Motif ID: RUNX3_BCL11A
Z-value: 1.502
Transcription factors associated with RUNX3_BCL11A:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| BCL11A | ENSG00000119866.16 | BCL11A |
| RUNX3 | ENSG00000020633.14 | RUNX3 |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 2.5 | GO:0043316 | natural killer cell activation involved in immune response(GO:0002323) cytotoxic T cell degranulation(GO:0043316) natural killer cell degranulation(GO:0043320) |
| 0.3 | 1.0 | GO:0002677 | negative regulation of chronic inflammatory response(GO:0002677) |
| 0.3 | 2.1 | GO:0002051 | osteoblast fate commitment(GO:0002051) |
| 0.3 | 1.3 | GO:0071801 | podosome assembly(GO:0071800) regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803) |
| 0.3 | 0.8 | GO:0002378 | immunoglobulin biosynthetic process(GO:0002378) |
| 0.3 | 1.1 | GO:0070933 | histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933) |
| 0.2 | 1.1 | GO:0001302 | replicative cell aging(GO:0001302) female genitalia morphogenesis(GO:0048807) |
| 0.2 | 0.6 | GO:0030205 | dermatan sulfate metabolic process(GO:0030205) dermatan sulfate biosynthetic process(GO:0030208) |
| 0.1 | 0.7 | GO:0034204 | lipid translocation(GO:0034204) phospholipid translocation(GO:0045332) |
| 0.1 | 1.7 | GO:0032817 | regulation of natural killer cell proliferation(GO:0032817) |
| 0.1 | 0.9 | GO:0050857 | positive regulation of antigen receptor-mediated signaling pathway(GO:0050857) |
| 0.1 | 0.6 | GO:0045046 | protein import into peroxisome membrane(GO:0045046) |
| 0.1 | 0.4 | GO:0051547 | regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549) |
| 0.1 | 0.8 | GO:0046831 | regulation of RNA export from nucleus(GO:0046831) |
| 0.1 | 1.3 | GO:0031498 | nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986) |
| 0.1 | 0.4 | GO:0043490 | malate-aspartate shuttle(GO:0043490) |
| 0.1 | 1.3 | GO:1901797 | negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797) |
| 0.1 | 0.5 | GO:0030951 | establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) |
| 0.1 | 0.5 | GO:0099515 | nuclear migration along microfilament(GO:0031022) actin filament-based transport(GO:0099515) |
| 0.1 | 0.3 | GO:0097237 | response to cobalt ion(GO:0032025) cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237) |
| 0.1 | 0.2 | GO:0060557 | positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559) |
| 0.1 | 0.9 | GO:0006030 | chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032) |
| 0.1 | 0.7 | GO:0051552 | flavone metabolic process(GO:0051552) |
| 0.1 | 0.6 | GO:0071353 | cellular response to interleukin-4(GO:0071353) |
| 0.1 | 0.7 | GO:0071692 | sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116) |
| 0.1 | 0.4 | GO:0030578 | nuclear body organization(GO:0030575) PML body organization(GO:0030578) |
| 0.1 | 0.5 | GO:0048296 | isotype switching to IgA isotypes(GO:0048290) regulation of isotype switching to IgA isotypes(GO:0048296) positive regulation of isotype switching to IgA isotypes(GO:0048298) |
| 0.1 | 0.7 | GO:0001562 | response to protozoan(GO:0001562) |
| 0.1 | 1.5 | GO:0045730 | respiratory burst(GO:0045730) |
| 0.1 | 0.2 | GO:2000001 | regulation of DNA damage checkpoint(GO:2000001) |
| 0.1 | 1.8 | GO:0045069 | regulation of viral genome replication(GO:0045069) |
| 0.1 | 0.2 | GO:0006597 | spermine biosynthetic process(GO:0006597) |
| 0.1 | 0.2 | GO:0051823 | regulation of synapse structural plasticity(GO:0051823) |
| 0.1 | 1.0 | GO:0006906 | vesicle fusion(GO:0006906) |
| 0.1 | 1.5 | GO:0045103 | intermediate filament-based process(GO:0045103) |
| 0.1 | 0.6 | GO:0016180 | snRNA processing(GO:0016180) |
| 0.1 | 0.2 | GO:0045938 | regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) positive regulation of circadian sleep/wake cycle, sleep(GO:0045938) |
| 0.1 | 0.4 | GO:0060122 | auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088) inner ear receptor stereocilium organization(GO:0060122) |
| 0.0 | 1.4 | GO:0002286 | T cell activation involved in immune response(GO:0002286) |
| 0.0 | 0.6 | GO:0046827 | positive regulation of protein export from nucleus(GO:0046827) |
| 0.0 | 0.2 | GO:0048304 | positive regulation of isotype switching to IgG isotypes(GO:0048304) |
| 0.0 | 0.1 | GO:0000354 | cis assembly of pre-catalytic spliceosome(GO:0000354) |
| 0.0 | 0.1 | GO:0070171 | negative regulation of tooth mineralization(GO:0070171) |
| 0.0 | 0.7 | GO:0007020 | microtubule nucleation(GO:0007020) |
| 0.0 | 0.2 | GO:0060164 | regulation of timing of neuron differentiation(GO:0060164) |
| 0.0 | 0.3 | GO:0043415 | positive regulation of skeletal muscle tissue regeneration(GO:0043415) regulation of skeletal muscle tissue regeneration(GO:0043416) |
| 0.0 | 0.6 | GO:0042976 | activation of Janus kinase activity(GO:0042976) |
| 0.0 | 0.2 | GO:0035520 | monoubiquitinated protein deubiquitination(GO:0035520) |
| 0.0 | 0.1 | GO:0097300 | necroptotic process(GO:0070266) programmed necrotic cell death(GO:0097300) |
| 0.0 | 0.1 | GO:0009992 | cellular water homeostasis(GO:0009992) |
| 0.0 | 0.1 | GO:0050955 | thermoception(GO:0050955) |
| 0.0 | 0.4 | GO:0051085 | chaperone mediated protein folding requiring cofactor(GO:0051085) |
| 0.0 | 3.5 | GO:0031295 | lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295) |
| 0.0 | 0.2 | GO:0021516 | dorsal spinal cord development(GO:0021516) |
| 0.0 | 0.3 | GO:0043497 | regulation of protein heterodimerization activity(GO:0043497) |
| 0.0 | 0.2 | GO:0002024 | diet induced thermogenesis(GO:0002024) adaptive thermogenesis(GO:1990845) |
| 0.0 | 0.2 | GO:0071354 | cellular response to interleukin-6(GO:0071354) |
| 0.0 | 0.1 | GO:0015722 | canalicular bile acid transport(GO:0015722) pyrimidine nucleobase transport(GO:0015855) |
| 0.0 | 0.7 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
| 0.0 | 0.2 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway(GO:0048387) |
| 0.0 | 0.5 | GO:0043968 | histone H2A acetylation(GO:0043968) |
| 0.0 | 0.1 | GO:0018027 | peptidyl-lysine dimethylation(GO:0018027) |
| 0.0 | 0.2 | GO:0007141 | male meiosis I(GO:0007141) |
| 0.0 | 0.2 | GO:0048892 | sensory system development(GO:0048880) lateral line nerve development(GO:0048892) lateral line nerve glial cell differentiation(GO:0048895) lateral line system development(GO:0048925) lateral line nerve glial cell development(GO:0048937) iridophore differentiation(GO:0050935) |
| 0.0 | 0.0 | GO:0001973 | adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588) |
| 0.0 | 0.2 | GO:0030030 | cell projection organization(GO:0030030) |
| 0.0 | 0.2 | GO:0060042 | retina morphogenesis in camera-type eye(GO:0060042) |
| 0.0 | 0.4 | GO:0007340 | acrosome reaction(GO:0007340) |
| 0.0 | 0.1 | GO:0006384 | transcription initiation from RNA polymerase III promoter(GO:0006384) |
| 0.0 | 0.2 | GO:0006776 | vitamin A metabolic process(GO:0006776) |
| 0.0 | 0.2 | GO:0046415 | urate metabolic process(GO:0046415) |
| 0.0 | 0.0 | GO:0070254 | mucus secretion(GO:0070254) |
| 0.0 | 0.0 | GO:0045085 | negative regulation of interleukin-2 biosynthetic process(GO:0045085) |
| 0.0 | 0.1 | GO:0044413 | evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834) |
| 0.0 | 1.0 | GO:0006968 | cellular defense response(GO:0006968) |
| 0.0 | 0.2 | GO:0045742 | positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) positive regulation of ERBB signaling pathway(GO:1901186) |
| 0.0 | 1.2 | GO:0030041 | actin filament polymerization(GO:0030041) |
| 0.0 | 0.2 | GO:0060638 | mesenchymal-epithelial cell signaling(GO:0060638) |
| 0.0 | 0.3 | GO:0051353 | positive regulation of oxidoreductase activity(GO:0051353) |
| 0.0 | 0.0 | GO:0007635 | chemosensory behavior(GO:0007635) |
| 0.0 | 1.8 | GO:0007266 | Rho protein signal transduction(GO:0007266) |
| 0.0 | 0.1 | GO:0051290 | protein heterotetramerization(GO:0051290) |
| 0.0 | 0.1 | GO:0043984 | histone H4-K16 acetylation(GO:0043984) |
| 0.0 | 0.1 | GO:0019372 | lipoxygenase pathway(GO:0019372) |
| 0.0 | 0.2 | GO:0030388 | fructose 1,6-bisphosphate metabolic process(GO:0030388) |
| 0.0 | 0.2 | GO:0006044 | N-acetylglucosamine metabolic process(GO:0006044) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 1.8 | GO:0001891 | phagocytic cup(GO:0001891) |
| 0.2 | 1.1 | GO:0019718 | obsolete rough microsome(GO:0019718) |
| 0.1 | 1.5 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
| 0.1 | 1.2 | GO:0030130 | clathrin coat of trans-Golgi network vesicle(GO:0030130) |
| 0.1 | 0.7 | GO:0005828 | kinetochore microtubule(GO:0005828) |
| 0.1 | 0.6 | GO:0032039 | integrator complex(GO:0032039) |
| 0.0 | 0.5 | GO:0034993 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
| 0.0 | 0.7 | GO:0000242 | pericentriolar material(GO:0000242) |
| 0.0 | 1.6 | GO:0045095 | keratin filament(GO:0045095) |
| 0.0 | 2.4 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.0 | 0.4 | GO:0005832 | chaperonin-containing T-complex(GO:0005832) |
| 0.0 | 0.5 | GO:0071778 | obsolete WINAC complex(GO:0071778) |
| 0.0 | 0.4 | GO:0071203 | F-actin capping protein complex(GO:0008290) WASH complex(GO:0071203) |
| 0.0 | 0.7 | GO:0034362 | low-density lipoprotein particle(GO:0034362) |
| 0.0 | 2.2 | GO:0030667 | secretory granule membrane(GO:0030667) |
| 0.0 | 0.6 | GO:0031231 | integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231) |
| 0.0 | 0.4 | GO:0035631 | CD40 receptor complex(GO:0035631) |
| 0.0 | 0.1 | GO:0072487 | MSL complex(GO:0072487) |
| 0.0 | 1.8 | GO:0035097 | methyltransferase complex(GO:0034708) histone methyltransferase complex(GO:0035097) |
| 0.0 | 0.1 | GO:0031512 | motile primary cilium(GO:0031512) |
| 0.0 | 0.1 | GO:0031229 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453) |
| 0.0 | 0.1 | GO:0044298 | neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298) |
| 0.0 | 0.2 | GO:0031254 | uropod(GO:0001931) cell trailing edge(GO:0031254) |
| 0.0 | 0.1 | GO:0005682 | U5 snRNP(GO:0005682) |
| 0.0 | 2.9 | GO:0005938 | cell cortex(GO:0005938) |
| 0.0 | 0.7 | GO:0005884 | actin filament(GO:0005884) |
| 0.0 | 0.5 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.0 | 0.5 | GO:0016328 | lateral plasma membrane(GO:0016328) |
| 0.0 | 1.2 | GO:0016605 | PML body(GO:0016605) |
| 0.0 | 0.4 | GO:0031514 | motile cilium(GO:0031514) |
| 0.0 | 0.2 | GO:1903561 | extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561) |
| 0.0 | 0.1 | GO:0031519 | PcG protein complex(GO:0031519) |
| 0.0 | 0.1 | GO:0042587 | glycogen granule(GO:0042587) |
| 0.0 | 1.0 | GO:0009898 | cytoplasmic side of plasma membrane(GO:0009898) cytoplasmic side of membrane(GO:0098562) |
| 0.0 | 3.3 | GO:0005667 | transcription factor complex(GO:0005667) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 1.3 | GO:0019797 | procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544) |
| 0.3 | 0.9 | GO:0042610 | CD8 receptor binding(GO:0042610) |
| 0.3 | 2.5 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.2 | 1.6 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
| 0.2 | 0.8 | GO:0008486 | diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) |
| 0.1 | 0.6 | GO:0043423 | 3-phosphoinositide-dependent protein kinase binding(GO:0043423) |
| 0.1 | 1.5 | GO:0016175 | superoxide-generating NADPH oxidase activity(GO:0016175) |
| 0.1 | 3.1 | GO:0070491 | repressing transcription factor binding(GO:0070491) |
| 0.1 | 0.4 | GO:0015183 | L-aspartate transmembrane transporter activity(GO:0015183) |
| 0.1 | 0.7 | GO:0008107 | galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127) |
| 0.1 | 2.0 | GO:0042056 | chemoattractant activity(GO:0042056) |
| 0.1 | 0.9 | GO:0004568 | chitinase activity(GO:0004568) |
| 0.1 | 1.2 | GO:0030276 | clathrin binding(GO:0030276) |
| 0.1 | 0.6 | GO:0016494 | C-X-C chemokine receptor activity(GO:0016494) |
| 0.1 | 0.2 | GO:0031877 | somatostatin receptor binding(GO:0031877) |
| 0.1 | 0.3 | GO:0004852 | uroporphyrinogen-III synthase activity(GO:0004852) |
| 0.1 | 0.2 | GO:0004514 | nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514) |
| 0.1 | 0.6 | GO:0016857 | racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857) |
| 0.1 | 0.2 | GO:0004083 | bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619) |
| 0.1 | 0.5 | GO:0019237 | centromeric DNA binding(GO:0019237) |
| 0.0 | 0.4 | GO:0050682 | AF-2 domain binding(GO:0050682) |
| 0.0 | 1.3 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.0 | 0.2 | GO:0035326 | enhancer binding(GO:0035326) |
| 0.0 | 1.0 | GO:0045028 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
| 0.0 | 0.1 | GO:0008192 | RNA guanylyltransferase activity(GO:0008192) |
| 0.0 | 1.3 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.0 | 0.6 | GO:0005522 | profilin binding(GO:0005522) |
| 0.0 | 0.1 | GO:0003951 | NAD+ kinase activity(GO:0003951) |
| 0.0 | 0.1 | GO:0015254 | glycerol channel activity(GO:0015254) |
| 0.0 | 0.3 | GO:0030297 | transmembrane receptor protein tyrosine kinase activator activity(GO:0030297) |
| 0.0 | 0.3 | GO:0004300 | enoyl-CoA hydratase activity(GO:0004300) |
| 0.0 | 0.2 | GO:0045545 | syndecan binding(GO:0045545) |
| 0.0 | 3.4 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
| 0.0 | 0.6 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
| 0.0 | 0.4 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
| 0.0 | 0.1 | GO:0004980 | melanocyte-stimulating hormone receptor activity(GO:0004980) |
| 0.0 | 0.1 | GO:0004939 | beta-adrenergic receptor activity(GO:0004939) |
| 0.0 | 1.6 | GO:0002039 | p53 binding(GO:0002039) |
| 0.0 | 0.6 | GO:0051018 | protein kinase A binding(GO:0051018) |
| 0.0 | 0.7 | GO:0001972 | retinoic acid binding(GO:0001972) |
| 0.0 | 0.1 | GO:0050473 | hepoxilin-epoxide hydrolase activity(GO:0047977) arachidonate 15-lipoxygenase activity(GO:0050473) |
| 0.0 | 0.2 | GO:0031434 | mitogen-activated protein kinase kinase binding(GO:0031434) |
| 0.0 | 2.2 | GO:0003704 | obsolete specific RNA polymerase II transcription factor activity(GO:0003704) |
| 0.0 | 0.3 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, RNA polymerase II basal transcription factor binding(GO:0001083) transcription factor activity, TFIIB-class binding(GO:0001087) RNA polymerase II basal transcription factor binding(GO:0001091) TFIIB-class transcription factor binding(GO:0001093) |
| 0.0 | 0.1 | GO:0031702 | type 1 angiotensin receptor binding(GO:0031702) |
| 0.0 | 0.1 | GO:0004960 | thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961) |
| 0.0 | 1.5 | GO:0051015 | actin filament binding(GO:0051015) |
| 0.0 | 0.3 | GO:0000155 | phosphorelay sensor kinase activity(GO:0000155) |
| 0.0 | 0.7 | GO:0003705 | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705) |
| 0.0 | 0.1 | GO:0015185 | gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185) |
| 0.0 | 0.1 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
| 0.0 | 1.6 | GO:0070851 | growth factor receptor binding(GO:0070851) |
| 0.0 | 0.6 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 0.0 | 0.4 | GO:0005095 | GTPase inhibitor activity(GO:0005095) |
| 0.0 | 0.2 | GO:0051635 | obsolete bacterial cell surface binding(GO:0051635) |
| 0.0 | 0.1 | GO:0003845 | 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845) |
| 0.0 | 0.9 | GO:0003678 | DNA helicase activity(GO:0003678) |
| 0.0 | 0.1 | GO:0005499 | vitamin D binding(GO:0005499) |
| 0.0 | 1.9 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.0 | 0.6 | GO:0004629 | phospholipase C activity(GO:0004629) |
| 0.0 | 0.2 | GO:0030899 | calcium-dependent ATPase activity(GO:0030899) |
| 0.0 | 0.5 | GO:0005024 | transforming growth factor beta-activated receptor activity(GO:0005024) |
| 0.0 | 0.0 | GO:0003846 | 2-acylglycerol O-acyltransferase activity(GO:0003846) |
| 0.0 | 0.2 | GO:0019841 | retinol binding(GO:0019841) |
| 0.0 | 0.3 | GO:0016755 | transferase activity, transferring amino-acyl groups(GO:0016755) |
| 0.0 | 0.2 | GO:0004332 | fructose-bisphosphate aldolase activity(GO:0004332) |
| 0.0 | 0.2 | GO:0005123 | death receptor binding(GO:0005123) |
| 0.0 | 0.7 | GO:0004984 | olfactory receptor activity(GO:0004984) |
| 0.0 | 0.1 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
| 0.0 | 0.2 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.0 | 0.1 | GO:0004105 | choline-phosphate cytidylyltransferase activity(GO:0004105) |
| 0.0 | 0.1 | GO:0030274 | LIM domain binding(GO:0030274) |
| 0.0 | 0.1 | GO:0003747 | translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079) |
| 0.0 | 1.9 | GO:0003702 | obsolete RNA polymerase II transcription factor activity(GO:0003702) |
| 0.0 | 0.2 | GO:0030553 | cGMP binding(GO:0030553) |
| 0.0 | 0.5 | GO:0008094 | DNA-dependent ATPase activity(GO:0008094) |
| 0.0 | 0.0 | GO:0003956 | NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956) |
| 0.0 | 0.2 | GO:0019213 | deacetylase activity(GO:0019213) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 5.1 | ST_T_CELL_SIGNAL_TRANSDUCTION | T Cell Signal Transduction |
| 0.0 | 0.9 | SA_MMP_CYTOKINE_CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 0.0 | 0.6 | SA_PTEN_PATHWAY | PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate. |
| 0.0 | 0.1 | SA_TRKA_RECEPTOR | The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth. |
| 0.0 | 0.2 | ST_INTERFERON_GAMMA_PATHWAY | Interferon gamma pathway. |
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