Motif ID: RXRA_NR2F6_NR2C2
Z-value: 2.061
Transcription factors associated with RXRA_NR2F6_NR2C2:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| NR2C2 | ENSG00000177463.11 | NR2C2 |
| NR2F6 | ENSG00000160113.5 | NR2F6 |
| RXRA | ENSG00000186350.8 | RXRA |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.5 | 10.0 | GO:0010903 | negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903) |
| 1.5 | 6.1 | GO:0071364 | cellular response to epidermal growth factor stimulus(GO:0071364) |
| 0.7 | 2.8 | GO:0001969 | activation of membrane attack complex(GO:0001905) regulation of activation of membrane attack complex(GO:0001969) positive regulation of activation of membrane attack complex(GO:0001970) positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259) |
| 0.5 | 2.6 | GO:0009439 | cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440) |
| 0.4 | 4.1 | GO:0046653 | tetrahydrofolate metabolic process(GO:0046653) |
| 0.4 | 1.5 | GO:0014040 | regulation of Schwann cell differentiation(GO:0014038) positive regulation of Schwann cell differentiation(GO:0014040) |
| 0.4 | 5.0 | GO:0001522 | pseudouridine synthesis(GO:0001522) |
| 0.4 | 1.8 | GO:0003070 | age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) |
| 0.3 | 0.7 | GO:0010804 | negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804) |
| 0.3 | 1.0 | GO:0009648 | photoperiodism(GO:0009648) |
| 0.3 | 1.9 | GO:1901503 | ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503) |
| 0.3 | 1.5 | GO:0035444 | nickel cation transport(GO:0015675) vanadium ion transport(GO:0015676) ferrous iron transport(GO:0015684) lead ion transport(GO:0015692) nickel cation transmembrane transport(GO:0035444) ferrous iron import(GO:0070627) iron ion import(GO:0097286) |
| 0.3 | 1.8 | GO:0006703 | estrogen biosynthetic process(GO:0006703) |
| 0.3 | 2.6 | GO:0051918 | negative regulation of fibrinolysis(GO:0051918) |
| 0.3 | 0.8 | GO:0002575 | basophil chemotaxis(GO:0002575) |
| 0.3 | 1.0 | GO:0042866 | pyruvate biosynthetic process(GO:0042866) |
| 0.2 | 1.5 | GO:0006562 | proline catabolic process(GO:0006562) |
| 0.2 | 0.7 | GO:0032571 | response to vitamin K(GO:0032571) |
| 0.2 | 1.5 | GO:0070779 | D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779) |
| 0.2 | 1.0 | GO:0051852 | disruption by host of symbiont cells(GO:0051852) killing by host of symbiont cells(GO:0051873) |
| 0.2 | 0.8 | GO:0006391 | transcription initiation from mitochondrial promoter(GO:0006391) |
| 0.2 | 0.6 | GO:0061030 | epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030) |
| 0.2 | 1.4 | GO:0045780 | positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852) |
| 0.2 | 0.6 | GO:0090206 | negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206) |
| 0.2 | 1.2 | GO:0006561 | proline metabolic process(GO:0006560) proline biosynthetic process(GO:0006561) |
| 0.2 | 0.5 | GO:0006273 | lagging strand elongation(GO:0006273) |
| 0.2 | 1.6 | GO:0006654 | phosphatidic acid biosynthetic process(GO:0006654) |
| 0.2 | 0.8 | GO:0007614 | short-term memory(GO:0007614) |
| 0.2 | 3.1 | GO:0006957 | complement activation, alternative pathway(GO:0006957) |
| 0.2 | 0.9 | GO:0060397 | JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397) |
| 0.1 | 1.0 | GO:0007598 | blood coagulation, extrinsic pathway(GO:0007598) |
| 0.1 | 2.8 | GO:0015838 | amino-acid betaine transport(GO:0015838) carnitine transport(GO:0015879) |
| 0.1 | 1.6 | GO:0006107 | oxaloacetate metabolic process(GO:0006107) |
| 0.1 | 0.4 | GO:0043276 | anoikis(GO:0043276) |
| 0.1 | 0.7 | GO:0071699 | olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699) |
| 0.1 | 1.7 | GO:0030388 | fructose 1,6-bisphosphate metabolic process(GO:0030388) |
| 0.1 | 2.1 | GO:0071577 | zinc II ion transmembrane transport(GO:0071577) |
| 0.1 | 1.1 | GO:0046784 | viral mRNA export from host cell nucleus(GO:0046784) |
| 0.1 | 0.8 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
| 0.1 | 0.1 | GO:0046485 | ether lipid metabolic process(GO:0046485) |
| 0.1 | 0.4 | GO:0046778 | modification by virus of host mRNA processing(GO:0046778) |
| 0.1 | 0.3 | GO:0045650 | negative regulation of macrophage differentiation(GO:0045650) |
| 0.1 | 0.2 | GO:0046732 | induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by virus of host immune response(GO:0075528) |
| 0.1 | 0.3 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
| 0.1 | 1.5 | GO:0050832 | defense response to fungus(GO:0050832) |
| 0.1 | 0.3 | GO:0007028 | cytoplasm organization(GO:0007028) |
| 0.1 | 0.3 | GO:0019605 | butyrate metabolic process(GO:0019605) |
| 0.1 | 0.5 | GO:0060632 | regulation of microtubule-based movement(GO:0060632) |
| 0.1 | 0.4 | GO:0048550 | negative regulation of pinocytosis(GO:0048550) |
| 0.1 | 0.3 | GO:0034723 | DNA replication-dependent nucleosome organization(GO:0034723) |
| 0.1 | 0.7 | GO:0043951 | negative regulation of cAMP-mediated signaling(GO:0043951) |
| 0.1 | 0.4 | GO:0050957 | equilibrioception(GO:0050957) |
| 0.1 | 1.2 | GO:0006750 | glutathione biosynthetic process(GO:0006750) |
| 0.1 | 0.5 | GO:0015671 | oxygen transport(GO:0015671) |
| 0.1 | 0.8 | GO:0006027 | glycosaminoglycan catabolic process(GO:0006027) |
| 0.1 | 1.6 | GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER(GO:0006890) |
| 0.1 | 0.3 | GO:0060236 | regulation of mitotic spindle organization(GO:0060236) |
| 0.1 | 0.4 | GO:0070245 | positive regulation of thymocyte apoptotic process(GO:0070245) |
| 0.1 | 1.0 | GO:0018298 | protein-chromophore linkage(GO:0018298) |
| 0.1 | 0.2 | GO:0042760 | very long-chain fatty acid catabolic process(GO:0042760) |
| 0.1 | 0.2 | GO:0032486 | Rap protein signal transduction(GO:0032486) |
| 0.1 | 0.3 | GO:0034371 | chylomicron remodeling(GO:0034371) |
| 0.1 | 0.3 | GO:0007095 | mitotic G2 DNA damage checkpoint(GO:0007095) |
| 0.1 | 1.1 | GO:0048024 | regulation of mRNA splicing, via spliceosome(GO:0048024) |
| 0.1 | 0.3 | GO:0046952 | ketone body catabolic process(GO:0046952) |
| 0.1 | 0.8 | GO:0006400 | tRNA modification(GO:0006400) |
| 0.1 | 0.4 | GO:0006600 | creatine metabolic process(GO:0006600) |
| 0.1 | 1.3 | GO:0051881 | regulation of mitochondrial membrane potential(GO:0051881) |
| 0.1 | 0.9 | GO:0000038 | very long-chain fatty acid metabolic process(GO:0000038) |
| 0.0 | 3.6 | GO:0006821 | chloride transport(GO:0006821) |
| 0.0 | 2.0 | GO:0050918 | positive chemotaxis(GO:0050918) |
| 0.0 | 0.1 | GO:0070734 | histone H3-K27 methylation(GO:0070734) |
| 0.0 | 0.2 | GO:1903301 | regulation of glucokinase activity(GO:0033131) positive regulation of glucokinase activity(GO:0033133) regulation of hexokinase activity(GO:1903299) positive regulation of hexokinase activity(GO:1903301) |
| 0.0 | 0.1 | GO:0044240 | multicellular organism lipid catabolic process(GO:0044240) |
| 0.0 | 1.4 | GO:0010595 | positive regulation of endothelial cell migration(GO:0010595) |
| 0.0 | 0.7 | GO:1902591 | vesicle coating(GO:0006901) vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114) single-organism membrane budding(GO:1902591) |
| 0.0 | 1.9 | GO:0050728 | negative regulation of inflammatory response(GO:0050728) |
| 0.0 | 0.2 | GO:0035434 | copper ion transmembrane transport(GO:0035434) |
| 0.0 | 0.4 | GO:0060760 | positive regulation of response to cytokine stimulus(GO:0060760) |
| 0.0 | 0.2 | GO:0002313 | mature B cell differentiation involved in immune response(GO:0002313) |
| 0.0 | 1.2 | GO:0006730 | one-carbon metabolic process(GO:0006730) |
| 0.0 | 1.9 | GO:0008156 | negative regulation of DNA replication(GO:0008156) |
| 0.0 | 0.2 | GO:0045163 | clustering of voltage-gated potassium channels(GO:0045163) |
| 0.0 | 1.0 | GO:0022904 | respiratory electron transport chain(GO:0022904) |
| 0.0 | 0.2 | GO:0051299 | centrosome separation(GO:0051299) |
| 0.0 | 0.7 | GO:0032012 | regulation of ARF protein signal transduction(GO:0032012) |
| 0.0 | 3.0 | GO:0008360 | regulation of cell shape(GO:0008360) |
| 0.0 | 1.3 | GO:0015914 | phospholipid transport(GO:0015914) |
| 0.0 | 0.1 | GO:0003056 | regulation of vascular smooth muscle contraction(GO:0003056) |
| 0.0 | 1.6 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
| 0.0 | 0.4 | GO:0006998 | nuclear envelope organization(GO:0006998) |
| 0.0 | 0.2 | GO:0019509 | L-methionine biosynthetic process from methylthioadenosine(GO:0019509) |
| 0.0 | 0.4 | GO:0006825 | copper ion transport(GO:0006825) |
| 0.0 | 0.4 | GO:0001893 | maternal placenta development(GO:0001893) |
| 0.0 | 1.1 | GO:0043154 | negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154) |
| 0.0 | 0.4 | GO:0031498 | nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986) |
| 0.0 | 0.3 | GO:0034331 | cell junction maintenance(GO:0034331) cell-cell junction maintenance(GO:0045217) |
| 0.0 | 0.2 | GO:0017183 | peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) |
| 0.0 | 0.1 | GO:0071679 | facial nucleus development(GO:0021754) cell proliferation in midbrain(GO:0033278) commissural neuron axon guidance(GO:0071679) |
| 0.0 | 0.1 | GO:0071436 | sodium ion export(GO:0071436) |
| 0.0 | 1.3 | GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184) |
| 0.0 | 0.2 | GO:0021978 | telencephalon regionalization(GO:0021978) |
| 0.0 | 0.3 | GO:0060124 | positive regulation of growth hormone secretion(GO:0060124) |
| 0.0 | 0.7 | GO:0008334 | histone mRNA metabolic process(GO:0008334) |
| 0.0 | 0.6 | GO:0045730 | respiratory burst(GO:0045730) |
| 0.0 | 0.2 | GO:0060523 | prostate epithelial cord elongation(GO:0060523) |
| 0.0 | 0.5 | GO:0030219 | megakaryocyte differentiation(GO:0030219) |
| 0.0 | 3.3 | GO:0007018 | microtubule-based movement(GO:0007018) |
| 0.0 | 0.1 | GO:0008543 | fibroblast growth factor receptor signaling pathway(GO:0008543) cellular response to fibroblast growth factor stimulus(GO:0044344) response to fibroblast growth factor(GO:0071774) |
| 0.0 | 1.0 | GO:0021549 | cerebellum development(GO:0021549) |
| 0.0 | 0.1 | GO:0031034 | skeletal muscle myosin thick filament assembly(GO:0030241) myosin filament assembly(GO:0031034) striated muscle myosin thick filament assembly(GO:0071688) |
| 0.0 | 0.1 | GO:0060152 | peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152) |
| 0.0 | 2.5 | GO:0002576 | platelet degranulation(GO:0002576) |
| 0.0 | 0.3 | GO:0046415 | urate metabolic process(GO:0046415) |
| 0.0 | 1.6 | GO:0035264 | multicellular organism growth(GO:0035264) |
| 0.0 | 0.6 | GO:0035338 | long-chain fatty-acyl-CoA metabolic process(GO:0035336) long-chain fatty-acyl-CoA biosynthetic process(GO:0035338) |
| 0.0 | 0.1 | GO:0032494 | response to peptidoglycan(GO:0032494) |
| 0.0 | 0.0 | GO:0060398 | regulation of growth hormone receptor signaling pathway(GO:0060398) |
| 0.0 | 0.5 | GO:0007194 | negative regulation of adenylate cyclase activity(GO:0007194) negative regulation of cyclase activity(GO:0031280) negative regulation of lyase activity(GO:0051350) |
| 0.0 | 0.2 | GO:0060255 | regulation of macromolecule metabolic process(GO:0060255) |
| 0.0 | 0.3 | GO:0030212 | hyaluronan metabolic process(GO:0030212) |
| 0.0 | 0.8 | GO:0006886 | intracellular protein transport(GO:0006886) |
| 0.0 | 0.2 | GO:0048070 | regulation of developmental pigmentation(GO:0048070) |
| 0.0 | 0.5 | GO:0050873 | brown fat cell differentiation(GO:0050873) |
| 0.0 | 0.1 | GO:0030252 | growth hormone secretion(GO:0030252) |
| 0.0 | 1.0 | GO:0034339 | obsolete regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor(GO:0034339) |
| 0.0 | 0.2 | GO:1900087 | traversing start control point of mitotic cell cycle(GO:0007089) positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) positive regulation of cell cycle G1/S phase transition(GO:1902808) |
| 0.0 | 0.1 | GO:0060744 | thelarche(GO:0042695) development of secondary female sexual characteristics(GO:0046543) mammary gland branching involved in thelarche(GO:0060744) |
| 0.0 | 0.3 | GO:0032008 | positive regulation of TOR signaling(GO:0032008) |
| 0.0 | 0.2 | GO:0019221 | cytokine-mediated signaling pathway(GO:0019221) cellular response to cytokine stimulus(GO:0071345) |
| 0.0 | 0.4 | GO:0051225 | spindle assembly(GO:0051225) |
| 0.0 | 0.1 | GO:0008228 | opsonization(GO:0008228) |
| 0.0 | 0.9 | GO:0006695 | cholesterol biosynthetic process(GO:0006695) |
| 0.0 | 0.3 | GO:0006098 | pentose-phosphate shunt(GO:0006098) glyceraldehyde-3-phosphate metabolic process(GO:0019682) |
| 0.0 | 0.3 | GO:0043097 | pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097) |
| 0.0 | 0.2 | GO:0015937 | coenzyme A biosynthetic process(GO:0015937) |
| 0.0 | 0.1 | GO:0051365 | cellular response to potassium ion starvation(GO:0051365) |
| 0.0 | 0.5 | GO:0050868 | negative regulation of T cell activation(GO:0050868) negative regulation of leukocyte cell-cell adhesion(GO:1903038) |
| 0.0 | 0.1 | GO:0033137 | negative regulation of peptidyl-serine phosphorylation(GO:0033137) |
| 0.0 | 0.1 | GO:0006000 | fructose metabolic process(GO:0006000) |
| 0.0 | 0.6 | GO:0002687 | positive regulation of leukocyte migration(GO:0002687) |
| 0.0 | 0.4 | GO:0060056 | mammary gland involution(GO:0060056) |
| 0.0 | 0.1 | GO:0006669 | sphinganine-1-phosphate biosynthetic process(GO:0006669) |
| 0.0 | 0.5 | GO:0007398 | ectoderm development(GO:0007398) |
| 0.0 | 0.6 | GO:0030325 | adrenal gland development(GO:0030325) |
| 0.0 | 2.9 | GO:0006470 | protein dephosphorylation(GO:0006470) |
| 0.0 | 0.2 | GO:0006613 | cotranslational protein targeting to membrane(GO:0006613) |
| 0.0 | 0.3 | GO:0043101 | purine-containing compound salvage(GO:0043101) |
| 0.0 | 0.2 | GO:0000301 | retrograde transport, vesicle recycling within Golgi(GO:0000301) auditory receptor cell differentiation(GO:0042491) |
| 0.0 | 0.2 | GO:0051597 | response to methylmercury(GO:0051597) |
| 0.0 | 0.8 | GO:0006096 | glycolytic process(GO:0006096) ATP generation from ADP(GO:0006757) |
| 0.0 | 0.7 | GO:0006406 | mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427) |
| 0.0 | 0.4 | GO:0007051 | spindle organization(GO:0007051) |
| 0.0 | 0.5 | GO:0002456 | T cell mediated immunity(GO:0002456) |
| 0.0 | 1.0 | GO:0030198 | extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062) |
| 0.0 | 0.3 | GO:0030866 | cortical actin cytoskeleton organization(GO:0030866) |
| 0.0 | 1.6 | GO:0007266 | Rho protein signal transduction(GO:0007266) |
| 0.0 | 1.9 | GO:0031018 | endocrine pancreas development(GO:0031018) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.0 | 1.0 | GO:0005624 | obsolete membrane fraction(GO:0005624) |
| 0.6 | 10.0 | GO:0034366 | spherical high-density lipoprotein particle(GO:0034366) |
| 0.3 | 1.5 | GO:0070826 | paraferritin complex(GO:0070826) |
| 0.2 | 1.4 | GO:0045179 | apical cortex(GO:0045179) |
| 0.2 | 0.5 | GO:0031838 | haptoglobin-hemoglobin complex(GO:0031838) |
| 0.2 | 1.1 | GO:0000445 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
| 0.1 | 1.5 | GO:0030673 | axolemma(GO:0030673) |
| 0.1 | 1.7 | GO:1903561 | extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561) |
| 0.1 | 5.9 | GO:0005902 | microvillus(GO:0005902) |
| 0.1 | 1.1 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.1 | 0.9 | GO:0042825 | TAP complex(GO:0042825) |
| 0.1 | 1.3 | GO:0016442 | RISC complex(GO:0016442) RNAi effector complex(GO:0031332) |
| 0.1 | 0.9 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 0.1 | 1.3 | GO:0031233 | intrinsic component of external side of plasma membrane(GO:0031233) |
| 0.1 | 7.3 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 0.1 | 0.7 | GO:0005683 | U7 snRNP(GO:0005683) |
| 0.1 | 0.3 | GO:0043512 | inhibin complex(GO:0043511) inhibin A complex(GO:0043512) |
| 0.1 | 2.1 | GO:0030057 | desmosome(GO:0030057) |
| 0.1 | 0.7 | GO:0042598 | obsolete vesicular fraction(GO:0042598) |
| 0.1 | 1.0 | GO:0035631 | CD40 receptor complex(GO:0035631) |
| 0.1 | 0.5 | GO:0042575 | DNA polymerase complex(GO:0042575) |
| 0.1 | 0.2 | GO:0071256 | Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256) |
| 0.1 | 1.4 | GO:0031519 | PcG protein complex(GO:0031519) |
| 0.1 | 0.2 | GO:0031232 | extrinsic component of external side of plasma membrane(GO:0031232) |
| 0.1 | 0.4 | GO:0070761 | pre-snoRNP complex(GO:0070761) |
| 0.0 | 0.4 | GO:0070652 | HAUS complex(GO:0070652) |
| 0.0 | 2.5 | GO:0005884 | actin filament(GO:0005884) |
| 0.0 | 0.2 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.0 | 0.7 | GO:0030127 | COPII vesicle coat(GO:0030127) |
| 0.0 | 3.6 | GO:0034707 | chloride channel complex(GO:0034707) |
| 0.0 | 0.6 | GO:0012507 | ER to Golgi transport vesicle membrane(GO:0012507) |
| 0.0 | 1.5 | GO:0031526 | brush border membrane(GO:0031526) |
| 0.0 | 0.4 | GO:0030126 | COPI vesicle coat(GO:0030126) |
| 0.0 | 12.8 | GO:0005759 | mitochondrial matrix(GO:0005759) |
| 0.0 | 0.2 | GO:0005744 | mitochondrial inner membrane presequence translocase complex(GO:0005744) |
| 0.0 | 1.6 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 0.0 | 0.2 | GO:0033268 | node of Ranvier(GO:0033268) |
| 0.0 | 0.6 | GO:0019861 | obsolete flagellum(GO:0019861) |
| 0.0 | 3.7 | GO:0042579 | peroxisome(GO:0005777) microbody(GO:0042579) |
| 0.0 | 0.5 | GO:0016585 | obsolete chromatin remodeling complex(GO:0016585) |
| 0.0 | 0.2 | GO:0017119 | Golgi transport complex(GO:0017119) |
| 0.0 | 0.1 | GO:0009279 | cell outer membrane(GO:0009279) |
| 0.0 | 0.1 | GO:0031371 | ubiquitin conjugating enzyme complex(GO:0031371) |
| 0.0 | 0.6 | GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment(GO:0005793) |
| 0.0 | 0.5 | GO:0016514 | SWI/SNF complex(GO:0016514) |
| 0.0 | 0.3 | GO:0000808 | origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664) |
| 0.0 | 0.1 | GO:0045323 | interleukin-1 receptor complex(GO:0045323) |
| 0.0 | 0.3 | GO:0042627 | chylomicron(GO:0042627) |
| 0.0 | 0.1 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
| 0.0 | 1.2 | GO:0000794 | condensed nuclear chromosome(GO:0000794) |
| 0.0 | 0.5 | GO:0042612 | MHC class I protein complex(GO:0042612) |
| 0.0 | 1.8 | GO:0005643 | nuclear pore(GO:0005643) |
| 0.0 | 1.5 | GO:0030027 | lamellipodium(GO:0030027) |
| 0.0 | 0.2 | GO:0008091 | spectrin(GO:0008091) |
| 0.0 | 0.5 | GO:0001669 | acrosomal vesicle(GO:0001669) |
| 0.0 | 0.9 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.0 | 0.3 | GO:0001772 | immunological synapse(GO:0001772) |
| 0.0 | 0.7 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
| 0.0 | 0.2 | GO:0032420 | stereocilium(GO:0032420) |
| 0.0 | 0.1 | GO:0043198 | dendritic shaft(GO:0043198) |
| 0.0 | 1.5 | GO:0000785 | chromatin(GO:0000785) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.5 | 10.0 | GO:0070653 | high-density lipoprotein particle receptor binding(GO:0070653) |
| 1.7 | 5.0 | GO:0004730 | pseudouridylate synthase activity(GO:0004730) |
| 0.7 | 4.1 | GO:0016647 | oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647) |
| 0.6 | 2.4 | GO:0016784 | 3-mercaptopyruvate sulfurtransferase activity(GO:0016784) |
| 0.6 | 8.4 | GO:0004017 | adenylate kinase activity(GO:0004017) |
| 0.4 | 1.3 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
| 0.4 | 1.2 | GO:0004613 | phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613) |
| 0.4 | 1.5 | GO:0004657 | proline dehydrogenase activity(GO:0004657) |
| 0.4 | 1.4 | GO:0030292 | protein tyrosine kinase inhibitor activity(GO:0030292) |
| 0.4 | 1.1 | GO:0010861 | thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375) |
| 0.3 | 3.2 | GO:0001848 | complement binding(GO:0001848) |
| 0.3 | 1.3 | GO:0004525 | ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296) |
| 0.3 | 1.5 | GO:0015087 | cobalt ion transmembrane transporter activity(GO:0015087) ferrous iron transmembrane transporter activity(GO:0015093) lead ion transmembrane transporter activity(GO:0015094) nickel cation transmembrane transporter activity(GO:0015099) vanadium ion transmembrane transporter activity(GO:0015100) chromium ion transmembrane transporter activity(GO:0070835) |
| 0.2 | 7.1 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
| 0.2 | 1.5 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
| 0.2 | 0.7 | GO:0008525 | phosphatidylcholine transporter activity(GO:0008525) |
| 0.2 | 1.2 | GO:0004735 | pyrroline-5-carboxylate reductase activity(GO:0004735) |
| 0.2 | 0.9 | GO:0015433 | peptide antigen-transporting ATPase activity(GO:0015433) |
| 0.2 | 0.6 | GO:0008192 | RNA guanylyltransferase activity(GO:0008192) |
| 0.2 | 0.8 | GO:0004566 | beta-glucuronidase activity(GO:0004566) |
| 0.2 | 0.6 | GO:0015142 | citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142) |
| 0.2 | 1.4 | GO:0004784 | superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721) |
| 0.2 | 1.0 | GO:0030955 | potassium ion binding(GO:0030955) |
| 0.2 | 1.8 | GO:0047035 | testosterone dehydrogenase (NAD+) activity(GO:0047035) |
| 0.2 | 0.3 | GO:0003989 | acetyl-CoA carboxylase activity(GO:0003989) |
| 0.2 | 1.7 | GO:0004332 | fructose-bisphosphate aldolase activity(GO:0004332) |
| 0.2 | 0.8 | GO:0043184 | vascular endothelial growth factor receptor 2 binding(GO:0043184) |
| 0.1 | 1.5 | GO:0009374 | biotin binding(GO:0009374) |
| 0.1 | 0.7 | GO:0004591 | oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591) |
| 0.1 | 0.4 | GO:0016531 | copper chaperone activity(GO:0016531) |
| 0.1 | 0.7 | GO:0004095 | carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416) |
| 0.1 | 1.9 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
| 0.1 | 3.0 | GO:0008430 | selenium binding(GO:0008430) |
| 0.1 | 1.6 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617) |
| 0.1 | 0.5 | GO:0030881 | beta-2-microglobulin binding(GO:0030881) |
| 0.1 | 2.1 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.1 | 0.3 | GO:0017150 | tRNA dihydrouridine synthase activity(GO:0017150) |
| 0.1 | 0.2 | GO:0005375 | copper ion transmembrane transporter activity(GO:0005375) |
| 0.1 | 0.3 | GO:0015361 | low-affinity sodium:dicarboxylate symporter activity(GO:0015361) |
| 0.1 | 1.5 | GO:0004887 | thyroid hormone receptor activity(GO:0004887) |
| 0.1 | 0.4 | GO:0032810 | sterol response element binding(GO:0032810) |
| 0.1 | 4.7 | GO:0002020 | protease binding(GO:0002020) |
| 0.1 | 0.9 | GO:0003988 | acetyl-CoA C-acyltransferase activity(GO:0003988) |
| 0.1 | 0.6 | GO:0016802 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
| 0.1 | 0.3 | GO:0003858 | 3-hydroxybutyrate dehydrogenase activity(GO:0003858) |
| 0.1 | 0.5 | GO:0001641 | group II metabotropic glutamate receptor activity(GO:0001641) |
| 0.1 | 1.5 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.1 | 0.4 | GO:0004111 | creatine kinase activity(GO:0004111) |
| 0.1 | 0.2 | GO:0004792 | thiosulfate sulfurtransferase activity(GO:0004792) |
| 0.1 | 0.2 | GO:0017129 | triglyceride binding(GO:0017129) |
| 0.1 | 2.0 | GO:0070491 | repressing transcription factor binding(GO:0070491) |
| 0.1 | 4.6 | GO:0005507 | copper ion binding(GO:0005507) |
| 0.1 | 0.5 | GO:0008296 | 3'-5'-exodeoxyribonuclease activity(GO:0008296) |
| 0.1 | 1.7 | GO:0042056 | chemoattractant activity(GO:0042056) |
| 0.1 | 0.9 | GO:0051635 | obsolete bacterial cell surface binding(GO:0051635) |
| 0.1 | 0.1 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 0.1 | 2.7 | GO:0042169 | SH2 domain binding(GO:0042169) |
| 0.1 | 0.2 | GO:0017099 | very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099) |
| 0.1 | 0.2 | GO:0015217 | purine ribonucleotide transmembrane transporter activity(GO:0005346) ATP transmembrane transporter activity(GO:0005347) ATP:ADP antiporter activity(GO:0005471) ADP transmembrane transporter activity(GO:0015217) |
| 0.1 | 0.2 | GO:0047045 | testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045) |
| 0.1 | 0.3 | GO:0034711 | inhibin binding(GO:0034711) |
| 0.1 | 0.2 | GO:0032038 | myosin II heavy chain binding(GO:0032038) |
| 0.1 | 0.3 | GO:0004427 | inorganic diphosphatase activity(GO:0004427) |
| 0.0 | 2.5 | GO:0003823 | antigen binding(GO:0003823) |
| 0.0 | 0.3 | GO:0016681 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
| 0.0 | 0.7 | GO:0016846 | carbon-sulfur lyase activity(GO:0016846) |
| 0.0 | 0.4 | GO:0031996 | thioesterase binding(GO:0031996) |
| 0.0 | 0.1 | GO:0046976 | histone methyltransferase activity (H3-K27 specific)(GO:0046976) |
| 0.0 | 0.6 | GO:0060590 | ATPase regulator activity(GO:0060590) |
| 0.0 | 0.2 | GO:0008466 | glycogenin glucosyltransferase activity(GO:0008466) |
| 0.0 | 0.1 | GO:0004771 | sterol esterase activity(GO:0004771) |
| 0.0 | 0.7 | GO:0004190 | aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001) |
| 0.0 | 0.5 | GO:0048531 | beta-1,3-galactosyltransferase activity(GO:0048531) |
| 0.0 | 0.9 | GO:0004467 | long-chain fatty acid-CoA ligase activity(GO:0004467) acid-thiol ligase activity(GO:0016878) |
| 0.0 | 3.2 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.0 | 0.1 | GO:0004321 | fatty-acyl-CoA synthase activity(GO:0004321) |
| 0.0 | 0.5 | GO:0005344 | oxygen transporter activity(GO:0005344) |
| 0.0 | 0.7 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
| 0.0 | 0.3 | GO:0004849 | uridine kinase activity(GO:0004849) |
| 0.0 | 0.3 | GO:0005402 | sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) |
| 0.0 | 0.6 | GO:0042809 | vitamin D receptor binding(GO:0042809) |
| 0.0 | 0.2 | GO:0017163 | obsolete basal transcription repressor activity(GO:0017163) |
| 0.0 | 1.3 | GO:0032934 | sterol binding(GO:0032934) |
| 0.0 | 0.8 | GO:0005095 | GTPase inhibitor activity(GO:0005095) |
| 0.0 | 0.8 | GO:0000049 | tRNA binding(GO:0000049) |
| 0.0 | 3.6 | GO:0005254 | chloride channel activity(GO:0005254) |
| 0.0 | 0.1 | GO:0003870 | 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749) |
| 0.0 | 0.2 | GO:0008967 | phosphoglycolate phosphatase activity(GO:0008967) |
| 0.0 | 0.3 | GO:0003876 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
| 0.0 | 0.2 | GO:0050508 | glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508) |
| 0.0 | 0.7 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.0 | 0.7 | GO:0043499 | obsolete eukaryotic cell surface binding(GO:0043499) |
| 0.0 | 2.0 | GO:0030165 | PDZ domain binding(GO:0030165) |
| 0.0 | 0.2 | GO:0070095 | fructose-6-phosphate binding(GO:0070095) |
| 0.0 | 0.6 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.0 | 0.3 | GO:0003688 | DNA replication origin binding(GO:0003688) |
| 0.0 | 0.1 | GO:0031432 | titin binding(GO:0031432) |
| 0.0 | 0.1 | GO:0042132 | fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132) |
| 0.0 | 0.7 | GO:0051087 | chaperone binding(GO:0051087) |
| 0.0 | 0.1 | GO:0030156 | benzodiazepine receptor binding(GO:0030156) |
| 0.0 | 0.1 | GO:0004167 | dopachrome isomerase activity(GO:0004167) D-dopachrome decarboxylase activity(GO:0033981) |
| 0.0 | 2.3 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
| 0.0 | 0.4 | GO:0030275 | LRR domain binding(GO:0030275) |
| 0.0 | 0.3 | GO:0003995 | acyl-CoA dehydrogenase activity(GO:0003995) |
| 0.0 | 4.1 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.0 | 1.7 | GO:0016765 | transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765) |
| 0.0 | 0.1 | GO:0034594 | phosphatidylinositol trisphosphate phosphatase activity(GO:0034594) |
| 0.0 | 0.3 | GO:0016861 | intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861) |
| 0.0 | 0.1 | GO:0004102 | choline O-acetyltransferase activity(GO:0004102) |
| 0.0 | 0.6 | GO:0004385 | guanylate kinase activity(GO:0004385) |
| 0.0 | 0.2 | GO:0030284 | estrogen receptor activity(GO:0030284) estrogen response element binding(GO:0034056) |
| 0.0 | 0.3 | GO:0004559 | alpha-mannosidase activity(GO:0004559) |
| 0.0 | 0.1 | GO:0017050 | sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050) |
| 0.0 | 3.6 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.0 | 0.1 | GO:0004704 | NF-kappaB-inducing kinase activity(GO:0004704) |
| 0.0 | 1.2 | GO:0019903 | protein phosphatase binding(GO:0019903) |
| 0.0 | 0.8 | GO:0003899 | DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062) |
| 0.0 | 0.4 | GO:0005487 | nucleocytoplasmic transporter activity(GO:0005487) |
| 0.0 | 0.0 | GO:0045030 | UTP-activated nucleotide receptor activity(GO:0045030) |
| 0.0 | 0.5 | GO:0051219 | phosphoprotein binding(GO:0051219) |
| 0.0 | 0.6 | GO:0008601 | protein phosphatase type 2A regulator activity(GO:0008601) |
| 0.0 | 0.1 | GO:0016714 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714) |
| 0.0 | 0.0 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
| 0.0 | 0.6 | GO:0008235 | metalloexopeptidase activity(GO:0008235) |
| 0.0 | 1.4 | GO:0008201 | heparin binding(GO:0008201) |
| 0.0 | 1.4 | GO:0005179 | hormone activity(GO:0005179) |
| 0.0 | 0.4 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.0 | 1.1 | GO:0008094 | DNA-dependent ATPase activity(GO:0008094) |
| 0.0 | 0.0 | GO:0004967 | glucagon receptor activity(GO:0004967) |
| 0.0 | 0.2 | GO:0016888 | endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888) |
| 0.0 | 0.2 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
| 0.0 | 0.2 | GO:0016831 | carboxy-lyase activity(GO:0016831) |
| 0.0 | 0.1 | GO:0004090 | carbonyl reductase (NADPH) activity(GO:0004090) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.9 | ST_ERK1_ERK2_MAPK_PATHWAY | ERK1/ERK2 MAPK Pathway |
| 0.0 | 0.9 | ST_STAT3_PATHWAY | STAT3 Pathway |
| 0.0 | 0.6 | SA_CASPASE_CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
| 0.0 | 0.4 | SIG_CHEMOTAXIS | Genes related to chemotaxis |
| 0.0 | 1.2 | SIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES | Genes related to PIP3 signaling in B lymphocytes |
| 0.0 | 0.2 | SA_G2_AND_M_PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
| 0.0 | 0.6 | ST_P38_MAPK_PATHWAY | p38 MAPK Pathway |
|
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