Motif ID: SHOX2_HOXC5
Z-value: 1.659
Transcription factors associated with SHOX2_HOXC5:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| HOXC5 | ENSG00000172789.3 | HOXC5 |
| SHOX2 | ENSG00000168779.15 | SHOX2 |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.7 | 10.2 | GO:0006880 | intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577) |
| 0.7 | 2.9 | GO:0043128 | regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128) |
| 0.7 | 7.5 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
| 0.6 | 1.7 | GO:0030205 | dermatan sulfate metabolic process(GO:0030205) dermatan sulfate biosynthetic process(GO:0030208) |
| 0.5 | 1.6 | GO:0051255 | spindle midzone assembly(GO:0051255) meiotic spindle midzone assembly(GO:0051257) |
| 0.4 | 1.5 | GO:0042262 | DNA protection(GO:0042262) |
| 0.4 | 1.8 | GO:0007095 | blastocyst growth(GO:0001832) mitotic G2 DNA damage checkpoint(GO:0007095) |
| 0.3 | 2.7 | GO:0045647 | negative regulation of erythrocyte differentiation(GO:0045647) |
| 0.3 | 0.9 | GO:0070886 | positive regulation of calcineurin-NFAT signaling cascade(GO:0070886) |
| 0.3 | 0.9 | GO:0010273 | regulation of oxidative phosphorylation(GO:0002082) detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169) |
| 0.2 | 1.0 | GO:0019371 | cyclooxygenase pathway(GO:0019371) |
| 0.2 | 1.4 | GO:0006772 | thiamine metabolic process(GO:0006772) |
| 0.2 | 1.4 | GO:0008228 | opsonization(GO:0008228) |
| 0.2 | 1.5 | GO:0016584 | nucleosome positioning(GO:0016584) |
| 0.2 | 0.6 | GO:0051661 | maintenance of centrosome location(GO:0051661) |
| 0.2 | 0.8 | GO:0050965 | detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965) |
| 0.2 | 0.4 | GO:0051097 | negative regulation of helicase activity(GO:0051097) |
| 0.2 | 1.9 | GO:0006975 | DNA damage induced protein phosphorylation(GO:0006975) |
| 0.2 | 0.5 | GO:0002431 | Fc receptor mediated stimulatory signaling pathway(GO:0002431) regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369) |
| 0.2 | 0.8 | GO:0006436 | tryptophanyl-tRNA aminoacylation(GO:0006436) |
| 0.2 | 1.8 | GO:0006002 | fructose 6-phosphate metabolic process(GO:0006002) |
| 0.2 | 2.2 | GO:1901797 | negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797) |
| 0.2 | 2.4 | GO:0033687 | osteoblast proliferation(GO:0033687) |
| 0.2 | 1.1 | GO:0043415 | positive regulation of skeletal muscle tissue regeneration(GO:0043415) regulation of skeletal muscle tissue regeneration(GO:0043416) |
| 0.2 | 0.6 | GO:1902414 | protein localization to adherens junction(GO:0071896) protein localization to cell junction(GO:1902414) |
| 0.2 | 0.5 | GO:0034036 | purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428) |
| 0.1 | 0.4 | GO:0006478 | peptidyl-tyrosine sulfation(GO:0006478) |
| 0.1 | 0.7 | GO:0015722 | canalicular bile acid transport(GO:0015722) |
| 0.1 | 2.7 | GO:0070206 | protein trimerization(GO:0070206) |
| 0.1 | 0.3 | GO:0019731 | antibacterial humoral response(GO:0019731) |
| 0.1 | 0.4 | GO:0006427 | histidyl-tRNA aminoacylation(GO:0006427) |
| 0.1 | 0.8 | GO:0002903 | negative regulation of B cell apoptotic process(GO:0002903) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192) |
| 0.1 | 2.1 | GO:0032814 | regulation of natural killer cell activation(GO:0032814) |
| 0.1 | 0.7 | GO:0033119 | negative regulation of RNA splicing(GO:0033119) |
| 0.1 | 0.7 | GO:0042693 | muscle cell fate commitment(GO:0042693) |
| 0.1 | 2.6 | GO:0002504 | antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504) |
| 0.1 | 0.5 | GO:0061032 | visceral serous pericardium development(GO:0061032) |
| 0.1 | 0.2 | GO:0050942 | positive regulation of melanocyte differentiation(GO:0045636) positive regulation of pigment cell differentiation(GO:0050942) |
| 0.1 | 0.6 | GO:0051045 | negative regulation of membrane protein ectodomain proteolysis(GO:0051045) |
| 0.1 | 0.7 | GO:0034616 | response to laminar fluid shear stress(GO:0034616) |
| 0.1 | 0.8 | GO:0016098 | monoterpenoid metabolic process(GO:0016098) |
| 0.1 | 0.4 | GO:0010700 | negative regulation of norepinephrine secretion(GO:0010700) |
| 0.1 | 0.6 | GO:0044413 | evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834) |
| 0.1 | 0.3 | GO:0019695 | choline metabolic process(GO:0019695) |
| 0.1 | 1.0 | GO:0097435 | extracellular fibril organization(GO:0043206) fibril organization(GO:0097435) |
| 0.1 | 0.3 | GO:0046520 | diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520) |
| 0.1 | 1.2 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 0.1 | 1.1 | GO:1902622 | regulation of neutrophil chemotaxis(GO:0090022) regulation of neutrophil migration(GO:1902622) |
| 0.1 | 0.6 | GO:0033145 | positive regulation of intracellular steroid hormone receptor signaling pathway(GO:0033145) |
| 0.1 | 0.2 | GO:0051451 | myoblast migration(GO:0051451) |
| 0.1 | 0.3 | GO:0051102 | DNA ligation involved in DNA recombination(GO:0051102) |
| 0.1 | 0.7 | GO:0044245 | polysaccharide digestion(GO:0044245) |
| 0.1 | 1.7 | GO:0006359 | regulation of transcription from RNA polymerase III promoter(GO:0006359) |
| 0.1 | 0.4 | GO:0045103 | intermediate filament-based process(GO:0045103) |
| 0.1 | 0.4 | GO:0043402 | glucocorticoid mediated signaling pathway(GO:0043402) |
| 0.1 | 0.2 | GO:0010966 | regulation of phosphate transport(GO:0010966) |
| 0.1 | 0.7 | GO:0010507 | negative regulation of autophagy(GO:0010507) |
| 0.1 | 0.3 | GO:0060084 | synaptic transmission involved in micturition(GO:0060084) |
| 0.1 | 2.2 | GO:0030224 | monocyte differentiation(GO:0030224) |
| 0.1 | 1.4 | GO:0043623 | cellular protein complex assembly(GO:0043623) |
| 0.1 | 2.2 | GO:0033209 | tumor necrosis factor-mediated signaling pathway(GO:0033209) |
| 0.1 | 0.2 | GO:0006348 | chromatin silencing at telomere(GO:0006348) |
| 0.1 | 0.4 | GO:0019985 | translesion synthesis(GO:0019985) |
| 0.1 | 0.1 | GO:0003056 | regulation of vascular smooth muscle contraction(GO:0003056) |
| 0.1 | 0.2 | GO:0010430 | ethanol catabolic process(GO:0006068) fatty acid omega-oxidation(GO:0010430) |
| 0.1 | 1.1 | GO:0009312 | oligosaccharide biosynthetic process(GO:0009312) |
| 0.1 | 0.6 | GO:0030502 | negative regulation of bone mineralization(GO:0030502) |
| 0.1 | 0.4 | GO:0032527 | retrograde protein transport, ER to cytosol(GO:0030970) protein exit from endoplasmic reticulum(GO:0032527) |
| 0.1 | 0.9 | GO:1904031 | positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031) |
| 0.1 | 1.1 | GO:0006700 | C21-steroid hormone biosynthetic process(GO:0006700) |
| 0.1 | 0.4 | GO:0072207 | metanephric tubule development(GO:0072170) metanephric epithelium development(GO:0072207) metanephric nephron tubule development(GO:0072234) metanephric nephron epithelium development(GO:0072243) |
| 0.1 | 0.1 | GO:0045591 | negative regulation of chronic inflammatory response(GO:0002677) positive regulation of regulatory T cell differentiation(GO:0045591) |
| 0.1 | 0.3 | GO:0010457 | centriole-centriole cohesion(GO:0010457) |
| 0.1 | 0.2 | GO:0010836 | negative regulation of protein ADP-ribosylation(GO:0010836) negative regulation of protein glycosylation(GO:0060051) |
| 0.1 | 0.4 | GO:0007059 | chromosome segregation(GO:0007059) |
| 0.1 | 1.2 | GO:0043968 | histone H2A acetylation(GO:0043968) |
| 0.1 | 0.2 | GO:0006848 | pyruvate transport(GO:0006848) |
| 0.1 | 1.2 | GO:0006825 | copper ion transport(GO:0006825) |
| 0.1 | 0.2 | GO:0045056 | transcytosis(GO:0045056) |
| 0.1 | 0.2 | GO:0048537 | mucosal-associated lymphoid tissue development(GO:0048537) |
| 0.1 | 0.4 | GO:0042989 | sequestering of actin monomers(GO:0042989) |
| 0.1 | 0.4 | GO:0006072 | glycerol-3-phosphate metabolic process(GO:0006072) |
| 0.1 | 0.8 | GO:0030889 | negative regulation of B cell proliferation(GO:0030889) |
| 0.1 | 0.2 | GO:0006432 | phenylalanyl-tRNA aminoacylation(GO:0006432) |
| 0.1 | 0.4 | GO:0051096 | regulation of helicase activity(GO:0051095) positive regulation of helicase activity(GO:0051096) |
| 0.0 | 0.2 | GO:0043457 | regulation of cellular respiration(GO:0043457) |
| 0.0 | 0.3 | GO:0001514 | selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451) |
| 0.0 | 0.2 | GO:0031635 | adenylate cyclase-inhibiting opioid receptor signaling pathway(GO:0031635) opioid receptor signaling pathway(GO:0038003) |
| 0.0 | 0.2 | GO:0048669 | collateral sprouting in absence of injury(GO:0048669) |
| 0.0 | 0.3 | GO:0045116 | protein neddylation(GO:0045116) |
| 0.0 | 0.6 | GO:0021513 | spinal cord dorsal/ventral patterning(GO:0021513) |
| 0.0 | 0.2 | GO:0032020 | ISG15-protein conjugation(GO:0032020) |
| 0.0 | 0.4 | GO:0007635 | chemosensory behavior(GO:0007635) |
| 0.0 | 2.6 | GO:0001837 | epithelial to mesenchymal transition(GO:0001837) |
| 0.0 | 0.2 | GO:0070050 | neuron cellular homeostasis(GO:0070050) |
| 0.0 | 0.2 | GO:0050862 | positive regulation of T cell receptor signaling pathway(GO:0050862) |
| 0.0 | 0.1 | GO:0002679 | respiratory burst involved in defense response(GO:0002679) |
| 0.0 | 0.2 | GO:0007386 | compartment pattern specification(GO:0007386) |
| 0.0 | 0.4 | GO:0050435 | beta-amyloid metabolic process(GO:0050435) |
| 0.0 | 0.7 | GO:0006613 | cotranslational protein targeting to membrane(GO:0006613) |
| 0.0 | 1.1 | GO:0009083 | branched-chain amino acid catabolic process(GO:0009083) |
| 0.0 | 0.3 | GO:0034465 | cellular potassium ion homeostasis(GO:0030007) response to carbon monoxide(GO:0034465) negative regulation of cell volume(GO:0045794) |
| 0.0 | 0.6 | GO:0046827 | positive regulation of protein export from nucleus(GO:0046827) |
| 0.0 | 0.2 | GO:0032486 | Rap protein signal transduction(GO:0032486) |
| 0.0 | 0.9 | GO:0007158 | neuron cell-cell adhesion(GO:0007158) |
| 0.0 | 1.1 | GO:0050873 | brown fat cell differentiation(GO:0050873) |
| 0.0 | 0.1 | GO:1901522 | positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522) |
| 0.0 | 0.4 | GO:0006379 | mRNA cleavage(GO:0006379) |
| 0.0 | 0.3 | GO:0016255 | attachment of GPI anchor to protein(GO:0016255) |
| 0.0 | 1.3 | GO:0000725 | double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725) |
| 0.0 | 0.1 | GO:0000244 | spliceosomal tri-snRNP complex assembly(GO:0000244) |
| 0.0 | 1.5 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
| 0.0 | 0.1 | GO:0070544 | histone H3-K36 demethylation(GO:0070544) |
| 0.0 | 0.1 | GO:0014724 | regulation of twitch skeletal muscle contraction(GO:0014724) fast-twitch skeletal muscle fiber contraction(GO:0031443) regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) positive regulation of endoplasmic reticulum calcium ion concentration(GO:0032470) mitochondrial calcium ion homeostasis(GO:0051560) positive regulation of mitochondrial calcium ion concentration(GO:0051561) relaxation of skeletal muscle(GO:0090076) |
| 0.0 | 0.2 | GO:0008588 | release of cytoplasmic sequestered NF-kappaB(GO:0008588) |
| 0.0 | 0.5 | GO:0001502 | cartilage condensation(GO:0001502) cell aggregation(GO:0098743) |
| 0.0 | 0.6 | GO:0009790 | embryo development(GO:0009790) |
| 0.0 | 1.2 | GO:0060048 | cardiac muscle contraction(GO:0060048) |
| 0.0 | 0.5 | GO:0008625 | extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191) |
| 0.0 | 0.4 | GO:0006743 | ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) |
| 0.0 | 0.1 | GO:0001774 | microglial cell activation(GO:0001774) microglial cell activation involved in immune response(GO:0002282) |
| 0.0 | 0.0 | GO:0051970 | negative regulation of transmission of nerve impulse(GO:0051970) |
| 0.0 | 0.9 | GO:0043124 | negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124) |
| 0.0 | 0.2 | GO:0071157 | negative regulation of cell cycle arrest(GO:0071157) |
| 0.0 | 0.5 | GO:0016601 | Rac protein signal transduction(GO:0016601) |
| 0.0 | 0.2 | GO:0035590 | purinergic nucleotide receptor signaling pathway(GO:0035590) |
| 0.0 | 0.1 | GO:0006726 | eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474) |
| 0.0 | 0.4 | GO:0045730 | respiratory burst(GO:0045730) |
| 0.0 | 0.3 | GO:0071108 | protein K48-linked deubiquitination(GO:0071108) |
| 0.0 | 0.6 | GO:0030838 | positive regulation of actin filament polymerization(GO:0030838) |
| 0.0 | 0.4 | GO:0008635 | activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635) |
| 0.0 | 2.2 | GO:0006334 | nucleosome assembly(GO:0006334) |
| 0.0 | 0.1 | GO:0032672 | regulation of interleukin-3 production(GO:0032672) positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401) |
| 0.0 | 0.3 | GO:0006776 | vitamin A metabolic process(GO:0006776) |
| 0.0 | 0.9 | GO:0000080 | mitotic G1 phase(GO:0000080) |
| 0.0 | 0.3 | GO:0050930 | induction of positive chemotaxis(GO:0050930) |
| 0.0 | 0.4 | GO:0071230 | positive regulation of TOR signaling(GO:0032008) cellular response to amino acid stimulus(GO:0071230) |
| 0.0 | 0.4 | GO:0042359 | vitamin D metabolic process(GO:0042359) |
| 0.0 | 0.1 | GO:0060746 | maternal behavior(GO:0042711) parental behavior(GO:0060746) |
| 0.0 | 0.7 | GO:0015949 | nucleobase-containing small molecule interconversion(GO:0015949) |
| 0.0 | 0.6 | GO:0050892 | intestinal absorption(GO:0050892) |
| 0.0 | 0.1 | GO:0002430 | complement receptor mediated signaling pathway(GO:0002430) |
| 0.0 | 0.7 | GO:0065004 | protein-DNA complex assembly(GO:0065004) |
| 0.0 | 0.3 | GO:0030323 | respiratory tube development(GO:0030323) |
| 0.0 | 0.4 | GO:0051452 | intracellular pH reduction(GO:0051452) |
| 0.0 | 0.1 | GO:0045746 | negative regulation of Notch signaling pathway(GO:0045746) |
| 0.0 | 0.1 | GO:0033326 | cerebrospinal fluid secretion(GO:0033326) |
| 0.0 | 0.1 | GO:0090073 | positive regulation of protein homodimerization activity(GO:0090073) |
| 0.0 | 0.2 | GO:0033189 | response to vitamin A(GO:0033189) |
| 0.0 | 0.7 | GO:0071260 | cellular response to mechanical stimulus(GO:0071260) |
| 0.0 | 0.3 | GO:0032400 | melanosome localization(GO:0032400) |
| 0.0 | 0.3 | GO:0030321 | transepithelial chloride transport(GO:0030321) |
| 0.0 | 0.1 | GO:0032609 | interferon-gamma production(GO:0032609) regulation of interferon-gamma production(GO:0032649) positive regulation of interferon-gamma production(GO:0032729) |
| 0.0 | 0.1 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
| 0.0 | 0.3 | GO:0009268 | response to pH(GO:0009268) |
| 0.0 | 0.1 | GO:0009405 | pathogenesis(GO:0009405) |
| 0.0 | 0.1 | GO:0060081 | membrane hyperpolarization(GO:0060081) |
| 0.0 | 0.2 | GO:0015074 | DNA integration(GO:0015074) |
| 0.0 | 0.2 | GO:0006020 | inositol metabolic process(GO:0006020) |
| 0.0 | 0.0 | GO:0070309 | lens fiber cell morphogenesis(GO:0070309) |
| 0.0 | 0.1 | GO:0055062 | phosphate ion homeostasis(GO:0055062) divalent inorganic anion homeostasis(GO:0072505) trivalent inorganic anion homeostasis(GO:0072506) |
| 0.0 | 0.2 | GO:0007507 | heart development(GO:0007507) |
| 0.0 | 0.1 | GO:0051899 | membrane depolarization(GO:0051899) |
| 0.0 | 0.2 | GO:0050798 | activated T cell proliferation(GO:0050798) |
| 0.0 | 0.1 | GO:0007197 | adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) |
| 0.0 | 0.6 | GO:0005978 | glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250) |
| 0.0 | 0.3 | GO:0006829 | zinc II ion transport(GO:0006829) |
| 0.0 | 0.5 | GO:0007157 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) |
| 0.0 | 0.5 | GO:0048255 | RNA stabilization(GO:0043489) mRNA stabilization(GO:0048255) |
| 0.0 | 0.3 | GO:0034605 | cellular response to heat(GO:0034605) |
| 0.0 | 0.1 | GO:0019509 | L-methionine biosynthetic process from methylthioadenosine(GO:0019509) |
| 0.0 | 0.5 | GO:0051925 | obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925) |
| 0.0 | 0.3 | GO:0000380 | alternative mRNA splicing, via spliceosome(GO:0000380) |
| 0.0 | 0.0 | GO:0021904 | dorsal/ventral neural tube patterning(GO:0021904) |
| 0.0 | 0.0 | GO:0002002 | regulation of angiotensin levels in blood(GO:0002002) regulation of angiotensin metabolic process(GO:0060177) |
| 0.0 | 1.2 | GO:0031295 | lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295) |
| 0.0 | 0.4 | GO:0006783 | heme biosynthetic process(GO:0006783) |
| 0.0 | 0.0 | GO:0050708 | regulation of protein secretion(GO:0050708) |
| 0.0 | 0.1 | GO:0051453 | regulation of intracellular pH(GO:0051453) |
| 0.0 | 3.8 | GO:0007517 | muscle organ development(GO:0007517) |
| 0.0 | 0.5 | GO:0051693 | actin filament capping(GO:0051693) |
| 0.0 | 0.6 | GO:0006626 | protein targeting to mitochondrion(GO:0006626) |
| 0.0 | 0.2 | GO:0001701 | in utero embryonic development(GO:0001701) |
| 0.0 | 0.0 | GO:0000917 | barrier septum assembly(GO:0000917) cell septum assembly(GO:0090529) mitotic cytokinetic process(GO:1902410) |
| 0.0 | 0.5 | GO:0006362 | transcription elongation from RNA polymerase I promoter(GO:0006362) |
| 0.0 | 3.5 | GO:0006936 | muscle contraction(GO:0006936) |
| 0.0 | 0.2 | GO:0008105 | asymmetric protein localization(GO:0008105) |
| 0.0 | 0.4 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
| 0.0 | 0.1 | GO:0046121 | deoxyribonucleoside catabolic process(GO:0046121) |
| 0.0 | 0.7 | GO:0031124 | mRNA 3'-end processing(GO:0031124) |
| 0.0 | 0.2 | GO:0007188 | adenylate cyclase-modulating G-protein coupled receptor signaling pathway(GO:0007188) |
| 0.0 | 0.1 | GO:0071459 | protein localization to kinetochore(GO:0034501) protein localization to chromosome, centromeric region(GO:0071459) |
| 0.0 | 0.2 | GO:0046777 | protein autophosphorylation(GO:0046777) |
| 0.0 | 0.3 | GO:0090263 | positive regulation of canonical Wnt signaling pathway(GO:0090263) |
| 0.0 | 0.5 | GO:0007193 | adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193) |
| 0.0 | 0.1 | GO:0007271 | synaptic transmission, cholinergic(GO:0007271) |
| 0.0 | 0.1 | GO:0070293 | renal absorption(GO:0070293) renal water absorption(GO:0070295) |
| 0.0 | 0.3 | GO:0042733 | embryonic digit morphogenesis(GO:0042733) |
| 0.0 | 0.7 | GO:0006914 | autophagy(GO:0006914) |
| 0.0 | 0.3 | GO:0042267 | natural killer cell mediated immunity(GO:0002228) natural killer cell mediated cytotoxicity(GO:0042267) |
| 0.0 | 0.0 | GO:0031580 | membrane raft polarization(GO:0001766) membrane raft organization(GO:0031579) membrane raft distribution(GO:0031580) |
| 0.0 | 0.1 | GO:0060100 | regulation of phagocytosis, engulfment(GO:0060099) positive regulation of phagocytosis, engulfment(GO:0060100) regulation of membrane invagination(GO:1905153) positive regulation of membrane invagination(GO:1905155) |
| 0.0 | 1.0 | GO:0007608 | sensory perception of smell(GO:0007608) |
| 0.0 | 0.7 | GO:0006968 | cellular defense response(GO:0006968) |
| 0.0 | 0.3 | GO:0048168 | regulation of neuronal synaptic plasticity(GO:0048168) |
| 0.0 | 0.1 | GO:0007598 | blood coagulation, extrinsic pathway(GO:0007598) |
| 0.0 | 0.1 | GO:0017121 | phospholipid scrambling(GO:0017121) |
| 0.0 | 0.6 | GO:0019722 | calcium-mediated signaling(GO:0019722) |
| 0.0 | 0.2 | GO:0032784 | regulation of DNA-templated transcription, elongation(GO:0032784) |
| 0.0 | 0.3 | GO:0046329 | negative regulation of JNK cascade(GO:0046329) |
| 0.0 | 0.2 | GO:0051568 | histone H3-K4 methylation(GO:0051568) |
| 0.0 | 0.9 | GO:0000070 | mitotic sister chromatid segregation(GO:0000070) |
| 0.0 | 0.1 | GO:0042517 | positive regulation of tyrosine phosphorylation of Stat3 protein(GO:0042517) |
| 0.0 | 0.0 | GO:0015854 | guanine transport(GO:0015854) hypoxanthine transport(GO:0035344) thymine transport(GO:0035364) |
| 0.0 | 0.3 | GO:0051101 | regulation of DNA binding(GO:0051101) |
| 0.0 | 0.1 | GO:0032472 | cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) Golgi calcium ion transport(GO:0032472) manganese ion homeostasis(GO:0055071) |
| 0.0 | 0.1 | GO:0009313 | oligosaccharide catabolic process(GO:0009313) |
| 0.0 | 0.3 | GO:0006730 | one-carbon metabolic process(GO:0006730) |
| 0.0 | 0.2 | GO:0042771 | intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771) |
| 0.0 | 0.1 | GO:0006012 | galactose metabolic process(GO:0006012) |
| 0.0 | 0.2 | GO:0071804 | cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 12.4 | GO:0098647 | collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647) |
| 0.4 | 1.6 | GO:0005712 | chiasma(GO:0005712) MutLbeta complex(GO:0032390) |
| 0.4 | 10.6 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
| 0.4 | 1.8 | GO:0042405 | nuclear inclusion body(GO:0042405) |
| 0.3 | 1.8 | GO:0005945 | 6-phosphofructokinase complex(GO:0005945) |
| 0.3 | 1.2 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
| 0.2 | 1.7 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
| 0.2 | 0.6 | GO:0001650 | fibrillar center(GO:0001650) |
| 0.2 | 0.6 | GO:0071256 | Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256) |
| 0.1 | 1.5 | GO:0030990 | intraciliary transport particle(GO:0030990) |
| 0.1 | 2.6 | GO:0042613 | MHC class II protein complex(GO:0042613) |
| 0.1 | 0.4 | GO:0000120 | RNA polymerase I transcription factor complex(GO:0000120) |
| 0.1 | 3.2 | GO:0016010 | dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665) |
| 0.1 | 0.4 | GO:0072669 | tRNA-splicing ligase complex(GO:0072669) |
| 0.1 | 0.6 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) |
| 0.1 | 0.6 | GO:0045179 | apical cortex(GO:0045179) |
| 0.1 | 0.5 | GO:0005947 | mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) |
| 0.1 | 1.0 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
| 0.1 | 1.0 | GO:0098643 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
| 0.1 | 0.3 | GO:0042765 | GPI-anchor transamidase complex(GO:0042765) |
| 0.1 | 0.3 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.1 | 0.9 | GO:0005678 | obsolete chromatin assembly complex(GO:0005678) |
| 0.1 | 1.1 | GO:0005833 | hemoglobin complex(GO:0005833) |
| 0.1 | 0.4 | GO:0009331 | glycerol-3-phosphate dehydrogenase complex(GO:0009331) |
| 0.1 | 0.8 | GO:0043202 | lysosomal lumen(GO:0043202) |
| 0.1 | 3.7 | GO:0015030 | Cajal body(GO:0015030) |
| 0.1 | 0.3 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 0.1 | 0.3 | GO:0031205 | endoplasmic reticulum Sec complex(GO:0031205) |
| 0.1 | 0.3 | GO:0032807 | DNA ligase IV complex(GO:0032807) |
| 0.1 | 0.2 | GO:0010370 | perinucleolar chromocenter(GO:0010370) |
| 0.1 | 0.7 | GO:0042555 | MCM complex(GO:0042555) |
| 0.1 | 2.7 | GO:0000786 | nucleosome(GO:0000786) |
| 0.0 | 1.2 | GO:0030140 | trans-Golgi network transport vesicle(GO:0030140) |
| 0.0 | 0.7 | GO:0071203 | WASH complex(GO:0071203) |
| 0.0 | 1.1 | GO:0032420 | stereocilium(GO:0032420) |
| 0.0 | 0.4 | GO:0031430 | M band(GO:0031430) |
| 0.0 | 1.3 | GO:0005859 | muscle myosin complex(GO:0005859) |
| 0.0 | 0.4 | GO:0030681 | nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681) |
| 0.0 | 0.6 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
| 0.0 | 0.4 | GO:0042575 | DNA polymerase complex(GO:0042575) |
| 0.0 | 0.7 | GO:0001527 | microfibril(GO:0001527) |
| 0.0 | 0.2 | GO:0051233 | spindle midzone(GO:0051233) |
| 0.0 | 0.1 | GO:0005686 | U2 snRNP(GO:0005686) |
| 0.0 | 0.3 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 0.0 | 1.0 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 0.0 | 0.1 | GO:0033011 | perinuclear theca(GO:0033011) cytoskeletal calyx(GO:0033150) |
| 0.0 | 0.4 | GO:0005606 | laminin-1 complex(GO:0005606) |
| 0.0 | 0.6 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
| 0.0 | 0.7 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
| 0.0 | 0.3 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
| 0.0 | 0.2 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.0 | 0.1 | GO:0033093 | Weibel-Palade body(GO:0033093) |
| 0.0 | 0.1 | GO:0005663 | DNA replication factor C complex(GO:0005663) |
| 0.0 | 0.9 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.0 | 0.3 | GO:0042589 | phagocytic vesicle membrane(GO:0030670) zymogen granule membrane(GO:0042589) |
| 0.0 | 0.4 | GO:0030660 | Golgi-associated vesicle membrane(GO:0030660) |
| 0.0 | 0.5 | GO:0000299 | obsolete integral to membrane of membrane fraction(GO:0000299) |
| 0.0 | 0.4 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 0.0 | 0.1 | GO:0000800 | lateral element(GO:0000800) |
| 0.0 | 0.7 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 0.0 | 0.5 | GO:0005689 | U12-type spliceosomal complex(GO:0005689) |
| 0.0 | 0.7 | GO:0005657 | replication fork(GO:0005657) |
| 0.0 | 0.4 | GO:0042581 | specific granule(GO:0042581) |
| 0.0 | 0.1 | GO:0005687 | U4 snRNP(GO:0005687) |
| 0.0 | 0.1 | GO:0042382 | paraspeckles(GO:0042382) |
| 0.0 | 0.2 | GO:0005869 | dynactin complex(GO:0005869) |
| 0.0 | 0.1 | GO:0032982 | myosin filament(GO:0032982) |
| 0.0 | 0.9 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.0 | 0.3 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
| 0.0 | 0.5 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.0 | 0.1 | GO:0033162 | melanosome membrane(GO:0033162) chitosome(GO:0045009) |
| 0.0 | 0.8 | GO:0009898 | cytoplasmic side of plasma membrane(GO:0009898) cytoplasmic side of membrane(GO:0098562) |
| 0.0 | 0.8 | GO:0031970 | mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970) |
| 0.0 | 0.2 | GO:0048188 | Set1C/COMPASS complex(GO:0048188) |
| 0.0 | 0.2 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.0 | 0.3 | GO:0042101 | T cell receptor complex(GO:0042101) |
| 0.0 | 0.2 | GO:0030897 | HOPS complex(GO:0030897) |
| 0.0 | 0.5 | GO:0030530 | obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530) |
| 0.0 | 0.6 | GO:0005637 | nuclear inner membrane(GO:0005637) |
| 0.0 | 0.1 | GO:0042584 | chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584) |
| 0.0 | 0.0 | GO:0005873 | plus-end kinesin complex(GO:0005873) |
| 0.0 | 0.1 | GO:0043073 | germ cell nucleus(GO:0043073) |
| 0.0 | 0.3 | GO:0044853 | caveola(GO:0005901) plasma membrane raft(GO:0044853) |
| 0.0 | 0.2 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
| 0.0 | 0.0 | GO:0000221 | vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221) |
| 0.0 | 0.1 | GO:0008278 | cohesin complex(GO:0008278) |
| 0.0 | 1.3 | GO:0001726 | ruffle(GO:0001726) |
| 0.0 | 0.1 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.0 | 1.0 | GO:0016922 | ligand-dependent nuclear receptor binding(GO:0016922) |
| 0.5 | 1.5 | GO:0030611 | arsenate reductase activity(GO:0030611) |
| 0.4 | 2.7 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
| 0.3 | 10.1 | GO:0005246 | calcium channel regulator activity(GO:0005246) |
| 0.3 | 1.0 | GO:0047273 | galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273) |
| 0.3 | 0.3 | GO:0003990 | acetylcholinesterase activity(GO:0003990) |
| 0.3 | 1.8 | GO:0003872 | 6-phosphofructokinase activity(GO:0003872) |
| 0.2 | 1.5 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
| 0.2 | 1.0 | GO:0004666 | prostaglandin-endoperoxide synthase activity(GO:0004666) |
| 0.2 | 0.9 | GO:0008112 | nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760) |
| 0.2 | 0.9 | GO:0016531 | copper chaperone activity(GO:0016531) |
| 0.2 | 1.6 | GO:0032137 | guanine/thymine mispair binding(GO:0032137) |
| 0.2 | 1.2 | GO:0005499 | vitamin D binding(GO:0005499) |
| 0.2 | 8.0 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.2 | 2.6 | GO:0032395 | MHC class II receptor activity(GO:0032395) |
| 0.2 | 1.4 | GO:0016778 | diphosphotransferase activity(GO:0016778) |
| 0.2 | 0.7 | GO:0008466 | glycogenin glucosyltransferase activity(GO:0008466) |
| 0.2 | 0.7 | GO:0004083 | bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619) |
| 0.2 | 0.8 | GO:0004830 | tryptophan-tRNA ligase activity(GO:0004830) |
| 0.2 | 0.5 | GO:0003863 | alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863) |
| 0.2 | 1.7 | GO:0016857 | racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857) |
| 0.2 | 0.5 | GO:0004781 | adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781) |
| 0.1 | 0.6 | GO:0043398 | HLH domain binding(GO:0043398) |
| 0.1 | 0.4 | GO:0008476 | protein-tyrosine sulfotransferase activity(GO:0008476) |
| 0.1 | 2.3 | GO:0050786 | RAGE receptor binding(GO:0050786) |
| 0.1 | 0.6 | GO:0015254 | glycerol channel activity(GO:0015254) |
| 0.1 | 0.4 | GO:0031686 | A1 adenosine receptor binding(GO:0031686) |
| 0.1 | 0.4 | GO:0003870 | 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749) |
| 0.1 | 0.6 | GO:0005324 | long-chain fatty acid transporter activity(GO:0005324) |
| 0.1 | 0.4 | GO:0004821 | histidine-tRNA ligase activity(GO:0004821) |
| 0.1 | 0.7 | GO:0004558 | alpha-1,4-glucosidase activity(GO:0004558) |
| 0.1 | 2.2 | GO:0005031 | tumor necrosis factor-activated receptor activity(GO:0005031) |
| 0.1 | 0.4 | GO:0045155 | electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155) |
| 0.1 | 3.1 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.1 | 1.2 | GO:0070513 | death domain binding(GO:0070513) |
| 0.1 | 1.3 | GO:0030247 | pattern binding(GO:0001871) polysaccharide binding(GO:0030247) |
| 0.1 | 0.6 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
| 0.1 | 0.4 | GO:0052590 | sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591) |
| 0.1 | 0.3 | GO:0002114 | interleukin-33 receptor activity(GO:0002114) |
| 0.1 | 1.0 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
| 0.1 | 0.4 | GO:0004883 | glucocorticoid receptor activity(GO:0004883) |
| 0.1 | 0.3 | GO:0003923 | GPI-anchor transamidase activity(GO:0003923) |
| 0.1 | 1.1 | GO:0005344 | oxygen transporter activity(GO:0005344) |
| 0.1 | 0.5 | GO:0001968 | fibronectin binding(GO:0001968) |
| 0.1 | 1.3 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.1 | 0.3 | GO:0004132 | dCMP deaminase activity(GO:0004132) |
| 0.1 | 0.4 | GO:0004692 | cGMP-dependent protein kinase activity(GO:0004692) |
| 0.1 | 1.0 | GO:0016175 | superoxide-generating NADPH oxidase activity(GO:0016175) |
| 0.1 | 1.0 | GO:0004526 | ribonuclease P activity(GO:0004526) |
| 0.1 | 0.2 | GO:0042296 | ISG15 transferase activity(GO:0042296) |
| 0.1 | 0.2 | GO:0005224 | ATP-binding and phosphorylation-dependent chloride channel activity(GO:0005224) channel-conductance-controlling ATPase activity(GO:0005260) |
| 0.1 | 0.7 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
| 0.1 | 1.1 | GO:0016289 | CoA hydrolase activity(GO:0016289) |
| 0.1 | 1.1 | GO:0017127 | cholesterol transporter activity(GO:0017127) |
| 0.1 | 0.2 | GO:0035276 | ethanol binding(GO:0035276) |
| 0.1 | 0.3 | GO:0047315 | kynurenine-glyoxylate transaminase activity(GO:0047315) |
| 0.1 | 0.8 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, RNA polymerase II basal transcription factor binding(GO:0001083) transcription factor activity, TFIIB-class binding(GO:0001087) RNA polymerase II basal transcription factor binding(GO:0001091) TFIIB-class transcription factor binding(GO:0001093) |
| 0.1 | 0.2 | GO:0043008 | ATP-dependent protein binding(GO:0043008) |
| 0.1 | 1.1 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
| 0.1 | 0.2 | GO:0019788 | NEDD8 transferase activity(GO:0019788) |
| 0.1 | 0.2 | GO:0008332 | low voltage-gated calcium channel activity(GO:0008332) |
| 0.1 | 0.3 | GO:0015038 | glutathione disulfide oxidoreductase activity(GO:0015038) |
| 0.1 | 0.6 | GO:0008527 | taste receptor activity(GO:0008527) |
| 0.1 | 0.2 | GO:0050833 | pyruvate secondary active transmembrane transporter activity(GO:0005477) pyruvate transmembrane transporter activity(GO:0050833) |
| 0.1 | 0.3 | GO:0003917 | DNA topoisomerase type I activity(GO:0003917) |
| 0.1 | 1.4 | GO:0004708 | MAP kinase kinase activity(GO:0004708) |
| 0.1 | 0.1 | GO:0016901 | oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901) |
| 0.1 | 0.9 | GO:0005522 | profilin binding(GO:0005522) |
| 0.1 | 2.9 | GO:0003678 | DNA helicase activity(GO:0003678) |
| 0.1 | 2.6 | GO:0003899 | DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062) |
| 0.1 | 0.6 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
| 0.0 | 0.6 | GO:0015450 | P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450) |
| 0.0 | 1.6 | GO:0004385 | guanylate kinase activity(GO:0004385) |
| 0.0 | 0.3 | GO:0003910 | DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910) |
| 0.0 | 0.3 | GO:0004800 | thyroxine 5'-deiodinase activity(GO:0004800) |
| 0.0 | 0.2 | GO:0003680 | AT DNA binding(GO:0003680) |
| 0.0 | 0.2 | GO:0008907 | integrase activity(GO:0008907) |
| 0.0 | 0.2 | GO:0004988 | obsolete mu-opioid receptor activity(GO:0004988) |
| 0.0 | 0.6 | GO:0042166 | acetylcholine binding(GO:0042166) |
| 0.0 | 0.7 | GO:0030276 | clathrin binding(GO:0030276) |
| 0.0 | 0.1 | GO:0017130 | poly(C) RNA binding(GO:0017130) |
| 0.0 | 0.7 | GO:0070888 | E-box binding(GO:0070888) |
| 0.0 | 0.3 | GO:0050733 | RS domain binding(GO:0050733) |
| 0.0 | 0.3 | GO:0060072 | large conductance calcium-activated potassium channel activity(GO:0060072) |
| 0.0 | 0.3 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.0 | 0.4 | GO:0030515 | snoRNA binding(GO:0030515) |
| 0.0 | 0.5 | GO:0051637 | obsolete Gram-positive bacterial cell surface binding(GO:0051637) |
| 0.0 | 0.6 | GO:0015125 | bile acid transmembrane transporter activity(GO:0015125) |
| 0.0 | 1.9 | GO:0017048 | Rho GTPase binding(GO:0017048) |
| 0.0 | 0.8 | GO:0008395 | steroid hydroxylase activity(GO:0008395) |
| 0.0 | 0.2 | GO:0003951 | NAD+ kinase activity(GO:0003951) |
| 0.0 | 0.1 | GO:0033858 | N-acetylgalactosamine kinase activity(GO:0033858) |
| 0.0 | 0.2 | GO:0004826 | phenylalanine-tRNA ligase activity(GO:0004826) |
| 0.0 | 0.4 | GO:0003701 | obsolete RNA polymerase I transcription factor activity(GO:0003701) |
| 0.0 | 0.2 | GO:0005176 | ErbB-2 class receptor binding(GO:0005176) |
| 0.0 | 1.0 | GO:0008656 | cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656) |
| 0.0 | 0.1 | GO:0032139 | dinucleotide insertion or deletion binding(GO:0032139) |
| 0.0 | 1.2 | GO:0005507 | copper ion binding(GO:0005507) |
| 0.0 | 0.2 | GO:0000827 | inositol-1,3,4,5,6-pentakisphosphate kinase activity(GO:0000827) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857) |
| 0.0 | 0.3 | GO:0003688 | DNA replication origin binding(GO:0003688) |
| 0.0 | 0.3 | GO:0008113 | peptide-methionine (S)-S-oxide reductase activity(GO:0008113) |
| 0.0 | 0.3 | GO:0004579 | dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
| 0.0 | 1.1 | GO:0005048 | signal sequence binding(GO:0005048) |
| 0.0 | 0.2 | GO:0046934 | phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813) |
| 0.0 | 0.1 | GO:0030197 | extracellular matrix constituent, lubricant activity(GO:0030197) |
| 0.0 | 0.4 | GO:0008242 | omega peptidase activity(GO:0008242) |
| 0.0 | 0.2 | GO:0033130 | acetylcholine receptor binding(GO:0033130) |
| 0.0 | 0.1 | GO:0019763 | immunoglobulin receptor activity(GO:0019763) |
| 0.0 | 0.5 | GO:0016408 | C-acyltransferase activity(GO:0016408) |
| 0.0 | 0.1 | GO:0003689 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
| 0.0 | 1.3 | GO:0008009 | chemokine activity(GO:0008009) |
| 0.0 | 0.5 | GO:0008484 | sulfuric ester hydrolase activity(GO:0008484) |
| 0.0 | 0.7 | GO:0004623 | phospholipase A2 activity(GO:0004623) |
| 0.0 | 0.4 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
| 0.0 | 0.2 | GO:0008494 | translation activator activity(GO:0008494) |
| 0.0 | 1.1 | GO:0004984 | olfactory receptor activity(GO:0004984) |
| 0.0 | 0.2 | GO:0042800 | histone methyltransferase activity (H3-K4 specific)(GO:0042800) |
| 0.0 | 0.8 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
| 0.0 | 0.5 | GO:0070742 | C2H2 zinc finger domain binding(GO:0070742) |
| 0.0 | 0.1 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 0.0 | 0.1 | GO:0005436 | sodium:phosphate symporter activity(GO:0005436) |
| 0.0 | 0.1 | GO:0005229 | intracellular calcium activated chloride channel activity(GO:0005229) |
| 0.0 | 0.2 | GO:0001758 | retinal dehydrogenase activity(GO:0001758) |
| 0.0 | 0.6 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 0.0 | 0.1 | GO:0015386 | potassium:proton antiporter activity(GO:0015386) |
| 0.0 | 0.2 | GO:0035381 | extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) |
| 0.0 | 0.1 | GO:0004738 | pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739) |
| 0.0 | 0.4 | GO:0042288 | MHC class I protein binding(GO:0042288) |
| 0.0 | 0.1 | GO:0004875 | complement receptor activity(GO:0004875) |
| 0.0 | 0.2 | GO:0016421 | CoA carboxylase activity(GO:0016421) |
| 0.0 | 0.1 | GO:0004139 | deoxyribose-phosphate aldolase activity(GO:0004139) |
| 0.0 | 0.1 | GO:0017163 | obsolete basal transcription repressor activity(GO:0017163) |
| 0.0 | 0.1 | GO:0031434 | mitogen-activated protein kinase kinase binding(GO:0031434) |
| 0.0 | 0.2 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.0 | 0.1 | GO:0008499 | UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499) |
| 0.0 | 0.1 | GO:0008649 | rRNA methyltransferase activity(GO:0008649) |
| 0.0 | 0.9 | GO:0003823 | antigen binding(GO:0003823) |
| 0.0 | 0.9 | GO:0005158 | insulin receptor binding(GO:0005158) |
| 0.0 | 0.1 | GO:0042609 | CD4 receptor binding(GO:0042609) |
| 0.0 | 0.1 | GO:0031432 | titin binding(GO:0031432) |
| 0.0 | 0.1 | GO:0008266 | poly(U) RNA binding(GO:0008266) |
| 0.0 | 0.2 | GO:1901567 | icosanoid binding(GO:0050542) icosatetraenoic acid binding(GO:0050543) arachidonic acid binding(GO:0050544) fatty acid derivative binding(GO:1901567) |
| 0.0 | 0.2 | GO:0003711 | obsolete transcription elongation regulator activity(GO:0003711) |
| 0.0 | 1.4 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 0.0 | 0.2 | GO:0043395 | heparan sulfate proteoglycan binding(GO:0043395) |
| 0.0 | 0.1 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
| 0.0 | 0.1 | GO:0022890 | inorganic cation transmembrane transporter activity(GO:0022890) |
| 0.0 | 0.1 | GO:0070568 | guanylyltransferase activity(GO:0070568) |
| 0.0 | 0.1 | GO:0051864 | histone demethylase activity (H3-K36 specific)(GO:0051864) |
| 0.0 | 0.4 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.0 | 0.1 | GO:0035240 | dopamine binding(GO:0035240) |
| 0.0 | 0.1 | GO:0005338 | nucleotide-sugar transmembrane transporter activity(GO:0005338) |
| 0.0 | 0.0 | GO:0050528 | acyloxyacyl hydrolase activity(GO:0050528) |
| 0.0 | 0.8 | GO:0032947 | protein complex scaffold(GO:0032947) |
| 0.0 | 0.2 | GO:0050780 | dopamine receptor binding(GO:0050780) |
| 0.0 | 0.1 | GO:0008518 | reduced folate carrier activity(GO:0008518) |
| 0.0 | 0.6 | GO:0004860 | protein kinase inhibitor activity(GO:0004860) |
| 0.0 | 0.1 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
| 0.0 | 0.1 | GO:0004117 | calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) |
| 0.0 | 0.4 | GO:0016709 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709) |
| 0.0 | 0.0 | GO:0035243 | protein-arginine omega-N symmetric methyltransferase activity(GO:0035243) |
| 0.0 | 0.2 | GO:0051920 | peroxiredoxin activity(GO:0051920) |
| 0.0 | 0.2 | GO:0004691 | cyclic nucleotide-dependent protein kinase activity(GO:0004690) cAMP-dependent protein kinase activity(GO:0004691) |
| 0.0 | 0.1 | GO:0008271 | secondary active sulfate transmembrane transporter activity(GO:0008271) |
| 0.0 | 0.1 | GO:0045029 | UDP-activated nucleotide receptor activity(GO:0045029) |
| 0.0 | 0.1 | GO:0005131 | growth hormone receptor binding(GO:0005131) |
| 0.0 | 0.1 | GO:0016715 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715) |
| 0.0 | 0.2 | GO:0017069 | snRNA binding(GO:0017069) |
| 0.0 | 0.1 | GO:0030618 | transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618) |
| 0.0 | 0.1 | GO:0005496 | steroid binding(GO:0005496) |
| 0.0 | 2.2 | GO:0003690 | double-stranded DNA binding(GO:0003690) |
| 0.0 | 0.0 | GO:0005113 | patched binding(GO:0005113) |
| 0.0 | 0.1 | GO:0017128 | phospholipid scramblase activity(GO:0017128) |
| 0.0 | 0.4 | GO:0008308 | voltage-gated anion channel activity(GO:0008308) |
| 0.0 | 0.9 | GO:0047485 | protein N-terminus binding(GO:0047485) |
| 0.0 | 0.4 | GO:0003697 | single-stranded DNA binding(GO:0003697) |
| 0.0 | 0.1 | GO:0015321 | sodium-dependent phosphate transmembrane transporter activity(GO:0015321) |
| 0.0 | 0.5 | GO:0004402 | histone acetyltransferase activity(GO:0004402) |
| 0.0 | 0.2 | GO:0042162 | telomeric DNA binding(GO:0042162) |
| 0.0 | 0.3 | GO:0016251 | obsolete general RNA polymerase II transcription factor activity(GO:0016251) |
| 0.0 | 0.1 | GO:0008454 | alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454) |
| 0.0 | 0.1 | GO:0008107 | galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127) |
| 0.0 | 0.1 | GO:0015410 | manganese-transporting ATPase activity(GO:0015410) |
| 0.0 | 0.1 | GO:0016907 | G-protein coupled acetylcholine receptor activity(GO:0016907) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.8 | SIG_IL4RECEPTOR_IN_B_LYPHOCYTES | Genes related to IL4 rceptor signaling in B lymphocytes |
| 0.1 | 2.1 | SA_MMP_CYTOKINE_CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 0.1 | 0.7 | SA_G2_AND_M_PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
| 0.0 | 1.2 | ST_MYOCYTE_AD_PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
| 0.0 | 2.9 | SIG_BCR_SIGNALING_PATHWAY | Members of the BCR signaling pathway |
| 0.0 | 1.5 | ST_P38_MAPK_PATHWAY | p38 MAPK Pathway |
| 0.0 | 0.1 | SA_TRKA_RECEPTOR | The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth. |
| 0.0 | 0.1 | ST_IL_13_PATHWAY | Interleukin 13 (IL-13) Pathway |
| 0.0 | 0.1 | ST_G_ALPHA_S_PATHWAY | G alpha s Pathway |
| 0.0 | 0.8 | ST_T_CELL_SIGNAL_TRANSDUCTION | T Cell Signal Transduction |
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