO:0045806 negative regulation of endocytosis(GO:0045806)
0.1 1.2 GO:0030101 natural killer cell activation(GO:0030101)
0.1 0.3 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1 1.4 GO:0090630 activation of GTPase activity(GO:0090630)
0.1 1.3 GO:0001578 microtubule bundle formation(GO:0001578)
0.1 5.6 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.1 0.2 GO:0042118 endothelial cell activation(GO:0042118)
0.1 0.5 GO:0060042 retina morphogenesis in camera-type eye(GO:0060042)
0.1 0.2 GO:0007285 primary spermatocyte growth(GO:0007285)
0.1 0.2 GO:0045667 regulation of osteoblast differentiation(GO:0045667) positive regulation of ossification(GO:0045778)
0.1 0.1 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.1 0.6 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.1 0.5 GO:0006983 ER overload response(GO:0006983)
0.1 0.2 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.1 0.5 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 0.3 GO:0055009 atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
0.1 0.3 GO:0032148 activation of protein kinase B activity(GO:0032148)
0.1 1.7 GO:0051925 obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.1 0.1 GO:0070849 response to epidermal growth factor(GO:0070849)
0.1 0.6 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.1 0.2 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 0.2 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.1 0.2 GO:0010508 positive regulation of autophagy(GO:0010508)
0.1 0.1 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.1 0.2 GO:0040016 embryonic cleavage(GO:0040016)
0.1 1.8 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 0.4 GO:0051571 positive regulation of histone H3-K4 methylation(GO:0051571)
0.1 0.1 GO:0007538 primary sex determination(GO:0007538)
0.1 0.4 GO:0043954 cell junction maintenance(GO:0034331) cellular component maintenance(GO:0043954) cell-cell junction maintenance(GO:0045217)
0.1 0.2 GO:0019240 citrulline biosynthetic process(GO:0019240)
0.1 0.8 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1 0.6 GO:0006379 mRNA cleavage(GO:0006379)
0.1 0.2 GO:0006922 obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.1 3.4 GO:0006968 cellular defense response(GO:0006968)
0.1 0.2 GO:0051451 myoblast migration(GO:0051451)
0.1 0.9 GO:0030155 regulation of cell adhesion(GO:0030155)
0.0 0.4 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.1 GO:0060080 inhibitory postsynaptic potential(GO:0060080)
0.0 0.1 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.0 0.4 GO:0006984 ER-nucleus signaling pathway(GO:0006984)
0.0 0.3 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.7 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.6 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.4 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.6 GO:0031000 response to caffeine(GO:0031000)
0.0 0.3 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.6 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 2.2 GO:0055088 lipid homeostasis(GO:0055088)
0.0 0.1 GO:0014831 intestine smooth muscle contraction(GO:0014827) gastro-intestinal system smooth muscle contraction(GO:0014831)
0.0 0.5 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.0 GO:0030432 peristalsis(GO:0030432)
0.0 0.1 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 3.7 GO:0008203 cholesterol metabolic process(GO:0008203)
0.0 3.7 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.8 GO:0032011 ARF protein signal transduction(GO:0032011)
0.0 0.8 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.0 0.1 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.5 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.2 GO:0015705 iodide transport(GO:0015705)
0.0 2.7 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 0.1 GO:0071635 negative regulation of transforming growth factor beta production(GO:0071635)
0.0 0.2 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.2 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.7 GO:0008211 glucocorticoid metabolic process(GO:0008211)
0.0 0.1 GO:0016071 mRNA metabolic process(GO:0016071)
0.0 0.2 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.7 GO:0060334 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.1 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.0 2.2 GO:0050680 negative regulation of epithelial cell proliferation(GO:0050680)
0.0 0.2 GO:0071305 cellular response to vitamin D(GO:0071305)
0.0 0.1 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.4 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.4 GO:0006378 mRNA polyadenylation(GO:0006378)
0.0 0.1 GO:0010447 response to acidic pH(GO:0010447)
0.0 2.9 GO:0007204 positive regulation of cytosolic calcium ion concentration(GO:0007204)
0.0 3.9 GO:0043087 regulation of GTPase activity(GO:0043087)
0.0 0.3 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.8 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.5 GO:0000045 autophagosome assembly(GO:0000045) autophagosome organization(GO:1905037)
0.0 2.1 GO:0006986 response to unfolded protein(GO:0006986)
0.0 4.9 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.0 0.2 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.1 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.0 0.3 GO:0006734 NADH metabolic process(GO:0006734)
0.0 1.9 GO:0071357 response to type I interferon(GO:0034340) type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 0.1 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.6 GO:0071593 T cell activation(GO:0042110) leukocyte aggregation(GO:0070486) T cell aggregation(GO:0070489) lymphocyte aggregation(GO:0071593)
0.0 0.1 GO:0045953 negative regulation of natural killer cell mediated immunity(GO:0002716) negative regulation of natural killer cell mediated cytotoxicity(GO:0045953)
0.0 0.1 GO:0015871 choline transport(GO:0015871)
0.0 0.1 GO:0001692 histamine metabolic process(GO:0001692)
0.0 0.0 GO:0009146 purine nucleoside triphosphate catabolic process(GO:0009146) purine deoxyribonucleotide catabolic process(GO:0009155) deoxyribonucleoside triphosphate catabolic process(GO:0009204) purine deoxyribonucleoside triphosphate catabolic process(GO:0009217)
0.0 0.1 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.2 GO:0015695 organic cation transport(GO:0015695)
0.0 0.2 GO:0016180 snRNA processing(GO:0016180)
0.0 0.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.1 GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.0 0.5 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 0.1 GO:0030578 nuclear body organization(GO:0030575) PML body organization(GO:0030578)
0.0 0.0 GO:0070474 uterine smooth muscle contraction(GO:0070471) regulation of uterine smooth muscle contraction(GO:0070472) positive regulation of uterine smooth muscle contraction(GO:0070474)
0.0 0.1 GO:0051930 regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931)
0.0 0.3 GO:0001702 gastrulation with mouth forming second(GO:0001702)
0.0 0.1 GO:0032414 positive regulation of ion transmembrane transporter activity(GO:0032414)
0.0 0.1 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.1 GO:0007207 phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0 0.1 GO:0018106 peptidyl-histidine phosphorylation(GO:0018106)
0.0 0.8 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.5 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.9 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.2 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) positive regulation of ERBB signaling pathway(GO:1901186)
0.0 0.2 GO:0032876 regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0 0.1 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.1 GO:0006305 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0 0.1 GO:0006051 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.0 0.1 GO:0016246 RNA interference(GO:0016246)
0.0 0.1 GO:0071294 cellular response to zinc ion(GO:0071294)
0.0 0.5 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 0.7 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.2 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.2 GO:0019883 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.1 GO:0003279 cardiac septum development(GO:0003279)
0.0 0.1 GO:0007270 neuron-neuron synaptic transmission(GO:0007270)
0.0 0.2 GO:0006260 DNA replication(GO:0006260)
0.0 0.0 GO:0002252 immune effector process(GO:0002252)
0.0 0.8 GO:0042472 inner ear morphogenesis(GO:0042472)
0.0 0.1 GO:0006111 regulation of gluconeogenesis(GO:0006111)
0.0 0.1 GO:0032496 response to lipopolysaccharide(GO:0032496)
0.0 0.1 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194) negative regulation of cAMP metabolic process(GO:0030815) negative regulation of cAMP biosynthetic process(GO:0030818) negative regulation of cyclase activity(GO:0031280) negative regulation of lyase activity(GO:0051350)
0.0 0.1 GO:0009214 cyclic nucleotide catabolic process(GO:0009214)
0.0 0.3 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.1 GO:0007549 dosage compensation(GO:0007549)
0.0 0.1 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.0 0.1 GO:0046718 entry into host cell(GO:0030260) entry into host(GO:0044409) viral entry into host cell(GO:0046718) entry into cell of other organism involved in symbiotic interaction(GO:0051806) entry into other organism involved in symbiotic interaction(GO:0051828)
0.0 0.0 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.0 GO:0042391 regulation of membrane potential(GO:0042391)
0.0 0.2 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 0.1 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.1 GO:0002051 osteoblast fate commitment(GO:0002051) chondrocyte development(GO:0002063)
0.0 0.7 GO:0006694 steroid biosynthetic process(GO:0006694)
0.0 0.1 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 0.4 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.2 GO:0006386 transcription elongation from RNA polymerase III promoter(GO:0006385) termination of RNA polymerase III transcription(GO:0006386)
0.0 0.0 GO:0002124 aggressive behavior(GO:0002118) territorial aggressive behavior(GO:0002124) brainstem development(GO:0003360) vocalization behavior(GO:0071625)
0.0 0.1 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.2 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.2 GO:0042168 heme metabolic process(GO:0042168)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 6.7 GO:0001891 phagocytic cup(GO:0001891)
0.6 1.8 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.5 1.6 GO:0031904 endosome lumen(GO:0031904)
0.5 2.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.5 3.3 GO:0000300 obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.4 7.5 GO:0042613 MHC class II protein complex(GO:0042613)
0.3 1.3 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.3 1.0 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.3 4.1 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.2 2.0 GO:0000242 pericentriolar material(GO:0000242)
0.2 0.9 GO:0005594 collagen type IX trimer(GO:0005594)
0.2 1.9 GO:0043020 NADPH oxidase complex(GO:0043020)
0.2 0.7 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.2 0.7 GO:0097651 phosphatidylinositol 3-kinase complex, class IA(GO:0005943) phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.2 0.5 GO:0042629 mast cell granule(GO:0042629)
0.2 3.8 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.2 0.9 GO:0098984 asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.2 2.3 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.1 1.9 GO:0034451 centriolar satellite(GO:0034451)
0.1 1.8 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 0.5 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 5.3 GO:0098636 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.1 0.6 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.9 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 1.3 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.6 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 1.1 GO:0042627 chylomicron(GO:0042627)
0.1 0.7 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.1 0.7 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 2.9 GO:0005624 obsolete membrane fraction(GO:0005624)
0.1 0.7 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 0.6 GO:0000796 condensin complex(GO:0000796)
0.1 0.3 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 0.4 GO:0070552 BRISC complex(GO:0070552)
0.1 1.0 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 3.2 GO:0005884 actin filament(GO:0005884)
0.1 0.2 GO:0016939 kinesin II complex(GO:0016939)
0.1 0.7 GO:1903561 extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.1 3.0 GO:0030863 cortical cytoskeleton(GO:0030863)
0.1 1.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 0.6 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.5 GO:0030673 axolemma(GO:0030673)
0.0 1.3 GO:0005859 muscle myosin complex(GO:0005859)
0.0 1.0 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.3 GO:0031512 motile primary cilium(GO:0031512)
0.0 0.2 GO:0070288 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.0 1.1 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.4 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.6 GO:0030530 obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0 0.4 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.1 GO:0042599 lamellar body(GO:0042599)
0.0 0.1 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.4 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.9 GO:0000299 obsolete integral to membrane of membrane fraction(GO:0000299)
0.0 1.1 GO:0031526 brush border membrane(GO:0031526)
0.0 1.0 GO:0005844 polysome(GO:0005844)
0.0 5.3 GO:0005925 focal adhesion(GO:0005925)
0.0 0.4 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.7 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.3 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.3 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.0 1.1 GO:0030532 small nuclear ribonucleoprotein complex(GO:0030532)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 0.6 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.8 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.1 GO:0031264 death-inducing signaling complex(GO:0031264)
0.0 0.2 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 2.0 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.7 GO:0031201 SNARE complex(GO:0031201)
0.0 0.1 GO:0033269 internode region of axon(GO:0033269)
0.0 0.6 GO:0043235 receptor complex(GO:0043235)
0.0 0.3 GO:0030027 lamellipodium(GO:0030027)
0.0 1.9 GO:0005911 cell-cell junction(GO:0005911)
0.0 0.1 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 2.3 GO:0005792 obsolete microsome(GO:0005792)
0.0 0.5 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 0.0 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.5 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.3 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.3 GO:0016235 aggresome(GO:0016235)
0.0 0.9 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 0.6 GO:0045095 keratin filament(GO:0045095)
0.0 0.3 GO:0030175 filopodium(GO:0030175)
0.0 0.8 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.2 GO:0010008 endosome membrane(GO:0010008) endosomal part(GO:0044440)
0.0 12.1 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.1 GO:0032982 myosin filament(GO:0032982)
0.0 1.2 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.5 GO:0005657 replication fork(GO:0005657)
0.0 0.2 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.2 GO:0030914 STAGA complex(GO:0030914)
0.0 0.2 GO:0070688 MLL5-L complex(GO:0070688)
0.0 2.1 GO:0005769 early endosome(GO:0005769)
0.0 0.1 GO:0005883 neurofilament(GO:0005883)
0.0 2.5 GO:0000228 nuclear chromosome(GO:0000228)
0.0 0.6 GO:0042645 mitochondrial nucleoid(GO:0042645)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.5 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.3 GO:0005871 kinesin complex(GO:0005871)
0.0 0.1 GO:0090568 NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)
0.0 0.2 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.2 GO:0005811 lipid particle(GO:0005811)
0.0 0.2 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.2 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.1 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 0.3 GO:0016592 mediator complex(GO:0016592)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.0 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
1.4 5.5 GO:0008907 integrase activity(GO:0008907)
0.6 2.5 GO:0019862 IgA binding(GO:0019862)
0.6 4.0 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.6 1.7 GO:0042610 CD8 receptor binding(GO:0042610)
0.5 1.5 GO:0004913 interleukin-4 receptor activity(GO:0004913) interleukin-2 binding(GO:0019976)
0.5 3.3 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.4 6.0 GO:0003840 gamma-glutamyltransferase activity(GO:0003840)
0.4 5.8 GO:0032395 MHC class II receptor activity(GO:0032395)
0.4 1.6 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.3 1.0 GO:0043515 kinetochore binding(GO:0043515)
0.3 1.7 GO:0004803 transposase activity(GO:0004803)
0.3 1.0 GO:0044549 GTP cyclohydrolase binding(GO:0044549)
0.3 1.6 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.3 3.4 GO:0004568 chitinase activity(GO:0004568)
0.3 0.9 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.3 1.2 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.3 2.1 GO:0030492 hemoglobin binding(GO:0030492)
0.3 0.9 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.3 0.8 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.3 2.5 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.3 2.2 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.3 0.8 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.3 2.3 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.2 0.7 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.2 3.7 GO:0030276 clathrin binding(GO:0030276)
0.2 1.6 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.2 1.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.2 1.5 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.2 1.9 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.2 4.9 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.2 0.8 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.2 0.6 GO:0035276 ethanol binding(GO:0035276)
0.2 1.0 GO:0005534 galactose binding(GO:0005534)
0.2 0.6 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.2 0.8 GO:0015232 heme transporter activity(GO:0015232)
0.2 5.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.2 2.3 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.2 2.8 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.2 0.7 GO:0017040 ceramidase activity(GO:0017040)
0.2 0.5 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.2 3.0 GO:0005522 profilin binding(GO:0005522)
0.2 0.9 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.2 0.5 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.2 1.6 GO:0001848 complement binding(GO:0001848)
0.2 0.9 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.2 1.4 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.2 1.2 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.2 1.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 3.9 GO:0042056 chemoattractant activity(GO:0042056)
0.1 0.4 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.1 0.4 GO:0031997 N-terminal myristoylation domain binding(GO:0031997)
0.1 0.4 GO:0031755 endothelial differentiation G-protein coupled receptor binding(GO:0031753) Edg-2 lysophosphatidic acid receptor binding(GO:0031755)
0.1 1.5 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 3.0 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 0.7 GO:0034711 inhibin binding(GO:0034711)
0.1 0.8 GO:0004904 interferon receptor activity(GO:0004904)
0.1 0.7 GO:0043559 insulin binding(GO:0043559)
0.1 0.5 GO:0042910 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.1 0.3 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polynucleotide 5'-hydroxyl-kinase activity(GO:0051731) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.1 0.3 GO:0035184 histone threonine kinase activity(GO:0035184)
0.1 0.6 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 0.4 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.1 2.7 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.1 1.8 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 0.7 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.1 0.5 GO:0032408 MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
0.1 1.8 GO:0017127 cholesterol transporter activity(GO:0017127)
0.1 0.9 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.4 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.1 1.4 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.1 1.3 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 1.1 GO:0015643 toxic substance binding(GO:0015643)
0.1 0.3 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.1 0.6 GO:0019863 IgE binding(GO:0019863)
0.1 0.4 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.1 0.5 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.1 0.4 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 0.5 GO:0015520 tetracycline:proton antiporter activity(GO:0015520)
0.1 0.3 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 0.3 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.1 0.3 GO:0042808 obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.1 0.6 GO:0004339 glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.1 0.7 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 0.4 GO:0070363 mitochondrial light strand promoter sense binding(GO:0070363)
0.1 0.2 GO:0071723 lipopeptide binding(GO:0071723)
0.1 0.5 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 1.1 GO:0008199 ferric iron binding(GO:0008199)
0.1 1.7 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.6 GO:0001968 fibronectin binding(GO:0001968)
0.1 0.9 GO:0016405 CoA-ligase activity(GO:0016405)
0.1 0.6 GO:0004522 ribonuclease A activity(GO:0004522)
0.1 0.4 GO:0009922 fatty acid elongase activity(GO:0009922)
0.1 0.3 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 1.7 GO:0008430 selenium binding(GO:0008430)
0.1 0.3 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.1 0.3 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.1 0.3 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.1 0.6 GO:0019534 toxin transporter activity(GO:0019534)
0.1 0.5 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.1 3.1 GO:0005158 insulin receptor binding(GO:0005158)
0.1 6.3 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.1 0.5 GO:0016778 diphosphotransferase activity(GO:0016778)
0.1 3.2 GO:0003823 antigen binding(GO:0003823)
0.1 0.2 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 0.2 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.1 0.2 GO:0046848 hydroxyapatite binding(GO:0046848)
0.1 0.1 GO:0047042 androsterone dehydrogenase (B-specific) activity(GO:0047042)
0.1 0.2 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 0.4 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1 0.4 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.3 GO:0015057 thrombin receptor activity(GO:0015057)
0.1 0.4 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 0.2 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.1 3.2 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 0.3 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.4 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.2 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 1.9 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.4 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.5 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.2 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 6.5 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.4 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.2 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.0 0.8 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.3 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.0 0.6 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.0 0.6 GO:0042166 acetylcholine binding(GO:0042166)
0.0 0.3 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.3 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.7 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.2 GO:0035326 enhancer binding(GO:0035326)
0.0 0.4 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 4.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.2 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 0.2 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.0 1.1 GO:0005254 chloride channel activity(GO:0005254)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.1 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 2.0 GO:0003704 obsolete specific RNA polymerase II transcription factor activity(GO:0003704)
0.0 0.8 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.7 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.4 GO:0051635 obsolete bacterial cell surface binding(GO:0051635)
0.0 0.4 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.0 0.4 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.9 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.3 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.1 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.0 0.4 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.5 GO:0051117 ATPase binding(GO:0051117)
0.0 0.3 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.2 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0004607 phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.0 0.4 GO:0090079 translation regulator activity, nucleic acid binding(GO:0090079)
0.0 0.3 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 2.3 GO:0001071 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 0.1 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.0 0.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.4 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.4 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.1 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.0 0.2 GO:0008159 obsolete positive transcription elongation factor activity(GO:0008159)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.2 GO:0004457 lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
0.0 2.0 GO:0051015 actin filament binding(GO:0051015)
0.0 0.2 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 9.5 GO:0030695 GTPase regulator activity(GO:0030695)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.4 GO:0051787 misfolded protein binding(GO:0051787)
0.0 4.7 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.0 0.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.0 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.2 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.0 0.5 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.1 GO:0016972 thiol oxidase activity(GO:0016972)
0.0 0.1 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.0 0.2 GO:0005497 androgen binding(GO:0005497)
0.0 0.3 GO:0030528 obsolete transcription regulator activity(GO:0030528)
0.0 0.1 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.2 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.0 3.6 GO:0003702 obsolete RNA polymerase II transcription factor activity(GO:0003702)
0.0 0.5 GO:0030552 cAMP binding(GO:0030552)
0.0 0.5 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.2 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.5 GO:0008483 transaminase activity(GO:0008483)
0.0 0.2 GO:0001614 purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502)
0.0 0.2 GO:0016595 glutamate binding(GO:0016595)
0.0 0.3 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.4 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.6 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.3 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.1 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
0.0 0.2 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.3 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.4 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.8 GO:0008009 chemokine activity(GO:0008009)
0.0 0.4 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.1 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.0 1.4 GO:0042393 histone binding(GO:0042393)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.7 GO:0001948 glycoprotein binding(GO:0001948)
0.0 0.1 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.2 GO:0005521 lamin binding(GO:0005521)
0.0 0.3 GO:0019213 deacetylase activity(GO:0019213)
0.0 0.1 GO:0051378 serotonin binding(GO:0051378)
0.0 0.3 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.0 GO:0004946 bombesin receptor activity(GO:0004946)
0.0 0.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.5 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 0.3 GO:0030332 cyclin binding(GO:0030332)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.0 0.6 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.1 GO:0050780 dopamine receptor binding(GO:0050780)
0.0 0.4 GO:0019843 rRNA binding(GO:0019843)
0.0 0.3 GO:0004386 helicase activity(GO:0004386)
0.0 0.0 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.1 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.4 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.0 GO:0004083 bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.0 0.0 GO:0047708 biotinidase activity(GO:0047708)
0.0 0.1 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.3 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.1 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.3 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)
0.0 0.5 GO:0016875 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.2 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 0.1 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 7.2 ST_TUMOR_NECROSIS_FACTOR_PATHWAY Tumor Necrosis Factor Pathway.
0.1 0.4 ST_PAC1_RECEPTOR_PATHWAY PAC1 Receptor Pathway
0.1 6.4 SIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.1 1.4 ST_GAQ_PATHWAY G alpha q Pathway
0.1 0.8 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 2.4 ST_B_CELL_ANTIGEN_RECEPTOR B Cell Antigen Receptor
0.1 1.5 ST_INTERLEUKIN_4_PATHWAY Interleukin 4 (IL-4) Pathway
0.1 0.6 ST_INTERFERON_GAMMA_PATHWAY Interferon gamma pathway.
0.1 3.1 ST_T_CELL_SIGNAL_TRANSDUCTION T Cell Signal Transduction
0.0 0.7 ST_GRANULE_CELL_SURVIVAL_PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.3 SIG_IL4RECEPTOR_IN_B_LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.1 ST_IL_13_PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.3 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.3 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.3 ST_GA12_PATHWAY G alpha 12 Pathway
0.0 1.2 ST_INTEGRIN_SIGNALING_PATHWAY Integrin Signaling Pathway
0.0 0.3 SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES Genes related to PIP3 signaling in cardiac myocytes